Publication Information

{'id': 'https://openalex.org/W2101231917', 'doi': 'https://doi.org/10.1111/j.1750-3639.2010.00468.x', 'title': 'Monitoring of Tumor Growth and Post‐Irradiation Recurrence in a Diffuse Intrinsic Pontine Glioma Mouse Model', 'display_name': 'Monitoring of Tumor Growth and Post‐Irradiation Recurrence in a Diffuse Intrinsic Pontine Glioma Mouse Model', 'publication_year': 2010, 'publication_date': '2010-12-15', 'ids': {'openalex': 'https://openalex.org/W2101231917', 'doi': 'https://doi.org/10.1111/j.1750-3639.2010.00468.x', 'mag': '2101231917', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21159008', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/8094295'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1750-3639.2010.00468.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S9094144', 'display_name': 'Brain Pathology', 'issn_l': '1015-6305', 'issn': ['1015-6305', '1750-3639'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094295', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5053017424', 'display_name': 'Viola Caretti', 'orcid': 'https://orcid.org/0000-0002-6702-1426'}, 'institutions': [{'id': 'https://openalex.org/I911458345', 'display_name': 'Amsterdam UMC Location VUmc', 'ror': 'https://ror.org/00q6h8f30', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833', 'https://openalex.org/I911458345']}, {'id': 'https://openalex.org/I2802849423', 'display_name': 'University Medical Center', 'ror': 'https://ror.org/036pt7h44', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802849423']}, {'id': 'https://openalex.org/I4210108968', 'display_name': 'University Hospital and Clinics', 'ror': 'https://ror.org/013v7fk41', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210108968']}], 'countries': ['NL', 'US'], 'is_corresponding': False, 'raw_author_name': 'Viola Caretti', 'raw_affiliation_strings': ['Department of Pediatric Oncology, VU University Medical Center, Amsterdam.'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatric Oncology, VU University Medical Center, Amsterdam.', 'institution_ids': ['https://openalex.org/I911458345', 'https://openalex.org/I2802849423', 'https://openalex.org/I4210108968']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071718798', 'display_name': 'Ilse Zondervan', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ilse Zondervan', 'raw_affiliation_strings': ['Department of Neurosurgery'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5089767128', 'display_name': 'Dimphna H. Meijer', 'orcid': 'https://orcid.org/0000-0002-2010-8751'}, 'institutions': [{'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Dimphna H. Meijer', 'raw_affiliation_strings': ['Department of Cancer Biology, Harvard Medical School and Dana-Farber Cancer Institute'], 'affiliations': [{'raw_affiliation_string': 'Department of Cancer Biology, Harvard Medical School and Dana-Farber Cancer Institute', 'institution_ids': ['https://openalex.org/I136199984']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053305431', 'display_name': 'Sander Idema', 'orcid': 'https://orcid.org/0000-0001-7267-0255'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Sander Idema', 'raw_affiliation_strings': ['Department of Neurosurgery'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5105024566', 'display_name': 'Wim Vos', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wim Vos', 'raw_affiliation_strings': ['Department of Pathology'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048395521', 'display_name': 'Bob C. Hamans', 'orcid': 'https://orcid.org/0009-0002-2842-7674'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Bob Hamans', 'raw_affiliation_strings': ['Department of Radiology'], 'affiliations': [{'raw_affiliation_string': 'Department of Radiology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030595673', 'display_name': 'Marianna Bugiani', 'orcid': 'https://orcid.org/0000-0001-7689-3042'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Marianna Bugiani', 'raw_affiliation_strings': ['Department of Pathology'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5071910855', 'display_name': 'Esther Hulleman', 'orcid': 'https://orcid.org/0000-0001-9256-947X'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Esther Hulleman', 'raw_affiliation_strings': ['Department of Pediatric Oncology'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatric Oncology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5050961926', 'display_name': 'Pieter Wesseling', 'orcid': 'https://orcid.org/0000-0001-5453-5201'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'Pieter