Publication Information

{'id': 'https://openalex.org/W2104947461', 'doi': 'https://doi.org/10.1101/gad.12.1.67', 'title': 'A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs', 'display_name': 'A prokaryotic-like mode of cytoplasmic eukaryotic ribosome binding to the initiation codon during internal translation initation of hepatitis C and classical swine fever virus RNAs', 'publication_year': 1998, 'publication_date': '1998-01-01', 'ids': {'openalex': 'https://openalex.org/W2104947461', 'doi': 'https://doi.org/10.1101/gad.12.1.67', 'mag': '2104947461', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9420332', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/316404'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.12.1.67', 'pdf_url': 'http://genesdev.cshlp.org/content/12/1/67.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'http://genesdev.cshlp.org/content/12/1/67.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5067570812', 'display_name': 'Tatyana V. Pestova', 'orcid': 'https://orcid.org/0000-0003-3543-256X'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I19880235', 'display_name': 'Lomonosov Moscow State University', 'ror': 'https://ror.org/010pmpe69', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I19880235']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB', 'RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Tatyana V. Pestova', 'raw_affiliation_strings': ['2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': '2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', 'institution_ids': ['https://openalex.org/I19880235']}, {'raw_affiliation_string': '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103192579', 'display_name': 'Ivan N. Shatsky', 'orcid': 'https://orcid.org/0000-0002-4428-9905'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I19880235', 'display_name': 'Lomonosov Moscow State University', 'ror': 'https://ror.org/010pmpe69', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I19880235']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB', 'RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Ivan N. Shatsky', 'raw_affiliation_strings': ['2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': '2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', 'institution_ids': ['https://openalex.org/I19880235']}, {'raw_affiliation_string': '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5057601477', 'display_name': 'Simon P. Fletcher', 'orcid': 'https://orcid.org/0000-0003-1987-6179'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I19880235', 'display_name': 'Lomonosov Moscow State University', 'ror': 'https://ror.org/010pmpe69', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I19880235']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB', 'RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Simon P. Fletcher', 'raw_affiliation_strings': ['2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': '2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', 'institution_ids': ['https://openalex.org/I19880235']}, {'raw_affiliation_string': '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5008218354', 'display_name': 'Richard J. Jackson', 'orcid': 'https://orcid.org/0000-0002-8840-9198'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I19880235', 'display_name': 'Lomonosov Moscow State University', 'ror': 'https://ror.org/010pmpe69', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I19880235']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB', 'RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Richard J. Jackson', 'raw_affiliation_strings': ['2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': '2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', 'institution_ids': ['https://openalex.org/I19880235']}, {'raw_affiliation_string': '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'institution_ids': ['https://openalex.org/I241749']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5009915941', 'display_name': 'Christopher U.T. Hellen', 'orcid': 'https://orcid.org/0000-0002-3982-2090'}, 'institutions': [{'id': 'https://openalex.org/I1327163397', 'display_name': 'State University of New York', 'ror': 'https://ror.org/01q1z8k08', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I1327163397']}, {'id': 'https://openalex.org/I19880235', 'display_name': 'Lomonosov Moscow State University', 'ror': 'https://ror.org/010pmpe69', 'country_code': 'RU', 'type': 'education', 'lineage': ['https://openalex.org/I19880235']}, {'id': 'https://openalex.org/I241749', 'display_name': 'University of Cambridge', 'ror': 'https://ror.org/013meh722', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I241749']}], 'countries': ['GB', 'RU', 'US'], 'is_corresponding': False, 'raw_author_name': 'Christopher U.T. Hellen', 