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2791, 2932, 3137, 3209, 3237], 'domain': [7, 18, 119, 130, 302, 470, 521, 552, 869, 3978], 'containing': [8, 120, 303], 'proteins': [9, 100, 121, 212, 336, 376, 542, 2043, 4079], '(PNPLA1–9).': [10, 122], 'Members': [11, 123], 'of': [12, 27, 64, 73, 84, 87, 98, 124, 139, 176, 185, 196, 199, 210, 227, 236, 241, 273, 280, 287, 296, 320, 344, 379, 386, 415, 421, 451, 455, 462, 519, 527, 537, 567, 626, 630, 642, 680, 684, 691, 696, 705, 718, 870, 1022, 1059, 1112, 1239, 1352, 1422, 1513, 1534, 1539, 1555, 1659, 1709, 1770, 1774, 1964, 2041, 2048, 2242, 2284, 2369, 2405, 2459, 2505, 2547, 2632, 2668, 2722, 2764, 2787, 2839, 2890, 2927, 3024, 3132, 3232, 3285, 3312, 3369, 3506, 3554, 3600, 3675, 3719, 3804, 3854, 3880, 3918, 3925, 3960, 3968, 4014, 4078, 4084], 'this': [13, 125, 387, 520, 3002, 3704], 'family': [14, 126, 295, 353, 382, 530, 663, 687, 1066, 1359, 2291, 2371, 2461, 2554, 2634, 2724, 2841, 2934, 3139, 3239, 3556], 'share': [15, 127], 'a': [16, 33, 128, 145, 271, 293, 436, 500, 505, 556, 561, 601, 606, 637, 1009, 1113, 1303, 1308, 1674, 1710, 2045, 2243, 2249, 2491, 2506, 2512, 2877, 3286, 3356, 3487, 3587, 3784, 4063], 'protein': [17, 26, 129, 138, 388, 662, 1305, 4067, 4109], 'discovered': [19, 131, 540, 2861, 3963], 'initially': [20, 132], 'in': [21, 107, 133, 219, 233, 245, 317, 337, 349, 358, 435, 650, 668, 677, 709, 714, 721, 736, 781, 835, 866, 875, 978, 1187, 1272, 1316, 1426, 1560, 1666, 1673, 1782, 1938, 1943, 1947, 1989, 1994, 2044, 2101, 2133, 2138, 2142, 2185, 2190, 2194, 2490, 2769, 2981, 3080, 3108, 3186, 3213, 3315, 3323, 3332, 3412, 3482, 3523, 3685, 3717, 3779, 3836, 3851, 3858, 3861, 3869, 3873, 3903, 3923, 3929, 3937, 4024, 4055, 4114], 'patatin,': [22, 134, 391, 429, 457], 'the': [23, 28, 70, 81, 88, 135, 140, 182, 193, 200, 234, 341, 372, 380, 393, 416, 422, 459, 463, 466, 525, 528, 538, 568, 623, 627, 643, 678, 681, 685, 689, 694, 702, 710, 867, 1273, 1317, 2757, 2788, 3021, 3051, 3105, 3904, 3915, 3966], 'most': [24, 136, 3901], 'abundant': [25, 137, 433], 'potato': [29, 141, 390, 424, 456], 'tuber.': [30, 142], 'Patatin': [31, 143], 'is': [32, 144, 499, 553, 600, 666, 833, 936, 981, 1014, 2882, 2984, 3083, 3189, 3317, 3321, 3361, 3415, 3476, 3486, 3510, 3592, 3679, 3773, 3783, 3888, 4018, 4047], 'lipid': [34, 49, 108, 146, 161, 220, 228, 246, 283, 297, 321, 417, 501, 602, 795, 837, 877, 1668, 3101, 3871, 3935, 4065, 4082], 'hydrolase': [35, 147, 419, 503, 544, 604, 654, 2367, 2457, 2630, 2720, 2837, 3552, 3866, 3977], 'with': [36, 51, 75, 148, 163, 187, 504, 605, 707, 798, 840, 880, 892, 938, 1160, 1278, 1833, 1894, 2098, 2409, 2672, 3045, 3450, 3641, 3703, 3722, 3747, 4081], 'an': [37, 149, 453, 1005, 2406, 2669, 2873, 3352, 3583], 'unusual': [38, 150], 'folding': [39, 151, 620], 'topology': [40, 152, 621], 'that': [41, 153, 497, 598, 1823, 1884, 1940, 2135, 2187, 3885, 4054], 'differs': [42, 154], 'from': [43, 155, 647, 742, 2248, 2511], 'classical': [44, 156, 569], 'lipases.': [45, 157, 3897], 'Mammalian': [46, 158], 'PNPLAs': [47, 159], 'include': [48, 160, 248], 'hydrolases': [50, 162, 251], 'specificities': [52, 164], 'for': [53, 165, 334, 907, 1118, 3291, 3489, 3786], 'diverse': [54, 166, 230, 318], 'substrates': [55, 167], 'such': [56, 168], 'as': [57, 169, 255, 257, 308, 355, 522, 524, 898, 900, 3515, 3517], 'triacylglycerols,': [58, 170], 'phospholipids,': [59, 171], 'and': [60, 69, 101, 109, 172, 181, 213, 221, 238, 260, 275, 285, 323, 327, 346, 367, 401, 432, 493, 594, 622, 701, 723, 750, 777, 896, 905, 943, 1018, 1057, 1071, 1145, 1162, 1282, 1311, 1350, 1364, 1391, 1582, 1605, 1670, 1707, 1743, 1772, 1836, 1897, 1935, 1946, 2016, 2039, 2071, 2130, 2141, 2161, 2182, 2193, 2217, 2254, 2282, 2296, 2324, 2365, 2388, 2455, 2517, 2545, 2559, 2587, 2628, 2651, 2718, 2835, 2886, 2925, 2939, 2998, 3020, 3103, 3113, 3130, 3144, 3208, 3230, 3244, 3334, 3339, 3365, 3448, 3480, 3485, 3550, 3596, 3639, 3683, 3745, 3777, 3782, 3832, 3876, 3907, 3914, 3949, 3955, 4022, 4086], 'retinol': [61, 173, 261], 'esters.': [62, 174], 'Analysis': [63, 175], 'induced': [65, 177, 697, 1015, 2883, 3362, 3593], 'mutant': [66, 178, 698, 2479, 2742], 'mouse': [67, 179, 329, 699, 2046, 2480, 2743, 3524, 3720], 'models': [68, 180, 330, 3721], 'clinical': [71, 183], 'phenotype': [72, 184, 3803], 'patients': [74, 186, 706], 'mutations': [76, 188, 345, 708, 1477], 'revealed': [77, 189, 331], 'important': [78, 190, 269, 332], 'insights': [79, 191], 'into': [80, 192], 'physiological': [82, 194, 338, 682, 2762], 'role': [83, 195, 3857], 'several': [85, 197, 536], 'members': [86, 198, 310, 354, 378, 664, 1067, 1360, 2292, 2555, 2935, 3140, 3240], 'PNPLA': [89, 99, 201, 211, 335, 375, 529, 661, 686], 'family.': [90, 202], 'This': [91, 203, 671], 'review': [92, 204, 672], 'aims': [93, 205, 673], 'to': [94, 102, 206, 214, 270, 313, 362, 465, 674, 1191, 1307, 1431, 1664, 2411, 2674, 3099, 4061], 'summarize': [95, 207, 675], 'current': [96, 208], 'knowledge': [97, 209], 'document': [103, 215], 'their': [104, 216], 'emerging': [105, 217], 