Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2103551282', 'doi': 'https://doi.org/10.3109/0284186x.2010.510640', 'title': 'Dose- and LET-painting with particle therapy', 'display_name': 'Dose- and LET-painting with particle therapy', 'publication_year': 2010, 'publication_date': '2010-09-13', 'ids': {'openalex': 'https://openalex.org/W2103551282', 'doi': 'https://doi.org/10.3109/0284186x.2010.510640', 'mag': '2103551282', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20831510'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/0284186x.2010.510640', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1043257', 'display_name': 'Acta Oncologica', 'issn_l': '0284-186X', 'issn': ['0284-186X', '1651-226X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040106184', 'display_name': 'Niels Bassler', 'orcid': 'https://orcid.org/0000-0002-4160-1078'}, 'institutions': [{'id': 'https://openalex.org/I204337017', 'display_name': 'Aarhus University', 'ror': 'https://ror.org/01aj84f44', 'country_code': 'DK', 'type': 'education', 'lineage': ['https://openalex.org/I204337017']}, {'id': 'https://openalex.org/I2802335433', 'display_name': 'Aarhus University Hospital', 'ror': 'https://ror.org/040r8fr65', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802335433']}], 'countries': ['DK'], 'is_corresponding': True, 'raw_author_name': 'Niels Bassler', 'raw_affiliation_strings': ['Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark', 'Department of Physics and Astronomy, University of Aarhus, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Department of Physics and Astronomy, University of Aarhus, Denmark', 'institution_ids': ['https://openalex.org/I204337017']}, {'raw_affiliation_string': 'Department of Experimental Clinical Oncology, Aarhus University Hospital, Denmark', 'institution_ids': ['https://openalex.org/I2802335433']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060753820', 'display_name': 'Oliver Jäkel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210151100', 'display_name': 'DKFZ-ZMBH Alliance', 'ror': 'https://ror.org/05x8b4491', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529', 'https://openalex.org/I223822909', 'https://openalex.org/I4210151100']}, {'id': 'https://openalex.org/I17937529', 'display_name': 'German Cancer Research Center', 'ror': 'https://ror.org/04cdgtt98', 'country_code': 'DE', 'type': 'facility', 'lineage': ['https://openalex.org/I1305996414', 'https://openalex.org/I17937529']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Oliver Jäkel', 'raw_affiliation_strings': ['Deutsches Krebsforschungszentrum, Heidelberg, Germany'], 'affiliations': [{'raw_affiliation_string': 'Deutsches Krebsforschungszentrum, Heidelberg, Germany', 'institution_ids': ['https://openalex.org/I4210151100', 'https://openalex.org/I17937529']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5072835716', 'display_name': 'C. Søndergaard', 'orcid': 'https://orcid.org/0000-0002-3607-7814'}, 'institutions': [{'id': 'https://openalex.org/I2802335433', 'display_name': 'Aarhus University Hospital', 'ror': 'https://ror.org/040r8fr65', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802335433']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Christian Skou Søndergaard', 'raw_affiliation_strings': ['Department of Medical Physics, Aarhus University Hospital, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Physics, Aarhus University Hospital, Denmark', 'institution_ids': ['https://openalex.org/I2802335433']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5010592666', 'display_name': 'J. Petersen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802335433', 'display_name': 'Aarhus University Hospital', 'ror': 'https://ror.org/040r8fr65', 'country_code': 'DK', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802335433']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'Jørgen B. Petersen', 'raw_affiliation_strings': ['Department of Medical Physics, Aarhus University Hospital, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Department of Medical Physics, Aarhus University Hospital, Denmark', 'institution_ids': ['https://openalex.org/I2802335433']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5040106184'], 