'raw_affiliation_strings': ['2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203'], 'affiliations': [{'raw_affiliation_string': 'Department of Microbiology and Immunology, Morse Institute for Molecular Genetics, State University of New York Health Science\n                           Center at Brooklyn, Brooklyn, New York 11203', 'institution_ids': ['https://openalex.org/I1327163397']}, {'raw_affiliation_string': '2A.N. Belozersky Institute of Physico-Chemical Biology, Moscow State University, 119899 Moscow, Russia', 'institution_ids': ['https://openalex.org/I19880235']}, {'raw_affiliation_string': '3Department of Biochemistry, University of Cambridge, Cambridge, CB2 1QW, UK', 'institution_ids': ['https://openalex.org/I241749']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 25.411, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 706, 'citation_normalized_percentile': {'value': 0.999899, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '12', 'issue': '1', 'first_page': '67', 'last_page': '83'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11560', 'display_name': 'Animal Disease Management and Epidemiology', 'score': 0.9966, 'subfield': {'id': 'https://openalex.org/subfields/1102', 'display_name': 'Agronomy and Crop Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'RNA and protein synthesis mechanisms', 'score': 0.9934, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/eukaryotic-initiation-factor', 'display_name': 'Eukaryotic initiation factor', 'score': 0.7188645}, {'id': 'https://openalex.org/keywords/initiation-factor', 'display_name': 'Initiation factor', 'score': 0.70707905}, {'id': 'https://openalex.org/keywords/eukaryotic-translation', 'display_name': 'Eukaryotic translation', 'score': 0.66714597}, {'id': 'https://openalex.org/keywords/eukaryotic-ribosome', 'display_name': 'Eukaryotic Ribosome', 'score': 0.43870348}, {'id': 'https://openalex.org/keywords/5.8s-ribosomal-rna', 'display_name': '5.8S ribosomal RNA', 'score': 0.4261889}, {'id': 'https://openalex.org/keywords/eif4g', 'display_name': 'EIF4G', 'score': 0.42042205}, {'id': 'https://openalex.org/keywords/eif4e', 'display_name': 'EIF4E', 'score': 0.41524267}, {'id': 'https://openalex.org/keywords/transcription-preinitiation-complex', 'display_name': 'Transcription preinitiation complex', 'score': 0.4151827}], 'concepts': [{'id': 'https://openalex.org/C77430603', 'wikidata': 'https://www.wikidata.org/wiki/Q166992', 'display_name': 'Internal ribosome entry site', 'level': 5, 'score': 0.78438044}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.7788749}, {'id': 'https://openalex.org/C97154109', 'wikidata': 'https://www.wikidata.org/wiki/Q906570', 'display_name': 'Eukaryotic initiation factor', 'level': 5, 'score': 0.7188645}, {'id': 'https://openalex.org/C62493599', 'wikidata': 'https://www.wikidata.org/wiki/Q424137', 'display_name': 'Initiation factor', 'level': 5, 'score': 0.70707905}, {'id': 'https://openalex.org/C4718897', 'wikidata': 'https://www.wikidata.org/wiki/Q5408698', 'display_name': 'Eukaryotic translation', 'level': 5, 'score': 0.66714597}, {'id': 'https://openalex.org/C301363', 'wikidata': 'https://www.wikidata.org/wiki/Q4637383', 'display_name': 'Eukaryotic Small Ribosomal Subunit', 'level': 5, 'score': 0.6051177}, {'id': 'https://openalex.org/C176990463', 'wikidata': 'https://www.wikidata.org/wiki/Q1854186', 'display_name': 'Start codon', 'level': 4, 'score': 0.5203397}, {'id': 'https://openalex.org/C67905577', 'wikidata': 'https://www.wikidata.org/wiki/Q215980', 'display_name': 'Ribosomal RNA', 'level': 3, 'score': 0.47401103}, {'id': 'https://openalex.org/C129194359', 'wikidata': 'https://www.wikidata.org/wiki/Q2636953', 'display_name': 'Eukaryotic Ribosome', 'level': 5, 'score': 0.43870348}, {'id': 'https://openalex.org/C98098607', 'wikidata': 'https://www.wikidata.org/wiki/Q4639691', 'display_name': '5.8S ribosomal RNA', 'level': 5, 'score': 0.4261889}, {'id': 'https://openalex.org/C2776054693', 'wikidata': 'https://www.wikidata.org/wiki/Q5323186', 'display_name': 'EIF4G', 'level': 5, 'score': 0.42042205}, {'id': 'https://openalex.org/C161295673', 'wikidata': 'https://www.wikidata.org/wiki/Q5408696', 'display_name': 'EIF4E', 'level': 5, 'score': 0.41524267}, {'id': 'https://openalex.org/C188740287', 'wikidata': 'https://www.wikidata.org/wiki/Q423333', 'display_name': 'Transcription preinitiation complex', 'level': 5, 'score': 0.4151827}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.39061022}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.3683722}, {'id': 'https://openalex.org/C149364088', 'wikidata': 'https://www.wikidata.org/wiki/Q185917', 'display_name': 'Translation (biology)', 'level': 4, 'score': 0.3672107}, {'id': 'https://openalex.org/C88478588', 'wikidata': 'https://www.wikidata.org/wiki/Q42244', 