Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2094258167', 'doi': 'https://doi.org/10.1016/0091-6749(90)90216-q', 'title': 'Assessment of airway hyperresponsiveness in chronic stable asthma', 'display_name': 'Assessment of airway hyperresponsiveness in chronic stable asthma', 'publication_year': 1990, 'publication_date': '1990-01-01', 'ids': {'openalex': 'https://openalex.org/W2094258167', 'doi': 'https://doi.org/10.1016/0091-6749(90)90216-q', 'mag': '2094258167', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/2405041'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0091-6749(90)90216-q', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S108525051', 'display_name': 'Journal of Allergy and Clinical Immunology', 'issn_l': '0091-6749', 'issn': ['0091-6749', '1085-8725', '1097-6825'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5029076639', 'display_name': 'Susan A. Brooks', 'orcid': 'https://orcid.org/0000-0002-7908-7078'}, 'institutions': [{'id': 'https://openalex.org/I2613432', 'display_name': 'University of South Florida', 'ror': 'https://ror.org/032db5x82', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I2613432']}, {'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'S BROOKS', 'raw_affiliation_strings': ['College of Public Health, University of South Florida, Tampa, Fla.', 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'Supported by National Heart, Lung,'], 'affiliations': [{'raw_affiliation_string': 'College of Public Health, University of South Florida, Tampa, Fla.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Supported by National Heart, Lung,', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5063651696', 'display_name': 'Inge Bernstein', 'orcid': 'https://orcid.org/0000-0003-4095-432X'}, 'institutions': [{'id': 'https://openalex.org/I2613432', 'display_name': 'University of South Florida', 'ror': 'https://ror.org/032db5x82', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I2613432']}, {'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'I BERNSTEIN', 'raw_affiliation_strings': ['College of Public Health, University of South Florida, Tampa, Fla.', 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'Supported by National Heart, Lung,'], 'affiliations': [{'raw_affiliation_string': 'College of Public Health, University of South Florida, Tampa, Fla.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Supported by National Heart, Lung,', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058914412', 'display_name': 'P K Raghuprasad', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2613432', 'display_name': 'University of South Florida', 'ror': 'https://ror.org/032db5x82', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I2613432']}, {'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'P RAGHUPRASAD', 'raw_affiliation_strings': ['College of Public Health, University of South Florida, Tampa, Fla.', 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'Supported by National Heart, Lung,'], 'affiliations': [{'raw_affiliation_string': 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'institution_ids': ['https://openalex.org/I92156820']}, {'raw_affiliation_string': 'College of Public Health, University of South Florida, Tampa, Fla.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Supported by National Heart, Lung,', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5006746724', 'display_name': 'Clement Maccia', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2613432', 'display_name': 'University of South Florida', 'ror': 'https://ror.org/032db5x82', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I2613432']}, {'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'C MACCIA', 'raw_affiliation_strings': ['College of Public Health, University of South Florida, Tampa, Fla.', 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'Supported by National Heart, Lung,'], 'affiliations': [{'raw_affiliation_string': 'College of Public Health, University of South Florida, Tampa, Fla.