'importance': [106, 218], 'energy': [110, 222, 288, 363, 779, 3834], 'homeostasis.': [111, 223, 289], 'large': [225], 'group': [226, 1147, 1393, 1584, 1607, 1827, 1888, 1995, 2219, 2326, 2589], 'hydrolases,': [229, 298], 'enzymes': [231, 266], 'involved': [232], 'hydrolysis': [235, 1512, 3860, 3985], 'ester': [237, 262], 'amide': [239], 'bonds': [240], 'fatty': [242, 940, 1164, 1193], 'acids': [243], '(FA)': [244], 'molecules,': [247], 'triacylglycerol': [249, 1069, 1362, 2294, 2557, 2937, 3142, 3242], '(TG)': [250], '(lipases),': [252], 'phospholipases,': [253], 'ceraminidases': [254], 'well': [256, 523, 899, 3516], 'cholesterol': [258], 'ester,': [259], '(RE)': [263], 'hydrolases.': [264], 'These': [265], 'are': [267, 377, 1276, 1992, 2486, 2749, 3330, 3710], 'generally': [268], 'plethora': [272], 'intra-': [274], 'extracellular': [276], 'processes,': [277], 'including': [278], 'maintenance': [279], 'membrane': [281, 1116, 1514, 2037, 3289], 'integrity,': [282, 366], 'signaling,': [284], 'regulation': [286, 3445, 3636, 3742], 'In': [290, 3043], 'recent': [291, 2999], 'years,': [292], 'mammalian': [294, 541, 660], 'designated': [299], '(PNPLA),': [304], 'has': [305], 'attracted': [306], 'attention,': [307], 'its': [309, 1146, 1392, 1583, 1606, 2218, 2325, 2588, 3046, 3855], 'were': [311], 'found': [312, 649, 3331], 'serve': [314], 'critical': [315, 3856], 'roles': [316], 'aspects': [319], 'metabolism': [322, 780, 1669, 3835], 'signaling.': [324], 'Several': [325], 'gain-': [326], 'loss-of-function': [328], 'implications': [333], 'processes.': [339], 'Moreover,': [340], 'phenotypic': [342], 'consequences': [343], 'gene': [347, 827, 935, 1007, 1275, 1476, 2245, 2484, 2508, 2747, 2875, 3354, 3585, 3971], 'polymorphisms': [348], 'humans': [350], 'identified': [351], 'enzyme': [352, 464, 3003, 3052], 'key': [356], 'players': [357], 'disease': [359, 703, 797, 839, 879, 1166], 'states': [360], 'linked': [361], 'homeostasis,': [364, 1932, 2127, 2179], 'neuronal': [365], 'age-related': [368, 1962], 'bone': [369, 1965, 1990], 'morphology.': [370], 'As': [371], 'name': [373, 518], 'implies,': [374], 'patatin': [381, 498, 599, 631, 868, 1011, 2879, 3358, 3589], '(Pfam01734).': [383], 'eponym': [385], 'family,': [389], 'harbors': [392], 'evolutionarily': [394], 'conserved': [395], 'consensus': [396], 'serine': [397], 'lipase': [398, 652, 831, 873, 1070, 1363, 2295, 2558, 2938, 3019, 3055, 3143, 3243, 3474, 3771, 3893], 'motif': [399], 'Gly-X-Ser-X-Gly': [400], 'exhibits': [402, 3206], 'nonspecific': [403], 'acyl-hydrolase': [404], 'activity': [405, 420, 494, 595, 2368, 2458, 2631, 2721, 2838, 3212, 3553, 3867, 3989], '(1Andrews': [406], 'D.L.': [407, 4069], 'Beames': [408], 'B.': [409, 1051, 1344, 1544, 1978, 2276, 2539, 2919, 3124, 3224], 'Summers': [410], 'M.D.': [411], 'Park': [412], 'W.D.': [413], 'Characterization': [414, 2786], 'acyl': [418, 502, 603], 'major': [423, 4064], '(Solanum': [425], 'tuberosum)': [426], 'tuber': [427], 'protein,': [428, 1013, 2881, 3360, 3591], 'by': [430, 555, 983, 1016, 2053, 2884, 2986, 3085, 3191, 3363, 3417, 3446, 3478, 3491, 3594, 3637, 3681, 3712, 3743, 3775, 3788, 3891, 4020], 'cloning': [431], 'expression': [434, 1021, 1708, 2889, 3328, 3368, 3599], 'baculovirus': [437], 'vector.Biochem.': [438], 'J.': [439, 764, 812, 1170, 1242, 1284, 1301, 1482, 1502, 1546, 1550, 1759, 1820, 1881, 1930, 1950, 1986, 2001, 2021, 2056, 2125, 2145, 2177, 2197, 3493, 3790, 3819], '1988;': [440], '252:': [441], '199-206Crossref': [442], 'PubMed': [443, 512, 613, 790, 846, 887, 950, 990, 1037, 1085, 1132, 1155, 1200, 1253, 1289, 1330, 1378, 1401, 1437, 1493, 1526, 1569, 1592, 1615, 1689, 1728, 1800, 1851, 1912, 1957, 2011, 2066, 2107, 2152, 2204, 2227, 2261, 2310, 2334, 2383, 2425, 2473, 2524, 2573, 2597, 2646, 2688, 2736, 2803, 2853, 2905, 2953, 2993, 3038, 3092, 3158, 3198, 3258, 3305, 3384, 3424, 3455, 3500, 3568, 3615, 3646, 3697, 3752, 3797, 3845, 4036, 4101], 'Scopus': [444, 513, 614, 791, 847, 888, 951, 991, 1038, 1086, 1133, 1156, 1201, 1254, 1290, 1331, 1379, 1402, 1438, 1494, 1527, 1570, 1593, 1616, 1690, 1729, 1801, 1852, 1913, 1958, 2012, 2067, 2108, 2153, 2205, 2228, 2262, 2311, 2335, 2384, 2426, 2474, 2525, 2574, 2598, 2647, 2689, 2737, 2804, 2854, 2906, 2954, 2994, 3039, 3093, 3159, 3199, 3259, 3306, 3385, 3425, 3456, 3501, 3569, 3616, 3647, 3698, 3753, 3798, 3846, 4037, 4102], '(208)': [445], 'Google': [446, 515, 616, 793, 849, 890, 953, 993, 1040, 1088, 1135, 1158, 1203, 1256, 1292, 1333, 1381, 1404, 1440, 1496, 1529, 1572, 1595, 1618, 1692, 1731, 1803, 1854, 1915, 1960, 2014, 2069, 2110, 2155, 2207, 2230, 2264, 2313, 2337, 2386, 2428, 2476, 2527, 2576, 2600, 2649, 2691, 2739, 2806, 2856, 2908, 2956, 2996, 3041, 3095, 3161, 3201, 3261, 3308, 3387, 3427, 3458, 3503, 3571, 3618, 3649, 3700, 3755, 3800, 3848, 4039, 4104], 'Scholar).': [447, 516, 617, 2857, 3042, 3096, 3202, 3309, 3504, 3701, 3801, 4040, 4105], '3-D': [449, 624], 'structure': [450], 'Pat17,': [452], 'isoenzyme': [454], 'localized': [458], 'active': [460], 'site': [461, 629], 'so-called': [467], '(2Rydel': [471, 572], 