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396, 447, 494, 526, 536, 551, 556, 576, 593, 610, 621, 629, 635, 672, 696, 720, 729, 772, 775, 782, 796, 810, 832, 903, 919, 921, 979, 984, 990, 995, 1031, 1038, 1065, 1078, 1144, 1187, 1215, 1263, 1340, 1397, 1403, 1412, 1416, 1485, 1510, 1555, 1578, 1580, 1616, 1700, 1707, 1713, 1818, 1826, 1858, 1869, 1961, 1969, 1975, 2000, 2074, 2126, 2180, 2246, 2249, 2255], 'Acute': [5, 38, 516], 'Inflammatory': [6, 39], 'Myocarditis': [7, 40, 2257], 'in': [8, 41, 452, 523, 604, 613, 663, 711, 769, 830, 853, 880, 897, 913, 954, 961, 1088, 1195, 1218, 1258, 1309, 1334, 1375, 1382, 1455, 1490, 1515, 1666, 1704, 1739, 1744, 1860, 2123, 2146, 2163, 2183, 2192, 2218, 2252], 'Epstein': [9, 42, 438, 448, 464], 'Barr': [10, 43, 439, 449, 465], 'Virus': [11, 44, 440, 450, 466], 'Infection': [12, 45, 1335, 1579, 1740], 'Using': [13, 46, 907], 'Hybrid': [14, 47, 1292, 1315, 1556, 1805, 1948, 1976], '18F-Fluoro-Deoxyglucose–Positron': [15, 48], 'Emission': [16, 49, 1600], 'Tomography/Magnetic': [17, 50, 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986, 1094, 1151, 1189, 1198, 1253, 1266, 1286, 1304, 1312, 1323, 1331, 1336, 1360, 1369, 1391, 1410, 1442, 1451, 1479, 1504, 1513, 1522, 1546, 1571, 1594, 1611, 1636, 1643, 1651, 1660, 1694, 1734, 1741, 1801, 1822, 1853, 1883, 1892, 1944, 1965, 1994, 2020, 2028, 2042, 2086, 2114, 2140, 2174, 2189, 2206, 2212, 2240], 'Tareq': [70, 300], 'Ibrahim,': [71], 'OlshausenGesa': [75], 'Olshausen': [77, 1093], 'From': [78, 123, 168, 213, 258, 303], 'the': [79, 124, 169, 214, 259, 304, 393, 397, 415, 453, 471, 497, 524, 537, 577, 597, 605, 622, 627, 633, 664, 670, 712, 727, 750, 755, 770, 776, 783, 794, 808, 901, 916, 922, 975, 982, 987, 993, 1029, 1036, 1063, 1070, 1213, 1224, 1413, 1581, 1705, 1815, 1823, 1958, 1966, 2124, 2247, 2253], 'Medizinische': [80, 125, 170, 215, 260, 305, 1107], 'Klinik': [81, 90, 126, 135, 171, 180, 216, 225, 261, 270, 306, 315], 'und': [82, 91, 127, 136, 172, 181, 217, 226, 262, 271, 307, 316], 'Poliklinik': [83, 92, 128, 137, 173, 182, 218, 227, 263, 272, 308, 317], '(G.v.O.,': [84, 129, 174, 219, 264, 309], 'N.L.,': [85, 130, 175, 220, 265, 310], 'K.-L.L.,': [86, 131, 176, 221, 266, 311], 'T.I.)': [87, 132, 177, 222, 267, 312], 'Nuklearmedizinische': [89, 134, 179, 224, 269, 314], '(F.H.,': [93, 138, 183, 228, 273, 318], 'M.S.),': [94, 139, 184, 229, 274, 319], 'Klinikum': [95, 140, 185, 230, 275, 320], 'rechts': [96, 141, 186, 231, 276, 321], 'der': [97, 142, 187, 232, 277, 322], 'Isar,': [98, 143, 188, 233, 278, 323], 'Technische': [99, 144, 189, 234, 279, 324, 1109], 'Universität': [100, 145, 190, 235, 280, 325, 1110], 'München,': [101, 146, 191, 236, 281, 326, 1111, 1115], 'Munich,': [102, 116, 147, 161, 192, 206, 237, 251, 282, 296, 327, 341], 'Germany;': [103, 148, 193, 238, 283, 328], 'DZHK': [105, 150, 195, 240, 285, 330], '(German': [106, 151, 196, 241, 286, 331], 'Centre': [107, 152, 197, 242, 287, 332], 'for': [108, 153, 198, 243, 288, 333, 793, 981, 992, 1041, 1048, 1062, 1072, 1645, 2052, 2121, 2215], 'Cardiovascular': [109, 154, 199, 244, 289, 334, 1140, 1310, 1603, 1667, 1819, 1962, 2024, 2031, 2056, 2068, 2090, 2096, 2184, 2193], 'Research),': [110, 155, 200, 245, 290, 335], 'Partner': [111, 156, 201, 246, 291, 336], 'Site': [112, 157, 202, 247, 292, 337], 'Munich': [113, 158, 203, 248, 293, 338], 'Heart': [114, 159, 204, 249, 294, 339, 1227, 2147, 2281], 'Alliance,': [115, 160, 205, 250, 295, 340], 'Germany': [117, 162, 207, 252, 297, 342], '(K.