Publication Information

{'id': 'https://openalex.org/W2106402868', 'doi': 'https://doi.org/10.1111/j.1440-1789.2011.01204.x', 'title': 'Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study', 'display_name': 'Amplification of the PDGFRA, KIT and KDR genes in glioblastoma: a population-based study', 'publication_year': 2011, 'publication_date': '2011-03-07', 'ids': {'openalex': 'https://openalex.org/W2106402868', 'doi': 'https://doi.org/10.1111/j.1440-1789.2011.01204.x', 'mag': '2106402868', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21382095'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1440-1789.2011.01204.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1789.2011.01204.x', 'source': {'id': 'https://openalex.org/S43667197', 'display_name': 'Neuropathology', 'issn_l': '0919-6544', 'issn': ['0919-6544', '1440-1789'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1789.2011.01204.x', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5051624965', 'display_name': 'Sumihito Nobusawa', 'orcid': 'https://orcid.org/0000-0001-9434-8400'}, 'institutions': [{'id': 'https://openalex.org/I165735259', 'display_name': 'Gunma University', 'ror': 'https://ror.org/046fm7598', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I165735259']}, {'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR', 'JP'], 'is_corresponding': False, 'raw_author_name': 'Sumihito Nobusawa', 'raw_affiliation_strings': ['Department of Pathology, Gunma University, Gunma, Japan', 'International Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Gunma University, Gunma, Japan', 'institution_ids': ['https://openalex.org/I165735259']}, {'raw_affiliation_string': 'International Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054329930', 'display_name': 'Robert Stawski', 'orcid': 'https://orcid.org/0000-0003-4164-4817'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Robert Stawski', 'raw_affiliation_strings': ['International Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'International Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100335103', 'display_name': 'Young Ho Kim', 'orcid': 'https://orcid.org/0000-0003-0703-1136'}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Young-Ho Kim', 'raw_affiliation_strings': ['International Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'International Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103417109', 'display_name': 'Yoichi Nakazato', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I165735259', 'display_name': 'Gunma University', 'ror': 'https://ror.org/046fm7598', 'country_code': 'JP', 'type': 'education', 'lineage': ['https://openalex.org/I165735259']}], 'countries': ['JP'], 'is_corresponding': False, 'raw_author_name': 'Yoichi Nakazato', 'raw_affiliation_strings': ['Department of Pathology, Gunma University, Gunma, Japan'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, Gunma University, Gunma, Japan', 'institution_ids': ['https://openalex.org/I165735259']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103530823', 'display_name': 'Hiroko Ohgaki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I42237331', 'display_name': 'Centre International de Recherche sur le Cancer', 'ror': 'https://ror.org/00v452281', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I42237331']}], 'countries': ['FR'], 'is_corresponding': True, 'raw_author_name': 'Hiroko Ohgaki', 'raw_affiliation_strings': ['International Agency for Research on Cancer, Lyon, France'], 'affiliations': [{'raw_affiliation_string': 'International Agency for Research on Cancer, Lyon, France', 'institution_ids': ['https://openalex.org/I42237331']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 2, 'corresponding_author_ids': ['https://openalex.org/A5103530823'], 'corresponding_institution_ids': ['https://openalex.org/I42237331'], 'apc_list': {'value': 3240, 'currency': 'USD', 'value_usd': 3240, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.49, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 45, 'citation_normalized_percentile': {'value': 0.999823, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '31', 'issue': '6', 'first_page': '583', 