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403, 717, 875, 1512], 'receptor-β': [15, 199, 374], '(TRβ)': [16, 200], 'in': [17, 32, 66, 78, 176, 201, 216, 250, 262, 360, 423, 528, 698, 871, 881, 903, 1011, 1044, 1048, 1116, 1181, 1241, 1261, 1282, 1302, 1333, 1368, 1406, 1477, 1516, 1570, 1597, 1610, 1638, 1664, 1742, 1782, 1790, 1796, 1802, 1810, 1851, 1877, 1880, 1925, 1990, 2079, 2108, 2209, 2250, 2299, 2316, 2407, 2421, 2457, 2507, 2560, 2581, 2593, 2603, 2622, 2651, 2661, 2681, 2710, 2740, 2824, 2861, 2890, 2924, 2948, 2984, 3038, 3050, 3059, 3068, 3145, 3148, 3514, 3646, 3766, 3856, 3896, 3958, 3976, 4131, 4205], 'living': [18, 202, 1262, 1369, 1598], 'cells,': [19, 203, 1370, 1860, 2439, 2632, 2683, 2712, 2742, 2966, 3480], 'utilizing': [20, 204], 'fusions': [21, 205, 1390], 'to': [22, 206, 401, 664, 707, 894, 1159, 1331, 1376, 1393, 1510, 1577, 1580, 1808, 2014, 2260, 2354, 2390, 2539, 2878, 2897, 3104, 3192, 3285, 3343, 3394, 3477, 3485, 3491, 3562, 3591, 3823, 3833, 3836, 3845, 4056, 4087, 4208], 'green': [24, 208, 380], 'fluorescent': [25, 209, 381], 'protein.': [26, 210], 'Wild-type': [27, 211, 2734], 'TRβ': [28, 75, 101, 114, 139, 149, 163, 212, 259, 285, 298, 323, 333, 347, 1023, 1173, 1231, 1291, 1314, 1327, 1367, 1382, 1397, 1605, 1741, 2283, 2387, 2614, 2727, 2735, 2837, 2910, 2927, 3200, 3306, 3782, 3874, 3960, 4136], 'was': [29, 213, 1568, 1575, 1645, 1659, 1682, 1708, 1856, 1867, 2077, 2155, 2245, 2338, 2368, 2435, 2449, 2503, 2537, 2628, 2640, 2690, 2719, 2749, 2846, 2869, 2906, 2976, 3056, 3066, 3097, 3124, 3141, 3325, 3456, 3463, 3483, 3654, 3783, 3800, 3814, 3865, 4069, 4094, 4194], 'mostly': [30, 214, 3057], 'nuclear': [31, 44, 58, 119, 126, 215, 228, 242, 303, 310, 378, 391, 674, 1155, 1252, 1285, 1300, 1319, 1355, 1420, 1693, 1900, 2003, 2410, 2478, 2596, 2758, 2871, 2937, 3013, 3040, 3070, 3084, 3235, 3390, 3504, 3549, 3715, 3762, 3774, 3863, 3871, 4162], 'both': [33, 57, 217, 241, 669, 1027, 1047, 1278, 1611, 1639, 1665, 2358, 2383, 3149, 3271, 3349, 3777, 3888, 3954, 4036, 4182], 'absence': [35, 219, 411, 700, 873, 1052, 1120, 1304, 1335, 1613, 1667, 1882, 1927, 2073, 2110, 2236, 2301, 2360, 2459, 2509, 2583, 2653, 2865, 2986, 2996, 3061, 3151, 4038, 4213], 'presence': [37, 221, 425, 702, 883, 1050, 1118, 1615, 1669, 1784, 1885, 1930, 2112, 2252, 2303, 2362, 2464, 2605, 2663, 2892, 2989, 3052, 3153, 3804, 3858, 4042, 4211], 'triiodothyronine;': [39, 223], 'however,': [40, 224], 'triiodothyronine': [41, 225, 371], 'induced': [42, 226], 'a': [43, 83, 227, 267, 481, 666, 898, 1169, 1175, 1233, 1322, 1373, 1394, 1454, 1735, 1923, 1991, 2080, 2094, 2151, 2184, 2194, 2202, 2220, 2267, 2293, 2343, 2404, 2550, 2825, 2921, 3036, 3301, 3381, 3405, 3767, 3808, 3837, 3977, 4101, 4129], 'reorganization': [45, 229], 'TRβ.': [47, 231, 1163, 1288, 2601, 3903, 4034], 'By': [48, 232, 1035], 'mutating': [49, 233], 'defined': [50, 234, 2185], 'regions': [51, 235], 'TRβ,': [53, 237, 1222, 3045], 'found': [55, 239, 1042, 1576, 1734, 2369, 3142, 3484, 3969, 4029], 'that': [56, 113, 148, 159, 240, 297, 332, 343, 688, 1006, 1149, 1270, 1293, 1340, 1414, 1461, 1545, 1581, 1601, 1655, 1717, 1746, 1817, 2398, 2530, 2879, 2905, 2917, 3077, 3095, 3270, 3298, 3404, 3449, 3454, 3497, 3773, 3870, 3970, 4066], 'corepressor': [59, 127, 243, 311, 379, 482, 1253, 1421], 'retinoid': [61, 129, 245, 313, 375, 2854], 'X': [62, 130, 246, 314, 376, 2855], 'receptor': [63, 70, 131, 247, 254, 315, 377, 1040, 1109, 1180, 1215, 1236, 1243, 1473, 1801, 2020, 2322, 2341, 2564, 2639, 2856, 3813, 3841, 3968, 3974, 3986, 4061, 4068, 4144], 'are': [64, 248, 390, 680, 866, 892, 1009, 1239, 1503, 1514, 1789, 2388, 2610, 3277, 