Publication Information

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'https://openalex.org/W2023322988', 'https://openalex.org/W2013332593', 'https://openalex.org/W1992513963'], 'abstract_inverted_index': {'Insulin': [0, 176, 200, 376], 'stimulates': [1, 201], 'glucose': [2, 202, 435, 481, 601, 2442, 3584, 3586, 3602, 3607], 'transporter': [3, 203], '(GLUT)': [4, 204], '4': [5, 95, 146, 188, 205, 295, 346, 388, 966, 986, 1121, 1519, 1609, 1652, 1689, 2182, 2227, 2886, 2907, 3026, 3049, 3064, 3241, 3257, 3273, 3279, 3455, 4169, 4206, 4245, 4331, 4367, 4388, 4401], 'vesicle': [6, 206, 446, 492, 643, 667, 677, 681, 1363, 1593, 1640, 4128], 'translocation': [7, 73, 207, 273, 424, 626, 756, 997, 1620, 1666, 3949, 4097], 'from': [8, 186, 208, 386, 1827, 1838, 1848, 1861, 1871, 1878, 1889, 2073, 2164, 2186, 2428, 3087, 3121, 3247, 3438, 3811, 3861, 4002, 4100, 4131], 'intracellular': [9, 209, 411, 428, 3786], 'storage': [10, 210], 'sites': [11, 211, 1928, 1953, 2039, 2055, 2079, 2108, 2142, 2217, 2237, 2295, 2321, 2410], 'to': [12, 46, 74, 91, 105, 116, 151, 173, 193, 212, 246, 274, 291, 305, 316, 351, 373, 393, 404, 523, 926, 1210, 1347, 1506, 1607, 1621, 1820, 1934, 2056, 2121, 2206, 2323, 2366, 2485, 2519, 2619, 2621, 2637, 2717, 3066, 3165, 3171, 3297, 3305, 3343, 3374, 3514, 3711, 3718, 3792, 3807, 3940, 3987, 3994, 4055, 4105, 4124, 4164, 4175, 4230, 4326], 'the': [13, 35, 42, 61, 66, 75, 97, 117, 152, 162, 169, 182, 213, 235, 242, 261, 266, 275, 297, 317, 352, 362, 369, 382, 423, 465, 511, 524, 580, 584, 587, 597, 637, 663, 670, 676, 690, 702, 714, 723, 732, 921, 927, 990, 1113, 1116, 1125, 1204, 1211, 1429, 1440, 1581, 1588, 1622, 1650, 1668, 1673, 1805, 1821, 1900, 1917, 1925, 1930, 1949, 1955, 2025, 2035, 2052, 2069, 2074, 2104, 2112, 2122, 2133, 2144, 2155, 2160, 2171, 2176, 2199, 2208, 2213, 2233, 2272, 2292, 2325, 2330, 2341, 2347, 2355, 2368, 2371, 2385, 2414, 2429, 2481, 2500, 2527, 2615, 2653, 2671, 2687, 2694, 2706, 2910, 2936, 3006, 3038, 3068, 3085, 3088, 3122, 3181, 3248, 3353, 3365, 3378, 3402, 3407, 3414, 3422, 3427, 3434, 3439, 3448, 3463, 3468, 3478, 3496, 3507, 3516, 3521, 3526, 3614, 3685, 3696, 3702, 3713, 3719, 3734, 3739, 3767, 3785, 3819, 3822, 3826, 3846, 3862, 3878, 3883, 3903, 3912, 3918, 3931, 3941, 3996, 4006, 4013, 4031, 4061, 4101, 4106, 4125, 4132, 4176, 4190, 4231, 4363, 4382, 4413], 'plasma': [14, 76, 118, 153, 196, 214, 276, 318, 353, 396, 525, 591, 725, 928, 969, 1350, 1623, 2690, 2734, 2833, 2850, 3078, 3116, 3854, 3919, 3942, 4032, 4107, 4177, 4232, 4240], 'membrane': [15, 77, 119, 197, 215, 277, 319, 397, 451, 497, 526, 692, 696, 929, 970, 1351, 2691, 2735, 2809, 2812, 2834, 2851, 2889, 2931, 3079, 3117, 3855, 3920, 3943, 4033, 4108, 4178, 4226, 4233], 'in': [16, 96, 138, 148, 216, 296, 338, 348, 422, 590, 603, 634, 645, 662, 675, 713, 908, 1356, 1362, 1435, 1586, 1615, 1646, 1661, 1667, 1679, 1922, 2230, 2381, 2437, 2460, 2511, 2558, 2789, 2823, 2844, 2909, 2970, 3094, 3139, 3180, 3193, 3447, 3506, 3701, 3716, 3750, 3775, 3790, 3799, 3825, 3845, 3882, 3896, 3902, 3911, 3917, 3930, 4011, 4060, 4093, 4189], '3T3L1': [17, 217, 1616, 2424, 2964, 3812], 'adipocytes': [18, 218, 1617, 2496, 2646, 2659, 2707, 2727, 2965, 3813], 'through': [19, 219, 3008], 'a': [20, 31, 139, 220, 231, 339, 418, 746, 909, 1659, 1680, 1750, 1936, 1974, 2359, 2376, 2512, 2650, 2806, 2919, 3009, 3101, 3283, 3398, 3451, 3565, 3619, 3727, 3776, 3874, 3897, 4094, 4181, 4386, 4423], 'VAMP2-': [21, 221], 'and': [22, 71, 120, 189, 222, 271, 320, 389, 415, 425, 606, 704, 717, 734, 738, 987, 1122, 1137, 1218, 1353, 1374, 1444, 1509, 1610, 1671, 1687, 1790, 1813, 1854, 1882, 1951, 1981, 2031, 2037, 2049, 2062, 2084, 2101, 2106, 2140, 2173, 2192, 2201, 2215, 2235, 2245, 2269, 2289, 2298, 2312, 2374, 2396, 2398, 2403, 2408, 2435, 2443, 2450, 2474, 2490, 2508, 2571, 2585, 2629, 2664, 2715, 2725, 2733, 2800, 2803, 2821, 2855, 2923, 2962, 2968, 2981, 2996, 3054, 3072, 3125, 3142, 3175, 3308, 3364, 3413, 3433, 3460, 3477, 3483, 3511, 3519, 3528, 3534, 3542, 3552, 3559, 3590, 3593, 3609, 3646, 3656, 3742, 3753, 3760, 3769, 3794, 3839, 3853, 3990, 3999, 4017, 4027, 4170, 4195, 4329, 4374], 'syntaxin': [23, 47, 94, 145, 174, 187, 223, 247, 294, 345, 374, 387, 965, 985, 1120, 1447, 1518, 1608, 1688, 2181, 2226, 3272, 4168, 4205, 4244, 4327, 4330, 4366, 4387, 4428], '4-dependent': [24, 224], 'mechanism.': [25, 225], 'We': [26, 226], 'have': [27, 227, 707, 982, 1578, 3873, 4319], 'observed': [28, 228], 'that': [29, 159, 229, 359, 710, 962, 1108, 1366, 1600, 1675, 3691, 4044, 4321], 'Munc18c,': [30, 55, 58, 230, 255, 258, 4369], 'mammalian': [32, 232, 1205], 'homolog': [33, 233], 'of': [34, 44, 57, 69, 131, 164, 171, 184, 234, 244, 257, 269, 331, 364, 371, 384, 402, 427, 599, 627, 641, 665, 672, 701, 719, 742, 745, 904, 912, 924, 1115, 1127, 1135, 1442, 1584, 1591, 1613, 1649, 1682, 1749, 1797, 1808, 1929, 1954, 1973, 2040, 2068, 2080, 2099, 2109, 2114, 2143, 2159, 2175, 2218, 2225, 2238, 2243, 2275, 2296, 2310, 2329, 2340, 2370, 2384, 2413, 2506, 2591, 2652, 2670, 2677, 2683, 2689, 2701, 2875, 2921, 3037, 3269, 3355, 3377, 3382, 3386, 3390, 3397, 3401, 3429, 3450, 3471, 3495, 3509, 3621, 3626, 3629, 3684, 3729, 3766, 3780, 3788, 3821, 3880, 3899, 3914, 3928, 3946, 4009, 4098, 4185, 4203, 4365, 4385], 'yeast': [36, 236, 2348, 3472, 3517, 4372], 'syntaxin-binding': [37, 237], 'protein': [38, 238, 594, 673, 1940, 1944, 3146, 3287, 3692, 3715, 3745, 3824, 3842, 3901, 3916], 'n-Sec1p,': [39, 239], 'competed': [40, 240], 'for': [41, 54, 241, 254, 596, 680, 694, 994, 1371, 1604, 1630, 1964, 2210, 2354, 2392, 2401, 2421, 2499, 2515, 2626, 2633, 2681, 2719, 2826, 2838, 2861, 2882, 2906, 3022, 3045, 