Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2099346887', 'doi': 'https://doi.org/10.1007/bf00422365', 'title': 'Reduction of heparan sulphate-associated anionic sites in the glomerular basement membrane of rats with streptozotocin-induced diabetic nephropathy', 'display_name': 'Reduction of heparan sulphate-associated anionic sites in the glomerular basement membrane of rats with streptozotocin-induced diabetic nephropathy', 'publication_year': 1995, 'publication_date': '1995-10-01', 'ids': {'openalex': 'https://openalex.org/W2099346887', 'doi': 'https://doi.org/10.1007/bf00422365', 'mag': '2099346887', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8690168'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/bf00422365', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/BF00422365.pdf', 'source': {'id': 'https://openalex.org/S104375418', 'display_name': 'Diabetologia', 'issn_l': '0012-186X', 'issn': ['0012-186X', '1432-0428'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://link.springer.com/content/pdf/10.1007/BF00422365.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5105932764', 'display_name': 'Jacob van den Born', 'orcid': 'https://orcid.org/0000-0002-7883-5361'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'J. van den Born', 'raw_affiliation_strings': ['Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5060509962', 'display_name': 'Annemieke A. van Kraats', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'A. A. van Kraats', 'raw_affiliation_strings': ['Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5037625247', 'display_name': 'Marinka A.H. Bakker', 'orcid': 'https://orcid.org/0000-0002-1947-8747'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'M. A. H. Bakker', 'raw_affiliation_strings': ['Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103510640', 'display_name': 'K J Assmann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'K. J. M. Assmann', 'raw_affiliation_strings': ['Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052715853', 'display_name': 'Henry Dijkman', 'orcid': 'https://orcid.org/0000-0002-4924-6859'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'H. B. P. M. Dijkman', 'raw_affiliation_strings': ['Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081003438', 'display_name': 'Jeroen van der Laak', 'orcid': 'https://orcid.org/0000-0001-7982-0754'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'J. A. W. M. van der Laak', 'raw_affiliation_strings': ['Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathology, University Hospital St. Radboud, Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5014634963', 'display_name': 'Jo H. M. Berden', 'orcid': 'https://orcid.org/0000-0002-3562-9445'}, 'institutions': [{'id': 'https://openalex.org/I145872427', 'display_name': 'Radboud University Nijmegen', 'ror': 'https://ror.org/016xsfp80', 'country_code': 'NL', 'type': 'education', 'lineage': ['https://openalex.org/I145872427']}], 'countries': ['NL'], 'is_corresponding': False, 'raw_author_name': 'J. H. M. Berden', 'raw_affiliation_strings': ['Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands'], 'affiliations': [{'raw_affiliation_string': 'Department of Nephrology, University Hospital St. Radboud, HB Nijmegen, The Netherlands', 'institution_ids': ['https://openalex.org/I145872427']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3890, 'currency': 'EUR', 'value_usd': 4990, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.583, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 47, 'citation_normalized_percentile': {'value': 0.795661, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '38', 'issue': '10', 'first_page': '1169', 'last_page': '1175'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11131', 'display_name': 'Role of Extracellular Matrix in Biological Signaling', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11131', 'display_name': 'Role of Extracellular Matrix in Biological Signaling', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11142', 'display_name': 'Biochemistry of Diabetic Complications', 'score': 0.9951, 'subfield': {'id': 'https://openalex.org/subfields/1308', 'display_name': 'Clinical Biochemistry'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11908', 'display_name': 'Protein Binding Specificity in Human Serum Albumin', 'score': 0.9929, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/lamina-densa', 'display_name': 'Lamina densa', 'score': 0.973276}, {'id': 