4203], 'involved': [65, 249, 3067], 'maintaining': [67, 100, 137, 251, 284, 321, 1012, 2408, 2594, 2613, 2925, 3897, 3959], 'unliganded': [69, 138, 253, 322, 888, 1018, 1179, 1359, 1800, 2386, 2926, 3044, 3239, 3779, 3985, 4092, 4155], 'within': [71, 102, 140, 255, 286, 324, 1456, 1607, 1629, 1661, 1973, 1985, 2347, 2370, 2566, 2615, 2797, 2819, 2838, 2928, 3131, 3709, 3756, 3961, 4077], 'nucleus.': [73, 104, 142, 257, 288, 326, 1987, 2821, 4079], 'A': [74, 258, 1619, 1674, 1697, 2187, 2213, 2307, 2325, 2515, 2873, 3849], 'mutant': [76, 260, 2448, 2528, 3177], 'defective': [77, 261, 1240, 2860], 'DNA': [79, 94, 170, 263, 278, 354, 1113, 1160, 1248, 1332, 1476, 1714, 2400, 4215], 'binding': [80, 95, 264, 279, 400, 1161, 1475, 2401, 4125], 'had': [81, 265, 3168, 3201, 3431], 'only': [82, 266, 2403, 2920, 4127], 'slightly': [84, 268], 'altered': [85, 269], 'nuclear/cytoplasmic': [86, 270, 1706], 'compared': [88, 272], 'with': [89, 164, 273, 348, 473, 544, 897, 1153, 1168, 1272, 1276, 1346, 1418, 1508, 2313, 2393, 2501, 2599, 2852, 2881, 3109, 3166, 3194, 3216, 3220, 3293, 3329, 3384, 3420, 3521, 3564, 3570, 3584, 3601, 3632, 3641, 3816, 3912, 3922, 3965, 3980, 4033, 4072, 4109, 4145, 4159, 4169, 4189], 'wild-type': [90, 274, 1230, 1326, 1381, 1849, 2413, 2600, 2726, 2909], 'TRβ;': [91, 275], 'thus,': [92, 276, 659], 'site-specific': [93, 277, 2399], 'is': [96, 280, 662, 686, 1004, 1041, 1157, 1328, 1351, 1945, 2225, 2352, 2859, 2932, 3675, 3875, 3975], 'not': [97, 281, 1316, 1557, 1589, 1722, 1731, 2330, 2499, 2933, 4121, 4126, 4154], 'essential': [98, 282], 'for': [99, 283, 682, 1354, 1584, 1691, 2243, 2612, 2835, 2935, 3573, 3587, 3604, 3613], 'Both': [105, 289], 'ATP': [106, 290, 3337, 3530], 'depletion': [107, 291], 'studies': [108, 292, 1257, 1573, 1815, 1996, 3241, 3292], 'heterokaryon': [110, 294, 3466], 'analysis': [111, 295, 1543, 3467], 'demonstrated': [112, 296, 1600, 2529, 3949], 'rapidly': [115, 150, 299, 334, 3500], 'shuttles': [116, 151, 300, 335, 3409, 3455], 'between': [117, 152, 301, 336, 1813, 3310, 3410, 3502], 'cytoplasmic': [122, 306, 870, 1014, 1738, 2506, 3058, 3089, 3507, 3510], 'compartments.': [123, 307], 'Cotransfection': [124, 308], 'markedly': [132, 316, 1298], 'decreased': [133, 317, 1299], 'shuttling': [135, 319, 3511], 'by': [136, 320, 399, 673, 1028, 1162, 1748, 1869, 2164, 2201, 2227, 2451, 2642, 2978, 3187, 3242, 3288, 3458, 3465, 3531, 3656, 4196], 'summary,': [144, 328], 'our': [145, 329, 1787, 1814], 'findings': [146, 330, 1268, 3227, 3771], 'demonstrate': [147, 331, 2916], 'nucleus': [154, 338, 880, 1609, 1641, 1663, 2372, 2541, 2568, 2899, 2930, 3106, 3133, 3147, 3282, 3312, 3357, 3412, 3847, 3982, 4115], 'cytoplasm': [157, 341, 1183, 1644, 1804, 3287, 3396, 3825, 3844], 'protein-protein': [160, 344, 678], 'interactions': [161, 345, 679, 1008, 2587, 2609, 3892], 'various': [165, 349, 1214], 'cofactors,': [166, 350], 'rather': [167, 351], 'than': [168, 352, 1745, 2512, 2532, 3983], 'specific': [169, 353, 1112, 1242], 'interactions,': [171, 355], 'play': [172, 356, 1279, 2589], 'predominant': [174, 358], 'role': [175, 359, 2406, 2592, 2923, 3037, 3231], 'determining': [177, 361], 'receptor.': [183, 367], 'receptors': [370, 388, 842, 891, 1587, 1694, 3276, 3354], 'protein': [382, 1718, 1971, 1983, 2795, 2817, 3707, 3754], '4,6-diamidino-2-phenylindole': [383], 'phosphate-buffered': [384], 'saline': [385], 'Thyroid': [386], '(TRs)1': [389], 'receptors,': [393, 718, 2004], 'which': [394, 1238, 2288, 2497, 3055, 3332], 'can': [395, 530, 3499, 4157], 'directly': [396], 'regulate': [397], 'transcription': [398, 417, 430], 'response': [404], 'elements': [405], 'target': [407, 536], 