Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2088196123', 'doi': 'https://doi.org/10.3109/17435390.2010.502979', 'title': 'Titanium dioxide nanoparticles induced intracellular calcium homeostasis modification in primary human keratinocytes. Towards an<i>in vitro</i>explanation of titanium dioxide nanoparticles toxicity', 'display_name': 'Titanium dioxide nanoparticles induced intracellular calcium homeostasis modification in primary human keratinocytes. Towards an<i>in vitro</i>explanation of titanium dioxide nanoparticles toxicity', 'publication_year': 2010, 'publication_date': '2010-07-15', 'ids': {'openalex': 'https://openalex.org/W2088196123', 'doi': 'https://doi.org/10.3109/17435390.2010.502979', 'mag': '2088196123', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/21425910'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/17435390.2010.502979', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S193535841', 'display_name': 'Nanotoxicology', 'issn_l': '1743-5390', 'issn': ['1743-5390', '1743-5404'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5091281745', 'display_name': 'Marina Simón', 'orcid': 'https://orcid.org/0000-0002-6996-5105'}, 'institutions': [{'id': 'https://openalex.org/I4210125595', 'display_name': 'Laboratoire de Physique des deux infinis Bordeaux', 'ror': 'https://ror.org/034a4bk84', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I15057530', 'https://openalex.org/I4210125595', 'https://openalex.org/I4210133362']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marina Simon', 'raw_affiliation_strings': ["Centre d'Etudes Nucléaires de Bordeaux Gradignan"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes Nucléaires de Bordeaux Gradignan", 'institution_ids': ['https://openalex.org/I4210125595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5069553677', 'display_name': 'Philippe Barberet', 'orcid': 'https://orcid.org/0000-0002-1565-3296'}, 'institutions': [{'id': 'https://openalex.org/I4210125595', 'display_name': 'Laboratoire de Physique des deux infinis Bordeaux', 'ror': 'https://ror.org/034a4bk84', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I15057530', 'https://openalex.org/I4210125595', 'https://openalex.org/I4210133362']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Philippe Barberet', 'raw_affiliation_strings': ["Centre d'Etudes Nucléaires de Bordeaux Gradignan"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes Nucléaires de Bordeaux Gradignan", 'institution_ids': ['https://openalex.org/I4210125595']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5088155284', 'display_name': 'Marie‐Hélène Delville', 'orcid': 'https://orcid.org/0000-0001-8863-8225'}, 'institutions': [{'id': 'https://openalex.org/I4210110196', 'display_name': 'Institut de Chimie de la Matière Condensée de Bordeaux', 'ror': 'https://ror.org/01nw6qk38', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I15057530', 'https://openalex.org/I4210110196', 'https://openalex.org/I4210128300', 'https://openalex.org/I4210160189']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Marie-Hélène Delville', 'raw_affiliation_strings': ['Institut de Chimie de la Matière Condensée de Bordeaux'], 'affiliations': [{'raw_affiliation_string': 'Institut de Chimie de la Matière Condensée de Bordeaux', 'institution_ids': ['https://openalex.org/I4210110196']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5022587017', 'display_name': 'Philippe Moretto', 'orcid': 'https://orcid.org/0000-0001-9989-2958'}, 'institutions': [{'id': 'https://openalex.org/I4210125595', 'display_name': 'Laboratoire de Physique des deux infinis Bordeaux', 'ror': 'https://ror.org/034a4bk84', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I15057530', 'https://openalex.org/I4210125595', 'https://openalex.org/I4210133362']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Philippe Moretto', 'raw_affiliation_strings': ["Centre d'Etudes Nucléaires de Bordeaux Gradignan"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes Nucléaires de Bordeaux Gradignan", 'institution_ids': ['https://openalex.org/I4210125595']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5061945276', 'display_name': 'Hervé Seznec', 'orcid': 'https://orcid.org/0000-0001-6180-8925'}, 