'T.J.': [472, 573], 'Williams': [473, 574], 'J.M.': [474, 575, 818], 'Krieger': [475, 576], 'E.': [476, 577, 816, 1180, 1456, 2238, 2501], 'Moshiri': [477, 578], 'F.': [478, 579, 971, 1297, 2974, 3073, 3179, 3405], 'Stallings': [479, 580], 'W.C.': [480, 581, 2236, 2499], 'Brown': [481, 582], 'S.M.': [482, 583], 'Pershing': [483, 584], 'J.C.': [484, 585, 1182, 1218, 2087], 'Purcell': [485, 586], 'J.P.': [486, 587], 'Alibhai': [487, 588], 'M.F.': [488, 589], 'crystal': [490, 591], 'structure,': [491, 592, 2758], 'mutagenesis,': [492, 593], 'studies': [495, 596, 1232], 'reveal': [496, 597, 1233], 'Ser-Asp': [506, 563, 607], 'catalytic': [507, 562, 564, 570, 608, 628, 634, 644], 'dyad.Biochemistry.': [508, 609], '2003;': [509, 610, 1434], '42:': [510, 611], '6696-6708Crossref': [511, 612], '(215)': [514, 615, 2805], 'nomenclature': [526], 'is,': [531], 'unfortunately,': [532], 'somewhat': [533], 'misleading,': [534], 'because': [535], 'subsequently': [539], 'exhibit': [543], 'but': [545, 2808], 'not': [546, 1825, 1886, 2809, 3889], 'activity.': [548], 'characterized': [554], 'three-layer': [557], 'α/β/α': [558], 'architecture': [559], 'employing': [560], 'dyad': [565], 'instead': [566], 'triad': [571], 'observed': [619, 2775, 3511], 'arrangement': [625], '(oxyanion': [632], 'hole,': [633], 'Ser': [635], 'within': [636], 'nucleophilic': [638], 'elbow,': [639], 'spatial': [640], 'position': [641], 'Asp)': [645], 'differ': [646], 'those': [648], 'canonical': [651], 'α/β': [653, 3976], 'folds.': [655], 'phylogenetic': [657], 'relationship': [658], 'among': [659], '(PNPLA1–9)': [665], 'displayed': [667, 3950], 'Fig.': [669], '1.': [670], 'advances': [676], 'understanding': [679], 'function': [683, 1671], 'on': [688, 2256, 2519, 2756, 3001], 'basis': [690], 'biochemical': [692], 'studies,': [693], 'characterization': [695], 'models,': [700], 'pattern': [704], 'respective': [711], 'genes': [712], '(summarized': [713], 'Table': [715], '1).TABLE': [716], '1Phenotypes': [717], 'genetic': [719, 2099], 'variants': [720, 2485, 2748], 'murine': [722], 'PNPLAsProteinMouse': [725], 'ModelsHuman': [726], 'MutationsHuman': [727], 'PolymorphismsPNPLA2Global': [728], 'deletion:': [729, 1406, 1531, 1620, 1856], 'decreased': [730, 893, 1623, 1734, 1860], 'plasma': [731, 894, 903, 1237], 'FA': [732, 895, 3114], 'levels,': [733], 'TG': [734, 897, 1741, 3109, 3859, 3865, 3898, 3984], 'accumulation': [735, 1742, 1769, 2040, 3899, 3936], 'multiple': [737, 1632, 3324, 3862, 3938], 'tissues,': [738, 3941], 'obesity,': [739, 1258], 'premature': [740, 3916], 'death': [741, 3917], 'heart': [743, 3905, 3912], 'failure,': [744, 3913], 'defective': [745, 3684, 3930, 4023], 'cold': [746, 3931], 'adaptation,': [747], 'enhanced': [748, 3870, 3951], 'glucose': [749, 904, 1861, 2159, 3947, 3956], 'insulin': [751, 1259, 1280, 1864, 1933, 2128, 2162, 2180, 3479, 3713, 3724, 3776, 3939, 3953], 'tolerance': [752, 2160], '(13Haemmerle': [753, 3808], 'G.': [754, 760, 766, 960, 962, 969, 1814, 1875, 2093, 2963, 2965, 2972, 3012, 3062, 3064, 3071, 3168, 3170, 3177, 3394, 3396, 3403, 3656, 3660, 3668, 3809, 3815, 3821, 3995, 3999, 4007, 4071], 'Lass': [755, 966, 2393, 2656, 2969, 3015, 3068, 3174, 3400, 3810], 'A.': [756, 918, 967, 973, 1174, 1924, 2075, 2119, 2171, 2394, 2657, 2970, 2976, 3016, 3069, 3075, 3175, 3181, 3401, 3407, 3652, 3811, 3991], 'Zimmermann': [757, 925, 2400, 2663, 3013, 3653, 3812, 3992], 'R.': [758, 768, 825, 926, 928, 956, 1099, 2401, 2403, 2664, 2666, 2959, 3008, 3014, 3058, 3164, 3272, 3390, 3654, 3670, 3813, 3823, 3993, 4009, 4075], 'Gorkiewicz': [759, 3667, 3814, 4006], 'Meyer': [761, 1100, 3273, 3816], 'C.': [762, 770, 814, 916, 1101, 1172, 1420, 1464, 3274, 3817, 3825], 'Rozman': [763, 3818], 'Heldmaier': [765, 3820], 'Maier': [767, 3822], 'Theussl': [769, 3824], 'Eder': [771, 3826], 'S.': [772, 998, 1105, 1168, 1295, 1452, 1806, 1816, 1867, 1877, 1918, 1968, 1982, 2085, 2113, 2165, 2866, 3278, 3345, 3576, 3827], 'al': [773, 931, 974, 1108, 1227, 1471, 1655, 1766, 2094, 2361, 2451, 2624, 2714, 2831, 2977, 3076, 3182, 3281, 3408, 3546, 3828], 'et': [774, 932, 975, 1110, 1228, 1472, 1656, 1767, 2095, 2362, 2452, 2625, 2715, 2832, 2978, 3077, 3183, 3283, 3409, 3547, 3829], 'Defective': [775, 3830], 'lipolysis': [776, 3674, 3831, 3922, 4013], 'altered': [778, 1627, 3833], 'mice': [782, 1427, 1822, 1883, 1939, 2134, 2186, 3807, 3837, 3927, 3943], 'lacking': [783, 3838], 'adipose': [784, 829, 871, 979, 984, 1318, 2982, 2987, 3053, 3081, 3086, 3187, 3192, 3336, 3413, 3418, 3471, 3768, 3839], 'triglyceride': [785, 830, 872, 985, 1025, 2366, 2456, 2629, 2719, 2836, 2893, 2988, 3018, 3054, 3087, 3193, 3372, 3419, 3442, 3473, 3551, 3603, 3633, 3672, 3739, 3770, 3840, 4011], 'lipase.Science.': [786, 986, 2989, 3088, 3194, 3420, 3841], '2006;': [787, 947, 1124, 1152, 1398, 1589, 1612, 2224, 2331, 2594, 2795, 3297, 3452, 3497, 3643, 3689, 3749, 3794, 3842, 4028], '312:': [788, 3843], '734-737Crossref': [789, 3844], '(1011)': [792, 3847], 'Scholar).Neutral': [794], 'storage': [796, 838, 878], 'myopathy,': [799], 'further': [800], 