Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2097575874', 'doi': 'https://doi.org/10.1093/infdis/175.2.441', 'title': 'Inactivated Poliovirus Vaccine Protects Transgenic Poliovirus Receptor Mice against Type 3 Poliovirus Challenge', 'display_name': 'Inactivated Poliovirus Vaccine Protects Transgenic Poliovirus Receptor Mice against Type 3 Poliovirus Challenge', 'publication_year': 1997, 'publication_date': '1997-02-01', 'ids': {'openalex': 'https://openalex.org/W2097575874', 'doi': 'https://doi.org/10.1093/infdis/175.2.441', 'mag': '2097575874', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9203668'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/infdis/175.2.441', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/175/2/441/2440734/175-2-441.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/jid/article-pdf/175/2/441/2440734/175-2-441.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5025190549', 'display_name': 'Rolf E. Taffs', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1320320070', 'display_name': 'United States Food and Drug Administration', 'ror': 'https://ror.org/034xvzb47', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1320320070']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'R. E. Taffs', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland, USA.'], 'affiliations': [{'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland, USA.', 'institution_ids': ['https://openalex.org/I1320320070']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5073237703', 'display_name': 'Y. Chernokhvostova', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'Y. V. Chernokhvostova', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5109927273', 'display_name': 'E. Dragunsky', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'E. M. Dragunsky', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110361567', 'display_name': 'T Nomura', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'T. Nomura', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110156749', 'display_name': 'K Hioki', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'K. Hioki', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108474220', 'display_name': 'E. C. Beuvery', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'E. C. Beuvery', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5052669789', 'display_name': 'Edward A. Fitzgerald', 'orcid': 'https://orcid.org/0000-0002-0603-1241'}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'E. A. Fitzgerald', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062899446', 'display_name': 'Inessa S. Levenbook', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'I. S. Levenbook', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5109374951', 'display_name': 'David M. Asher', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210104433', 'display_name': 'National Institute for Public Health and the Environment', 'ror': 'https://ror.org/01cesdt21', 'country_code': 'NL', 'type': 'facility', 'lineage': ['https://openalex.org/I4210104433']}, {'id': 'https://openalex.org/I20783137', 'display_name': 'Central Institute for Experimental Animals', 'ror': 'https://ror.org/05eagc649', 'country_code': 'JP', 'type': 'facility', 'lineage': ['https://openalex.org/I20783137']}], 'countries': ['JP', 'NL'], 'is_corresponding': False, 'raw_author_name': 'D. M. Asher', 'raw_affiliation_strings': ['Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'Rockville, MD 20852-1448.'], 'affiliations': [{'raw_affiliation_string': 'Rijksinstituut voor Volksgezondheid en Milieuhygiene, Bilthoven, Netherlands', 'institution_ids': ['https://openalex.org/I4210104433']}, {'raw_affiliation_string': 'Rockville, MD 20852-1448.', 'institution_ids': []}, {'raw_affiliation_string': 'Food and Drug Administration, Rockville, Maryland; Central Institute for Experimental Animals, Kawasaki, Japan;', 'institution_ids': ['https://openalex.org/I20783137']}]}], 'institution_assertions': [], 'countries_distinct_count': 3, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4320, 'currency': 'USD', 'value_usd': 4320, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.666, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 11, 'citation_normalized_percentile': {'value': 0.678819, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 79, 'max': 80}, 'biblio': {'volume': '175', 'issue': '2', 'first_page': '441', 'last_page': '444'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11112', 'display_name': 'Viral Infections and Immunology Research', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/2705', 'display_name': 'Cardiology and Cardiovascular Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10976', 'display_name': 'Viral gastroenteritis research and epidemiology', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/2725', 'display_name': 'Infectious Diseases'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10613', 'display_name': 'Virus-based gene therapy research', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/inactivated-poliovirus-vaccine', 'display_name': 'Inactivated Poliovirus Vaccine', 'score': 0.8558321}], 'concepts': [{'id': 'https://openalex.org/C2779631682', 'wikidata': 'https://www.wikidata.org/wiki/Q12438936', 'display_name': 'Poliovirus', 'level': 3, 'score': 0.94184816}, {'id': 'https://openalex.org/C2908689829', 'wikidata': 'https://www.wikidata.org/wiki/Q1519099', 'display_name': 'Inactivated Poliovirus Vaccine', 'level': 4, 'score': 0.8558321}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.78613853}, {'id': 'https://openalex.org/C2779341262', 'wikidata': 'https://www.wikidata.org/wiki/Q182581', 'display_name': 'Immunity', 'level': 3, 'score': 0.7154065}, {'id': 'https://openalex.org/C2779261636', 'wikidata': 'https://www.wikidata.org/wiki/Q7003054', 'display_name': 'Neutralizing antibody', 'level': 3, 'score': 0.5528561}, {'id': 'https://openalex.org/C4870876', 'wikidata': 'https://www.wikidata.org/wiki/Q12195', 'display_name': 'Poliomyelitis', 'level': 2, 'score': 0.5481855}, {'id': 'https://openalex.org/C2780801004', 'wikidata': 'https://www.wikidata.org/wiki/Q1415366', 'display_name': 