'genes.': [408, 537], 'T3,': [413, 427, 2075, 2090, 2114, 2254, 2364, 2549, 2585, 2894, 3421], 'TRs': [414, 428, 471, 542, 697], 'repress': [415], 'basal': [416, 469], 'positively': [419], 'regulated': [420], 'genes,': [421], 'whereas': [422, 2249, 4100], 'activate': [429], '(1Koenig': [431], 'R.J.': [432, 630, 1126], 'Thyroid.': [433], '1998;': [434, 1195, 1763, 1833], '8:': [435], '703-713Crossref': [436], 'PubMed': [437, 498, 513, 583, 622, 654, 743, 764, 783, 808, 835, 861, 929, 953, 964, 986, 998, 1065, 1082, 1104, 1142, 1203, 1447, 1493, 1536, 1771, 1841, 2037, 2139, 3263, 3375, 4003], 'Scopus': [438, 499, 514, 584, 623, 655, 744, 765, 784, 809, 836, 862, 930, 965, 999, 1066, 1083, 1204, 1448, 1494, 1537, 1772, 1842, 2038, 2140, 3264, 3376, 4004], '(97)': [439], 'Google': [440, 466, 501, 516, 586, 625, 657, 746, 767, 786, 811, 838, 864, 932, 954, 967, 987, 1001, 1068, 1085, 1105, 1143, 1206, 1450, 1496, 1539, 1774, 1844, 2040, 2059, 2142, 3266, 3378, 4006, 4025], 'Scholar,': [441, 626, 747, 768, 812, 933, 955, 968, 988, 1069, 1086, 2041, 4007], '2Shibata': [442], 'H.': [443, 628, 724, 755, 794, 816, 2022, 2124, 3253, 3365, 3988], 'Spencer': [444], 'T.E.': [445, 597], 'Onate': [446, 610], 'S.A.': [447, 611], 'Jenster': [448, 598], 'G.': [449, 566, 599, 772], 'Tsai': [450, 452, 612, 614, 1057], 'S.Y.': [451, 613], 'M.J.': [453, 615, 974], "O'Malley": [454, 506, 616], 'B.W.': [455, 507, 617], 'Recent': [456], 'Prog.': [457], 'Horm.': [458], 'Res.': [459, 760, 779, 1077], '1997;': [460, 619, 646, 858], '52': [461], '(;': [462], 'Discussion': [463], '164–165):': [464], '141-164PubMed': [465], 'Scholar).': [467, 517, 587, 1002, 1106, 1207, 1451, 1497, 1540, 2060, 2143, 3379, 4026], 'repression,': [470], 'associate': [472, 543, 4158], 'corepressors': [474, 1350], 'such': [475, 523, 546, 555, 691, 719, 2005], 'as': [476, 524, 547, 556, 692, 720, 1687, 1905, 2006, 2207, 2297, 2483, 2692, 2721, 2751, 2765, 3018, 3101, 3113, 3183, 3535, 3554, 3576, 3644, 4177], 'N-CoR': [477, 1277, 1296, 1422, 2586, 2608, 2698, 2705, 3165, 3619, 3889, 3918, 3928, 3957], 'SMRT,': [479], 'forming': [480], 'complex': [483, 519, 899], '(3Xu': [484], 'L.': [485, 638], 'Glass': [486, 1441], 'C.K.': [487, 1442], 'Rosenfeld': [488], 'M.G.': [489], 'Curr.': [490], 'Opin.': [491], 'Genet.': [492], '&': [493], 'Dev.': [494], '1999;': [495, 510, 805, 2034, 2136, 4000], '9:': [496, 996], '140-147Crossref': [497], '(808)': [500], 'Scholar,4McKenna': [502], 'N.J.': [503, 609], 'Lanz': [504], 'R.B.': [505], 'Endocr.': [508, 1076], 'Rev.': [509], '20:': [511], '321-344Crossref': [512], '(1639)': [515], 'This': [518, 2340, 3461], 'includes': [520], 'other': [521, 689, 1692, 2002], 'components,': [522], 'histone': [525, 593], 'deacetylases,': [526], 'which,': [527], 'turn,': [529], 'alter': [531], 'chromatin': [533, 660], 'structure': [534], 'During': [538], 'transcriptional': [539, 683, 711, 1562], 'activation,': [540], 'liganded': [541, 2384, 2940, 3781, 4105], 'coactivators': [545], 'SRC-1': [548], 'form': [550], 'coactivator': [551], 'complexes,': [552], 'including': [553, 906, 1245], 'components': [554, 4147], 'CREB-binding': [558], 'protein,': [559], 'p300,': [560], 'P/CAF': [562], '(5Yao': [563], 'T.P.': [564], 'Ku': [565], 'Zhou': [567, 604], 'N.': [568, 774], 'Scully': [569], 'R.': [570, 1060, 1434], 'Livingston': [571], 'D.M.': [572], 'Proc.': [573, 733], 'Natl.': [574, 734], 'Acad.': [575, 735], 'Sci.': [576, 736], 'U.': [577, 737], 'S.': [578, 738, 753, 820, 1486, 1529, 3251, 3363], 'A.': [579, 636, 739, 814, 1436, 3247, 3359], '1996;': [580, 740], '93:': [581, 741], '10626-10631Crossref': [582], '(392)': [585], 'Several': [588], 'these': [590, 