Publication Information

{'id': 'https://openalex.org/W2101387120', 'doi': 'https://doi.org/10.1084/jem.20040774', 'title': 'Chemokine Receptor Expression Identifies Pre–T Helper (Th)1, Pre–Th2, and Nonpolarized Cells among Human CD4+ Central Memory T Cells', 'display_name': 'Chemokine Receptor Expression Identifies Pre–T Helper (Th)1, Pre–Th2, and Nonpolarized Cells among Human CD4+ Central Memory T Cells', 'publication_year': 2004, 'publication_date': '2004-09-20', 'ids': {'openalex': 'https://openalex.org/W2101387120', 'doi': 'https://doi.org/10.1084/jem.20040774', 'mag': '2101387120', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15381728', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2211963'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.20040774', 'pdf_url': 'https://rupress.org/jem/article-pdf/200/6/725/1151468/jem2006725.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://rupress.org/jem/article-pdf/200/6/725/1151468/jem2006725.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5027896174', 'display_name': 'Laura Rivino', 'orcid': 'https://orcid.org/0000-0001-6213-9794'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Laura Rivino', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029819437', 'display_name': 'Mara Messi', 'orcid': None}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Mara Messi', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006902186', 'display_name': 'David Jarrossay', 'orcid': 'https://orcid.org/0000-0002-0924-6395'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'David Jarrossay', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059965999', 'display_name': 'Antonio Lanzavecchia', 'orcid': 'https://orcid.org/0000-0002-3041-7240'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Antonio Lanzavecchia', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5047171254', 'display_name': 'Federica Sallusto', 'orcid': 'https://orcid.org/0000-0003-3750-2752'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Federica Sallusto', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5020503463', 'display_name': 'Jens Geginat', 'orcid': 'https://orcid.org/0000-0003-4813-0384'}, 'institutions': [], 'countries': ['CH'], 'is_corresponding': False, 'raw_author_name': 'Jens Geginat', 'raw_affiliation_strings': ['Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland'], 'affiliations': [{'raw_affiliation_string': 'Institute for Research in Biomedicine, 6500 Bellinzona, Switzerland', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 6.453, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 289, 'citation_normalized_percentile': {'value': 0.999889, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '200', 'issue': '6', 'first_page': '725', 'last_page': '735'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10580', 'display_name': 'Immunotherapy and Immune Responses', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/zap70', 'display_name': 'ZAP70', 'score': 0.60713077}, {'id': 'https://openalex.org/keywords/interleukin-3', 'display_name': 'Interleukin 3', 'score': 0.58301115}, {'id': 'https://openalex.org/keywords/cxcr5', 'display_name': 'CXCR5', 'score': 0.44973862}], 'concepts': [{'id': 'https://openalex.org/C129374314', 'wikidata': 'https://www.wikidata.org/wiki/Q909381', 'display_name': 'Interleukin 21', 'level': 4, 'score': 0.716579}, {'id': 'https://openalex.org/C79484868', 'wikidata': 'https://www.wikidata.org/wiki/Q5971673', 'display_name': 'IL-2 receptor', 'level': 4, 'score': 0.63262135}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.60727906}, {'id': 'https://openalex.org/C120642132', 'wikidata': 'https://www.wikidata.org/wiki/Q14907110', 'display_name': 'ZAP70', 'level': 5, 'score': 0.60713077}, {'id': 'https://openalex.org/C67662055', 'wikidata': 'https://www.wikidata.org/wiki/Q1047791', 'display_name': 'Antigen-presenting cell', 'level': 4, 'score': 0.59693736}, {'id': 'https://openalex.org/C131665280', 'wikidata': 'https://www.wikidata.org/wiki/Q14866169', 'display_name': 'Interleukin 3', 'level': 5, 'score': 0.58301115}, {'id': 'https://openalex.org/C148125776', 'wikidata': 'https://www.wikidata.org/wiki/Q1622348', 'display_name': 'CD28', 'level': 4, 'score': 0.56110513}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.5562572}, {'id': 'https://openalex.org/C39347974', 'wikidata': 'https://www.wikidata.org/wiki/Q21135811', 'display_name': 'CD40', 'level': 4, 'score': 0.5293646}, {'id': 'https://openalex.org/C139563560', 'wikidata': 'https://www.wikidata.org/wiki/Q224930', 'display_name': 'Natural killer T cell', 'level': 4, 'score': 0.5198108}, {'id': 'https://openalex.org/C149532602', 'wikidata': 'https://www.wikidata.org/wiki/Q2409681', 'display_name': 'Interleukin 12', 'level': 4, 'score': 0.4822486}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.46959296}, {'id': 'https://openalex.org/C2776708503', 'wikidata': 'https://www.wikidata.org/wiki/Q1024612', 'display_name': 'CXCR5', 'level': 5, 'score': 