3060, 3106, 3112, 3131, 3144, 3237, 3253, 3275, 3289, 3595, 3682, 3690, 4045, 4225], 'binding': [43, 170, 198, 243, 370, 398, 401, 1606, 3380, 4317, 4391], 'VAMP2': [45, 172, 245, 372, 733, 748, 1109, 1605, 1789, 1809, 2244, 2402, 3989, 4099, 4120, 4421], '4.': [48, 175, 248, 375], 'Consistent': [49, 249], 'with': [50, 93, 144, 250, 293, 344, 636, 684, 722, 730, 1119, 1344, 1446, 1520, 1658, 1672, 1799, 2111, 2563, 2588, 2639, 2667, 2698, 2730, 2760, 2768, 2805, 2818, 2857, 2870, 2896, 2899, 2915, 2918, 3177, 3266, 3286, 3462, 3536, 3544, 3672, 3733, 3737, 3908, 3937, 4030, 4050, 4119, 4238, 4368, 4395, 4404, 4412, 4427], 'an': [51, 194, 251, 394, 1647, 2115, 3194, 3387, 3624, 3909], 'inhibitory': [52, 252, 751], 'function': [53, 253, 1376], 'expression': [56, 130, 256, 330, 744, 1612, 3660, 3683, 3765], 'but': [59, 259, 917, 1514, 2154, 3857, 4410], 'not': [60, 124, 260, 324, 919, 3872, 4219, 4411], 'related': [62, 262, 4414], 'Munc18b': [63, 263, 1508, 2090, 2123, 4415], 'isoform,': [64, 264], 'prevented': [65, 265], 'insulin': [67, 108, 127, 267, 308, 327, 403, 467, 513, 922, 1589, 1643, 1676, 2520, 2529, 3834, 3870, 3893, 4090, 4210], 'stimulation': [68, 268, 923, 1590, 1644, 1677, 2638, 3894, 4091, 4211], 'GLUT4': [70, 270, 429, 593, 720, 727, 755, 913, 925, 996, 1592, 1619, 1665, 1686, 1920, 2871, 3793, 3801, 3823, 3841, 3881, 3900, 3915, 3929, 3948, 4127], 'IRAP/vp165': [72, 272, 2161], 'without': [78, 278], 'any': [79, 279, 4221], 'significant': [80, 280, 3875, 4201], 'effect': [81, 281, 1637, 3876], 'on': [82, 282, 2710, 2829, 3167, 3299, 3601, 3606, 3613, 3877], 'GLUT1': [83, 283, 581, 1639, 2136, 2878], 'trafficking.': [84, 284, 1641], 'As': [85, 285], 'expected,': [86, 286], 'overexpressed': [87, 287], 'Munc18c': [88, 112, 160, 185, 192, 288, 312, 360, 385, 392, 1510, 1516, 1585, 1601, 1614, 1626, 1663, 1683, 1742, 1965, 3771, 3789, 4171, 4186, 4208, 4217, 4322, 4405], 'was': [89, 113, 123, 289, 313, 323, 1628, 1635, 1745, 1825, 1836, 1846, 1869, 1913, 1945, 1966, 2022, 2047, 2092, 2129, 2149, 2184, 2228, 2280, 2303, 2336, 2352, 2364, 2379, 2483, 3033, 3052, 3081, 3119, 3245, 3264, 3340, 3456, 3512, 3639, 3670, 3709, 3724, 3831, 3843, 3858, 4040, 4187, 4199, 4432], 'found': [90, 104, 290, 304, 4188], 'co-immunoprecipitate': [92, 292], 'basal': [98, 298, 1669], 'state.': [99, 299], 'However,': [100, 300, 4197], 'these': [101, 156, 301, 356, 628, 1103, 1357, 1367, 1575, 4165], 'complexes': [102, 302, 674, 688], 'were': [103, 303, 1691, 1793, 1859, 1876, 1887, 1896, 2064, 2204, 2247, 2405, 2426, 2456, 2497, 2509, 2532, 2556, 2578, 2617, 2630, 2647, 2660, 2696, 2708, 2728, 2737, 2758, 2787, 2814, 2836, 2853, 2891, 2933, 2966, 3002, 3015, 3137, 3163, 3189, 3295, 3531, 3576, 3617, 3651, 3680, 3755, 3992, 4000, 4172], 'dissociate': [106, 306], 'upon': [107, 307, 1574, 1638], 'stimulation.': [109, 128, 309, 328, 2521], 'Furthermore,': [110, 310, 1642, 4089], 'endogenous': [111, 311], 'predominantly': [114, 314, 1433, 4122], 'localized': [115, 315, 3993, 4054, 4123, 4174], 'its': [121, 321, 405, 410, 3938, 4228, 4236], 'distribution': [122, 322, 3879], 'altered': [125, 325], 'by': [126, 167, 180, 190, 326, 367, 380, 390, 1111, 1747, 1795, 1915, 1968, 2066, 2094, 2131, 2151, 2282, 2305, 2338, 2458, 2581, 2649, 2741, 2765, 2868, 2925, 2941, 3004, 3035, 3083, 3098, 3191, 3251, 3282, 3303, 3316, 3633, 3663, 3688, 3695, 3726, 3833], 'Although': [129, 329, 573, 956, 3869], 'enhanced': [132, 332, 438, 484], 'green': [133, 333, 439, 485, 1909, 1938], 'fluorescent': [134, 334, 440, 486, 1910, 1939], 'protein-Munc18c': [135, 335], 'primarily': [136, 336, 4173], 'resulted': [137, 147, 337, 347, 907, 3895, 4092], 'dispersed': [140, 340], 'cytosolic': [141, 341], 'distribution,': [142, 342], 'co-expression': [143, 343], 'increased': [149, 349, 1611], 'localization': [150, 350, 2362, 2369, 2388, 2417, 3405, 3787, 4229], 'membrane.': [154, 354, 726, 1624], 'Together,': [155, 355], 'data': [157, 357, 1104, 1655, 4116], 'suggest': [158, 358], 'inhibits': [161, 361, 1439, 1618, 1664], 'docking/fusion': [163, 363], 'GLUT4-containing': [165, 365, 629, 1117, 1631], 'vesicles': [166, 366, 522, 630, 721, 728, 914, 1118], 'blocking': [168, 368, 975], 'relieves': [177, 377], 'this': [178, 378, 1596], 'inhibition': [179, 379, 1627], 'inducing': [181, 381], 'dissociation': [183, 383], 'sequestering': [191, 391], 'alternative': [195, 395], 'site.': [199, 399, 2125], 'The': [400, 624, 659, 1625, 1685, 1741, 1905, 1961, 2020, 2088, 2126, 2146, 2179, 2220, 2240, 2333, 2785, 2831, 2848, 3028, 3076, 3115, 3292, 3310, 3369, 3392, 3418, 3474, 3488, 3499, 3705, 3926], 'heterotetrameric': [406], 'integral-membrane': [407], 'receptor': [408, 687, 2530], 'activates': [409], 'tyrosine': [412], 'kinase': [413], 'domain': [414, 2222, 3381, 4392, 4407], 'thereby': [416], 'triggers': [417], 'signaling': [419], 'cascade': [420], 'resulting': [421, 3039], 'fusion': [426, 718, 1802, 1943, 3686, 3721, 3741, 4393, 4408], '1The': [430, 476], 'abbreviations': [431, 477], 'used': [432, 478, 2205, 2498, 3341, 3373, 3457, 3804, 4371], 'are:': [433, 479], 'GLUT,': [434, 480], 'transporter;': [436, 482], 'eGFP,': [437, 483], 'protein;': [441, 487], 'IRAP/vp165,': [442, 488], 'insulin-responsive': [443, 489, 4126], 'aminopeptidase;': [444, 490], 'v-SNARE,': [445, 491], 'SNAP': [447, 452, 493, 498, 682, 697], 'receptor;': [448, 453, 468, 494, 499, 514], 't-SNARE,': [449, 495], 'target': [450, 496, 691, 695], 'DMEM,': [454, 500, 2486], "Dulbecco's": [455, 501], 'modified': [456, 502, 3710], "Eagle's": [457, 503, 2560], 'medium;': [458, 504], 'CHO/IR,': [459, 505], 'Chinese': [460, 506, 2522], 'hamster': [461, 507, 2523], 'ovary': [462, 508, 