Title: HIGH FREQUENCY OF APOPTOSIS IN INFANTILE CAPILLARY HAEMANGIOMA
Abstract: The Journal of PathologyVolume 179, Issue 4 p. 403-408 Original Paper HIGH FREQUENCY OF APOPTOSIS IN INFANTILE CAPILLARY HAEMANGIOMA JUN IWATA, Corresponding Author JUN IWATA Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanDr Jun Iwata, Department of Pathology, Kochi Medical School, Kohasu, Okoh-cho, Nankoku, Kochi 783, JapanSearch for more papers by this authorHIROSHI SONOBE, HIROSHI SONOBE Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorMUTSUO FURIHATA, MUTSUO FURIHATA Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorEIJI IDO, EIJI IDO Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorYUJI OHTSUKI, YUJI OHTSUKI Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this author JUN IWATA, Corresponding Author JUN IWATA Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanDr Jun Iwata, Department of Pathology, Kochi Medical School, Kohasu, Okoh-cho, Nankoku, Kochi 783, JapanSearch for more papers by this authorHIROSHI SONOBE, HIROSHI SONOBE Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorMUTSUO FURIHATA, MUTSUO FURIHATA Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorEIJI IDO, EIJI IDO Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this authorYUJI OHTSUKI, YUJI OHTSUKI Department of Pathology, Kochi Medical School, Nankoku, Kochi 783, JapanSearch for more papers by this author First published: August 1996 https://doi.org/10.1002/(SICI)1096-9896(199608)179:4<403::AID-PATH604>3.0.CO;2-ECitations: 35AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Infantile capillary haemangioma (ICH) is a well-established clinicopathological entity which often regresses spontaneously. To elucidate the cause of spontaneous involution of ICH, the apoptotic and proliferative activities in seven cases of ICH were compared with those in five cases of lobular capillary haemangioma (LCH), using formalin-fixed paraffin-embedded tissue sections. The number of apoptotic cells detected by the modified in situ end-labelling method was significantly higher in ICH than in LCH, while the proliferative activities evaluated with mitosis and Ki-67 antigen expression did not differ significantly. Lewisy (Ley) antigen, an apoptosis-associated marker, was expressed in all cases of ICH but in none of LCH, while labelling for p53 protein and bcl-2 protein was almost completely negative in both tumours. These findings clearly demonstrate a much higher apoptotic activity in ICH than in LCH and suggest that apoptosis might be a cause of the spontaneous involution of ICH. Citing Literature Volume179, Issue4August 1996Pages 403-408 RelatedInformation
Publication Year: 1996
Publication Date: 1996-08-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 46
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