Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2095529697', 'doi': 'https://doi.org/10.1002/syn.890140409', 'title': 'Alterations in the dopaminergic receptor system after chronic administration of cocaine', 'display_name': 'Alterations in the dopaminergic receptor system after chronic administration of cocaine', 'publication_year': 1993, 'publication_date': '1993-08-01', 'ids': {'openalex': 'https://openalex.org/W2095529697', 'doi': 'https://doi.org/10.1002/syn.890140409', 'mag': '2095529697', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8161369'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/syn.890140409', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S158211696', 'display_name': 'Synapse', 'issn_l': '0887-4476', 'issn': ['0887-4476', '1098-2396'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109812923', 'display_name': 'Mario E. Alburges', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57328836', 'display_name': 'North Dakota State University', 'ror': 'https://ror.org/05h1bnb22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57328836']}, {'id': 'https://openalex.org/I24571045', 'display_name': 'University of North Dakota', 'ror': 'https://ror.org/04a5szx83', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I24571045']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Mario E. Alburges', 'raw_affiliation_strings': ['Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105', 'Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105', 'institution_ids': ['https://openalex.org/I57328836']}, {'raw_affiliation_string': 'Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202', 'institution_ids': ['https://openalex.org/I24571045']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041977361', 'display_name': 'Neelam Narang', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I57328836', 'display_name': 'North Dakota State University', 'ror': 'https://ror.org/05h1bnb22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57328836']}, {'id': 'https://openalex.org/I24571045', 'display_name': 'University of North Dakota', 'ror': 'https://ror.org/04a5szx83', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I24571045']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Neelam Narang', 'raw_affiliation_strings': ['Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105', 'Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202'], 'affiliations': [{'raw_affiliation_string': 'Department of Pharmaceutical Sciences, North Dakota State University, Fargo, North Dakota 58105', 'institution_ids': ['https://openalex.org/I57328836']}, {'raw_affiliation_string': 'Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202', 'institution_ids': ['https://openalex.org/I24571045']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111822762', 'display_name': 'James K. Wamsley', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I24571045', 'display_name': 'University of North Dakota', 'ror': 'https://ror.org/04a5szx83', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I24571045']}, {'id': 'https://openalex.org/I57328836', 'display_name': 'North Dakota State University', 'ror': 'https://ror.org/05h1bnb22', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I57328836']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'James K. Wamsley', 'raw_affiliation_strings': ['Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202', 'Professor, Department of Pharmaceutical Sciences, College of Pharmacy, Sudro Hall, North Dakota State University, Fargo, ND 58105'], 'affiliations': [{'raw_affiliation_string': 'Departments of Pharmacology and Neuroscience, University of North Dakota, Grand Forks, North Dakota 58202', 'institution_ids': ['https://openalex.org/I24571045']}, {'raw_affiliation_string': 'Professor, Department of Pharmaceutical Sciences, College of Pharmacy, Sudro Hall, North Dakota State University, Fargo, ND 58105', 'institution_ids': ['https://openalex.org/I57328836']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3240, 'currency': 'USD', 'value_usd': 3240, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 2.258, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 80, 'citation_normalized_percentile': {'value': 0.862361, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '14', 'issue': '4', 'first_page': '314', 'last_page': '323'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10056', 'display_name': 'Neurotransmitter Receptor Influence on Behavior', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9983, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/raclopride', 'display_name': 'Raclopride', 'score': 0.91121495}, {'id': 'https://openalex.org/keywords/dopamine-uptake-inhibitors', 'display_name': 'Dopamine Uptake Inhibitors', 'score': 0.5563678}], 'concepts': [{'id': 'https://openalex.org/C2781069445', 'wikidata': 'https://www.wikidata.org/wiki/Q7279814', 'display_name': 'Raclopride', 'level': 4, 'score': 0.91121495}, {'id': 'https://openalex.org/C513476851', 'wikidata': 'https://www.wikidata.org/wiki/Q170304', 'display_name': 'Dopamine', 'level': 2, 'score': 0.7645683}, {'id': 'https://openalex.org/C137183658', 'wikidata': 'https://www.wikidata.org/wiki/Q461076', 'display_name': 'Dopaminergic', 'level': 3, 