'various': [801, 2770], 'symptoms:': [802], 'cardiomyopathy,': [803, 3910], 'short': [804], 'stature,': [805], 'hepatomegaly,': [806], 'splenomegalie,': [807], 'diabetes,': [808], 'chronic': [809], 'pancreatitis': [810], '(18Fischer': [811], 'Lefevre': [813], 'Morava': [815], 'Mussini': [817], 'Laforet': [819], 'P.': [820, 1222, 1506, 2083, 3664, 4003], 'Lathrop': [821], 'A.Negre-Salvayre,': [822], 'M.': [823, 852, 856, 965, 1270, 1299, 1454, 1500, 1812, 1873, 1922, 1974, 2027, 2117, 2169, 2968, 3067, 3173, 3399, 3438, 3629, 3658, 3662, 3735, 3997, 4001], 'Salvayre': [824], 'encoding': [828, 1008, 2876, 3355, 3586], '(PNPLA2)': [832, 874], 'mutated': [834], 'neutral': [836, 876], 'myopathy.Nat.': [841], 'Genet.': [842, 1196, 1244, 1433, 1484], '2007;': [843, 884, 1681, 1792], '39:': [844], '28-30Crossref': [845], '(365)': [848], 'Scholar,': [850, 1916, 2909, 2957, 3162, 3262, 3388, 3428, 3459, 3572, 3619, 3650, 3756], '20Akiyama': [851], 'Sakai': [853], 'K.': [854, 1216, 1542, 1646, 1763, 1765, 1818, 1879, 3463, 3760], 'Ogawa': [855], 'McMillan': [857], 'J.R.': [858, 1212], 'Sawamura': [859], 'D.': [860, 1176, 1210, 1458, 1460, 2352, 2442, 2615, 2705, 2822, 3537], 'Shimizu': [861], 'H.': [862, 1224, 2397, 2660], 'Novel': [863], 'duplication': [864], 'mutation': [865], 'severe': [881, 3909], 'myopathy.Muscle': [882], 'Nerve.': [883], '36:': [885], '856-859Crossref': [886], '(72)': [889], 'Scholar).Association': [891], 'increased': [901, 1279, 2158, 3716, 3946], 'fasting': [902, 1017, 2885, 3364, 3522, 3595], 'risk': [906], 'type': [908, 944], '2': [909, 945], 'diabetes': [910], '(22Schoenborn': [911], 'V.': [912, 1093, 3266], 'Heid': [913], 'I.M.': [914], 'Vollmert': [915], 'Lingenhel': [917], 'Adams': [919], 'T.D.': [920], 'Hopkins': [921], 'P.N.': [922], 'Illig': [923], 'T.': [924, 1226, 1650, 2354, 2444, 2617, 2707, 2824, 3539], 'Zechner': [927, 2402, 2665, 3669, 4008], 'Hunt': [929], 'S.C.': [930], 'ATGL': [934, 3097, 3204, 3319, 3507, 3707, 3886, 3961, 4045], 'associated': [937, 1277, 2097, 4080], 'free': [939], 'acids,': [941], 'triglycerides,': [942], 'diabetes.Diabetes.': [946], '55:': [948, 3453, 3644, 3750], '1270-1275Crossref': [949], '(87)': [952], 'Scholar).ATGL': [954], '(7Zimmermann': [955, 3057], 'Strauss': [957, 2960, 3059, 3165, 3391, 3665, 4004], 'J.G.': [958, 2961, 3060, 3166, 3392, 3666, 4005], 'Haemmerle': [959, 2962, 3011, 3061, 3167, 3393, 3655, 3994], 'Schoiswohl': [961, 2964, 3063, 3169, 3395, 3659, 3998], 'Riederer': [963, 2966, 3065, 3171, 3397, 3657, 3996], 'R.Birner-Gruenberger,': [964, 2967, 3066, 3172, 3398], 'Neuberger': [968, 2971, 3070, 3176, 3402], 'Eisenhaber': [970, 2973, 3072, 3178, 3404], 'Hermetter': [972, 2975, 3074, 3180, 3406], 'Fat': [976, 2979, 3078, 3184, 3410], 'mobilization': [977, 2980, 3079, 3185, 3411], 'tissue': [980, 2983, 3082, 3188, 3337, 3414, 3472, 3769], 'promoted': [982, 2985, 3084, 3190, 3416], '2004;': [987, 1029, 1077, 1370, 1566, 1843, 1904, 2302, 2565, 2897, 2945, 2990, 3089, 3150, 3195, 3250, 3376, 3421, 3607, 4093], '306:': [988, 2991, 3090, 3196, 3422], '1383-1386Crossref': [989, 2992, 3091, 3197, 3423], '(1504)': [992, 2995, 3094, 3200, 3426], 'Scholar)Desnutrin': [994], '(5Villena': [995, 2863, 3342], 'J.A.': [996, 2864, 3343, 3574], 'Roy': [997, 2865, 3344, 3575], 'Kim': [999, 2347, 2437, 2610, 2700, 2817, 2867, 3346, 3532, 3577], 'E.Sarkadi-Nagy,': [1000, 2868, 3347, 3578], 'K.H.': [1001, 2869, 3348, 3579], 'Sul': [1002, 2870, 3349, 3580], 'H.S.': [1003, 2871, 3350, 3581], 'Desnutrin,': [1004, 2872, 3351, 3582], 'adipocyte': [1006, 2874, 3353, 3513, 3584], 'novel': [1010, 1061, 1309, 1354, 1711, 2286, 2549, 2878, 2929, 3134, 3234, 3357, 3588], 'domain-containing': [1012, 2880, 3359, 3590], 'glucocorticoids:': [1019, 2887, 3366, 3597], 'ectopic': [1020, 2888, 3367, 3598], 'desnutrin': [1023, 2891, 3370, 3601], 'increases': [1024, 2892, 3371, 3602], 'hydrolysis.J.': [1026, 2894, 3373, 3604], 'Biol.': [1027, 1075, 1122, 1320, 1368, 1516, 1679, 1718, 1790, 1841, 1902, 2300, 2415, 2563, 2678, 2895, 2943, 3148, 3248, 3295, 3374, 3605, 4091], 'Chem.': [1028, 1076, 1123, 1321, 1369, 1517, 1680, 1719, 1791, 1842, 1903, 2301, 2416, 2564, 2679, 2896, 2944, 3149, 3249, 3296, 3375, 3606, 4092], '279:': [1030, 1078, 1371, 1844, 1905, 2303, 2566, 2898, 2946, 3151, 3251, 3377, 3608, 4094], '47066-47075Abstract': [1031, 2899, 3378, 3609], 'Full': [1032, 1034, 1080, 1082, 1127, 1129, 1248, 1250, 1325, 1327, 1373, 1375, 1488, 1490, 1521, 1523, 1684, 1686, 1723, 1725, 1795, 1797, 1846, 1848, 1907, 1909, 2006, 2008, 2061, 2063, 2305, 2307, 2378, 2380, 2420, 2422, 2468, 2470, 2568, 2570, 2641, 2643, 2683, 2685, 2731, 2733, 2798, 2800, 2848, 2850, 2900, 2902, 2948, 2950, 3033, 3035, 3153, 3155, 3253, 3255, 3300, 3302, 3379, 3381, 3563, 3565, 3610, 3612, 3692, 3694, 4031, 4033, 4096, 4098], 'Text': [1033, 1035, 1081, 1083, 1128, 1130, 1249, 1251, 1326, 1328, 1374, 1376, 1489, 1491, 1522, 1524, 1685, 1687, 1724, 1726, 1796, 1798, 1847, 1849, 1908, 1910, 2007, 2009, 2062, 2064, 2306, 2308, 2379, 2381, 2421, 2423, 2469, 2471, 2569, 2571, 2642, 2644, 