'institutions': [{'id': 'https://openalex.org/I4210125595', 'display_name': 'Laboratoire de Physique des deux infinis Bordeaux', 'ror': 'https://ror.org/034a4bk84', 'country_code': 'FR', 'type': 'facility', 'lineage': ['https://openalex.org/I1294671590', 'https://openalex.org/I15057530', 'https://openalex.org/I4210125595', 'https://openalex.org/I4210133362']}], 'countries': ['FR'], 'is_corresponding': False, 'raw_author_name': 'Hervé Seznec', 'raw_affiliation_strings': ["Centre d'Etudes Nucléaires de Bordeaux Gradignan"], 'affiliations': [{'raw_affiliation_string': "Centre d'Etudes Nucléaires de Bordeaux Gradignan", 'institution_ids': ['https://openalex.org/I4210125595']}]}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': 1.339, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 51, 'citation_normalized_percentile': {'value': 0.819789, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '5', 'issue': '2', 'first_page': '125', 'last_page': '139'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10079', 'display_name': 'Nanotoxicology and Antimicrobial Nanoparticles', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10079', 'display_name': 'Nanotoxicology and Antimicrobial Nanoparticles', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2505', 'display_name': 'Materials Chemistry'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T12627', 'display_name': 'Biomedical Applications of Graphene Nanomaterials', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2204', 'display_name': 'Biomedical Engineering'}, 'field': {'id': 'https://openalex.org/fields/22', 'display_name': 'Engineering'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10063', 'display_name': 'Nanoparticle-Based Drug Delivery Systems', 'score': 0.9897, 'subfield': {'id': 'https://openalex.org/subfields/2502', 'display_name': 'Biomaterials'}, 'field': {'id': 'https://openalex.org/fields/25', 'display_name': 'Materials Science'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/titanium-dioxide', 'display_name': 'Titanium dioxide', 'score': 0.7746241}, {'id': 'https://openalex.org/keywords/nanotoxicology', 'display_name': 'Nanotoxicology', 'score': 0.54615575}, {'id': 'https://openalex.org/keywords/nanoparticles', 'display_name': 'Nanoparticles', 'score': 0.480322}, {'id': 'https://openalex.org/keywords/surface-modification', 'display_name': 'Surface modification', 'score': 0.4150241}], 'concepts': [{'id': 'https://openalex.org/C2777593239', 'wikidata': 'https://www.wikidata.org/wiki/Q193521', 'display_name': 'Titanium dioxide', 'level': 2, 'score': 0.7746241}, {'id': 'https://openalex.org/C155672457', 'wikidata': 'https://www.wikidata.org/wiki/Q61231', 'display_name': 'Nanoparticle', 'level': 2, 'score': 0.6446525}, {'id': 'https://openalex.org/C192562407', 'wikidata': 'https://www.wikidata.org/wiki/Q228736', 'display_name': 'Materials science', 'level': 0, 'score': 0.5905793}, {'id': 'https://openalex.org/C202751555', 'wikidata': 'https://www.wikidata.org/wiki/Q221681', 'display_name': 'In vitro', 'level': 2, 'score': 0.59042734}, {'id': 'https://openalex.org/C519063684', 'wikidata': 'https://www.wikidata.org/wiki/Q706', 'display_name': 'Calcium', 'level': 2, 'score': 0.5869183}, {'id': 'https://openalex.org/C127445965', 'wikidata': 'https://www.wikidata.org/wiki/Q2518429', 'display_name': 'Nanotoxicology', 'level': 3, 'score': 0.54615575}, {'id': 'https://openalex.org/C29730261', 'wikidata': 'https://www.wikidata.org/wiki/Q274160', 'display_name': 'Toxicity', 'level': 2, 'score': 0.50946885}, {'id': 'https://openalex.org/C79879829', 'wikidata': 'https://www.wikidata.org/wiki/Q5571762', 'display_name': 'Intracellular', 'level': 2, 'score': 0.41908064}, {'id': 'https://openalex.org/C115537861', 'wikidata': 'https://www.wikidata.org/wiki/Q7645993', 'display_name': 'Surface modification', 'level': 2, 'score': 0.4150241}, {'id': 'https://openalex.org/C171250308', 'wikidata': 'https://www.wikidata.org/wiki/Q11468', 'display_name': 'Nanotechnology', 'level': 1, 'score': 0.34036848}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.3331402}, {'id': 'https://openalex.org/C42360764', 'wikidata': 'https://www.wikidata.org/wiki/Q83588', 'display_name': 'Chemical engineering', 'level': 1, 'score': 