Publication Information

{'id': 'https://openalex.org/W2091182287', 'doi': 'https://doi.org/10.1136/gut.27.3.243', 'title': 'Mucus degradation by pepsin: comparison of mucolytic activity of human pepsin 1 and pepsin 3: implications in peptic ulceration.', 'display_name': 'Mucus degradation by pepsin: comparison of mucolytic activity of human pepsin 1 and pepsin 3: implications in peptic ulceration.', 'publication_year': 1986, 'publication_date': '1986-03-01', 'ids': {'openalex': 'https://openalex.org/W2091182287', 'doi': 'https://doi.org/10.1136/gut.27.3.243', 'mag': '2091182287', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/3084340', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1433406'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/gut.27.3.243', 'pdf_url': 'https://gut.bmj.com/content/27/3/243.full.pdf', 'source': {'id': 'https://openalex.org/S3251770', 'display_name': 'Gut', 'issn_l': '0017-5749', 'issn': ['0017-5749', '1468-3288'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://gut.bmj.com/content/27/3/243.full.pdf', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5040094511', 'display_name': 'Jeffrey P. Pearson', 'orcid': 'https://orcid.org/0000-0002-9816-7866'}, 'institutions': [{'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2802775644', 'display_name': 'Royal Liverpool University Hospital', 'ror': 'https://ror.org/01ycr6b80', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802729160', 'https://openalex.org/I2802775644']}, {'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}, {'id': 'https://openalex.org/I2800849109', 'display_name': 'Liverpool Hospital', 'ror': 'https://ror.org/03zzzks34', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800849109']}], 'countries': ['AU', 'GB'], 'is_corresponding': False, 'raw_author_name': 'J P Pearson', 'raw_affiliation_strings': ['Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'Royal Liverpool Hospital, Liverpool'], 'affiliations': [{'raw_affiliation_string': 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'institution_ids': ['https://openalex.org/I84884186']}, {'raw_affiliation_string': 'Royal Liverpool Hospital, Liverpool', 'institution_ids': ['https://openalex.org/I2802775644', 'https://openalex.org/I146655781', 'https://openalex.org/I2800849109']}, {'raw_affiliation_string': 'Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5062273267', 'display_name': 'Roberta J. Ward', 'orcid': 'https://orcid.org/0000-0002-5671-784X'}, 'institutions': [{'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2802775644', 'display_name': 'Royal Liverpool University Hospital', 'ror': 'https://ror.org/01ycr6b80', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802729160', 'https://openalex.org/I2802775644']}, {'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}, {'id': 'https://openalex.org/I2800849109', 'display_name': 'Liverpool Hospital', 'ror': 'https://ror.org/03zzzks34', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800849109']}], 'countries': ['AU', 'GB'], 'is_corresponding': False, 'raw_author_name': 'R Ward', 'raw_affiliation_strings': ['Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'Royal Liverpool Hospital, Liverpool'], 'affiliations': [{'raw_affiliation_string': 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'institution_ids': ['https://openalex.org/I84884186']}, {'raw_affiliation_string': 'Royal Liverpool Hospital, Liverpool', 'institution_ids': ['https://openalex.org/I2802775644', 'https://openalex.org/I146655781', 'https://openalex.org/I2800849109']}, {'raw_affiliation_string': 'Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5112100968', 'display_name': 'Adrian Allen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2800849109', 'display_name': 'Liverpool Hospital', 'ror': 'https://ror.org/03zzzks34', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800849109']}, {'id': 'https://openalex.org/I2802775644', 'display_name': 'Royal Liverpool University Hospital', 'ror': 'https://ror.org/01ycr6b80', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802729160', 'https://openalex.org/I2802775644']}, {'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['AU', 'GB'], 'is_corresponding': False, 'raw_author_name': 'A Allen', 'raw_affiliation_strings': ['Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'Royal Liverpool Hospital, Liverpool'], 