2684, 2686, 2732, 2734, 2799, 2801, 2849, 2851, 2901, 2903, 2949, 2951, 3034, 3036, 3154, 3156, 3254, 3256, 3301, 3303, 3380, 3382, 3564, 3566, 3611, 3613, 3693, 3695, 4032, 4034, 4097, 4099], 'PDF': [1036, 1084, 1131, 1252, 1329, 1377, 1492, 1525, 1688, 1727, 1799, 1850, 1911, 2010, 2065, 2309, 2382, 2424, 2472, 2572, 2645, 2687, 2735, 2802, 2852, 2904, 2952, 3037, 3157, 3257, 3304, 3383, 3567, 3614, 3696, 4035, 4100], '(505)': [1039, 2907, 3386, 3617], 'Scholar)iPLA2ζ': [1041], '(6Jenkins': [1042, 1335, 2267, 2530, 3115, 3215], 'C.M.': [1043, 1336, 1642, 1697, 1751, 2268, 2531, 2911, 3116, 3216, 3469, 3766], 'Mancuso': [1044, 1337, 2022, 2269, 2532, 2912, 3117, 3217], 'D.J.': [1045, 1338, 1636, 1695, 1747, 1808, 1869, 2023, 2270, 2533, 2785, 2913, 3118, 3218], 'Yan': [1046, 1339, 1760, 2271, 2534, 2914, 3119, 3219], 'W.': [1047, 1220, 1340, 1761, 1926, 2121, 2173, 2272, 2358, 2448, 2535, 2621, 2711, 2828, 2915, 3120, 3220, 3543], 'Sims': [1048, 1341, 1637, 1756, 2273, 2536, 2916, 3121, 3221], 'H.F.': [1049, 1342, 1638, 1757, 2274, 2537, 2917, 3122, 3222], 'Gibson': [1050, 1343, 2275, 2538, 2918, 3123, 3223], 'Gross': [1052, 1345, 1698, 2032, 2277, 2540, 2920, 3125, 3225], 'R.W.': [1053, 1346, 1699, 2033, 2278, 2541, 2921, 3126, 3226], 'Identification,': [1054, 1347, 2279, 2542, 2922, 3127, 3227], 'cloning,': [1055, 1348, 1706, 2280, 2543, 2923, 3128, 3228], 'expression,': [1056, 1349, 2281, 2544, 2924, 3129, 3229], 'purification': [1058, 1351, 2283, 2546, 2926, 3131, 3231], 'three': [1060, 1353, 2285, 2548, 2928, 3133, 3233], 'calcium-independent': [1063, 1356, 1660, 1715, 1787, 2288, 2551, 2931, 3136, 3236], 'A2': [1065, 1143, 1358, 1389, 1580, 1603, 1830, 1891, 1998, 2215, 2290, 2322, 2553, 2585, 2933, 3138, 3238], 'possessing': [1068, 1361, 2293, 2556, 2936, 3141, 3241], 'acylglycerol': [1072, 1365, 2297, 2560, 2940, 3145, 3245], 'transacylase': [1073, 1366, 2298, 2561, 2941, 3146, 3207, 3246], 'activities.J.': [1074, 1367, 2299, 2562, 2942, 3147, 3247], '48968-48975Abstract': [1079, 1372, 2304, 2567, 2947, 3152, 3252], '(677)': [1087, 1380, 2312, 2575, 2955, 3160, 3260], 'Scholar)PEDF-R': [1089], '(9Notari': [1090], 'L.': [1091, 1268, 1462, 1548, 2025, 3264, 4073], 'Baladron': [1092, 3265], 'Balko': [1094, 3267], 'J.D.': [1095, 3268], 'Aroca-Aguilar,': [1096, 3269], 'N.': [1097, 1214, 1470, 1755, 2091, 3270], 'Heredia': [1098, 3271], 'Notario': [1102, 3275], 'P.M.': [1103, 3276], 'Saravanamuthu': [1104, 3277], 'Nueda': [1106, 3279], 'M.L.': [1107, 1412, 3280], 'F.Sanchez-Sanchez,': [1109, 3282], 'Identification': [1111, 2404, 2667, 3284], 'lipase-linked': [1114, 3287], 'cell': [1115, 1536, 3288], 'receptor': [1117, 3290], 'pigment': [1119, 3292], 'epithelium-derived': [1120, 3293], 'factor.J.': [1121, 3294], '281:': [1125, 3298], '38022-38037Abstract': [1126, 3299], '(248)': [1134, 3307], 'Scholar)PLA2GVIE': [1136], '(47Schaloske': [1137, 1383, 1574, 1597, 2209, 2316, 2579], 'R.H.': [1138, 1384, 1575, 1598, 2210, 2317, 2580], 'Dennis': [1139, 1385, 1576, 1599, 2211, 2318, 2581], 'E.A.': [1140, 1386, 1577, 1600, 2212, 2319, 2582], 'superfamily': [1144, 1390, 1581, 1604, 2216, 2323, 2586], 'numbering': [1148, 1394, 1585, 1608, 2220, 2327, 2590], 'system.Biochim.': [1149, 1395, 1586, 1609, 2221, 2328, 2591], 'Biophys.': [1150, 1396, 1587, 1610, 2222, 2329, 2592], 'Acta.': [1151, 1397, 1588, 1611, 2223, 2330, 2593], '1761:': [1153, 1399, 1590, 1613, 2225, 2332, 2595], '1246-1259Crossref': [1154, 1400, 1591, 1614, 2226, 2333, 2596], '(723)': [1157, 1403, 1594, 1617, 2229, 2336, 2599], 'Scholar)PNPLA3Association': [1159], 'hepatosteatosis': [1161], 'nonalcoholic': [1163, 1192], 'liver': [1165, 1194, 1205, 1240], '(25Romeo': [1167], 'Kozlitina': [1169], 'Xing': [1171], 'Pertsemlidis': [1173], 'Cox': [1175], 'Pennacchio': [1177], 'L.A.': [1178, 3434, 3625, 3731], 'Boerwinkle': [1179], 'Cohen': [1181], 'Hobbs': [1183], 'H.H.': [1184, 2356, 2446, 2619, 2709, 2826, 3541], 'Genetic': [1185, 1657], 'variation': [1186], 'PNPLA3': [1188], 'confers': [1189], 'susceptibility': [1190], 'disease.Nat.': [1195], '2008;': [1197, 1245, 1286, 1485, 1954, 2003, 2058, 2104, 2149, 2201, 2417, 2680], '40:': [1198], '1461-1465Crossref': [1199], '(2213)': [1202], 'Scholar),': [1204, 1257, 1961, 2015, 2265, 2314, 2429, 2528, 2577, 2692, 2997], 'transaminases': [1206], '(26Yuan': [1207], 'X.': [1208, 1640, 1749, 1980, 1984], 'Waterworth': [1209], 'Perry': [1211], 'Lim': [1213], 'Song': [1215], 'Chambers': [1217], 'Zhang': [1219, 1981], 'Vollenweider': [1221], 'Stirnadel': [1223], 'Johnson': [1225, 2349, 2439, 2612, 2702, 2819, 3534], 'Population-based': [1229], 'genome-wide': [1230], 'association': [1231], 'six': [1234], 'loci': [1235], 'influencing': [1236], 'levels': [1238, 2768, 3329, 3509, 3709], 'enzymes.Am.': [1241], 'Hum.': [1243, 1483], '83:': [1246], '520-528Abstract': [1247], '(328)': [1255], 'secretion': [1260, 1281, 1865, 2163], '(27Johansson': [1261], 'L.E.': [1262], 'Lindblad': [1263], 'U.': [1264], 'Larsson': [1265], 'C.A.': [1266], 'Rastam': [1267], 'Ridderstrale': [1269], 'Polymorphisms': [1271], 