Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2107219801', 'doi': 'https://doi.org/10.1006/dbio.2001.0258', 'title': 'Neural Induction in the Absence of Mesoderm: β-Catenin-Dependent Expression of Secreted BMP Antagonists at the Blastula Stage in Xenopus', 'display_name': 'Neural Induction in the Absence of Mesoderm: β-Catenin-Dependent Expression of Secreted BMP Antagonists at the Blastula Stage in Xenopus', 'publication_year': 2001, 'publication_date': '2001-06-01', 'ids': {'openalex': 'https://openalex.org/W2107219801', 'doi': 'https://doi.org/10.1006/dbio.2001.0258', 'mag': '2107219801', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11356027', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3039525'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1006/dbio.2001.0258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136634221', 'display_name': 'Developmental Biology', 'issn_l': '0012-1606', 'issn': ['0012-1606', '1095-564X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://doi.org/10.1006/dbio.2001.0258', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5084946665', 'display_name': 'Oliver Wessely', 'orcid': 'https://orcid.org/0000-0001-6440-7975'}, 'institutions': [{'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Oliver Wessely', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, University of California, Los Angeles, California 90095-1662, USA.'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, University of California, Los Angeles, California 90095-1662, USA.', 'institution_ids': ['https://openalex.org/I161318765']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024359148', 'display_name': 'Eric Agius', 'orcid': 'https://orcid.org/0000-0003-2123-9283'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Eric Agius', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I161318765']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066475986', 'display_name': 'Michael Oelgeschläger', 'orcid': 'https://orcid.org/0000-0002-5787-5540'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael Oelgeschläger', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I161318765']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037667875', 'display_name': 'Edgar M. Pera', 'orcid': 'https://orcid.org/0000-0002-0625-0006'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Edgar M. Pera', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I161318765']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5001643742', 'display_name': 'Edward M. De Robertis', 'orcid': 'https://orcid.org/0000-0002-7843-1869'}, 'institutions': [{'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}, {'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'E.M. De Robertis', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Department of Biological Chemistry, University of California, Los Angeles, California, 90095-1662', 'institution_ids': ['https://openalex.org/I1344073410', 'https://openalex.org/I161318765']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3690, 'currency': 'USD', 'value_usd': 3690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.768, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 125, 'citation_normalized_percentile': {'value': 0.999975, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '234', 'issue': '1', 'first_page': '161', 'last_page': '173'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10268', 'display_name': 'Notch Signaling Pathway in Development and Disease', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10268', 'display_name': 'Notch Signaling Pathway in Development and Disease', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10929', 'display_name': 'Wnt Signaling in Development and Disease', 'score': 0.9931, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11077', 'display_name': 'Sex Determination and Differentiation in Organisms', 'score': 0.9838, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chordin', 'display_name': 'Chordin', 'score': 0.94540554}, {'id': 'https://openalex.org/keywords/blastula', 'display_name': 'Blastula', 'score': 0.89844555}, {'id': 'https://openalex.org/keywords/neural-development', 'display_name': 'Neural development', 'score': 0.65187293}, {'id': 'https://openalex.org/keywords/follistatin', 'display_name': 'Follistatin', 'score': 0.5160279}, {'id': 'https://openalex.org/keywords/neuroectoderm', 'display_name': 'Neuroectoderm', 'score': 0.4704591}, {'id': 'https://openalex.org/keywords/wnt-signaling', 'display_name': 'Wnt Signaling', 'score': 0.460049}], 'concepts': [{'id': 'https://openalex.org/C83484664', 'wikidata': 'https://www.wikidata.org/wiki/Q24727001', 'display_name': 'Chordin', 'level': 5, 'score': 0.94540554}, {'id': 'https://openalex.org/C2778761762', 'wikidata': 'https://www.wikidata.org/wiki/Q18252680', 'display_name': 'Noggin', 'level': 4, 'score': 0.93052745}, {'id': 'https://openalex.org/C6047887', 'wikidata': 'https://www.wikidata.org/wiki/Q420811', 'display_name': 'Blastula', 'level': 5, 'score': 0.89844555}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7922121}, {'id': 'https://openalex.org/C129536746', 'wikidata': 'https://www.wikidata.org/wiki/Q1141026', 'display_name': 'Gastrulation', 'level': 4, 