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3173, 3193, 3205, 3298, 3302, 3314, 3337, 3341, 3345, 3362, 3369, 3383, 3443, 3486, 3542, 3554, 3604, 3607, 3613, 3616, 3620, 3628, 3638, 3641, 3649, 3652, 3655, 3659, 3663, 3668, 3719, 3747, 3750, 3764, 3768, 3772, 3782, 3795, 3801, 3812, 3816, 3826, 3829, 3837, 3840, 3861, 3872, 3875, 3878, 3902, 3952, 3966, 4003, 4086, 4096, 4164, 4182, 4204, 4217, 4228, 4237, 4241, 4297, 4311, 4328, 4380, 4384, 4392, 4398, 4401, 4408, 4419, 4429, 4438, 4449, 4453, 4525, 4531, 4539, 4579, 4678, 4681, 4699, 4702, 4722, 4871, 4892, 4896, 4900, 4917, 4943, 4950, 4988, 5022, 5025, 5045, 5051, 5227, 5290, 5296, 5338, 5401, 5422, 5429, 5432, 5442, 5451, 5454, 5458, 5471, 5485, 5498, 5507, 5511, 5514, 5520], 'expression': [4, 162, 233, 249, 407, 478, 991, 1048, 1141, 1647, 1933, 2031, 2044, 2100, 2130, 2145, 2859, 3164, 3441, 3723, 3748, 3859, 4390, 4447, 4540, 5046, 5332, 5430, 5443, 5499], 'of': [5, 99, 111, 128, 134, 163, 185, 195, 205, 209, 221, 234, 250, 344, 356, 373, 379, 408, 430, 440, 450, 454, 466, 479, 511, 556, 561, 571, 575, 609, 767, 807, 820, 980, 992, 1001, 1008, 1019, 1029, 1049, 1056, 1128, 1134, 1142, 1182, 1302, 1322, 1471, 1546, 1591, 1625, 1641, 1648, 1654, 1788, 1832, 1893, 2025, 2032, 2045, 2054, 2058, 2064, 2076, 2084, 2090, 2101, 2114, 2120, 2131, 2146, 2151, 2163, 2175, 2180, 2194, 2277, 2286, 2314, 2323, 2331, 2387, 2397, 2401, 2470, 2509, 2514, 2543, 2566, 2573, 2585, 2612, 2619, 2628, 2646, 2737, 2746, 2754, 2771, 2782, 2792, 2798, 2813, 2818, 2827, 2840, 2855, 2860, 2871, 2882, 2897, 2912, 2921, 2932, 2958, 2970, 2984, 3041, 3052, 3067, 3077, 3082, 3088, 3141, 3165, 3175, 3178, 3195, 3207, 3252, 3297, 3301, 3327, 3336, 3344, 3385, 3442, 3485, 3546, 3606, 3619, 3627, 3640, 3646, 3651, 3658, 3665, 3667, 3721, 3749, 3771, 3784, 3790, 3803, 3819, 3828, 3839, 3847, 3860, 3874, 3877, 3910, 3955, 3960, 3970, 3974, 4008, 4166, 4206, 4219, 4379, 4391, 4400, 4407, 4418, 4428, 4448, 4455, 4527, 4533, 4541, 4581, 4701, 4721, 4870, 4945, 4990, 5024, 5040, 5047, 5053, 5187, 5231, 5292, 5424, 5431, 5444, 5453, 5457, 5463, 5475, 5483, 5489, 5500, 5513, 5519], 'pWW0': [7, 252, 845, 4244], 'plasmid': [8, 253, 846, 4245], 'genes': [9, 129, 165, 176, 208, 254, 374, 410, 421, 453, 839, 895, 1475, 1649, 1997, 2047, 2067, 2102, 2134, 2179, 2203, 2293, 2298, 2348, 2415, 2623, 2800, 2863, 2885, 3017, 3167, 3197, 3300, 3338, 3366, 3487, 3864, 4238, 4294, 4874, 5048, 5396, 5446, 5466, 5501], 'for': [10, 103, 131, 255, 348, 376, 699, 831, 897, 1111, 1117, 2200, 2608, 2708, 3033, 3131, 3144, 3151, 3310, 3324, 3447, 3492, 3767, 4098, 4230, 4296, 4510, 4516], 'toluene/xylene': [12, 236, 257, 481, 1304, 4703], 'assimilation': [13, 258, 597, 608, 819, 835, 1305, 1653, 2075, 3996, 4007, 4218, 4234, 4704, 5052, 5474], 'pathway': [14, 198, 259, 443, 830, 878, 994, 1004, 1280, 1307, 1474, 1996, 2035, 2060, 2282, 2289, 2317, 2590, 2622, 2649, 2785, 3365, 3374, 3378, 3387, 3446, 3653, 3660, 3669, 3752, 3773, 3841, 3863, 3880, 4229, 4277, 4393, 4403, 4679, 4706, 4873, 5395, 5434, 5459], '(the': [15, 260], 'TOL': [16, 75, 113, 175, 197, 261, 320, 358, 420, 442, 1627, 1995, 2034, 2133, 2281, 2288, 2316, 2862, 3751, 3862, 3879, 5026, 5394, 5433], 'pathway)': [17, 262], 'is': [18, 68, 144, 170, 263, 313, 389, 415, 492, 668, 774, 1168, 1246, 1298, 1308, 1315, 1480, 1618, 1637, 1791, 1818, 2080, 2155, 2520, 2598, 2655, 2728, 2775, 2807, 2864, 2974, 3204, 3292, 3379, 3559, 3697, 3713, 3853, 3891, 4067, 4173, 4567, 4645, 4697, 4707, 4714, 4879, 5017, 5036, 5190, 5217, 5479], 'subject': [19, 264], 'to': [20, 25, 46, 91, 265, 270, 291, 336, 505, 541, 552, 770, 782, 800, 884, 1175, 1278, 1318, 1593, 1792, 1909, 2001, 2006, 2336, 2343, 2466, 2548, 2559, 2666, 2741, 2756, 2803, 2809, 2867, 2889, 2899, 2946, 2999, 3700, 3705, 3762, 3800, 3904, 3940, 3951, 4169, 4181, 4199, 4283, 4574, 4677, 4717, 4992, 5191, 5308, 5400, 5405], 'complex': [21, 266, 3788], 'regulation': [22, 267, 563, 1484, 2088, 2285, 3087, 3335, 3696, 3720, 3770, 3791, 3820, 3876, 3962, 4883, 5487], 'in': [23, 58, 64, 177, 217, 268, 303, 309, 422, 462, 676, 703, 780, 795, 810, 813, 892, 911, 928, 935, 1125, 1131, 1179, 1244, 1276, 1487, 1651, 1896, 1934, 2071, 2157, 2261, 2408, 2422, 2433, 2563, 2582, 2734, 2779, 3027, 3056, 3094, 3106, 3340, 3382, 3503, 3533, 3557, 3561, 3568, 3707, 3718, 3756, 3778, 3798, 4075, 4102, 4179, 4194, 4209, 4212, 4291, 4310, 4327, 4334, 4524, 4530, 4578, 4643, 4675, 4886, 5050, 5295, 5333, 5470], 'response': [24, 229, 269, 474, 3677, 3704, 3799], 'environmental': [26, 271, 512, 3708, 3911], 'and': [27, 105, 188, 272, 350, 433, 502, 538, 606, 683, 804, 812, 833, 905, 955, 975, 1025, 1044, 1153, 1253, 1325, 1496, 1553, 1560, 1713, 1910, 1942, 2021, 2061, 2074, 2097, 2118, 2166, 2264, 2300, 2304, 2311, 2339, 2342, 2346, 2380, 2411, 2473, 2517, 2588, 2641, 2825, 2836, 2874, 2924, 2935, 2965, 3013, 3084, 3251, 3544, 3615, 3662, 3712, 3787, 3808, 3831, 3881, 3901, 3937, 4005, 4082, 4203, 4211, 4232, 4304, 4354, 4374, 4424, 4443, 4552, 4652, 4724, 4895, 4952, 4959, 5112, 5309, 5341, 5420, 5460, 5473, 5496, 5517], 'physiological': [28, 273, 3710], 'signals.': [29, 274], 'This': [30, 85, 154, 224, 275, 330, 399, 469, 877, 1098, 2079, 2592, 3203, 3331, 3870, 4276, 4497, 5478], 'includes': [31, 276], 'strong': [32, 277, 3307, 3437], 'inhibition': [33, 278], 'via': [34, 279], 'catabolite': [35, 280, 582, 590, 666, 3981, 3989, 4065], 'repression,': [36, 281], 'elicited': [37, 282], 'by': [38, 283, 777, 837, 841, 1015, 1036, 1310, 1511, 1543, 1583, 1901, 2048, 2104, 2135, 2351, 2363, 2418, 2429, 2578, 2720, 2905, 2976, 3003, 3011, 3048, 3061, 3199, 4176, 4236, 4240, 4414, 4435, 4709, 4910, 4942, 4982, 5300, 5447, 5503], 'carbon': [40, 56, 241, 285, 301, 486, 581, 611, 1642, 3806, 3980, 4010, 5041], 'sources': [41, 