Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2092711642', 'doi': 'https://doi.org/10.3324/haematol.2009.010702', 'title': 'Slow relapse in acute myeloid leukemia with inv(16) or t(16;16)', 'display_name': 'Slow relapse in acute myeloid leukemia with inv(16) or t(16;16)', 'publication_year': 2009, 'publication_date': '2009-07-16', 'ids': {'openalex': 'https://openalex.org/W2092711642', 'doi': 'https://doi.org/10.3324/haematol.2009.010702', 'mag': '2092711642', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/19608667', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2754969'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2009.010702', 'pdf_url': 'https://haematologica.org/article/download/5387/23937', 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://haematologica.org/article/download/5387/23937', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5057770699', 'display_name': 'Thomas Clozel', 'orcid': 'https://orcid.org/0000-0002-9781-8938'}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210124872', 'display_name': 'Hôpital Pontchaillou', 'ror': 'https://ror.org/02r25sw81', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124872', 'https://openalex.org/I4210155724']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'T. Clozel', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Inserm U522; IFR140; University of Rennes', 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}, {'raw_affiliation_string': 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France', 'institution_ids': ['https://openalex.org/I4210124872']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5059057760', 'display_name': 'Aline Renneville', 'orcid': 'https://orcid.org/0000-0003-0805-9640'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'A. Renneville', 'raw_affiliation_strings': [], 'affiliations': []}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5016132088', 'display_name': 'Marion Venot', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'M. Venot', 'raw_affiliation_strings': ['Inserm U522; IFR140; University of Rennes'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054745373', 'display_name': 'Claude Gardin', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'C. Gardin', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Molecular Genetic Department, Hospital;'], 'affiliations': [{'raw_affiliation_string': 'Molecular Genetic Department, Hospital;', 'institution_ids': []}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5041434167', 'display_name': 'Charicleia Kelaidi', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'C. Kelaidi', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Molecular Genetic Department, Hospital;'], 'affiliations': [{'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}, {'raw_affiliation_string': 'Molecular Genetic Department, Hospital;', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5058499860', 'display_name': 'Gaëlle Leroux', 'orcid': 'https://orcid.org/0000-0003-2729-4945'}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210124872', 'display_name': 'Hôpital Pontchaillou', 'ror': 'https://ror.org/02r25sw81', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124872', 'https://openalex.org/I4210155724']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'G. Leroux', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Inserm U522; IFR140; University of Rennes', 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}, {'raw_affiliation_string': 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France', 'institution_ids': ['https://openalex.org/I4210124872']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5027227964', 'display_name': 'Virginie Éclache', 'orcid': 'https://orcid.org/0000-0002-1085-4267'}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'V. Eclache', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Inserm U522; IFR140; University of Rennes'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5018416096', 'display_name': 'Claude Preudhomme', 'orcid': 'https://orcid.org/0000-0002-1267-9546'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'C. Preudhomme', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Molecular Genetic Department, Hospital;'], 'affiliations': [{'raw_affiliation_string': 'Molecular Genetic Department, Hospital;', 'institution_ids': []}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5014838075', 'display_name': 'Pierre Fenaux', 'orcid': 'https://orcid.org/0000-0002-0468-3553'}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}, {'id': 'https://openalex.org/I4210124872', 'display_name': 'Hôpital Pontchaillou', 'ror': 'https://ror.org/02r25sw81', 'country_code': 'FR', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210124872', 'https://openalex.org/I4210155724']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'P. Fenaux', 'raw_affiliation_strings': ['French National Centre for Rare Genetic Iron Overload