'https://openalex.org/keywords/lamina-lucida', 'display_name': 'Lamina lucida', 'score': 0.9043776}, {'id': 'https://openalex.org/keywords/perlecan', 'display_name': 'Perlecan', 'score': 0.58409625}, {'id': 'https://openalex.org/keywords/heparan-sulfate', 'display_name': 'Heparan Sulfate', 'score': 0.485103}], 'concepts': [{'id': 'https://openalex.org/C3060791', 'wikidata': 'https://www.wikidata.org/wiki/Q3216737', 'display_name': 'Lamina densa', 'level': 3, 'score': 0.973276}, {'id': 'https://openalex.org/C44843598', 'wikidata': 'https://www.wikidata.org/wiki/Q6481904', 'display_name': 'Lamina lucida', 'level': 4, 'score': 0.9043776}, {'id': 'https://openalex.org/C2776193487', 'wikidata': 'https://www.wikidata.org/wiki/Q32846', 'display_name': 'Basement membrane', 'level': 2, 'score': 0.82299995}, {'id': 'https://openalex.org/C2776115139', 'wikidata': 'https://www.wikidata.org/wiki/Q1753456', 'display_name': 'Glomerular basement membrane', 'level': 4, 'score': 0.80571866}, {'id': 'https://openalex.org/C22731427', 'wikidata': 'https://www.wikidata.org/wiki/Q2071346', 'display_name': 'Perlecan', 'level': 4, 'score': 0.58409625}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.56141794}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.5062777}, {'id': 'https://openalex.org/C74864618', 'wikidata': 'https://www.wikidata.org/wiki/Q2332446', 'display_name': 'Staining', 'level': 2, 'score': 0.50381273}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4982872}, {'id': 'https://openalex.org/C2779280383', 'wikidata': 'https://www.wikidata.org/wiki/Q257331', 'display_name': 'Streptozotocin', 'level': 3, 'score': 0.48992413}, {'id': 'https://openalex.org/C2779922275', 'wikidata': 'https://www.wikidata.org/wiki/Q1129105', 'display_name': 'Diabetic nephropathy', 'level': 3, 'score': 0.47960198}, {'id': 'https://openalex.org/C153074725', 'wikidata': 'https://www.wikidata.org/wiki/Q407553', 'display_name': 'Glycosaminoglycan', 'level': 2, 'score': 0.3992319}, {'id': 'https://openalex.org/C2778041096', 'wikidata': 'https://www.wikidata.org/wiki/Q424668', 'display_name': 'Heparan sulfate', 'level': 3, 'score': 0.3686443}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2763782}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.26673934}, {'id': 'https://openalex.org/C555293320', 'wikidata': 'https://www.wikidata.org/wiki/Q12206', 'display_name': 'Diabetes mellitus', 'level': 2, 'score': 0.26283646}, {'id': 'https://openalex.org/C2780091579', 'wikidata': 'https://www.wikidata.org/wiki/Q9377', 'display_name': 'Kidney', 'level': 2, 'score': 0.25586915}, {'id': 'https://openalex.org/C105702510', 'wikidata': 'https://www.wikidata.org/wiki/Q514', 'display_name': 'Anatomy', 'level': 1, 'score': 0.24091846}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.19158131}, {'id': 'https://openalex.org/C189165786', 'wikidata': 'https://www.wikidata.org/wiki/Q193825', 'display_name': 'Extracellular matrix', 'level': 2, 'score': 0.17930841}, {'id': 'https://openalex.org/C2779814568', 'wikidata': 'https://www.wikidata.org/wiki/Q58345', 'display_name': 'Laminin', 'level': 3, 'score': 0.15138692}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.14782059}, {'id': 'https://openalex.org/C2780368995', 'wikidata': 'https://www.wikidata.org/wiki/Q605006', 'display_name': 'Glomerulonephritis', 'level': 3, 'score': 0.14106053}], 'mesh': [{'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D003928', 'descriptor_name': 'Diabetic Nephropathies', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006497', 'descriptor_name': 'Heparitin Sulfate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D007678', 'descriptor_name': 'Kidney Glomerulus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000419', 'descriptor_name': 'Albuminuria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000704', 'descriptor_name': 'Analysis of Variance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000838', 'descriptor_name': 'Anions', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D001485', 'descriptor_name': 'Basement Membrane', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001786', 'descriptor_name': 'Blood Glucose', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002808', 'descriptor_name': 'Chondroitin Lyases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004396', 'descriptor_name': 'Coloring Agents', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003921', 'descriptor_name': 'Diabetes Mellitus, Experimental', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003928', 