'Immunization', 'level': 3, 'score': 0.52758443}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.5238243}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.41539413}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4094802}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.37282336}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36830497}, {'id': 'https://openalex.org/C89423630', 'wikidata': 'https://www.wikidata.org/wiki/Q7193', 'display_name': 'Microbiology', 'level': 1, 'score': 0.34441006}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.33525905}], 'mesh': [{'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D011051', 'descriptor_name': 'Poliomyelitis', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D011051', 'descriptor_name': 'Poliomyelitis', 'qualifier_ui': 'Q000517', 'qualifier_name': 'prevention & control', 'is_major_topic': True}, {'descriptor_ui': 'D017955', 'descriptor_name': 'Poliovirus', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011054', 'descriptor_name': 'Poliovirus Vaccine, Inactivated', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D011991', 'descriptor_name': 'Receptors, Virus', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004306', 'descriptor_name': 'Dose-Response Relationship, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007116', 'descriptor_name': 'Immunization, Passive', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009500', 'descriptor_name': 'Neutralization Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011051', 'descriptor_name': 'Poliomyelitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011051', 'descriptor_name': 'Poliomyelitis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D017955', 'descriptor_name': 'Poliovirus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011054', 'descriptor_name': 'Poliovirus Vaccine, Inactivated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011054', 'descriptor_name': 'Poliovirus Vaccine, Inactivated', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D011991', 'descriptor_name': 'Receptors, Virus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015164', 'descriptor_name': 'Vaccines, Inactivated', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D015164', 'descriptor_name': 'Vaccines, Inactivated', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015164', 'descriptor_name': 'Vaccines, Inactivated', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/infdis/175.2.441', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/175/2/441/2440734/175-2-441.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9203668', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/infdis/175.2.441', 'pdf_url': 'https://academic.oup.com/jid/article-pdf/175/2/441/2440734/175-2-441.pdf', 'source': {'id': 'https://openalex.org/S54542293', 'display_name': 'The Journal of Infectious Diseases', 'issn_l': '0022-1899', 'issn': ['0022-1899', '1537-6613'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.81}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 16, 'referenced_works': ['https://openalex.org/W1575761699', 'https://openalex.org/W1965390534', 'https://openalex.org/W1991536902', 'https://openalex.org/W2010138215', 'https://openalex.org/W2012113393', 'https://openalex.org/W2027104244', 'https://openalex.org/W2027443345', 'https://openalex.org/W2029618072', 'https://openalex.org/W2052191300', 'https://openalex.org/W2067653920', 'https://openalex.org/W2091636904', 'https://openalex.org/W2106605115', 'https://openalex.org/W2126047127', 'https://openalex.org/W2135786757', 'https://openalex.org/W2468685310', 'https://openalex.org/W2914398215'], 'related_works': ['https://openalex.org/W982014063', 'https://openalex.org/W5567689', 'https://openalex.org/W3032447961', 'https://openalex.org/W2955357838', 'https://openalex.org/W2579288712', 'https://openalex.org/W2404169965', 'https://openalex.org/W2379966283', 'https://openalex.org/W1974313733', 'https://openalex.org/W1969304824', 'https://openalex.org/W1964807141'], 'abstract_inverted_index': {'Transgenic': [0], '(Tg)': [1], 'mice': [2], 'expressing': [3], 'the': [4], 'human': [5], 'poliovirus': [6, 13, 94, 109], 'receptor': [7], '(PVR)': [8], 'were': [9, 45, 54], 'vaccinated': [10], 'with': [11], 'inactivated': [12], 'vaccine': [14, 55], '(IPV)': [15], 'and': [16, 52, 127], 'evaluated': [17], 'for': [18, 47, 71, 128, 139], 'induced': [19], 'immunity': [20, 34], 'against': [21, 35, 99], 'type': [22, 29], '3': [23, 30], 'poliomyelitis.': [24], 'One': [25], 'injection': [26], 'of': [27, 42, 58, 133], 'monovalent': [28], 'IPV': [31, 44, 73, 89, 104, 124, 135], 'elicited': [32], 'protective': [33], 'wild-type': [36, 93, 100], 'poliovirus.': [37], 'In': [38], 'contrast,': [39], '2': [40], 'injections': [41], 'trivalent': [43, 134], 'required': [46], 'protection.': [48], 'Neutralizing': [49], 'antibody': [50, 68], 'response': [51], 'protection': [53, 84, 98], 'dose-dependent.': [56], 'Administration': [57], 'polio-immune': [59], 'mouse': [60], 'plasma': [61], 'protected': [62], 'unimmunized': [63], 'mice,': [64], 'demonstrating': [65], 'that': [66], 'neutralizing': [67], 'was': [69], 'sufficient': [70], 'immunity.': [72], 'heated': [74], 'to': [75, 130], 'remove': [76], 'its': [77], 'D': [78], 'antigen': [79], 'component': [80], 'did': [81], 'not': [82], 'induce': [83], 'in': [85, 121], 'Tg': [86, 114], 'PVR': [87, 115], 'mice.': [88], 'derived': [90, 105], 'from': [91, 106], 'a': [92], 'strain': [95], 'gave': [96], 'better': [97], 'viral': [101], 'challenge': [102], 'than': [103], 'an': [107], 'attenuated': [108], 'strain.': [110], 'The': [111], 'newly': [112], 'developed': [113], 'mouse-protection': [116], 'test': [117], 'may': [118], 'be': [119], 'useful': [120], 'evaluating': [122], 'existing': [123], 'potency': [125], 'tests': [126], 'attempts': [129], 'improve': [131], 'formulations': [132], 'or': [136], 'combined': [137], 'vaccines': [138], 'childhood': [140], 'immunization': [141], 'schedules.': [142]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2097575874', 'counts_by_year': [{'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-10T20:22:03.090705', 'created_date': '2016-06-24'}