2524], 'cells': [463, 509, 2455, 2525, 2555, 2577, 2616, 2695, 2786, 3007], 'expressing': [464, 510, 2526], 'human': [466, 512, 2528], 'PAGE,': [469, 515], 'polyacrylamide': [470, 516], 'gel': [471, 517], 'electrophoresis;': [472, 518], 'PBS,': [473, 519, 2732, 2897, 2916], 'phosphate-buffered': [474, 520], 'saline.': [475], 'saline.isoform-containing': [521], '(1James': [527], 'D.E.': [528, 651, 882, 939, 1085, 1528, 1556, 2748, 2950, 3966, 4077, 4145, 4251, 4343], 'Piper': [529, 2942], 'R.C.': [530, 2946], 'Slot': [531, 4072], 'J.W.': [532, 4073], 'Trends': [533], 'Cell': [534, 3000, 4079], 'Biol.': [535, 764, 788, 864, 884, 941, 1006, 1030, 1087, 1310, 1489, 1530, 1558, 1704, 1726, 2260, 2545, 2602, 4080, 4147, 4253, 4273, 4345], '1994;': [536, 1256, 1277, 1416, 1462, 2604], '4:': [537], '120-126Abstract': [538], 'Full': [539, 769, 793, 795, 889, 891, 946, 948, 1092, 1094, 1169, 1315, 1317, 1419, 1494, 1496, 1535, 1537, 1563, 1565, 1731, 1733, 2607, 3332, 4152, 4154, 4258, 4260, 4278, 4280, 4305, 4307, 4350, 4352], 'Text': [540, 770, 794, 796, 890, 892, 947, 949, 1093, 1095, 1170, 1316, 1318, 1420, 1495, 1497, 1536, 1538, 1564, 1566, 1732, 1734, 2608, 3333, 4153, 4155, 4259, 4261, 4279, 4281, 4306, 4308, 4351, 4353], 'PDF': [541, 771, 797, 893, 950, 1096, 1171, 1319, 1421, 1498, 1539, 1567, 1735, 2609, 3334, 4156, 4262, 4282, 4309, 4354], 'PubMed': [542, 555, 570, 619, 656, 772, 798, 825, 851, 868, 894, 951, 1010, 1035, 1067, 1097, 1158, 1172, 1183, 1197, 1233, 1259, 1280, 1320, 1400, 1422, 1465, 1499, 1540, 1568, 1708, 1736, 1784, 2015, 2264, 2549, 2610, 2957, 3157, 3335, 3958, 3971, 3983, 4084, 4157, 4263, 4283, 4310, 4355], 'Scopus': [543, 556, 620, 799, 826, 852, 869, 895, 952, 1011, 1036, 1068, 1098, 1159, 1173, 1184, 1198, 1234, 1260, 1281, 1321, 1401, 1423, 1466, 1500, 1541, 1569, 1709, 1737, 1785, 2016, 2265, 2550, 3158, 3336, 3959, 4085, 4158, 4264, 4284, 4311, 4356], '(95)': [544, 1099], 'Google': [545, 558, 571, 622, 657, 773, 801, 828, 854, 871, 897, 954, 1013, 1038, 1070, 1100, 1161, 1175, 1186, 1200, 1236, 1262, 1283, 1323, 1339, 1403, 1425, 1468, 1502, 1543, 1571, 1711, 1739, 1787, 2018, 2267, 2552, 2611, 2755, 2958, 3160, 3338, 3961, 3972, 3984, 4087, 4160, 4266, 4286, 4313, 4358], 'Scholar,': [546, 559, 774, 802, 829, 855, 872, 1014, 1039, 1071, 1162, 1176, 1187, 1237, 1263, 1284, 1324, 1404, 1469, 1544, 1712, 3962, 4267, 4287], '2Czech': [547], 'M.P.': [548, 3951], 'Annu.': [549, 613, 3952], 'Rev.': [550, 614, 1193, 3953], 'Nutr.': [551, 3954], '1995;': [552, 790, 1166, 1180, 1312, 1532, 2546, 3955, 4255], '15:': [553, 2547, 3956], '441-471Crossref': [554, 3957], '(96)': [557, 3960], '3Kandror': [560], 'K.V.': [561, 3974], 'Pilch': [562, 3975], 'P.F.': [563, 3976], 'Am.': [564, 2749, 2951, 3977], 'J.': [565, 763, 787, 883, 940, 1049, 1086, 1245, 1265, 1288, 1304, 1309, 1390, 1395, 1412, 1450, 1488, 1529, 1557, 1725, 1766, 1997, 2542, 2600, 2601, 2750, 2952, 3321, 3978, 4069, 4078, 4146, 4252, 4272, 4344], 'Physiol.': [566, 1192, 2751, 2953, 3979], '1996;': [567, 616, 822, 848, 1032, 1194, 1491, 3980, 4081], '271:': [568, 1492, 3981], 'E1-E14Crossref': [569, 3982], 'Scholar).': [572, 623, 658, 898, 955, 1101, 1201, 1340, 1426, 1503, 1572, 1740, 1788, 2019, 2553, 2612, 2756, 2959, 3161, 3985, 4088, 4161, 4314, 4359], 'most': [574], 'cell': [575, 585, 3186, 3260, 3828], 'types': [576], 'also': [577, 1132], 'constitutively': [578], 'express': [579, 3712], 'isoform': [582, 1431, 4416], 'at': [583, 689, 2447, 2568, 2642, 2841, 2864, 2885, 3018, 3025, 3041, 3048, 3056, 3063, 3108, 3127, 3240, 3256, 3278, 3572], 'surface,': [586], 'insulin-stimulated': [588, 625, 754, 995, 2726, 2963, 3800, 3947], 'increase': [589, 3910], 'membrane-associated': [592], 'accounts': [595], 'majority': [598], 'post-prandial': [600], 'disposal': [602], 'both': [604, 731, 4012], 'muscle': [605], 'adipose': [607, 1976], 'tissue': [608, 2623, 2712], '(4Olson': [609], 'A.L.': [610, 857, 999, 1697, 1718, 2253], 'Pessin': [611, 860, 1002, 1700, 1723, 2256, 2541, 2599], 'J.E.': [612, 861, 1003, 1153, 1701, 1724, 2257], 'Nutri.': [615], '16:': [617], '235-256Crossref': [618], '(387)': [621], 'has': [631], 'several': [632, 700, 1133, 3795, 4396], 'features': [633], 'common': [635], 'regulated': [638], 'exocytosis': [639], 'pathway': [640], 'synaptic': [642, 666, 1128], 'trafficking': [644], 'neurotransmitter': [646], 'release': [647], '(5Rea': [648], 'S.': [649, 780, 820, 835, 841, 1041, 1073, 1077, 1149, 1254, 1275, 1380, 1386, 1460, 1526, 1550, 1758, 1989, 2538, 3964, 4067, 4249, 4337], 'James': [650, 881, 938, 1084, 1527, 1555, 2747, 2949, 3965, 4076, 4144, 4250, 4342], 'Diabetes.': [652, 3967], '1997;': [653, 865, 1007, 1064, 1560, 1705, 1728, 1781, 2012, 2261, 3968, 4275, 4302, 4347], '46:': [654, 3969], '1667-1677Crossref': [655, 3970], 'machinery': [660], 'involved': [661, 3798], 'regulation': [664], 'priming/docking/fusion': [668], 'entails': [669], 'pairing': [671], 'compartment': [678], '(v-SNAREs,': [679], 'receptors)': [683], 'their': [685, 1348], 'cognate': [686, 1349], '(t-SNAREs,': [693], 'receptors).': [698], 'Recently,': [699], 'v-': [703, 1136, 1373], 't-SNARE': [705, 971, 992, 1138, 1375], 'proteins': [706, 993, 1207, 1222, 1342, 1368, 1803, 3687, 3772, 3797, 4242], 'been': [708], 'identified': [709], 'specifically': [711, 1602, 4402], 'participate': [712], 'insulin-regulated': [715], 'docking': [716], 'adipocyte': [724], 'co-purify': [729], 'VAMP3': [735, 916, 1791, 1814, 2246, 2404, 3991, 4010, 4051, 4111], 'v-SNARE': [736], 'isoforms': [737], 'specific': [739, 960, 1629, 4424], 'proteolytic': [740], 'cleavage': [741], 'VAMP2,': [743], 'dominant-interfering': [747, 977], 'mutant': [749], 