'descriptor_name': 'Diabetic Nephropathies', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D003928', 'descriptor_name': 'Diabetic Nephropathies', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006497', 'descriptor_name': 'Heparitin Sulfate', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D006497', 'descriptor_name': 'Heparitin Sulfate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007678', 'descriptor_name': 'Kidney Glomerulus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007678', 'descriptor_name': 'Kidney Glomerulus', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D007678', 'descriptor_name': 'Kidney Glomerulus', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 6, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/bf00422365', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/BF00422365.pdf', 'source': {'id': 'https://openalex.org/S104375418', 'display_name': 'Diabetologia', 'issn_l': '0012-186X', 'issn': ['0012-186X', '1432-0428'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/2066/21019', 'pdf_url': 'https://repository.ubn.ru.nl/bitstream/2066/21019/1/21019___.PDF', 'source': {'id': 'https://openalex.org/S4306401843', 'display_name': 'Data Archiving and Networked Services (DANS)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1322597698', 'host_organization_name': 'Royal Netherlands Academy of Arts and Sciences', 'host_organization_lineage': ['https://openalex.org/I1322597698'], 'host_organization_lineage_names': ['Royal Netherlands Academy of Arts and Sciences'], 'type': 'repository'}, 'license': 'other-oa', 'license_id': 'https://openalex.org/licenses/other-oa', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://hdl.handle.net/2066/144174', 'pdf_url': 'https://repository.ubn.ru.nl/bitstream/handle/2066/144174/1/144174.pdf', 'source': {'id': 'https://openalex.org/S4306401067', 'display_name': 'Radboud Repository (Radboud University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I145872427', 'host_organization_name': 'Radboud University Nijmegen', 'host_organization_lineage': ['https://openalex.org/I145872427'], 'host_organization_lineage_names': ['Radboud University Nijmegen'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/21019/21019___.PDF', 'pdf_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/21019/21019___.PDF', 'source': {'id': 'https://openalex.org/S4306401067', 'display_name': 'Radboud Repository (Radboud University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I145872427', 'host_organization_name': 'Radboud University Nijmegen', 'host_organization_lineage': ['https://openalex.org/I145872427'], 'host_organization_lineage_names': ['Radboud University Nijmegen'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/144174/144174.pdf', 'pdf_url': 'https://repository.ubn.ru.nl//bitstream/handle/2066/144174/144174.pdf', 'source': {'id': 'https://openalex.org/S4306401067', 'display_name': 'Radboud Repository (Radboud University)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I145872427', 'host_organization_name': 'Radboud University Nijmegen', 'host_organization_lineage': ['https://openalex.org/I145872427'], 'host_organization_lineage_names': ['Radboud University Nijmegen'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8690168', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1007/bf00422365', 'pdf_url': 'https://link.springer.com/content/pdf/10.1007/BF00422365.pdf', 'source': {'id': 'https://openalex.org/S104375418', 'display_name': 'Diabetologia', 'issn_l': '0012-186X', 'issn': ['0012-186X', '1432-0428'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 46, 'referenced_works': ['https://openalex.org/W1548081942', 'https://openalex.org/W1965642925', 'https://openalex.org/W1975370922', 'https://openalex.org/W1984011732', 'https://openalex.org/W1990986783', 'https://openalex.org/W1994310530', 'https://openalex.org/W1996393091', 'https://openalex.org/W2002837980', 'https://openalex.org/W2009015905', 'https://openalex.org/W2011520451', 'https://openalex.org/W2012678843', 'https://openalex.org/W2012706790', 'https://openalex.org/W2013044038', 'https://openalex.org/W2015875546', 'https://openalex.org/W2016319066', 'https://openalex.org/W2026840311', 'https://openalex.org/W2027003289', 'https://openalex.org/W2030385152', 'https://openalex.org/W2035907187', 'https://openalex.org/W2036657012', 'https://openalex.org/W2043286890', 'https://openalex.org/W2046303127', 'https://openalex.org/W2056631352', 