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[423], 'evidence': [426, 447], 'often': [430], 'prompted': [432], 'appearance': [435], 'vessel,': [438], 'not': [439, 967, 1046, 1228, 1266, 1321], 'symptoms': [443, 1077], 'ischemia.': [450], 'This': [451, 753, 971, 1067, 1127], 'phenomenon': [452], 'documented': [454], 'quite': [455], 'rigorously': [456], 'when': [457, 1155, 1253], 'patients': [458, 686, 828, 916, 964, 1017, 1037, 1071, 1090, 1200, 1436], 'randomized': [460, 684, 1424, 1638], 'receive': [462], 'protocol': [464, 475], 'angiogram–there': [466], 'flurry': [469], 'angiography': [476, 490, 997, 1378], 'group': [477, 743, 748, 769, 1053, 1062], 'subsequent': [478, 999], 'no': [482, 1295], 'seen': [486], 'group.1,2': [491], 'conclusion': [493], 'unmistakable–repeat': [495], 'subjective': [499, 1128, 1260], 'due': [504], 'vagaries': [508], 'physician': [510], 'choice': [511], 'than': [512, 744, 963, 1058, 1124], 'process.Despite': [516], 'clear': [518], 'limitations,': [519], 'become': [523, 659], 'favored': [525], 'serious': [533], 'death': [536], 'design': [548], 'with': [550, 687, 866, 981, 1021, 1158, 1311, 1437, 1555, 1622], 'sufficient': [551], 'statistical': [552], 'power': [553, 591], 'document': [555], 'reductions': [556], 'points.': [561], 'composite': [563, 635, 665, 715, 1270], 'major': [566, 636], 'adverse': [567, 637], 'cardiac': [568, 638], 'events': [569, 587, 639, 645], '(usually': [570], 'defined': [571], 'revascularization)': [578], 'devised': [580], 'increase': [582], 'number': [584], 'improve': [589], 'Composite': [595], 'general,': [600], 'composites': [602], 'include': [604], 'particularly': [608], 'problematic.3': [609], 'Having': [610], 'hardly': [616], 'bad': [618], 'having': [620], 'let': [624], 'alone': [625], 'dying,': [626], 'each': [628], 'same': [631], 'weight': [632], 'outcome.': [640, 1263], 'addition,': [642], 'vastly': [646], 'outnumber': [647], 'deaths': [649], 'infarctions': [652], 'any': [654], 'trial': [655, 806, 920, 1164], 'they': [658, 1081], 'primary': [661, 711, 734, 1271], 'driver': [662], 'point.The': [667], 'SYNTAX': [668, 673, 919, 1163], 'TrialThe': [669], '(Synergy': [674], 'Between': [675], 'With': [677], 'Taxus': [678], 'Cardiac': [680, 1916], 'Surgery)': [681], 'trial,': [682], 'which': [683, 1236], '1800': [685], '3-vessel': [688], 'left': [690], 'main': [691], 'heart': [693], 'artery': [697, 1513, 1618], 'bypass': [698, 1508, 1560, 1619, 1668], 'graft': [699], '(CABG)': [700], 'surgery': [701, 1620, 1669], 'drug-eluting': [706, 1427, 1556], 'stent,4': [707], 'chose': [708], 'stroke,': [721], '12': [727, 839, 858, 922, 961], 'months': [728, 840, 923, 962, 1035, 1380], 'following': [729], 'initial': [731], 'revascularization.': [732, 970, 1084], 'frequent': [739, 947], 'CABG': [742, 768, 831, 873, 1052, 1079, 1096, 1123, 1157, 1203, 1748, 1875], '(12.4%': [749], 'versus': [750, 771, 786, 853, 1506, 1670], '17.8%,': [751], 'P=0.002).': [752], 'result': [754], 'driven': [756], 'almost': [757, 783, 1210], 'lower': [761, 951], 