Publication Information

{'id': 'https://openalex.org/W20921666', 'doi': 'https://doi.org/10.1042/bj2930151', 'title': 'Arginine is essential for the α-amylase inhibitory activity of the α-amylase/subtilisin inhibitor (BASI) from barley seeds', 'display_name': 'Arginine is essential for the α-amylase inhibitory activity of the α-amylase/subtilisin inhibitor (BASI) from barley seeds', 'publication_year': 1993, 'publication_date': '1993-07-01', 'ids': {'openalex': 'https://openalex.org/W20921666', 'doi': 'https://doi.org/10.1042/bj2930151', 'mag': '20921666', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8328958', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1134333'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj2930151', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://europepmc.org/articles/pmc1134333?pdf=render', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056647947', 'display_name': 'Jun‐ichi Abe', 'orcid': 'https://orcid.org/0000-0001-7439-7774'}, 'institutions': [{'id': 'https://openalex.org/I2800060819', 'display_name': 'Carlsberg Laboratory', 'ror': 'https://ror.org/055hfb865', 'country_code': 'DK', 'type': 'facility', 'lineage': ['https://openalex.org/I2800060819']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'J Abe', 'raw_affiliation_strings': ['Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Copenhagen Valby, Denmark'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500 Copenhagen Valby, Denmark', 'institution_ids': ['https://openalex.org/I2800060819']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5048547647', 'display_name': 'Ulrik Sidenius', 'orcid': 'https://orcid.org/0000-0002-6976-6181'}, 'institutions': [{'id': 'https://openalex.org/I2800060819', 'display_name': 'Carlsberg Laboratory', 'ror': 'https://ror.org/055hfb865', 'country_code': 'DK', 'type': 'facility', 'lineage': ['https://openalex.org/I2800060819']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'U Sidenius', 'raw_affiliation_strings': ['Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500, Copenhagen Valby, Denmark.'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500, Copenhagen Valby, Denmark.', 'institution_ids': ['https://openalex.org/I2800060819']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5067440189', 'display_name': 'Birte Svensson', 'orcid': 'https://orcid.org/0000-0002-2993-8196'}, 'institutions': [{'id': 'https://openalex.org/I2800060819', 'display_name': 'Carlsberg Laboratory', 'ror': 'https://ror.org/055hfb865', 'country_code': 'DK', 'type': 'facility', 'lineage': ['https://openalex.org/I2800060819']}], 'countries': ['DK'], 'is_corresponding': False, 'raw_author_name': 'B Svensson', 'raw_affiliation_strings': ['Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500, Copenhagen Valby, Denmark.'], 'affiliations': [{'raw_affiliation_string': 'Department of Chemistry, Carlsberg Laboratory, Gamle Carlsberg Vej 10, DK-2500, Copenhagen Valby, Denmark.', 'institution_ids': ['https://openalex.org/I2800060819']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.677, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 54, 'citation_normalized_percentile': {'value': 0.899155, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 93, 'max': 94}, 'biblio': {'volume': '293', 'issue': '1', 'first_page': '151', 'last_page': '155'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11617', 'display_name': 'Enzyme Production and Characterization', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1305', 'display_name': 'Biotechnology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T13725', 'display_name': 'Pineapple and bromelain studies', 'score': 0.9906, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12991', 'display_name': 'Phytase and its Applications', 'score': 0.9904, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/phenylglyoxal', 'display_name': 'Phenylglyoxal', 'score': 0.9957527}, {'id': 'https://openalex.org/keywords/subtilisin', 'display_name': 'Subtilisin', 'score': 0.730872}], 'concepts': [{'id': 'https://openalex.org/C2776661851', 'wikidata': 'https://www.wikidata.org/wiki/Q5934181', 'display_name': 'Phenylglyoxal', 'level': 4, 'score': 0.9957527}, {'id': 'https://openalex.org/C2779811187', 'wikidata': 'https://www.wikidata.org/wiki/Q423655', 'display_name': 'Subtilisin', 'level': 3, 'score': 0.730872}, {'id': 'https://openalex.org/C2777468819', 'wikidata': 'https://www.wikidata.org/wiki/Q173670', 'display_name': 'Arginine', 'level': 3, 'score': 0.68688035}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.6319701}, {'id': 'https://openalex.org/C2778460671', 'wikidata': 'https://www.wikidata.org/wiki/Q485277', 'display_name': 'Histidine', 'level': 3, 'score': 0.54318917}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.494308}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.46485817}, {'id': 'https://openalex.org/C71240020', 'wikidata': 'https://www.wikidata.org/wiki/Q186011', 'display_name': 'Stereochemistry', 'level': 1, 'score': 0.3593422}, {'id': 'https://openalex.org/C515207424', 'wikidata': 'https://www.wikidata.org/wiki/Q8066', 'display_name': 'Amino acid', 'level': 2, 'score': 0.29953825}], 'mesh': [{'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010658', 'descriptor_name': 'Phenylglyoxal', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D013381', 'descriptor_name': 'Subtilisins', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D000516', 