'score': 0.71100354}, {'id': 'https://openalex.org/C2780062018', 'wikidata': 'https://www.wikidata.org/wiki/Q1319792', 'display_name': 'Striatum', 'level': 3, 'score': 0.6503352}, {'id': 'https://openalex.org/C2776219046', 'wikidata': 'https://www.wikidata.org/wiki/Q162657', 'display_name': 'Neurotransmitter', 'level': 3, 'score': 0.59475493}, {'id': 'https://openalex.org/C2908949072', 'wikidata': 'https://www.wikidata.org/wiki/Q899647', 'display_name': 'Dopamine Uptake Inhibitors', 'level': 4, 'score': 0.5563678}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5338296}, {'id': 'https://openalex.org/C120069818', 'wikidata': 'https://www.wikidata.org/wiki/Q415496', 'display_name': 'Dopamine receptor', 'level': 3, 'score': 0.5250071}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.5225936}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.50411046}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.48924398}, {'id': 'https://openalex.org/C44208683', 'wikidata': 'https://www.wikidata.org/wiki/Q15335165', 'display_name': 'Dopamine receptor D2', 'level': 3, 'score': 0.46690613}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.4356783}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.32348946}, {'id': 'https://openalex.org/C15744967', 'wikidata': 'https://www.wikidata.org/wiki/Q9418', 'display_name': 'Psychology', 'level': 0, 'score': 0.22108337}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.21430051}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.19130895}], 'mesh': [{'descriptor_ui': 'D001923', 'descriptor_name': 'Brain Chemistry', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D003042', 'descriptor_name': 'Cocaine', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D011954', 'descriptor_name': 'Receptors, Dopamine', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001552', 'descriptor_name': 'Benzazepines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D001552', 'descriptor_name': 'Benzazepines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001552', 'descriptor_name': 'Benzazepines', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D001923', 'descriptor_name': 'Brain Chemistry', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002540', 'descriptor_name': 'Cerebral Cortex', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003042', 'descriptor_name': 'Cocaine', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D003042', 'descriptor_name': 'Cocaine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003342', 'descriptor_name': 'Corpus Striatum', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D003342', 'descriptor_name': 'Corpus Striatum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003342', 'descriptor_name': 'Corpus Striatum', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D004298', 'descriptor_name': 'Dopamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010622', 'descriptor_name': 'Phencyclidine', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D010622', 'descriptor_name': 'Phencyclidine', 'qualifier_ui': 'Q000031', 'qualifier_name': 'analogs & derivatives', 'is_major_topic': False}, {'descriptor_ui': 'D010622', 'descriptor_name': 'Phencyclidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020891', 'descriptor_name': 'Raclopride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011954', 'descriptor_name': 'Receptors, Dopamine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017447', 'descriptor_name': 'Receptors, Dopamine D1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017447', 'descriptor_name': 'Receptors, Dopamine D1', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D017447', 'descriptor_name': 'Receptors, Dopamine D1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017448', 'descriptor_name': 'Receptors, Dopamine D2', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D017448', 'descriptor_name': 'Receptors, Dopamine D2', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D017448', 'descriptor_name': 'Receptors, Dopamine D2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012457', 'descriptor_name': 'Salicylamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012457', 'descriptor_name': 'Salicylamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D012457', 'descriptor_name': 'Salicylamides', 'qualifier_ui': 'Q000493', 'qualifier_name': 'pharmacokinetics', 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/syn.890140409', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S158211696', 'display_name': 'Synapse', 'issn_l': '0887-4476', 'issn': ['0887-4476', '1098-2396'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8161369', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.85, 'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 62, 'referenced_works': ['https://openalex.org/W1503918021', 'https://openalex.org/W1875134538', 'https://openalex.org/W1924151174', 'https://openalex.org/W1935648224', 'https://openalex.org/W1958508926', 'https://openalex.org/W1966092598', 'https://openalex.org/W1971248803', 'https://openalex.org/W1991442236', 'https://openalex.org/W1994024775', 'https://openalex.org/W1995215146', 'https://openalex.org/W1998128937', 'https://openalex.org/W1998863061', 'https://openalex.org/W2001885697', 