Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2094206246', 'doi': 'https://doi.org/10.1093/oxfordjournals.molbev.a003872', 'title': 'Bayesian Selection of Continuous-Time Markov Chain Evolutionary Models', 'display_name': 'Bayesian Selection of Continuous-Time Markov Chain Evolutionary Models', 'publication_year': 2001, 'publication_date': '2001-06-01', 'ids': {'openalex': 'https://openalex.org/W2094206246', 'doi': 'https://doi.org/10.1093/oxfordjournals.molbev.a003872', 'mag': '2094206246', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11371589'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/oxfordjournals.molbev.a003872', 'pdf_url': 'https://academic.oup.com/mbe/article-pdf/18/6/1001/23448424/i0737-4038-018-06-1001.pdf', 'source': {'id': 'https://openalex.org/S57552105', 'display_name': 'Molecular Biology and Evolution', 'issn_l': '0737-4038', 'issn': ['0737-4038', '1537-1719'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://academic.oup.com/mbe/article-pdf/18/6/1001/23448424/i0737-4038-018-06-1001.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5039905606', 'display_name': 'Marc A. Suchard', 'orcid': 'https://orcid.org/0000-0001-9818-479X'}, 'institutions': [{'id': 'https://openalex.org/I161318765', 'display_name': 'University of California, Los Angeles', 'ror': 'https://ror.org/046rm7j60', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I161318765']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Marc A. Suchard', 'raw_affiliation_strings': ['Department of Biomathematics, UCLA School of Medicine, Los Angeles, CA 90095-7088, USA.'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomathematics, UCLA School of Medicine, Los Angeles, CA 90095-7088, USA.', 'institution_ids': ['https://openalex.org/I161318765']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5042766826', 'display_name': 'Robert E. Weiss', 'orcid': 'https://orcid.org/0000-0003-3648-8522'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Robert E. Weiss', 'raw_affiliation_strings': ['Department of Biomathematics, UCLA School of Medicine; †Department of Biostatistics, UCLA School of Public Health; and ‡Department of Human Genetics, UCLA School of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomathematics, UCLA School of Medicine; †Department of Biostatistics, UCLA School of Public Health; and ‡Department of Human Genetics, UCLA School of Medicine', 'institution_ids': []}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5013824247', 'display_name': 'Janet S. Sinsheimer', 'orcid': 'https://orcid.org/0000-0001-9540-5956'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Janet S. Sinsheimer', 'raw_affiliation_strings': ['Department of Biomathematics, UCLA School of Medicine; †Department of Biostatistics, UCLA School of Public Health; and ‡Department of Human Genetics, UCLA School of Medicine'], 'affiliations': [{'raw_affiliation_string': 'Department of Biomathematics, UCLA School of Medicine; †Department of Biostatistics, UCLA School of Public Health; and ‡Department of Human Genetics, UCLA School of Medicine', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3255, 'currency': 'USD', 'value_usd': 3255, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.098, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 815, 'citation_normalized_percentile': {'value': 0.999974, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '18', 'issue': '6', 'first_page': '1001', 'last_page': '1013'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10015', 'display_name': 'Genomics and Phylogenetic Studies', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10015', 'display_name': 'Genomics and Phylogenetic Studies', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10012', 'display_name': 'Genetic diversity and population structure', 'score': 0.9936, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11901', 'display_name': 'Bayesian Methods and Mixture Models', 'score': 0.9786, 'subfield': {'id': 'https://openalex.org/subfields/1702', 'display_name': 