Diseases, and', 'Inserm U522; IFR140; University of Rennes', 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}, {'raw_affiliation_string': 'French National Centre for Rare Genetic Iron Overload Diseases, and', 'institution_ids': []}, {'raw_affiliation_string': 'Liver Disease Department, University Hospital Pontchaillou, Rennes, France', 'institution_ids': ['https://openalex.org/I4210124872']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5007605254', 'display_name': 'Lionel Adès', 'orcid': 'https://orcid.org/0000-0002-9020-8766'}, 'institutions': [{'id': 'https://openalex.org/I56067802', 'display_name': 'Université de Rennes', 'ror': 'https://ror.org/015m7wh34', 'country_code': 'FR', 'type': 'education', 'lineage': ['https://openalex.org/I56067802']}, {'id': 'https://openalex.org/I154526488', 'display_name': 'Inserm', 'ror': 'https://ror.org/02vjkv261', 'country_code': 'FR', 'type': 'government', 'lineage': ['https://openalex.org/I154526488']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'L. Ades', 'raw_affiliation_strings': ['Inserm U522; IFR140; University of Rennes'], 'affiliations': [{'raw_affiliation_string': 'Inserm U522; IFR140; University of Rennes', 'institution_ids': ['https://openalex.org/I56067802', 'https://openalex.org/I154526488']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2000, 'currency': 'EUR', 'value_usd': 2157, 'provenance': 'doaj'}, 'apc_paid': {'value': 2000, 'currency': 'EUR', 'value_usd': 2157, 'provenance': 'doaj'}, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 8, 'citation_normalized_percentile': {'value': 0.744875, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 82, 'max': 83}, 'biblio': {'volume': '94', 'issue': '10', 'first_page': '1466', 'last_page': '1467'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10309', 'display_name': 'Acute Myeloid Leukemia Research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10950', 'display_name': 'Acute Lymphoblastic Leukemia research', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2739', 'display_name': 'Public Health, Environmental and Occupational Health'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11215', 'display_name': 'Chronic Myeloid Leukemia Treatments', 'score': 0.9959, 'subfield': {'id': 'https://openalex.org/subfields/2720', 'display_name': 'Hematology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/minimal-residual-disease', 'display_name': 'Minimal Residual Disease', 'score': 0.48996988}, {'id': 'https://openalex.org/keywords/fusion-transcript', 'display_name': 'Fusion transcript', 'score': 0.47389334}], 'concepts': [{'id': 'https://openalex.org/C2778041864', 'wikidata': 'https://www.wikidata.org/wiki/Q180983', 'display_name': 'Cytarabine', 'level': 3, 'score': 0.80713034}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.6262565}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.60607344}, {'id': 'https://openalex.org/C2778729363', 'wikidata': 'https://www.wikidata.org/wiki/Q11688946', 'display_name': 'Myeloid leukemia', 'level': 2, 'score': 0.5898661}, {'id': 'https://openalex.org/C2779823535', 'wikidata': 'https://www.wikidata.org/wiki/Q6865356', 'display_name': 'Minimal residual disease', 'level': 3, 'score': 0.48996988}, {'id': 'https://openalex.org/C143998085', 'wikidata': 'https://www.wikidata.org/wiki/Q162555', 'display_name': 'Oncology', 'level': 1, 'score': 0.47944656}, {'id': 'https://openalex.org/C2778274637', 'wikidata': 'https://www.wikidata.org/wiki/Q5510282', 'display_name': 'Fusion transcript', 'level': 4, 'score': 0.47389334}, {'id': 'https://openalex.org/C2776802502', 'wikidata': 'https://www.wikidata.org/wiki/Q417589', 'display_name': 'Anthracycline', 'level': 4, 'score': 0.4485579}, {'id': 'https://openalex.org/C111829193', 'wikidata': 'https://www.wikidata.org/wiki/Q1108970', 'display_name': 'Fusion gene', 'level': 3, 'score': 0.44848666}, {'id': 'https://openalex.org/C2778461978', 'wikidata': 'https://www.wikidata.org/wiki/Q29496', 'display_name': 'Leukemia', 'level': 2, 'score': 0.4401085}, {'id': 'https://openalex.org/C2776694085', 'wikidata': 'https://www.wikidata.org/wiki/Q974135', 'display_name': 'Chemotherapy', 'level': 2, 'score': 0.41577354}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.38263717}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.26443458}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25050253}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.104079515}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1039978}, {'id': 'https://openalex.org/C530470458', 'wikidata': 'https://www.wikidata.org/wiki/Q128581', 'display_name': 'Breast cancer', 'level': 3, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D015514', 'descriptor_name': 'Oncogene Proteins, Fusion', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015470', 'descriptor_name': 'Leukemia, Myeloid, Acute', 'qualifier_ui': 'Q000175', 'qualifier_name': 'diagnosis', 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015514', 'descriptor_name': 'Oncogene Proteins, Fusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012008', 'descriptor_name': 'Recurrence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013997', 'descriptor_name': 'Time Factors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014178', 'descriptor_name': 'Translocation, Genetic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D055815', 'descriptor_name': 'Young Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2009.010702', 'pdf_url': 'https://haematologica.org/article/download/5387/23937', 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2754969', 'pdf_url': 'https://europepmc.org/articles/pmc2754969?