Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2093265950', 'doi': 'https://doi.org/10.1126/science.183.4123.419', 'title': 'Inhibition of Cellular Mediated Immunity in Marihuana Smokers', 'display_name': 'Inhibition of Cellular Mediated Immunity in Marihuana Smokers', 'publication_year': 1974, 'publication_date': '1974-02-01', 'ids': {'openalex': 'https://openalex.org/W2093265950', 'doi': 'https://doi.org/10.1126/science.183.4123.419', 'mag': '2093265950', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/4271816'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.183.4123.419', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5078512850', 'display_name': 'Gabriel G. Nahas', 'orcid': 'https://orcid.org/0009-0005-9438-2517'}, 'institutions': [{'id': 'https://openalex.org/I78577930', 'display_name': 'Columbia University', 'ror': 'https://ror.org/00hj8s172', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I78577930']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Gabriel G. Nahas', 'raw_affiliation_strings': ['Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032'], 'affiliations': [{'raw_affiliation_string': 'Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032', 'institution_ids': ['https://openalex.org/I78577930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5026609346', 'display_name': 'Nicole Suciu‐Foca', 'orcid': 'https://orcid.org/0000-0001-5740-1399'}, 'institutions': [{'id': 'https://openalex.org/I78577930', 'display_name': 'Columbia University', 'ror': 'https://ror.org/00hj8s172', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I78577930']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Nicole Suciu-Foca', 'raw_affiliation_strings': ['Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032'], 'affiliations': [{'raw_affiliation_string': 'Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032', 'institution_ids': ['https://openalex.org/I78577930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5082689339', 'display_name': 'Jean‐Pierre Armand', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I78577930', 'display_name': 'Columbia University', 'ror': 'https://ror.org/00hj8s172', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I78577930']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Jean-Pierre Armand', 'raw_affiliation_strings': ['Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032'], 'affiliations': [{'raw_affiliation_string': 'Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032', 'institution_ids': ['https://openalex.org/I78577930']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5082170346', 'display_name': 'Akira Morishima', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I78577930', 'display_name': 'Columbia University', 'ror': 'https://ror.org/00hj8s172', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I78577930']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Akira Morishima', 'raw_affiliation_strings': ['Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032'], 'affiliations': [{'raw_affiliation_string': 'Departments of Anesthesiology, Surgery, and Pediatrics, College of Physicians & Surgeons of Columbia University, New York 10032', 'institution_ids': ['https://openalex.org/I78577930']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 11.026, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 235, 'citation_normalized_percentile': {'value': 0.995565, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 98, 'max': 99}, 'biblio': {'volume': '183', 'issue': '4123', 'first_page': '419', 'last_page': '420'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12477', 'display_name': 'Immunotoxin Therapy for Cancer Treatment', 'score': 0.9619, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12477', 'display_name': 'Immunotoxin Therapy for Cancer Treatment', 'score': 0.9619, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/cellular-immunity', 'display_name': 'Cellular immunity', 'score': 0.71125305}, {'id': 'https://openalex.org/keywords/cell-mediated-immunity', 'display_name': 'Cell mediated immunity', 'score': 0.6073041}], 'concepts': [{'id': 'https://openalex.org/C2779341262', 'wikidata': 'https://www.wikidata.org/wiki/Q182581', 'display_name': 'Immunity', 'level': 3, 'score': 0.80822575}, {'id': 'https://openalex.org/C3017875465', 'wikidata': 'https://www.wikidata.org/wiki/Q189146', 'display_name': 'Cellular immunity', 'level': 3, 'score': 0.71125305}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.6568451}, {'id': 'https://openalex.org/C3020653616', 'wikidata': 'https://www.wikidata.org/wiki/Q189146', 'display_name': 'Cell mediated immunity', 'level': 4, 'score': 0.6073041}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.58786315}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.45813894}, {'id': 'https://openalex.org/C64241487', 'wikidata': 