'or': [750, 967, 1899, 2877, 3359, 3362, 3694, 4207], 'peptides': [752], 'impairs': [753], '(6Cain': [757], 'C.C.': [758], 'Trimble': [759], 'W.S.': [760], 'Lienhard': [761], 'G.E.': [762], 'Chem.': [765, 789, 885, 942, 1088, 1311, 1490, 1531, 1559, 1727, 2603, 4148, 4254, 4274, 4346], '1992;': [766, 1397, 2752], '267:': [767], '11681-11684Abstract': [768], '7Volchuk': [775], 'A.': [776, 786, 806, 814, 821, 876, 933, 1016, 1028, 1255, 1276, 1326, 1392, 1461, 4139], 'Sargeant': [777], 'R.': [778, 1378, 3327], 'Sumitani': [779], 'Liu': [781, 1021], 'Z.': [782, 1022, 1332, 1334], 'He': [783, 1023], 'L.': [784, 810, 1024], 'Klip': [785, 813, 1027], '270:': [791, 1313, 1533, 4256], '8233-8240Abstract': [792], '(121)': [800], '8Cheatham': [803], 'B.': [804], 'Volchuk': [805], 'Kahn': [807], 'C.R.': [808], 'Wang': [809, 1017], 'Rhodes': [811], 'C.J.': [812], 'Proc.': [815, 1249], 'Natl.': [816, 1250], 'Acad.': [817, 1251], 'Sci.': [818, 1252], 'U.': [819, 1253, 1274, 1459], '93:': [823], '15169-15173Crossref': [824], '(162)': [827], '9Tamori': [830], 'Y.': [831, 837, 1043, 1224, 1298, 1306, 1308, 1382, 1471, 1481, 1487, 1760, 1991], 'Hashiramoto': [832], 'M.': [833, 839, 843, 1045, 1059, 1145, 1243, 1300, 1302, 1762, 1776, 1993, 2007, 4269, 4289], 'Araki': [834], 'Kamata': [836], 'Takahashi': [838], 'Kozaki': [840], 'Kasuga': [842, 1058, 1775, 2006], 'Biochem.': [844, 1060, 1777, 2008, 3153], 'Biophys.': [845, 1061, 1778, 2009], 'Res.': [846, 1062, 1779, 2010], 'Commun.': [847, 1063, 1780, 2011], '220:': [849], '740-745Crossref': [850], '(61)': [853], '10Olson': [856], 'Knight': [858, 1000, 1698, 2254], 'J.B.': [859, 1001, 1699, 2255], 'Mol.': [862, 1004, 1029, 1702, 2258, 2543], 'Cell.': [863, 1005, 1031, 1703, 2259, 2544, 3328], '17:': [866, 1008, 1706, 2262], '2425-2435Crossref': [867, 1009, 1707, 2263], '(208)': [870, 1012, 1424, 1710, 2266], '11Martin': [873], 'L.B.': [874, 931, 1075, 4137], 'Shewan': [875, 932, 4138], 'Millar': [877, 934, 4140], 'C.A.': [878, 935, 1226, 4141], 'Gould': [879, 936, 4074, 4142], 'G.W.': [880, 937, 4075, 4143], '1998;': [886, 943, 1089, 4149], '273:': [887, 944, 1090, 4150], '1444-1452Abstract': [888, 945, 4151], '(126)': [896, 953, 1037, 4159], 'In': [899, 1124, 1202, 1427, 1504, 1595, 2686, 4162, 4315], 'addition,': [900], 'transferrin-horseradish': [901], 'peroxidase': [902], 'ablation': [903], 'recycling': [905, 4133], 'endosomes': [906], 'selective': [910, 3545], 'loss': [911, 3728, 3779, 3898], 'containing': [915, 1804, 2439, 2462, 2985, 3548, 3582], 'did': [918, 3871], 'prevent': [920], '(11Martin': [930, 4136], 'there': [957, 1130, 1634, 4198, 4431], 'are': [958, 1131, 1208, 1369, 1511, 1656, 4058, 4117], 'no': [959, 1636, 3444, 3502, 3604, 3743, 4200, 4433], 'endoproteases': [961], 'cleave': [963], 'either': [964, 4204], 'SNAP23/Syndet': [968, 988], 'proteins,': [972, 4167], 'studies': [973], 'using': [974, 1979, 2317, 2935, 3666], 'antibodies,': [976], 'mutants,': [978], 'and/or': [979], 'peptide': [980, 1753], 'inhibitors': [981], 'strongly': [983], 'implicated': [984], 'as': [989, 1633, 1693, 1754, 1985, 2249, 2344, 2534, 2594, 2739, 3458, 3540, 3623, 3631, 3641, 3653, 3661, 3668, 3757, 3763], 'required': [991], '(10Olson': [998, 1696, 2252], '12Volchuk': [1015], 'Q.': [1018], 'Ewart': [1019], 'H.S.': [1020, 1722], 'Bennett': [1025], 'M.K.': [1026], '7:': [1033], '1075-1082Crossref': [1034], '13Araki': [1040], 'Tamori': [1042, 1759, 1990], 'Kawanishi': [1044, 1761, 1992], 'Shinoda': [1046, 1763, 1994], 'H.': [1047, 1051, 1055, 1147, 1286, 1292, 1477, 1764, 1768, 1772, 1995, 1999, 2003, 3325, 4294], 'Masugi': [1048, 1765, 1996], 'Mori': [1050, 1767, 1998], 'Niki': [1052, 1769, 2000], 'T.': [1053, 1057, 1081, 1141, 1290, 1294, 1384, 1473, 1479, 1770, 1774, 2001, 2005], 'Okazawa': [1054, 1771, 2002], 'Kubota': [1056, 1773, 2004], '234:': [1065, 1782, 2013], '257-262Crossref': [1066, 1783, 2014], '(85)': [1069, 1786, 2017], '14Rea': [1072], 'Martin': [1074], 'McIntosh': [1076, 1525, 1549, 4248, 4336], 'Macaulay': [1078, 1547, 4334], 'S.L.': [1079, 1548, 4335], 'Ramsdale': [1080], 'Baldini': [1082], 'G.': [1083], '18784-18792Abstract': [1091], 'Thus,': [1102], 'provide': [1105], 'compelling': [1106], 'evidence': [1107], 'functions': [1110], 'directing': [1112], 'association': [1114, 1441], 'SNAP23/Syndet.': [1123], 'case': [1126, 2688], 'transmission,': [1129], 'modulators': [1134], 'interactions': [1139, 3345], '(15Sollner': [1140], 'Whiteheart': [1142, 2308], 'S.W.': [1143], 'Brunner': [1144], 'Erdjument-Bromage': [1146], 'Geromanos': [1148], 'Tempst': [1150], 'P.': [1151, 1248], 'Rothman': [1152], 'Nature.': [1154, 1179, 1229], '1993;': [1155, 1230, 1336, 3329], '362:': [1156], '318-324Crossref': [1157], '(2616)': [1160], '16Scheller': [1163], 'R.H.': [1164, 1191, 1269, 1454, 1485], 'Neuron.': [1165, 1415, 4301], '14:': [1167], '893-897Abstract': [1168], '(196)': [1174], '17Sudhof': [1177], 'T.C.': [1178, 1228, 1483, 4271, 4300], '375:': [1181], '645-653Crossref': [1182], '(1767)': [1185], '18Calakos': [1188], 'N.': [1189, 1328, 1330], 'Scheller': [1190, 1268, 1453, 1484, 2189], '76:': [1195], '1-29Crossref': [1196], '(306)': [1199], 'particular,': [1203], 'Munc18': [1206], 'homologous': [1209], 'Saccharomyces': [1212], 'cerevisiae': [1213], 'n-Sec1/rbSec1,': [1214], 'Caenorhabditis': [1215], 'elegans': [1216], 'unc18,': [1217], 'Drosophila': [1219], 'melanogaster': [1220], 'Rop': [1221], '(19Hata': [1223], 'Slaughter': [1225], 'Sudhof': [1227, 1482, 4270, 4299], '366:': [1231], '347-351Crossref': [1232], '(590)': [1235], '20Garcia': [1238], 'E.P.': [1239], 'Gatti': [1240], 'E.': [1241, 3323], 'Butler': [1242], 'Burton': [1244], 'De': [1246], 'Camilli': [1247], '91:': [1257, 1278, 1463], '2003-2007Crossref': [1258], '(224)': [1261], '21Pevsner': [1264], 'Hsu': [1266, 1451], 'S.