'display_name': 'Ribosome', 'level': 4, 'score': 0.3029521}, {'id': 'https://openalex.org/C67705224', 'wikidata': 'https://www.wikidata.org/wiki/Q11053', 'display_name': 'RNA', 'level': 3, 'score': 0.27528268}, {'id': 'https://openalex.org/C105580179', 'wikidata': 'https://www.wikidata.org/wiki/Q188928', 'display_name': 'Messenger RNA', 'level': 3, 'score': 0.19021961}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.08025205}, {'id': 'https://openalex.org/C150194340', 'wikidata': 'https://www.wikidata.org/wiki/Q26972', 'display_name': 'Gene expression', 'level': 3, 'score': 0.061249852}, {'id': 'https://openalex.org/C101762097', 'wikidata': 'https://www.wikidata.org/wiki/Q224093', 'display_name': 'Promoter', 'level': 4, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006692', 'descriptor_name': 'Classical Swine Fever Virus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D018387', 'descriptor_name': 'Codon, Initiator', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D039642', 'descriptor_name': 'Eukaryotic Initiation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D016174', 'descriptor_name': 'Hepacivirus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D014176', 'descriptor_name': 'Protein Biosynthesis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D012270', 'descriptor_name': 'Ribosomes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001483', 'descriptor_name': 'Base Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006692', 'descriptor_name': 'Classical Swine Fever Virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003593', 'descriptor_name': 'Cytoplasm', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017931', 'descriptor_name': 'DNA Primers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005057', 'descriptor_name': 'Eukaryotic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015852', 'descriptor_name': 'Eukaryotic Initiation Factor-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015852', 'descriptor_name': 'Eukaryotic Initiation Factor-2', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015852', 'descriptor_name': 'Eukaryotic Initiation Factor-2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D039621', 'descriptor_name': 'Eukaryotic Initiation Factor-3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039601', 'descriptor_name': 'Eukaryotic Initiation Factor-4A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039562', 'descriptor_name': 'Eukaryotic Initiation Factor-4F', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016174', 'descriptor_name': 'Hepacivirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008969', 'descriptor_name': 'Molecular Sequence Data', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009690', 'descriptor_name': 'Nucleic Acid Conformation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010442', 'descriptor_name': 'Peptide Chain Initiation, Translational', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010448', 'descriptor_name': 'Peptide Initiation Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010448', 'descriptor_name': 'Peptide Initiation Factors', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010448', 'descriptor_name': 'Peptide Initiation Factors', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011387', 'descriptor_name': 'Prokaryotic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012358', 'descriptor_name': 'RNA, Transfer, Met', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012358', 'descriptor_name': 'RNA, Transfer, Met', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012367', 'descriptor_name': 'RNA, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011817', 'descriptor_name': 'Rabbits', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000091243', 'descriptor_name': 'Ribosomal Protein S9', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012269', 'descriptor_name': 'Ribosomal Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012270', 'descriptor_name': 'Ribosomes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013329', 'descriptor_name': 'Structure-Activity Relationship', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.12.1.67', 'pdf_url': 'http://genesdev.cshlp.org/content/12/1/67.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc316404', 'pdf_url': 'https://europepmc.org/articles/pmc316404?