'affiliations': [{'raw_affiliation_string': 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'institution_ids': ['https://openalex.org/I84884186']}, {'raw_affiliation_string': 'Royal Liverpool Hospital, Liverpool', 'institution_ids': ['https://openalex.org/I2800849109', 'https://openalex.org/I2802775644', 'https://openalex.org/I146655781']}, {'raw_affiliation_string': 'Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111804174', 'display_name': 'N B Roberts', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802775644', 'display_name': 'Royal Liverpool University Hospital', 'ror': 'https://ror.org/01ycr6b80', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802729160', 'https://openalex.org/I2802775644']}, {'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2800849109', 'display_name': 'Liverpool Hospital', 'ror': 'https://ror.org/03zzzks34', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800849109']}, {'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['AU', 'GB'], 'is_corresponding': False, 'raw_author_name': 'N B Roberts', 'raw_affiliation_strings': ['Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'Royal Liverpool Hospital, Liverpool'], 'affiliations': [{'raw_affiliation_string': 'Royal Liverpool Hospital, Liverpool', 'institution_ids': ['https://openalex.org/I2802775644', 'https://openalex.org/I2800849109', 'https://openalex.org/I146655781']}, {'raw_affiliation_string': 'Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'institution_ids': []}, {'raw_affiliation_string': 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'institution_ids': ['https://openalex.org/I84884186']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5110826063', 'display_name': 'W. H. Taylor', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I84884186', 'display_name': 'Newcastle University', 'ror': 'https://ror.org/01kj2bm70', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I84884186']}, {'id': 'https://openalex.org/I2800849109', 'display_name': 'Liverpool Hospital', 'ror': 'https://ror.org/03zzzks34', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800849109']}, {'id': 'https://openalex.org/I2802775644', 'display_name': 'Royal Liverpool University Hospital', 'ror': 'https://ror.org/01ycr6b80', 'country_code': 'GB', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2802729160', 'https://openalex.org/I2802775644']}, {'id': 'https://openalex.org/I146655781', 'display_name': 'University of Liverpool', 'ror': 'https://ror.org/04xs57h96', 'country_code': 'GB', 'type': 'education', 'lineage': ['https://openalex.org/I146655781']}], 'countries': ['AU', 'GB'], 'is_corresponding': False, 'raw_author_name': 'W H Taylor', 'raw_affiliation_strings': ['Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'Royal Liverpool Hospital, Liverpool'], 'affiliations': [{'raw_affiliation_string': 'From the Department ofPhysiological Sciences, University ofNewcastle upon Tyne, Newcastle upon Tyne, and Department of Chemical Pathology and Metabolic Medicine,', 'institution_ids': ['https://openalex.org/I84884186']}, {'raw_affiliation_string': 'Royal Liverpool Hospital, Liverpool', 'institution_ids': ['https://openalex.org/I2800849109', 'https://openalex.org/I2802775644', 'https://openalex.org/I146655781']}, {'raw_affiliation_string': 'Department of Physiological Sciences, Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH.', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 12.024, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 97, 'citation_normalized_percentile': {'value': 0.969927, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '27', 'issue': '3', 'first_page': '243', 'last_page': '248'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10869', 'display_name': 'Polysaccharides and Plant Cell Walls', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10869', 'display_name': 'Polysaccharides and Plant Cell Walls', 'score': 0.9991, 'subfield': {'id': 'https://openalex.org/subfields/1110', 'display_name': 'Plant Science'}, 'field': {'id': 'https://openalex.org/fields/11', 'display_name': 'Agricultural and Biological Sciences'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10602', 'display_name': 'Glycosylation and Glycoproteins Research', 'score': 0.9982, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10276', 'display_name': 'Helicobacter pylori-related gastroenterology