242, 286, 487, 612, 4011], 'that': [42, 54, 72, 88, 149, 156, 172, 230, 287, 299, 317, 333, 394, 401, 417, 475, 497, 546, 675, 900, 917, 989, 1120, 1163, 1644, 1822, 1947, 2040, 2063, 2126, 2463, 2484, 2506, 2551, 2600, 2664, 2674, 2701, 2714, 2730, 2778, 2801, 2852, 2979, 3025, 3028, 3156, 3295, 3488, 3623, 3686, 3745, 3792, 3809, 3843, 3896, 3945, 4074, 4299, 4316, 4388, 4519, 4562, 5043, 5221, 5346, 5439, 5462], 'cells': [44, 289, 3095, 3679], 'prefer': [45, 290], 'hydrocarbons.': [47, 292], 'The': [48, 293, 894, 973, 1241, 1255, 1505, 1540, 1579, 1629, 1785, 2011, 2037, 2333, 2354, 2373, 2503, 2570, 2694, 2710, 2878, 2895, 2939, 2968, 3039, 3064, 3128, 3353, 3643, 3775, 3850, 4293, 4372, 4640, 4654, 4904, 4939, 4978, 5028, 5184, 5410, 5436], 'Crc': [49, 67, 89, 118, 157, 173, 181, 201, 294, 312, 334, 363, 402, 418, 426, 446, 1502, 1561, 1621, 1635, 1817, 1895, 1912, 1948, 2003, 2016, 2041, 2127, 2171, 2185, 2278, 2355, 2388, 2398, 2419, 2430, 2464, 2510, 2535, 2601, 2715, 2738, 2755, 2793, 2814, 2856, 2893, 2898, 2914, 2942, 2980, 3078, 3145, 3433, 3493, 3647, 3813, 3824, 4901, 4960, 5020, 5034, 5216, 5294, 5311, 5347, 5402, 5415, 5440], 'protein,': [50, 295], 'a': [51, 69, 226, 296, 314, 471, 493, 508, 580, 881, 1295, 1311, 1547, 1638, 1902, 1951, 2081, 2091, 2105, 2158, 2271, 2549, 2560, 2579, 2661, 2667, 2706, 3031, 3179, 3188, 3200, 3306, 3322, 3333, 3436, 3490, 3634, 3673, 3687, 3702, 3804, 3854, 3892, 3907, 3979, 4280, 4694, 4710, 4946, 5037, 5301, 5350, 5480, 5490, 5504], 'global': [52, 297, 562, 1483, 1639, 2027, 2087, 2275, 3961, 4882, 5038, 5426, 5486], 'regulator': [53, 298, 1640, 1790, 2028, 3129, 3159, 5039, 5189, 5427], 'controls': [55, 174, 300, 419, 1259, 4658], 'flow': [57, 302], 'pseudomonads,': [59, 304], 'has': [60, 82, 305, 327, 822, 879, 3090, 3690, 4221, 4278], 'an': [61, 306, 1155, 1819, 2647, 2783, 3498, 3681, 3715, 3785, 4554, 5218], 'important': [62, 307, 3552, 3716], 'role': [63, 308, 1787, 5186], 'this': [65, 81, 310, 326, 677, 763, 808, 1479, 1488, 1633, 1789, 2026, 3132, 3157, 3376, 3779, 4076, 4162, 4207, 4878, 4887, 5032, 5188, 5425], 'inhibition.': [66, 311], 'translational': [70, 315, 3158, 3185, 3695], 'repressor': [71, 316], 'regulates': [73, 318, 2128], 'genes,': [76, 321, 977, 2937, 3318, 3661, 4376], 'but': [77, 322, 2256, 2699, 3024, 3103, 3856], 'how': [78, 323, 886, 1620, 2085, 4285, 5019, 5484], 'it': [79, 324, 1617, 2142, 2546, 2597, 2727, 2774, 5016], 'does': [80, 325, 3037], 'remained': [83, 328], 'unknown.': [84, 329], 'study': [86, 331, 555, 3954], 'reports': [87, 332], 'binds': [90, 335, 1908, 5307], 'sites': [92, 120, 127, 151, 337, 365, 372, 396, 1825, 2357, 2973, 3143, 5224], 'located': [93, 338, 978, 1826, 2917, 3018, 4377, 5225], 'at': [94, 339, 617, 1165, 1171, 1827, 2137, 2191, 2258, 2320, 2358, 2483, 2676, 2697, 2703, 2760, 2765, 2845, 2918, 3137, 3146, 3794, 4016, 4564, 4570, 5226], 'translation': [96, 125, 184, 204, 341, 370, 429, 449, 1829, 1836, 2008, 2053, 2174, 2400, 2555, 2770, 2817, 2839, 2879, 2929, 2955, 3081, 3194, 3664, 5228, 5235, 5407, 5452], 'initiation': [97, 126, 342, 371, 1830, 2556, 2880, 2930, 2956, 5229], 'regions': [98, 343, 1831, 2881, 2931, 2957, 5230], 'mRNAs': [101, 346, 2334, 2360, 2831], 'coding': [102, 130, 347, 375, 896, 4295], 'XylR': [104, 187, 349, 432, 1040, 1138, 1256, 1320, 1592, 2403, 2568, 2574, 2603, 2732, 2819, 2873, 3053, 3629, 3830, 4439, 4537, 4655, 4719, 4991], 'XylS,': [106, 351], 'two': [107, 140, 178, 352, 385, 423, 1106, 1249, 2138, 2148, 2532, 2638, 2829, 3007, 3016, 3326, 3817, 4505, 4648], 'specific': [108, 206, 353, 451, 986, 1824, 4385, 5223], 'transcription': [109, 194, 354, 439, 1007, 1028, 1152, 1595, 2469, 2529, 2618, 4406, 4427, 4551, 4994], 'activators': [110, 355, 2150], 'genes.': [114, 199, 359, 444, 995, 1628, 2036, 2967, 3774, 4394, 5027, 5435], 'Unexpectedly,': [115, 360], 'eight': [116, 361, 2883], 'additional': [117, 362, 3786], 'binding': [119, 364, 2356, 2753, 3308], 'were': [121, 366, 2187, 2916, 3329, 3760], 'found': [122, 367, 2188], 'overlapping': [123, 368, 2927, 2953], 'several': [132, 377, 614, 3253, 4013], 'enzymes': [133, 378, 899, 3008, 3670, 4298], 'pathway,': [136, 211, 381, 456, 2153, 3346], 'all': [137, 196, 382, 441], 'encoded': [138, 383, 3010, 3371], 'within': [139, 166, 384, 411, 2949, 3168], 'polycistronic': [141, 167, 386, 412, 2168, 2266, 2951, 3022, 3147, 3169, 3201], 'mRNAs.': [142, 168, 387, 413, 2169, 2267, 2591], 'Evidence': [143, 388], 'provided': [145, 390], 'supporting': [146, 391], 'idea': [148, 393], 'these': [150, 395, 576, 1260, 2019, 2046, 2359, 2390, 2531, 2901, 2913, 2950, 2971, 3848, 3975, 4659, 5418, 5445], 'are': [152, 397, 615, 686, 694, 791, 890, 909, 926, 1783, 1899, 2318, 2349, 2361, 2420, 2431, 2739, 3009, 3821, 3868, 4014, 4085, 4093, 4190, 4289, 4308, 4325, 5182, 5298], 'functional.': [153, 398], 'implies': [155, 400, 3155], 'can': [158, 403, 1102, 1121, 2017, 2094, 2593, 2634, 2723, 3045, 3160, 3358, 3525, 4501, 4520, 5416, 5493], 'differentially': [159, 404, 3161], 'modulate': [160, 405, 3162], 'particular': [164, 409, 826, 4225], 'It': [169, 414], 'proposed': [171, 416, 2777], 'ways.': [179, 424], 'First,': [180, 425, 2141], 'inhibits': [182, 202, 427, 447, 1622, 1645, 2143, 2172, 5021, 5044], 'XylS': [189, 434, 1021, 1118, 1167, 2630, 2875, 3832, 4420, 4517, 4566], 'regulators,': [190, 435], 'thereby': [191, 436, 3632], 'reducing': [192, 437, 2868, 3648], 'Second,': [200, 445, 2170], 'structural': [207, 452, 2066, 2178, 2292, 2884, 5465], 'acting': [212, 457, 1016, 2136, 4415], 'mainly': [213, 458, 1516, 2657, 4915], 'on': [214, 459, 817, 828, 1508, 1517, 1550, 1557, 1938, 2029, 2279, 2389, 2399, 2511, 2540, 2625, 2794, 2815, 2837, 2857, 2993, 3019, 3079, 3440, 3637, 3811, 4216, 4227, 4907, 4916, 4949, 4956, 5337, 