0.28655708}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.2788331}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.15641132}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.11572471}, {'id': 'https://openalex.org/C191897082', 'wikidata': 'https://www.wikidata.org/wiki/Q11467', 'display_name': 'Metallurgy', 'level': 1, 'score': 0.108906776}, {'id': 'https://openalex.org/C178790620', 'wikidata': 'https://www.wikidata.org/wiki/Q11351', 'display_name': 'Organic chemistry', 'level': 1, 'score': 0.06452647}, {'id': 'https://openalex.org/C127413603', 'wikidata': 'https://www.wikidata.org/wiki/Q11023', 'display_name': 'Engineering', 'level': 0, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D006706', 'descriptor_name': 'Homeostasis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': True}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D053758', 'descriptor_name': 'Nanoparticles', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D014025', 'descriptor_name': 'Titanium', 'qualifier_ui': 'Q000633', 'qualifier_name': 'toxicity', 'is_major_topic': True}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000199', 'descriptor_name': 'Actins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002118', 'descriptor_name': 'Calcium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002478', 'descriptor_name': 'Cells, Cultured', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D019544', 'descriptor_name': 'Equipment Failure Analysis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005456', 'descriptor_name': 'Fluorescent Dyes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005456', 'descriptor_name': 'Fluorescent Dyes', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015603', 'descriptor_name': 'Keratinocytes', 'qualifier_ui': 'Q000648', 'qualifier_name': 'ultrastructure', 'is_major_topic': False}, {'descriptor_ui': 'D018613', 'descriptor_name': 'Microscopy, Confocal', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D046529', 'descriptor_name': 'Microscopy, Electron, Transmission', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053758', 'descriptor_name': 'Nanoparticles', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D053758', 'descriptor_name': 'Nanoparticles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D014025', 'descriptor_name': 'Titanium', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D014025', 'descriptor_name': 'Titanium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.3109/17435390.2010.502979', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S193535841', 'display_name': 'Nanotoxicology', 'issn_l': '1743-5390', 'issn': ['1743-5390', '1743-5404'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320547', 'host_organization_name': 'Taylor & Francis', 'host_organization_lineage': ['https://openalex.org/P4310320547'], 'host_organization_lineage_names': ['Taylor & Francis'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.science/hal-00598703', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-03127151', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://hal.archives-ouvertes.fr/hal-00598703', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306402512', 'display_name': 'HAL (Le Centre pour la Communication Scientifique Directe)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1294671590', 'host_organization_name': 'Centre National de la Recherche Scientifique', 'host_organization_lineage': ['https://openalex.org/I1294671590'], 'host_organization_lineage_names': ['Centre National de la Recherche Scientifique'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/21425910', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 59, 'referenced_works': ['https://openalex.org/W1136070835', 'https://openalex.org/W1485297825', 'https://openalex.org/W1564553363', 'https://openalex.org/W1964123007', 'https://openalex.org/W1965984529', 'https://openalex.org/W1966522769', 'https://openalex.org/W1968012736', 'https://openalex.org/W1969383560', 'https://openalex.org/W1970342030', 'https://openalex.org/W1975151811', 'https://openalex.org/W1977412307', 'https://openalex.org/W1982347298', 'https://openalex.org/W1982769493', 'https://openalex.org/W1987202454', 'https://openalex.org/W1990540805', 'https://openalex.org/W1994060267', 