Wesseling', 'raw_affiliation_strings': ['Department of Pathology; Radboud University Nijmegen Medical Center; Nijmegen The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology; Radboud University Nijmegen Medical Center; Nijmegen The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5004632162', 'display_name': 'W. Peter Vandertop', 'orcid': 'https://orcid.org/0000-0001-5417-0265'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'W. Peter Vandertop', 'raw_affiliation_strings': ['Department of Neurosurgery'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5051927182', 'display_name': 'David P. Noske', 'orcid': 'https://orcid.org/0000-0001-5992-4468'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'David P. Noske', 'raw_affiliation_strings': ['Department of Neurosurgery'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5043037950', 'display_name': 'Gertjan J.L. Kaspers', 'orcid': 'https://orcid.org/0000-0001-7716-8475'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Gertjan Kaspers', 'raw_affiliation_strings': ['Department of Pediatric Oncology'], 'affiliations': [{'raw_affiliation_string': 'Department of Pediatric Oncology', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5035850924', 'display_name': 'Carla F.M. Molthoff', 'orcid': 'https://orcid.org/0000-0002-8838-8104'}, 'institutions': [{'id': 'https://openalex.org/I911458345', 'display_name': 'Amsterdam UMC Location VUmc', 'ror': 'https://ror.org/00q6h8f30', 'country_code': 'NL', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210151833', 'https://openalex.org/I911458345']}, {'id': 'https://openalex.org/I2802849423', 'display_name': 'University Medical Center', 'ror': 'https://ror.org/036pt7h44', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802849423']}, {'id': 'https://openalex.org/I4210108968', 'display_name': 'University Hospital and Clinics', 'ror': 'https://ror.org/013v7fk41', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210108968']}], 'countries': ['NL', 'US'], 'is_corresponding': False, 'raw_author_name': 'Carla F.M. Molthoff', 'raw_affiliation_strings': ['Nuclear Medicine & PET Research, VU University Medical Center, Amsterdam,'], 'affiliations': [{'raw_affiliation_string': 'Nuclear Medicine & PET Research, VU University Medical Center, Amsterdam,', 'institution_ids': ['https://openalex.org/I911458345', 'https://openalex.org/I2802849423', 'https://openalex.org/I4210108968']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5103044043', 'display_name': 'Thomas Würdinger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210087915', 'display_name': 'Massachusetts General Hospital', 'ror': 'https://ror.org/002pd6e78', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210087915', 'https://openalex.org/I48633490']}, {'id': 'https://openalex.org/I136199984', 'display_name': 'Harvard University', 'ror': 'https://ror.org/03vek6s52', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I136199984']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Thomas Wurdinger', 'raw_affiliation_strings': ['Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Ma'], 'affiliations': [{'raw_affiliation_string': 'Molecular Neurogenetics Unit, Department of Neurology, Massachusetts General Hospital and Harvard Medical School, Boston, Ma', 'institution_ids': ['https://openalex.org/I4210087915', 'https://openalex.org/I136199984']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 6, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3500, 'currency': 'USD', 'value_usd': 3500, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.074, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 56, 'citation_normalized_percentile': {'value': 0.92923, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '21', 'issue': '4', 'first_page': '441', 'last_page': '451'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10129', 'display_name': 'Glioma Diagnosis and Treatment', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11829', 'display_name': 'Mathematical Biology Tumor Growth', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/2611', 'display_name': 'Modeling and Simulation'}, 'field': {'id': 'https://openalex.org/fields/26', 'display_name': 'Mathematics'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10522', 'display_name': 'Medical Imaging Techniques and Applications', 'score': 0.9925, 'subfield': {'id': 'https://openalex.org/subfields/2741', 'display_name': 'Radiology, Nuclear Medicine and Imaging'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pons', 