Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2094917447', 'doi': 'https://doi.org/10.1016/j.exppara.2006.01.003', 'title': 'Leishmania major: Low infection dose causes short-lived hyperalgesia and cytokines upregulation in mice', 'display_name': 'Leishmania major: Low infection dose causes short-lived hyperalgesia and cytokines upregulation in mice', 'publication_year': 2006, 'publication_date': '2006-03-04', 'ids': {'openalex': 'https://openalex.org/W2094917447', 'doi': 'https://doi.org/10.1016/j.exppara.2006.01.003', 'mag': '2094917447', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16516198'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.exppara.2006.01.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S102868315', 'display_name': 'Experimental Parasitology', 'issn_l': '0014-4894', 'issn': ['0014-4894', '1090-2449'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5101736084', 'display_name': 'Marc Karam', 'orcid': 'https://orcid.org/0000-0003-3897-8883'}, 'institutions': [{'id': 'https://openalex.org/I56306041', 'display_name': 'Lebanese American University', 'ror': 'https://ror.org/00hqkan37', 'country_code': 'LB', 'type': 'education', 'lineage': ['https://openalex.org/I56306041']}], 'countries': ['LB'], 'is_corresponding': False, 'raw_author_name': 'Marc Christophe Karam', 'raw_affiliation_strings': ['Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon', 'institution_ids': ['https://openalex.org/I56306041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5038110282', 'display_name': 'Hamdan Hamdan', 'orcid': 'https://orcid.org/0000-0002-2029-6772'}, 'institutions': [{'id': 'https://openalex.org/I56306041', 'display_name': 'Lebanese American University', 'ror': 'https://ror.org/00hqkan37', 'country_code': 'LB', 'type': 'education', 'lineage': ['https://openalex.org/I56306041']}], 'countries': ['LB'], 'is_corresponding': False, 'raw_author_name': 'Hamdan G. Hamdan', 'raw_affiliation_strings': ['Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon', 'institution_ids': ['https://openalex.org/I56306041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5031826131', 'display_name': 'Najib A. Abi Chedid', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I56306041', 'display_name': 'Lebanese American University', 'ror': 'https://ror.org/00hqkan37', 'country_code': 'LB', 'type': 'education', 'lineage': ['https://openalex.org/I56306041']}], 'countries': ['LB'], 'is_corresponding': False, 'raw_author_name': 'Najib A. Abi Chedid', 'raw_affiliation_strings': ['Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon', 'institution_ids': ['https://openalex.org/I56306041']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112305893', 'display_name': 'Kikki Bodman‐Smith', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I28290843', 'display_name': 'University of Surrey', 'ror': 'https://ror.org/00ks66431', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I28290843']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Kikki B. Bodman-Smith', 'raw_affiliation_strings': ['School of Biomedical and Molecular Sciences, University of Surrey, UK'], 'affiliations': [{'raw_affiliation_string': 'School of Biomedical and Molecular Sciences, University of Surrey, UK', 'institution_ids': ['https://openalex.org/I28290843']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5030456434', 'display_name': 'Lesley-Jane E. Eales-Reynolds', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I63072094', 'display_name': 'University of Portsmouth', 'ror': 'https://ror.org/03ykbk197', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I63072094']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'Lesley-Jane E. Eales-Reynolds', 'raw_affiliation_strings': ['Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, UK.'], 'affiliations': [{'raw_affiliation_string': 'Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, UK.', 'institution_ids': ['https://openalex.org/I63072094']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5002921784', 'display_name': 'George M. Baroody', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I56306041', 'display_name': 'Lebanese American University', 'ror': 'https://ror.org/00hqkan37', 'country_code': 'LB', 'type': 'education', 'lineage': ['https://openalex.org/I56306041']}], 'countries': ['LB'], 'is_corresponding': False, 'raw_author_name': 'George M. Baroody', 'raw_affiliation_strings': ['Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon'], 'affiliations': [{'raw_affiliation_string': 'Department of Biology, Faculty of Arts and Sciences, Lebanese American University, Byblos, Lebanon', 'institution_ids': ['https://openalex.org/I56306041']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3210, 'currency': 'USD', 'value_usd': 3210, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 0.328, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 19, 'citation_normalized_percentile': {'value': 0.885202, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 86, 'max': 87}, 'biblio': {'volume': '113', 'issue': '3', 'first_page': '168', 'last_page': '173'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10823', 'display_name': 'Research on Leishmaniasis Studies', 'score': 0.9998, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12817', 'display_name': 'Pharmacological Effects of Natural Compounds', 'score': 0.9914, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10890', 'display_name': 'Trypanosoma species research and implications', 'score': 0.9843, 'subfield': {'id': 'https://openalex.org/subfields/2713', 'display_name': 'Epidemiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [], 'concepts': [{'id': 'https://openalex.org/C2779245659', 'wikidata': 'https://www.wikidata.org/wiki/Q1633866', 'display_name': 