studies', 'score': 0.9977, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/pepsin', 'display_name': 'Pepsin', 'score': 0.9858953}, {'id': 'https://openalex.org/keywords/peptic', 'display_name': 'Peptic', 'score': 0.45180973}], 'concepts': [{'id': 'https://openalex.org/C16311235', 'wikidata': 'https://www.wikidata.org/wiki/Q190265', 'display_name': 'Pepsin', 'level': 3, 'score': 0.9858953}, {'id': 'https://openalex.org/C2777312293', 'wikidata': 'https://www.wikidata.org/wiki/Q3649349', 'display_name': 'Mucus', 'level': 2, 'score': 0.80078846}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.5268104}, {'id': 'https://openalex.org/C2779422922', 'wikidata': 'https://www.wikidata.org/wiki/Q1029907', 'display_name': 'Stomach', 'level': 2, 'score': 0.4896143}, {'id': 'https://openalex.org/C2779390736', 'wikidata': 'https://www.wikidata.org/wiki/Q17095243', 'display_name': 'Peptic', 'level': 3, 'score': 0.45180973}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.4505001}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.40683207}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.35515153}, {'id': 'https://openalex.org/C43617362', 'wikidata': 'https://www.wikidata.org/wiki/Q170050', 'display_name': 'Chromatography', 'level': 1, 'score': 0.33645454}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.27726024}, {'id': 'https://openalex.org/C2780656511', 'wikidata': 'https://www.wikidata.org/wiki/Q172941', 'display_name': 'Peptic ulcer', 'level': 2, 'score': 0.22949964}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.14246985}, {'id': 'https://openalex.org/C18903297', 'wikidata': 'https://www.wikidata.org/wiki/Q7150', 'display_name': 'Ecology', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009093', 'descriptor_name': 'Mucus', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010434', 'descriptor_name': 'Pepsin A', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D002850', 'descriptor_name': 'Chromatography, Gel', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004381', 'descriptor_name': 'Duodenal Ulcer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004381', 'descriptor_name': 'Duodenal Ulcer', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D005750', 'descriptor_name': 'Gastric Juice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005750', 'descriptor_name': 'Gastric Juice', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006023', 'descriptor_name': 'Glycoproteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006863', 'descriptor_name': 'Hydrogen-Ion Concentration', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007527', 'descriptor_name': 'Isoenzymes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009093', 'descriptor_name': 'Mucus', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010434', 'descriptor_name': 'Pepsin A', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010437', 'descriptor_name': 'Peptic Ulcer', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010437', 'descriptor_name': 'Peptic Ulcer', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010437', 'descriptor_name': 'Peptic Ulcer', 'qualifier_ui': 'Q000209', 'qualifier_name': 'etiology', 'is_major_topic': False}], 'locations_count': 4, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/gut.27.3.243', 'pdf_url': 'https://gut.bmj.com/content/27/3/243.full.pdf', 'source': {'id': 'https://openalex.org/S3251770', 'display_name': 'Gut', 'issn_l': '0017-5749', 'issn': ['0017-5749', '1468-3288'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc1433406', 'pdf_url': 'https://europepmc.org/articles/pmc1433406?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1433406', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/3084340', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1136/gut.27.3.243', 'pdf_url': 'https://gut.bmj.com/content/27/3/243.full.pdf', 'source': {'id': 'https://openalex.org/S3251770', 'display_name': 'Gut', 'issn_l': '0017-5749', 'issn': ['0017-5749', '1468-3288'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319945', 'host_organization_name': 'BMJ', 'host_organization_lineage': ['https://openalex.org/P4310319945'], 'host_organization_lineage_names': ['BMJ'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 29, 'referenced_works': ['https://openalex.org/W103220061', 'https://openalex.org/W145359749', 'https://openalex.org/W1519024628', 