Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2088525612', 'doi': 'https://doi.org/10.1016/j.juro.2010.02.654', 'title': '1155 EXPRESSION OF CYCLOOXYGENASE-2 IN SQUAMOUS CELL CARCINOMA OF THE URINARY BLADDER', 'display_name': '1155 EXPRESSION OF CYCLOOXYGENASE-2 IN SQUAMOUS CELL CARCINOMA OF THE URINARY BLADDER', 'publication_year': 2010, 'publication_date': '2010-03-23', 'ids': {'openalex': 'https://openalex.org/W2088525612', 'doi': 'https://doi.org/10.1016/j.juro.2010.02.654', 'mag': '2088525612'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2010.02.654', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5109137714', 'display_name': 'Ramy F. Youssef', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Ramy Youssef', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5079401169', 'display_name': 'Shahrokh F. Shariat', 'orcid': 'https://orcid.org/0000-0002-6627-6179'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Shahrokh Shariat', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069582117', 'display_name': 'Wareef Kabbani', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Wareef Kabbani', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069595062', 'display_name': 'Payal Kapur', 'orcid': None}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Payal Kapur', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5103390448', 'display_name': 'Ahmed Mosbah', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Ahmed Mosbah', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5070428699', 'display_name': 'Hassan Abol‐Enein', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Hassan Abol-Enein', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5113647698', 'display_name': 'Mohamed Ghoniem', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I159247623', 'display_name': 'Mansoura University', 'ror': 'https://ror.org/01k8vtd75', 'country_code': 'EG', 'type': 'education', 'lineage': ['https://openalex.org/I159247623']}], 'countries': ['EG'], 'is_corresponding': False, 'raw_author_name': 'Mohamed Ghoniem', 'raw_affiliation_strings': ['Mansoura, Egypt'], 'affiliations': [{'raw_affiliation_string': 'Mansoura, Egypt', 'institution_ids': ['https://openalex.org/I159247623']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5041923034', 'display_name': 'Yair Lotan', 'orcid': 'https://orcid.org/0000-0001-5692-2723'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'Yair Lotan', 'raw_affiliation_strings': ['Dallas, TX'], 'affiliations': [{'raw_affiliation_string': 'Dallas, TX', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 0.311, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 1, 'citation_normalized_percentile': {'value': 0.52305, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 64, 'max': 71}, 'biblio': {'volume': '183', 'issue': '4S', 'first_page': None, 'last_page': None}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10458', 'display_name': 'Bladder and Urothelial Cancer Treatments', 'score': 0.998, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10678', 'display_name': 'Inflammatory mediators and NSAID effects', 'score': 0.9894, 'subfield': {'id': 'https://openalex.org/subfields/2736', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T11332', 'display_name': 'Genomics, phytochemicals, and oxidative stress', 'score': 0.9685, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/urinary-diversion', 'display_name': 'Urinary diversion', 'score': 0.50496227}, {'id': 'https://openalex.org/keywords/interquartile-range', 'display_name': 'Interquartile range', 'score': 0.43544477}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8719907}, {'id': 'https://openalex.org/C2775910329', 'wikidata': 'https://www.wikidata.org/wiki/Q245995', 'display_name': 'Cystectomy', 'level': 4, 'score': 0.81515175}, {'id': 'https://openalex.org/C2780352672', 'wikidata': 