'adiponutrin': [1274], 'obesity.Eur.': [1283], 'Endocrinol.': [1285, 1952, 2147, 2199, 3495, 3792], '159:': [1287], '577-583Crossref': [1288], '(70)': [1291], 'Scholar).Adiponutrin': [1293], '(24Baulande': [1294], 'Lasnier': [1296], 'Lucas': [1298], 'Pairault': [1300], 'Adiponutrin,': [1302], 'transmembrane': [1304], 'corresponding': [1306], 'dietary-': [1310], 'obesity-linked': [1312], 'mRNA': [1313, 1704, 2767, 3320, 3708], 'specifically': [1314], 'expressed': [1315, 3322], 'lineage.J.': [1319], '2001;': [1322], '276:': [1323], '33336-33344Abstract': [1324], '(201)': [1332], 'Scholar)iPLA2ε': [1334], 'Scholar)PLA2GVID': [1382], 'Scholar)PNPLA6Global': [1405], 'embryonic': [1407], 'lethality': [1408], '(30Winrow': [1409], 'C.J.': [1410], 'Hemming': [1411], 'Allen': [1413], 'D.M.': [1414], 'Quistad': [1415], 'G.B.': [1416], 'Casida': [1417], 'J.E.': [1418, 2348, 2360, 2438, 2450, 2611, 2623, 2701, 2713, 2818, 2830, 3533, 3545], 'Barlow': [1419], 'Loss': [1421], 'neuropathy': [1423, 1508, 1556, 2412, 2675], 'target': [1424, 1474, 1509, 1557, 2413, 2676, 3488, 3785, 3940], 'esterase': [1425, 1475, 1510], 'links': [1428], 'organophosphate': [1429], 'exposure': [1430], 'hyperactivity.Nat.': [1432], '33:': [1435], '477-485Crossref': [1436], '(159)': [1439], 'Scholar).NTE-related': [1441], 'motor': [1442, 1479], 'neuron': [1443, 1480], 'disease:': [1444], 'distal': [1445], 'muscle': [1446], 'wasting,': [1447], 'progressive': [1448], 'spastic': [1449], 'paraplegia': [1450], '(34Rainier': [1451], 'Bui': [1453], 'Mark': [1455], 'Thomas': [1457], 'Tokarz': [1459], 'Ming': [1461], 'Delaney': [1463], 'Richardson': [1465], 'R.J.': [1466], 'Albers': [1467], 'J.W.': [1468, 2350, 2440, 2613, 2703, 2820, 3535], 'Matsunami': [1469], 'Neuropathy': [1473], 'cause': [1478], 'disease.Am.': [1481], '82:': [1486], '780-785Abstract': [1487], '(193)': [1495], 'Scholar).NTE': [1497], '(31van': [1498], 'Tienhoven': [1499], 'Atkins': [1501], 'Li': [1503, 2345, 2351, 2435, 2441, 2608, 2614, 2698, 2704, 2815, 2821, 3530, 3536], 'Y.': [1504, 2344, 2434, 2607, 2697, 2814, 3529], 'Glynn': [1505], 'Human': [1507], 'catalyzes': [1511, 3104], 'lipids.J.': [1515], '2002;': [1518], '277:': [1519], '20942-20948Abstract': [1520], '(152)': [1528], 'Scholar)Brain-specific': [1530], 'neurodegeneration,': [1532], 'vacuolation': [1533], 'nerve': [1535], 'bodies,': [1537], 'disruption': [1538], 'ER': [1540], '(33Akassoglou': [1541], 'Malester': [1543], 'Xu': [1545], 'Tessarollo': [1547], 'Rosenbluth': [1549], 'Chao': [1551], 'M.V.': [1552], 'Brain-specific': [1553], 'deletion': [1554], 'esterase/swisscheese': [1558], 'results': [1559], 'neurodegeneration.Proc.': [1561], 'Natl.': [1562], 'Acad.': [1563], 'Sci.': [1564], 'USA.': [1565], '101:': [1567], '5075-5080Crossref': [1568], '(149)': [1571], 'Scholar).iPLA2δ': [1573], 'Scholar)PLA2GVIC': [1596], 'Scholar)PNPLA8Global': [1619], 'mitochondrial': [1621, 1667, 1676, 1738], 'dysfunction,': [1622], 'myocardial': [1624], 'cardiolipin': [1625, 1628], 'content,': [1626], 'molecular': [1629, 4042], 'species': [1630], 'composition,': [1631], 'bioenergetic': [1633, 1677], 'defects': [1634, 2100], '(39Mancuso': [1635], 'Han': [1639, 1748], 'Jenkins': [1641, 1696, 1750], 'Guan': [1643], 'S.P.': [1644], 'Yang': [1645, 1758, 1762], 'Moon': [1647], 'S.H.': [1648], 'Pietka': [1649], 'Abumrad': [1651], 'N.A.': [1652], 'Schlesinger': [1653], 'P.H.': [1654, 2240, 2503], 'ablation': [1658], 'A2gamma': [1662], 'leads': [1663], 'alterations': [1665], 'resulting': [1672, 4113], 'deficient': [1675], 'phenotype.J.': [1678], '282:': [1682, 1793], '34611-34622Abstract': [1683], '(125)': [1691], 'Scholar).iPLA2γ': [1693], '(36Mancuso': [1694], 'genomic': [1701], 'organization,': [1702], 'complete': [1703], 'sequence,': [1705], 'intracellular': [1713], 'membrane-associated': [1714], 'A(2).J.': [1717], '2000;': [1720], '275:': [1721], '9937-9945Abstract': [1722], '(179)': [1730], 'Scholar)Cardiac': [1732], 'overexpression:': [1733, 2157], 'phospholipid': [1735], 'mass,': [1736], 'impaired': [1737, 1834, 1863, 1895], 'function,': [1739, 3048, 3444, 3635, 3741], 'fasting-induced': [1740], 'hemodynamic': [1744, 1776], 'dysfunction': [1745, 1777], '(37Mancuso': [1746], 'Lehman': [1752], 'J.J.': [1753], 'Sambandam': [1754], 'Green': [1764], 'Dramatic': [1768], 'triglycerides': [1771], 'precipitation': [1773], 'cardiac': [1775], 'during': [1778, 3512], 'brief': [1779], 'caloric': [1780], 'restriction': [1781], 'transgenic': [1783], 'myocardium': [1784], 'expressing': [1785], 'A2gamma.J.': [1789], '9216-9227Abstract': [1794], '(51)': [1802], 'Scholar).PLA2GVIB': [1804], '(41Bao': [1805, 1866], 'Miller': [1807, 1868], 'Ma': [1809, 1870], 'Z.': [1810, 1871], 'Wohltmann': [1811, 1872, 1921, 1973, 2026, 2116, 2168], 'Eng': [1813, 1874], 'Ramanadham': [1815, 1876], 'Moley': [1817, 1878], 'Turk': [1819, 1880, 1929, 1985, 2020, 2124, 2176], 'Male': [1821, 1882], 'do': [1824, 1885], 'express': [1826, 1887], 'VIA': [1828, 1889, 1996], 'produce': [1831, 1892], 'spermatozoa': [1832, 1893], 'motility': [1835, 1896], 'have': [1837, 1898, 2773, 3004], 