-C.': [1267, 1452], 'Proc': [1270, 1455], 'Natl': [1271, 1456], 'Acad': [1272, 1457], 'Sci': [1273, 1458], '1445-1449Crossref': [1279, 1464], '(353)': [1282, 1467], '22Katagiri': [1285], 'Terasaki': [1287], 'Murata': [1289], 'Ishihara': [1291], 'Ogihara': [1293], 'Inukai': [1295], 'K.': [1296, 1388, 1408, 1475, 2540, 2598], 'Fukushima': [1297], 'Anai': [1299], 'Kikuchi': [1301], 'Miyazaki': [1303], 'Yazaki': [1305], 'Oka': [1307], '4963-4966Abstract': [1314], '(69)': [1322], '23Salzberg': [1325], 'Cohen': [1327], 'Halachmi': [1329], 'Kimchie': [1331], 'Lev': [1333], 'Development.': [1335], '117:': [1337], '1309-1319PubMed': [1338], 'These': [1341, 1654, 4115], 'bind': [1343, 3520, 4325], 'high': [1345, 1521, 3069, 3627, 3850, 3904, 3932, 4018, 4102], 'affinity': [1346, 1522], 'syntaxins,': [1352], 'null': [1354], 'mutations': [1355], 'genes': [1358], 'cause': [1359], 'dramatic': [1360], 'reduction': [1361], 'exocytosis,': [1364], 'suggesting': [1365], 'essential': [1370], 'normal': [1372], '(24Hosono': [1377], 'Hekimi': [1379], 'Kamiya': [1381], 'Sassa': [1383], 'Murakami': [1385], 'Nishiwaki': [1387], 'Miwa': [1389], 'Taketo': [1391], 'Kodaira': [1393], 'K.-I.': [1394], 'Neurochem.': [1396], '58:': [1398], '1517-1525Crossref': [1399], '(152)': [1402], '25Harrison': [1405], 'S.D.': [1406], 'Broadie': [1407], 'van': [1409], 'de': [1410, 4290], 'Goor': [1411], 'Rubin': [1413], 'G.M.': [1414], '13:': [1417], '555-566Abstract': [1418], 'mammals,': [1428], 'Munc18a': [1430], 'is': [1432, 3372, 3491, 3944, 4048], 'expressed': [1434, 1512], 'neurons,': [1436], 'where': [1437], 'it': [1438], 'VAMP1': [1443], 'SNAP25': [1445], '1': [1448, 2469, 2472, 2782, 2801, 2978, 2986, 3221, 3224, 3231, 3838], '(21Pevsner': [1449], '26Fujita': [1470], 'Sasaki': [1472], 'Fukui': [1474], 'Kotani': [1476], 'Kimura': [1478], 'Hata': [1480], 'Takai': [1486], '7265-7268Abstract': [1493], '(230)': [1501], 'contrast': [1505, 4163], 'Munc18a,': [1507], 'ubiquitously': [1513], 'only': [1515, 3738], 'binds': [1517], '(27Tellam': [1523, 4246], 'J.T.': [1524, 1546, 4247, 4333], '5857-5863Abstract': [1534, 4257], '(160)': [1542, 4265], '28Tellam': [1545], 'Hewish': [1551, 4338], 'D.R.': [1552, 4339], 'Ward': [1553, 4340], 'C.W.': [1554, 4341], '272:': [1561, 1729, 4276, 4348], '6179-6186Abstract': [1562, 4349], '(185)': [1570, 4357], 'Based': [1573], 'data,': [1576], 'we': [1577, 1598, 3803, 4370, 4380], 'now': [1579], 'investigated': [1580], 'functional': [1582], 'role': [1583], 'modulating': [1587], 'translocation.': [1594], 'report': [1597], 'demonstrate': [1599], 'competes': [1603], 'vesicles,': [1632], 'results': [1645, 1678, 3774], 'uncoupling': [1648], 'Munc18c-syntaxin': [1651], 'complex.': [1653], 'consistent': [1657, 3671, 4049, 4118], 'model': [1660], 'which': [1662, 3830, 4057], 'state': [1670], 'hypothesis': [1674], 'de-repression': [1681], 'function.': [1684], 'antibodies': [1690, 1792, 3178], 'isolated': [1692, 2849], 'described': [1694, 1755, 1986, 2250, 2535, 2595, 2740, 2940, 3315], 'previously': [1695, 1756, 1987, 2251, 2536, 2596], '29Chen': [1713], 'D.': [1714], 'Elmendorf': [1715], 'J.S.': [1716], 'Olson': [1717], 'Li': [1719], 'X.': [1720], 'Earp': [1721], '27401-27410Abstract': [1730], '(139)': [1738], 'polyclonal': [1743], 'antibody': [1744, 1819, 2872, 2879, 2905, 3274], 'obtained': [1746, 1847, 1860, 1877, 1967, 2163, 2185, 2248, 2533, 2934, 3034, 3082], 'immunization': [1748, 1796], 'carboxyl-terminal': [1751, 1937], 'synthetic': [1752], '(13Araki': [1757, 1988], 'prepared': [1794, 1914, 2738, 3003, 3190], 'sheep': [1798, 3271], 'glutathione': [1800], 'S-transferase': [1801], 'cytoplasmic': [1806, 2221, 2241, 2399], 'domains': [1807, 2242, 2400, 4222], '(amino': [1810, 1815], 'acids': [1811, 1816, 3555], '1–94)': [1812], '1–81).': [1817], 'Monoclonal': [1818], 'Flag': [1822, 2045, 2117, 2377, 2419], 'epitope': [1823, 2046, 2118, 2378, 3416, 3698], '(M2)': [1824], 'purchased': [1826, 1837, 1870, 1888, 2427], 'Eastman': [1828], 'Kodak': [1829], 'Corp.': [1830], 'Lissamine': [1831], 'rhodamine-conjugated': [1832, 2901], 'donkey': [1833, 2859, 2902], 'anti-rabbit': [1834, 2903], 'IgG': [1835], 'Jackson': [1839], 'Immunoresearch': [1840], 'Laboratories': [1841, 1850], '(West': [1842], 'Grove,': [1843], 'PA).': [1844], 'Vectashield': [1845], 'Vector': [1849], '(Burlingame,': [1851], 'CA).': [1852, 1893, 1960], 'Hyperfilm-MP': [1853], 'Enhanced': [1855], 'Chemiluminescent': [1856], '(ECL)': [1857], 'reagent': [1858, 1868, 1897], 'Amersham': [1862], 'Pharmacia': [1863], 'Biotech.': [1864], 'Supersignal': [1865], 'Ultra': [1866], 'ECL': [1867], 'Pierce.': [1872], 'Yeast': [1873, 3523], 'dropout': [1874, 3546], 'media': [1875, 3547, 3616], 'CLONTECH.': [1879], 'Mini-prep': [1880], 'DNA': [1881, 1883, 2209, 2680, 3379, 4390], 'agarose': [1884], 'extraction': [1885], 'kits': [1886], 'Qiagen': [1890], '(Santa': [1891], 'Clarita,': [1892], 'Other': [1894], 'chemicals': [1895], 'grade': [1898], 'best': [1901], 'quality': [1902], 'commercially': [1903], 'available.': [1904], 'pcDNA3': [1906, 1956, 2110], 'GLUT4-eGFP': [1907], '(enhanced': [1908], 'protein)': [1911], 'construct': [1912, 2076, 2128, 2343], 'subcloning': [1916, 2067, 2132, 2211], 'full-length': [1918, 1962, 2089, 2134, 2180], 'rat': [1919, 2135], 'cDNA': [1921, 1963, 2021, 2091, 2137, 2162, 2183, 2279, 2302, 3389], 'frame': [1923, 2231, 2382], 'into': [1924, 1948, 2024, 2034, 2051, 2077, 2103, 2138, 2170, 2212, 2232, 2271, 2291, 2315, 3467], 'HindIII': [1926, 1950, 2172], 'andBamHI': [1927], 'pEGFP': [1931], 