Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2100241280', 'doi': 'https://doi.org/10.2217/pgs.11.131', 'title': 'Allopurinol Pharmacogenetics: Assessment of Potential Clinical Usefulness', 'display_name': 'Allopurinol Pharmacogenetics: Assessment of Potential Clinical Usefulness', 'publication_year': 2011, 'publication_date': '2011-11-25', 'ids': {'openalex': 'https://openalex.org/W2100241280', 'doi': 'https://doi.org/10.2217/pgs.11.131', 'mag': '2100241280', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/22118056'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.2217/pgs.11.131', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S190377370', 'display_name': 'Pharmacogenomics', 'issn_l': '1462-2416', 'issn': ['1462-2416', '1744-8042'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310321119', 'host_organization_name': 'Future Medicine', 'host_organization_lineage': ['https://openalex.org/P4310321119'], 'host_organization_lineage_names': ['Future Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://zenodo.org/records/1236437/files/article.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5043090391', 'display_name': 'Issam Zineh', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Issam Zineh', 'raw_affiliation_strings': ['Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA'], 'affiliations': [{'raw_affiliation_string': 'Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060584166', 'display_name': 'Padmaja Mummaneni', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Padmaja Mummaneni', 'raw_affiliation_strings': ['Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA'], 'affiliations': [{'raw_affiliation_string': 'Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019756658', 'display_name': 'Jenna Lyndly', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jenna Lyndly', 'raw_affiliation_strings': ['Division of Biostatistics VI, Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, Silver Spring, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Biostatistics VI, Office of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, Silver Spring, MD, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5083301167', 'display_name': 'Shashi Amur', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Shashi Amur', 'raw_affiliation_strings': ['Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA'], 'affiliations': [{'raw_affiliation_string': 'Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077083791', 'display_name': 'Lois A. La Grenade', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}, {'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Lois A La Grenade', 'raw_affiliation_strings': ['Division of Pharmacovigilance, Office of Surveillance & Epidemiology, Center for Drug Evaluation & Research, US FDA, Silver Spring, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Pharmacovigilance, Office of Surveillance & Epidemiology, Center for Drug Evaluation & Research, US FDA, Silver Spring, MD, USA', 'institution_ids': ['https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045553755', 'display_name': 'Stephen H. Chang', 'orcid': 'https://orcid.org/0000-0003-2245-732X'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Stephen H Chang', 'raw_affiliation_strings': ['Division of Epidemiology, Office of Surveillance & Epidemiology, Silver Spring, MD, USA'], 'affiliations': [{'raw_affiliation_string': 'Division of Epidemiology, Office of Surveillance & Epidemiology, Silver Spring, MD, USA', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5036876946', 'display_name': 'Hobart Rogers', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hobart Rogers', 'raw_affiliation_strings': ['Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA'], 'affiliations': [{'raw_affiliation_string': 'Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5069686574', 'display_name': 'Michael Pacanowski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1333606569', 'display_name': 'Center for Drug Evaluation and Research', 'ror': 'https://ror.org/00yf3tm42', 'country_code': 'US', 'type': 'facility', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070', 'https://openalex.org/I1333606569']}, {'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Michael A Pacanowski', 'raw_affiliation_strings': ['Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA'], 'affiliations': [{'raw_affiliation_string': 'Genomics Group, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation & Research, US FDA, 10903 New Hampshire Avenue, Silver Spring, MD, 20993, USA', 'institution_ids': ['https://openalex.org/I1333606569', 'https://openalex.org/I1320320070']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 3.064, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 36, 'citation_normalized_percentile': {'value': 0.830471, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '12', 