'Artificial Intelligence'}, 'field': {'id': 'https://openalex.org/fields/17', 'display_name': 'Computer Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/molecular-clock', 'display_name': 'Molecular clock', 'score': 0.67016846}, {'id': 'https://openalex.org/keywords/rate-of-evolution', 'display_name': 'Rate of evolution', 'score': 0.45339987}, {'id': 'https://openalex.org/keywords/molecular-evolution', 'display_name': 'Molecular evolution', 'score': 0.42540568}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.751625}, {'id': 'https://openalex.org/C196662502', 'wikidata': 'https://www.wikidata.org/wiki/Q827541', 'display_name': 'Molecular clock', 'level': 4, 'score': 0.67016846}, {'id': 'https://openalex.org/C207201462', 'wikidata': 'https://www.wikidata.org/wiki/Q182505', 'display_name': "Bayes' theorem", 'level': 3, 'score': 0.64825433}, {'id': 'https://openalex.org/C111350023', 'wikidata': 'https://www.wikidata.org/wiki/Q1191869', 'display_name': 'Markov chain Monte Carlo', 'level': 3, 'score': 0.6009968}, {'id': 'https://openalex.org/C98763669', 'wikidata': 'https://www.wikidata.org/wiki/Q176645', 'display_name': 'Markov chain', 'level': 2, 'score': 0.5602106}, {'id': 'https://openalex.org/C107673813', 'wikidata': 'https://www.wikidata.org/wiki/Q812534', 'display_name': 'Bayesian probability', 'level': 2, 'score': 0.53814566}, {'id': 'https://openalex.org/C78458016', 'wikidata': 'https://www.wikidata.org/wiki/Q840400', 'display_name': 'Evolutionary biology', 'level': 1, 'score': 0.5139251}, {'id': 'https://openalex.org/C2777949028', 'wikidata': 'https://www.wikidata.org/wiki/Q25303868', 'display_name': 'Rate of evolution', 'level': 4, 'score': 0.45339987}, {'id': 'https://openalex.org/C160234255', 'wikidata': 'https://www.wikidata.org/wiki/Q812535', 'display_name': 'Bayesian inference', 'level': 3, 'score': 0.4299246}, {'id': 'https://openalex.org/C166393388', 'wikidata': 'https://www.wikidata.org/wiki/Q856529', 'display_name': 'Molecular evolution', 'level': 4, 'score': 0.42540568}, {'id': 'https://openalex.org/C110121322', 'wikidata': 'https://www.wikidata.org/wiki/Q865811', 'display_name': 'Distribution (mathematics)', 'level': 2, 'score': 0.41955087}, {'id': 'https://openalex.org/C57830394', 'wikidata': 'https://www.wikidata.org/wiki/Q278079', 'display_name': 'Posterior probability', 'level': 3, 'score': 0.41560885}, {'id': 'https://openalex.org/C177769412', 'wikidata': 'https://www.wikidata.org/wiki/Q278090', 'display_name': 'Prior probability', 'level': 3, 'score': 0.41013205}, {'id': 'https://openalex.org/C121864883', 'wikidata': 'https://www.wikidata.org/wiki/Q677916', 'display_name': 'Statistical physics', 'level': 1, 'score': 0.38706818}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.37794933}, {'id': 'https://openalex.org/C90132467', 'wikidata': 'https://www.wikidata.org/wiki/Q171184', 'display_name': 'Phylogenetics', 'level': 3, 'score': 0.35642195}, {'id': 'https://openalex.org/C105795698', 'wikidata': 'https://www.wikidata.org/wiki/Q12483', 'display_name': 'Statistics', 'level': 1, 'score': 0.34332412}, {'id': 'https://openalex.org/C33923547', 'wikidata': 'https://www.wikidata.org/wiki/Q395', 'display_name': 'Mathematics', 'level': 0, 'score': 0.2757371}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.11917776}, {'id': 'https://openalex.org/C121332964', 'wikidata': 'https://www.wikidata.org/wiki/Q413', 'display_name': 'Physics', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C134306372', 'wikidata': 'https://www.wikidata.org/wiki/Q7754', 'display_name': 'Mathematical analysis', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D019143', 'descriptor_name': 'Evolution, Molecular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008957', 'descriptor_name': 'Models, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D012641', 'descriptor_name': 'Selection, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001499', 'descriptor_name': 'Bayes Theorem', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006678', 'descriptor_name': 