'rate': [762], '(5.9%': [770], '13.5%,': [772], 'P<0.001)': [773], 'stroke': [781], 'identical': [784], '(7.7%': [785], '7.6%,': [787], 'P=0.98).': [788], 'collected': [792], 'information': [793], 'about': [794], 'disease-specific': [796, 910], 'general': [798, 912], 'participants': [803], 'Seattle': [809, 952], 'Questionnaire,': [811], 'Medical': [812, 1955], 'Outcomes': [813, 1871, 1910, 2111], 'Study': [814], '36-Item': [815], 'Short-Form': [816], 'Health': [817], 'Survey,': [818], 'European': [821], 'Life-5': [824], 'Dimensions': [825], 'instrument.5': [826], 'Overall,': [827], 'assigned': [829], 'significantly': [833], '6': [837, 959, 1034], 'follow-up,': [842], 'although': [843], 'absolute': [845], 'frequency': [849, 956, 1031], 'small': [851], '(76.3%': [852], '71.6%': [854], 'free': [856], 'months,': [859], 'P=0.05).': [860], 'These': [861], 'results': [862, 868], 'broadly': [864], 'consistent': [865], 'prior': [870], 'PCI.6In': [875], 'this': [876, 1005, 1318], 'issue': [877], 'Circulation:': [879, 2052], 'Outcomes,': [883, 2056], 'Arnold': [884, 1008, 1644], 'colleagues7': [886], 'status.': [897], 'They': [898], 'random-effects': [901], 'growth': [902], 'curve': [903], 'model': [904], 'define': [906], 'predictors': [908], 'among': [915, 1199, 1213], 'over': [921], 'follow-up.': [925], 'Despite': [926], 'relative': [928], 'short': [929], 'follow-up': [930, 944, 1422], 'period,': [931], 'longitudinal': [933], 'analysis': [934, 1006, 1631], 'provides': [935], 'several': [936], 'observations.Patients': [938], 'who': [939, 965, 1018, 1023, 1038, 1044, 1091], 'underwent': [940, 1082], 'during': [943], '(and,': [949], 'Questionnaire': [954], 'scores)': [957], 'did': [966, 1024, 1045], 'require': [968], 'finding': [972], 'what': [974], 'one': [975], 'would': [976], 'expect': [977], 'see:': [979], 'Patients': [980, 2047], 'greater': [982, 1049], 'residual': [983], 'recurrent': [985, 1093], 'experience': [987, 1074], 'likely': [993, 1099, 1110], 'undergo': [995], 'diagnostic': [996], 'revascularization.The': [1000], 'insight': [1003], 'colleagues': [1010], 'comes': [1011], 'from': [1012, 1161, 1288, 1636, 2144], 'comparing,': [1013], 'treatment': [1015, 1677], 'group,': [1016], 'required': [1019, 1039], 'those': [1022, 1043, 1323], 'not.': [1025], 'difference': [1027], 'score': [1032], 'between': [1036], 'substantially': [1048], '(mean': [1054, 1063], 'difference,': [1055, 1064], '19.8': [1056], 'points)': [1057], '8.5': [1065], 'points).': [1066], 'observation': [1068], 'suggests': [1069], 'severe': [1076, 1511], 'after': [1078, 1095, 1122, 1125, 1202, 1381, 1553, 1872], 'before': [1080], 'Although': [1085], 'possible': [1088], 'have': [1101], 'anatomy': [1102], 'amenable': [1103], 'revascularization,': [1106], 'physicians': [1112], 'simply': [1113], 'higher': [1116], 'threshold': [1117, 1192], 'recommending': [1119], 'PCI.': [1126], 'component,': [1129], 'differential': [1131], 'referral': [1132], 'pattern': [1133], 'based': [1136], 'preceding': [1139], 'procedure,': [1141], 'introduces': [1142], 