'greatly': [1838, 1899], 'reduced': [1839, 1857, 1900], 'fertility.J.': [1840, 1901], '38194-38200Abstract': [1845, 1906], '(147)': [1853, 1914], 'Scholar)PNPLA9Global': [1855], 'male': [1858], 'fertility,': [1859], 'tolerance,': [1862], '44Bao': [1917], 'Jacobson': [1919, 2114, 2166], 'D.A.': [1920, 2115, 2167, 3467, 3764], 'Bohrer': [1923, 2118, 2170], 'Jin': [1925, 2120, 2172], 'Philipson': [1927, 2122, 2174], 'L.H.': [1928, 2123, 2175], 'Glucose': [1931, 2126, 2178], 'secretion,': [1934, 2129, 2181], 'islet': [1936, 2131, 2183], 'phospholipids': [1937, 2132, 2184], 'overexpress': [1941, 2136, 2188], 'iPLA2beta': [1942, 2137, 2189], 'pancreatic': [1944, 2139, 2191], 'beta-cells': [1945, 2140, 2192], 'iPLA2beta-null': [1948, 2143, 2195], 'mice.Am.': [1949, 2000, 2144, 2196], 'Physiol.': [1951, 2146, 2198, 3494, 3791], 'Metab.': [1953, 2148, 2200, 3496, 3688, 3793, 4027], '294:': [1955, 2150, 2202], 'E217-E229Crossref': [1956, 2151, 2203], '(55)': [1959, 2154, 2206], 'loss': [1963, 3887], 'mass': [1966], '(43Ramanadham': [1967], 'Yarasheski': [1969], 'K.E.': [1970], 'Silva': [1971], 'M.J.': [1972], 'Novack': [1975], 'D.V.': [1976], 'Christiansen': [1977], 'Tu': [1979], 'Lei': [1983], 'Age-related': [1987], 'changes': [1988], 'morphology': [1991], 'accelerated': [1993], '(iPLA2beta)-null': [1999], 'Pathol.': [2002, 2057], '172:': [2004, 2059], '868-881Abstract': [2005], '(49)': [2013], 'neurodegeneration': [2017], '(45Malik': [2018], 'I.': [2019], 'Montier': [2024], 'Wozniak': [2028], 'D.F.': [2029], 'Schmidt': [2030], 'R.E.': [2031], 'Kotzbauer': [2034, 2080], 'P.T.': [2035, 2081], 'Disrupted': [2036], 'homeostasis': [2038], 'ubiquitinated': [2042], 'model': [2047], 'infantile': [2049], 'neuroaxonal': [2050], 'dystrophy': [2051], 'caused': [2052, 3908], 'PLA2G6': [2054], 'mutations.Am.': [2055], '406-416Abstract': [2060], '(126)': [2068], 'Scholar).INAD': [2070], 'idiopathic': [2072], 'NBIA': [2073], '(46Gregory': [2074], 'Westaway': [2076], 'S.K.': [2077], 'Holm': [2078], 'I.E.': [2079], 'Hogarth': [2082], 'Sonek': [2084], 'Coryell': [2086], 'Nguyen': [2088], 'T.M.': [2089], 'Nardocci': [2090], 'Zorzi': [2092], 'Neurodegeneration': [2096], 'A(2).Neurology.': [2103], '71:': [2105], '1402-1409Crossref': [2106], '(209)': [2109], 'Scholar).iPLA2β': [2111], '(44Bao': [2112, 2164], 'Scholar)β-Cell-specific': [2156], 'Scholar).PLA2G6PLA2GVIA': [2208], 'Scholar)For': [2231], 'PNPLA1,': [2232, 2495], 'PNPLA4': [2233, 2496], '[GS2': [2234, 2497], '(28Lee': [2235, 2498], 'Salido': [2237, 2500], 'Yen': [2239, 2502], 'Isolation': [2241, 2504], 'new': [2244, 2492, 2507], 'GS2': [2246, 2509], '(DXS1283E)': [2247, 2510], 'CpG': [2250, 2513], 'island': [2251, 2514], 'between': [2252, 2515], 'STS': [2253, 2516], 'KAL1': [2255, 2518], 'Xp22.3.Genomics.': [2257, 2520], '1994;': [2258, 2521], '22:': [2259, 2522], '372-376Crossref': [2260, 2523], '(26)': [2263, 2526], 'iPLA2η': [2266, 2529], 'PLA2GVIF': [2315, 2578], 'Scholar)],': [2338, 2387, 2477, 2601, 2650, 2740], 'PNPLA5': [2339, 2602], '[GS2-like': [2340, 2603], '(4Lake': [2341, 2431, 2604, 2694, 2811, 3526], 'A.C.': [2342, 2432, 2605, 2695, 2812, 3527], 'Sun': [2343, 2433, 2606, 2696, 2813, 3528], 'J.L.': [2346, 2436, 2609, 2699, 2816, 3531], 'Revett': [2353, 2443, 2616, 2706, 2823, 3538], 'Shih': [2355, 2445, 2618, 2708, 2825, 3540], 'Liu': [2357, 2447, 2620, 2710, 2827, 3542], 'Paulsen': [2359, 2449, 2622, 2712, 2829, 3544], 'Expression,': [2363, 2453, 2626, 2716, 2833, 3548], 'regulation,': [2364, 2454, 2627, 2717, 2834, 3549, 3706], 'Adiponutrin': [2370, 2460, 2633, 2723, 2840, 3555], 'members.J.': [2372, 2462, 2635, 2725, 2842, 3557], 'Lipid': [2373, 2463, 2636, 2726, 2793, 2843, 3028, 3558], 'Res.': [2374, 2464, 2637, 2727, 2794, 2844, 3029, 3559], '2005;': [2375, 2465, 2638, 2728, 2845, 3560], '46:': [2376, 2466, 2639, 2729, 2846, 3561], '2477-2487Abstract': [2377, 2467, 2640, 2730, 2847, 3562], '(230)': [2385, 2475, 2648, 2738, 2855, 3570], 'PNPLA7': [2389, 2652], '[NRE': [2390, 2653], '(35Kienesberger': [2391, 2654], 'P.C.': [2392, 2655, 3010], 'Wolinski': [2395, 2658], 'K.Preiss-Landl,': [2396, 2659], 'Kohlwein': [2398, 2661], 'S.D.': [2399, 2662, 2779], 'insulin-regulated': [2407, 2670], 'lysophospholipase': [2408, 2671], 'homology': [2410, 2673], 'esterase.J.': [2414, 2677], '283:': [2418, 2681], '5908-5917Abstract': [2419, 2682], '(48)': [2427, 2690], 'NTE-like': [2430, 2693], 'no': [2478, 2741, 2752], 'lines': [2481, 2744], 'or': [2482, 2745, 2761, 3521, 3895], 'known.': [2487, 2750], 'Open': [2488], 'table': [2489], 'tab': [2493], 'For': [2494], 'Essentially,': [2751], 'published': [2753], 'data': [2754], 'exist': [2755], 'enzymatic': [2759], 'activity,': [2760], 'relevance': [2763], 'PNPLA1.': [2765], 'Low': [2766], 'tissues': [2772, 3879], 'been': [2774, 3005], '(3Wilson': [2776], 'P.A.': [2777], 'Gardner': [2778], 'Lambie': [2780], 'N.M.': [2781], 'Commans': [2782], 'S.A.': [2783], 'Crowther': [2784], 'family.J.': [2792], '47:': [2796], '1940-1949Abstract': [2797], 'Scholar)': [2807, 3849], 'consistently': [2810], 'Three': [2858], 