5428], 'proteins': [215, 238, 460, 483, 2069, 2406, 3212, 5468], 'involved': [216, 461, 1650, 2070, 2407, 3339, 3502, 5049, 5469], 'first': [219, 464, 3153, 3342], 'steps': [220, 465, 3343], 'toluene': [222, 467, 832, 902, 1135, 2409, 3357, 4231, 4301, 4534], 'assimilation.': [223, 468, 2412], 'ensures': [225, 470], 'rapid': [227, 472, 3703], 'inhibitory': [228, 473], 'reduces': [231, 476, 2602, 2716, 3058, 3825], 'degradation': [237, 482], 'when': [239, 484, 613, 779, 1294, 1780, 3531, 3553, 3865, 4012, 4178, 4693, 5179], 'preferred': [240, 485, 690, 1286, 1781, 3688, 3805, 3866, 4089, 4685, 5180], 'become': [243, 488, 880, 3550, 3691, 4279], 'available.': [244, 489, 3692], 'IntroductionPseudomonas': [490, 3889], 'putida': [491, 769, 797, 844, 3890, 4168, 4196, 4243], 'ubiquitous': [494, 3893], 'soil': [495, 3894], 'bacterium': [496, 809, 3895, 4208], 'shows': [498, 674, 3897, 4073], 'great': [499, 3898], 'metabolic': [500, 2116, 3899, 5515], 'versatility': [501, 3900], 'ability': [504, 540, 1590, 2896, 3903, 3939, 4989], 'live': [506, 3905], 'under': [507, 3097, 3906], 'wide': [509, 3908], 'range': [510, 3909], 'conditions': [513, 3711, 3912], '(1Dos': [514, 3913], 'Santos': [515, 3914], 'V.A.': [516, 3915], 'Heim': [517, 3916], 'S.': [518, 959, 1064, 1187, 1203, 1219, 1263, 1335, 1364, 1384, 1400, 1435, 1528, 1567, 1604, 1872, 1959, 2221, 2491, 2683, 3111, 3394, 3511, 3917, 4358, 4463, 4586, 4602, 4618, 4662, 4734, 4763, 4783, 4799, 4834, 4927, 4966, 5003, 5271, 5358], 'Moore': [519, 3918], 'E.R.': [520, 3919], 'Strätz': [521, 3920], 'M.': [522, 746, 1333, 1350, 1457, 1735, 1801, 3216, 3239, 3727, 3921, 4145, 4732, 4749, 4856, 5134, 5200], 'Timmis': [523, 960, 1086, 1351, 1389, 1403, 3922, 4359, 4485, 4750, 4788, 4802], 'K.N.': [524, 961, 1087, 1352, 1390, 1404, 3923, 4360, 4486, 4751, 4789, 4803], 'Environ.': [525, 867, 945, 1444, 1530, 1569, 1606, 2493, 3120, 3924, 4266, 4344, 4843, 4929, 4968, 5005], 'Microbiol.': [526, 630, 643, 655, 868, 946, 964, 1089, 1423, 1445, 1531, 1570, 1607, 1846, 2494, 3121, 3591, 3925, 4029, 4042, 4054, 4267, 4345, 4363, 4488, 4822, 4844, 4930, 4969, 5006, 5245], '2004;': [527, 735, 1206, 1690, 2686, 3463, 3926, 4134, 4605, 5089], '6:': [528, 632, 3927, 4031], '1264-1286Crossref': [529, 3928], 'PubMed': [530, 634, 647, 716, 738, 757, 856, 872, 950, 968, 1077, 1093, 1195, 1209, 1236, 1273, 1341, 1358, 1378, 1396, 1412, 1427, 1449, 1465, 1535, 1574, 1611, 1671, 1693, 1708, 1727, 1746, 1775, 1812, 1850, 1864, 1883, 1927, 1970, 1989, 2213, 2232, 2251, 2498, 2689, 3125, 3225, 3246, 3272, 3287, 3411, 3427, 3466, 3480, 3517, 3580, 3598, 3738, 3929, 4033, 4046, 4115, 4137, 4156, 4255, 4271, 4349, 4367, 4476, 4492, 4594, 4608, 4635, 4672, 4740, 4757, 4777, 4795, 4811, 4826, 4848, 4864, 4934, 4973, 5010, 5070, 5092, 5107, 5126, 5145, 5174, 5211, 5249, 5263, 5282, 5326, 5369, 5388], 'Scopus': [531, 635, 648, 717, 739, 758, 873, 951, 969, 1078, 1094, 1210, 1237, 1428, 1466, 1536, 1575, 1612, 1694, 1709, 1728, 1747, 1776, 1813, 1851, 1865, 1884, 1928, 1971, 1990, 2214, 2233, 2252, 2499, 2690, 3226, 3247, 3273, 3288, 3412, 3428, 3467, 3481, 3518, 3599, 3739, 3930, 4034, 4047, 4116, 4138, 4157, 4272, 4350, 4368, 4477, 4493, 4609, 4636, 4827, 4865, 4935, 4974, 5011, 5093, 5108, 5127, 5146, 5175, 5212, 5250, 5264, 5283, 5327, 5370, 5389], '(207)': [532, 3931], 'Google': [533, 637, 650, 662, 719, 741, 760, 857, 875, 953, 971, 1080, 1096, 1196, 1212, 1239, 1274, 1342, 1359, 1379, 1397, 1413, 1430, 1450, 1468, 1538, 1577, 1614, 1672, 1696, 1711, 1730, 1749, 1778, 1815, 1853, 1867, 1886, 1930, 1973, 1992, 2216, 2235, 2254, 2501, 2692, 3126, 3228, 3249, 3275, 3290, 3414, 3430, 3469, 3483, 3520, 3581, 3601, 3741, 3932, 4036, 4049, 4061, 4118, 4140, 4159, 4256, 4274, 4352, 4370, 4479, 4495, 4595, 4611, 4638, 4673, 4741, 4758, 4778, 4796, 4812, 4829, 4849, 4867, 4937, 4976, 5013, 5071, 5095, 5110, 5129, 5148, 5177, 5214, 5252, 5266, 5285, 5329, 5372, 5391], 'Scholar).': [534, 663, 761, 876, 972, 1097, 1240, 1469, 1539, 1578, 1615, 1816, 1887, 1931, 1993, 2502, 2693, 3127, 3431, 3521, 3602, 3933, 4062, 4160, 4275, 4371, 4496, 4639, 4868, 4938, 4977, 5014, 5215, 5286, 5330, 5392], 'Its': [535, 3934], 'biotechnological': [536, 3935], 'potential': [537, 766, 3936, 4165], 'its': [539, 557, 3001, 3882, 3938, 3956], 'degrade': [542, 771, 3941, 4170], 'many': [543, 3942], 'aromatic': [544, 772, 784, 888, 1674, 2077, 3523, 3555, 3621, 3682, 3943, 4171, 4183, 4287, 5073, 5476], 'compounds': [545, 790, 889, 1287, 1675, 3524, 3622, 3867, 3944, 4189, 4288, 4686, 5074], 'generate': [547, 3946], 'pollution': [548, 3947], 'problems': [549, 3948], 'have': [550, 1945, 3753, 3949, 5344], 'led': [551, 3950], 'detailed': [554, 3953], 'metabolism.': [558, 3957], 'A': [559, 3958], 'number': [560, 3959], 'networks': [564, 2089, 3963, 5488], 'carefully': [565, 3964], 'control': [566, 2098, 3133, 3746, 3965, 5497], 'numerous': [568, 3967], 'catabolic': [569, 3181, 3968], 'pathways': [570, 3969], 'P.': [572, 768, 796, 843, 1215, 1524, 1874, 1961, 2223, 3266, 3390, 3725, 3971, 4167, 4195, 4242, 4614, 4923, 5273, 5360], 'putida.': [573, 3972], 'Some': [574, 3183, 3973], 'regulatory': [577, 1503, 2297, 2876, 3743, 3976, 4902], 'systems': [578, 1485, 3540, 3977, 4884], 'orchestrate': [579, 3978], 'repression': [583, 667, 1506, 1541, 3639, 3982, 4066, 4905, 4940], '(CCR)': [584, 3983], '3The': [585, 3984], 'abbreviations': [586, 3985], 'used': [587, 3986], 'are:': [588, 3987], 'CCRcarbon': [589, 3988], 'repression3MBA3-methylbenzyl': [591, 3990], 'alcoholBADHbenzyl': [592, 3991], 'alcohol': [593, 3992], 'dehydrogenaseBZDHbenzaldehyde': [594, 3993], 'dehydrogenaseC23Ocatechol-2,3-dioxygenaseTOL': [595, 3994], 'pathwaytoluene/xylene': [596, 3995], 'pathwayntnucleotide(s)PTSNtrnitrogen': [598, 3997], 'phosphotransferase': [599, 