'corresponding_institution_ids': ['https://openalex.org/I204337017', 'https://openalex.org/I2802335433'], 'apc_list': None, 'apc_paid': None, 'fwci': 5.416, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 136, 'citation_normalized_percentile': {'value': 0.953316, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '49', 'issue': '7', 'first_page': '1170', 'last_page': '1176'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11176', 'display_name': 'Radiation Therapy and Dosimetry', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11176', 'display_name': 'Radiation Therapy and Dosimetry', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10358', 'display_name': 'Advanced Radiotherapy Techniques', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/3108', 'display_name': 'Radiation'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11216', 'display_name': 'Radiation Detection and Scintillator Technologies', 'score': 0.9816, 'subfield': {'id': 'https://openalex.org/subfields/3108', 'display_name': 'Radiation'}, 'field': {'id': 'https://openalex.org/fields/31', 'display_name': 'Physics and Astronomy'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/sobp', 'display_name': 'Sobp', 'score': 0.9260166}, {'id': 'https://openalex.org/keywords/particle-therapy', 'display_name': 'Particle Therapy', 'score': 0.6654774}, {'id': 'https://openalex.org/keywords/oxygen-enhancement-ratio', 'display_name': 'Oxygen enhancement ratio', 'score': 0.57528186}, {'id': 'https://openalex.org/keywords/linear-energy-transfer', 'display_name': 'Linear energy transfer', 'score': 0.51611865}, {'id': 'https://openalex.org/keywords/limiting', 'display_name': 'Limiting', 'score': 0.41831097}], 'concepts': [{'id': 'https://openalex.org/C2781298738', 'wikidata': 'https://www.wikidata.org/wiki/Q18041535', 'display_name': 'Sobp', 'level': 4, 'score': 0.9260166}, {'id': 'https://openalex.org/C2780944729', 'wikidata': 'https://www.wikidata.org/wiki/Q897227', 'display_name': 'Bragg peak', 'level': 3, 'score': 0.75051844}, {'id': 'https://openalex.org/C2778418280', 'wikidata': 'https://www.wikidata.org/wiki/Q38276304', 'display_name': 'Particle therapy', 'level': 3, 'score': 0.6654774}, {'id': 'https://openalex.org/C509974204', 'wikidata': 'https://www.wikidata.org/wiki/Q180507', 'display_name': 'Radiation therapy', 'level': 2, 'score': 0.60895586}, {'id': 'https://openalex.org/C163372243', 'wikidata': 'https://www.wikidata.org/wiki/Q1981506', 'display_name': 'Oxygen enhancement ratio', 'level': 3, 'score': 0.57528186}, {'id': 'https://openalex.org/C2989005', 'wikidata': 'https://www.wikidata.org/wiki/Q214963', 'display_name': 'Nuclear medicine', 'level': 1, 'score': 0.5666212}, {'id': 'https://openalex.org/C145148216', 'wikidata': 'https://www.wikidata.org/wiki/Q36496', 'display_name': 'Ion', 'level': 2, 'score': 0.5185545}, {'id': 'https://openalex.org/C86611320', 'wikidata': 'https://www.wikidata.org/wiki/Q1699996', 'display_name': 'Linear energy transfer', 'level': 3, 'score': 0.51611865}, {'id': 'https://openalex.org/C201645570', 'wikidata': 'https://www.wikidata.org/wiki/Q830637', 'display_name': 'Radiation treatment planning', 'level': 3, 'score': 0.5154141}, {'id': 'https://openalex.org/C153385146', 'wikidata': 'https://www.wikidata.org/wiki/Q18335', 'display_name': 'Radiation', 'level': 2, 'score': 0.49464318}, {'id': 'https://openalex.org/C159317903', 'wikidata': 'https://www.wikidata.org/wiki/Q3198', 'display_name': 'Photon', 'level': 2, 'score': 0.42234316}, {'id': 'https://openalex.org/C188198153', 'wikidata': 'https://www.wikidata.org/wiki/Q1613840', 'display_name': 'Limiting', 'level': 2, 'score': 0.41831097}, {'id': 'https://openalex.org/C168834538', 'wikidata': 'https://www.wikidata.org/wiki/Q3705329', 'display_name': 'Beam (structure)', 'level': 2, 'score': 0.39483792}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.3883847}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3709132}, {'id': 'https://openalex.org/C111337013', 'wikidata': 'https://www.wikidata.org/wiki/Q2737837', 'display_name': 'Irradiation', 'level': 2, 'score': 