Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2094673317', 'doi': 'https://doi.org/10.1136/adc.64.8.1126', 'title': 'Prevalence of atopy and range of bronchial response to methacholine in 7 and 11 year old schoolchildren.', 'display_name': 'Prevalence of atopy and range of bronchial response to methacholine in 7 and 11 year old schoolchildren.', 'publication_year': 1989, 'publication_date': '1989-08-01', 'ids': {'openalex': 'https://openalex.org/W2094673317', 'doi': 'https://doi.org/10.1136/adc.64.8.1126', 'mag': '2094673317', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2675772', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1792516'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/adc.64.8.1126', 'pdf_url': 'https://adc.bmj.com/content/archdischild/64/8/1126.full.pdf', 'source': {'id': 'https://openalex.org/S207294652', 'display_name': 'Archives of Disease in Childhood', 'issn_l': '0003-9888', 'issn': ['0003-9888', '1468-2044'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://adc.bmj.com/content/archdischild/64/8/1126.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5000424698', 'display_name': 'R D Clifford', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43439940', 'display_name': 'University of Southampton', 'ror': 'https://ror.org/01ryk1543', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I43439940']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'R D Clifford', 'raw_affiliation_strings': ['Department of Medicine, University of Southampton.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Southampton.', 'institution_ids': ['https://openalex.org/I43439940']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111907326', 'display_name': 'M Radford', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43439940', 'display_name': 'University of Southampton', 'ror': 'https://ror.org/01ryk1543', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I43439940']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'M Radford', 'raw_affiliation_strings': ['Department of Medicine, University of Southampton.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Southampton.', 'institution_ids': ['https://openalex.org/I43439940']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027255387', 'display_name': 'J. B. L. Howell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43439940', 'display_name': 'University of Southampton', 'ror': 'https://ror.org/01ryk1543', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I43439940']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'J B Howell', 'raw_affiliation_strings': ['Department of Medicine, University of Southampton.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Southampton.', 'institution_ids': ['https://openalex.org/I43439940']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110451873', 'display_name': 'S.T. Holgate', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I43439940', 'display_name': 'University of Southampton', 'ror': 'https://ror.org/01ryk1543', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I43439940']}], 'countries': ['GB'], 'is_corresponding': False, 'raw_author_name': 'S T Holgate', 'raw_affiliation_strings': ['Department of Medicine, University of Southampton.'], 'affiliations': [{'raw_affiliation_string': 'Department of Medicine, University of Southampton.', 'institution_ids': ['https://openalex.org/I43439940']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 9.571, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 66, 'citation_normalized_percentile': {'value': 0.870034, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '64', 'issue': '8', 'first_page': '1126', 'last_page': '1132'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12547', 'display_name': 'Pharmaceutical studies and practices', 'score': 0.9526, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12547', 'display_name': 'Pharmaceutical studies and practices', 'score': 0.9526, 'subfield': {'id': 'https://openalex.org/subfields/2735', 'display_name': 'Pediatrics, Perinatology and Child Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T14333', 'display_name': 'Dermatoglyphics and Human Traits', 'score': 0.9241, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/methacholine', 'display_name': 'Methacholine', 'score': 0.95597374}, {'id': 'https://openalex.org/keywords/atopy', 'display_name': 'Atopy', 'score': 0.9326657}], 'concepts': [{'id': 'https://openalex.org/C2781260171', 'wikidata': 'https://www.wikidata.org/wiki/Q413188', 'display_name': 'Methacholine', 'level': 4, 'score': 0.95597374}, {'id': 'https://openalex.org/C2777697326', 'wikidata': 'https://www.wikidata.org/wiki/Q757678', 'display_name': 'Atopy', 'level': 3, 'score': 0.9326657}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.92494386}, {'id': 'https://openalex.org/C110586980', 'wikidata': 'https://www.wikidata.org/wiki/Q4168588', 'display_name': 'Provocation test', 'level': 3, 'score': 0.86200345}, {'id': 'https://openalex.org/C2776042228', 'wikidata': 'https://www.wikidata.org/wiki/Q35869', 'display_name': 'Asthma', 'level': 2, 'score': 0.7043321}, {'id': 'https://openalex.org/C44249647', 'wikidata': 'https://www.wikidata.org/wiki/Q208498', 'display_name': 'Confidence interval', 'level': 2, 'score': 0.59616524}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.3753473}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.26148742}, {'id': 'https://openalex.org/C2776178081', 'wikidata': 'https://www.wikidata.org/wiki/Q3286546', 'display_name': 'Respiratory disease', 'level': 3, 'score': 0.21059832}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.077786416}, {'id': 'https://openalex.org/C204787440', 'wikidata': 'https://www.wikidata.org/wiki/Q188504', 