3998], 'system.': [600, 3999], 'process,': [601, 4000], 'which': [602, 1148, 1907, 2154, 2527, 2633, 2722, 2826, 3055, 3328, 3496, 4001, 4547, 5306], 'allows': [603, 4002], 'sequential': [605, 4004], 'hierarchical': [607, 4006], 'different': [610, 2139, 4009], 'available': [616, 4015], 'non-growth-limiting': [618, 4017], 'concentrations': [619, 4018], '(for': [620, 4019], 'reviews,': [621, 4020], 'see': [622, 4021], 'Refs.': [623, 936, 4022, 4335], '2Görke': [624, 4023], 'B.': [625, 1437, 1455, 3113, 4024, 4836, 4854], 'Stülke': [626, 4025], 'J.': [627, 640, 711, 733, 851, 1190, 1204, 1225, 1268, 1336, 1353, 1373, 1391, 1407, 1421, 1666, 1688, 1703, 1722, 1754, 1770, 1859, 2208, 2684, 3240, 3280, 3400, 3422, 3461, 3475, 3509, 3512, 3575, 4026, 4039, 4110, 4132, 4250, 4589, 4603, 4624, 4667, 4735, 4752, 4772, 4790, 4806, 4820, 5065, 5087, 5102, 5121, 5153, 5169, 5258], 'Nat.': [628, 4027], 'Rev.': [629, 656, 963, 3594, 4028, 4055, 4362], '2008;': [631, 644, 1861, 2210, 3477, 4030, 4043, 5260], '613-624Crossref': [633, 4032], '(1063)': [636, 4035], 'Scholar,': [638, 651, 720, 742, 858, 1081, 1197, 1213, 1343, 1360, 1380, 1398, 1414, 1431, 1451, 1731, 1750, 1854, 1868, 1974, 2217, 2236, 3229, 3276, 3415, 3470, 3582, 4037, 4050, 4119, 4141, 4257, 4480, 4596, 4612, 4742, 4759, 4779, 4797, 4813, 4830, 4850, 5130, 5149, 5253, 5267, 5373], '3Deutscher': [639, 4038], 'Curr.': [641, 4040], 'Opin.': [642, 4041], '11:': [645, 4044], '87-93Crossref': [646, 4045], '(443)': [649, 4048], '4Rojo': [652, 4051], 'F.': [653, 732, 752, 1687, 1702, 1741, 1756, 1807, 1844, 1858, 1876, 1963, 2207, 2225, 3460, 3474, 4052, 4131, 4151, 5086, 5101, 5140, 5155, 5206, 5243, 5257, 5275, 5362], 'FEMS': [654, 4053], '2010;': [657, 4056], '(DOI:': [658, 4057], '10.1111/j.1574–6976.2010.00218.x': [659, 4058], 'March': [660, 4059], '10)PubMed': [661, 4060], 'Pseudomonas,': [665, 4064], 'not': [669, 2189, 2426, 2700, 2865, 3135, 3857, 4068], 'well': [670, 4069], 'understood.': [671, 4070], 'Available': [672, 4071], 'evidence': [673, 2850, 4072], 'bacterial': [678, 1796, 3528, 4077, 5195], 'group,': [679, 4078], 'certain': [680, 1655, 3166, 4079, 5054], 'organic': [681, 4080], 'acids': [682, 685, 1715, 4081, 4084, 5114], 'amino': [684, 1714, 4083, 5113], 'most': [688, 4087], 'strongly': [689, 4088], 'compounds,': [691, 4090], 'whereas': [692, 915, 2424, 2990, 3312, 4091, 4314], 'hydrocarbons': [693, 773, 821, 1698, 4092, 4172, 4220, 5097], 'less': [695, 4094], 'preferred;': [696, 4095], 'preference': [698, 4097], 'glucose': [700, 1292, 1514, 4099, 4691, 4913], 'lies': [701, 4100], 'somewhere': [702, 4101], 'between': [704, 4103], '(5Hester': [705, 1716, 4104, 5115], 'K.L.': [706, 1717, 1752, 4105, 5116, 5151], 'Madhusudhan': [707, 1718, 4106, 5117], 'K.T.': [708, 1719, 4107, 5118], 'Sokatch': [709, 1720, 1768, 4108, 5119, 5167], 'J.R.': [710, 1721, 1769, 4109, 5120, 5168], 'Bacteriol.': [712, 734, 852, 1191, 1205, 1269, 1337, 1354, 1374, 1392, 1408, 1667, 1689, 1704, 1723, 1771, 1860, 2209, 2685, 3423, 3462, 3476, 3513, 3576, 4111, 4133, 4251, 4590, 4604, 4668, 4736, 4753, 4773, 4791, 4807, 5066, 5088, 5103, 5122, 5170, 5259], '2000;': [713, 1724, 1772, 3424, 4112, 5123, 5171], '182:': [714, 1725, 1773, 3425, 4113, 5124, 5172], '1150-1153Crossref': [715, 1726, 4114, 5125], '(41)': [718, 1729, 4117, 5128], '6Morales': [721, 4120], 'G.': [722, 1677, 3450, 4121, 5076], 'Linares': [723, 1678, 3451, 4122, 5077], 'J.F.': [724, 1679, 3452, 4123, 5078], 'Beloso': [725, 1680, 3453, 4124, 5079], 'A.': [726, 860, 938, 1066, 1265, 1382, 1402, 1681, 1840, 3454, 3586, 4125, 4259, 4337, 4465, 4664, 4781, 4801, 5080, 5239], 'Albar': [727, 1682, 3455, 4126, 5081], 'J.P.': [728, 1683, 3456, 4127, 5082], 'Martínez': [729, 1684, 3457, 4128, 5083], 'J.L.': [730, 957, 1083, 1189, 1201, 1221, 1369, 1406, 1439, 1526, 1565, 1602, 1685, 2489, 2681, 3115, 3396, 3458, 3590, 4129, 4356, 4482, 4588, 4600, 4620, 4768, 4805, 4838, 4925, 4964, 5001, 5084], 'Rojo': [731, 751, 1686, 1701, 1740, 1806, 1843, 1857, 1875, 1962, 2206, 2224, 3459, 3473, 4130, 4150, 5085, 5100, 5139, 5205, 5242, 5256, 5274, 5361], '186:': [736, 1207, 1691, 2687, 3464, 4135, 4606, 5090], '1337-1344Crossref': [737, 1692, 3465, 4136, 5091], '(100)': [740, 1695, 3468, 4139, 5094], '7Moreno': [743, 1732, 4142, 5131], 'R.': [744, 1733, 1799, 1838, 1856, 1870, 1957, 2205, 2219, 3472, 4143, 5132, 5198, 5237, 5255, 5269, 5356], 'Martínez-Gomariz': [745, 1734, 1800, 4144, 5133, 5199], 'Yuste': [747, 1736, 1802, 1841, 4146, 5135, 5201, 5240], 'L.': [748, 862, 940, 1700, 1737, 1758, 1803, 1842, 1916, 1978, 2240, 3237, 4147, 4261, 4339, 5099, 5136, 5157, 5202, 5241, 5315, 5377], 'Gil': [749, 1738, 1804, 4148, 5137, 5203], 'C.': [750, 1367, 1739, 1805, 3262, 4149, 4766, 5138, 5204], 'Proteomics.': [753, 1742, 1808, 4152, 5141, 5207], '2009;': [754, 1743, 1809, 1880, 1924, 1967, 1986, 2229, 2248, 4153, 5142, 5208, 5279, 5323, 5366, 5385], '9:': [755, 1744, 1810, 4154, 5143, 5209], '2910-2928Crossref': [756, 1745, 1811, 4155, 5144, 5210], '(81)': [759, 1748, 1814, 4158, 5147, 5213], 'For': [762, 4161], 'reason,': [764, 4163], 'frequently': [775, 4174], 'compromised': [776, 4175], 'CCR': [778, 794, 815, 1312, 1489, 4177, 4193, 4214, 4711, 4888], 'addition': [781, 1277, 4180, 4676], 'substrates,': [785, 1281, 3654, 4184, 4680], 'other': [786, 1498, 2201, 2940, 3184, 4185, 4897], 'more': [787, 1160, 2671, 2834, 4186, 4559], 'readily': [788, 4187], 'degradable': [789, 4188], 'present.': [792, 1784, 3869, 4191, 5183], 'Understanding': [793, 4192], 'may': [798, 4197], 'help': [799, 4198], 'improve': [801, 4200], 'biodegradation': [802, 4201], 'rates': [803, 4202], 'usefulness': [806, 4205], 'biotechnology': [811, 4210], 'bioremediation.The': [814, 4213], 'imposed': [816, 4215], 'been': [823, 3092, 3754, 4222], 