677, 890, 1007, 1037, 1651, 2395, 3226, 3906], 'factors': [591, 2832, 4076], 'acetyltransferase': [594], 'activity': [595, 1563], '(6Spencer': [596], 'Burcin': [600], 'M.M.': [601], 'Allis': [602], 'C.D.': [603], 'J.': [605, 726, 944, 977, 1092, 1095, 1133, 1192, 1430, 1760, 1830, 3259, 3371], 'Mizzen': [606], 'C.A.': [607], 'McKenna': [608], 'Nature.': [618, 1443], '389:': [620], '194-198Crossref': [621], '(1054)': [624], '7Chen': [627], 'Lin': [629], 'Schiltz': [631], 'R.L.': [632], 'Chakravarti': [633], 'D.': [634, 2026, 2043, 2128, 3992, 4009], 'Nash': [635], 'Nagy': [637], 'Privalsky': [639], 'M.L.': [640], 'Nakatani': [641], 'Y.': [642, 1438, 1484, 1527], 'Evans': [643], 'R.M.': [644], 'Cell.': [645, 828, 856, 959, 2033, 2135, 3999], '90:': [647], '569-580Abstract': [648], 'Full': [649, 651, 832, 950, 983, 1101, 1139, 1198, 1200, 1766, 1768, 1836, 1838], 'Text': [650, 652, 833, 951, 984, 1102, 1140, 1199, 1201, 1767, 1769, 1837, 1839], 'PDF': [653, 834, 952, 985, 1103, 1141, 1202, 1770, 1840], '(1253)': [656], 'Scholar);': [658], 'remodeling': [661], 'thought': [663, 1005], 'be': [665, 895, 1578, 1806, 2199, 2391, 3185], 'component': [667, 4112], 'activation': [670], 'repression': [672], 'receptors.': [675], 'Although': [676], 'important': [681, 1280, 2591, 3894], 'activity,': [684], 'it': [685], 'possible': [687], 'mechanisms,': [690], 'subcellular': [694], 'or': [701, 1779, 2428, 2954, 2994, 3424, 3621, 3917, 3935, 4074, 4212], 'ligand,': [704, 1786, 2238, 2607, 2867, 3156, 4046], 'may': [705, 1805, 3307], 'contribute': [706], 'regulation': [708], 'TR': [710], 'activity.': [712], 'connection,': [715], 'steroid': [716], 'glucocorticoid': [722], '(8Htun': [723], 'Barsony': [725], 'Renyi': [727], 'I.': [728], 'Gould': [729], 'D.J.': [730], 'Hager': [731, 801, 1188, 1756, 1826, 2029, 2131, 3995], 'G.L.': [732, 802, 1189, 1757, 1827, 2030, 2132, 3996], '4845-4850Crossref': [742], '(326)': [745], '9Govindan': [748], 'M.V.': [749], 'Devic': [750], 'M.': [751, 770, 798, 822, 825, 924, 939, 1440, 2045, 3255, 3367, 4011], 'Green': [752], 'Gronemeyer': [754], 'Chambon': [756], 'P.': [757, 818, 850, 914, 922, 3249, 3361], 'Nucleic': [758], 'Acids': [759], '1985;': [761], '13:': [762, 806], '8293-8304Crossref': [763], '(55)': [766], '10Papamichail': [769], 'Tsokos': [771], 'Tsawdaroglou': [773], 'Sekeris': [775], 'C.E.': [776], 'Exp.': [777], 'Cell': [778], '1980;': [780], '125:': [781], '490-493Crossref': [782], '(53)': [785], 'Scholar),': [787, 839, 865, 1144], 'progesterone': [788, 3275, 3353], '(11Lim': [789], 'C.S.': [790], 'Baumann': [791], 'C.T.': [792], 'Htun': [793, 2120], 'Xian': [795], 'W.': [796], 'Irie': [797], 'Smith': [799, 2050, 4016], 'C.L.': [800, 2051, 4017], 'Mol.': [803, 855, 958, 993, 2031, 2054, 2133, 3997, 4020], 'Endocrinol.': [804, 857, 960, 994, 2055, 4021], '366-375Crossref': [807], '(123)': [810], '12Guiochon-Mantel': [813], 'Loosfelt': [815, 3252, 3364], 'Lescop': [817, 3248, 3360], 'Sar': [819], 'Atger': [821], 'Perrot-': [823], 'Applanat': [824], 'Milgrom': [826, 3243, 3256, 3368], 'E.': [827, 1130, 3257, 3369], '1989;': [829], '57:': [830], '1147-1154Abstract': [831], '(242)': [837], 'androgen': [841], '(13Georget': [843], 'V.': [844], 'Lobaccaro': [845], 'J.M.': [846], 'Terouanne': [847], 'B.': [848, 918, 1432], 'Mangeat': [849], 'Nicolas': [851], 'J.C.': [852], 'Sultan': [853], 'C.': [854, 920, 2212], '129:': [859], '17-26Crossref': [860], '(158)': [863], 'at': [867, 2470, 3005, 3299, 3541], 'least': [868, 3300], 'partially': [869], 'translocate': [877, 3486], 'into': [878, 1858, 2093, 2437, 2556, 2630, 2964, 3121, 3280, 3355], 'hormone.': [885, 1306], 'their': [887], 'states,': [889], 