Publication Information

{'id': 'https://openalex.org/W2088730182', 'doi': 'https://doi.org/10.1111/j.1365-2567.2005.02144.x', 'title': 'Activated CD4<sup>+</sup> CD25<sup>+</sup> T cells suppress antigen‐specific CD4<sup>+</sup> and CD8<sup>+</sup> T cells but induce a suppressive phenotype only in CD4<sup>+</sup> T cells', 'display_name': 'Activated CD4<sup>+</sup> CD25<sup>+</sup> T cells suppress antigen‐specific CD4<sup>+</sup> and CD8<sup>+</sup> T cells but induce a suppressive phenotype only in CD4<sup>+</sup> T cells', 'publication_year': 2005, 'publication_date': '2005-06-09', 'ids': {'openalex': 'https://openalex.org/W2088730182', 'doi': 'https://doi.org/10.1111/j.1365-2567.2005.02144.x', 'mag': '2088730182', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/15946248', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/1782171'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2567.2005.02144.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89865888', 'display_name': 'Immunology', 'issn_l': '0019-2805', 'issn': ['0019-2805', '1365-2567'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'green', 'oa_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782171', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5064354433', 'display_name': 'Detlef Dieckmann', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Detlef Dieckmann', 'raw_affiliation_strings': ['Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,', 'institution_ids': ['https://openalex.org/I4210088053']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5024850820', 'display_name': 'Heidi Plöttner', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Heidi Plöttner', 'raw_affiliation_strings': ['Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,', 'institution_ids': ['https://openalex.org/I4210088053']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088475643', 'display_name': 'Stefanie Dotterweich', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Stefanie Dotterweich', 'raw_affiliation_strings': ['Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,', 'institution_ids': ['https://openalex.org/I4210088053']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5064778812', 'display_name': 'Gerold Schuler', 'orcid': 'https://orcid.org/0000-0002-5031-7562'}, 'institutions': [{'id': 'https://openalex.org/I4210088053', 'display_name': 'Universitätsklinikum Erlangen', 'ror': 'https://ror.org/0030f2a11', 'country_code': 'DE', 'type': 'healthcare', 'lineage': ['https://openalex.org/I4210088053']}], 'countries': ['DE'], 'is_corresponding': False, 'raw_author_name': 'Gerold Schuler', 'raw_affiliation_strings': ['Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,'], 'affiliations': [{'raw_affiliation_string': 'Department of Dermatology, University Hospital of Erlangen, Erlangen, Germany,', 'institution_ids': ['https://openalex.org/I4210088053']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.789, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 34, 'citation_normalized_percentile': {'value': 0.75068, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '115', 'issue': '3', 'first_page': '305', 'last_page': '314'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11020', 'display_name': 'Immune Cell Function and Interaction', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10031', 'display_name': 'T-cell and B-cell Immunology', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2403', 'display_name': 'Immunology'}, 'field': {'id': 'https://openalex.org/fields/24', 'display_name': 'Immunology and Microbiology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11491', 'display_name': 'CAR-T cell therapy research', 'score': 0.9994, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/interleukin-3', 'display_name': 'Interleukin 3', 'score': 0.46646655}], 'concepts': [{'id': 'https://openalex.org/C79484868', 'wikidata': 'https://www.wikidata.org/wiki/Q5971673', 'display_name': 'IL-2 receptor', 'level': 4, 'score': 0.8740428}, {'id': 'https://openalex.org/C129374314', 'wikidata': 'https://www.wikidata.org/wiki/Q909381', 'display_name': 'Interleukin 21', 'level': 4, 'score': 0.68424755}, {'id': 'https://openalex.org/C154317977', 'wikidata': 'https://www.wikidata.org/wiki/Q376266', 'display_name': 'Cytotoxic T cell', 'level': 3, 'score': 