'https://openalex.org/W1613556434', 'https://openalex.org/W1810583075', 'https://openalex.org/W1970058812', 'https://openalex.org/W2005720945', 'https://openalex.org/W2050443004', 'https://openalex.org/W2056278250', 'https://openalex.org/W2072080924', 'https://openalex.org/W2076732912', 'https://openalex.org/W2087882552', 'https://openalex.org/W2105731494', 'https://openalex.org/W2122925130', 'https://openalex.org/W2132518346', 'https://openalex.org/W2157070863', 'https://openalex.org/W2161872080', 'https://openalex.org/W2188749728', 'https://openalex.org/W2197707281', 'https://openalex.org/W2292069179', 'https://openalex.org/W2311697164', 'https://openalex.org/W2312762335', 'https://openalex.org/W2335489334', 'https://openalex.org/W2397530056', 'https://openalex.org/W2413469445', 'https://openalex.org/W2739525788', 'https://openalex.org/W2922496551', 'https://openalex.org/W4214499909', 'https://openalex.org/W88725230'], 'related_works': ['https://openalex.org/W3143993013', 'https://openalex.org/W2918239156', 'https://openalex.org/W2765013527', 'https://openalex.org/W2417462133', 'https://openalex.org/W2075570949', 'https://openalex.org/W2071523097', 'https://openalex.org/W2065472464', 'https://openalex.org/W2056356317', 'https://openalex.org/W2038539304', 'https://openalex.org/W2005078896'], 'abstract_inverted_index': {'The': [0, 208], 'ability': [1], 'to': [2, 96, 135, 138, 237], 'digest': [3, 195], 'mucus,': [4], 'mucolytic': [5, 75, 115, 130, 152], 'activity': [6, 76, 116, 131, 153], 'of': [7, 12, 77, 117, 140, 158, 211, 217, 230], 'isolated': [8], 'pepsins': [9], 'and': [10, 88, 97, 203], 'samples': [11], 'human': [13, 34, 53, 58], 'gastric': [14, 30, 43, 145], 'juice': [15, 146, 216], 'has': [16], 'been': [17], 'assayed': [18], 'by': [19, 162, 227], 'measuring': [20], 'the': [21, 37, 61, 74, 114, 159, 179, 196, 215, 224, 231, 240, 246], 'fall': [22, 180], 'in': [23, 169, 181, 214, 239], 'viscosity': [24, 183], 'when': [25], 'incubated': [26], 'with': [27, 124, 178], 'purified': [28], 'pig': [29, 63], 'mucus': [31, 44, 160, 182, 197, 232], 'glycoprotein.': [32], 'Pure': [33], 'pepsin': [35, 54, 64, 70, 78, 90, 101, 109, 118, 141, 173, 192, 201, 212], '1,': [36], 'peptic': [38, 218], 'ulcer': [39, 126, 219], 'associated': [40, 177], 'pepsin,': [41], 'digested': [42], 'glycoprotein': [45, 161, 175], 'at': [46, 204], 'a': [47], 'faster': [48], 'rate': [49], 'than': [50, 200], 'did': [51], 'pure': [52], '3': [55, 102, 202], '(the': [56], 'principal': [57], 'pepsin),': [59], 'or': [60], 'equivalent': [62], '(pepsin': [65], 'A).': [66], 'At': [67, 106], 'pH': [68, 81, 99, 107, 133, 155, 206], '2.0': [69], '1': [71, 91, 110, 193, 213], 'had': [72, 103, 111], 'twice': [73], '3.': [79, 119], 'Above': [80], '3.8': [82], 'this': [83], 'difference': [84], 'became': [85], 'more': [86, 198], 'marked': [87], 'whereas': [89], 'caused': [92], 'substantial': [93, 129], 'mucolysis': [94], 'up': [95], 'including': [98], '5.1,': [100], 'minimal': [104], 'activity.': [105], '4.0': [108], 'six': [112], 'times': [113], 'Gastric': [120], 'juices': [121], 'from': [122, 147], 'patients': [123, 220], 'duodenal': [125, 241], 'each': [127], 'exhibited': [128, 150], 'between': [132], '2': [134], '5,': [136], 'similar': [137], 'that': [139, 166, 191], '1.': [142], 'In': [143], 'contrast,': [144], 'non-symptomatic': [148], 'volunteers': [149], 'little': [151], 'above': [154], '4.': [156], 'Analysis': [157], 'gel': [163], 'filtration': [164], 'showed': [165, 190], 'an': [167], 'increase': [168], 'lower': [170], 'molecular': [171], 'weight,': [172], 'degraded,': [174], 'was': [176], 'for': [184], 'all': [185], 'enzyme': [186], 'preparations.': [187], 'These': [188], 'results': [189], 'can': [194], 'effectively': [199], 'higher': [205], 'values.': [207], 'raised': [209], 'concentrations': [210], 'may': [221], 'thus': [222], 'promote': [223], 'ulcerative': [225], 'process': [226], 'increased': [228], 'erosion': [229], 'barrier': [233], 'under': [234], 'conditions': [235], 'likely': [236], 'pertain': [238], 'bulb': [242], 'as': [243, 245], 'well': [244], 'stomach.': [247]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2091182287', 'counts_by_year': [{'year': 2024, 'cited_by_count': 3}, {'year': 2021, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2024-12-11T03:31:57.760510', 'created_date': '2016-06-24'}