Publication Information

{'id': 'https://openalex.org/W2100072399', 'doi': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'title': 'A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs', 'display_name': 'A Chimeric Porcine Circovirus (PCV) with the Immunogenic Capsid Gene of the Pathogenic PCV Type 2 (PCV2) Cloned into the Genomic Backbone of the Nonpathogenic PCV1 Induces Protective Immunity against PCV2 Infection in Pigs', 'publication_year': 2004, 'publication_date': '2004-05-26', 'ids': {'openalex': 'https://openalex.org/W2100072399', 'doi': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'mag': '2100072399', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15163723', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/416547'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5063060954', 'display_name': 'Martijn Fenaux', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I39822340', 'display_name': 'Virginia–Maryland College of Veterinary Medicine', 'ror': 'https://ror.org/010prmy50', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39822340', 'https://openalex.org/I66946132', 'https://openalex.org/I859038795']}, {'id': 'https://openalex.org/I859038795', 'display_name': 'Virginia Tech', 'ror': 'https://ror.org/02smfhw86', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I859038795']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'M. Fenaux', 'raw_affiliation_strings': ['Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0342, USA'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomedical Sciences and Pathobiology, Center for Molecular Medicine and Infectious Diseases, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA 24061-0342, USA', 'institution_ids': ['https://openalex.org/I39822340', 'https://openalex.org/I859038795']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5076424727', 'display_name': 'Tanja Opriessnig', 'orcid': 'https://orcid.org/0000-0001-9642-0904'}, 'institutions': [{'id': 'https://openalex.org/I173911158', 'display_name': 'Iowa State University', 'ror': 'https://ror.org/04rswrd78', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I173911158']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'T. Opriessnig', 'raw_affiliation_strings': ['Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011'], 'affiliations': [{'raw_affiliation_string': 'Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011', 'institution_ids': ['https://openalex.org/I173911158']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027162909', 'display_name': 'Patrick G. Halbur', 'orcid': 'https://orcid.org/0000-0003-0294-821X'}, 'institutions': [{'id': 'https://openalex.org/I173911158', 'display_name': 'Iowa State University', 'ror': 'https://ror.org/04rswrd78', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I173911158']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'P. G. Halbur', 'raw_affiliation_strings': ['Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011'], 'affiliations': [{'raw_affiliation_string': 'Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, Iowa 50011', 'institution_ids': ['https://openalex.org/I173911158']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5066851512', 'display_name': 'François Elvinger', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I859038795', 'display_name': 'Virginia Tech', 'ror': 'https://ror.org/02smfhw86', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I859038795']}, {'id': 'https://openalex.org/I39822340', 'display_name': 'Virginia–Maryland College of Veterinary Medicine', 'ror': 'https://ror.org/010prmy50', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I39822340', 'https://openalex.org/I66946132', 'https://openalex.org/I859038795']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'F. Elvinger', 'raw_affiliation_strings': ['Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0342'], 'affiliations': [{'raw_affiliation_string': 'Department of Large Animal Clinical Sciences, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia 24061-0342', 'institution_ids': ['https://openalex.org/I859038795', 'https://openalex.org/I39822340']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5075780100', 'display_name': 'Xiang‐Jin Meng', 'orcid': 'https://orcid.org/0000-0002-2739-1334'}, 'institutions': [{'id': 'https://openalex.org/I4210131484', 'display_name': 'Center for Molecular Medicine and Immunology', 'ror': 'https://ror.org/03fhjvs31', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I4210131484']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'X. J. Meng', 'raw_affiliation_strings': ['Center for Molecular Medicine and Infectious Diseases'], 'affiliations': [{'raw_affiliation_string': 'Center for Molecular Medicine and Infectious Diseases', 'institution_ids': ['https://openalex.org/I4210131484']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 