Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2091536187', 'doi': 'https://doi.org/10.1172/jci42440', 'title': 'A look at autoimmunity and inflammation in the eye', 'display_name': 'A look at autoimmunity and inflammation in the eye', 'publication_year': 2010, 'publication_date': '2010-09-01', 'ids': {'openalex': 'https://openalex.org/W2091536187', 'doi': 'https://doi.org/10.1172/jci42440', 'mag': '2091536187', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/20811163', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/2929721'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci42440', 'pdf_url': 'http://www.jci.org/articles/view/42440/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'http://www.jci.org/articles/view/42440/files/pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5004732672', 'display_name': 'Rachel R. Caspi', 'orcid': 'https://orcid.org/0000-0002-7140-7671'}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Rachel R. Caspi', 'raw_affiliation_strings': ['Laboratory of Immunology, National Eye Institute, NIH, Bethesda, Maryland 20892, USA.'], 'affiliations': [{'raw_affiliation_string': 'Laboratory of Immunology, National Eye Institute, NIH, Bethesda, Maryland 20892, USA.', 'institution_ids': ['https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5004732672'], 'corresponding_institution_ids': ['https://openalex.org/I1299303238'], 'apc_list': {'value': 5200, 'currency': 'USD', 'value_usd': 5200, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.082, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 421, 'citation_normalized_percentile': {'value': 0.995717, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '120', 'issue': '9', 'first_page': '3073', 'last_page': '3083'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11194', 'display_name': 'Ocular Diseases and Behçet’s Syndrome', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11194', 'display_name': 'Ocular Diseases and Behçet’s Syndrome', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11078', 'display_name': 'Inflammasome and immune disorders', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12599', 'display_name': 'Retinal and Optic Conditions', 'score': 0.9979, 'subfield': {'id': 'https://openalex.org/subfields/2731', 'display_name': 'Ophthalmology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/blinding', 'display_name': 'Blinding', 'score': 0.65977454}, {'id': 'https://openalex.org/keywords/pathogenesis', 'display_name': 'Pathogenesis', 'score': 0.6199637}], 'concepts': [{'id': 'https://openalex.org/C2780130043', 'wikidata': 'https://www.wikidata.org/wiki/Q192360', 'display_name': 'Autoimmunity', 'level': 3, 'score': 0.83002806}, {'id': 'https://openalex.org/C2776194053', 'wikidata': 'https://www.wikidata.org/wiki/Q280027', 'display_name': 'Uveitis', 'level': 2, 'score': 0.8171569}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.686175}, {'id': 'https://openalex.org/C2771230', 'wikidata': 'https://www.wikidata.org/wiki/Q4926699', 'display_name': 'Blinding', 'level': 3, 'score': 0.65977454}, {'id': 'https://openalex.org/C2776914184', 'wikidata': 'https://www.wikidata.org/wiki/Q101991', 'display_name': 'Inflammation', 'level': 2, 'score': 0.6207186}, {'id': 'https://openalex.org/C2780942790', 'wikidata': 'https://www.wikidata.org/wiki/Q372016', 'display_name': 'Pathogenesis', 'level': 2, 'score': 0.6199637}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.5685878}, {'id': 'https://openalex.org/C2780827179', 'wikidata': 'https://www.wikidata.org/wiki/Q422001', 'display_name': 'Retinal', 'level': 2, 'score': 0.48335975}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.24016288}, {'id': 'https://openalex.org/C142724271', 'wikidata': 'https://www.wikidata.org/wiki/Q7208', 'display_name': 'Pathology', 'level': 1, 'score': 0.17661831}, {'id': 'https://openalex.org/C118487528', 'wikidata': 'https://www.wikidata.org/wiki/Q161437', 'display_name': 'Ophthalmology', 'level': 1, 'score': 0.17338961}, {'id': 'https://openalex.org/C168563851', 'wikidata': 'https://www.wikidata.org/wiki/Q1436668', 'display_name': 'Randomized controlled trial', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D015551', 'descriptor_name': 'Autoimmunity', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015551', 'descriptor_name': 'Autoimmunity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004195', 'descriptor_name': 'Disease Models, Animal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': 'Q000033', 'qualifier_name': 'anatomy & histology', 'is_major_topic': False}, {'descriptor_ui': 