'https://www.wikidata.org/wiki/Q5205774', 'display_name': 'DNA synthesis', 'level': 3, 'score': 0.42393097}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.41833207}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.33931175}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12232721}], 'mesh': [{'descriptor_ui': 'D002188', 'descriptor_name': 'Cannabis', 'qualifier_ui': 'Q000009', 'qualifier_name': 'adverse effects', 'is_major_topic': True}, {'descriptor_ui': 'D007111', 'descriptor_name': 'Immunity, Cellular', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D000293', 'descriptor_name': 'Adolescent', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002188', 'descriptor_name': 'Cannabis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004247', 'descriptor_name': 'DNA', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D003864', 'descriptor_name': 'Depression, Chemical', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007111', 'descriptor_name': 'Immunity, Cellular', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007165', 'descriptor_name': 'Immunosuppression Therapy', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D037102', 'descriptor_name': 'Lectins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008213', 'descriptor_name': 'Lymphocyte Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007959', 'descriptor_name': 'Lymphocyte Culture Test, Mixed', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009369', 'descriptor_name': 'Neoplasms', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D037121', 'descriptor_name': 'Plant Lectins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013936', 'descriptor_name': 'Thymidine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013936', 'descriptor_name': 'Thymidine', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014181', 'descriptor_name': 'Transplantation Immunology', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014316', 'descriptor_name': 'Tritium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014511', 'descriptor_name': 'Uremia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014511', 'descriptor_name': 'Uremia', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1126/science.183.4123.419', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S3880285', 'display_name': 'Science', 'issn_l': '0036-8075', 'issn': ['0036-8075', '1095-9203'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315823', 'host_organization_name': 'American Association for the Advancement of Science', 'host_organization_lineage': ['https://openalex.org/P4310315823'], 'host_organization_lineage_names': ['American Association for the Advancement of Science'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/4271816', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.85}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 14, 'referenced_works': ['https://openalex.org/W1966097032', 'https://openalex.org/W1987712862', 'https://openalex.org/W2001225304', 'https://openalex.org/W2007281803', 'https://openalex.org/W2054064036', 'https://openalex.org/W2056355453', 'https://openalex.org/W2065882804', 'https://openalex.org/W2079847011', 'https://openalex.org/W2085782671', 'https://openalex.org/W2108104378', 'https://openalex.org/W2332069959', 'https://openalex.org/W2412226729', 'https://openalex.org/W2414431316', 'https://openalex.org/W341404584'], 'related_works': ['https://openalex.org/W268599124', 'https://openalex.org/W2413735209', 'https://openalex.org/W2411445517', 'https://openalex.org/W2408612917', 'https://openalex.org/W2401020700', 'https://openalex.org/W2188187041', 'https://openalex.org/W2169816591', 'https://openalex.org/W2112819617', 'https://openalex.org/W2093265950', 'https://openalex.org/W2004631482'], 'abstract_inverted_index': {'The': [0], 'cellular': [1], 'mediated': [2], 'immunity': [3, 41], 'of': [4, 31, 36, 48, 56], '51': [5], 'young': [6], 'chronic': [7], 'marihuana': [8], 'smokers.': [9], 'as': [10], 'evaluated': [11], 'by': [12], 'the': [13], 'lymphocyte': [14], 'response': [15], 'in': [16, 33], 'vitro': [17], 'to': [18, 22, 29, 44, 53], 'allogeneic': [19], 'cells': [20], 'and': [21, 27], 'phytohemagglutinin,': [23], 'was': [24], 'significantly': [25], 'decreased': [26], 'similar': [28], 'that': [30], 'patients': [32], 'whom': [34], 'impairment': [35, 55], 'T': [37], '(thymus': [38], 'derived)': [39], 'cell': [40], 'is': [42], 'known': [43], 'occur.': [45], 'This': [46], 'inhibition': [47], 'blastogenesis': [49], 'might': [50], 'be': [51], 'related': [52], 'an': [54], 'DNA': [57], 'synthesis.': [58]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2093265950', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 3}, {'year': 2022, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 3}], 'updated_date': '2024-09-09T21:53:55.562167', 'created_date': '2016-06-24'}