'studied': [824, 3755, 4223], 'with': [825, 1038, 1588, 2051, 2062, 2096, 2908, 4224, 4437, 4987, 5450, 5461, 5495], 'emphasis': [827, 4226], 'xylene': [834, 2437, 3504, 4233], 'specified': [836, 4235], 'carried': [840, 2103, 3198, 4239, 5502], '(8Williams': [847, 4246], 'P.A.': [848, 864, 942, 4247, 4263, 4341], 'Murray': [849, 4248], 'K.': [850, 3264, 4249], '1974;': [853, 4252], '120:': [854, 4253], '416-423Crossref': [855, 4254], '9Greated': [859, 937, 4258, 4336], 'Lambertsen': [861, 939, 4260, 4338], 'Williams': [863, 941, 4262, 4340], 'Thomas': [865, 943, 4264, 4342], 'C.M.': [866, 944, 4265, 4343], '2002;': [869, 947, 3269, 4268, 4346], '4:': [870, 948, 4269, 4347], '856-871Crossref': [871, 949, 4270, 4348], '(159)': [874, 952, 4273, 4351], 'model': [882, 4281], 'system': [883, 1520, 1581, 4282, 4919, 4980], 'understand': [885, 4284], 'recalcitrant': [887, 4286], 'biodegraded': [891, 4290], 'nature.': [893, 4292], 'transform': [901, 4300], 'into': [903, 907, 922, 1059, 3351, 3886, 4302, 4306, 4321, 4458], 'benzoate': [904, 919, 1060, 3354, 3372, 3448, 4303, 4318, 4459], 'xylenes': [906, 1026, 1045, 4305, 4425, 4444], 'methylbenzoates': [908, 921, 1062, 4307, 4320, 4461], 'clustered': [910, 4309], '"upper': [913, 4312], 'operon,"': [914, 4313], 'those': [916, 2425, 2606, 3348, 4315], 'convert': [918, 4317], 'or': [920, 997, 1061, 1136, 1291, 1293, 1513, 1586, 2368, 2414, 3100, 3367, 3709, 4319, 4396, 4460, 4535, 4690, 4692, 4912, 4985], 'Krebs': [923, 4322], 'cycle': [924, 4323], 'intermediates': [925, 4324], 'grouped': [927, 4326], '"meta': [930, 4329], 'operon"': [931, 4330], '(Fig.': [932, 4331], '1)': [933, 4332], '(reviewed': [934, 4333], 'Scholar': [954, 4353], '10Ramos': [956, 4355], 'Marqués': [958, 1186, 1202, 1218, 1363, 1383, 1434, 1527, 1566, 1603, 2490, 2682, 3110, 3393, 4357, 4585, 4601, 4617, 4762, 4782, 4833, 4926, 4965, 5002], 'Annu.': [962, 4361], '1997;': [965, 1462, 3577, 4364, 4861], '51:': [966, 4365], '341-373Crossref': [967, 4366], '(269)': [970, 4369], 'xylR': [974, 1242, 2301, 2347, 2544, 2554, 3083, 4373, 4641], 'xylS': [976, 1101, 1143, 1151, 2299, 2345, 2654, 2717, 2762, 2822, 2830, 2842, 4375, 4500, 4542, 4550], 'downstream': [979, 4378], 'meta': [982, 1003, 1010, 1051, 1473, 2167, 2265, 2340, 2589, 2621, 2805, 2925, 3316, 3364, 4381, 4402, 4409, 4450, 4872], 'operon,': [983, 4382], 'encode': [984, 4383], 'transcriptional': [987, 1022, 1041, 2056, 2149, 2631, 3630, 3656, 3769, 3833, 4386, 4421, 4440, 5455], 'regulators': [988, 2057, 3186, 3834, 4387, 5456], 'activate': [990, 1122, 1176, 1594, 4389, 4521, 4575, 4993], 'Benzoate': [996, 4395], 'methylbenzoates,': [998, 4397], 'substrates': [1000, 1782, 3388, 3842, 4399, 5181], 'enzymes,': [1005, 4404], 'induce': [1006, 1027, 1047, 4405, 4426, 4446], 'operon': [1011, 1032, 1052, 2806, 3304, 3317, 4410, 4431, 4451], 'from': [1012, 1033, 1105, 1144, 1248, 1596, 2393, 2530, 2637, 2658, 3073, 3356, 4411, 4432, 4504, 4543, 4647, 4995], 'promoter': [1013, 1034, 1597, 2659, 2663, 2846, 4412, 4433, 4996], 'Pm': [1014, 1123, 1177, 4413, 4522, 4576], 'as': [1017, 1289, 2198, 2652, 2788, 3565, 3625, 3845, 4416, 4688], 'effectors': [1018, 1183, 3626, 3846, 4417, 4582], 'activator.': [1023, 1042, 2404, 4422, 4441], 'Toluene': [1024, 1043, 4423, 4442], 'upper': [1031, 2165, 2263, 2338, 2587, 2648, 2784, 2923, 3303, 3386, 4430], 'Pu': [1035, 1324, 1509, 1552, 1598, 2472, 2516, 2614, 3059, 4434, 4723, 4908, 4951, 4997], 'interacting': [1037, 4436], 'also': [1046, 1476, 2257, 3380, 3434, 4445, 4875], 'without': [1053, 4452], 'need': [1055, 4454], 'their': [1057, 2007, 4456, 5406], 'conversion': [1058, 4457], '(11Inouye': [1063, 4462], 'Nakazawa': [1065, 1067, 1264, 1266, 4464, 4466, 4663, 4665], 'T.': [1068, 1267, 1331, 3258, 3260, 4467, 4666, 4730], 'Proc.': [1069, 1919, 1981, 2243, 3217, 4468, 5318, 5380], 'Natl.': [1070, 1920, 1982, 2244, 3218, 4469, 5319, 5381], 'Acad.': [1071, 1921, 1983, 2245, 3219, 4470, 5320, 5382], 'Sci.': [1072, 1922, 1984, 2246, 3220, 4471, 5321, 5383], 'U.S.A.': [1073, 1923, 1985, 2247, 3221, 4472, 5322, 5384], '1987;': [1074, 1090, 4473, 4489], '84:': [1075, 4474], '5182-5186Crossref': [1076, 4475], '(82)': [1079, 4478], '12Ramos': [1082, 4481], 'Mermod': [1084, 4483], 'N.': [1085, 1329, 4484, 4728], 'Mol.': [1088, 1422, 1845, 3241, 3592, 4487, 4821, 5244], '1:': [1091, 4490], '293-300Crossref': [1092, 4491], '(75)': [1095, 4494], 'occurs': [1099, 3567, 3793, 4498], 'because': [1100, 3375, 3823, 4499], 'be': [1103, 2481, 2594, 2635, 2724, 2833, 3046, 3359, 4502], 'transcribed': [1104, 2656, 4503], 'promoters.': [1107, 2533, 4506], 'Promoter': [1108, 4507], 'PS2': [1109, 2677, 4508], 'provides': [1110, 2270, 2849, 4509], 'low': [1112, 3562, 4511], 'level': [1113, 2162, 3797, 4512], 'constitutive': [1114, 4513], 'expression,': [1115, 4514], 'allowing': [1116, 4515], 'levels': [1119, 1172, 1892, 2542, 2565, 2575, 2584, 2604, 2719, 2733, 2797, 2824, 2870, 3070, 3174, 3605, 3827, 4518, 4571, 5291], 'only': [1124, 2190, 2998, 3319, 4523], 'presence': [1127, 1133, 2645, 2736, 2781, 3140, 3384, 3783, 3802, 4526, 4532], 'effectors.': [1129, 4528], 'However,': [1130, 1616, 3432, 4529, 5015], 'xylene,': [1137, 4536], 'activates': [1139, 2528, 4538], 'another': [1145, 4544], 'promoter,': [1146, 4545], 'PS1,': [1147, 2308, 2660, 2698, 4546], 'considerably': [1149, 4548], 'increases': [1150, 4549], 'generates': [1154, 4553], 'mRNA': [1156, 2718, 2763, 2796, 2823, 2843, 3023, 4555], 'translated': [1157, 2669, 4556], '10': [1158, 4557], 'times': [1159, 2160, 4558], 'efficiently': [1161, 2672, 4560], 'than': [1162, 2673, 4561], 'originating': [1164, 2675, 2696, 2702, 2764, 2844, 4563], 'PS2.': [1166, 2642, 4565], 'then': [1169, 4568], 'synthesized': [1170, 4569], 'high': [1173, 3534, 3537, 4572], 'enough': [1174, 