'https://openalex.org/W2057704624', 'https://openalex.org/W206526553', 'https://openalex.org/W2066837348', 'https://openalex.org/W2067386856', 'https://openalex.org/W2069589041', 'https://openalex.org/W2073069882', 'https://openalex.org/W2077400092', 'https://openalex.org/W2079342336', 'https://openalex.org/W2083074809', 'https://openalex.org/W2086962905', 'https://openalex.org/W2093844592', 'https://openalex.org/W2106853316', 'https://openalex.org/W2111549736', 'https://openalex.org/W2132713923', 'https://openalex.org/W2135087475', 'https://openalex.org/W2135845349', 'https://openalex.org/W2150912407', 'https://openalex.org/W2306753853', 'https://openalex.org/W2324579467', 'https://openalex.org/W2343651967', 'https://openalex.org/W2420248158', 'https://openalex.org/W2464930416', 'https://openalex.org/W55539197'], 'related_works': ['https://openalex.org/W4248968658', 'https://openalex.org/W2396245893', 'https://openalex.org/W2137438657', 'https://openalex.org/W2122459695', 'https://openalex.org/W2099346887', 'https://openalex.org/W2083610249', 'https://openalex.org/W2048927510', 'https://openalex.org/W2040620718', 'https://openalex.org/W2026459492', 'https://openalex.org/W1970941411'], 'abstract_inverted_index': {'Heparan': [0], 'sulphate-associated': [1], 'anionic': [2, 81, 106, 176, 181, 186, 190, 216], 'sites': [3, 82, 107, 177, 187], 'in': [4, 11, 22, 84, 88, 124, 156, 193, 219, 241], 'the': [5, 29, 37, 52, 65, 94, 99, 111, 125, 130, 159, 168, 171, 179, 194, 199, 220, 224, 259, 264], 'glomerular': [6, 100, 131, 200, 225, 265], 'basement': [7, 101, 132, 201, 226, 266], 'membrane': [8, 133, 202, 227], 'were': [9, 91, 108, 119, 234], 'studied': [10], 'rats': [12, 144, 243], '8': [13, 154], 'months': [14, 155], 'after': [15, 153], 'induction': [16], 'of': [17, 51, 64, 80, 98, 105, 129, 173, 185, 198, 223, 263], 'diabetes': [18], 'by': [19, 58, 205, 209], 'streptozotocin': [20], 'and': [21, 24, 86, 114, 118, 135, 139, 178, 208, 214, 230], 'age-': [23], 'sex-matched': [25], 'control': [26, 89, 140, 160], 'rats,': [27, 141], 'employing': [28], 'cationic': [30], 'dye': [31], 'cuprolinic': [32, 53], 'blue.': [33], 'Morphometric': [34], 'analysis': [35], 'at': [36, 258], 'ultrastructural': [38], 'level': [39], 'was': [40, 56, 203], 'performed': [41], 'using': [42], 'a': [43, 250], 'computerized': [44], 'image': [45], 'processor.': [46], 'The': [47, 78], 'heparan': [48, 174, 252], 'sulphate': [49, 175, 253], 'specificity': [50], 'blue': [54], 'staining': [55], 'demonstrated': [57], 'glycosaminoglycan-degrading': [59], 'enzymes,': [60], 'showing': [61], 'that': [62, 240], 'pretreatment': [63], 'sections': [66], 'with': [67, 244], 'heparitinase': [68], 'abolished': [69], 'all': [70], 'staining,': [71], 'whereas': [72], 'chondroitinase': [73], 'ABC': [74], 'had': [75], 'no': [76], 'effect.': [77], 'majority': [79], '(74%': [83], 'diabetic': [85, 138], '81%': [87], 'rats)': [90], 'found': [92, 257], 'within': [93], 'lamina': [95, 112, 115, 126, 195, 231, 260], 'rara': [96, 116, 127, 196, 232, 261], 'externa': [97, 128, 197, 262], 'membrane.': [102, 267], 'A': [103], 'minority': [104], 'scattered': [109], 'throughout': [110], 'densa': [113, 229], 'interna,': [117], 'significantly': [120, 236], 'smaller': [121], 'than': [122], 'those': [123], '(p<0.001': [134], 'p<0.01': [136], 'for': [137], 'respectively).': [142], 'Diabetic': [143], 'progressively': [145], 'developed': [146], 'albuminuria': [147], 'reaching': [148], '40.3': [149], '(32.2–62.0)': [150], 'mg/24': [151, 164], 'h': [152], 'contrast': [157], 'to': [158], 'animals': [161], '(0.8': [162], '(0.2–0.9)': [163], 'h,': [165], 'p<0.002).': [166], 'At': [167], 'same': [169], 'time,': [170], 'number': [172], 'total': [180, 215], 'site': [182, 191, 217], 'surface': [183, 218], '(number': [184], '×': [188], 'mean': [189], 'surface)': [192], 'reduced': [204, 251], '19%': [206], '(p<0.021)': [207], '26%': [210], '(p<0.02),': [211], 'respectively.': [212], 'Number': [213], 'remaining': [221], 'part': [222], '(lamina': [228], 'interna)': [233], 'not': [235], 'changed.': [237], 'We': [238], 'conclude': [239], 'streptozotocin-diabetic': [242], 'an': [245], 'increased': [246], 'urinary': [247], 'albumin': [248], 'excretion,': [249], 'charge': [254], 'barrier/density': [255], 'is': [256]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2099346887', 'counts_by_year': [{'year': 2023, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-08-15T09:15:34.843013', 'created_date': '2016-06-24'}