'HIV', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D006678', 'descriptor_name': 'HIV', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008390', 'descriptor_name': 'Markov Chains', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010802', 'descriptor_name': 'Phylogeny', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011323', 'descriptor_name': 'Primates', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011323', 'descriptor_name': 'Primates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012336', 'descriptor_name': 'RNA, Ribosomal, 16S', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012336', 'descriptor_name': 'RNA, Ribosomal, 16S', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/oxfordjournals.molbev.a003872', 'pdf_url': 'https://academic.oup.com/mbe/article-pdf/18/6/1001/23448424/i0737-4038-018-06-1001.pdf', 'source': {'id': 'https://openalex.org/S57552105', 'display_name': 'Molecular Biology and Evolution', 'issn_l': '0737-4038', 'issn': ['0737-4038', '1537-1719'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11371589', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1093/oxfordjournals.molbev.a003872', 'pdf_url': 'https://academic.oup.com/mbe/article-pdf/18/6/1001/23448424/i0737-4038-018-06-1001.pdf', 'source': {'id': 'https://openalex.org/S57552105', 'display_name': 'Molecular Biology and Evolution', 'issn_l': '0737-4038', 'issn': ['0737-4038', '1537-1719'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311648', 'host_organization_name': 'Oxford University Press', 'host_organization_lineage': ['https://openalex.org/P4310311647', 'https://openalex.org/P4310311648'], 'host_organization_lineage_names': ['University of Oxford', 'Oxford University Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 60, 'referenced_works': ['https://openalex.org/W109881820', 'https://openalex.org/W125200397', 'https://openalex.org/W1525734744', 'https://openalex.org/W1561861607', 'https://openalex.org/W1586893832', 'https://openalex.org/W1595814035', 'https://openalex.org/W1800636980', 'https://openalex.org/W1874454247', 'https://openalex.org/W193795900', 'https://openalex.org/W1944637642', 'https://openalex.org/W1957469265', 'https://openalex.org/W1964187672', 'https://openalex.org/W1983002447', 'https://openalex.org/W2009068374', 'https://openalex.org/W2009570821', 'https://openalex.org/W2009596137', 'https://openalex.org/W2010814032', 'https://openalex.org/W2010981336', 'https://openalex.org/W2018881460', 'https://openalex.org/W2033947261', 'https://openalex.org/W2037764264', 'https://openalex.org/W2043887813', 'https://openalex.org/W2044819919', 'https://openalex.org/W2050913223', 'https://openalex.org/W2051296828', 'https://openalex.org/W2055840566', 'https://openalex.org/W2056760934', 'https://openalex.org/W2057293816', 'https://openalex.org/W2065461553', 'https://openalex.org/W2066152686', 'https://openalex.org/W2068117230', 'https://openalex.org/W2072329064', 'https://openalex.org/W2072419010', 'https://openalex.org/W2081450627', 'https://openalex.org/W2096916467', 'https://openalex.org/W2102424972', 'https://openalex.org/W2106706098', 'https://openalex.org/W2124061807', 'https://openalex.org/W2130416410', 'https://openalex.org/W2131145910', 'https://openalex.org/W2132947820', 'https://openalex.org/W2136064236', 'https://openalex.org/W2136796925', 'https://openalex.org/W2138309709', 'https://openalex.org/W2144775551', 'https://openalex.org/W2150783480', 'https://openalex.org/W2162250327', 'https://openalex.org/W2171319187', 'https://openalex.org/W2289404049', 'https://openalex.org/W2316582331', 'https://openalex.org/W2326073468', 'https://openalex.org/W2751862591', 'https://openalex.org/W4206702770', 'https://openalex.org/W4211177544', 'https://openalex.org/W4239160012', 'https://openalex.org/W4245668478', 'https://openalex.org/W4285719527', 'https://openalex.org/W4294554434', 'https://openalex.org/W4388320111', 'https://openalex.org/W603816015'], 'related_works': ['https://openalex.org/W2941366761', 'https://openalex.org/W2469219885', 