4573], 'even': [1178, 4577], 'absence': [1181, 4580], '(13Gallegos': [1184, 4583], 'M.T.': [1185, 4584], 'Ramos': [1188, 1200, 1220, 1368, 1405, 1438, 1525, 1564, 1601, 2488, 2680, 3114, 3395, 4587, 4599, 4619, 4767, 4804, 4837, 4924, 4963, 5000], '1996;': [1192, 1424, 1446, 3122, 4591, 4823, 4845], '178:': [1193, 4592], '2356-2361Crossref': [1194, 4593], '14González-Pérez': [1198, 4597], 'M.M.': [1199, 2679, 4598], '1898-1901Crossref': [1208, 2688, 4607], '(19)': [1211, 2691, 4610], '15Domínguez-Cuevas': [1214, 4613], 'González-Pastor': [1216, 3391, 4615], 'J.E.': [1217, 3392, 4616], 'de': [1222, 1365, 1417, 3397, 4621, 4764, 4816], 'Lorenzo': [1223, 1345, 1418, 3398, 4622, 4744, 4817], 'V.': [1224, 1346, 1419, 3399, 4623, 4745, 4818], 'Biol.': [1226, 3242, 3401, 3593, 4625], 'Chem.': [1227, 3402, 4626], '2006;': [1228, 1532, 3403, 4627, 4931], '281:': [1229, 3404, 4628], '11981-11991Abstract': [1230, 3405, 4629], 'Full': [1231, 1233, 3406, 3408, 3733, 3735, 4630, 4632], 'Text': [1232, 1234, 3407, 3409, 3734, 3736, 4631, 4633], 'PDF': [1235, 3410, 3737, 4634], '(160)': [1238, 3413, 4637], 'gene,': [1243, 4642], 'turn,': [1245, 4644], 'expressed': [1247, 2636, 4646], 'contiguous': [1250, 4649], 'promoters,': [1251, 2391, 2475, 2639, 4650], 'PR1': [1252, 4651], 'PR2.': [1254, 4653], 'protein': [1257, 1636, 1821, 3501, 4656, 5035, 5220], 'negatively': [1258, 4657], 'promoters': [1261, 1327, 1555, 2313, 2377, 2519, 4660, 4726, 4954], '(16Inouye': [1262, 4661], '1985;': [1270, 4669], '163:': [1271, 4670], '863-869Crossref': [1272, 4671], 'Scholar).When': [1275, 4674], 'growth': [1283, 4682], 'medium': [1284, 1297, 1549, 1940, 4683, 4696, 4948, 5339], 'contains': [1285, 2705, 3030, 4684], 'such': [1288, 2651, 2787, 4687], 'succinate': [1290, 1512, 3105, 4689, 4911], 'complete': [1296, 1548, 4695, 4947], 'used,': [1299, 4698], 'induction': [1301, 1624, 2611, 2745, 4700, 5023], '(TOL)': [1306, 4705], 'inhibited': [1309, 4708], 'phenomenon.': [1313, 4712], 'Repression': [1314, 1470, 4713, 4869], 'primarily': [1316, 4715], 'directed': [1317, 3761, 4716], 'reduce': [1319, 2768, 3000, 4718], 'activation': [1321, 3657, 4720], 'PS1': [1326, 1554, 2381, 2474, 2518, 2640, 2748, 2766, 4725, 4953], '(17Hugouvieux-Cotte-Pattat': [1328, 4727], 'Köhler': [1330, 4729], 'Rekik': [1332, 4731], 'Harayama': [1334, 3510, 4733], '1990;': [1338, 4737], '172:': [1339, 4738], '6651-6660Crossref': [1340, 4739], '18de': [1344, 4743], 'Cases': [1347, 4746], 'I.': [1348, 1386, 1416, 1522, 1563, 1600, 2487, 4747, 4785, 4815, 4921, 4962, 4999], 'Herrero': [1349, 4748], '1993;': [1355, 4754], '175:': [1356, 4755], '6902-6907Crossref': [1357, 4756], '19Duetz': [1361, 4760], 'W.A.': [1362, 1433, 1453, 3109, 4761, 4832, 4852], 'Jong': [1366, 4765], 'van': [1370, 1440, 1458, 3116, 4769, 4839, 4857], 'Andel': [1371, 1441, 1459, 3117, 4770, 4840, 4858], 'J.G.': [1372, 1442, 1460, 3118, 4771, 4841, 4859], '1994;': [1375, 1393, 1409, 4774, 4792, 4808], '176:': [1376, 1394, 1410, 4775, 4793, 4809], '2354-2361Crossref': [1377, 4776], '20Holtel': [1381, 4780], 'Möhler': [1385, 4784], 'Jakubzik': [1387, 4786], 'U.': [1388, 4787], '1773-1776Crossref': [1395, 4794], '21Marqués': [1399, 4798], 'Holtel': [1401, 4800], '2517-2524Crossref': [1411, 4810], '22Cases': [1415, 4814], 'Pérez-Martín': [1420, 4819], '19:': [1425, 3731, 4824], '7-17Crossref': [1426, 4825], '(80)': [1429, 4828], '23Duetz': [1432, 4831], 'Wind': [1436, 1454, 3112, 4835, 4853], 'Appl.': [1443, 1529, 1568, 1605, 2492, 3119, 4842, 4928, 4967, 5004], '62:': [1447, 3123, 4846], '601-606Crossref': [1448, 3124, 4847], '24Duetz': [1452, 4851], 'Kamp': [1456, 4855], 'Microbiology.': [1461, 4860], '143:': [1463, 4862], '2331-2338Crossref': [1464, 4863], '(20)': [1467, 4866], 'occurs,': [1477, 4876], 'although': [1478, 2476, 3035, 4877], 'milder.': [1481, 4880], 'Two': [1482, 2911, 4881], 'participate': [1486, 4885], 'effect.': [1490, 4889], 'One': [1491, 4890], 'involves': [1492, 1500, 4891, 4899], 'PTSNtr': [1494, 1519, 1559, 1580, 4893, 4918, 4958, 4979], 'proteins,': [1495, 4894], 'one': [1499, 4898], 'protein.': [1504, 2569, 2910, 3814, 4903], 'exerted': [1507, 4906], 'activity': [1510, 2513, 2983, 3002, 3044, 3060, 4909], 'depends': [1515, 1556, 2624, 3810, 4914, 4955], '(25Aranda-Olmedo': [1521, 4920], 'Marín': [1523, 4922], '72:': [1533, 4932], '7418-7421Crossref': [1534, 4933], '(32)': [1537, 4936], 'induced': [1542, 3381, 4941], 'components': [1545, 4944], 'both': [1558, 4957], '(26Aranda-Olmedo': [1562, 1599, 2486, 4961, 4998], '2005;': [1571, 1608, 2495, 4970, 5007], '71:': [1572, 1609, 2496, 4971, 5008], '4191-4198Crossref': [1573, 1610, 2497, 4972, 5009], '(64)': [1576, 1613, 2500, 4975, 5012], 'acts': [1582, 4981], 'interfering,': [1584, 4983], 'directly': [1585, 2049, 2416, 2427, 4984, 5448], 'indirectly,': [1587, 4986], 'unclear': [1619, 5018], 'present': [1630, 2012, 2123, 2711, 2759, 3532, 3560, 5029, 5411], 'work': [1631, 2013, 2848, 3780, 5030, 5412], 'addresses': [1632, 5031], 'issue.The': [1634, 5033], 'metabolism': [1643, 5042], 'sugars': [1656, 5055], '(27MacGregor': [1657, 5056], 'C.H.': [1658, 1762, 5057, 5161], 'Wolff': [1659, 5058], 'J.A.': [1660, 5059], 'Arora': [1661, 5060], 'S.K.': [1662, 5061], 'Phibbs': [1663, 1765, 5062, 5164], 'Jr.,': [1664, 1766, 5063, 5165], 'P.V.': [1665, 1767, 5064, 5166], '1991;': [1668, 5067], '173:': [1669, 5068], '7204-7212Crossref': [1670, 5069], 'Scholar),': [1673, 1697, 1712, 2255, 5072, 5096, 5111], '(6Morales': [1676, 3449, 5075], '(28Yuste': [1699, 5098], '2001;': [1705, 3514, 3595, 5104], '183:': [1706, 3515, 5105], '6197-6206Crossref': [1707, 5106], '(67)': [1710, 5109], '29Hester': [1751, 5150], 'Lehman': [1753, 5152], 'Najar': [1755, 5154], 'Song': [1757, 5156], 'Roe': [1759, 5158], 'B.A.': [1760, 5159], 'MacGregor': [1761, 