0.31378683}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.28854072}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.15697232}, {'id': 'https://openalex.org/C185544564', 'wikidata': 'https://www.wikidata.org/wiki/Q81197', 'display_name': 'Nuclear physics', 'level': 1, 'score': 0.14171702}, {'id': 'https://openalex.org/C78519656', 'wikidata': 'https://www.wikidata.org/wiki/Q101333', 'display_name': 'Mechanical engineering', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D018499', 'descriptor_name': 'Linear Energy Transfer', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000000981', 'qualifier_name': 'diagnostic imaging', 'is_major_topic': True}, {'descriptor_ui': 'D018787', 'descriptor_name': 'Radiation Oncology', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002244', 'descriptor_name': 'Carbon', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D003198', 'descriptor_name': 'Computer Simulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019583', 'descriptor_name': 'Dose Fractionation, Radiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004307', 'descriptor_name': 'Dose-Response Relationship, Radiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018499', 'descriptor_name': 'Linear Energy Transfer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000532', 'qualifier_name': 'radiotherapy', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D019047', 'descriptor_name': 'Phantoms, Imaging', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018787', 'descriptor_name': 'Radiation Oncology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011857', 'descriptor_name': 'Radiographic Image Interpretation, Computer-Assisted', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D011857', 'descriptor_name': 'Radiographic Image Interpretation, Computer-Assisted', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011857', 'descriptor_name': 'Radiographic Image Interpretation, Computer-Assisted', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': False}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011880', 'descriptor_name': 'Radiotherapy Planning, Computer-Assisted', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': False}, {'descriptor_ui': 'D050397', 'descriptor_name': 'Radiotherapy, Intensity-Modulated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050397', 'descriptor_name': 'Radiotherapy, Intensity-Modulated', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/0284186x.2010.510640', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S1043257', 'display_name': 'Acta Oncologica', 'issn_l': '0284-186X', 'issn': ['0284-186X', '1651-226X'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20831510', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'score': 0.52, 'id': 'https://metadata.un.org/sdg/6'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W1847687345', 'https://openalex.org/W1967664788', 'https://openalex.org/W1977034238', 'https://openalex.org/W1979944875', 'https://openalex.org/W1991311137', 'https://openalex.org/W1991938051', 'https://openalex.org/W1999494285', 'https://openalex.org/W2004085462', 'https://openalex.org/W2006238704', 'https://openalex.org/W2009606038', 'https://openalex.org/W2013716121', 'https://openalex.org/W2016223985', 'https://openalex.org/W2036789410', 'https://openalex.org/W2039665830', 'https://openalex.org/W2041753214', 'https://openalex.org/W2042499995', 'https://openalex.org/W2042756123', 'https://openalex.org/W2055646653', 'https://openalex.org/W2056399692', 'https://openalex.org/W2060936143', 'https://openalex.org/W2076771282', 'https://openalex.org/W2091894720', 'https://openalex.org/W2123838717', 'https://openalex.org/W2124975411', 'https://openalex.org/W2130443041', 'https://openalex.org/W2147650207', 'https://openalex.org/W2161674690', 'https://openalex.org/W2162112099', 'https://openalex.org/W4240091254'], 'related_works': ['https://openalex.org/W3086162142', 'https://openalex.org/W2903840723', 'https://openalex.org/W2886323557', 'https://openalex.org/W2170033793', 'https://openalex.org/W2122776005', 'https://openalex.org/W2103551282', 'https://openalex.org/W2088005887', 'https://openalex.org/W2065672920', 'https://openalex.org/W2057788248', 