Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2096817849', 'doi': 'https://doi.org/10.1002/rcm.985', 'title': 'Comparison of conventional and enhanced mass resolution triple‐quadrupole mass spectrometers for discovery bioanalytical applications', 'display_name': 'Comparison of conventional and enhanced mass resolution triple‐quadrupole mass spectrometers for discovery bioanalytical applications', 'publication_year': 2003, 'publication_date': '2003-03-06', 'ids': {'openalex': 'https://openalex.org/W2096817849', 'doi': 'https://doi.org/10.1002/rcm.985', 'mag': '2096817849', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12672138'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/rcm.985', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89689683', 'display_name': 'Rapid Communications in Mass Spectrometry', 'issn_l': '0951-4198', 'issn': ['0951-4198', '1097-0231'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5102942490', 'display_name': 'Xiao‐Ying Xu', 'orcid': 'https://orcid.org/0009-0004-3723-3032'}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Xiaoying Xu', 'raw_affiliation_strings': ['Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090993640', 'display_name': 'J. Veals', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John Veals', 'raw_affiliation_strings': ['Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5059164881', 'display_name': 'Walter A. Korfmacher', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Walter A. Korfmacher', 'raw_affiliation_strings': ['Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Drug Metabolism and Pharmacokinetics, Schering‐Plough Research Institute, Kenilworth, NJ 07033, USA.', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.007, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.633443, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '17', 'issue': '8', 'first_page': '832', 'last_page': '837'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10683', 'display_name': 'Mass Spectrometry Techniques and Applications', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10908', 'display_name': 'Analytical Chemistry and Chromatography', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T11423', 'display_name': 'Pesticide Residue Analysis and Safety', 'score': 0.999, 'subfield': {'id': 'https://openalex.org/subfields/1106', 'display_name': 'Food Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/hybrid-mass-spectrometer', 'display_name': 'Hybrid mass spectrometer', 'score': 0.73281085}, {'id': 'https://openalex.org/keywords/quadrupole-mass-analyzer', 'display_name': 'Quadrupole mass analyzer', 'score': 0.70403874}, {'id': 'https://openalex.org/keywords/bioanalysis', 'display_name': 'Bioanalysis', 'score': 0.54202724}, {'id': 'https://openalex.org/keywords/linearity', 'display_name': 'Linearity', 'score': 0.5242127}], 'concepts': [{'id': 'https://openalex.org/C172493649', 'wikidata': 'https://www.wikidata.org/wiki/Q7843529', 'display_name': 'Triple quadrupole mass spectrometer', 'level': 5, 'score': 0.90190184}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.86621106}, {'id': 'https://openalex.org/C162356407', 'wikidata': 'https://www.wikidata.org/wiki/Q180809', 'display_name': 'Mass spectrometry', 'level': 2, 'score': 0.83736646}, {'id': 'https://openalex.org/C710854', 'wikidata': 'https://www.wikidata.org/wiki/Q5953256', 'display_name': 'Hybrid mass spectrometer', 'level': 5, 'score': 0.73281085}, {'id': 'https://openalex.org/C103232671', 'wikidata': 'https://www.wikidata.org/wiki/Q874519', 'display_name': 'Quadrupole mass analyzer', 'level': 3, 'score': 0.70403874}, {'id': 'https://openalex.org/C138268822', 'wikidata': 'https://www.wikidata.org/wiki/Q1051925', 'display_name': 'Resolution (logic)', 'level': 2, 'score': 0.6402988}, {'id': 'https://openalex.org/C113196181', 'wikidata': 'https://www.wikidata.org/wiki/Q485223', 'display_name': 'Analytical Chemistry (journal)', 'level': 2, 'score': 0.6089881}, {'id': 'https://openalex.org/C71043704', 'wikidata': 'https://www.wikidata.org/wiki/Q17144692', 'display_name': 'Selected reaction monitoring', 'level': 4, 'score': 0.5860942}, {'id': 'https://openalex.org/C33390570', 'wikidata': 'https://www.wikidata.org/wiki/Q188463', 'display_name': 'Spectrometer', 'level': 2, 'score': 0.58556896}, {'id': 'https://openalex.org/C137535248', 'wikidata': 'https://www.wikidata.org/wiki/Q4914691', 'display_name': 'Bioanalysis', 'level': 2, 'score': 0.54202724}, {'id': 'https://openalex.org/C39984356', 'wikidata': 'https://www.wikidata.org/wiki/Q2121987', 'display_name': 'Quadrupole', 'level': 2, 'score': 0.5320284}, {'id': 'https://openalex.org/C77170095', 'wikidata': 'https://www.wikidata.org/wiki/Q1753188', 'display_name': 'Linearity', 'level': 2, 'score': 0.5242127}, {'id': 'https://openalex.org/C40684141', 'wikidata': 'https://www.wikidata.org/wiki/Q902061', 'display_name': 'Electrospray ionization', 'level': 3, 'score': 0.4929695}, {'id': 'https://openalex.org/C194451485', 'wikidata': 'https://www.wikidata.org/wiki/Q1327575', 'display_name': 'Electrospray', 'level': 3, 'score': 0.4757963}, {'id': 'https://openalex.org/C119128265', 'wikidata': 'https://www.wikidata.org/wiki/Q900165', 