'groups': [2859], 'independently': [2860], 'PNPLA2': [2862], '6Jenkins': [2910], '7Zimmermann': [2958, 3163, 3389], 'findings': [3000], 'reviewed': [3006], '(8Zechner': [3007], 'Kienesberger': [3009, 3663, 4002], 'Adipose': [3017, 3441, 3632, 3671, 3738, 4010], 'lipolytic': [3022], 'catabolism': [3023], 'cellular': [3025, 3100, 3676, 4015], 'fat': [3026, 3677, 4016], 'stores.J': [3027], '2009;': [3030], '50:': [3031], '3-21Abstract': [3032], '(403)': [3040], 'accordance': [3044], 'predominant': [3047], 'we': [3049], 'named': [3050, 3975], '(ATGL)': [3056], 'localizes': [3098], 'droplets': [3102, 4083], 'initial': [3106], 'step': [3107], 'hydrolysis,': [3110], 'yielding': [3111], 'diacylglycerols': [3112], 'Notably,': [3203], 'also': [3205, 3974], 'A': [3210], '(PLA)2': [3211], 'vitro': [3214, 3852], '9Notari': [3263], 'significance': [3311], 'these': [3313], 'activities': [3314], 'vivo': [3316], 'unclear.': [3318], 'tissues.': [3325, 3863], 'highest': [3327], 'white': [3333], 'brown': [3335], '(WAT': [3338], 'BAT,': [3340, 3875], 'respectively)': [3341], '10Kershaw': [3429, 3620], 'E.E.': [3430, 3621, 3727], 'Hamm': [3431, 3622, 3728], 'J.K.': [3432, 3623, 3729], 'Verhagen': [3433, 3624, 3730], 'Peroni': [3435, 3626, 3732], 'O.': [3436, 3627, 3733], 'Katic': [3437, 3628, 3734], 'Flier': [3439, 3630, 3736], 'J.S.': [3440, 3631, 3737], 'lipase:': [3443, 3634, 3740], 'insulin,': [3447, 3638, 3744], 'comparison': [3449, 3640, 3746], 'adiponutrin.Diabetes.': [3451, 3642, 3748], '148-157Crossref': [3454, 3645, 3751], '(290)': [3457, 3648, 3754], '11Kim': [3460, 3757], 'J.Y.': [3461, 3758], 'Tillison': [3462, 3759], 'Lee': [3464, 3761], 'J.H.': [3465, 3762], 'Rearick': [3466, 3763], 'Smas': [3468, 3765], 'ATGL/PNPLA2': [3475, 3772], 'downregulated': [3477, 3711, 3774], 'TNF-alpha': [3481, 3778], '3T3–L1': [3483, 3780, 4089], 'adipocytes': [3484, 3781], 'transactivation': [3490, 3787], 'PPARgamma.Am.': [3492, 3789], '291:': [3498, 3795], 'E115-E127Crossref': [3499, 3796], '(153)': [3502, 3799], 'Upregulation': [3505], 'transcript': [3508], 'differentiation': [3514], 'upon': [3518], 'dexamethasone': [3519], 'treatment': [3520], 'WAT': [3525, 3718], '5Villena': [3573], '12Lass': [3651], 'Schweiger': [3661, 4000], 'lipase-mediated': [3673, 4012], 'stores': [3678, 4017], 'activated': [3680, 4019], 'CGI-58': [3682, 4021], 'Chanarin-Dorfman': [3686, 4025], 'Syndrome.Cell': [3687, 4026], '3:': [3690, 4029], '309-319Abstract': [3691, 4030], '(673)': [3699, 4038], 'Consistent': [3702], 'nutritional': [3705], 'and,': [3714], 'conversely,': [3715], 'abrogated': [3723], 'action': [3725], '(10Kershaw': [3726], 'ATGL-knockout': [3805], '(-ko)': [3806], 'confirmed': [3850], 'indications': [3853], 'Impaired': [3864, 3921], 'resulted': [3868, 3928], 'deposition': [3872], 'WAT,': [3874], 'numerous': [3877], 'nonadipose': [3878], 'ATGL-ko': [3881, 3919, 3926, 3942], 'mice,': [3882], 'thereby': [3883], 'demonstrating': [3884], 'compensated': [3890], 'hormone-sensitive': [3892], '(HSL)': [3894], 'other': [3896], 'was': [3900, 3962, 4052], 'pronounced': [3902], '(>20-fold)': [3906], 'congestive': [3911], 'animals.': [3920], 'BAT': [3924], 'adaptation.': [3932], 'Despite': [3933], 'massive': [3934], 'shifted': [3944], 'toward': [3945], 'utilization': [3948], 'whole-body': [3952], 'sensitivity': [3954], 'tolerance.': [3957], 'An': [3958], 'activator': [3959], 'soon': [3964], 'after': [3965], 'identification': [3967], 'ATGL.': [3969], 'Comparative': [3970], 'identification-58': [3972], '(CGI-58),': [3973], 'containing-5': [3979], '(ABHD5),': [3980], 'drastically': [3981], 'enhances': [3982], 'ATGL-mediated': [3983], 'without': [3986], 'affecting': [3987], 'HSL': [3988], '(12Lass': [3990], 'mechanism': [4043], 'underlying': [4044], 'activation': [4046], 'currently': [4048], 'unknown.': [4049], 'However,': [4050], 'it': [4051], 'shown': [4053], 'hormonally': [4056], 'unstimulated': [4057], 'cells,': [4058], 'CGI-58/ABHD5': [4059, 4115], 'binds': [4060], 'perilipin,': [4062, 4112], 'droplet': [4066], '(14Brasaemle': [4068], 'Dolios': [4070], 'Shapiro': [4072], 'Wang': [4074], 'Proteomic': [4076], 'analysis': [4077], 'basal': [4085], 'lipolytically': [4087], 'stimulated': [4088], 'adipocytes.J.': [4090], '46835-46842Abstract': [4095], '(628)': [4103], 'Upon': [4106], 'hormonal': [4107], 'stimulation,': [4108], 'kinase-A': [4110], 'phosphorylates': [4111], 'dissociation': [4116], 'followed': [4117]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2095050768', 'counts_by_year': [{'year': 2024, 'cited_by_count': 17}, {'year': 2023, 'cited_by_count': 22}, {'year': 2022, 'cited_by_count': 19}, {'year': 2021, 'cited_by_count': 18}, {'year': 2020, 'cited_by_count': 23}, {'year': 2019, 'cited_by_count': 18}, {'year': 2018, 'cited_by_count': 15}, {'year': 2017, 'cited_by_count': 30}, {'year': 2016, 'cited_by_count': 16}, {'year': 2015, 'cited_by_count': 19}, {'year': 2014, 'cited_by_count': 10}, {'year': 2013, 'cited_by_count': 18}, {'year': 2012, 'cited_by_count': 37}], 'updated_date': '2025-01-07T02:21:58.043782', 'created_date': '2016-06-24'}