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'acid-responsive': [74], 'receptor.': [76], 'In': [77], 'both': [78, 125], 'element': [82], 'mammalian': [85], 'two-hybrid': [86], 'assays,': [87], 'found': [89], 'that': [90, 115, 142, 169], 'VDR-S278V': [91], 'is': [92, 143], 'activated': [93], 'but': [96, 106, 117], 'not': [97, 107, 118], 'whereas': [100], 'VDR-S237M': [101, 123], 'can': [102], 'respond': [103], 'LCA': [105, 128, 138], '1alpha,25(OH)2D3.': [109], 'Competitive': [110], 'binding': [112, 139], 'analysis': [113, 149], 'reveals': [114], '1alpha,25(OH)2D3,': [119], 'effectively': [120], 'binds': [121], 'bind': [129], 'VDR-S278V.': [131], 'We': [132], 'propose': [133], 'docking': [135], 'model': [136], 'supported': [144], 'mutagenesis': [146], 'data.': [147], 'Comparative': [148], 'of': [150, 163], 'the': [151, 161], 'VDR-LCA': [152], 'VDR-1alpha,25(OH)2D3': [154], 'structure-activity': [155], 'relationships': [156], 'should': [157], 'be': [158], 'useful': [159], 'in': [160, 174], 'development': [162], 'acid-derived': 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