'vector': [1932, 1957, 2027, 2335, 3371, 3394, 3466, 3476, 3563, 3708, 3736], '(CLONTECH)': [1933, 1978], 'generate': [1935, 3067, 3375], 'fusion.': [1941], 'This': [1942, 3349, 4047], 'subsequently': [1946, 2032], 'subcloned': [1947, 2033, 2102, 2119, 2229, 2270, 2290, 2313], 'XbaI': [1952], '(Invitrogen,': [1958], 'Carlsbad': [1959], 'polymerase': [1969, 2193], 'chain': [1970, 2194], 'reaction': [1971, 2195], 'amplification': [1972], 'mouse': [1975], 'library': [1977], '5′-': [1980, 2200], '3′-untranslated': [1982, 2202], 'region': [1983, 3437], 'primers': [1984, 2196], 'shuttled': [2023], 'pGEM-T': [2026], '(Promega,': [2028], 'Madison': [2029], 'WI)': [2030], 'NcoI': [2036], 'SalI': [2038], 'pLexA': [2041, 3358], '(CLONTECH).': [2042], 'An': [2043], 'in-frame': [2044, 2116, 2314, 3388], 'synthesized': [2048, 2322], 'inserted': [2050, 2406], 'EcoRI': [2053, 2105, 2141, 2214, 2293], 'andNcoI': [2054], 'create': [2057], 'pLexA-Flag-Munc18c.': [2058], 'Plasmids': [2059], 'pB42AD-Flag-Munc18c,': [2060], 'pcDNA3-Flag-Munc18c,': [2061], 'eGFP-Flag-Munc18c': [2063], 'constructed': [2065, 2150, 2337], 'EcoRI/SalI': [2070], 'fragment': [2071], 'derived': [2072], 'pLexA-Flag-Munc18c': [2075], 'compatible': [2078], 'pB42AD': [2081, 2297, 2316, 2331, 2342, 2356, 3361], '(CLONTECH),': [2082, 2086], 'pcDNA3,': [2083], 'pEGFP-C2': [2085], 'respectively.': [2087, 3487, 3658], 'provided': [2093, 2281, 2304], 'Dr.': [2095, 2165, 2187, 2283, 2306], 'Hideki': [2096], 'Katagiri': [2097], '(University': [2098, 2309], 'Tokyo)': [2100], 'XhoI': [2107, 2174, 2216, 2273, 2409], 'addition': [2113, 3717], 'amino-terminal': [2120], 'start': [2124], 'eGFP-GLUT1': [2127], 'made': [2130, 3532], 'theXhoI': [2139], 'pEGFP-C3.': [2145], 'eGFP-IRAP/vp165': [2147], 'plasmid': [2148, 2592, 2679, 2702, 3480], 'inserting': [2152], 'all': [2153, 3553, 3610, 3995], 'extracellular': [2156], 'residues': [2157], '(1–135)': [2158], 'Steven': [2166], 'Waters': [2167], '(Metabolics,': [2168], 'Inc.)': [2169], 'pEGFP-C3': [2177], 'vector.': [2178, 2332, 3704], 'Richard': [2188], '(Stanford': [2190], 'University)': [2191], 'directed': [2197], 'against': [2198], 'regions': [2203], 'amplify': [2207], 'pcDNA3.': [2219, 2299], '(residues': [2223], '2–274)': [2224], 'BamHI': [2234, 2318], 'NotI': [2236], 'pLexA.': [2239], 'Scholar)': [2268], 'site': [2274, 2328], 'pB42AD.': [2276], 'Full-length': [2277, 2300, 2390], 'SNAP23': [2278], 'Paul': [2284], 'Roche': [2285], '(National': [2286], 'Cancer': [2287], 'Institute)': [2288], 'andXhoI': [2294], 'αSNAP': [2301], 'Sidney': [2307], 'Kentucky)': [2311], 'andApaI': [2319], 'polylinker': [2320], 'extend': [2324], 'multiple': [2326], 'cloning': [2327], 'three-hybrid': [2334, 3735, 4375], 'modification': [2339, 2651], 'follows:': [2345], '1)': [2346], 'Gal1-Gal10': [2349], 'bi-directional': [2350], 'promoter': [2351], 'substituted': [2353], 'promoter,': [2357], '2)': [2358], 'second': [2360, 3284], 'nuclear': [2361, 2387, 2416, 3404], 'sequence': [2363, 2418], 'added': [2365, 2380], 'drive': [2367], '"competitor"': [2372], 'protein,': [2373], '3)': [2375], 'downstream': [2383], 'new': [2386, 2415], 'sequence.': [2389], 'cDNAs': [2391], 'SNAP23,': [2393], 'Flag-Munc18c,': [2394], 'Flag-Munc18b,': [2395], 'αSNAP,': [2397], 'intoEcoRI': [2407], 'created': [2411], '3′': [2412], 'tag': [2420, 3699], 'competitor': [2422, 3714, 3744, 3770], 'cDNAs.': [2423], 'preadipocytes': [2425], 'American': [2430], 'Type': [2431], 'Tissue': [2432], 'Culture': [2433], 'repository': [2434], 'cultured': [2436], 'DMEM': [2438], '25': [2440, 2463, 2487, 2842], 'mm': [2441, 2476, 2488, 2772, 2775, 2780, 2783, 2846, 2974, 2979, 2983, 2987, 3200, 3210, 3214, 3218, 3225], '10%': [2444, 2465, 2491, 2564, 3168, 3207, 3300], 'calf': [2445], 'serum': [2446, 2468, 2567, 2860], '37': [2448, 2569, 2643, 2865], '°C': [2449, 2570, 2843, 3065], '8%': [2451], 'CO2.': [2452, 2573], 'At': [2453], 'confluence,': [2454], 'differentiated': [2457, 2658], 'incubation': [2459, 2869, 3285], 'medium': [2461, 2482, 2514, 2561], 'mmglucose,': [2464], 'fetal': [2466, 2492, 2565], 'bovine': [2467, 2493, 2566], 'μg/ml': [2470, 2991, 2994, 2998, 3229, 3232, 3235], 'insulin,': [2471], 'mmdexamethasone,': [2473], '0.5': [2475], 'isobutyl-1-methylxanthine.': [2477], 'After': [2478, 3569], 'four': [2479, 3580], 'days': [2480, 2503, 3571], 'changed': [2484], 'glucose,': [2489, 3549], 'serum.': [2494], 'Differentiated': [2495, 2645], 'experiments': [2501], '12': [2502], 'after': [2504], 'initiation': [2505], 'differentiation': [2507], 'placed': [2510, 2788], 'serum-depleted': [2513], '3': [2516, 3891], 'h': [2517, 2628, 2635, 2721, 2884, 2908, 3277], 'prior': [2518, 2636], '(CHO/IR)': [2531], '(30Waters': [2537], 'Yamauchi': [2539], '2791-2799Crossref': [2548], '(106)': [2551], 'CHO/IR': [2554, 2576], 'incubated': [2557, 2898], 'minimal': [2559, 3435], 'supplemented': [2562], '5%': [2572, 2858], 'Fully': [2574], 'confluent': [2575], 'transiently': [2579], 'transfected': [2580, 2648], 'electroporation': [2582, 2654], '(0.34': [2583], 'kV': [2584, 2663], '960': [2586, 2665], 'microfarads)': [2587, 2666], '40': [2589], 'μg': [2590, 2669, 2676, 2700, 3268], 'DNA/cuvette': [2593], '(31Yamauchi': [2597], '269:': [2605], '31107-31114Abstract': [2606], 'Following': [2613, 2704], 'electroporation,': [2614, 2705], 'allowed': [2618, 2716], 'adhere': [2620], '10-cm': [2622], 'culture': [2624, 2713], 'dishes': [2625], '40–48': [2627, 2720], 'then': [2631, 2892, 3016], 'serum-starved': [2632], '6': [2634], '100': [2640, 2796, 2845], 'nminsulin': [2641], '°C.': [2644, 2887, 3027, 3050, 3242, 3258], 'method.': [2655], 'Briefly,': [2656, 2960], 'fully': [2657], 'electroporated': [2661, 