'https://openalex.org/W2400047862', 'https://openalex.org/W2252767957', 'https://openalex.org/W2105762690', 'https://openalex.org/W2081450627', 'https://openalex.org/W2062220010', 'https://openalex.org/W2043469388', 'https://openalex.org/W2021610274', 'https://openalex.org/W2001967468'], 'abstract_inverted_index': {'We': [0, 75, 193], 'develop': [1], 'a': [2, 28, 87, 156, 227, 235], 'reversible': [3], 'jump': [4], 'Markov': [5], 'chain': [6], 'Monte': [7], 'Carlo': [8], 'approach': [9, 42], 'to': [10, 43], 'estimating': [11], 'the': [12, 37, 40, 55, 63, 70, 77, 84, 104, 122, 141, 152, 186, 196, 203], 'posterior': [13], 'distribution': [14, 159], 'of': [15, 39, 58, 65, 80, 86, 118, 190], 'phylogenies': [16], 'based': [17], 'on': [18], 'aligned': [19], 'DNA/RNA': [20], 'sequences': [21, 174], 'under': [22], 'several': [23], 'hierarchical': [24], 'evolutionary': [25], 'models.': [26], 'Using': [27], 'proper,': [29], 'yet': [30], 'nontruncated': [31], 'and': [32, 46, 68, 83, 101, 132, 144, 151, 160, 181, 185, 206, 226, 233], 'uninformative': [33], 'prior,': [34], 'we': [35, 168], 'demonstrate': [36], 'advantages': [38], 'Bayesian': [41], 'hypothesis': [44], 'testing': [45], 'estimation': [47], 'in': [48], 'phylogenetics': [49], 'by': [50, 99], 'comparing': [51], 'different': [52], 'models': [53, 82, 139], 'for': [54, 62, 69, 121, 129, 135, 212, 220, 241], 'infinitesimal': [56, 105], 'rates': [57, 150], 'change': [59, 106], 'among': [60, 72, 108, 230], 'nucleotides,': [61], 'number': [64], 'rate': [66, 127, 224], 'classes,': [67], 'relationships': [71], 'branch': [73], 'lengths.': [74], 'compare': [76], 'relative': [78], 'probabilities': [79, 107], 'these': [81], 'appropriateness': [85], 'molecular': [88, 228, 236], 'clock': [89, 229, 237], 'using': [90], 'Bayes': [91], 'factors.': [92], 'Our': [93], 'most': [94], 'general': [95], 'model,': [96], 'first': [97], 'proposed': [98], 'Tamura': [100], 'Nei,': [102], 'parameterizes': [103], 'nucleotides': [109], '(A,': [110], 'G,': [111], 'C,': [112], 'T/U)': [113], 'into': [114], 'six': [115], 'parameters,': [116], 'consisting': [117], 'three': [119], 'parameters': [120, 128], 'nucleotide': [123, 130, 136], 'stationary': [124, 158], 'distribution,': [125], 'two': [126], 'transitions,': [131], 'another': [133], 'parameter': [134], 'transversions.': [137], 'Nested': [138], 'include': [140], 'Hasegawa,': [142, 204], 'Kishino,': [143, 205], 'Yano': [145, 207], 'model': [146, 154, 198, 208], 'with': [147, 155], 'equal': [148, 161], 'transition': [149, 162], 'Kimura': [153, 197], 'uniform': [157], 'rates.': [163], 'To': [164], 'illustrate': [165], 'our': [166], 'methods,': [167], 'examine': [169], 'simulated': [170], 'data,': [171], '16S': [172], 'rRNA': [173], 'from': [175], '15': [176], 'contemporary': [177], 'eubacteria,': [178], 'halobacteria,': [179], 'eocytes,': [180], 'eukaryotes,': [182], '9': [183], 'primates,': [184], 'entire': [187], 'HIV': [188], 'genome': [189], '11': [191], 'isolates.': [192], 'find': [194], 'that': [195, 202, 216, 234], 'is': [199, 218], 'too': [200], 'restrictive,': [201], 'can': [209, 238], 'be': [210, 239], 'rejected': [211, 240], 'some': [213], 'data': [214], 'sets,': [215], 'there': [217], 'evidence': [219], 'more': [221, 242], 'than': [222], 'one': [223], 'class': [225], 'similar': [231], 'taxa,': [232], 'distantly': [243], 'related': [244], 'taxa.': [245]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2094206246', 'counts_by_year': [{'year': 2024, 'cited_by_count': 5}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 14}, {'year': 2021, 'cited_by_count': 26}, {'year': 2020, 'cited_by_count': 22}, {'year': 2019, 'cited_by_count': 38}, {'year': 2018, 'cited_by_count': 21}, {'year': 2017, 'cited_by_count': 31}, {'year': 2016, 'cited_by_count': 32}, {'year': 2015, 'cited_by_count': 59}, {'year': 2014, 'cited_by_count': 84}, {'year': 2013, 'cited_by_count': 62}, {'year': 2012, 'cited_by_count': 79}], 'updated_date': '2025-01-11T18:33:08.753758', 'created_date': '2016-06-24'}