Publication Information

{'id': 'https://openalex.org/W2089477241', 'doi': 'https://doi.org/10.1016/s0378-1119(02)00410-9', 'title': 'Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes', 'display_name': 'Adenovirus vectors containing chimeric type 5 and type 35 fiber proteins exhibit altered and expanded tropism and increase the size limit of foreign genes', 'publication_year': 2002, 'publication_date': '2002-02-01', 'ids': {'openalex': 'https://openalex.org/W2089477241', 'doi': 'https://doi.org/10.1016/s0378-1119(02)00410-9', 'mag': '2089477241', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/12039033'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0378-1119(02)00410-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75702506', 'display_name': 'Gene', 'issn_l': '0378-1119', 'issn': ['0378-1119', '1879-0038'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5011409446', 'display_name': 'Hiroyuki Mizuguchi', 'orcid': 'https://orcid.org/0000-0003-0594-8178'}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Hiroyuki Mizuguchi', 'raw_affiliation_strings': ['Division of Biological Chemistry and Biologicals National Institute of Health Sciences 1‐18‐1 Kamiyoga, Setagaya‐ku Tokyo 158‐8501 Japan'], 'affiliations': [{'raw_affiliation_string': 'Division of Biological Chemistry and Biologicals National Institute of Health Sciences 1‐18‐1 Kamiyoga, Setagaya‐ku Tokyo 158‐8501 Japan', 'institution_ids': ['https://openalex.org/I1299303238']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100830454', 'display_name': 'Takao Hayakawa', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1299303238', 'display_name': 'National Institutes of Health', 'ror': 'https://ror.org/01cwqze88', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Takao Hayakawa', 'raw_affiliation_strings': ['Division of Biological Chemistry and Biologicals National Institute of Health Sciences 1‐18‐1 Kamiyoga, Setagaya‐ku Tokyo 158‐8501 Japan'], 'affiliations': [{'raw_affiliation_string': 'Division of Biological Chemistry and Biologicals National Institute of Health Sciences 1‐18‐1 Kamiyoga, Setagaya‐ku Tokyo 158‐8501 Japan', 'institution_ids': ['https://openalex.org/I1299303238']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2940, 'currency': 'USD', 'value_usd': 2940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 6.283, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 117, 'citation_normalized_percentile': {'value': 0.931343, 'is_in_top_1_percent': False, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '285', 'issue': '1-2', 'first_page': '69', 'last_page': '77'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10613', 'display_name': 'Virus-based gene therapy research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10613', 'display_name': 'Virus-based gene therapy research', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11663', 'display_name': 'Viral Infectious Diseases and Gene Expression in Insects', 'score': 0.9986, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11491', 'display_name': 'CAR-T cell therapy research', 'score': 0.9974, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/transduction', 'display_name': 'Transduction (biophysics)', 'score': 0.8198032}, {'id': 'https://openalex.org/keywords/tissue-tropism', 'display_name': 'Tissue tropism', 'score': 0.51907593}], 'concepts': [{'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.87074965}, {'id': 'https://openalex.org/C15152581', 'wikidata': 'https://www.wikidata.org/wiki/Q7833966', 'display_name': 'Transduction (biophysics)', 'level': 2, 'score': 0.8198032}, {'id': 'https://openalex.org/C35693153', 'wikidata': 'https://www.wikidata.org/wiki/Q239762', 'display_name': 'Tropism', 'level': 3, 'score': 0.7902154}, {'id': 'https://openalex.org/C32470452', 'wikidata': 'https://www.wikidata.org/wiki/Q2298489', 'display_name': 'Viral vector', 'level': 4, 'score': 0.6278075}, {'id': 'https://openalex.org/C153911025', 'wikidata': 'https://www.wikidata.org/wiki/Q7202', 'display_name': 'Molecular biology', 'level': 1, 'score': 0.5549814}, {'id': 'https://openalex.org/C2776954459', 'wikidata': 'https://www.wikidata.org/wiki/Q193447', 'display_name': 'Adenoviridae', 'level': 4, 'score': 0.52559114}, {'id': 'https://openalex.org/C92087593', 'wikidata': 'https://www.wikidata.org/wiki/Q427389', 'display_name': 'Vector (molecular biology)', 'level': 4, 'score': 0.5220073}, {'id': 'https://openalex.org/C159047783', 'wikidata': 'https://www.wikidata.org/wiki/Q7215', 'display_name': 'Virology', 'level': 1, 'score': 0.5196613}, {'id': 'https://openalex.org/C33602714', 'wikidata': 'https://www.wikidata.org/wiki/Q7809666', 'display_name': 'Tissue tropism', 'level': 4, 'score': 0.51907593}, {'id': 'https://openalex.org/C111599444', 'wikidata': 'https://www.wikidata.org/wiki/Q213901', 'display_name': 'Genetic enhancement', 'level': 3, 'score': 0.47892985}, {'id': 'https://openalex.org/C123894998', 'wikidata': 'https://www.wikidata.org/wiki/Q425158', 'display_name': 'Fusion protein', 'level': 4, 'score': 0.46664622}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.41661215}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.35770205}, {'id': 'https://openalex.org/C2522874641', 'wikidata': 'https://www.wikidata.org/wiki/Q808', 'display_name': 'Virus', 'level': 2, 'score': 0.20048675}, {'id': 'https://openalex.org/C40767141', 'wikidata': 'https://www.wikidata.org/wiki/Q285697', 'display_name': 