0.6152942}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.57942945}, {'id': 'https://openalex.org/C167672396', 'wikidata': 'https://www.wikidata.org/wiki/Q417800', 'display_name': 'CD8', 'level': 3, 'score': 0.52952975}, {'id': 'https://openalex.org/C67662055', 'wikidata': 'https://www.wikidata.org/wiki/Q1047791', 'display_name': 'Antigen-presenting cell', 'level': 4, 'score': 0.46745047}, {'id': 'https://openalex.org/C131665280', 'wikidata': 'https://www.wikidata.org/wiki/Q14866169', 'display_name': 'Interleukin 3', 'level': 5, 'score': 0.46646655}, {'id': 'https://openalex.org/C2778690821', 'wikidata': 'https://www.wikidata.org/wiki/Q212354', 'display_name': 'Cytokine', 'level': 2, 'score': 0.45760655}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.4384811}, {'id': 'https://openalex.org/C147483822', 'wikidata': 'https://www.wikidata.org/wiki/Q103537', 'display_name': 'Antigen', 'level': 2, 'score': 0.43269488}, {'id': 'https://openalex.org/C8891405', 'wikidata': 'https://www.wikidata.org/wiki/Q1059', 'display_name': 'Immune system', 'level': 2, 'score': 0.42958453}, {'id': 'https://openalex.org/C2776090121', 'wikidata': 'https://www.wikidata.org/wiki/Q193529', 'display_name': 'T cell', 'level': 3, 'score': 0.41790423}, {'id': 'https://openalex.org/C149532602', 'wikidata': 'https://www.wikidata.org/wiki/Q2409681', 'display_name': 'Interleukin 12', 'level': 4, 'score': 0.4109165}, {'id': 'https://openalex.org/C139563560', 'wikidata': 'https://www.wikidata.org/wiki/Q224930', 'display_name': 'Natural killer T cell', 'level': 4, 'score': 0.41013482}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.31764513}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.2353436}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.053700298}], 'mesh': [{'descriptor_ui': 'D007108', 'descriptor_name': 'Immune Tolerance', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015375', 'descriptor_name': 'Receptors, Interleukin-2', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': True}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015496', 'descriptor_name': 'CD4-Positive T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018414', 'descriptor_name': 'CD8-Positive T-Lymphocytes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D002455', 'descriptor_name': 'Cell Division', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002455', 'descriptor_name': 'Cell Division', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002999', 'descriptor_name': 'Clone Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002999', 'descriptor_name': 'Clone Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D018920', 'descriptor_name': 'Coculture Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D003713', 'descriptor_name': 'Dendritic Cells', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D004306', 'descriptor_name': 'Dose-Response Relationship, Immunologic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000939', 'descriptor_name': 'Epitopes', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007108', 'descriptor_name': 'Immune Tolerance', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007371', 'descriptor_name': 'Interferon-gamma', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016753', 'descriptor_name': 'Interleukin-10', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D015375', 'descriptor_name': 'Receptors, Interleukin-2', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016176', 'descriptor_name': 'T-Lymphocyte Subsets', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013601', 'descriptor_name': 'T-Lymphocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016212', 'descriptor_name': 'Transforming Growth Factor beta', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016212', 'descriptor_name': 'Transforming Growth Factor beta', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}], 'locations_count': 3, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1365-2567.2005.02144.