'descriptor_name': 'alpha-Amylases', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D001120', 'descriptor_name': 'Arginine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D001426', 'descriptor_name': 'Bacterial Proteins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D002850', 'descriptor_name': 'Chromatography, Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001467', 'descriptor_name': 'Hordeum', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001467', 'descriptor_name': 'Hordeum', 'qualifier_ui': 'Q000201', 'qualifier_name': 'enzymology', 'is_major_topic': False}, {'descriptor_ui': 'D007700', 'descriptor_name': 'Kinetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010658', 'descriptor_name': 'Phenylglyoxal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013381', 'descriptor_name': 'Subtilisins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000516', 'descriptor_name': 'alpha-Amylases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1042/bj2930151', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S44425019', 'display_name': 'Biochemical Journal', 'issn_l': '0264-6021', 'issn': ['0264-6021', '1470-8728'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310311608', 'host_organization_name': 'Portland Press', 'host_organization_lineage': ['https://openalex.org/P4310311715', 'https://openalex.org/P4310311608'], 'host_organization_lineage_names': ['Biochemical Society', 'Portland Press'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1134333', 'pdf_url': 'https://europepmc.org/articles/pmc1134333?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1134333', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8328958', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1134333', 'pdf_url': 'https://europepmc.org/articles/pmc1134333?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Clean water and sanitation', 'id': 'https://metadata.un.org/sdg/6', 'score': 0.46}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 17, 'referenced_works': ['https://openalex.org/W105515906', 'https://openalex.org/W1551226986', 'https://openalex.org/W1974139665', 'https://openalex.org/W2007021393', 'https://openalex.org/W2031162503', 'https://openalex.org/W2041964108', 'https://openalex.org/W2053994489', 'https://openalex.org/W2084833184', 'https://openalex.org/W2087960090', 'https://openalex.org/W2090555186', 'https://openalex.org/W2104904241', 'https://openalex.org/W2117764873', 'https://openalex.org/W2312864587', 'https://openalex.org/W2328278900', 'https://openalex.org/W2397693771', 'https://openalex.org/W2410780908', 'https://openalex.org/W980785783'], 'related_works': ['https://openalex.org/W2467491856', 'https://openalex.org/W2327133413', 'https://openalex.org/W2054909748', 'https://openalex.org/W2044979688', 'https://openalex.org/W2044564993', 'https://openalex.org/W2029698716', 'https://openalex.org/W1975984439', 'https://openalex.org/W1538810654', 'https://openalex.org/W1530487393', 'https://openalex.org/W10851642'], 'abstract_inverted_index': {'Treatment': [0], 'of': [1, 42, 54, 68, 96, 116, 147, 161, 168], 'barley': [2, 35, 85], 'alpha-amylase/subtilisin': [3], 'inhibitor': [4, 171], '(BASI)': [5], 'with': [6, 65, 136, 144], 'reagents': [7], 'specific': [8], 'for': [9, 28], 'arginine,': [10], 'histidine,': [11], 'methionine': [12], 'and': [13, 16, 18, 60, 84, 110, 130], 'tyrosine': [14], 'residues': [15, 45, 109, 141], 'amino': [17], 'carboxyl': [19], 'groups': [20], 'indicates': [21], 'that': [22, 51], 'an': [23, 89], 'arginine': [24, 44, 108, 140], 'residue(s)': [25], 'is': [26, 61, 74, 99, 128], 'essential': [27], 'its': [29], 'action': [30], 'on': [31, 164], 'the': [32, 52, 70, 112, 123, 148, 165, 169], 'target': [33, 125], 'enzyme': [34], 'alpha-amylase': [36, 86, 105, 113], '2.': [37], 'Phenylglyoxal': [38], 'modified': [39], 'eight': [40], 'out': [41], '12': [43], 'in': [46, 155], 'BASI.': [47], 'Kinetic': [48], 'analysis': [49], 'shows': [50], 'inactivation': [53], 'BASI': [55, 83, 117, 121, 162], 'follows': [56], 'a': [57, 133, 158], 'pseudo-first-order': [58], 'reaction': [59, 64], 'due': [62], 'to': [63, 76, 132, 157], 'one': [66], 'molecule': [67], 'phenylglyoxal;': [69], 'second-order': [71], 'rate': [72], 'constant': [73], 'determined': [75], 'be': [77], '2.95': [78], 'M-1.min-1.': [79], 'At': [80], 'pH': [81], '8.0,': [82], '2': [87], 'form': [88], 'inactive': [90], '1:1': [91], 'complex.': [92], 'The': [93, 104], 'Ki': [94], 'value': [95], 'this': [97], 'association': [98], '2.2': [100], 'x': [101], '10(-10)': [102], 'M.': [103], 'protects': [106], 'four': [107, 138], 'also': [111], 'inhibitory': [114, 149], 'activity': [115], 'against': [118], 'phenylglyoxal.': [119], 'When': [120], 'from': [122, 172], 'phenylglyoxal-modified': [124], 'enzyme-inhibitor': [126], 'complex': [127], 'isolated': [129], 'subjected': [131], 'second': [134], 'treatment': [135], 'phenylglyoxal,': [137], 'additional': [139], 'are': [142, 153], 'modified,': [143], 'concomitant': [145], 'loss': [146], 'activity.': [150], 'These': [151], 'results': [152], 'discussed': [154], 'relation': [156], 'three-dimensional': [159], 'model': [160], 'based': [163], 'known': [166], 'structure': [167], 'corresponding': [170], 'wheat.': [173]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W20921666', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-16T09:12:21.507043', 'created_date': '2016-06-24'}