'https://openalex.org/W2005239439', 'https://openalex.org/W2007604257', 'https://openalex.org/W2007689138', 'https://openalex.org/W2014467836', 'https://openalex.org/W2016732346', 'https://openalex.org/W2040172438', 'https://openalex.org/W2043881516', 'https://openalex.org/W2046041603', 'https://openalex.org/W2059230444', 'https://openalex.org/W2061418383', 'https://openalex.org/W2061552082', 'https://openalex.org/W2062608310', 'https://openalex.org/W2062849160', 'https://openalex.org/W2065027511', 'https://openalex.org/W2071763279', 'https://openalex.org/W2075584859', 'https://openalex.org/W2077153133', 'https://openalex.org/W2077760177', 'https://openalex.org/W2080107751', 'https://openalex.org/W2083129185', 'https://openalex.org/W2087978136', 'https://openalex.org/W2088840746', 'https://openalex.org/W2095217951', 'https://openalex.org/W2110845857', 'https://openalex.org/W2116220859', 'https://openalex.org/W2128635872', 'https://openalex.org/W2146835230', 'https://openalex.org/W2165398609', 'https://openalex.org/W2165629378', 'https://openalex.org/W2172219495', 'https://openalex.org/W222718589', 'https://openalex.org/W2238091929', 'https://openalex.org/W2266384016', 'https://openalex.org/W2272402201', 'https://openalex.org/W2330759546', 'https://openalex.org/W2337318114', 'https://openalex.org/W2400676841', 'https://openalex.org/W2405885484', 'https://openalex.org/W2408985440', 'https://openalex.org/W2411479955', 'https://openalex.org/W2415565555', 'https://openalex.org/W2418284846', 'https://openalex.org/W2463165598', 'https://openalex.org/W2765848309', 'https://openalex.org/W4239671216', 'https://openalex.org/W4293247451', 'https://openalex.org/W563941073', 'https://openalex.org/W586370793', 'https://openalex.org/W617032755'], 'related_works': ['https://openalex.org/W4231250939', 'https://openalex.org/W2969587200', 'https://openalex.org/W2752517690', 'https://openalex.org/W2748692383', 'https://openalex.org/W2133285326', 'https://openalex.org/W2073811833', 'https://openalex.org/W2043116924', 'https://openalex.org/W2015145997', 'https://openalex.org/W1993691356', 'https://openalex.org/W1963961674'], 'abstract_inverted_index': {'Abstract': [0], 'Several': [1], 'studies': [2], 'suggest': [3], 'that': [4, 178], 'one': [5], 'of': [6, 21, 35, 39, 43, 52, 61, 110, 125, 243], 'the': [7, 19, 22, 26, 36, 81, 95, 98, 167, 244], 'most': [8], 'important': [9], 'factors': [10], 'contributing': [11], 'to': [12, 32, 57, 86, 114, 135, 159, 181], 'cocaine': [13, 40, 48, 126, 182], 'dependence': [14], 'is': [15], 'an': [16, 184, 208], 'alteration': [17], 'in': [18, 25, 75, 97, 147, 169, 188, 199, 210, 222], 'actions': [20], 'neurotransmitter': [23], 'dopamine': [24, 117, 136, 162, 245], 'central': [27], 'nervous': [28], 'system.': [29, 246], 'In': [30, 128], 'order': [31], 'understand': [33], 'some': [34], 'neuroreceptor': [37], 'consequences': [38], 'administration,': [41], 'groups': [42], 'rats': [44], 'were': [45], 'injected': [46], 'with': [47, 207], '(2': [49], 'daily': [50], 'doses': [51], '15': [53], 'mg/kg)': [54], 'for': [55], '1': [56, 116, 191, 213], '21': [58], 'days.': [59], 'Binding': [60], '[': [62, 65, 68, 72, 88, 111, 131, 155], '3': [63, 66, 69, 73, 89, 112, 124, 132, 156], 'H]cocaine,': [64], 'H]SCH23390,': [67], 'H]raclopride,': [70], 'and': [71, 77, 100, 105, 172, 194, 216], 'H]BTCP': [74, 133], 'striatal': [76, 129, 173, 211], 'cortical': [78, 148, 171, 189], 'tissue': [79], 'from': [80, 152], 'treated': [82], 'animals': [83], 'was': [84, 92, 119, 139, 150], 'compared': [85], 'controls.': [87], 'H]Cocaine': [90], 'binding': [91, 109, 134, 146, 158], 'increased': [93, 121, 141, 151], 'by': [94], 'drug': [96], 'striatum': [99], 'cortex': [101], 'at': [102, 122], 'days': [103], '14': [104], '21,': [106], 'respectively.': [107], 'The': [108], 'H]SCH23390': [113], 'D': [115, 160, 190, 212, 223], 'receptors': [118, 163], 'significantly': [120, 140], 'day': [123, 143, 153], 'exposure.': [127], 'membranes,': [130], 'uptake': [137], 'sites': [138, 196], 'after': [142], '7,': [144], 'whereas': [145], 'membranes': [149], '1.': [154], 'H]Raclopride': [157], '2': [161, 224], 'remained': [164], 'unchanged': [165], 'throughout': [166], 'study': [168], 'both': [170], 'tissues.': [174], 'These': [175, 203], 'results': [176], 'indicate': [177], 'repeated': [179], 'exposure': [180], 'produces': [183], 'upregulation': [185, 209], '(possible': [186], 'supersensitivity)': [187], ',': [192, 214], 'cocaine,': [193, 215], 'DA‐uptake': [195, 217], 'which': [197], 'occurs': [198], 'a': [200], 'time‐dependent': [201], 'manner.': [202], 'increases': [204], 'are': [205, 229, 239], 'coupled': [206], 'sites,': [218], 'without': [219], 'simultaneous': [220], 'changes': [221], 'receptors.': [225], 'Thus,': [226], "cocaine's": [227], 'effects': [228], 'not': [230], 'uniformly': [231], 'distributed': [232], 'across': [233], 'all': [234], 'brain': [235], 'regions,': [236], 'but': [237], 'rather': [238], 'focused': [240], 'within': [241], 'areas': [242], '©': [247], '1993': [248], 'Wiley‐Liss,': [249], 'Inc.': [250]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2095529697', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}], 'updated_date': '2024-12-10T01:24:28.162421', 'created_date': '2016-06-24'}