'display_name': 'Alternative medicine', 'level': 2, 'score': 0.0}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D001980', 'descriptor_name': 'Bronchi', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D001985', 'descriptor_name': 'Bronchial Provocation Tests', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D006969', 'descriptor_name': 'Hypersensitivity, Immediate', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D008688', 'descriptor_name': 'Methacholine Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D001980', 'descriptor_name': 'Bronchi', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001985', 'descriptor_name': 'Bronchial Provocation Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002648', 'descriptor_name': 'Child', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006969', 'descriptor_name': 'Hypersensitivity, Immediate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007428', 'descriptor_name': 'Intradermal Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016210', 'descriptor_name': 'Methacholine Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015203', 'descriptor_name': 'Reproducibility of Results', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012130', 'descriptor_name': 'Respiratory Hypersensitivity', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D012130', 'descriptor_name': 'Respiratory Hypersensitivity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/adc.64.8.1126', 'pdf_url': 'https://adc.bmj.com/content/archdischild/64/8/1126.full.pdf', 'source': {'id': 'https://openalex.org/S207294652', 'display_name': 'Archives of Disease in Childhood', 'issn_l': '0003-9888', 'issn': ['0003-9888', '1468-2044'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1792516', 'pdf_url': 'https://europepmc.org/articles/pmc1792516?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1792516', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2675772', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/adc.64.8.1126', 'pdf_url': 'https://adc.bmj.com/content/archdischild/64/8/1126.full.pdf', 'source': {'id': 'https://openalex.org/S207294652', 'display_name': 'Archives of Disease in Childhood', 'issn_l': '0003-9888', 'issn': ['0003-9888', '1468-2044'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'display_name': 'Good health and well-being', 'score': 0.64}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 21, 'referenced_works': ['https://openalex.org/W1974712643', 'https://openalex.org/W2001728531', 'https://openalex.org/W2004159775', 'https://openalex.org/W2004997090', 'https://openalex.org/W2011485068', 'https://openalex.org/W2070197559', 'https://openalex.org/W2080152482', 'https://openalex.org/W2090953328', 'https://openalex.org/W2106245415', 'https://openalex.org/W2116724543', 'https://openalex.org/W2133750711', 'https://openalex.org/W2135307447', 'https://openalex.org/W2137401824', 'https://openalex.org/W2139085537', 'https://openalex.org/W2155682897', 'https://openalex.org/W2157925125', 'https://openalex.org/W2164964161', 'https://openalex.org/W2167983016', 'https://openalex.org/W2411853700', 'https://openalex.org/W2444503541', 'https://openalex.org/W3216143596'], 'related_works': ['https://openalex.org/W2621169369', 'https://openalex.org/W2419064045', 'https://openalex.org/W2401225735', 'https://openalex.org/W2202739765', 'https://openalex.org/W2116724543', 'https://openalex.org/W2101196879', 'https://openalex.org/W2100110654', 'https://openalex.org/W2094673317', 'https://openalex.org/W2041564273', 'https://openalex.org/W190431057'], 'abstract_inverted_index': {'A': [0, 41, 135], 'sample': [1], 'of': [2, 20, 44, 77, 83, 89, 122, 151], '397': [3], 'from': [4, 38, 110, 125], '2503': [5], 'children': [6], 'aged': [7], '7': [8, 113, 128], 'and': [9, 31, 146], '11': [10, 118, 133], 'years,': [11], 'who': [12], 'took': [13], 'part': [14], 'in': [15, 23, 72, 79, 91, 96], 'an': [16], 'earlier': [17], 'questionnaire': [18], 'study': [19], 'respiratory': [21], 'symptoms': [22, 152], 'Southampton,': [24], 'was': [25, 46, 68, 101, 139, 149], 'chosen': [26], 'for': [27, 48], 'methacholine': [28, 67, 84, 145], 'bronchial': [29, 49, 142], 'provocation': [30, 50], 'allergen': [32], 'skin': [33], 'testing.': [34], 'Results': [35], 'were': [36], 'obtained': [37], '330': [39], '(84%).': [40], 'good': [42], 'level': [43], 'repeatability': [45], 'achieved': [47], 'testing': [51], 'giving': [52], 'a': [53, 87], '95%': [54], 'confidence': [55], 'interval': [56], 'equivalent': [57], 'to': [58, 106, 115, 130, 144], '1.74': [59], 'doubling': [60], 'concentrations.': [61, 74], 'The': [62, 75, 120], 'main': [63], 'problem': [64], 'encountered': [65], 'with': [66], 'its': [69], 'bitter': [70], 'taste': [71], 'high': [73], 'proportion': [76], 'children,': [78], 'whom': [80], 'the': [81, 92], 'dose': [82], 'which': [85, 148], 'produced': [86], 'fall': [88], '20%': [90], 'forced': [93], 'expiratory': [94], 'volume': [95], 'one': [97], 'second': [98], '(PD20': [99], 'methacholine)': [100], 'less': [102], 'than': [103], 'or': [104, 153], 'equal': [105], '6.4': [107], 'mumol,': [108], 'fell': [109], '29.1%': [111], 'at': [112, 117, 127, 132], 'years': [114, 129], '16.5%': [116], 'years.': [119, 134], 'prevalence': [121], 'atopy': [123], 'increased': [124], '26%': [126], '31.6%': [131], 'highly': [136], 'significant': [137], 'association': [138], 'found': [140], 'between': [141], 'responsiveness': [143], 'atopy,': [147], 'independent': [150], 'age': [154], 'group.': [155]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2094673317', 'counts_by_year': [{'year': 2015, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-14T03:11:17.880601', 'created_date': '2016-06-24'}