'score': 0.736343}, {'id': 'https://openalex.org/C2780915607', 'wikidata': 'https://www.wikidata.org/wiki/Q323438', 'display_name': 'Mesoderm', 'level': 4, 'score': 0.7326247}, {'id': 'https://openalex.org/C461258', 'wikidata': 'https://www.wikidata.org/wiki/Q1345738', 'display_name': 'Neural development', 'level': 3, 'score': 0.65187293}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.6165134}, {'id': 'https://openalex.org/C2779535977', 'wikidata': 'https://www.wikidata.org/wiki/Q1342298', 'display_name': 'Xenopus', 'level': 3, 'score': 0.5990633}, {'id': 'https://openalex.org/C197849852', 'wikidata': 'https://www.wikidata.org/wiki/Q2314823', 'display_name': 'Neural plate', 'level': 4, 'score': 0.59158593}, {'id': 'https://openalex.org/C2778831791', 'wikidata': 'https://www.wikidata.org/wiki/Q408122', 'display_name': 'Follistatin', 'level': 2, 'score': 0.5160279}, {'id': 'https://openalex.org/C135073763', 'wikidata': 'https://www.wikidata.org/wiki/Q1271432', 'display_name': 'Neuroectoderm', 'level': 5, 'score': 0.4704591}, {'id': 'https://openalex.org/C126749454', 'wikidata': 'https://www.wikidata.org/wiki/Q1348455', 'display_name': 'Neural crest', 'level': 3, 'score': 0.40065685}, {'id': 'https://openalex.org/C31507581', 'wikidata': 'https://www.wikidata.org/wiki/Q425383', 'display_name': 'Bone morphogenetic protein', 'level': 3, 'score': 0.38621894}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.3239745}, {'id': 'https://openalex.org/C196843134', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryo', 'level': 2, 'score': 0.2907452}, {'id': 'https://openalex.org/C87073359', 'wikidata': 'https://www.wikidata.org/wiki/Q33196', 'display_name': 'Embryogenesis', 'level': 3, 'score': 0.24534309}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.17735669}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.15982425}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D004627', 'descriptor_name': 'Embryonic Induction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008648', 'descriptor_name': 'Mesoderm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009432', 'descriptor_name': 'Neural Crest', 'qualifier_ui': 'Q000196', 'qualifier_name': 'embryology', 'is_major_topic': True}, {'descriptor_ui': 'D020897', 'descriptor_name': 'Organizers, Embryonic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015534', 'descriptor_name': 'Trans-Activators', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D029867', 'descriptor_name': 'Xenopus Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001755', 'descriptor_name': 'Blastocyst', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019485', 'descriptor_name': 'Bone Morphogenetic Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002352', 'descriptor_name': 'Carrier Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002490', 'descriptor_name': 'Central Nervous System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003598', 'descriptor_name': 'Cytoskeletal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004625', 'descriptor_name': 'Embryo, Nonmammalian', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D038681', 'descriptor_name': 'Follistatin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D036341', 'descriptor_name': 'Intercellular Signaling Peptides and Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009432', 'descriptor_name': 'Neural Crest', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016212', 'descriptor_name': 'Transforming Growth Factor beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016212', 'descriptor_name': 'Transforming Growth Factor beta', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014981', 'descriptor_name': 'Xenopus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051176', 'descriptor_name': 'beta Catenin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1006/dbio.2001.0258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136634221', 'display_name': 'Developmental Biology', 'issn_l': '0012-1606', 'issn': ['0012-1606', '1095-564X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3039525', 'pdf_url': 'https://europepmc.org/articles/pmc3039525?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3039525', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'acceptedVersion', 'is_accepted': True, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11356027', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1006/dbio.2001.0258', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S136634221', 'display_name': 'Developmental Biology', 'issn_l': '0012-1606', 'issn': ['0012-1606', '1095-564X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'publisher-specific-oa', 'license_id': 'https://openalex.org/licenses/publisher-specific-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 73, 'referenced_works': ['https://openalex.org/W1486617321', 'https://openalex.org/W1489916230', 'https://openalex.org/W1507923114', 'https://openalex.org/W1523269786', 'https://openalex.org/W1533376056', 'https://openalex.org/W1554593075', 'https://openalex.org/W1566519945', 'https://openalex.org/W1594765203', 'https://openalex.org/W1657005131', 'https://openalex.org/W1680418198', 'https://openalex.org/W1883820456', 'https://openalex.org/W1927171786', 