-L.L.).': [118, 163, 208, 253, 298, 343], ',': [119, 164, 209, 254], 'HyafilFabien': [121], 'Hyafil': [122, 1095, 2105], 'LangwieserNicolas': [166], 'Langwieser': [167], 'LaugwitzKarl-Ludwig': [211], 'Laugwitz': [212], 'SchwaigerMarkus': [256], 'Schwaiger': [257, 2115], 'IbrahimTareq': [301], 'Ibrahim': [302], 'Originally': [344, 2285], 'published9': [345], 'Sep': [346], '2014https://doi.org/10.1161/CIRCULATIONAHA.114.011000Circulation.': [347], '2014;130:925–926IntroductionA': [348], '21-year-old': [349], 'man': [350], 'with': [351, 400, 542, 581, 661, 715, 732, 741, 761, 855, 882, 963, 1000, 1004, 1013, 1220, 1260, 1400, 1405, 1518, 2220, 2258], 'persistent': [352], 'retrosternal': [353], 'chest': [354], 'pain': [355], 'was': [356, 417, 443, 468, 473, 518, 800, 934], 'admitted': [357], 'our': [359, 914], 'institution.': [360], 'Diffuse': [361], 'repolarization': [362], 'abnormalities': [363], 'were': [364], 'present': [365], 'on': [366, 520, 562, 639, 682, 836, 1212, 1649, 2262], 'initial': [367], 'ECG.': [368], 'Laboratory': [369], 'testing': [370], 'detected': [371, 660, 710], 'elevated': [372], 'cardiac': [373, 521, 721, 787, 837, 848, 861, 966, 1708, 1806, 1949], 'enzymes': [374], '(troponin': [375], 'T': [376, 1596, 1855, 2066, 2173, 2176], '3,14ng/mL,': [377], 'creatine': [378, 382], 'kinase': [379, 383], '1275': [380], 'U/I,': [381], 'myocardial': [384, 492, 1261, 2221], 'band': [385], 'fraction': [386], '77': [387], 'U/l).': [388], 'Echocardiography': [389], 'identified': [390, 586], 'hypokinesia': [391], 'anterolateral': [394], 'wall': [395, 539, 579, 607, 666, 714], 'left': [398, 777, 1188, 1255, 1267], 'ventricle': [399], 'impaired': [401], 'systolic': [402], 'function.': [403], 'Subsequent': [404], 'coronary': [405, 408], 'angiography': [406], 'excluded': [407], 'artery': [409], 'disease.': [410], 'On': [411], 'further': [412], 'physical': [413], 'examination,': [414], 'patient': [416, 472, 498, 1399], 'found': [418, 801], 'be': [420, 585, 659, 709, 759, 822, 851, 925, 959, 1022, 1057, 1086], 'febrile': [421], 'had': [423, 499], 'palpable': [424], 'generalized': [425], 'lymphadenopathy': [426], 'as': [427, 429, 530, 532, 570, 572, 648, 650, 688, 690, 860, 887, 911], 'well': [428, 531, 571, 649, 689], 'splenomegaly.': [430], 'Among': [431], 'other': [432], 'possibilities,': [433], 'we': [434], 'suspected': [435, 469, 742, 1001], 'a': [436, 476, 502, 566, 685, 908, 1005, 1147, 1398, 1810, 1953, 2259], 'primary': [437], 'infection,': [441, 1520], 'which': [442], 'confirmed': [444, 519, 626], 'by': [445, 463, 1814, 1957], 'detection': [446, 795, 994], 'DNA': [451], 'peripheral': [454], 'blood': [455], 'using': [456, 484, 675, 1808, 1865, 1951], 'polymerase': [457], 'chain': [458], 'reaction': [459], 'technique.Acute': [460], 'myocarditis': [461, 517, 938, 956, 1002], 'caused': [462], 'infection': [467, 1514], 'referred': [474], 'simultaneous': [477], 'positron': [478, 1701], 'emission': [479, 1702], 'tomography/magnetic': [480], 'resonance': [481, 1142], '(PET/MR)': [482], 'imaging': [483, 875, 905, 943, 948, 1020, 1053, 1081, 1374, 1396, 1509, 1807, 1950], 'an': [485, 543, 601, 676, 872, 945, 1009, 1058], 'integrated': [486, 969, 1866], 'whole-body': [487], 'PET/MR-scanner.': [488], 'To': [489], 'minimize': [490], 'physiological': [491, 917], 'uptake': [493, 631, 705, 731, 893, 918, 930], '18F-fluoro-deoxyglucose': [495, 703], '(FDG),': [496], 'maintain': [501], 'high-fat,': [503], 'low-carbohydrate': [504], 'diet': [505, 910], '24': [506], 'hours': [507, 