'display_name': 'Pons', 'score': 0.7338043}, {'id': 'https://openalex.org/keywords/nude-mouse', 'display_name': 'Nude mouse', 'score': 0.46543518}, {'id': 'https://openalex.org/keywords/mcherry', 'display_name': 'mCherry', 'score': 0.42227733}], 'concepts': [{'id': 'https://openalex.org/C2778897929', 'wikidata': 'https://www.wikidata.org/wiki/Q192570', 'display_name': 'Pons', 'level': 2, 'score': 0.7338043}, {'id': 'https://openalex.org/C2778227246', 'wikidata': 'https://www.wikidata.org/wiki/Q1365309', 'display_name': 'Glioma', 'level': 2, 'score': 0.66313887}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.58258355}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5420507}, {'id': 'https://openalex.org/C502942594', 'wikidata': 'https://www.wikidata.org/wiki/Q3421914', 'display_name': 'Cancer research', 'level': 1, 'score': 0.49081358}, {'id': 'https://openalex.org/C207001950', 'wikidata': 'https://www.wikidata.org/wiki/Q141124', 'display_name': 'In vivo', 'level': 2, 'score': 0.48901615}, {'id': 'https://openalex.org/C143409427', 'wikidata': 'https://www.wikidata.org/wiki/Q161238', 'display_name': 'Magnetic resonance imaging', 'level': 2, 'score': 0.47799698}, {'id': 'https://openalex.org/C2780278673', 'wikidata': 'https://www.wikidata.org/wiki/Q476743', 'display_name': 'Nude mouse', 'level': 3, 'score': 0.46543518}, {'id': 'https://openalex.org/C2779260011', 'wikidata': 'https://www.wikidata.org/wiki/Q412287', 'display_name': 'mCherry', 'level': 4, 'score': 0.42227733}, {'id': 'https://openalex.org/C2989005', 'wikidata': 'https://www.wikidata.org/wiki/Q214963', 'display_name': 'Nuclear medicine', 'level': 1, 'score': 0.3378855}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.26484066}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.23481289}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.19675806}, {'id': 'https://openalex.org/C142613039', 'wikidata': 'https://www.wikidata.org/wiki/Q272983', 'display_name': 'Green fluorescent protein', 'level': 3, 'score': 0.1500861}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.13983387}, {'id': 'https://openalex.org/C126838900', 'wikidata': 'https://www.wikidata.org/wiki/Q77604', 'display_name': 'Radiology', 'level': 1, 'score': 0.1253362}, {'id': 'https://openalex.org/C150903083', 'wikidata': 'https://www.wikidata.org/wiki/Q7108', 'display_name': 'Biotechnology', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D020295', 'descriptor_name': 'Brain Stem Neoplasms', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011149', 'descriptor_name': 'Pons', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020295', 'descriptor_name': 'Brain Stem Neoplasms', 'qualifier_ui': 'Q000532', 'qualifier_name': 'radiotherapy', 'is_major_topic': False}, {'descriptor_ui': 'D020295', 'descriptor_name': 'Brain Stem Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D045744', 'descriptor_name': 'Cell Line, Tumor', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007150', 'descriptor_name': 'Immunohistochemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D009364', 'descriptor_name': 'Neoplasm Recurrence, Local', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009368', 'descriptor_name': 'Neoplasm Transplantation', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D009368', 'descriptor_name': 'Neoplasm Transplantation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011149', 'descriptor_name': 'Pons', 'qualifier_ui': 'Q000528', 'qualifier_name': 'radiation effects', 'is_major_topic': False}, {'descriptor_ui': 'D011149', 'descriptor_name': 'Pons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011878', 'descriptor_name': 'Radiotherapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1750-3639.2010.00468.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S9094144', 'display_name': 'Brain Pathology', 'issn_l': '1015-6305', 'issn': ['1015-6305', '1750-3639'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094295', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21159008', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8094295', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.74, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 37, 'referenced_works': ['https://openalex.org/W1522048223', 'https://openalex.org/W1535449308', 'https://openalex.org/W1982740186', 'https://openalex.org/W1986845743', 'https://openalex.org/W1987934775', 'https://openalex.org/W1996878008', 'https://openalex.org/W2008171713', 'https://openalex.org/W2012469554', 'https://openalex.org/W2013620452', 'https://openalex.org/W2024020239', 