'https://www.wikidata.org/wiki/Q504775', 'display_name': 'Bladder cancer', 'level': 3, 'score': 0.5203302}, {'id': 'https://openalex.org/C2777284795', 'wikidata': 'https://www.wikidata.org/wiki/Q7900621', 'display_name': 'Urinary diversion', 'level': 5, 'score': 0.50496227}, {'id': 'https://openalex.org/C2780849966', 'wikidata': 'https://www.wikidata.org/wiki/Q170758', 'display_name': 'Lymph node', 'level': 2, 'score': 0.45001405}, {'id': 'https://openalex.org/C126894567', 'wikidata': 'https://www.wikidata.org/wiki/Q105650', 'display_name': 'Urology', 'level': 1, 'score': 0.44532764}, {'id': 'https://openalex.org/C119060515', 'wikidata': 'https://www.wikidata.org/wiki/Q1916617', 'display_name': 'Interquartile range', 'level': 2, 'score': 0.43544477}, {'id': 'https://openalex.org/C2779762690', 'wikidata': 'https://www.wikidata.org/wiki/Q9382', 'display_name': 'Urinary bladder', 'level': 2, 'score': 0.4230036}, {'id': 'https://openalex.org/C2777546739', 'wikidata': 'https://www.wikidata.org/wiki/Q33525', 'display_name': 'Carcinoma', 'level': 2, 'score': 0.41480905}, {'id': 'https://openalex.org/C29456083', 'wikidata': 'https://www.wikidata.org/wiki/Q1221899', 'display_name': 'Gynecology', 'level': 1, 'score': 0.40928054}, {'id': 'https://openalex.org/C121608353', 'wikidata': 'https://www.wikidata.org/wiki/Q12078', 'display_name': 'Cancer', 'level': 2, 'score': 0.28853542}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.28786343}], 'mesh': [], 'locations_count': 1, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/j.juro.2010.02.654', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S30525748', 'display_name': 'The Journal of Urology', 'issn_l': '0022-5347', 'issn': ['0022-5347', '1527-3792'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315671', 'host_organization_name': 'Lippincott Williams & Wilkins', 'host_organization_lineage': ['https://openalex.org/P4310315671', 'https://openalex.org/P4310318547'], 'host_organization_lineage_names': ['Lippincott Williams & Wilkins', 'Wolters Kluwer'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Zero hunger', 'score': 0.51, 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W3128330365', 'https://openalex.org/W3127820018', 'https://openalex.org/W3116962311', 'https://openalex.org/W3031809519', 'https://openalex.org/W3021842629', 'https://openalex.org/W2904128870', 'https://openalex.org/W2405857368', 'https://openalex.org/W2383341741', 'https://openalex.org/W2081200281', 'https://openalex.org/W1966645625'], 'abstract_inverted_index': {'You': [0], 'have': [1], 'accessJournal': [2], 'of': [3, 106, 114, 222, 238, 255, 293], 'UrologyBladder': [4], 'Cancer:': [5], 'Basic': [6], 'Research': [7], 'III1': [8], 'Apr': [9], '20101155': [10], 'EXPRESSION': [11], 'OF': [12, 18], 'CYCLOOXYGENASE-2': [13], 'IN': [14], 'SQUAMOUS': [15], 'CELL': [16], 'CARCINOMA': [17], 'THE': [19], 'URINARY': [20], 'BLADDER': [21], 'Ramy': [22, 39, 338], 'Youssef,': [23], 'Shahrokh': [24, 45, 347], 'Shariat,': [25], 'Wareef': [26, 51, 356], 'Kabbani,': [27], 'Payal': [28, 57, 365], 'Kapur,': [29], 'Ahmed': [30, 63, 374], 'Mosbah,': [31], 'Hassan': [32, 69, 383], 'Abol-Enein,': [33], 'Mohamed': [34, 75, 392], 'Ghoniem,': [35], 'and': [36, 81, 117, 178, 203, 243, 271, 295, 316, 334], 'Yair': [37, 82, 401], 'Lotan': [38, 84, 402], 'YoussefRamy': [40], 'Youssef': [41, 339], 'Dallas,': [42, 48, 54, 60, 85, 340, 349, 358, 367, 403], 'TX': [43, 49, 55, 61, 86, 341, 350, 359, 368, 404], ',': [44, 50, 56, 62, 68, 74, 80], 'ShariatShahrokh': [46], 'Shariat': [47, 348], 'KabbaniWareef': [52], 'Kabbani': [53, 357], 'KapurPayal': [58], 'Kapur': [59, 366], 'MosbahAhmed': [64], 'Mosbah': [65, 375], 'Mansoura,': [66, 72, 78, 376, 385, 394], 'Egypt': [67, 73, 79, 377, 386, 395], 'Abol-EneinHassan': [70], 'Abol-Enein': [71, 384], 'GhoniemMohamed': [76], 'Ghoniem': [77, 393], 'LotanYair': [83], 'View': [87], 'All': [88, 411], 