512], 'before': [508, 513], 'fasted': [510], '12': [511], 'PET/MR': [514, 619, 1019, 1052, 1361, 1664, 1889, 2069, 2122, 2144], 'imaging.': [515], 'MRI': [522, 662, 683, 722, 788, 838, 849, 980], 'presence': [525, 809], 'focal': [527, 568], 'intramyocardial': [528, 569, 687], 'nodules': [529, 645], 'diffuse': [533, 573, 651, 691, 811], 'subepicardial': [534, 574, 652, 692, 773], 'enhancement': [535, 638, 655, 737, 820, 835], 'lateral': [538, 578, 606, 665, 713], '(Figure,': [540, 587, 616, 624], 'A)': [541], 'inversion-recovery': [544, 677], 'sequence': [545], 'acquired': [546], '10': [547, 667], 'minutes': [548, 668], 'after': [549, 591, 669], 'injection': [550, 592, 671], 'gadolinium': [552, 637, 654, 673, 736, 819, 834], 'chelate': [553, 674], '(0.2': [554], 'mmol/L': [555], 'Magnevist;': [557], 'Bayer': [558], 'Healthcare,': [559], 'Germany).': [560], 'However,': [561, 891], 'T2-weighted': [563, 680, 816, 1011], 'images': [564, 620, 719, 725], 'only': [565], 'weak': [567, 686], 'signal': [575, 693], 'compatible': [580], 'local': [582], 'edema': [583, 697], 'could': [584, 924, 1054], 'B).': [588], 'One': [589], 'hour': [590], 'FDG': [594, 630, 730, 878, 892, 920, 929, 991], '(4': [595], 'Mega-Becquerels/kg),': [596], 'PET': [598, 724, 1353, 1373, 1583, 1669, 2149], 'scan': [599], 'revealed': [600], 'intense': [602, 702], 'radiotracer': [603], 'only,': [608], 'suggestive': [609], 'active': [611], 'inflammation': [612, 1512], 'this': [614, 904, 1079, 1099], 'territory': [615], 'C).': [617], 'Fused': [618, 718], 'heart': [623], 'D)': [625], 'colocalization': [628, 728], 'within': [632], 'areas': [634, 695, 831], 'late': [636, 653, 735, 833], 'MRI.Download': [640], 'figureDownload': [641], 'PowerPointFigure.': [642], 'A,': [643, 1125, 1129, 1158, 1168, 1205, 1691, 1729, 1731, 1778, 1796, 1921, 1939, 1989, 2203, 2233, 2237], 'Intramyocardial': [644], '(white': [646, 698, 706, 738], 'arrows)': [647, 707], '(blue': [656], 'arrow)': [657], 'can': [658, 708, 758, 821, 958], 'sequence.': [678], 'B,': [679, 1239, 1565, 1792, 1935], 'acquisitions': [681], 'show': [684], 'representing': [694], 'arrows).': [699], 'C,': [700, 1123, 1166, 1241, 1299, 1427, 1470, 1533, 1683, 1685, 1759, 1766, 1772, 1903, 1909, 1915, 2108], 'An': [701], '(FDG)': [704], 'PET.': [716], 'D,': [717, 1679, 1768, 1911, 2235], 'confirm': [726, 754], 'regions': [733], 'showing': [734], 'arrows).In': [739], 'patients': [740, 854, 962, 999, 1219, 1259], 'acute': [743, 797, 955], 'myocarditis,': [744, 2216], 'endomyocardial': [745, 828, 1033, 1192], 'biopsy': [746, 829], 'is': [747, 894], 'currently': [748], 'considered': [749, 960], 'gold': [751], 'standard': [752], 'diagnosis': [756], 'but': [757, 799, 1003], 'associated': [760], 'significant': [762], 'complications.': [763], 'In': [764, 807, 867, 998, 1035], 'addition,': [765], 'sampling': [766], 'error,': [767], 'particularly': [768], 'event': [771], 'involvement': [774], 'ventricle,': [778], 'may': [779], 'impede': [780], 'verification': [781], 'correct': [784], 'diagnosis.Alternatively,': [785], 'contrast-enhanced': [786], 'has': [789], 'demonstrated': [790], 'strong': [791], 'sensitivity': [792, 844, 989, 1030], 'myocarditis1': [798], 'have': [803], 'its': [804], 'own': [805], 'limitations.': [806], 'inflammatory': [812, 889, 932, 952, 996, 1007, 1043, 1222], 'lesions': [813, 985], 'insignificant': [815, 1010], 'images,': [817], 'delayed': [818, 1016], 'difficult': [823], 'appreciate.': [825], 'Furthermore,': [826, 968], 'targeted': [827], 