'believed': [893, 2389], 'associated': [896, 2392, 2780, 4071, 4108], 'chaperone': [901], 'proteins': [902, 909, 1551, 2781], 'cytoplasm,': [905], 'heat': [907], 'shock': [908], '70': [910], '90': [912], '(14Lefebvre': [913], 'Danze': [915], 'P.M.': [916, 1480, 1523], 'Sablonniere': [917], 'Richard': [919], 'Formstecher': [921], 'Dautrevaux': [923], 'Biochemistry.': [925], '1988;': [926], '27:': [927], '9186-9994Crossref': [928], '(30)': [931], '15Housley': [934], 'P.R.': [935], 'Sanchez': [936], 'E.R.': [937], 'Danielsen': [938], 'Ringold': [940], 'G.M.': [941], 'Pratt': [942, 975, 1131], 'W.B.': [943, 957, 976, 1132], 'Biol.': [945, 978, 1096, 1134, 1193, 1761, 1831, 2032, 2134, 3998], 'Chem.': [946, 979, 1097, 1135, 1194, 1762, 1832], '1990;': [947, 961, 1136], '265:': [948, 1137], '12778-12781Abstract': [949], '16Pratt': [956], '74:': [962], 'C69-C76Crossref': [963], '(116)': [966], '17Hutchison': [969], 'K.A.': [970], 'Dittmar': [971], 'K.D.': [972], 'Czar': [973], '1994;': [980], '269:': [981], '5043-5049Abstract': [982], '18Johnson': [989], 'J.L.': [990], 'Toft': [991], 'D.O.': [992], '1995;': [995, 1444, 1490, 1533], '670-678Crossref': [997], '(211)': [1000], 'It': [1003], 'critical': [1010], 'receptor.The': [1019], 'has': [1024, 1688, 2919, 3340], 'been': [1025, 1259, 1689, 3341], 'characterized': [1026], 'cell': [1029, 3123], 'fractionation': [1030], 'indirect': [1032], 'immunofluorescence': [1033], 'approaches.': [1034], 'using': [1036, 1264], 'techniques,': [1038], 'completely': [1043, 3144, 4095], 'nucleus,': [1046, 1631, 2558, 2840, 4099], 'ligand': [1054, 1122, 1246, 1519, 2012, 2290, 2511, 3459, 3832, 4124], '(19Samuels': [1055], 'H.H.': [1056], 'J.S.': [1058], 'Cintron': [1059], 'Science.': [1061], '1973;': [1062], '181:': [1063], '1253-1256Crossref': [1064], '(121)': [1067], '20Oppenheimer': [1070], 'J.H.': [1071], 'Schwartz': [1072], 'H.L.': [1073], 'Surks': [1074], 'M.I.': [1075], 'Commun.': [1078], '1975;': [1079, 1098], '2:': [1080], '309-325Crossref': [1081], '(56)': [1084], '21Spindler': [1087], 'B.J.': [1088], 'MacLeod': [1089], 'K.M.': [1090], 'Ring': [1091], 'Baxter': [1093], 'J.D.': [1094], '250:': [1099], '4113-4119Abstract': [1100], 'Since': [1107], 'will': [1110], 'bind': [1111, 1295, 2355], 'recognition': [1114], 'sites': [1115], '(22Dalman': [1123], 'F.C.': [1124], 'Koenig': [1125], 'Perdew': [1127], 'G.H.': [1128], 'Massa': [1129], '3615-3618Abstract': [1138], 'prevailing': [1146], 'model': [1147], 'holds': [1148], 'constitutive': [1151], 'association': [1152, 3979, 4141], 'compartment': [1156], 'due': [1158, 1807], 'Conversely,': [1164], 'an': [1165, 2015, 2065, 2173, 2590, 2902, 3784, 3876, 4110, 4160], 'earlier': [1166], 'study': [1167, 1362], 'GFP': [1170, 1265, 1374, 1389, 1547, 1566, 2974, 4192], 'chimera': [1171], 'identified': [1174], 'significant': [1176, 1323, 3809], 'pool': [1177], '(23Zhu': [1184, 1752, 1822], 'X.': [1185, 1753, 1823], 'Hanover': [1186, 1754, 1824], 'J.A.': [1187, 1755, 1825], 'Cheng': [1190, 1758, 1828], 'S.-Y.': [1191, 1759, 1829], '273:': [1196, 1764, 1834], '27058-27063Abstract': [1197, 1765, 1835], '(100)': [1205, 1773, 1843], 'To': [1208, 1622, 2101, 2828, 3316, 3904], 'examine': [1209], 'potential': [1211], 'roles': [1212, 1281, 3895], 'functions': [1216], 'on': [1217, 1997, 2670, 2699, 2728, 2782, 3171, 3204, 3234, 3434, 3665, 3677, 3692, 3798], 'examined': [1225, 2277], 'battery': [1234], 'mutants,': [1237], 'functions,': [1244], 'binding,': [1247, 1249, 1520], 'homodimerization,': [1250], '(N-CoR)': [1254], 'interaction.': [1255], 'These': [1256, 2577, 2914, 3770], 'performed': [1260], 'cells': [1263, 1599, 1744, 1879, 3419, 3474, 3518, 