Title: Use of Theraflex-TMJ Topical Cream for the Treatment of Temporomandibular Joint and Muscle Pain
Abstract: AbstractAbstractThis randomized, double-blind study was designed to evaluate the effectiveness of the topical cream Theraflex-TMJ (NaBob/Rx, San Mateo, CA) in patients with masseter muscle pain and temporomandibular joint (TMJ) pain. Fifty-two subjects (5 males and 47 females) were instructed to apply a cream over the afflicted masseter muscle(s) or over the jaw joint(s) twice daily for two weeks. Theraflex-TMJ cream was used by the experimental group, while a placebo cream was used by the control group. The means of pain ratings were calculated prior to the application of the cream (baseline), after ten days of tx (period 1), and 15 days of tx (period 2) days of treatment and five days after stopping the treatment (follow-up). There was a significant decrease in reported pain levels from baseline in the experimental group for period 1 (p<0.01), period 2 (p<0.001), and follow-up (p<0.01). For the control group, no significant differences were found between the different time periods (p>0.05). There was evidence of minor side effects such as skin irritation and/or burning on the site of the application in two subjects in the experimental as well as two subjects in the control groups. The data strongly suggest that Theraflex-TMJ topical cream is safe and effective for reducing pain in the masseter muscle and the temporomandibular joint. Additional informationNotes on contributorsSilvia Lobo LoboDr. Silvia Lobo Lobo received her D.D.S. degree at Universidad Latinoamericana de Ciencia y Tecnologia, San Jose, Costa Rica in 1999. In 2002, she completed the TMD and Orofacial Pain program at the Craniofacial Pain Center at Tufts University School of Dental Medicine. She received a M.S. degree from Tufts University School, Boston, Massachusetts in 2002. Dr. Lobo Lobo is working as an assistant professor at the Craniofacial Pain Center and has published several scientific papers.Noshir MehtaDr. Noshir R. Mehta is Professor and Chairman of General Dentistry and Director of the Craniofacial Pain Center at Tufts University School of Dental Medicine, Boston, Massachusetts. He holds a Diplomate from the American Board of Orofacial Pain and is a Fellow of the International College of Dentists. Since receiving his D.M.D. degree and his M.S. in Periodontics at Tufts University, he has been involved in occlusion research. Dr. Mehta has lectured internationally on TMD/MPD and has published numerous scientific papers.Albert G. ForgioneDr. Albert Forgione is the Chief Consultant of Craniofacial Pain Center at Tufts University School of Dental Medicine, Boston, Massachusetts. He received a Ph.D. in psychology from Boston University and then joined Tufts University and lectured in Behavioral Medicine. Dr. Forgione established the TMJ center at Tufts University School of Dental Medicine with Dr. Mehta in 1978.Marcello MelisDr. Marcello Melis received his degree in Pharmacy from the University of Cagliari (Italy) in 1990, and his D.M.D. from the Dental School of the same university in 1998. He was a resident in the Gelb Orofacial Pain Center at Tufts University, Boston (U.S.A.) from 1998 to 2000. Currently he practices in Cagliari in the field of TMD and orofacial pain, and he has been involved in several international research activities focusing on TMD and orofacial pain, occlusion, and muscle function.Emad Al-BadawiDr. Emad A. Al-Badawi received his B.D.S. degree at the King Abdulaziz University Faculty of Dentistry in Jeddah, Saudi Arabia in 1995. He spent the next three years as an oral surgery resident at King Fahad Hospital, Jeddah, Saudi Arabia. In 1998 he joined the TMD and Orofacial Pain Program at the Craniofacial Pain Center at Tufts University School of Dental Medicine, Boston, Massachusetts and was awarded an M.S. degree in 2001. Currently, Dr. Al-Badawi is a senior resident at the Pediatric Dentistry Department at Tufts University School of Dental Medicine.Caroline CenevizDr. Caroline Ceneviz received her dental degree from UNIARARAS in Sao Paulo, Brazil in 2001. She completed her fellowship in TMD and orofacial pain in 2003 at Tufts University School of Dental Medicine, Boston, Massachusetts. She is currently pursuing her Master's degree at the same institution.Khalid H. ZawawiDr. Kahid Zawawi received his B.D.S. at Pumjab University, De'Montmorency College of Dentistry, Pakistan in 1992. He spent six years as a clinical instructor in the Department of Oral Surgery at King Abdulaziz University, Faculty of Dentistry in Jeddah, Saudi Arabia. In 2001, he completed the certification program in TMD and orofacial pain at the Craniofacial Pain Center at Tufts University School of Dental Medicine, Boston, Massachusetts. Dr. Zawawi is currently at research associate at the Gelb Center and is working on a Doctor of Science degree in oral biology at the Boston University School of Dental Medcine.
Publication Year: 2004
Publication Date: 2004-04-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 33
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