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2754969', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/19608667', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.3324/haematol.2009.010702', 'pdf_url': 'https://haematologica.org/article/download/5387/23937', 'source': {'id': 'https://openalex.org/S2752781272', 'display_name': 'Haematologica', 'issn_l': '0390-6078', 'issn': ['0390-6078', '1592-8721'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310317774', 'host_organization_name': 'Ferrata Storti Foundation', 'host_organization_lineage': ['https://openalex.org/P4310317774'], 'host_organization_lineage_names': ['Ferrata Storti Foundation'], 'type': 'journal'}, 'license': 'cc-by-nc', 'license_id': 'https://openalex.org/licenses/cc-by-nc', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.54}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 9, 'referenced_works': ['https://openalex.org/W1608690818', 'https://openalex.org/W1970740283', 'https://openalex.org/W2017389502', 'https://openalex.org/W2036862498', 'https://openalex.org/W2067072111', 'https://openalex.org/W2100663913', 'https://openalex.org/W2123081362', 'https://openalex.org/W2125549690', 'https://openalex.org/W2171122128'], 'related_works': ['https://openalex.org/W3118175352', 'https://openalex.org/W3028648349', 'https://openalex.org/W2911167977', 'https://openalex.org/W2900315325', 'https://openalex.org/W2561653224', 'https://openalex.org/W2172105256', 'https://openalex.org/W2055753086', 'https://openalex.org/W2010507532', 'https://openalex.org/W1978985807', 'https://openalex.org/W1501720035'], 'abstract_inverted_index': {'C282Y': [0], 'mutation': [1, 15, 64, 78, 101, 133, 192], 'in': [2, 79, 102, 107, 143, 176, 193], 'HFE': [3], 'with': [4, 89, 113, 146, 155, 169], 'an': [5, 90], 'extremely': [6, 66], 'severe': [7, 36], 'form': [8], 'of': [9, 38, 42, 52, 162, 165, 190], 'genetic': [10], 'hemochromatosis.We': [11], 'found': [12, 84], 'that': [13, 62, 85, 117, 179], 'this': [14, 63, 77, 191], 'may': [16], 'strongly': [17], 'affect': [18], 'the': [19, 35, 39, 56, 60, 105, 108, 129, 163, 166, 177, 187], 'hepcidin': [20, 109, 131], 'promoter': [21, 132], 'activity,': [22], 'especially': [23], 'by': [24], 'impairing': [25], 'its': [26], 'BMP/SMAD': [27], 'activation': [28], 'response,': [29], 'and': [30, 115, 138, 148], 'thus': [31], 'could': [32], 'contribute': [33], 'to': [34, 70, 104, 125], 'phenotype': [37], 'patient.The': [40], 'results': [41], 'Barton': [43, 114], 'et': [44], 'al.,': [45], '2': [46], 'obtained': [47], 'from': [48, 55, 118], 'a': [49, 73, 86, 99], 'large': [50, 74], 'panel': [51], 'patients': [53, 145], 'selected': [54, 144], 'HEIRS': [57], 'study,': [58], 'support': [59], 'fact': [61], 'is': [65, 122], 'rare,': [67], 'leading': [68], 'them': [69], 'not': [71, 94, 149, 174], 'recommend': [72], 'screening': [75, 141], 'for': [76, 128], 'hemochromatosis': [80], 'patients.In': [81], 'addition,': [82], 'they': [83], 'patient': [87, 178], 'presenting': [88], 'hyperferritinemia,': [91], 'which': [92, 172], 'was': [93, 173], 'confirmed': [95], 'thereafter,': [96], 'also': [97], 'has': [98], 'nc.-443C>T': [100], 'addition': [103], 'nc.-153C>T': [106, 130], 'promoter.We': [110], 'fully': [111, 150], 'agree': [112], 'collaborators,': [116], 'available': [119], 'data,': [120], 'there': [121], 'no': [123], 'need': [124], 'systematically': [126], 'search': [127], 'during': [134], 'population': [135], 'based': [136], 'studies': [137, 161], 'iron': [139, 152, 195], 'overload': [140, 153, 196], 'programs.However,': [142], 'proved': [147], 'explained': [151], 'phenotypes': [154], 'high': [156], 'plasma': [157], 'transferrin': [158], 'saturation,': [159], 'future': [160], 'presence': [164], 'nc.-153C>T,': [167], 'together': [168], 'family': [170], 'studies,': [171], 'possible': [175], 'we': [180], 'reported,': [181], 'should': [182], 'provide': [183], 'valuable': [184], 'information': [185], 'on': [186], 'clinical': [188], 'impact': [189], 'atypical': [194], 'conditions.': [197]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2092711642', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}], 'updated_date': '2024-12-08T20:53:49.761851', 'created_date': '2016-06-24'}