5160], 'Hager': [1763, 5162], 'P.W.': [1764, 5163], '1144-1149Crossref': [1774, 5173], '(86)': [1777, 5176], 'Scholar)': [1779, 3250, 5178], 'final': [1786, 2109, 3851, 5185, 5508], 'optimize': [1793, 5192], 'metabolism,': [1794, 5193], 'improving': [1795, 5194], 'fitness': [1797, 2119, 5196, 5518], '(7Moreno': [1798, 5197], 'RNA-binding': [1820, 5219], 'recognizes': [1823, 1950, 5222, 5349], 'target': [1833, 2524, 2550, 2707, 2758, 3032, 3323, 3491, 5232], 'mRNAs,': [1834, 2197, 2952, 3148, 3170, 5233], 'inhibiting': [1835, 3192, 5234], '(30Moreno': [1837, 5236], 'Ruiz-Manzano': [1839, 5238], '2007;': [1847, 3284, 5246], '64:': [1848, 5247], '665-675Crossref': [1849, 5248], '(84)': [1852, 5251], '31Moreno': [1855, 3471, 5254], '190:': [1862, 2211, 3478, 5261], '1539-1545Crossref': [1863, 2212, 3479, 5262], '(70)': [1866, 2215, 3482, 5265], '32Moreno': [1869, 2218, 5268], 'Marzi': [1871, 1958, 2220, 5270, 5357], 'Romby': [1873, 1960, 2222, 5272, 5359], 'Nucleic': [1877, 1964, 2226, 3281, 5276, 5363], 'Acids': [1878, 1965, 2227, 3282, 5277, 5364], 'Res.': [1879, 1966, 2228, 3283, 5278, 5365], '37:': [1881, 1968, 2230, 5280, 5367], '7678-7690Crossref': [1882, 1969, 2231, 5281, 5368], '(78)': [1885, 1972, 2234, 3227, 5284, 5371], 'aeruginosa,': [1890, 5289], 'free': [1894, 5293], 'cell': [1898, 2093, 2450, 3887, 5297, 5492], 'regulated': [1900, 2196, 2417, 5299], 'small': [1903, 3254, 5302], 'RNA': [1904, 5303], 'named': [1905, 5304], 'CrcZ,': [1906, 5305], 'sequesters': [1911, 5310], '(33Sonnleitner': [1913, 5312], 'E.': [1914, 1976, 2238, 3209, 3584, 5313, 5375], 'Abdou': [1915, 1977, 2239, 5314, 5376], 'Haas': [1917, 1979, 2241, 5316, 5378], 'D.': [1918, 1980, 2242, 3214, 5317, 5379], '106:': [1925, 1987, 2249, 5324, 5386], '21866-21871Crossref': [1926, 1988, 2250, 5325, 5387], '(191)': [1929, 1991, 2253, 5328, 5390], 'CrcZ': [1932, 5331], 'turn': [1935, 3057, 5334], 'varies': [1936, 5335], 'depending': [1937, 5336], 'composition.Footprinting': [1941, 5340], 'mutagenesis': [1943, 5342], 'techniques': [1944, 5343], 'shown': [1946, 2319, 2421, 5345], 'specifically': [1949, 5348], 'short': [1952, 5351], 'unpaired': [1953, 5352], 'AA(C/U)AA(C/U)AA': [1954, 5353], 'motif': [1955, 2004, 5354, 5403], '(32Moreno': [1956, 5355], '33Sonnleitner': [1975, 2237, 5374], 'Several': [1994, 5393], 'show': [1998, 2039, 2505, 3781, 5397, 5438], 'sequences': [1999, 2020, 2887, 2902, 5398, 5419], 'similar': [2000, 2888, 3189, 5399], 'close': [2005, 5404], 'start': [2009, 5408], 'site.': [2010, 5409], 'analyzes': [2014, 5413], 'whether': [2015, 5414], 'bind': [2018, 5417], 'examines': [2022, 5421], 'effect': [2024, 2276, 2386, 2396, 2508, 2791, 2854, 2992, 3076, 3439, 3636, 3645, 3852, 5423], 'results': [2038, 2124, 2504, 2712, 3776, 5437], 'modulates': [2042, 5441], 'interfering': [2050, 5449], 'some': [2065, 2176, 3208, 3666, 5464], 'encoding': [2068, 5467], 'uptake': [2073, 2410, 3505, 3614, 3650, 5472], 'substrates.': [2078, 5477], 'remarkable': [2082, 5481], 'example': [2083, 5482], 'host': [2092, 5491], 'interfere': [2095, 5494], 'conjugative': [2106, 5505], 'plasmid,': [2107, 5506], 'aim': [2110, 5509], 'being': [2111, 2525, 5510], 'improvement': [2113, 5512], 'efficiency': [2117, 3543, 5516], 'bacterium.DISCUSSIONThe': [2122], 'indicate': [2125, 2328, 2382, 2713], 'levels.': [2140], 'reflected': [2156], '2–3': [2159, 3062], 'lower': [2161], 'key': [2177], 'pathway.': [2182, 3182, 3642], 'Most': [2183], 'notably,': [2184], 'targets': [2186, 2915], '5′-end': [2193], 'observed': [2199], 'Crc-regulated': [2202], '(31Moreno': [2204], 'internal': [2259, 2947, 2972, 3142, 3196, 3617], 'positions': [2260, 2948], 'Fig.': [2268], '7': [2269], 'diagram': [2272], 'showing': [2273, 2851], 'genes.FIGURE': [2283], '7Crc-mediated': [2284], 'genes.A,': [2290], '(in': [2294, 2302], 'gray),': [2295], 'white),': [2303], 'Pu,': [2306, 2378], 'Pm,': [2307, 2379], 'PS2,': [2309, 2704], 'PR1,': [2310], 'PR2': [2312], 'top': [2322], 'figure.': [2325], 'Black': [2326], 'arrowheads': [2327, 2365, 2370], 'direction': [2330], 'transcription.': [2332], 'corresponding': [2335], 'operons': [2341], 'indicated': [2350, 2362, 2432], 'dotted': [2352], 'arrows.': [2353], 'filled': [2364], '(strong': [2366], 'sites)': [2367], 'open': [2369, 2374], '(weak': [2371], 'sites).': [2372], 'triangles': [2375], 'over': [2376], 'indirect': [2384], 'repressing': [2385, 3438], 'derived': [2392], 'direct': [2395, 2523], 'B,': [2405], 'Proteins': [2413], 'boldface,': [2423], 'affected': [2428], 'Roman': [2434], 'text.': [2435], 'XO,': [2436], 'monooxygenase;': [2438], 'TO,': [2439], 'toluate/benzoate': [2440], 'dioxygenase;': [2441], 'DHCDH,': [2442], 'dihydroxycyclohexadiene': [2443], 'carboxylate': [2444], 'dehydrogenase;': [2445, 2448], 'AZDH,': [2446], 'acetaldehyde': [2447], 'CW,': [2449], 'wall.View': [2451], 'Large': [2452], 'Image': [2453], 'Figure': [2454], 'ViewerDownload': [2455], 'Hi-res': [2456], 'image': [2457], 'Download': [2458], '(PPT)It': [2459], 'was': [2460, 2576, 2903, 2997, 3134, 3494], 'earlier': [2461, 3091], 'reported': [2462, 3149], 'leads': [2465, 2665], 'reduced': [2468, 2981], 'no': [2477, 2537], 'mechanistic': [2478], 'explanation': [2479], 'could': [2480], 'advanced': [2482], 'time': [2485], 'indirect,': [2521], 'XylR,': [2526], 'Although': [2534, 3522], 'had': [2536], 'measurable': [2538], 'influence': [2539], 'mRNA,': [2545], 'bound': [2547], 'overlaps': [2552], 'region,': [2557], 'leading': [2558], 'clear': [2561], 'reduction': [2562, 2572, 3040, 3051, 3066], 'Crc-dependent': [2571, 3050], 'paralleled': [2577], '2–3-fold': [2580], 'decrease': [2581], 'explained': [2595, 2725, 3047], 'if': [2596, 2726, 3678], 'assumed': [2599, 2729], 'below': [2605], 'needed': [2607], 'full': [2610, 2744], 'promoter.': [2615, 2749], 'addition,': [2617, 