'bias': [1144], 'use': [1147], 'comparing': [1156, 1254], 'PCI.ImplicationsThe': [1159], 'observations': [1160], 'underscore': [1165], 'limitations': [1167, 1460], 'response': [1184], 'symptoms,': [1186, 1241], 'angiogram,': [1188], 'performing': [1194], 'varies': [1198, 1212], '(higher': [1201], 'perhaps': [1205], 'older': [1207], 'patients)': [1208], 'certainly': [1211], 'physicians.': [1214], 'costly': [1218], 'inconvenient,': [1220], 'point,': [1225], 'does': [1227, 1265], 'treatment,': [1235], 'reduction': [1239], 'permanent': [1242], 'complications,': [1243], 'death.Although': [1245], 'extremely': [1250], 'relevant': [1251], 'consideration': [1252], 'strategies,': [1256], 'biased': [1262], 'It': [1264], 'belong': [1267], 'comparative': [1275], 'effectiveness': [1276], 'PCI.Sources': [1279], 'FundingThis': [1281], 'work': [1282], 'supported': [1284], 'grant': [1287], 'American': [1290, 1330, 1784, 1954, 2226], 'Heart': [1291, 1331, 2227], 'Association.DisclosuresDr': [1292], 'reports': [1294], 'conflicts.': [1296], 'Dr': [1297], 'served': [1300], 'consultant': [1303], 'Gilead': [1305], 'lists': [1307], 'all': [1308], 'his': [1309], 'relationships': [1310], 'industry': [1312], 'http://med.stanford.edu/profiles/Mark_Hlatky.FootnotesThe': [1314], 'opinions': [1315], 'expressed': [1316], 'article': [1319], 'necessarily': [1322], 'editors': [1326], 'Association.Correspondence': [1332], 'HRP': [1343], 'Redwood': [1344], 'Bldg,': [1345], 'Room': [1346], 'T150,': [1347], '259': [1348], 'Campus': [1349], 'Dr,': [1350], 'CA': [1352], '94305-5405.': [1353], 'E-mail': [1354], '[email': [1355], 'protected]eduReferences1.': [1356], 'Ruygrok': [1357], 'PN,': [1358], 'Melkert': [1359], 'R,': [1360, 1700, 1851, 1857, 1968, 1976, 1980, 1986, 2008], 'Morel': [1361], 'MAM,': [1362], 'Ormiston': [1363, 1404], 'JA,': [1364, 1405], 'Bär': [1365], 'FW,': [1366, 1530, 1655], 'Fernandez-Avilès': [1367], 'F,': [1368, 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[2009], 'Popp': [2011], 'Ordóñez-Llanos': [2013], 'Santalo-Bel': [2015], 'Horner': [2017], 'Dolci': [2019], 'Jernberg': [2021], 'Zaninotto': [2023], 'Manara': [2025], 'Dinkel': [2027], 'Menassanch-Volker': [2029], 'Jarausch': [2031], 'Zaugg': [2034], 'Prognostic': [2037], 'Utility': [2038, 2162], 'Modified': [2041], 'HEART': [2042], 'Score': [2043], 'Chest': [2045], 'Pain': [2046], 'Emergency': [2050], 'Department,': [2051], '10:2,': [2057], '1-Feb-2017.': [2061], 'Carnero-Alcázar': [2062], 'M': [2063], 'Villagrán-Medinilla': [2065], 'Nuestra': [2068], 'verdad': [2069], 'sobre': [2070], 'SYNTAX,': [2071], 'Cirugía': [2072], 'Cardiovascular,': [2073], '10.1016/j.circv.2016.11.003,': [2074], '24:1,': [2075], '(26-32),': [2076], '1-Jan-2017.': [2080], 'Parasca': [2081], 'Head': [2083], 'Milojevic': [2085], 'D': [2102], '(2016)': [2106], 'Incidence,': [2107], 'Characteristics,': [2108], 'Predictors,': [2109], 'Intervention': [2118], 'Artery': [2121], 'Bypass': [2122], 'Grafting,': [2123], 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