Title: Retinopathy of prematurity in babies weighing <1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in Delhi
Abstract: International Journal of Medicine and Public Health,2014,4,4,359-363.DOI:10.4103/2230-8598.144066Published:Oct 2014Type:Original ArticleRetinopathy of prematurity in babies weighing <1800 g; with special reference to babies weighing between 1501 and 1800 g: An experience from a tertiary care hospital in DelhiRohit Kapoor, Richa Talwar, Soumya Sachdeva, Premila Paul, Rakesh Yadav, and Sarthak Sachdeva Rohit Kapoor, Richa Talwar1, Soumya Sachdeva2, Premila Paul3, Rakesh Yadav2, Sarthak Sachdeva4 GDMO I, CGHS Dispensary D56, Government of India, Krishna Nagar, 1Department of Community Medicine, Vardhman Mahavir Medical College and Safdarjung Hospital, 2Intern, Vardhman Mahavir Medical College and Safdarjung Hospital, 3Department of Pediatrics, Vardhman Mahavir Medical College and Safdarjung Hospital, Now In saket City Hospital, 4VMMC and SJH, GDMO II, 5Student, Maulana Azad Medical College, Bahadur shah zafar Marg, New Delhi, India Abstract:Background: Retinopathy of prematurity (ROP) is a disease related to low birth weight, prematurity, oxygen administration, and various other factors, which are yet to be identified. Aims: The aim was to find incidence of ROP and risk factors for causation in babies weighing <1800 g; and in the babies weighing between 1501 and 1800 g. Design: Prospective study. Materials and Methods: Neonates weighing ≤1800 g taking birth in our institution from January 2011 to January 2012 for a span of 1 year; were included in the study. The data were analyzed to determine risk factors for ROP causation. Information was collected using the standardized performa which included the maternal risk factors as well. Infants were classified by ophthalmologic examination findings using ICROP revisited. Statistics: Qualitative data were analyzed using Pearson's Chi-square test with Yates correction or Fisher's exact test and possible risk factors were analyzed by univariate analysis and multivariate analysis. Results: A total of 278 subjects was included in the study. Incidence of ROP in babies ≤1800 g was found to be 13.67% (38/278). Incidence of ROP in babies weighing between 1501 and 1800 g was 11.64% (17/146). Twenty-one risk factors were significant on univariate analysis in babies weighing ≤1800 g and 18 risk factors in the babies weighing between 1501 and 1800 g. Multiple gestations (P < 0.01), blood transfusion (P < 0.01), antepartum hemorrhage (P < 0.01), pregnancy-induced hypertension (P < 0.01), mechanical ventilation (MV) (P < 0.01), and APGAR at 1 min (P < 0.01) were found to be independently significant for ROP causation on logistic regression analysis in babies weighing ≤1800 g and MV (P < 0.01) and resuscitation (P < 0.01) were significant for babies weighing 1501-1800 g. Conclusion: It should be considered to incorporate screening of babies ≤1800 g uniformly in developing nations. It is recommended that further studies be done taking representative population of babies in different sites with adequate follow-up. Keywords:Birth weight, retinopathy of prematurity, risk factorsView:PDF (746.98 KB)
Publication Year: 2014
Publication Date: 2014-01-01
Language: en
Type: article
Indexed In: ['crossref']
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Cited By Count: 3
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