13.068, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 206, 'citation_normalized_percentile': {'value': 0.999722, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '78', 'issue': '12', 'first_page': '6297', 'last_page': '6303'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11495', 'display_name': 'Animal Virus Infections Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1103', 'display_name': 'Animal Science and Zoology'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11495', 'display_name': 'Animal Virus Infections Studies', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1103', 'display_name': 'Animal Science and Zoology'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10613', 'display_name': 'Virus-based gene therapy research', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/circovirus', 'display_name': 'Circovirus', 'score': 0.8489173}, {'id': 'https://openalex.org/keywords/viremia', 'display_name': 'Viremia', 'score': 0.48496556}], 'concepts': [{'id': 'https://openalex.org/C2781045504', 'wikidata': 'https://www.wikidata.org/wiki/Q128578', 'display_name': 'Porcine circovirus', 'level': 3, 'score': 0.98062384}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.9045128}, {'id': 'https://openalex.org/C2779231742', 'wikidata': 'https://www.wikidata.org/wiki/Q5121560', 'display_name': 'Circovirus', 'level': 4, 'score': 0.8489173}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.84423566}, {'id': 'https://openalex.org/C202878990', 'wikidata': 'https://www.wikidata.org/wiki/Q830465', 'display_name': 'Capsid', 'level': 3, 'score': 0.5932025}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.5184607}, {'id': 'https://openalex.org/C2779341262', 'wikidata': 'https://www.wikidata.org/wiki/Q182581', 'display_name': 'Immunity', 'level': 3, 'score': 0.5072498}, {'id': 'https://openalex.org/C167508917', 'wikidata': 'https://www.wikidata.org/wiki/Q578537', 'display_name': 'DNA vaccination', 'level': 4, 'score': 0.48689213}, {'id': 'https://openalex.org/C2776185481', 'wikidata': 'https://www.wikidata.org/wiki/Q1425304', 'display_name': 'Viremia', 'level': 3, 'score': 0.48496556}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.46900865}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.384995}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.24291104}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.20261556}, {'id': 'https://openalex.org/C2780801004', 'wikidata': 'https://www.wikidata.org/wiki/Q1415366', 'display_name': 'Immunization', 'level': 3, 'score': 0.18661228}], 'mesh': [{'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': 'Q000097', 'qualifier_name': 'blood', 'is_major_topic': True}, {'descriptor_ui': 'D002213', 'descriptor_name': 'Capsid', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D017925', 'descriptor_name': 'Circovirus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D013553', 'descriptor_name': 'Swine Diseases', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D014765', 'descriptor_name': 'Viral Vaccines', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000914', 'descriptor_name': 'Antibodies, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D000956', 'descriptor_name': 'Antigens, Viral', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D002213', 'descriptor_name': 'Capsid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018173', 'descriptor_name': 'Circoviridae Infections', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018173', 'descriptor_name': 'Circoviridae Infections', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D018173', 'descriptor_name': 'Circoviridae Infections', 'qualifier_ui': 'Q000662', 'qualifier_name': 'veterinary', 'is_major_topic': False}, {'descriptor_ui': 'D018173', 'descriptor_name': 'Circoviridae Infections', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D017925', 'descriptor_name': 'Circovirus', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': False}, {'descriptor_ui': 'D017925', 'descriptor_name': 'Circovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017925', 'descriptor_name': 'Circovirus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D003001', 'descriptor_name': 'Cloning, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013552', 'descriptor_name': 'Swine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013553', 'descriptor_name': 'Swine Diseases', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D013553', 'descriptor_name': 'Swine Diseases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014611', 'descriptor_name': 'Vaccination', 'qualifier_ui': 'Q000662', 'qualifier_name': 'veterinary', 'is_major_topic': False}, {'descriptor_ui': 'D014611', 'descriptor_name': 'Vaccination', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014613', 'descriptor_name': 'Vaccines, Attenuated', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D014613', 