0.44973862}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.44036043}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.35969663}, {'id': 'https://openalex.org/C12823836', 'wikidata': 'https://www.wikidata.org/wiki/Q24720618', 'display_name': 'Chemokine receptor', 'level': 4, 'score': 0.26737475}, {'id': 'https://openalex.org/C13373296', 'wikidata': 'https://www.wikidata.org/wiki/Q421866', 'display_name': 'Chemokine', 'level': 3, 'score': 0.20147836}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.18115196}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.08061513}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006412', 'descriptor_name': 'Hematopoietic Stem Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D007156', 'descriptor_name': 'Immunologic Memory', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D019707', 'descriptor_name': 'Receptors, Chemokine', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D018121', 'descriptor_name': 'Receptors, Cytokine', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': True}, {'descriptor_ui': 'D018417', 'descriptor_name': 'Th1 Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D018418', 'descriptor_name': 'Th2 Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016764', 'descriptor_name': 'Cell Polarity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006412', 'descriptor_name': 'Hematopoietic Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006412', 'descriptor_name': 'Hematopoietic Stem Cells', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015847', 'descriptor_name': 'Interleukin-4', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054398', 'descriptor_name': 'Receptors, CCR4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054367', 'descriptor_name': 'Receptors, CXCR3', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D054380', 'descriptor_name': 'Receptors, CXCR5', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019707', 'descriptor_name': 'Receptors, Chemokine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018121', 'descriptor_name': 'Receptors, Cytokine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018417', 'descriptor_name': 'Th1 Cells', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D018417', 'descriptor_name': 'Th1 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018418', 'descriptor_name': 'Th2 Cells', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D018418', 'descriptor_name': 'Th2 Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.20040774', 'pdf_url': 'https://rupress.org/jem/article-pdf/200/6/725/1151468/jem2006725.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2211963', 'pdf_url': 'https://europepmc.org/articles/pmc2211963?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by-nc-sa', 'license_id': 'https://openalex.org/licenses/cc-by-nc-sa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211963', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/2434/730436', 'pdf_url': 'https://air.unimi.it/bitstream/2434/730436/2/jem2006725.pdf', 'source': {'id': 'https://openalex.org/S4306400516', 'display_name': 'Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I189158943', 'host_organization_name': 'University of Milan', 'host_organization_lineage': ['https://openalex.org/I189158943'], 'host_organization_lineage_names': ['University of Milan'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15381728', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1084/jem.20040774', 'pdf_url': 'https://rupress.org/jem/article-pdf/200/6/725/1151468/jem2006725.pdf', 'source': {'id': 'https://openalex.org/S22947807', 'display_name': 'The Journal of Experimental Medicine', 'issn_l': '0022-1007', 'issn': ['0022-1007', '1540-9538'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315676', 'host_organization_name': 'Rockefeller University Press', 'host_organization_lineage': ['https://openalex.org/P4310315676'], 'host_organization_lineage_names': ['Rockefeller University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.67}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 59, 'referenced_works': ['https://openalex.org/W1519517175', 'https://openalex.org/W1534336889', 'https://openalex.org/W1580217007', 'https://openalex.org/W1584448102', 'https://openalex.org/W1601504908', 'https://openalex.org/W1602835962', 'https://openalex.org/W1603529984', 'https://openalex.org/W1610017743', 'https://openalex.org/W1661544713', 'https://openalex.org/W1729103553', 'https://openalex.org/W1840718005', 'https://openalex.org/W1906491439', 'https://openalex.org/W1945834141', 'https://openalex.org/W1967994686', 'https://openalex.org/W1970318694', 'https://openalex.org/W1977189837', 'https://openalex.org/W1981027928', 'https://openalex.org/W1981480494', 'https://openalex.org/W1988181926', 'https://openalex.org/W1991082879', 'https://openalex.org/W1994340919', 'https://openalex.org/W1995835059', 'https://openalex.org/W1999168221', 'https://openalex.org/W2001433846', 'https://openalex.org/W2006027051', 'https://openalex.org/W2010234200', 'https://openalex.org/W2012221707', 'https://openalex.org/W2025484368', 