'Author': [89], 'Informationhttps://doi.org/10.1016/j.juro.2010.02.654AboutPDF': [90], 'ToolsAdd': [91], 'to': [92], 'favoritesDownload': [93], 'CitationsTrack': [94], 'CitationsPermissionsReprints': [95], 'ShareFacebookTwitterLinked': [96], 'InEmail': [97], 'INTRODUCTION': [98], 'AND': [99], 'OBJECTIVES': [100], 'We': [101], 'assessed': [102], 'the': [103, 115, 236, 288], 'expression': [104, 121, 215, 248], 'pattern': [105], 'cyclooxygenase-2': [107], '(cox-2)': [108], 'in': [109, 198, 281, 306], 'squamous': [110], 'cell': [111], 'carcinoma': [112], '(SCC)': [113], 'bladder': [116, 139, 282, 307], 'determined': [118], 'whether': [119], 'cox-2': [120, 134, 214, 247, 280, 294], 'is': [122, 266], 'associated': [123, 205, 217, 250, 267], 'with': [124, 146, 206, 218, 251, 268], 'clinical': [125], 'outcomes': [126, 272], 'after': [127, 273], 'radical': [128, 147, 274], 'cystectomy.': [129], 'METHODS': [130], 'Immunohistochemical': [131], 'staining': [132], 'for': [133, 149, 235, 279, 290], 'was': [135, 188, 196, 204, 216, 249], 'performed': [136], 'on': [137], 'archival': [138], 'specimens': [140, 201], 'from': [141], '152': [142], 'consecutive': [143], 'patients': [144, 152, 158, 180], 'treated': [145], 'cystectomy': [148, 200], 'SCC.': [150, 156, 308], '123': [151], '(81%)': [153], 'had': [154, 159, 164, 169, 174, 182], 'bilharzial-related': [155], 'Ten': [157], 'pT1': [160], 'SCC': [161, 166, 171, 176, 283], '(6.6%),': [162], '76': [163], 'pT2': [165], '(50%),': [167], '57': [168], 'pT3': [170], '(37.5%),': [172], '9': [173], 'pT4': [175], '(5.9%)': [177], '46': [179], '(30.3%)': [181], 'lymph': [183, 244], 'node': [184, 245], 'metastases.': [185], 'Median': [186], 'follow-up': [187], '63.2': [189], 'months': [190], '(interquartile': [191], 'range:': [192], '69.3).': [193], 'RESULTS': [194], 'Cox-2': [195], 'expressed': [197], '74': [199], '(48.7%)': [202], 'higher': [207], 'pathological': [208], 'stage': [209, 270], '(p=0.003).': [210], 'In': [211, 230], 'univariable': [212], 'analysis,': [213], 'an': [219, 252], 'increased': [220, 253], 'risk': [221, 254], 'disease': [223, 256], 'recurrence': [224, 257], '(HR': [225, 258], '2.06,': [226], '95%CI': [227, 260], '1.09-3.92,': [228], 'p=0.027).': [229], 'multivariable': [231], 'analysis': [232], 'that': [233], 'adjusted': [234], 'effects': [237], 'grade,': [239], 'stage,': [240], 'lymphovascular': [241], 'invasion,': [242], 'metastasis,': [246], '2.11,': [259], '1.10-4.06,': [261], 'p=0.024).': [262], 'CONCLUSIONS': [263], 'Cyclooxygenase-2': [264], 'overexpression': [265], 'pathologic': [269], 'cystectomy,': [275], 'suggesting': [276], 'a': [277], 'role': [278], 'progression.': [284], 'Our': [285], 'findings': [286], 'support': [287], 'need': [289], 'further': [291], 'evaluation': [292], 'inflammatory': [296], 'signaling': [297], 'pathways': [298], 'as': [299, 301], 'well': [300], 'cox-2-targeted': [302], 'prevention': [303], 'or': [304], 'therapies': [305], '©': [309], '2010': [310, 328], 'by': [311, 329, 344, 353, 362, 371, 380, 389, 398, 407], 'American': [312, 330], 'Urological': [313, 331], 'Association': [314, 332], 'Education': [315, 333], 'Research,': [317, 335], 'Inc.FiguresReferencesRelatedDetails': [318], 'Volume': [319], '183Issue': [320], '4SApril': [321], '2010Page:': [322], 'e447': [323], 'Advertisement': [324, 412, 413], 'Copyright': [325], '&': [326], 'Permissions©': [327], 'Inc.MetricsAuthor': [336], 'Information': [337], 'More': [342, 351, 360, 369, 378, 387, 396, 405], 'articles': [343, 352, 361, 370, 379, 388, 397, 406], 'this': [345, 354, 363, 372, 381, 390, 399, 408], 'author': [346, 355, 364, 373, 382, 391, 400, 409], 'Expand': [410], 'PDF': [414], 'downloadLoading': [415], '...': [416]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2088525612', 'counts_by_year': [], 'updated_date': '2024-12-24T14:32:44.174616', 'created_date': '2016-06-24'}