'https://openalex.org/W2038591417', 'https://openalex.org/W2039442869', 'https://openalex.org/W2043293478', 'https://openalex.org/W2048042899', 'https://openalex.org/W2048043668', 'https://openalex.org/W2049943170', 'https://openalex.org/W2050912412', 'https://openalex.org/W2054694670', 'https://openalex.org/W2055665132', 'https://openalex.org/W2063426633', 'https://openalex.org/W2088352956', 'https://openalex.org/W2091486517', 'https://openalex.org/W2094589876', 'https://openalex.org/W2104551495', 'https://openalex.org/W2106263538', 'https://openalex.org/W2110687603', 'https://openalex.org/W2121765696', 'https://openalex.org/W2128774344', 'https://openalex.org/W2130552536', 'https://openalex.org/W2145013849', 'https://openalex.org/W2151311897', 'https://openalex.org/W2160692839', 'https://openalex.org/W2164459955', 'https://openalex.org/W2165464170', 'https://openalex.org/W2333730927', 'https://openalex.org/W3144725950', 'https://openalex.org/W3148267745'], 'related_works': ['https://openalex.org/W4385752706', 'https://openalex.org/W4223599704', 'https://openalex.org/W3173859282', 'https://openalex.org/W3032668952', 'https://openalex.org/W2593007003', 'https://openalex.org/W2418083954', 'https://openalex.org/W2092262588', 'https://openalex.org/W2072407675', 'https://openalex.org/W2049700149', 'https://openalex.org/W1978066089'], 'abstract_inverted_index': {'Abstract': [0], 'Diffuse': [1], 'intrinsic': [2], 'pontine': [3, 137], 'glioma': [4, 32, 138], '(DIPG)': [5], 'is': [6], 'a': [7, 24, 48, 56], 'fatal': [8], 'malignancy': [9], 'because': [10], 'of': [11, 23, 40, 55, 178, 203], 'its': [12], 'diffuse': [13, 60, 147, 168], 'infiltrative': [14, 150], 'growth': [15], 'pattern.': [16], 'Translational': [17], 'research': [18], 'suffers': [19], 'from': [20], 'the': [21, 38, 80, 100, 142, 146, 159, 181], 'lack': [22], 'representative': [25], 'DIPG': [26, 45, 57, 82, 110, 149, 197], 'animal': [27], 'model.': [28], 'Hence,': [29], 'human': [30], 'E98': [31, 44, 81, 103, 116, 148], 'cells': [33, 117, 134, 155], 'were': [34, 118, 156], 'stereotactically': [35], 'injected': [36, 140, 157], 'into': [37, 141, 158], 'pons': [39, 143, 160], 'nude': [41], 'mice.': [42], 'The': [43, 167], 'tumors': [46], 'presented': [47], 'strikingly': [49], 'similar': [50], 'histhopathology': [51], 'to': [52, 78, 98, 124, 174, 185], 'autopsy': [53], 'material': [54], 'patient,': [58], 'including': [59], 'and': [61, 65, 68, 122, 128], 'perivascular': [62], 'growth,': [63], 'brainstem‐': [64], 'supratentorial': [66], 'invasiveness': [67], 'leptomeningeal': [69], 'growth.': [70], 'Magnetic': [71], 'resonance': [72], 'imaging': [73, 95], '(MRI)': [74], 'was': [75, 96, 152, 171], 'effectively': [76], 'employed': [77], 'image': [79], 'tumor.': [83], '[': [84], '18': [85, 88], 'F]': [86], '3′‐deoxy‐3′‐[': [87], 'F]fluorothymidine': [89], '(FLT)': [90], 'positron': [91], 'emission': [92], 'tomography': [93], '(PET)': [94], 'applied': [97], 'assess': [99], 'subcutaneous': [101], '(s.c.)': [102], 'tumor': [104, 187], 'proliferation': [105], 'status': [106], 'but': [107], 'no': [108], 'orthotopic': [109], 'activity': [111], 'could': [112], 'be': [113, 202], 'visualized.': [114], 'Next,': [115], 'cultured': [119, 132], 'in': [120, 210], 'vitro': [121], 'engineered': [123], 'express': [125], 'firefly': [126], 'luciferase': [127], 'mCherry': [129], '(E98‐Fluc‐mCherry).': [130], 'These': [131], 'E98‐Fluc‐mCherry': [133, 169], 'developed': [135], 'focal': [136], 'when': [139, 154], 'directly.': [144], 'However,': [145], 'phenotype': [151], 'restored': [153], 'immediately': [161], 'after': [162], 'an': [163, 195], 'intermediate': [164], 's.c.': [165], 'passage.': [166], 'model': [170, 199], 'subsequently': [172], 'used': [173], 'test': [175], 'escalating': [176], 'doses': [177], 'irradiation,': [179], 'applying': [180], 'bioluminescent': [182], 'Fluc': [183], 'signal': [184], 'monitor': [186], 'recurrence': [188], 'over': [189], 'time.': [190], 'Altogether,': [191], 'we': [192], 'here': [193], 'describe': [194], 'accurate': [196], 'mouse': [198], 'that': [200], 'can': [201], 'clinical': [204], 'relevance': [205], 'for': [206], 'testing': [207], 'experimental': [208], 'therapeutics': [209], 'vivo': [211], '.': [212]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2101231917', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 8}, {'year': 2016, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 6}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 9}], 'updated_date': '2024-12-24T14:21:06.139177', 'created_date': '2016-06-24'}