'Hyperalgesia', 'level': 4, 'score': 0.86682}, {'id': 'https://openalex.org/C127561419', 'wikidata': 'https://www.wikidata.org/wiki/Q224527', 'display_name': 'Downregulation and upregulation', 'level': 3, 'score': 0.85026145}, {'id': 'https://openalex.org/C2780599195', 'wikidata': 'https://www.wikidata.org/wiki/Q1950715', 'display_name': 'Leishmania major', 'level': 4, 'score': 0.56776345}, {'id': 'https://openalex.org/C2778702967', 'wikidata': 'https://www.wikidata.org/wiki/Q2590966', 'display_name': 'Cutaneous leishmaniasis', 'level': 3, 'score': 0.55394506}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.5301032}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.48157978}, {'id': 'https://openalex.org/C74172505', 'wikidata': 'https://www.wikidata.org/wiki/Q194908', 'display_name': 'Interleukin', 'level': 3, 'score': 0.44774044}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.4174431}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.40285477}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.36746377}, {'id': 'https://openalex.org/C2781092759', 'wikidata': 'https://www.wikidata.org/wiki/Q524818', 'display_name': 'Leishmania', 'level': 3, 'score': 0.3577906}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.3332349}, {'id': 'https://openalex.org/C2776555147', 'wikidata': 'https://www.wikidata.org/wiki/Q331283', 'display_name': 'Leishmaniasis', 'level': 2, 'score': 0.28811607}, {'id': 'https://openalex.org/C71928629', 'wikidata': 'https://www.wikidata.org/wiki/Q804206', 'display_name': 'Parasite hosting', 'level': 2, 'score': 0.25698805}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.17458189}, {'id': 'https://openalex.org/C15490471', 'wikidata': 'https://www.wikidata.org/wiki/Q2734305', 'display_name': 'Nociception', 'level': 3, 'score': 0.11277592}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C136764020', 'wikidata': 'https://www.wikidata.org/wiki/Q466', 'display_name': 'World Wide Web', 'level': 1, 'score': 0.0}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D006930', 'descriptor_name': 'Hyperalgesia', 'qualifier_ui': 'Q000469', 'qualifier_name': 'parasitology', 'is_major_topic': True}, {'descriptor_ui': 'D007375', 'descriptor_name': 'Interleukin-1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018320', 'descriptor_name': 'Leishmania major', 'qualifier_ui': 'Q000472', 'qualifier_name': 'pathogenicity', 'is_major_topic': True}, {'descriptor_ui': 'D016773', 'descriptor_name': 'Leishmaniasis, Cutaneous', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006930', 'descriptor_name': 'Hyperalgesia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007375', 'descriptor_name': 'Interleukin-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015850', 'descriptor_name': 'Interleukin-6', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018320', 'descriptor_name': 'Leishmania major', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018320', 'descriptor_name': 'Leishmania major', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D016773', 'descriptor_name': 'Leishmaniasis, Cutaneous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016773', 'descriptor_name': 'Leishmaniasis, Cutaneous', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008807', 'descriptor_name': 'Mice, Inbred BALB C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015854', 'descriptor_name': 'Up-Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.exppara.2006.01.003', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S102868315', 'display_name': 'Experimental Parasitology', 'issn_l': '0014-4894', 'issn': ['0014-4894', '1090-2449'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16516198', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.82, 'display_name': 'Good health and well-being'}], 'grants': [{'funder': 'https://openalex.org/F4320311972', 'funder_display_name': 'Lebanese American University', 'award_id': None}], 'datasets': [], 'versions': [], 'referenced_works_count': 34, 'referenced_works': ['https://openalex.org/W1483961794', 'https://openalex.org/W1556108021', 'https://openalex.org/W1601816956', 'https://openalex.org/W1601925808', 'https://openalex.org/W1723158139', 'https://openalex.org/W1834954945', 'https://openalex.org/W1897226866', 'https://openalex.org/W1920075805', 'https://openalex.org/W1978515480', 'https://openalex.org/W1984632338', 'https://openalex.org/W1984915036', 'https://openalex.org/W2002299024', 'https://openalex.org/W2005060197', 'https://openalex.org/W2017779303', 'https://openalex.org/W2025474689', 'https://openalex.org/W2035041649', 'https://openalex.org/W204546040', 'https://openalex.org/W2054945050', 'https://openalex.org/W2061972338', 'https://openalex.org/W2065010653', 'https://openalex.org/W2067937458', 'https://openalex.org/W2075016546', 'https://openalex.org/W2075942059', 'https://openalex.org/W2078044345', 'https://openalex.org/W2087454739', 'https://openalex.org/W2135745523', 'https://openalex.org/W2150763544', 'https://openalex.org/W2155070012', 'https://openalex.org/W2166053693', 'https://openalex.org/W2168416755', 'https://openalex.org/W2168772220', 'https://openalex.org/W2168930459', 'https://openalex.org/W2261395449', 'https://openalex.org/W641588968'], 'related_works': ['https://openalex.org/W3186663621', 'https://openalex.org/W3165356626', 'https://openalex.org/W2300372494', 'https://openalex.org/W2142624029', 'https://openalex.org/W2120509159', 'https://openalex.org/W2094917447', 'https://openalex.org/W2090435595', 'https://openalex.org/W2065608771', 'https://openalex.org/W1997570781', 'https://openalex.org/W1569522228'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2094917447', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-11T05:58:30.098451', 'created_date': '2016-06-24'}