'descriptor_name': 'Vaccines, Attenuated', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014613', 'descriptor_name': 'Vaccines, Attenuated', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D014613', 'descriptor_name': 'Vaccines, Attenuated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014765', 'descriptor_name': 'Viral Vaccines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014765', 'descriptor_name': 'Viral Vaccines', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D014765', 'descriptor_name': 'Viral Vaccines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D019282', 'descriptor_name': 'Wasting Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019282', 'descriptor_name': 'Wasting Syndrome', 'qualifier_ui': 'Q000821', 'qualifier_name': 'virology', 'is_major_topic': False}, {'descriptor_ui': 'D019282', 'descriptor_name': 'Wasting Syndrome', 'qualifier_ui': 'Q000662', 'qualifier_name': 'veterinary', 'is_major_topic': False}, {'descriptor_ui': 'D019282', 'descriptor_name': 'Wasting Syndrome', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': False}, {'descriptor_ui': 'D014886', 'descriptor_name': 'Weaning', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/20.500.11820/ed5671f4-0ac5-4d72-9486-8568caf736ad', 'pdf_url': 'https://www.research.ed.ac.uk/files/10725315/A_chimeric_porcine_circovirus_PCV_with_the_immunogenic_capsid_gene_of_the_pathogenic_PCV_type_2_PCV2_cloned_into_the_genomic_backbone.pdf', 'source': {'id': 'https://openalex.org/S4306400321', 'display_name': 'Edinburgh Research Explorer (University of Edinburgh)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I98677209', 'host_organization_name': 'University of Edinburgh', 'host_organization_lineage': ['https://openalex.org/I98677209'], 'host_organization_lineage_names': ['University of Edinburgh'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.pure.ed.ac.uk/ws/files/10725315/A_chimeric_porcine_circovirus_PCV_with_the_immunogenic_capsid_gene_of_the_pathogenic_PCV_type_2_PCV2_cloned_into_the_genomic_backbone.pdf', 'pdf_url': 'https://www.pure.ed.ac.uk/ws/files/10725315/A_chimeric_porcine_circovirus_PCV_with_the_immunogenic_capsid_gene_of_the_pathogenic_PCV_type_2_PCV2_cloned_into_the_genomic_backbone.pdf', 'source': {'id': 'https://openalex.org/S4306400321', 'display_name': 'Edinburgh Research Explorer (University of Edinburgh)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I98677209', 'host_organization_name': 'University of Edinburgh', 'host_organization_lineage': ['https://openalex.org/I98677209'], 'host_organization_lineage_names': ['University of Edinburgh'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc416547', 'pdf_url': 'https://europepmc.org/articles/pmc416547?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC416547', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15163723', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1128/jvi.78.12.6297-6303.2004', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S96615428', 'display_name': 'Journal of Virology', 'issn_l': '0022-538X', 'issn': ['0022-538X', '1070-6321', '1098-5514'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320263', 'host_organization_name': 'American Society for Microbiology', 'host_organization_lineage': ['https://openalex.org/P4310320263'], 'host_organization_lineage_names': ['American Society for Microbiology'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'score': 0.64, 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 39, 'referenced_works': ['https://openalex.org/W1588161542', 'https://openalex.org/W1976992846', 'https://openalex.org/W1977367063', 'https://openalex.org/W1977563342', 'https://openalex.org/W1979824682', 'https://openalex.org/W1983170246', 'https://openalex.org/W1999086554', 'https://openalex.org/W2002924510', 'https://openalex.org/W2004846466', 'https://openalex.org/W2005542324', 'https://openalex.org/W2006772396', 'https://openalex.org/W2017194433', 'https://openalex.org/W2025948291', 'https://openalex.org/W2034835251', 'https://openalex.org/W2035108540', 'https://openalex.org/W2038264706', 'https://openalex.org/W2043580526', 'https://openalex.org/W2045301088', 'https://openalex.org/W2055556815', 'https://openalex.org/W2065974702', 'https://openalex.org/W2080647938', 'https://openalex.org/W2097112899', 'https://openalex.org/W2109494233', 'https://openalex.org/W2109938430', 'https://openalex.org/W2119165547', 'https://openalex.org/W2126468098', 'https://openalex.org/W2127521024', 'https://openalex.org/W2127885339', 'https://openalex.org/W2140296277', 'https://openalex.org/W2143211788', 'https://openalex.org/W2145995554', 'https://openalex.org/W2148748484', 'https://openalex.org/W2153314219', 'https://openalex.org/W2155891786', 'https://openalex.org/W2160693757', 'https://openalex.org/W2165426944', 