Title: Habituation to intense acoustic stimulation during cortical spreading depression in rats☆
Abstract: Few investigations have focused on the effects of cortical spreading depression (CSD) on habituation. In the 2 experiments to be reported here long-term habituation to intense acoustic stimulation was investigated. Arrest of ongoing drinking behavior was used as an index of habituation. In the first experiment habituation training during bilateral CSD was compared to habituation training under nondepressed conditions; testing for long-term habituation took place under nondepressed conditions in both groups. In contrast to the control group the bilateral CSD group did not show long-term habituation. In the second experiment habituation training during CSD in one hemisphere did not result in long term habituation when testing took place during CSD in the contralateral hemisphere. Possible explanations of these results are discussed.
Publication Year: 1976
Publication Date: 1976-07-01
Language: en
Type: article
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 6
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