3568, 3582, 3599, 3638, 3643, 3909, 4054, 4166], 'chimeras.': [1266], 'Our': [1267, 3291], 'suggest': [1269, 2397, 2579, 3297], 'heterodimerization': [1271, 3034, 3233], 'RXR': [1273, 2669, 2676, 3049, 3065, 3080, 3117, 3296, 3622, 3891, 3916, 3936, 3955], 'interaction': [1275, 1417], 'ligand-independent': [1284], 'retention': [1286, 3071], 'particular,': [1290], 'mutants': [1292, 1398, 1505, 2284], 'cannot': [1294], 'localization': [1301, 1901, 2411, 2479, 2597, 2938, 3014, 3041, 3085, 3236, 3550], 'Furthermore,': [1307], 'ablation': [1308], 'DNA-binding': [1311, 1458, 2349], 'capacity': [1312], 'does': [1315, 2498], 'prevent': [1317], 'its': [1318, 1416, 3155], 'accumulation.': [1320], 'Whereas': [1321], 'fraction': [1324], 'likely': [1329, 2588], 'bound': [1330], 'hormone,': [1337], 'conclude': [1339], 'formation': [1342], 'multifactor': [1344], 'complexes': [1345], 'heterodimer': [1347], 'partners': [1348], 'primarily': [1352], 'responsible': [1353], 'accumulation': [1356], 'receptor.RESULTSTo': [1361], 'generated': [1372, 1550], 'fusion': [1375, 1548, 1567, 2975, 3674], 'N': [1378], 'terminus': [1379], '(GFP-TRβ;': [1383], 'Fig.': [1384, 2210, 3091], '1': [1385, 3588, 3614], 'A).': [1386, 2086], 'addition,': [1388, 1560, 1680, 2064, 3112, 3197, 3416], 'were': [1391, 2679, 2708, 2738, 2833, 2962, 3475, 3519, 3639, 3910, 4167], 'made': [1392], 'series': [1395], '(Fig.1': [1399], 'B).': [1400, 1621, 2100, 2913], 'GFP-TRβ-AHT': [1401, 2536, 2554, 2621, 2650, 2660, 2678, 2689, 2707, 2718, 2737, 2748, 2764, 3102, 3129, 3167, 3191, 3209, 3294, 3799, 3821, 3834], 'contains': [1402, 1453, 2342], 'three': [1403], 'point': [1404], 'mutations': [1405], 'hinge': [1408], 'region': [1409], '(A223G,': [1410], 'H224G,': [1411], 'T227G)': [1413], 'abrogate': [1415], '(32Horlein': [1423], 'A.J.': [1424], 'Naar': [1425], 'A.M.': [1426], 'Heinzel': [1427], 'T.': [1428], 'Torchia': [1429], 'Gloss': [1431], 'Kurokawa': [1433], 'Ryan': [1435], 'Kamei': [1437], 'Soderstrom': [1439], '377:': [1445], '397-404Crossref': [1446], '(1695)': [1449], 'GFP-TRβ-127': [1452, 2337, 2367, 2420, 2882], 'mutation': [1455], 'domain': [1459, 2350], '(C127A)': [1460], 'destroys': [1462], 'integrity': [1464], 'first': [1467], 'zinc': [1468, 2345], 'finger': [1469, 2346], 'prevents': [1471], 'from': [1474, 1506, 1684, 2908, 3487, 3842, 4062, 4097], 'vitro': [1478], '(33Yen': [1479, 1522], 'Wilcox': [1481, 1524], 'E.C.': [1482, 1525], 'Hayashi': [1483, 1526], 'Refetoff': [1485, 1528], 'Chin': [1487, 1530], 'W.W.': [1488, 1531], 'Endocrinology.': [1489, 1532], '136:': [1491, 1534], '2845-2851Crossref': [1492, 1535], '(35)': [1495, 1538], 'GFP-TRβ-429': [1498, 2845, 2848, 2868, 2895, 2945], '(R429Q)': [1499], 'GFP-TRβ-345': [1501, 2418], '(G345R)': [1502], 'natural': [1504], 'patients': [1507], 'resistance': [1509], 'deficient': [1515], 'homodimerization': [1517, 2918], 'respectively': [1521], 'Western': [1541], 'blot': [1542], 'indicated': [1544, 4209], 'all': [1546, 4058], 'constructs': [1549], 'predicted': [1554, 3076, 3186], 'size': [1555], '(data': [1556, 1588, 1730], 'shown).': [1558, 1732, 2331, 4122], 'each': [1565, 1895, 2446, 2473, 2973, 3008, 3544, 3652, 4206, 4217], 'assayed': [1569], 'transient': [1571], 'cotransfection': [1572], 'similar': [1579, 2294, 2877, 4031], 'reported': [1582, 1690, 1747], 'previously': [1583, 3339], 'unfused': [1586, 3048, 3199], 'shown).Analysis': [1590], 'GFP-TRβ': [1596, 1627, 1636, 1658, 1681, 1729, 1850, 1866, 1959, 1961, 2069, 2076, 2091, 2107, 2149, 2181, 2244, 2265, 2298, 2447, 2513, 3324, 3392, 3408, 3439, 3453, 3482, 3498, 3513, 3560, 3597, 3629, 3697, 3913, 3947, 4093, 4106, 4152, 4156], 'majority': [1603], 