'https://openalex.org/W1995478063', 'https://openalex.org/W2009620021', 'https://openalex.org/W2011254969', 'https://openalex.org/W2013374807', 'https://openalex.org/W2022014262', 'https://openalex.org/W2026885641', 'https://openalex.org/W2029533392', 'https://openalex.org/W2038775838', 'https://openalex.org/W2041530239', 'https://openalex.org/W2044778337', 'https://openalex.org/W2046000669', 'https://openalex.org/W2050563255', 'https://openalex.org/W2058416613', 'https://openalex.org/W2061073363', 'https://openalex.org/W2066490404', 'https://openalex.org/W2071396517', 'https://openalex.org/W2073541732', 'https://openalex.org/W2076759023', 'https://openalex.org/W2077537727', 'https://openalex.org/W2081572333', 'https://openalex.org/W2088583398', 'https://openalex.org/W2099191918', 'https://openalex.org/W2100750710', 'https://openalex.org/W2107198564', 'https://openalex.org/W2111836708', 'https://openalex.org/W2115910867', 'https://openalex.org/W2120910813', 'https://openalex.org/W2121710504', 'https://openalex.org/W2135980592', 'https://openalex.org/W2136194743', 'https://openalex.org/W2143222374', 'https://openalex.org/W2148801431', 'https://openalex.org/W2152752812', 'https://openalex.org/W2155118487', 'https://openalex.org/W2157489799', 'https://openalex.org/W2161988862', 'https://openalex.org/W2170472008', 'https://openalex.org/W2410959431', 'https://openalex.org/W2469365296', 'https://openalex.org/W2480766469', 'https://openalex.org/W4248285292', 'https://openalex.org/W4255760236', 'https://openalex.org/W4285719527'], 'related_works': ['https://openalex.org/W4324359039', 'https://openalex.org/W3106937478', 'https://openalex.org/W3092733610', 'https://openalex.org/W2918599941', 'https://openalex.org/W2893857', 'https://openalex.org/W2580284338', 'https://openalex.org/W2532540677', 'https://openalex.org/W2320083771', 'https://openalex.org/W2030012245', 'https://openalex.org/W1637325163'], 'abstract_inverted_index': {'Deciphering': [0], 'the': [1, 50, 58, 61, 92, 115, 118, 122, 134, 137, 144], 'molecular': [2], 'basis': [3], 'of': [4, 49, 60, 88, 111, 121, 136, 146], 'toxicology': [5], 'mechanism': [6], 'induced': [7, 96], 'by': [8], 'nanoparticles': [9], '(NPs)': [10], 'remains': [11], 'an': [12, 104], 'essential': [13], 'challenge.': [14], 'Ion': [15], 'Beam': [16], 'Analysis': [17], '(IBA)': [18], 'was': [19], 'applied': [20], 'in': [21, 84, 99, 126, 141], 'combination': [22], 'with': [23, 103], 'Transmission': [24], 'Electron': [25], 'Microscopy': [26, 29], 'and': [27, 56, 82, 95, 124, 132], 'Confocal': [28], 'to': [30, 35, 45, 57, 76, 143], 'analyze': [31], 'human': [32], 'keratinocytes': [33], 'exposed': [34], 'TiO(2)-NPs.': [36, 147], 'Investigating': [37], 'chemical': [38, 63], 'elemental': [39], 'distributions': [40], 'using': [41], 'IBA': [42], 'gives': [43], 'rise': [44], 'a': [46, 54, 97], 'fine': [47], 'quantification': [48, 81], 'TiO(2)-NPs': [51, 66, 72, 90, 123], 'uptake': [52], 'within': [53], 'cell': [55, 100, 112], 'determination': [59], 'intracellular': [62], 'modifications': [64], 'after': [65], 'internalization.': [67], 'In': [68], 'addition,': [69], 'fluorescent': [70], 'dye-modified': [71], 'have': [73], 'been': [74], 'synthesized': [75], 'allow': [77], 'their': [78, 125], 'detection,': [79], 'precise': [80], 'tracking': [83], 'vitro.': [85], 'The': [86], 'internalization': [87], 'these': [89], 'altered': [91], 'calcium': [93, 138], 'homeostasis': [94, 139], 'decrease': [98], 'proliferation': [101], 'associated': [102], 'early': [105], 'keratinocyte': [106], 'differentiation,': [107], 'without': [108], 'any': [109], 'indication': [110], 'death.': [113], 'Additionally,': [114], 'relation': [116], 'between': [117], 'surface': [119], 'chemistry': [120], 'vitro': [127], 'toxicity': [128], 'is': [129], 'clearly': [130], 'established': [131], 'emphasizes': [133], 'importance': [135], 'alteration': [140], 'response': [142], 'presence': [145]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2088196123', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 2}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 14}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 4}], 'updated_date': '2024-09-09T20:57:12.218765', 'created_date': '2016-06-24'}