'did': [839], 'not': [840], 'necessarily': [841], 'improve': [842, 1028], 'diagnostic': [843, 1199, 2225], 'regarding': [845], 'myocarditis.2': [846], 'Besides,': [847], 'cannot': [850], 'performed': [852, 912], 'certain': [856], 'implanted': [857], 'devices': [858], 'such': [859, 886], 'defibrillators': [862], 'or': [863, 1045, 1621], 'severe': [864], 'renal': [865], 'insufficiency.': [866], 'these': [868], 'patients,': [869], 'FDG-PET': [870, 942, 1859], 'represents': [871, 944], 'interesting': [873, 946], 'alternative': [874], 'technique.': [876], 'Indeed,': [877], 'accumulates': [879], 'cells': [881, 933], 'high': [883, 976, 988], 'metabolic': [884], 'activity': [885, 1068], 'activated': [888], 'cells.': [890], 'also': [895], 'common': [896], 'unaffected': [898], 'myocardium,': [899], 'limiting': [900], 'specificity': [902], 'approach.': [906], 'dedicated': [909], 'case,': [915], 'myocardium': [923], 'completely': [926], 'suppressed': [927], 'whereas': [928], 'into': [931], 'clearly': [935], 'localized': [936], 'affected': [939], 'areas.In': [940], 'summary,': [941], 'noninvasive': [947], 'technique': [949, 1082], 'identify': [951], 'processes': [953], 'contraindications': [964], 'MRI.': [967], 'PET-MRI': [970], 'systems': [971], 'offer': [972], 'combine': [974], 'spatial': [977], 'resolution': [978], 'identification': [983], 'processes.': [997], 'faint': [1006], 'activity,': [1008], 'image': [1012], 'discrepance': [1014], 'enhancement,': [1017], 'combined': [1018], 'might': [1021, 1026], 'more': [1023], 'sensitive.': [1024], 'It': [1025], 'therefore': [1027], 'imaging-guided': [1032], 'biopsy.': [1034], 'setting': [1037], 'immunosuppressive': [1039, 1216], 'treatment': [1040, 1249], 'virus-negative': [1042, 1221], 'cardiomyopathy': [1044], 'interferon-β': [1046], 'therapy': [1047, 1067, 1217], 'persisting': [1049], 'viral': [1050, 1264], 'myocarditis,3,4': [1051], 'prove': [1055], 'attractive': [1059], 'monitoring': [1060], 'tool': [1061], 'efficacy': [1064, 1214], 'drug': [1066], 'without': [1069], 'need': [1071, 1084], 'invasive': [1073], 'procedures.': [1074], 'The': [1075, 1483, 1698, 1710], 'precise': [1076], 'role': [1077, 1699], 'new': [1080], 'will': [1083], 'defined': [1087], 'future': [1089], 'clinical': [1090, 2119], 'studies.DisclosuresNone.Footnotes*Drs': [1091], 'contributed': [1096], 'equally': [1097], 'study.Correspondence': [1100], '1.': [1106], 'Klinik,': [1108], 'Ismaningerstrasse': [1112], '22,': [1113], '81675': [1114], 'Germany.': [1116], 'E-mail': [1117], '[email': [1118], 'protected]References1.': [1119], 'Mahrholdt': [1120, 1171], 'H,': [1121, 1131, 1172, 1433, 1798, 1941], 'Goedecke': [1122], 'Wagner': [1124], 'Meinhardt': [1126], 'G,': [1127, 1301, 1439, 1466, 1537], 'Athanasiadis': [1128, 1167], 'Vogelsberg': [1130], 'Fritz': [1132], 'P,': [1133, 1543, 1687, 1848, 1985], 'Klingel': [1134, 1177], 'K,': [1135, 1178, 1468, 1633, 1774, 1880, 1917], 'Kandolf': [1136, 1179], 'R,': [1137, 1180, 1388, 1476, 1568, 1725, 1784, 1786, 1927, 1929], 'Sechtem': [1138, 1183], 'U.': [1139, 1184], 'magnetic': [1141], 'assessment': [1143, 1706], 'human': [1145], 'myocarditis:': [1146, 1861], 'comparison': [1148, 2219], 'histology': [1150], 'molecular': [1152], 'pathology.Circulation.': [1153], '2004;': [1154], '109:1250–1258.LinkGoogle': [1155], 'Scholar2.': [1156], 'Yilmaz': [1157], 'Kindermann': [1159, 1161], 'I,': [1160, 1501], 'M,': [1162, 1174, 1176, 1182, 1235, 1243, 1281, 1681, 1723, 1727, 1780, 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