Title: Ultrasonography of MADSAM neuropathy: Focal nerve enlargements at sites of existing and resolved conduction blocks
Abstract: I read with great interest the article by Scheidl et al. [ [1] Scheidl E. Böhm J. Simó M. et al. Ultrasonography of MADSAM neuropathy: focal nerve enlargements at sites of existing and resolved conduction blocks. Neuromuscul Disord. 2012; 22: 627-631 Abstract Full Text Full Text PDF PubMed Scopus (71) Google Scholar ] focused on the ultrasonography findings of the acquired demyelinating sensory and motor neuropathy (MADSAM). The authors depicted for the first time in the literature, that focal nerve enlargements can be detected by ultrasound in MADSAM, at sites of previous conduction blocks, well after complete clinical and electrophysiological resolution. This observation highlights in my opinion two important aspects in the clinical course of the disease. On one side, it shows that ultrasonographic morphological changes may outlast functional recovery in such demyelinating neuropathies. On the other side, this study highlights the fact that although the clinical course of the disease is expected to be predominantly in the upper extremities, morphological changes to the nerves of the lower extremities can be detected by ultrasound prior to clinical and electrophysiological affection. Ultrasonography of MADSAM neuropathy: Focal nerve enlargements at sites of existing and resolved conduction blocksNeuromuscular DisordersVol. 22Issue 7PreviewUsing the emerging technique of peripheral nerve ultrasonography, multiple focal nerve swellings corresponding to sites of existing conduction blocks have been described in demyelinating polyneuropathies. We report two cases of multifocal acquired demyelinating sensory and motor neuropathy (MADSAM). In the first, multiple focal nerve enlargements were detected by ultrasound at sites of previous conduction blocks, well after complete clinical and electrophysiological resolution. In the second case, existing proximal conduction blocks could be localized by ultrasound. Full-Text PDF
Publication Year: 2012
Publication Date: 2012-07-09
Language: en
Type: letter
Indexed In: ['crossref', 'pubmed']
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Cited By Count: 13
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