'issue': '12', 'first_page': '1741', 'last_page': '1749'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11117', 'display_name': 'Drug-Induced Adverse Reactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11117', 'display_name': 'Drug-Induced Adverse Reactions', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10151', 'display_name': 'Hepatitis C virus research', 'score': 0.9926, 'subfield': {'id': 'https://openalex.org/subfields/2721', 'display_name': 'Hepatology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10625', 'display_name': 'Herpesvirus Infections and Treatments', 'score': 0.9918, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/allopurinol', 'display_name': 'Allopurinol', 'score': 0.97477627}], 'concepts': [{'id': 'https://openalex.org/C2780261098', 'wikidata': 'https://www.wikidata.org/wiki/Q412486', 'display_name': 'Allopurinol', 'level': 2, 'score': 0.97477627}, {'id': 'https://openalex.org/C55775858', 'wikidata': 'https://www.wikidata.org/wiki/Q1152227', 'display_name': 'Pharmacogenetics', 'level': 4, 'score': 0.8540662}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.7460691}, {'id': 'https://openalex.org/C197934379', 'wikidata': 'https://www.wikidata.org/wiki/Q2047938', 'display_name': 'Adverse effect', 'level': 2, 'score': 0.65699255}, {'id': 'https://openalex.org/C177713679', 'wikidata': 'https://www.wikidata.org/wiki/Q679690', 'display_name': 'Intensive care medicine', 'level': 1, 'score': 0.5310006}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.34226793}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28762358}, {'id': 'https://openalex.org/C135763542', 'wikidata': 'https://www.wikidata.org/wiki/Q106016', 'display_name': 'Genotype', 'level': 3, 'score': 0.2602222}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.07898906}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.070177466}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000493', 'descriptor_name': 'Allopurinol', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D005820', 'descriptor_name': 'Genetic Testing', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D014644', 'descriptor_name': 'Genetic Variation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D006074', 'descriptor_name': 'Gout Suppressants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D012871', 'descriptor_name': 'Skin Diseases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000369', 'descriptor_name': 'Aged, 80 and over', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000493', 'descriptor_name': 'Allopurinol', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D000493', 'descriptor_name': 'Allopurinol', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004892', 'descriptor_name': 'Erythema Multiforme', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D004892', 'descriptor_name': 'Erythema Multiforme', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D004892', 'descriptor_name': 'Erythema Multiforme', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056726', 'descriptor_name': 'Genetic Association Studies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005820', 'descriptor_name': 'Genetic Testing', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006073', 'descriptor_name': 'Gout', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D006073', 'descriptor_name': 'Gout', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006074', 'descriptor_name': 'Gout Suppressants', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': False}, {'descriptor_ui': 'D006074', 'descriptor_name': 'Gout Suppressants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006680', 'descriptor_name': 'HLA Antigens', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D033461', 'descriptor_name': 'Hyperuricemia', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D033461', 'descriptor_name': 'Hyperuricemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010597', 'descriptor_name': 'Pharmacogenetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018570', 'descriptor_name': 'Risk Assessment', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012871', 'descriptor_name': 'Skin Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012871', 'descriptor_name': 'Skin Diseases', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000139', 'qualifier_name': 'chemically induced', 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}, {'descriptor_ui': 'D013262', 'descriptor_name': 'Stevens-Johnson Syndrome', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.2217/pgs.11.131', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S190377370', 'display_name': 'Pharmacogenomics', 'issn_l': '1462-2416', 'issn': ['1462-2416', '1744-8042'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310321119', 'host_organization_name': 'Future Medicine', 