'localized': [1606, 1660, 1972, 1984, 2538, 2796, 2818, 3103, 3391, 3708, 3755], 'T3': [1617, 1671, 2063, 2305, 2993, 3612, 3727], '(Fig.2,': [1618], 'quantitate': [1623, 2102], 'percentage': [1625, 1968, 1980, 2792, 2814, 3704, 3751], 'present': [1628], 'area-corrected': [1633], 'intensity': [1634, 1940, 2147, 2163, 2167, 2174, 2759], 'fluorescence': [1637, 4193], 'calculated': [1646], '(see': [1647], '"Experimental': [1648, 1908, 2486, 2768, 3021, 3538, 3557, 3579, 3647, 4180], 'Procedures").': [1649], 'From': [1650], 'analyses,': [1652], 'determined': [1654, 1868, 2450, 2977, 3655], '85–90%': [1656], '(Fig.': [1672, 1695, 2084, 2098, 2231, 2323, 2373, 2569, 2883, 2911, 3159, 3178, 3397, 3440, 3468, 3929, 3937, 4116], '2,': [1673, 1696], 'B,': [1676, 2309, 2327, 2656, 3400, 3851], 'TableI).': [1678], 'excluded': [1683], 'nucleoli,': [1686], 'B': [1699, 2571], '(8,': [1700], '11,': [1701], '13,': [1702], '27)).': [1703], 'The': [1704, 1793, 3649, 3668], 'observed': [1705, 1725, 2598, 3626], 'ratio': [1707], 'independent': [1709], 'amount': [1712, 1798, 3115, 3127], 'transfected,': [1715], 'indicating': [1716, 4065], 'expression': [1719, 3118], 'levels': [1720], 'did': [1721], 'impact': [1723], 'We': [1733, 4027], 'somewhat': [1736], 'lower': [1737], 'concentration': [1739], 'hormone-free': [1743], 'Zhu': [1749, 1819], 'et': [1750, 1820, 2121], 'al.': [1751, 1821, 2122], 'Scholar)': [1775, 3267], '(nuclear/cytoplasmic': [1776], '=': [1777, 3713, 3760], '1.5': [1778], '∼60%': [1780], 'nuclear);': [1781], 'results': [1788, 2396, 2578, 2915, 3218, 4032], 'complete': [1791], 'accord.': [1792], 'quantitative': [1794, 2268], 'difference': [1795], 'differences': [1809], 'experimental': [1811], 'conditions': [1812], 'Scholar).Figure': [1845], '2Intracellular': [1846], 'HeLa': [1852, 1859, 1878, 2422, 2438, 2623, 2631, 2682, 2711, 2741, 2949, 2965, 3479, 3493, 3515, 3517, 3642, 4165], 'cells.pEGFP-TRβ': [1853], '(100': [1854, 2432, 2626, 2959], 'ng)': [1855, 2627], 'transfected': [1857, 2436, 2629, 2963, 3120, 3520, 4168], 'laser-scanning': [1870, 2452, 2643, 2979, 4197], 'confocal': [1871, 2453, 2644, 2980, 4198], 'microscopy.': [1872, 2454, 2645, 2981, 4199], 'Representative': [1873, 2455, 2982], 'image': [1874, 1896, 1953, 2456, 2474, 2493, 2775, 2983, 3009, 3028, 3545, 3685, 4207], 'EGFP-TRβ': [1876], '(A)': [1883, 2987, 4184], '(B)': [1886, 2990, 4187], '10−6m': [1888, 1933, 2992, 3001, 3611, 4190], 'T3.Arrows': [1889], 'indicate': [1890, 2219], 'nucleoli.': [1891], 'Numbers': [1892, 2469, 3004, 3540], 'atbottom': [1893], 'represents': [1897, 2475, 3010], 'average': [1899, 2146, 2162, 2166, 2477, 2757, 3012, 3548], '(in': [1902], 'percent': [1903, 2481, 2761, 3016, 3552], 'total)': [1904, 2482, 2762, 3017, 3553], 'described': [1906, 2285, 2484, 2693, 2722, 2752, 2766, 3019, 3536, 3555, 3577, 3645, 3879, 4178], 'under': [1907, 2485, 2767, 3020, 3537, 3556, 3578, 4179], 'Procedures."': [1909, 3539, 3558, 3580, 3648], 'C': [1910, 2375, 2885, 3093, 3161, 3442], 'D,': [1912, 2377, 2695, 3444, 3596], 'representative': [1913, 2647, 2657], 'line': [1914, 2154, 2205, 2229], 'graphs': [1915], 'displaying': [1916], 'variation': [1918, 2217, 2242, 2258], 'pixel': [1920, 1939], 'intensities': [1921, 2182], 'across': [1922, 1941], 'nuclei': [1924, 3490, 3653, 3661, 4201], '(C)': [1928, 2997], '(D)': [1931], 'T3.': [1934, 2665, 4191], 'Values': [1935, 2754, 3748], 'represent': [1936, 1966, 1978, 2755, 2790, 2812, 3546, 3702, 3749], 'mean': [1938], 'graph.': [1943], 's.d.': [1944], 'S.D.View': [1947], 'Large': [1948, 2488, 2770, 3023, 3680, 4219], 'Image': [1949, 2489, 2771, 3024, 3681], 'Figure': [1950, 2490, 2772, 3025, 3682], 'ViewerDownload': [1951, 2491, 2773, 3026, 3683], 'Hi-res': [1952, 2492, 2774, 3027, 3684], 'Download': [1954, 2494, 2776, 3029, 3686], '(PPT)Table': [1955, 2777, 3687], 'IIntracellular': [1956], 'mutantsExpressed': [1962], 'receptorT3Average': [1963], '1-aAll': [1964], 'values': [1965, 1977, 2789, 2811], 'expressed': [1970, 1982, 2794, 2816, 3047, 3706, 3753], 'nucleus.S.D.