2751], 'action': [2627, 2812], 'activator,': [2632], 'inducer': [2650, 2786], '3MBA,': [2653, 2789], 'XylR-dependent': [2662], 'transcript': [2668, 2695], 'much': [2670], '(14González-Pérez': [2678], 'Crc.': [2709], 'half,': [2721], 'insufficient': [2740], 'attain': [2742], 'should': [2767], 'XylS.': [2772], 'Therefore,': [2773], 'here': [2776, 3150], 'belong': [2802], 'due': [2808], 'combined': [2811], '(which': [2820], 'determines': [2821], 'will': [2832], 'abundant)': [2835], 'PS1.This': [2847], 'limited': [2866], 'proteins.': [2877], 'contained': [2886, 3305, 3321], 'previously': [2891], 'characterized': [2892], 'targets.': [2894], 'recognize': [2900], 'confirmed': [2904], 'band-shift': [2906], 'assays': [2907], 'purified': [2909], '5′-ends': [2920], 'transcripts,': [2926], 'xylU': [2934], 'xylX': [2936], 'respectively.': [2938], 'six': [2941], 'targets,': [2943], 'however,': [2944], 'mapped': [2945], 'xylM,': [2960], 'xylA,': [2961], 'xylB,': [2962], 'xylN,': [2963, 3495], 'xylL,': [2964], 'xylQ': [2966], 'functionality': [2969], 'supported': [2975], 'observation': [2978], 'BADH': [2986, 3068, 3089], 'enzyme': [2987, 2996], 'nine': [2988], 'times,': [2989], 'BZDH': [2995, 3042], 'three': [3004, 3320], 'times.': [3005, 3063], 'These': [3006, 3549], 'xylB': [3012, 3029], 'xylC,': [3014], 'respectively,': [3015], 'same': [3021], 'differ': [3026], 'Crc,': [3034, 3311, 3325], 'xylC': [3036], 'not.': [3038], '(xylC)': [3043], 'levels,': [3054], 'higher': [3065], '(xylB)': [3069], 'probably': [3071, 3671], 'derives': [3072], 'additive': [3075], 'xylB.': [3085], 'Post-transcriptional': [3086], 'suggested': [3093], 'growing': [3096], 'phosphorous,': [3098], 'sulfur,': [3099], 'nitrogen': [3101], 'limitation': [3102], 'containing': [3104], 'excess': [3107], '(23Duetz': [3108], 'responsible': [3130, 3766], 'identified': [3136], 'time.The': [3139], 'time,': [3154], 'presumably': [3171], 'optimizing': [3172], 'each': [3176], 'component': [3177], 'given': [3180], 'follow': [3187], 'strategy,': [3190], 'selectively': [3191], 'mRNA.': [3202], 'case': [3206], 'coli': [3210], 'ribosomal': [3211], '(43Dean': [3213], 'Nomura': [3215, 3238], '1980;': [3222], '77:': [3223], '3590-3594Crossref': [3224], '44Cerretti': [3230], 'D.P.': [3231], 'Mattheakis': [3232], 'L.C.': [3233], 'Kearney': [3234], 'K.R.': [3235], 'Vu': [3236], '1988;': [3243], '204:': [3244], '309-329Crossref': [3245], '(62)': [3248], 'antisense': [3255], 'RNAs': [3256], '(45Møller': [3257], 'Franch': [3259], 'Udesen': [3261], 'Gerdes': [3263], 'Valentin-Hansen': [3265], 'Genes': [3267], 'Dev.': [3268], '16:': [3270], '1696-1706Crossref': [3271], '(235)': [3274], '46Urban': [3277], 'J.H.': [3278], 'Vogel': [3279], '35:': [3285], '1018-1037Crossref': [3286], '(270)': [3289], 'Scholar).It': [3291], 'worth': [3293], 'noting': [3294], 'five': [3296], 'seven': [3299], 'site': [3309], 'among': [3313], '13': [3315], 'weak.': [3330], 'suggests': [3332], 'tighter': [3334], 'i.e.': [3347], 'transforming': [3349], 'toluene/xylenes': [3350], 'benzoate/methylbenzoates.': [3352], 'generated': [3355], 'degraded': [3360], 'through': [3361, 3368], 'pWW0-encoded': [3363], 'chromosomally': [3370], 'ortho': [3373, 3445], '"chromosomal"': [3377], '(15Domínguez-Cuevas': [3389], '47Cowles': [3416], 'C.E.': [3417], 'Nichols': [3418], 'N.N.': [3419, 3572], 'Harwood': [3420, 3573], 'C.S.': [3421, 3574], '6339-6346Crossref': [3426], '(104)': [3429], 'exerts': [3435], 'chromosomal': [3444], 'Scholar).One': [3484], 'showed': [3489], 'encodes': [3497], 'outer': [3499], 'membrane': [3500], '(48Kasai': [3506], 'Y.': [3507], 'Inoue': [3508], '6662-6666Crossref': [3516], '(51)': [3519], 'diffuse': [3526], 'across': [3527], 'membranes,': [3529], 'particularly': [3530, 3551], '(millimolar)': [3535], 'concentrations,': [3536, 3564], 'specificity': [3538], 'transport': [3539], 'increase': [3541], 'rate': [3545], 'substrate': [3547, 3683], 'uptake.': [3548], 'compound': [3556, 3689], 'question': [3558], '(micromolar)': [3563], 'commonly': [3566], 'natural': [3569], 'environments': [3570], '(49Nichols': [3571], '179:': [3578], '5056-5061Crossref': [3579], '50Díaz': [3583], 'Ferrández': [3585], 'Prieto': [3587], 'M.A.': [3588], 'García': [3589], '65:': [3596], '523-569Crossref': [3597], '(278)': [3600], 'Reducing': [3603], 'XylN': [3608], 'porin': [3609], 'would': [3610], 'therefore': [3611, 3714], 'diminish': [3612], 'concentration': [3618], 'act': [3624, 3844], 'regulator,': [3631], 'generating': [3633], 'multiplicative': [3635], 'overall': [3644], 'assures': [3672], 'very': [3674], 'fast': [3675], 'repressive': [3676], 'metabolizing': [3680], 'suddenly': [3684], 'find': [3685], 'fact,': [3694], 'generally': [3698], 'believed': [3699], 'provide': [3701], 'changes': [3706], 'step': [3717], 'gene': [3722], '(51Romby': [3724], 'Springer': [3726], 'Trends': [3728], 'Genet.': [3729], '2003;': [3730], '155-161Abstract': [3732], '(68)': [3740], 'Scholar).The': [3742], 'processes': [3744], 'depth.': [3757], 'Earlier': [3758], 'efforts': [3759], 'elucidate': [3763], 'mechanisms': [3765], 'presented': [3777], 'layer': [3789], 'post-transcriptional': [3796], 'source': [3807], 'Interestingly,': [3815], 'layers': [3818], 'connected': [3822], 'and,': [3835], 'presumably,': [3836], 'entry': [3838], 'regulators.': [3849], 'reduced,': [3855], 'abolished,': [3858], 'emphasizes': [3871], 'complexity': [3873], 'finely': [3883], 'tuned': [3884], 'integration': [3885], 'physiology.': [3888], 'bacterium.': [5521]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2107556244', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 5}, {'year': 2021, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 8}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-14T15:43:46.002171', 'created_date': '2016-06-24'}