'D005123', 'descriptor_name': 'Eye', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005544', 'descriptor_name': 'Forecasting', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008252', 'descriptor_name': 'Macaca fascicularis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008253', 'descriptor_name': 'Macaca mulatta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008819', 'descriptor_name': 'Mice, Nude', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008822', 'descriptor_name': 'Mice, Transgenic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011917', 'descriptor_name': 'Rats, Inbred Lew', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012160', 'descriptor_name': 'Retina', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D012160', 'descriptor_name': 'Retina', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D012160', 'descriptor_name': 'Retina', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014605', 'descriptor_name': 'Uveitis', 'qualifier_ui': 'Q000473', 'qualifier_name': 'pathology', 'is_major_topic': False}, {'descriptor_ui': 'D014605', 'descriptor_name': 'Uveitis', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D014605', 'descriptor_name': 'Uveitis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci42440', 'pdf_url': 'http://www.jci.org/articles/view/42440/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc2929721', 'pdf_url': 'https://europepmc.org/articles/pmc2929721?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2929721', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/20811163', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1172/jci42440', 'pdf_url': 'http://www.jci.org/articles/view/42440/files/pdf', 'source': {'id': 'https://openalex.org/S114430552', 'display_name': 'Journal of Clinical Investigation', 'issn_l': '0021-9738', 'issn': ['0021-9738', '1558-8238'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320279', 'host_organization_name': 'American Society for Clinical Investigation', 'host_organization_lineage': ['https://openalex.org/P4310320279'], 'host_organization_lineage_names': ['American Society for Clinical Investigation'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'id': 'https://metadata.un.org/sdg/3', 'score': 0.84, 'display_name': 'Good health and well-being'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 125, 'referenced_works': ['https://openalex.org/W1239992210', 'https://openalex.org/W1486960433', 'https://openalex.org/W1490664274', 'https://openalex.org/W1503222097', 'https://openalex.org/W1506397584', 'https://openalex.org/W1514234789', 'https://openalex.org/W1525096334', 'https://openalex.org/W1529539380', 'https://openalex.org/W1533466127', 'https://openalex.org/W1536518201', 'https://openalex.org/W1541564847', 'https://openalex.org/W1550450198', 'https://openalex.org/W1555480417', 'https://openalex.org/W1555764941', 'https://openalex.org/W1586034815', 'https://openalex.org/W1608267968', 'https://openalex.org/W1633194666', 'https://openalex.org/W1861321172', 'https://openalex.org/W1914308979', 'https://openalex.org/W1950453196', 'https://openalex.org/W1966161103', 'https://openalex.org/W1970080131', 'https://openalex.org/W1971097727', 'https://openalex.org/W1975810460', 'https://openalex.org/W1978227204', 'https://openalex.org/W1981651463', 'https://openalex.org/W1982263468', 'https://openalex.org/W1982476665', 'https://openalex.org/W1985073900', 'https://openalex.org/W1986015565', 'https://openalex.org/W1986561345', 'https://openalex.org/W1987984556', 'https://openalex.org/W1988368980', 'https://openalex.org/W1990592915', 'https://openalex.org/W1991527836', 'https://openalex.org/W1993293572', 'https://openalex.org/W1996610549', 'https://openalex.org/W2001830452', 'https://openalex.org/W2004318552', 'https://openalex.org/W2004633497', 'https://openalex.org/W2004858718', 'https://openalex.org/W2009171929', 'https://openalex.org/W2009846038', 'https://openalex.org/W201022256', 'https://openalex.org/W2010259403', 'https://openalex.org/W2014368646', 'https://openalex.org/W2016492948', 'https://openalex.org/W2019615790', 'https://openalex.org/W2019784292', 'https://openalex.org/W2021182590', 'https://openalex.org/W2025240311', 'https://openalex.org/W2026629764', 'https://openalex.org/W2029974988', 'https://openalex.org/W2031464548', 'https://openalex.org/W2032280256', 'https://openalex.org/W2037467064', 'https://openalex.org/W2038591447', 'https://openalex.org/W2039879526', 'https://openalex.org/W2042035086', 'https://openalex.org/W2044227082', 