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Supported by National Heart, Lung,', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'institution_ids': ['https://openalex.org/I92156820']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5071483991', 'display_name': 'L Mieczkowski', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2613432', 'display_name': 'University of South Florida', 'ror': 'https://ror.org/032db5x82', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I2613432']}, {'id': 'https://openalex.org/I92156820', 'display_name': 'University of Cincinnati Medical Center', 'ror': 'https://ror.org/02p72h367', 'country_code': 'US', 'type': 'healthcare', 'lineage': ['https://openalex.org/I92156820']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'L MIECZKOWSKI', 'raw_affiliation_strings': ['College of Public Health, University of South Florida, Tampa, Fla.', 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'Supported by National Heart, Lung,'], 'affiliations': [{'raw_affiliation_string': 'College of Public Health, University of South Florida, Tampa, Fla.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Supported by National Heart, Lung,', 'institution_ids': []}, {'raw_affiliation_string': 'Department of Environmental and Occupational Health, College of Public Health, University of South Florida, 13301 Bruce B. Downs Boulevard, MHH-104, Tampa, FL 33612.', 'institution_ids': ['https://openalex.org/I2613432']}, {'raw_affiliation_string': 'Departments of Environmental Health and Medicine, University of Cincinnati College of Medicine, Cincinnati, Ohio, and The Department of Environmental and Occupational Health,', 'institution_ids': ['https://openalex.org/I92156820']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4000, 'currency': 'USD', 'value_usd': 4000, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.304, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 70, 'citation_normalized_percentile': {'value': 0.953134, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 95, 'max': 96}, 'biblio': {'volume': '85', 'issue': '1', 'first_page': '17', 'last_page': '26'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10051', 'display_name': 'Asthma', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10051', 'display_name': 'Asthma', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12418', 'display_name': 'Diagnosis and Management of Chronic Cough', 'score': 0.986, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11651', 'display_name': 'Pulmonary Drug Delivery Techniques', 'score': 0.9731, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/methacholine', 'display_name': 'Methacholine', 'score': 0.9168693}, {'id': 'https://openalex.org/keywords/airway-hyperresponsiveness', 'display_name': 'Airway hyperresponsiveness', 'score': 0.64054495}, {'id': 'https://openalex.org/keywords/bronchial-hyperresponsiveness', 'display_name': 'Bronchial hyperresponsiveness', 'score': 0.6263273}, {'id': 'https://openalex.org/keywords/cough-reflex-sensitivity', 'display_name': 'Cough Reflex Sensitivity', 'score': 0.568492}, {'id': 'https://openalex.org/keywords/cough-hypersensitivity-syndrome', 'display_name': 'Cough Hypersensitivity Syndrome', 'score': 0.520551}, {'id': 'https://openalex.org/keywords/airway-afferent-nerves', 'display_name': 'Airway Afferent Nerves', 'score': 0.520168}, {'id': 'https://openalex.org/keywords/asthma', 'display_name': 'Asthma', 'score': 0.512678}], 'concepts': [{'id': 'https://openalex.org/C2781260171', 'wikidata': 'https://www.wikidata.org/wiki/Q413188', 'display_name': 'Methacholine', 'level': 4, 'score': 0.9168693}, {'id': 'https://openalex.org/C2776042228', 'wikidata': 'https://www.wikidata.org/wiki/Q35869', 'display_name': 'Asthma', 'level': 2, 'score': 0.8654767}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.82730913}, {'id': 'https://openalex.org/C105922876', 'wikidata': 'https://www.wikidata.org/wiki/Q1423981', 'display_name': 'Airway', 'level': 2, 'score': 0.69285816}, {'id': 'https://openalex.org/C3019828301', 'wikidata': 'https://www.wikidata.org/wiki/Q3801533', 'display_name': 'Airway hyperresponsiveness', 'level': 3, 'score': 0.64054495}, {'id': 'https://openalex.org/C2776238763', 'wikidata': 'https://www.wikidata.org/wiki/Q3801533', 'display_name': 'Bronchial hyperresponsiveness', 'level': 4, 'score': 0.6263273}, {'id': 'https://openalex.org/C2779134260', 'wikidata': 