2697], '(0.16': [2662], '50': [2668, 3209, 3645], 'eGFP-tagged': [2672], 'plasmids': [2673, 3530], 'plus': [2674, 2795], '200': [2675], 'additional': [2678], 'analysis': [2682, 3817], 'eGFP': [2684], 'fluorescence.': [2685], 'sheet': [2692], 'analysis,': [2693], '600': [2699], 'DNA.': [2703], 're-plated': [2709], 'collagen-coated': [2711], 'plates': [2714, 3575, 3581], 'recover': [2718], 'before': [2722], 'use.': [2723], 'Control': [2724], 'washed': [2729, 2815, 2854, 2893, 2912, 2967], 'ice-cold': [2731], 'sheets': [2736, 2813, 2835, 2852, 2890], 'Robinson': [2742], 'et': [2743, 2943, 3318], 'al.': [2744, 2944, 3319], '(32Robinson': [2745], 'L.J.': [2746, 2948], '263:': [2753], 'E383-E393PubMed': [2754], 'Cells': [2757], 'treated': [2759], '0.55': [2761], 'mg/ml': [2762], 'poly-l-lysine': [2763], 'followed': [2764, 2867, 3097, 3281, 3302], 'three': [2766, 2816, 2894, 2913, 3356], 'washes': [2767], 'hypotonic': [2769, 2793], 'buffer': [2770, 2791, 2794, 2820, 2972, 3096, 3141, 3198], '(23': [2771], 'KCl,': [2773], '10': [2774, 2990, 2993, 3012, 3213, 3228, 3238, 3254], 'HEPES,': [2776, 2975], 'pH': [2777, 2976, 3202], '7.5,': [2778], '1.7': [2779], 'MgCl2,': [2781], 'EGTA).': [2784], 'sonication': [2790, 2819], '(3×': [2792], 'μm': [2797], 'phenylmethylsulfonyl': [2798, 2988, 3226], 'fluoride': [2799], 'mmdithiothreitol)': [2802], 'sonicated': [2804], 'Fisher': [2807], 'probe': [2808], 'disrupter.': [2810], 'Plasma': [2811, 2888], 'times': [2817, 2895, 2914], 'fixed': [2822, 2832], '2%': [2824], 'paraformaldehyde': [2825], '20': [2827, 3023, 3046, 3132], 'min': [2828, 2840, 2863, 3024, 3047, 3062, 3239, 3255], 'ice.': [2830], 'quenched': [2837], '15': [2839, 2883], 'glycine.': [2847], 'blocked': [2856], '45': [2862], '°C,': [2866, 3280, 3574], '(1:100': [2873], 'dilution': [2874], 'antisera)': [2876], '(1:50': [2880], 'dilution)': [2881], 'lissamine': [2900], 'secondary': [2904], 'dark,': [2911], 'overlaid': [2917], 'drop': [2920], 'Vectashield,': [2922], 'visualized': [2924], 'confocal': [2926], 'fluorescence': [2927], 'microscopy.': [2928], 'Adipocyte': [2929], 'subcellular': [2930, 3809], 'fractions': [2932, 3136, 3810, 3856, 3998, 4021], 'differential': [2937, 3805], 'centrifugation': [2938, 3036, 3093, 3107, 3806], 'method': [2939], '(33Piper': [2945], 'Hess': [2947], '1991;': [2954], '260:': [2955], 'C570-C580Crossref': [2956], 'control': [2961, 3428, 3494], 'resuspended': [2969, 3138], 'HES': [2971, 3095, 3140], '(20': [2973], '7.4,': [2977, 3203], 'EDTA,': [2980], '255': [2982], 'sucrose': [2984, 3104, 3123], 'fluoride,': [2989, 3212, 3227], 'pepstatin,': [2992, 3233], 'aprotinin,': [2995, 3230], '5': [2997, 3234, 4194], 'leupeptin).': [2999], 'lysates': [3001], 'shearing': [3005], '22-gauge': [3010], 'needle': [3011], 'times.': [3013], 'Lysates': [3014], 'centrifuged': [3017, 3055, 3126], '19,000': [3019, 3090], '×': [3020, 3043, 3058, 3091, 3110, 3129], 'g': [3021, 3044, 3059, 3092, 3111, 3130], 'low': [3029, 3847, 3884, 4014, 4062], 'speed': [3030, 3070, 3848, 3851, 3885, 3905, 3933, 4015, 4019, 4063, 4103], 'pellet': [3031, 3071, 3080, 3086, 3886, 3906, 3934, 4016, 4020, 4064, 4104], '(LSP)': [3032], 'supernatant': [3040], '41,000': [3042], 'Supernatant': [3051], 'removed': [3053, 3120], '180,000': [3057], '75': [3061], 'cytosol': [3073, 3863, 4003, 4191], '(supernatant)': [3074], 'fractions.': [3075, 4004], 'crude': [3077], 'resuspending': [3084], 'initial': [3089], 'layering': [3099], 'onto': [3100, 3579], '1.12': [3102], 'm': [3103], 'cushion': [3105, 3124], '100,000': [3109], '60': [3113], 'min.': [3114, 3133], 'layer': [3118], '40,000': [3128], 'All': [3134], 'pelleted': [3135], 'assayed': [3143], 'soluble': [3145, 3249], 'content': [3147], '(34Sedmark': [3148], 'J.J.': [3149], 'Grossberg': [3150], 'S.E.': [3151], 'Anal.': [3152], '1977;': [3154], '79:': [3155], '544-552Crossref': [3156], '(2498)': [3159], 'Fractions': [3162], 'subjected': [3164, 3296], 'electrophoresis': [3166, 3298], 'SDS-PAGE,': [3169, 3301], 'transferred': [3170], 'polyvinylidene': [3172, 3306], 'difluoride': [3173, 3307], 'membranes,': [3174], 'immunoblotted': [3176], 'indicated': [3179, 4320], 'individual': [3182, 4397], 'figure': [3183], 'legends.': [3184], 'Whole': [3185, 3259], 'detergent': [3187], 'extracts': [3188, 3679], 'solubilization': [3192], 'Nonidet': [3195, 3205], 'P-40': [3196], 'lysis': [3197], '(25': [3199], 'Tris,': [3201], '1%': [3204], 'P-40,': [3206], 'glycerol,': [3208], 'sodium': [3211, 3215, 3219], 'pyrophosphate,': [3216], '137': [3217], 'chloride,': [3220], 'mmsodium': [3222], 'vanadate,': [3223], 'leupeptin)': [3236], 'Insoluble': [3243], 'material': [3244], 'separated': [3246], 'extract': [3250], 'microcentrifugation': [3252], 'lysate': [3261], '(2–4': [3262], 'mg)': [3263], 'combined': [3265], '4.5': [3267], 'affinity-purified': [3270], '2': [3276, 3290, 3570, 4328, 4418], 'A-Sepharose': [3288], 'h.': [3291], 'resultant': [3293], 'immunoprecipitates': [3294], 'transfer': [3304], 'immunoblotting.': [3309], 'LexA': [3311, 3383, 3431, 3497, 4389], 'two-hybrid': [3312, 3350, 3706], 'system,': [3313], 'originally': [3314], 'Gyuris': [3317], '(35Gyuris': [3320], 'Golemis': [3322], 'Chertkov': [3324], 'Brent': [3326], '75:': [3330], '791-803Abstract': [3331], '(1322)': [3337], 'Scholar),': [3339], 'here': [3342], 'examine': [3344, 3784], 'between': [3346], 'known': [3347], 'proteins.': [3348, 4399], 'system': [3351], 'employs': [3352], 'use': [3354], 'vectors:': [3357], '"bait,"': [3360], '"prey,"': [3363], 'p8op-lacZ': [3366, 3420, 3442, 3464], 'reporter': [3367, 3419, 3424, 3465, 3479, 3529], 'plasmid.': [3368], 'bait': [3370, 3459, 3475, 3500, 3527], 'fusions': [3376, 