'https://openalex.org/W2044459638', 'https://openalex.org/W2052078062', 'https://openalex.org/W2052365715', 'https://openalex.org/W2054043426', 'https://openalex.org/W2054482011', 'https://openalex.org/W2055030159', 'https://openalex.org/W2058857268', 'https://openalex.org/W2060905466', 'https://openalex.org/W2061217789', 'https://openalex.org/W2062817085', 'https://openalex.org/W2067821114', 'https://openalex.org/W2071949189', 'https://openalex.org/W2079319457', 'https://openalex.org/W2079595796', 'https://openalex.org/W2086539844', 'https://openalex.org/W2088179039', 'https://openalex.org/W2088433266', 'https://openalex.org/W2089304180', 'https://openalex.org/W2089623210', 'https://openalex.org/W2090216336', 'https://openalex.org/W2095839372', 'https://openalex.org/W2096633753', 'https://openalex.org/W2099293177', 'https://openalex.org/W2103732467', 'https://openalex.org/W2104040734', 'https://openalex.org/W2105299620', 'https://openalex.org/W2109806505', 'https://openalex.org/W2112066442', 'https://openalex.org/W2112266897', 'https://openalex.org/W2115717665', 'https://openalex.org/W2116402118', 'https://openalex.org/W2117820020', 'https://openalex.org/W2119473653', 'https://openalex.org/W2120753117', 'https://openalex.org/W2121733174', 'https://openalex.org/W2122586908', 'https://openalex.org/W2129168778', 'https://openalex.org/W2130868516', 'https://openalex.org/W2132541143', 'https://openalex.org/W2135363829', 'https://openalex.org/W2136177420', 'https://openalex.org/W2139822623', 'https://openalex.org/W2141304647', 'https://openalex.org/W2141823625', 'https://openalex.org/W2142953619', 'https://openalex.org/W2145153016', 'https://openalex.org/W2145928191', 'https://openalex.org/W2152114275', 'https://openalex.org/W2154192717', 'https://openalex.org/W2155040781', 'https://openalex.org/W2158183837', 'https://openalex.org/W2164763018', 'https://openalex.org/W2165214298', 'https://openalex.org/W2236375555', 'https://openalex.org/W2346856253', 'https://openalex.org/W2400036872', 'https://openalex.org/W2411107612', 'https://openalex.org/W2419003374', 'https://openalex.org/W277472989', 'https://openalex.org/W4232229546', 'https://openalex.org/W4313335066', 'https://openalex.org/W4313347649', 'https://openalex.org/W560233946', 'https://openalex.org/W586800472', 'https://openalex.org/W62741965'], 'related_works': ['https://openalex.org/W4385587359', 'https://openalex.org/W4253335619', 'https://openalex.org/W3193329047', 'https://openalex.org/W3175462489', 'https://openalex.org/W2799289174', 'https://openalex.org/W2081859324', 'https://openalex.org/W2078668847', 'https://openalex.org/W2071654623', 'https://openalex.org/W2059459105', 'https://openalex.org/W1996966348'], 'abstract_inverted_index': {'Autoimmune': [0], 'and': [1, 20, 80], 'inflammatory': [2, 11], 'uveitis': [3, 79], 'are': [4, 21, 44, 81], 'a': [5, 16, 66], 'group': [6, 48], 'of': [7, 37, 40, 49, 57, 69, 78, 88], 'potentially': [8], 'blinding': [9], 'intraocular': [10], 'diseases': [12], 'that': [13], 'arise': [14], 'without': [15], 'known': [17], 'infectious': [18], 'trigger': [19], 'often': [22], 'associated': [23], 'with': [24], 'immunological': [25, 72], 'responses': [26], 'to': [27, 46], 'unique': [28], 'retinal': [29, 61], 'proteins.': [30], 'In': [31], 'the': [32, 38, 70, 76, 86], 'United': [33], 'States,': [34], 'about': [35, 65], '10%': [36], 'cases': [39], 'severe': [41], 'visual': [42], 'handicap': [43], 'attributed': [45], 'this': [47], 'disorders.': [50], 'As': [51], 'I': [52], 'discuss': [53], 'here,': [54], 'experimental': [55], 'models': [56], 'ocular': [58], 'autoimmunity': [59], 'targeting': [60], 'proteins': [62], 'have': [63], 'brought': [64], 'better': [67], 'understanding': [68], 'basic': [71], 'mechanisms': [73], 'involved': [74], 'in': [75], 'pathogenesis': [77], 'serving': [82], 'as': [83], 'templates': [84], 'for': [85], 'development': [87], 'novel': [89], 'therapies.': [90]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2091536187', 'counts_by_year': [{'year': 2024, 'cited_by_count': 27}, {'year': 2023, 'cited_by_count': 22}, {'year': 2022, 'cited_by_count': 41}, {'year': 2021, 'cited_by_count': 42}, {'year': 2020, 'cited_by_count': 29}, {'year': 2019, 'cited_by_count': 32}, {'year': 2018, 'cited_by_count': 26}, {'year': 2017, 'cited_by_count': 28}, {'year': 2016, 'cited_by_count': 28}, {'year': 2015, 'cited_by_count': 38}, {'year': 2014, 'cited_by_count': 24}, {'year': 2013, 'cited_by_count': 28}, {'year': 2012, 'cited_by_count': 24}], 'updated_date': '2025-01-11T19:31:15.036413', 'created_date': '2016-06-24'}