'https://www.wikidata.org/wiki/Q12136', 'display_name': 'Disease', 'level': 2, 'score': 0.45550278}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.43366337}, {'id': 'https://openalex.org/C2776178081', 'wikidata': 'https://www.wikidata.org/wiki/Q3286546', 'display_name': 'Respiratory disease', 'level': 3, 'score': 0.3982492}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.39791876}, {'id': 'https://openalex.org/C42219234', 'wikidata': 'https://www.wikidata.org/wiki/Q131130', 'display_name': 'Anesthesia', 'level': 1, 'score': 0.15651917}, {'id': 'https://openalex.org/C2777714996', 'wikidata': 'https://www.wikidata.org/wiki/Q7886', 'display_name': 'Lung', 'level': 2, 'score': 0.12933719}], 'mesh': [{'descriptor_ui': 'D000403', 'descriptor_name': 'Airway Resistance', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000403', 'descriptor_name': 'Airway Resistance', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D000403', 'descriptor_name': 'Airway Resistance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': 'Q000188', 'qualifier_name': 'drug therapy', 'is_major_topic': False}, {'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D001249', 'descriptor_name': 'Asthma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001985', 'descriptor_name': 'Bronchial Provocation Tests', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002908', 'descriptor_name': 'Chronic Disease', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007509', 'descriptor_name': 'Irritants', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': False}, {'descriptor_ui': 'D007509', 'descriptor_name': 'Irritants', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016210', 'descriptor_name': 'Methacholine Chloride', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008688', 'descriptor_name': 'Methacholine Compounds', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012720', 'descriptor_name': 'Severity of Illness Index', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011795', 'descriptor_name': 'Surveys and Questionnaires', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/0091-6749(90)90216-q', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S108525051', 'display_name': 'Journal of Allergy and Clinical Immunology', 'issn_l': '0091-6749', 'issn': ['0091-6749', '1085-8725', '1097-6825'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/2405041', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.74, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 48, 'referenced_works': ['https://openalex.org/W1538418766', 'https://openalex.org/W1810830498', 'https://openalex.org/W1849061480', 'https://openalex.org/W192372067', 'https://openalex.org/W1929520591', 'https://openalex.org/W1969772658', 'https://openalex.org/W1972370102', 'https://openalex.org/W1980484538', 'https://openalex.org/W1981313093', 'https://openalex.org/W1985174090', 'https://openalex.org/W1988745935', 'https://openalex.org/W1993532293', 'https://openalex.org/W2008319071', 'https://openalex.org/W2010887072', 'https://openalex.org/W2011746431', 'https://openalex.org/W2021795529', 'https://openalex.org/W2036824882', 'https://openalex.org/W2059608216', 'https://openalex.org/W2071754888', 'https://openalex.org/W2074252458', 'https://openalex.org/W2075990907', 'https://openalex.org/W2079936522', 'https://openalex.org/W2080152482', 'https://openalex.org/W2082728841', 'https://openalex.org/W2090337053', 'https://openalex.org/W2111757194', 'https://openalex.org/W2115405712', 'https://openalex.org/W2122820672', 'https://openalex.org/W2161153352', 'https://openalex.org/W2165264401', 'https://openalex.org/W2178519757', 'https://openalex.org/W2178556043', 'https://openalex.org/W2195369975', 'https://openalex.org/W2239962911', 'https://openalex.org/W2256535925', 'https://openalex.org/W2272759671', 'https://openalex.org/W2277523114', 'https://openalex.org/W2326720322', 'https://openalex.org/W2332176555', 'https://openalex.org/W2340002406', 'https://openalex.org/W2415187547', 'https://openalex.org/W2422436800', 'https://openalex.org/W2440240917', 'https://openalex.org/W2460206695', 'https://openalex.org/W2468355013', 'https://openalex.org/W2798643531', 'https://openalex.org/W4230897710', 