'https://openalex.org/W2166812685', 'https://openalex.org/W2168569754', 'https://openalex.org/W2514354147'], 'related_works': ['https://openalex.org/W4389342439', 'https://openalex.org/W4297611268', 'https://openalex.org/W4281297952', 'https://openalex.org/W3149237550', 'https://openalex.org/W3010556497', 'https://openalex.org/W3006604974', 'https://openalex.org/W2774652537', 'https://openalex.org/W2387516442', 'https://openalex.org/W2132789796', 'https://openalex.org/W2092374783'], 'abstract_inverted_index': {'ABSTRACT': [0], 'Porcine': [1], 'circovirus': [2], 'type': [3], '2': [4, 111, 190], '(PCV2)': [5], 'is': [6, 17, 50], 'associated': [7], 'with': [8, 98, 117, 136, 189], 'postweaning': [9], 'multisystemic': [10], 'wasting': [11], 'syndrome': [12], 'in': [13, 52, 69, 90, 109, 128, 154, 221, 239, 259, 268, 278, 286, 301, 304, 313, 333], 'pigs,': [14, 334], 'whereas': [15], 'PCV1': [16], 'nonpathogenic.': [18], 'We': [19], 'previously': [20], 'demonstrated': [21], 'that': [22, 57, 329], 'a': [23, 121, 197, 315], 'chimeric': [24, 60, 103, 122, 149, 337, 345], 'PCV1-2': [25, 61, 104, 123, 150, 338, 346], 'virus': [26], '(with': [27], 'the': [28, 36, 45, 58, 102, 148, 169, 210, 236, 240, 305, 335, 344], 'immunogenic': [29], 'capsid': [30, 47, 177], 'gene': [31], 'of': [32, 38, 73, 85, 101, 120, 147, 171, 196, 209, 251, 273, 282, 289, 307], 'PCV2': [33, 46, 67, 176, 200, 229, 255, 274, 354], 'cloned': [34], 'into': [35], 'backbone': [37], 'PCV1)': [39], 'induces': [40, 62, 350], 'an': [41, 361], 'antibody': [42], 'response': [43], 'to': [44, 65, 82, 175, 224, 320], 'protein': [48], 'and': [49, 79, 160, 187, 296, 356], 'attenuated': [51, 59, 336], 'pigs.': [53, 70, 253, 270, 292, 322], 'Here,': [54], 'we': [55], 'report': [56], 'protective': [63, 351], 'immunity': [64, 352], 'wild-type': [66, 198], 'challenge': [68], 'A': [71], 'total': [72], '48': [74], 'specific-pathogen-free': [75], 'piglets': [76], 'were': [77, 93, 112, 131, 157, 184, 215, 243, 262, 276, 299], 'randomly': [78], 'equally': [80], 'assigned': [81], 'four': [83], 'groups': [84, 222], '12': [86, 211], 'pigs': [87, 172, 183, 214, 242, 284, 311], 'each.': [88], 'Pigs': [89, 108, 127, 153], 'group': [91, 110, 129, 155, 212, 309, 318], '1': [92, 223, 288, 319], 'vaccinated': [94, 113, 132, 159, 252, 269, 291, 317], 'by': [95, 114, 133], 'intramuscular': [96, 134], 'injection': [97, 116, 135], '200': [99, 118], 'μg': [100, 119], 'infectious': [105, 124, 347], 'DNA': [106, 125, 348], 'clone.': [107, 126], 'intralymphoid': [115], '3': [130, 225, 321], '10': [137, 192], '3.5': [138], '50%': [139], 'tissue': [140], 'culture': [141], 'infective': [142], 'doses': [143], '(TCID': [144], '50': [145, 195], ')': [146], 'live': [151, 339], 'virus.': [152, 201], '4': [156, 213, 310], 'not': [158], 'served': [161], 'as': [162, 341, 343, 360], 'controls.': [163], 'By': [164, 202], '42': [165, 180], 'days': [166, 204], 'postvaccination': [167], '(DPV),': [168], 'majority': [170, 306], 'had': [173, 226], 'seroconverted': [174], 'antibody.': [178], 'At': [179, 233], 'DPV,': [181], 'all': [182], 'challenged': [185], 'intranasally': [186], 'intramuscularly': [188, 332], '×': [191], '4.5': [193], 'TCID': [194], 'pathogenic': [199], '21': [203, 234], 'postchallenge': [205], '(DPC),': [206], '9': [207], 'out': [208], 'viremic': [216], 'for': [217], 'PCV2.': [218], 'Vaccinated': [219], 'animals': [220], 'no': [227], 'detectable': [228], 'viremia': [230], 'after': [231], 'challenge.': [232], 'DPC': [235], 'lymph': [237, 260], 'nodes': [238, 261], 'nonvaccinated': [241, 283, 308], 'larger': [244], '(': [245, 264], 'P': [246, 265], '<': [247, 266], '0.05)': [248], 'than': [249], 'those': [250], 'The': [254, 323], 'genomic': [256], 'copy': [257], 'loads': [258], 'reduced': [263], '0.0001)': [267], 'Moderate': [271], 'amounts': [272], 'antigen': [275], 'detected': [277, 300], 'most': [279], 'lymphoid': [280, 294, 302], 'tissues': [281, 303], 'but': [285, 312], 'only': [287, 314], '36': [290], 'Mild-to-severe': [293], 'depletion': [295], 'histiocytic': [297], 'replacement': [298], 'few': [316], 'data': [324], 'from': [325], 'this': [326], 'study': [327], 'indicated': [328], 'when': [330], 'given': [331], 'virus,': [340], 'well': [342], 'clone,': [349], 'against': [353], 'infection': [355], 'could': [357], 'potentially': [358], 'serve': [359], 'effective': [362], 'vaccine.': [363]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2100072399', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 8}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 5}, {'year': 2017, 'cited_by_count': 6}, {'year': 2016, 'cited_by_count': 11}, {'year': 2015, 'cited_by_count': 9}, {'year': 2014, 'cited_by_count': 8}, {'year': 2013, 'cited_by_count': 5}, {'year': 2012, 'cited_by_count': 23}], 'updated_date': '2024-12-18T23:42:48.271207', 'created_date': '2016-06-24'}