'Recombinant DNA', 'level': 3, 'score': 0.19552687}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.1460205}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.06184894}], 'mesh': [{'descriptor_ui': 'D000256', 'descriptor_name': 'Adenoviridae', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D002213', 'descriptor_name': 'Capsid', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D005822', 'descriptor_name': 'Genetic Vectors', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': True}, {'descriptor_ui': 'D000256', 'descriptor_name': 'Adenoviridae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002213', 'descriptor_name': 'Capsid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002213', 'descriptor_name': 'Capsid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D002460', 'descriptor_name': 'Cell Line', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004274', 'descriptor_name': 'DNA, Recombinant', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004274', 'descriptor_name': 'DNA, Recombinant', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015870', 'descriptor_name': 'Gene Expression', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005822', 'descriptor_name': 'Genetic Vectors', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005822', 'descriptor_name': 'Genetic Vectors', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D006367', 'descriptor_name': 'HeLa Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007275', 'descriptor_name': 'Injections, Intravenous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007668', 'descriptor_name': 'Kidney', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008099', 'descriptor_name': 'Liver', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D008156', 'descriptor_name': 'Luciferases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008168', 'descriptor_name': 'Lung', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051379', 'descriptor_name': 'Mice', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008810', 'descriptor_name': 'Mice, Inbred C57BL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018613', 'descriptor_name': 'Microscopy, Confocal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008856', 'descriptor_name': 'Microscopy, Fluorescence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D010957', 'descriptor_name': 'Plasmids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}, {'descriptor_ui': 'D011993', 'descriptor_name': 'Recombinant Fusion Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013154', 'descriptor_name': 'Spleen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': False}, {'descriptor_ui': 'D014162', 'descriptor_name': 'Transfection', 'qualifier_ui': 'Q000592', 'qualifier_name': 'standards', 'is_major_topic': False}, {'descriptor_ui': 'D019076', 'descriptor_name': 'Transgenes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019076', 'descriptor_name': 'Transgenes', 'qualifier_ui': 'Q000235', 'qualifier_name': 'genetics', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0378-1119(02)00410-9', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S75702506', 'display_name': 'Gene', 'issn_l': '0378-1119', 'issn': ['0378-1119', '1879-0038'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/12039033', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 40, 'referenced_works': ['https://openalex.org/W120480743', 'https://openalex.org/W1489938529', 'https://openalex.org/W1516780335', 'https://openalex.org/W1919665734', 'https://openalex.org/W1981995096', 'https://openalex.org/W1983066201', 'https://openalex.org/W1986509391', 'https://openalex.org/W1995592807', 'https://openalex.org/W2000853857', 'https://openalex.org/W2015781495', 'https://openalex.org/W2019921823', 'https://openalex.org/W2021667186', 'https://openalex.org/W2022120278', 'https://openalex.org/W2026544727', 'https://openalex.org/W2029175314', 'https://openalex.org/W2032423151', 'https://openalex.org/W2041179764', 'https://openalex.org/W2051758487', 'https://openalex.org/W2055557234', 'https://openalex.org/W2057144899', 'https://openalex.org/W2065354528', 'https://openalex.org/W2065392104', 'https://openalex.org/W2093134342', 'https://openalex.org/W2098866087', 'https://openalex.org/W2111871633', 'https://openalex.org/W2116071714', 'https://openalex.org/W2116175479', 'https://openalex.org/W2119143622', 'https://openalex.org/W2133822846', 'https://openalex.org/W2134640243', 'https://openalex.org/W2147961945', 'https://openalex.org/W2153792353', 'https://openalex.org/W2158071204', 'https://openalex.org/W2158744232', 'https://openalex.org/W2162013743', 'https://openalex.org/W2162380590', 'https://openalex.org/W2175291125', 'https://openalex.org/W2322389503', 'https://openalex.org/W2497059924', 'https://openalex.org/W4236449906'], 'related_works': ['https://openalex.org/W4311955436', 'https://openalex.org/W2607411891', 'https://openalex.org/W2570345100', 'https://openalex.org/W2563823608', 'https://openalex.org/W2410005479', 'https://openalex.org/W2321298962', 'https://openalex.org/W2026008144', 'https://openalex.org/W2014983986', 'https://openalex.org/W2002382263', 'https://openalex.org/W1594053245'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2089477241', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 6}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 1}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-12-25T09:55:18.551273', 'created_date': '2016-06-24'}