'https://openalex.org/W2027609828', 'https://openalex.org/W2029128444', 'https://openalex.org/W2030000864', 'https://openalex.org/W2038417994', 'https://openalex.org/W2053513948', 'https://openalex.org/W2063001043', 'https://openalex.org/W2077325919', 'https://openalex.org/W2077884399', 'https://openalex.org/W2078535398', 'https://openalex.org/W2081596482', 'https://openalex.org/W2082871926', 'https://openalex.org/W2091301099', 'https://openalex.org/W2107225522', 'https://openalex.org/W2113847305', 'https://openalex.org/W2116738479', 'https://openalex.org/W2117342688', 'https://openalex.org/W2124190967', 'https://openalex.org/W2126302947', 'https://openalex.org/W2133997960', 'https://openalex.org/W2136084693', 'https://openalex.org/W2141088882', 'https://openalex.org/W2144690750', 'https://openalex.org/W2151962109', 'https://openalex.org/W2160129587', 'https://openalex.org/W2165505341', 'https://openalex.org/W2171377431', 'https://openalex.org/W2171831396', 'https://openalex.org/W2172466148', 'https://openalex.org/W2270208951', 'https://openalex.org/W4249383241', 'https://openalex.org/W4313331406'], 'related_works': ['https://openalex.org/W947332346', 'https://openalex.org/W4313373310', 'https://openalex.org/W4313349742', 'https://openalex.org/W3037856584', 'https://openalex.org/W2605394274', 'https://openalex.org/W2146087639', 'https://openalex.org/W2117897995', 'https://openalex.org/W2071127998', 'https://openalex.org/W2037351868', 'https://openalex.org/W1988786742'], 'abstract_inverted_index': {'We': [0, 183], 'previously': [1], 'reported': [2], 'that': [3, 54, 112, 185], 'central–memory': [4], 'T': [5, 29, 35, 44, 147, 188, 210], 'cells': [6, 30, 69, 81, 100, 122, 161, 189, 194, 218], '(TCM': [7], 'cells),': [8], 'which': [9], 'express': [10], 'lymph': [11], 'node': [12], 'homing': [13], 'receptors': [14, 57], 'CCR7': [15, 131], 'and': [16, 93, 97, 107, 116, 125, 129, 132, 159, 171, 180, 195], 'CD62L,': [17], 'are': [18, 190], 'largely': [19, 175], 'devoid': [20], 'of': [21, 27, 75, 198, 208, 222], 'effector': [22], 'functions': [23], 'but': [24, 86], 'acquire': [25], 'characteristics': [26], 'effector–memory': [28], '(TEM': [31], 'cells)': [32, 40], '(i.e.,': [33], 'CCR7−': [34, 105], 'helper': [36], '[Th]1': [37], 'or': [38, 48], 'Th2': [39, 108], 'after': [41], 'stimulation': [42], 'with': [43], 'cell': [45, 66, 148, 211], 'receptor': [46, 149], 'agonists': [47], 'homeostatic': [49], 'cytokines.': [50], 'Here': [51], 'we': [52], 'show': [53], 'three': [55], 'chemokine': [56], 'identify': [58], 'functional': [59], 'subsets': [60, 143, 197], 'within': [61], 'the': [62, 206, 220], 'human': [63], 'CD4+': [64], 'TCM': [65, 68, 80, 96, 99, 121, 179, 199, 217], 'pool.': [67], 'expressing': [70], 'CXCR3': [71, 124], 'secreted': [72], 'low': [73, 146], 'amounts': [74], 'interferon': [76], 'γ,': [77], 'whereas': [78], 'CCR4+': [79, 98], 'produced': [82], 'some': [83], 'interleukin': [84], '(IL)-4,': [85], 'not': [87], 'IL-5.': [88], 'In': [89], 'response': [90], 'to': [91, 169, 177], 'IL-7': [92], 'IL-15,': [94], 'CXCR3+': [95, 178], 'invariably': [101], 'generated': [102], 'fully': [103], 'differentiated': [104], 'Th1': [106], 'cells,': [109, 140], 'respectively,': [110], 'suggesting': [111], 'they': [113], 'represent': [114], 'pre-Th1': [115], 'pre-Th2': [117], 'cells.': [118, 182, 200], 'Conversely,': [119, 166], 'CXCR5+': [120], 'lacking': [123], 'CCR4': [126], 'remained': [127], 'nonpolarized': [128], 'retained': [130], 'CD62L': [133], 'expression': [134], 'upon': [135], 'cytokine-driven': [136], 'expansion.': [137], 'Unlike': [138], 'naive': [139], 'all': [141], 'memory': [142, 187], 'had': [144], 'a': [145], 'rearrangement': [150], 'excision': [151], 'circle': [152], 'content,': [153], 'spontaneously': [154], 'incorporated': [155], 'bromodeoxyuridine': [156], 'ex': [157], 'vivo,': [158], 'contained': [160], 'specific': [162], 'for': [163], 'tetanus': [164], 'toxoid.': [165], 'recall': [167], 'responses': [168, 212], 'cytomegalovirus': [170], 'vaccinia': [172], 'virus': [173], 'were': [174], 'restricted': [176], 'TEM': [181, 193], 'conclude': [184], 'antigen-specific': [186], 'distributed': [191], 'between': [192], 'different': [196], 'Our': [201], 'results': [202], 'also': [203], 'explain': [204], 'how': [205], 'quality': [207], 'primary': [209], 'could': [213], 'be': [214], 'maintained': [215], 'by': [216], 'in': [219], 'absence': [221], 'antigen.': [223]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2101387120', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 15}, {'year': 2022, 'cited_by_count': 7}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 10}, {'year': 2019, 'cited_by_count': 9}, {'year': 2018, 'cited_by_count': 13}, {'year': 2017, 'cited_by_count': 20}, {'year': 2016, 'cited_by_count': 18}, {'year': 2015, 'cited_by_count': 12}, {'year': 2014, 'cited_by_count': 19}, {'year': 2013, 'cited_by_count': 24}, {'year': 2012, 'cited_by_count': 15}], 'updated_date': '2024-12-11T16:32:35.136515', 'created_date': '2016-06-24'}