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC316404', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9420332', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1101/gad.12.1.67', 'pdf_url': 'http://genesdev.cshlp.org/content/12/1/67.full.pdf', 'source': {'id': 'https://openalex.org/S168778273', 'display_name': 'Genes & Development', 'issn_l': '0890-9369', 'issn': ['0890-9369', '1549-5477'], 'is_oa': True, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315909', 'host_organization_name': 'Cold Spring Harbor Laboratory Press', 'host_organization_lineage': ['https://openalex.org/P4310315909'], 'host_organization_lineage_names': ['Cold Spring Harbor Laboratory Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.77, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 50, 'referenced_works': ['https://openalex.org/W118864685', 'https://openalex.org/W1481065513', 'https://openalex.org/W1481908209', 'https://openalex.org/W1493978240', 'https://openalex.org/W1625101491', 'https://openalex.org/W1763659965', 'https://openalex.org/W1776345984', 'https://openalex.org/W1823239410', 'https://openalex.org/W1902706292', 'https://openalex.org/W1914838920', 'https://openalex.org/W1920555941', 'https://openalex.org/W1966896083', 'https://openalex.org/W1968698767', 'https://openalex.org/W1969120595', 'https://openalex.org/W1969215695', 'https://openalex.org/W1969723726', 'https://openalex.org/W1979877802', 'https://openalex.org/W1990884146', 'https://openalex.org/W1992378816', 'https://openalex.org/W2003560259', 'https://openalex.org/W2003568337', 'https://openalex.org/W2004290704', 'https://openalex.org/W2006923455', 'https://openalex.org/W2013732276', 'https://openalex.org/W2024814135', 'https://openalex.org/W2027150388', 'https://openalex.org/W2037532701', 'https://openalex.org/W2050502218', 'https://openalex.org/W2066390723', 'https://openalex.org/W2073354904', 'https://openalex.org/W2074816425', 'https://openalex.org/W2077140822', 'https://openalex.org/W2079044607', 'https://openalex.org/W2085460053', 'https://openalex.org/W2087021327', 'https://openalex.org/W2098206590', 'https://openalex.org/W2099390806', 'https://openalex.org/W2104573851', 'https://openalex.org/W2122644139', 'https://openalex.org/W2122767802', 'https://openalex.org/W2129430102', 'https://openalex.org/W2148510296', 'https://openalex.org/W2159607998', 'https://openalex.org/W2166661434', 'https://openalex.org/W2168694015', 'https://openalex.org/W2290134688', 'https://openalex.org/W2432859081', 'https://openalex.org/W48741435', 'https://openalex.org/W58563855', 'https://openalex.org/W60878782'], 'related_works': ['https://openalex.org/W4387234050', 'https://openalex.org/W3175383815', 'https://openalex.org/W2468892893', 'https://openalex.org/W227728849', 'https://openalex.org/W2109455664', 'https://openalex.org/W2024846833', 'https://openalex.org/W2012570195', 'https://openalex.org/W1990584803', 'https://openalex.org/W1978885095', 'https://openalex.org/W1968786460'], 'abstract_inverted_index': {'Initiation': [0], 'of': [1, 3, 32, 52, 59, 91, 103, 116, 131], 'translation': [2, 27, 90, 132], 'hepatitis': [4], 'C': [5], 'virus': [6, 11], 'and': [7, 29, 73, 87, 89, 106, 128], 'classical': [8], 'swine': [9], 'fever': [10], 'mRNAs': [12, 77, 93], 'results': [13], 'from': [14, 25], 'internal': [15, 20], 'ribosomal': [16, 21, 34, 65, 111], 'entry.': [17], 'We': [18], 'reconstituted': [19], 'entry': [22], 'in': [23, 63, 68, 114, 134], 'vitro': [24], 'purified': [26], 'components': [28], 'monitored': [30], 'assembly': [31], '48S': [33, 117], 'preinitiation': [35, 118], 'complexes': [36, 45, 112], 'by': [37, 97], 'toe-printing.': [38], 'Ribosomal': [39, 71], 'subunits': [40], '(40S)': [41], 'formed': [42], 'stable': [43], 'binary': [44, 69, 110], 'on': [46, 75], 'both': [47], 'mRNAs.': [48], 'The': [49, 120], 'complex': [50], 'structure': [51], 'these': [53, 76, 92, 109], 'RNAs': [54], 'determined': [55], 'the': [56, 60, 64, 81, 129], 'correct': [57], 'positioning': [58, 74], 'initiation': [61, 82, 126, 133], 'codon': [62], '"P"': [66], 'site': [67], 'complexes.': [70, 119], 'binding': [72], 'did': [78], 'not': [79, 95], 'require': [80], 'factors': [83], 'eIF3,': [84], 'eIF4A,': [85], 'eIF4B,': [86], 'eIF4F': [88], 'was': [94], 'inhibited': [96], 'a': [98], 'trans-dominant': [99], 'eIF4A': [100], 'mutant.': [101], 'Addition': [102], 'Met-tRNAiMet,': [104], 'eIF2,': [105], 'GTP': [107], 'to': [108], 'resulted': [113], 'formation': [115], 'striking': [121], 'similarities': [122], 'between': [123], 'this': [124], 'eukaryotic': [125], 'mechanism': [127, 130], 'prokaryotes': [135], 'are': [136], 'discussed.': [137]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2104947461', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 7}, {'year': 2022, 'cited_by_count': 8}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 15}, {'year': 2019, 'cited_by_count': 14}, {'year': 2018, 'cited_by_count': 24}, {'year': 2017, 'cited_by_count': 20}, {'year': 2016, 'cited_by_count': 15}, {'year': 2015, 'cited_by_count': 31}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 25}, {'year': 2012, 'cited_by_count': 27}], 'updated_date': '2024-12-13T17:24:54.351564', 'created_date': '2016-06-24'}