'last_page': '588'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10253', 'display_name': 'Sarcoma Diagnosis and Treatment', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11173', 'display_name': 'Neurofibromatosis and Schwannoma Cases', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2728', 'display_name': 'Neurology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pdgfra', 'display_name': 'PDGFRA', 'score': 0.9790729}], 'concepts': [{'id': 'https://openalex.org/C37307934', 'wikidata': 'https://www.wikidata.org/wiki/Q18030422', 'display_name': 'PDGFRA', 'level': 4, 'score': 0.9790729}, {'id': 'https://openalex.org/C7602840', 'wikidata': 'https://www.wikidata.org/wiki/Q746284', 'display_name': 'Gene duplication', 'level': 3, 'score': 0.6333051}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.53116024}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.46411544}, {'id': 'https://openalex.org/C42362537', 'wikidata': 'https://www.wikidata.org/wiki/Q87099740', 'display_name': 'Tyrosine kinase', 'level': 3, 'score': 0.46015576}, {'id': 'https://openalex.org/C2908647359', 'wikidata': 'https://www.wikidata.org/wiki/Q2625603', 'display_name': 'Population', 'level': 2, 'score': 0.45852485}, {'id': 'https://openalex.org/C101544691', 'wikidata': 'https://www.wikidata.org/wiki/Q420511', 'display_name': 'Receptor tyrosine kinase', 'level': 3, 'score': 0.45699877}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.40576902}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.32278755}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.25195926}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.16664362}, {'id': 'https://openalex.org/C2775922572', 'wikidata': 'https://www.wikidata.org/wiki/Q83567', 'display_name': 'GiST', 'level': 3, 'score': 0.07541153}, {'id': 'https://openalex.org/C99454951', 'wikidata': 'https://www.wikidata.org/wiki/Q932068', 'display_name': 'Environmental health', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C16930146', 'wikidata': 'https://www.wikidata.org/wiki/Q4381253', 'display_name': 'Stromal cell', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D005909', 'descriptor_name': 'Glioblastoma', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D019009', 'descriptor_name': 'Proto-Oncogene Proteins c-kit', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D020796', 'descriptor_name': 'Receptor, Platelet-Derived Growth Factor alpha', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D040301', 'descriptor_name': 'Vascular Endothelial Growth Factor Receptor-2', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D001932', 'descriptor_name': 'Brain Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005784', 'descriptor_name': 'Gene Amplification', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005909', 'descriptor_name': 'Glioblastoma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016133', 'descriptor_name': 'Polymerase Chain Reaction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019009', 'descriptor_name': 'Proto-Oncogene Proteins c-kit', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020796', 'descriptor_name': 'Receptor, Platelet-Derived Growth Factor alpha', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D040301', 'descriptor_name': 'Vascular Endothelial Growth Factor Receptor-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1440-1789.2011.01204.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1789.2011.01204.x', 'source': {'id': 'https://openalex.org/S43667197', 'display_name': 'Neuropathology', 'issn_l': '0919-6544', 'issn': ['0919-6544', '1440-1789'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21382095', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1111/j.1440-1789.2011.01204.x', 'pdf_url': 'https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1440-1789.2011.01204.x', 'source': {'id': 'https://openalex.org/S43667197', 'display_name': 'Neuropathology', 'issn_l': '0919-6544', 'issn': ['0919-6544', '1440-1789'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.44, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 34, 'referenced_works': ['https://openalex.org/W1534734027', 