3396], 'fused': [3384], 'upstream': [3385], 'interest.': [3391], 'prey': [3393, 3538, 3562, 3703, 3707, 3768], 'generates': [3395], 'cassette': [3399], 'consisting': [3400], 'SV40': [3403], 'sequence,': [3406], '88-residue': [3408], 'B42': [3409], 'acidic': [3410], 'activator': [3411], 'domain,': [3412], 'hemagglutinin': [3415, 3697], 'tag.': [3417], 'carries': [3421, 3564], 'lacZ': [3423, 3634, 3659], 'gene': [3425, 3490], 'under': [3426, 3492], 'eight': [3430], 'operators': [3432], 'TATA': [3436], 'GAL1': [3440], 'promoter.': [3441], 'exhibits': [3443], 'transcriptional': [3445, 3504], 'activity': [3446], 'absence': [3449, 3508], 'LexA-fused': [3452], 'activator.': [3453], 'Syntaxin': [3454, 4400], 'co-transformed': [3461], 'pEGY48': [3469], 'strain': [3470], 'cells.': [3473], 'carry': [3481], 'HIS3': [3482], 'URA3': [3484], 'transformation': [3485, 3567], 'markers,': [3486], 'LEU2reporter': [3489], 'absolute': [3493], 'operators.': [3498, 3522], 'showed': [3501], 'intrinsic': [3503], 'activation': [3505, 4406], 'prey,': [3510], 'shown': [3513], 'enter': [3515], 'nucleus': [3518], 'transformants': [3524], 'carrying': [3525], 'competent': [3533], 'transformed': [3535], 'various': [3537], 'constructs': [3539], 'indicated,': [3541], 'plated': [3543, 3578], 'nitrogen': [3550], 'source,': [3551], 'amino': [3554], 'minus': [3556], 'uracil,': [3557], 'histidine,': [3558], 'tryptophan': [3560], '(the': [3561], 'TRP1': [3566], 'marker).': [3568], '30': [3573], 'replica': [3577], 'X-gal:': [3583], 'Ura-His-Trp-,': [3585, 3589, 3603], 'Ura-His-Trp-Leu-,': [3587, 3608], 'gal/raf': [3588, 3591, 3615], 'Ura-His-Trp-Leu-': [3592], 'scored': [3594, 3640, 3652, 3756], 'interaction.': [3596], 'Plates': [3597], 'showing': [3598], 'white': [3599], 'colonies': [3600, 3612], 'growth': [3605], 'blue': [3611, 3637, 3649, 3730, 3748, 3781], 'given': [3618], 'score': [3620], '++++': [3622], 'indication': [3625], 'level': [3628], 'interaction': [3630, 4237, 4364, 4384, 4426], 'measured': [3632], 'expression.': [3635], 'No': [3636], 'color': [3638, 3650, 3731, 3749], '−,': [3642, 3761], 'while': [3643], '25,': [3644], '75%': [3647], 'dark': [3648], '+,': [3654], '++,': [3655, 3759], '+++,': [3657], 'determined': [3662, 3725], 'liquid': [3664], 'assay': [3665, 3676, 4376], 'o-nitrophenyl-β-d-galactopyranoside': [3667], 'substrate': [3669], 'our': [3673], 'whole': [3674, 3827], 'plate': [3675], 'scoring.': [3677], 'Liquid': [3678], 'analyzed': [3681], 'immunoblotting': [3689], 'directly': [3693, 4223], 'imbedded': [3700], 'Munc18c-AD': [3720, 3740], 'protein.': [3722], 'Competition': [3723], 'compared': [3732, 4029], 'present.': [3746], 'Dark': [3747], '100,': [3751], '75,': [3752], '50%': [3754, 3778], '++++,': [3758], 'respectively,': [3762], 'equal': [3764], 'theoretically': [3773], 'maximal': [3777], 'color.': [3782], 'To': [3783, 4360], 'comparison': [3791], 'SNARE': [3796, 4398], 'translocation,': [3802], 'isolate': [3808], '(Fig.': [3814, 3836, 3865, 3888, 3922, 4022, 4035, 4112, 4192, 4212, 4417], '1).': [3815], 'Immunoblot': [3816], 'demonstrated': [3818], 'presence': [3820], 'extract,': [3829], 'unaffected': [3832], 'treatment': [3835], '1,lanes': [3837, 4113, 4193], '2).': [3840], 'detected': [3844], 'pellet,': [3849, 3852], 'completely': [3859], 'absent': [3860, 4001], 'fraction': [3864, 3887, 3907, 3921, 3935, 4034, 4065, 4109], '1,': [3866, 3889, 3923, 4023, 4036, 4213], 'lanes': [3867, 3890, 3924, 4024, 4037, 4214], '3–10).': [3868], 'and4),': [3892], 'amount': [3913, 4184], '7–10).': [3925, 4114, 4215], 'decrease': [3927], 'concomitant': [3936], 'recruitment': [3939], 'characteristic': [3945], '(2Czech': [3950], '5Rea': [3963], 'Scholar,36Kandror': [3973], 'Similar': [3986], 'GLUT4,': [3988], 'particulate': [3997], 'Interestingly,': [4005], 'relative': [4007, 4383], 'proportion': [4008], '3,4,': [4025], '7,': [4026], '8)': [4028], '9': [4038], 'and10)': [4039], 'significantly': [4041], 'greater': [4042], 'than': [4043, 4110], 'VAMP2.': [4046], 'being': [4052, 4121], 'more': [4053, 4095], 'endosomes,': [4056], 'enriched': [4059], '(37Martin': [4066], 'Tellam': [4068], 'Livingstone': [4070], 'C.': [4071], '134:': [4082], '625-635Crossref': [4083], '(180)': [4086], 'marked': [4096], 'population': [4129], 'distinct': [4130], 'endosome': [4134], 'pool': [4135], 'vesicular': [4166], 'fraction,': [4179], 'although': [4180], 'relatively': [4182], 'small': [4183], '6).': [4196], 'redistribution': [4202], 'following': [4209], 'Since': [4216], 'does': [4218], 'contain': [4220], 'responsible': [4224], 'targeting,': [4227], 'probably': [4234], 'reflects': [4235], 'other': [4239], 'membrane-bound': [4241], 'including': [4243], '38Okamoto': [4268], '31459-31464Abstract': [4277], '(277)': [4285], '39Verhage': [4288], 'Vries': [4291], 'K.J.': [4292], 'Roshol': [4293], 'Burbach': [4295], 'J.P.H.': [4296], 'Gispen': [4297], 'W.H.': [4298], '18:': [4303], '453-461Abstract': [4304], '(142)': [4312], 'vitro': [4316], 'assays': [4318], 'can': [4323], 'selectively': [4324], '(28Tellam': [4332], 'further': [4361], 'investigate': [4362], 'two-': [4373], 'systems': [4377], '(Fig.2).': [4378], 'Initially,': [4379], 'examined': [4381], '(bait)': [4394], 'interacted': [4403], '(prey)': [4409], 'A).': [4419], 'Similarly,': [4420], 'displayed': [4422], 'positive': [4425], '4,': [4429], 'whereas': [4430], 'detec': [4434]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2104389135', 'counts_by_year': [{'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 7}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 11}, {'year': 2012, 'cited_by_count': 8}], 'updated_date': '2024-12-24T14:17:25.450159', 'created_date': '2016-06-24'}