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S89865888', 'display_name': 'Immunology', 'issn_l': '0019-2805', 'issn': ['0019-2805', '1365-2567'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782171', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/15946248', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1782171', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 36, 'referenced_works': ['https://openalex.org/W1509909867', 'https://openalex.org/W1575585006', 'https://openalex.org/W1599999513', 'https://openalex.org/W1976999017', 'https://openalex.org/W1979565071', 'https://openalex.org/W1985482500', 'https://openalex.org/W1999227421', 'https://openalex.org/W2002726823', 'https://openalex.org/W2010565041', 'https://openalex.org/W2019152707', 'https://openalex.org/W2021603971', 'https://openalex.org/W2026426963', 'https://openalex.org/W2045932062', 'https://openalex.org/W2046813754', 'https://openalex.org/W2062862675', 'https://openalex.org/W2076819781', 'https://openalex.org/W2087239120', 'https://openalex.org/W2097811455', 'https://openalex.org/W2101230909', 'https://openalex.org/W2108690268', 'https://openalex.org/W2122445377', 'https://openalex.org/W2123987776', 'https://openalex.org/W2130822830', 'https://openalex.org/W2133972276', 'https://openalex.org/W2137473611', 'https://openalex.org/W2139191751', 'https://openalex.org/W2144320908', 'https://openalex.org/W2146934919', 'https://openalex.org/W2148245227', 'https://openalex.org/W2157907412', 'https://openalex.org/W2159987448', 'https://openalex.org/W2161239722', 'https://openalex.org/W2161545566', 'https://openalex.org/W2169887956', 'https://openalex.org/W2564152524', 'https://openalex.org/W2737785069'], 'related_works': ['https://openalex.org/W2803531504', 'https://openalex.org/W2571232265', 'https://openalex.org/W2388776418', 'https://openalex.org/W2343712691', 'https://openalex.org/W2104899797', 'https://openalex.org/W2072502005', 'https://openalex.org/W2062567403', 'https://openalex.org/W2049687639', 'https://openalex.org/W2020960833', 'https://openalex.org/W2002809032'], 'abstract_inverted_index': {'CD4(+)': [0, 37, 55, 61, 84, 100, 110, 121, 140, 150, 184, 202], 'CD25(+)': [1, 38, 56, 85, 111, 141, 151, 203], 'regulatory': [2, 39, 57], 'T': [3, 40, 58, 62, 69, 86, 103, 112, 142, 152, 156, 181, 185, 204], 'cells': [4, 41, 59, 63, 87, 113, 143, 153, 157, 186], 'are': [5, 88, 114], 'increasingly': [6], 'recognized': [7], 'as': [8], 'central': [9], 'players': [10], 'in': [11, 47, 81], 'the': [12, 34, 72, 78, 92], 'regulation': [13], 'of': [14, 36, 97, 166], 'immune': [15, 45], 'responses.': [16], 'In': [17, 71], 'vitro': [18], 'studies': [19], 'have': [20], 'mostly': [21], 'employed': [22], 'allogeneic': [23], 'or': [24], 'polyclonal': [25], 'responses': [26, 46], 'to': [27, 42, 90, 129, 160, 190], 'monitor': [28], 'suppression.': [29], 'Little': [30], 'is': [31, 170], 'known': [32], 'about': [33], 'ability': [35], 'suppress': [43], 'antigen-specific': [44], 'humans.': [48], 'It': [49], 'has': [50], 'been': [51], 'previously': [52], 'shown': [53], 'that': [54, 83, 120], 'anergize': [60], 'and': [64, 94, 101, 132, 144, 163, 172, 194], 'turn': [65], 'them': [66], 'into': [67], 'suppressor': [68], 'cells.': [70, 104, 205], 'present': [73], 'study': [74], 'we': [75, 117], 'demonstrate': [76, 119], 'for': [77], 'first': [79], 'time': [80], 'humans': [82], 'able': [89], 'inhibit': [91], 'proliferation': [93, 162], 'cytokine': [95], 'production': [96, 165], 'antigen': [98], 'specific': [99], 'CD8(+)': [102, 155, 180], 'This': [105, 168], 'suppression': [106], 'only': [107], 'occurs': [108], 'when': [109], 'preactivated.': [115], 'Furthermore,': [116], 'could': [118], 'T-cell': [122], 'clones': [123], 'stop': [124], 'secreting': [125], 'interferon-gamma': [126], '(IFN-gamma),': [127], 'start': [128, 189], 'produce': [130, 191], 'interleukin-10': [131], 'transforming': [133], 'growth': [134], 'factor-beta': [135], 'after': [136, 199], 'coculture': [137, 200], 'with': [138, 201], 'preactivated': [139, 149], 'become': [145, 197], 'suppressive': [146, 198], 'themselves.': [147], 'Surprisingly': [148], 'affect': [154], 'differently,': [158], 'leading': [159], 'reduced': [161, 164], 'IFN-gamma.': [167], 'effect': [169], 'sustained': [171], 'cannot': [173], 'be': [174], 'reverted': [175], 'by': [176], 'exogenous': [177], 'interleukin-2.': [178], 'Yet': [179], 'cells,': [182], 'unlike': [183], 'do': [187, 195], 'not': [188, 196], 'immunoregulatory': [192], 'cytokines': [193]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2088730182', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 3}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-12-08T18:55:00.061724', 'created_date': '2016-06-24'}