'https://openalex.org/W1941036671', 'https://openalex.org/W1945116336', 'https://openalex.org/W1976754131', 'https://openalex.org/W1984288177', 'https://openalex.org/W1986864689', 'https://openalex.org/W1990938412', 'https://openalex.org/W2008777486', 'https://openalex.org/W2010854221', 'https://openalex.org/W2013154305', 'https://openalex.org/W2014371162', 'https://openalex.org/W2017846412', 'https://openalex.org/W2025019677', 'https://openalex.org/W2026118162', 'https://openalex.org/W2031984950', 'https://openalex.org/W2037143749', 'https://openalex.org/W2038073573', 'https://openalex.org/W2042859849', 'https://openalex.org/W2046597024', 'https://openalex.org/W2046813157', 'https://openalex.org/W2051788298', 'https://openalex.org/W2067545062', 'https://openalex.org/W2068807517', 'https://openalex.org/W2073239747', 'https://openalex.org/W2074773822', 'https://openalex.org/W2078058386', 'https://openalex.org/W2081939122', 'https://openalex.org/W2082955515', 'https://openalex.org/W2085672851', 'https://openalex.org/W2090636859', 'https://openalex.org/W2091637225', 'https://openalex.org/W2092125592', 'https://openalex.org/W2096614956', 'https://openalex.org/W2098737761', 'https://openalex.org/W2100223050', 'https://openalex.org/W2105884976', 'https://openalex.org/W2109052299', 'https://openalex.org/W2115686163', 'https://openalex.org/W2120643964', 'https://openalex.org/W2121653039', 'https://openalex.org/W2125068279', 'https://openalex.org/W2128817019', 'https://openalex.org/W2131304500', 'https://openalex.org/W2131716017', 'https://openalex.org/W2132584224', 'https://openalex.org/W2140215295', 'https://openalex.org/W2145559277', 'https://openalex.org/W2150068899', 'https://openalex.org/W2155920443', 'https://openalex.org/W2156212940', 'https://openalex.org/W2158071345', 'https://openalex.org/W2158129482', 'https://openalex.org/W2164413753', 'https://openalex.org/W2184976335', 'https://openalex.org/W2215928152', 'https://openalex.org/W2343682660', 'https://openalex.org/W2423159520', 'https://openalex.org/W2462789914', 'https://openalex.org/W2463018690', 'https://openalex.org/W4243347737', 'https://openalex.org/W629998573', 'https://openalex.org/W638406814'], 'related_works': ['https://openalex.org/W2148514691', 'https://openalex.org/W2107219801', 'https://openalex.org/W2100223050', 'https://openalex.org/W2097923096', 'https://openalex.org/W2085526312', 'https://openalex.org/W2074091076', 'https://openalex.org/W2071835533', 'https://openalex.org/W2012869310', 'https://openalex.org/W1992859895', 'https://openalex.org/W1973848071'], 'abstract_inverted_index': {'A': [0], 'growing': [1], 'body': [2], 'of': [3, 16, 63, 72, 91, 106, 128, 149, 164, 166, 181], 'work': [4, 133], 'indicates': [5], 'that': [6, 40, 48], 'neural': [7, 24, 50, 66, 111, 142], 'induction': [8, 25, 32, 67, 143], 'may': [9], 'be': [10], 'initiated': [11], 'prior': [12], 'to': [13, 104], 'the': [14, 17, 61, 70, 83, 92, 121, 126, 146, 161, 178, 182], 'establishment': [15], 'gastrula': [18], 'mesodermal': [19], 'organizer.': [20], 'Here,': [21], 'we': [22], 'examine': [23], 'in': [26, 29, 113, 141, 173, 177], 'Xenopus': [27, 183], 'embryos': [28], 'which': [30], 'mesoderm': [31], 'has': [33, 134], 'been': [34], 'blocked': [35], 'by': [36, 95, 99, 145], 'Cerberus-short,': [37], 'a': [38, 136, 174], 'reagent': [39], 'specifically': [41], 'inhibits': [42], 'Nodal-related': [43], '(Xnr)': [44], 'signals.': [45], 'We': [46], 'find': [47], 'extensive': [49], 'structures': [51], 'with': [52, 69, 101], 'cyclopic': [53], 'eyes': [54], 'and': [55, 74, 81, 86], 'brain': [56], 'tissue': [57], 'are': [58, 118], 'formed': [59], 'despite': [60], 'absence': [62], 'mesoderm.': [64], 'This': [65], 'correlates': [68], 'expression': [71, 165], 'chordin': [73], 'other': [75], 'BMP': [76, 129, 168], 'inhibitors—such': [77], 'as': [78, 108, 110, 171], 'noggin,': [79], 'follistatin,': [80], 'Xnr3—at': [82], 'blastula': [84], 'stage,': [85], 'requires': [87], 'β-Catenin': [88, 93, 139], 'signaling.': [89], 'Activation': [90], 'pathway': [94], 'mRNA': [96], 'microinjections': [97], 'or': [98], 'treatment': [100], 'LiCl': [102], 'leads': [103], 'differentiation': [105], 'neurons,': [107], 'well': [109], 'crest,': [112], 'ectodermal': [114], 'explants.': [115], 'Xnr': [116], 'signals': [117], 'required': [119], 'for': [120, 125, 138, 159], 'maintenance,': [122], 'but': [123], 'not': [124], 'initiation,': [127], 'antagonist': [130], 'expression.': [131, 151], 'Recent': [132], 'demonstrated': [135], 'role': [137], 'signaling': [140], 'mediated': [144], 'transcriptional': [147], 'down-regulation': [148], 'BMP-4': [150], 'The': [152], 'present': [153], 'results': [154], 'suggest': [155], 'an': [156], 'additional': [157], 'function': [158], 'β-Catenin,': [160], 'early': [162], 'activation': [163], 'secreted': [167], 'antagonists,': [169], 'such': [170], 'Chordin,': [172], 'preorganizer': [175], 'region': [176], 'dorsal': [179], 'side': [180], 'blastula.': [184]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2107219801', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 3}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 6}], 'updated_date': '2024-08-15T09:27:18.648619', 'created_date': '2016-06-24'}