'host_organization_lineage': ['https://openalex.org/P4310321119'], 'host_organization_lineage_names': ['Future Medicine'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://zenodo.org/record/1236437', 'pdf_url': 'https://zenodo.org/records/1236437/files/article.pdf', 'source': {'id': 'https://openalex.org/S4306400562', 'display_name': 'Zenodo (CERN European Organization for Nuclear Research)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I67311998', 'host_organization_name': 'European Organization for Nuclear Research', 'host_organization_lineage': ['https://openalex.org/I67311998'], 'host_organization_lineage_names': ['European Organization for Nuclear Research'], 'type': 'repository'}, 'license': 'public-domain', 'license_id': 'https://openalex.org/licenses/public-domain', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/22118056', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://zenodo.org/record/1236437', 'pdf_url': 'https://zenodo.org/records/1236437/files/article.pdf', 'source': {'id': 'https://openalex.org/S4306400562', 'display_name': 'Zenodo (CERN European Organization for Nuclear Research)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I67311998', 'host_organization_name': 'European Organization for Nuclear Research', 'host_organization_lineage': ['https://openalex.org/I67311998'], 'host_organization_lineage_names': ['European Organization for Nuclear Research'], 'type': 'repository'}, 'license': 'public-domain', 'license_id': 'https://openalex.org/licenses/public-domain', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/16', 'score': 0.69, 'display_name': 'Peace, justice, and strong institutions'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 20, 'referenced_works': ['https://openalex.org/W1969692023', 'https://openalex.org/W1976143261', 'https://openalex.org/W1981809734', 'https://openalex.org/W2006571705', 'https://openalex.org/W2025161685', 'https://openalex.org/W2036592937', 'https://openalex.org/W2042786638', 'https://openalex.org/W2051943670', 'https://openalex.org/W2059087939', 'https://openalex.org/W2077675427', 'https://openalex.org/W2083508836', 'https://openalex.org/W2083991698', 'https://openalex.org/W2089689254', 'https://openalex.org/W2099748786', 'https://openalex.org/W2125435699', 'https://openalex.org/W2150169647', 'https://openalex.org/W2151809600', 'https://openalex.org/W2155931624', 'https://openalex.org/W2324138493', 'https://openalex.org/W2464469971'], 'related_works': ['https://openalex.org/W999601946', 'https://openalex.org/W619739265', 'https://openalex.org/W3080085317', 'https://openalex.org/W2411406515', 'https://openalex.org/W2144496194', 'https://openalex.org/W2100241280', 'https://openalex.org/W2084675528', 'https://openalex.org/W2061706865', 'https://openalex.org/W1967577043', 'https://openalex.org/W1878162582'], 'abstract_inverted_index': {'Use': [0], 'of': [1, 50, 71, 82, 93, 101, 118], 'pharmacogenetics': [2], 'to': [3, 33, 44, 46, 88], 'inform': [4], 'treatment': [5], 'decisions': [6], 'remains': [7], 'a': [8, 20], 'priority': [9], 'for': [10, 22, 57], 'clinicians,': [11], 'patients': [12, 94], 'and': [13, 36, 68, 106, 112], 'public': [14], 'health': [15], 'agencies.': [16], 'We': [17, 40, 63], 'previously': [18], 'developed': [19], 'framework': [21], 'systematically': [23], 'assessing': [24, 55], 'whether': [25, 90], 'pharmacogenetic': [26], 'test': [27], 'information': [28, 53], 'would': [29], 'likely': [30], 'bring': [31], 'value': [32], 'clinical': [34, 91, 116], 'decision-making': [35], 'enjoy': [37], 'practical': [38], 'uptake.': [39], 'applied': [41], 'this': [42], 'tool': [43], 'allopurinol': [45, 65, 119], 'determine': [47], 'potential': [48], 'usefulness': [49], 'HLA': [51, 104], 'genetic': [52], 'in': [54, 115], 'risk': [56], 'allopurinol-induced': [58, 107], 'severe': [59, 84, 108], 'cutaneous': [60, 85, 109], 'adverse': [61, 72, 86, 110], 'reactions.': [62], 'quantified': [64], 'use': [66], 'data': [67], 'the': [69], 'magnitude': [70], 'event': [73], 'signals': [74], 'using': [75], 'US': [76], 'FDA': [77], 'databases,': [78], 'reviewed': [79], 'reported': [80], 'cases': [81], 'allopurinol-associated': [83], 'reactions': [87, 111], 'assess': [89], 'subtypes': [92], 'could': [95], 'be': [96], 'identified,': [97], 'performed': [98], 'pooled': [99], 'analyses': [100], 'associations': [102], 'between': [103], 'variation': [105], 'described': [113], 'considerations': [114], 'implementation': [117], 'pharmacogenetics.': [120]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2100241280', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 4}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 6}, {'year': 2015, 'cited_by_count': 4}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 7}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-12-14T14:37:15.618025', 'created_date': '2016-06-24'}