'display_name': 'Detection limit', 'level': 2, 'score': 0.42759395}, {'id': 'https://openalex.org/C87133666', 'wikidata': 'https://www.wikidata.org/wiki/Q1161699', 'display_name': 'Dynamic range', 'level': 2, 'score': 0.42183718}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.30105412}, {'id': 'https://openalex.org/C31827203', 'wikidata': 'https://www.wikidata.org/wiki/Q874296', 'display_name': 'Tandem mass spectrometry', 'level': 3, 'score': 0.28858048}, {'id': 'https://openalex.org/C120665830', 'wikidata': 'https://www.wikidata.org/wiki/Q14620', 'display_name': 'Optics', 'level': 1, 'score': 0.13389614}, {'id': 'https://openalex.org/C184779094', 'wikidata': 'https://www.wikidata.org/wiki/Q26383', 'display_name': 'Atomic physics', 'level': 1, 'score': 0.09512052}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.064487666}, {'id': 'https://openalex.org/C62520636', 'wikidata': 'https://www.wikidata.org/wiki/Q944', 'display_name': 'Quantum mechanics', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C154945302', 'wikidata': 'https://www.wikidata.org/wiki/Q11660', 'display_name': 'Artificial intelligence', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': 'Q000295', 'qualifier_name': 'instrumentation', 'is_major_topic': True}, {'descriptor_ui': 'D010949', 'descriptor_name': 'Plasma', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002138', 'descriptor_name': 'Calibration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013058', 'descriptor_name': 'Mass Spectrometry', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010949', 'descriptor_name': 'Plasma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012680', 'descriptor_name': 'Sensitivity and Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/rcm.985', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89689683', 'display_name': 'Rapid Communications in Mass Spectrometry', 'issn_l': '0951-4198', 'issn': ['0951-4198', '1097-0231'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12672138', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 15, 'referenced_works': ['https://openalex.org/W1562405229', 'https://openalex.org/W1964220924', 'https://openalex.org/W1983180957', 'https://openalex.org/W2006445428', 'https://openalex.org/W2008571018', 'https://openalex.org/W2027241935', 'https://openalex.org/W2042381797', 'https://openalex.org/W2062597092', 'https://openalex.org/W2063664884', 'https://openalex.org/W2091070913', 'https://openalex.org/W2110413022', 'https://openalex.org/W2161396059', 'https://openalex.org/W2209638', 'https://openalex.org/W2600005532', 'https://openalex.org/W4211236956'], 'related_works': ['https://openalex.org/W653058417', 'https://openalex.org/W3162908156', 'https://openalex.org/W2805718985', 'https://openalex.org/W2393067475', 'https://openalex.org/W2384134762', 'https://openalex.org/W2312747495', 'https://openalex.org/W2156009240', 'https://openalex.org/W2002235226', 'https://openalex.org/W1965187573', 'https://openalex.org/W1537459479'], 'abstract_inverted_index': {'Abstract': [0], 'A': [1], 'new': [2, 24, 91, 111, 147], 'triple‐quadrupole': [3, 52], 'mass': [4, 87, 92, 112, 117, 157], 'spectrometry': [5], '(MS)': [6], 'system': [7], 'with': [8, 47, 151], 'enhanced': [9, 116], 'resolution': [10, 88, 118], 'capabilities': [11], 'has': [12], 'recently': [13], 'become': [14], 'available.': [15], 'In': [16, 84], 'order': [17], 'to': [18, 96, 122, 141], 'evaluate': [19], 'the': [20, 31, 34, 41, 56, 81, 85, 90, 104, 110, 115, 132, 135, 146, 155], 'performance': [21], 'of': [22, 36, 49, 80, 109, 129], 'this': [23], 'instrument': [25, 53, 148], 'for': [26, 76, 145, 154], 'drug': [27], 'discovery': [28], 'assays,': [29], 'both': [30], 'linearity': [32], 'and': [33, 69], 'limit': [35], 'detection': [37], 'were': [38, 67], 'compared': [39, 150], 'in': [40], 'positive': [42], 'electrospray': [43], 'ionization': [44], '(ESI)': [45], 'mode': [46, 119], 'those': [48], 'a': [50, 77], 'conventional': [51, 105, 156], 'supplied': [54], 'by': [55, 71, 126], 'same': [57], 'manufacturer.': [58], 'For': [59, 131], 'these': [60], 'studies,': [61], 'spiked': [62], 'mouse': [63], 'plasma': [64], 'standard': [65], 'samples': [66], 'split': [68], 'assayed': [70], 'each': [72], 'instrument,': [73], 'which': [74], 'allowed': [75], 'direct': [78], 'comparison': [79], 'two': [82], 'systems.': [83], 'unit': [86], 'mode,': [89], 'spectrometer': [93, 113], 'was': [94, 120, 139], 'found': [95, 121, 140], 'be': [97, 123, 142], 'at': [98], 'least': [99], 'ten‐fold': [100], 'more': [101], 'sensitive': [102], 'than': [103], 'instrument.': [106], 'The': [107], 'sensitivity': [108], 'under': [114], 'even': [124], 'better': [125], 'another': [127], 'factor': [128], 'two.': [130], 'test': [133], 'compound,': [134], 'linear': [136], 'dynamic': [137], 'range': [138], '0.05–5000': [143], 'ng/mL': [144, 153], 'as': [149], '2.5–5000': [152], 'spectrometer.': [158], 'Copyright': [159], '©': [160], '2003': [161], 'John': [162], 'Wiley': [163], '&': [164], 'Sons,': [165], 'Ltd.': [166]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2096817849', 'counts_by_year': [{'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-15T13:02:41.662443', 'created_date': '2016-06-24'}