'https://openalex.org/W1843891279', 'https://openalex.org/W1953848330', 'https://openalex.org/W2017068782', 'https://openalex.org/W2018101957', 'https://openalex.org/W2025183726', 'https://openalex.org/W2029218543', 'https://openalex.org/W2045274471', 'https://openalex.org/W2053605766', 'https://openalex.org/W2063814386', 'https://openalex.org/W2067764106', 'https://openalex.org/W2070580563', 'https://openalex.org/W2076699304', 'https://openalex.org/W2081454918', 'https://openalex.org/W2090350928', 'https://openalex.org/W2098341282', 'https://openalex.org/W2105348749', 'https://openalex.org/W2115862526', 'https://openalex.org/W2117941094', 'https://openalex.org/W2123151929', 'https://openalex.org/W2124512686', 'https://openalex.org/W2137586969', 'https://openalex.org/W2142776762', 'https://openalex.org/W2146953551', 'https://openalex.org/W2149434165', 'https://openalex.org/W2150268629', 'https://openalex.org/W2150638747', 'https://openalex.org/W2154898479', 'https://openalex.org/W2161289668', 'https://openalex.org/W2167185669', 'https://openalex.org/W2168752603', 'https://openalex.org/W2170429308', 'https://openalex.org/W234178202', 'https://openalex.org/W4244344354'], 'related_works': ['https://openalex.org/W4256504406', 'https://openalex.org/W2903363945', 'https://openalex.org/W2902072959', 'https://openalex.org/W2885427257', 'https://openalex.org/W2149500996', 'https://openalex.org/W2140626630', 'https://openalex.org/W2135874746', 'https://openalex.org/W2125287923', 'https://openalex.org/W2102769930', 'https://openalex.org/W2053150697'], 'abstract_inverted_index': {'The': [0], 'aim': [1], 'of': [2, 10, 12, 41, 53, 71, 112, 165, 167, 186, 197, 201, 204], 'this': [3], 'study': [4, 47], 'was': [5, 74, 130, 146, 160], 'to': [6, 31], 'establish': [7], 'the': [8, 54, 113, 163, 195], 'frequency': [9, 164], 'amplification': [11, 52, 84, 94, 111, 124, 134, 137, 150, 166, 185], 'tyrosine': [13], 'kinase': [14], 'receptor': [15], 'genes': [16, 59, 169], 'PDGFRA,': [17, 55, 114, 187], 'KIT': [18, 56, 83, 115, 133, 149, 188], 'and': [19, 30, 57, 65, 116, 135, 151, 172, 179, 189], 'KDR': [20, 58, 117, 190], '(VEGFR2)': [21], 'at': [22, 26], '4q12': [23], 'in': [24, 60, 162, 170, 176, 194], 'glioblastomas': [25, 43, 108, 121, 174, 177], 'a': [27, 45, 142, 198], 'population': [28], 'level,': [29], 'assess': [32], 'whether': [33], 'such': [34], 'alterations': [35, 73], 'have': [36], 'any': [37], 'clinical': [38], 'impact.': [39], 'Screening': [40], '390': [42], 'from': [44], 'population-based': [46], 'by': [48], 'differential': [49], 'PCR': [50], 'revealed': [51], '33': [61], '(8.5%),': [62], '17': [63], '(4.4%)': [64], '13': [66], '(3.3%)': [67], 'glioblastomas,': [68], 'respectively.': [69], 'None': [70], 'these': [72, 168], 'prognostic': [75], 'for': [76], 'overall': [77], 'survival.': [78], 'Patients': [79], 'with': [80, 90, 178], 'glioblastoma': [81, 91], 'showing': [82, 92], 'were': [85], 'significantly': [86], 'younger': [87], 'than': [88], 'those': [89], 'no': [93], '(51.7': [95], '±': [96, 101], '21.7': [97], 'years': [98], 'vs.': [99], '59.3': [100], '13.1': [102], 'years;': [103], 'P': [104], '=': [105, 139, 155], '0.0231).': [106], 'Twelve': [107], 'showed': [109, 122], 'concurrent': [110], 'genes,': [118], 'whereas': [119, 141], '18': [120], 'PDGFRA': [123], 'only.': [125], 'A': [126], 'significant': [127, 158], 'inverse': [128], 'association': [129, 145], 'observed': [131, 161], 'between': [132, 148], 'EGFR': [136], '(P': [138, 154], '0.0260),': [140], 'borderline': [143], 'positive': [144], 'found': [147], 'TP53': [152], 'mutation': [153], '0.0579).': [156], 'No': [157], 'difference': [159], 'primary': [171], 'secondary': [173], 'or': [175], 'without': [180], 'IDH1': [181], 'mutations,': [182], 'suggesting': [183], 'that': [184], 'may': [191], 'be': [192], 'implicated': [193], 'pathogenesis': [196], 'small': [199], 'fraction': [200], 'both': [202], 'subtypes': [203], 'glioblastoma.': [205]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2106402868', 'counts_by_year': [{'year': 2024, 'cited_by_count': 6}, {'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-30T03:57:23.500306', 'created_date': '2016-06-24'}