'https://openalex.org/W630095732'], 'related_works': ['https://openalex.org/W85980459', 'https://openalex.org/W3145135515', 'https://openalex.org/W3030036346', 'https://openalex.org/W2391201281', 'https://openalex.org/W2152842148', 'https://openalex.org/W2131478017', 'https://openalex.org/W2045975158', 'https://openalex.org/W2030128601', 'https://openalex.org/W2021491313', 'https://openalex.org/W1793806683'], 'abstract_inverted_index': {'Airway': [0], 'reactivity': [1, 38], 'and': [2, 28, 58, 62, 78, 86, 88, 137, 160, 182, 192, 241, 244, 257], 'disease': [3, 21, 105, 183], 'severity': [4, 22, 184, 214], 'were': [5], 'investigated': [6], 'in': [7, 34, 71, 185, 213, 263], '24': [8], 'subjects': [9, 262], 'with': [10, 110, 120, 187], 'stable': [11, 189], 'chronic': [12, 188], 'bronchial': [13, 216], 'asthma.Disease': [14], 'sever@': [15], 'was': [16, 32, 149], 'determined': [17], 'by': [18], 'assigning': [19], 'a': [20, 49, 68, 151, 264], 'score': [23, 39], '(DSS)': [24], 'representing': [25], 'six': [26], 'clinical': [27, 176, 196], 'therapeutic': [29], 'parameters.Airway': [30], 'hyperresponsiveness': [31, 103, 181], 'assessed': [33], 'two': [35], 'ways:': [36], 'airway': [37, 102, 158, 180], '(ARS)': [40], 'based': [41], 'on': [42, 104], 'the': [43, 64, 98, 118, 122, 138, 155, 170, 173, 211, 248, 259], 'number': [44, 206], 'of': [45, 101, 140, 143, 157, 172, 175, 207, 215, 232, 261], 'positive': [46], 'responses': [47], 'to': [48, 53, 97, 210, 250], 'question': [50], 'concerning': [51], 'exposure': [52], '22': [54], 'nonspecific': [55], 'inhaled': [56], 'irritants': [57], 'me&a&line': [59], 'challenge': [60], 'testing': [61], 'determining': [63], 'cumulative': [65], 'dose': [66], 'causing': [67], '20%': [69], 'reduction': [70], 'FEVz': [72], '(CMD,,).A': [73], 'signijicant': [74], 'correlation': [75, 153], 'between': [76, 132, 154], 'DDS': [77], 'CMD,,': [79, 111, 136], '(r': [80, 112], '=': [81, 91, 113], '0.57;': [82], 'p': [83, 93], '<': [84, 94, 115], '0.003)': [85], 'DSS': [87, 161, 193], 'ARS': [89, 109, 123, 163, 191], '(c': [90], '0.67;': [92], '0.0003)': [95], 'attested': [96], 'important': [99], 'influence': [100], 'severity.Significant': [106], 'correlations': [107, 131], 'for': [108, 178, 198], '-0.60;p': [114], '0.002)': [116], 'suggested': [117], 'consistency': [119], 'which': [121], 'estimated': [124], 'methacholine': [125, 200], 'hyperresponsiveness.We': [126], 'found': [127], 'no': [128], 'statistically': [129], 'signiJicant': [130], 'DSS,': [133], 'ARS,': [134], 'or': [135, 145, 162, 223, 228], 'age': [139], 'subject,': [141], 'duration': [142], 'asthma,': [144, 217], 'other': [146], 'host': [147], 'characteristics.There': [148], 'not': [150], 'significant': [152], 'degree': [156], 'obstruction': [159], 'noted.The': [164], 'redts': [165], 'qf': [166], 'this': [167], 'investigation': [168], 'demonstrate': [169], 'value': [171], 'use': [174], 'information': [177], 'assessing': [179], 'patients': [186], 'asthma.Both': [190], 'are': [194], 'useful': [195], 'tools': [197], 'estimating': [199], 'reactivity.(J': [201], 'ALLERGY': [202], 'CLIN': [203], 'IMMUNOL': [204], '1990:85:17-26.)A': [205], 'factors': [208], 'contribute': [209], 'variability': [212], 'including': [218], 'viral': [219], 'respiratory': [220], 'infections,': [221], 'environmental': [222], 'occupational': [224], 'agents,': [225], 'allergens,': [226], 'psychologic': [227], 'emotional': [229], 'influences,': [230], 'adequacy': [231], 'drug': [233], 'treatment,': [234], 'physical': [235], 'stimuli,': [236], 'such': [237], 'as': [238], 'cold': [239], 'air,': [240], 'both': [242], 'particulate': [243], 'gaseous': [245], "irritants.'-'5In": [246], 'particular,': [247], 'sensitivity': [249], 'airborne': [251], 'irritant': [252], 'exposures': [253], 'has': [254], 'reported': [255], 'significance,': [256], 'therefore,': [258], 'identification': [260], 'screened': [265], 'population': [266], 'who': [267], 'have': [268]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2094258167', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 2}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 2}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-21T16:23:08.834431', 'created_date': '2016-06-24'}