'https://openalex.org/W1975210359'], 'abstract_inverted_index': {'Tumour': [0], 'hypoxia': [1, 102], 'is': [2, 28, 46], 'one': [3], 'of': [4, 17, 20, 34, 50, 63, 124, 194, 221, 227, 250], 'the': [5, 31, 35, 64, 68, 74, 78, 91, 122, 125, 147, 187, 191, 195, 201, 218, 222, 228, 235], 'limiting': [6], 'factors': [7], 'in': [8, 12, 30, 60, 67, 85, 90, 116, 158, 224], 'obtaining': [9], 'tumour': [10, 273], 'control': [11, 274, 279], 'radiotherapy.': [13], 'The': [14, 110], 'high-LET': [15, 111, 219], 'region': [16, 112], 'a': [18, 47, 61, 97, 152, 268], 'beam': [19], 'heavy': [21], 'charged': [22], 'particles': [23], 'such': [24, 162, 172], 'as': [25, 163], 'carbon': [26, 136, 165], 'ions': [27, 166], 'located': [29], 'distal': [32], 'part': [33, 220], 'Bragg': [36, 43, 52], 'peak.': [37], 'A': [38], 'modulated': [39], 'or': [40, 107, 128], 'spread': [41], 'out': [42], 'peak': [44], '(SOBP)': [45], 'weighted': [48], 'function': [49], 'several': [51], 'peaks': [53], 'at': [54, 182], 'various': [55], 'energies,': [56], 'which': [57], 'however': [58], 'results': [59], 'dilution': [62], 'dose-average': [65], 'LET': [66, 79, 89, 142, 153, 199, 255, 265], 'target': [69, 92, 188], 'volume.': [70, 93, 189], 'Here,': [71], 'we': [72, 206], 'investigate': [73], 'possibility': [75], 'to': [76, 87, 99, 234, 270], 'redistribute': [77], 'by': [80, 216, 247], 'dedicated': [81], 'treatment': [82, 160, 258], 'plan': [83], 'optimisation,': [84], 'order': [86], 'maximise': [88], 'This': [94], 'may': [95, 244], 'be': [96, 114, 156, 180, 214, 245], 'strategy': [98], 'potentially': [100], 'overcome': [101], 'along': [103], 'with': [104, 167], 'dose': [105, 108, 127, 263], 'escalation': [106], 'painting.': [109], 'can': [113, 155, 179, 213], 'shaped': [115], 'very': [117, 140], 'different': [118, 141], 'ways,': [119], 'while': [120], 'maintaining': [121], 'distribution': [123], 'absorbed': [126], 'biological': [129], 'effective': [130], 'dose.': [131], 'Treatment': [132], 'plans': [133], 'involving': [134], 'only': [135], 'ion': [137], 'beams,': [138], 'show': [139], 'distributions': [143], 'depending': [144], 'on': [145, 261], 'how': [146], 'fields': [148], 'are': [149], 'arranged.': [150], 'Alternatively,': [151], 'boost': [154], 'applied': [157], 'multi-modal': [159], 'planning,': [161], 'combining': [164], 'protons': [168], 'and/or': [169, 275], 'photons.': [170], 'For': [171], 'mixed': [173], 'radiation': [174, 223, 233], 'modalities,': [175], 'significant': [176], '"LET': [177], 'boosts"': [178], 'achieved': [181, 215, 246], 'nearly': [183], 'arbitrary': [184], 'positions': [185], 'within': [186], 'Following': [190], 'general': [192], 'understanding': [193], 'relationship': [196], 'between': [197], 'hypoxia,': [198], 'and': [200, 230, 264], 'oxygen': [202], 'enhancement': [203], 'ratio': [204], '(OER),': [205], 'conclude,': [207], 'that': [208, 241], 'an': [209], 'additional': [210, 242], 'therapeutic': [211], 'advantage': [212], 'confining': [217], 'hypoxic': [225], 'compartments': [226], 'tumour,': [229], 'applying': [231], 'low-LET': [232], 'normoxic': [236], 'tissue.': [237], 'We': [238], 'also': [239], 'anticipate': [240], 'advantages': [243], 'deliberate': [248], 'sparing': [249], 'normal': [251, 277], 'tissue': [252, 278], 'from': [253], 'high': [254], 'regions.': [256], 'Consequently,': [257], 'planning': [259], 'based': [260], 'simultaneous': [262], 'optimisation': [266], 'has': [267], 'potential': [269], 'achieve': [271], 'higher': [272], 'reduced': [276], 'probability': [280], '(NTCP).': [281]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2103551282', 'counts_by_year': [{'year': 2024, 'cited_by_count': 12}, {'year': 2023, 'cited_by_count': 14}, {'year': 2022, 'cited_by_count': 10}, {'year': 2021, 'cited_by_count': 10}, {'year': 2020, 'cited_by_count': 12}, {'year': 2019, 'cited_by_count': 7}, {'year': 2018, 'cited_by_count': 10}, {'year': 2017, 'cited_by_count': 13}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 10}, {'year': 2014, 'cited_by_count': 9}, {'year': 2013, 'cited_by_count': 10}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-25T09:18:55.328039', 'created_date': '2016-06-24'}