%GFP-TRβ−88.92.3+88.74.5GFP-TRβ-345−83.57.4+89.64.2GFP-TRβ-127−76.23.3+80.72.9GFP-TRβ-AHT−4510+84.38.4GFP-TRβ-429−74.63.4+85.33.31-a': [1975], 'All': [1976, 2810], 'Open': [1988, 2822, 3764], 'table': [1989, 2823, 3765], 'new': [1992, 2826, 3768], 'tab': [1993, 2827, 3769], 'previous': [1995], 'intranuclear': [1999, 2016, 2066, 2104, 2269, 2318, 4133], 'estrogen': [2008, 3273, 3351, 3967, 3973], 'receptor,': [2009, 3074], 'addition': [2010, 2088, 2273, 2547, 3427, 3593, 3609, 3830], 'led': [2013, 3835], 'rearrangement': [2017, 2067], '(27Htun': [2021, 2123, 3987], 'Holth': [2023, 2125, 3989], 'L.T.': [2024, 2126, 3990], 'Walker': [2025, 2127, 3991], 'Davie': [2027, 2129, 3993], 'J.R.': [2028, 2130, 3994], '10:': [2035, 2137, 3261, 3373, 4001], '471-486Crossref': [2036, 2138, 4002], '(219)': [2039, 2141, 4005], '34Stenoien': [2042, 4008], 'Mancini': [2044, 2052, 4010, 4018], 'Patel': [2046, 4012], 'K.': [2047, 4013], 'Allegretto': [2048, 4014], 'E.A.': [2049, 4015], 'M.A.': [2053, 4019], '2000;': [2056, 4022], '14:': [2057, 4023], '518-534PubMed': [2058, 4024], 'Similarly,': [2061], 'upon': [2062, 2271], 'occurred.': [2070], 'organized': [2078], 'diffuse,': [2081], 'reticular': [2082], 'pattern': [2083, 2097], '2': [2085, 2099, 2211, 2232, 3574, 3605], 'Upon': [2087], 'redistributed': [2092, 3393], 'discrete': [2095], 'punctate': [2096], 'adopted': [2116, 2901], 'method': [2118], 'Briefly,': [2144], 'along': [2150, 2183], 'random': [2152], 'linear': [2153], 'determined.': [2156], 'Dividing': [2157], 'S.D.': [2159], 'yielded': [2168], 'coefficient': [2170, 2189, 2215, 2240, 2256], 'variation,': [2172, 2191], 'corrected': [2175], 'value': [2176], 'representing': [2177], 'range': [2179], 'line.': [2186], 'low': [2188], 'indicative': [2192], 'more': [2195, 2221, 2505, 4075], 'diffuse': [2196], 'distribution,': [2197], 'would': [2198, 2218, 3184], 'represented': [2200, 2226], 'relatively': [2203], 'smooth': [2204], 'profile,': [2206], 'shown': [2208, 3269, 3342, 3676, 3828], 'high': [2214, 4047], 'focal': [2222], 'uneven': [2228], 'profile': [2230], 'D).': [2233], '0.11': [2246], '±': [2247, 2262], '0.01,': [2248], 'increased': [2259, 3135], '0.25': [2261], '0.07.': [2263], 'Therefore,': [2264, 4123], 'undergoes': [2266], 'redistribution': [2270, 3437, 3627, 3810, 3838, 3945], 'T3.We': [2275], 'then': [2276, 3920], 'above.': [2286, 2694, 2753], 'GFP-TRβ-345,': [2287], 'binds': [2289], 'poorly,': [2291], 'exhibited': [2292], '(Fig.3,': [2306], 'Table': [2311, 2379, 2875, 2887, 3181, 3213, 3446, 3853, 3886, 3933], 'I)': [2312], 'no': [2314, 3169, 3202, 3432], 'change': [2315, 4130], '3,': [2324, 2374], 'data': [2329, 4120], 'Next,': [2332], 'studied.': [2339, 2847, 3801], 'disrupted': [2344], 'unable': [2353], 'DNA.': [2356], '∼80%': [2365], 'I).': [2380, 2888], 'Even': [2381], 'though': [2382], 'DNA,': [2394], 'plays': [2402], 'minor': [2405, 2922], 'TRβ.Figure': [2414, 2941], '3Intracellular': [2415], 'cells.': [2423, 2624, 3516], 'pEGFP-TRβ-345': [2424], '(A': [2425, 2460, 2951], 'B)': [2427, 2953, 4044], 'pEGFP-TRβ-127': [2429], '(C': [2430, 2956], 'andD)': [2431, 2466], 'ng': [2433, 2960, 3523, 4171], 'each)': [2434, 2961], 'C)': [2462], '(B': [2465], '10−6mT3.': [2468, 2655, 3595], 'bottom': [2471, 3006, 3542, 4118], '(as': [2480, 2760, 3015, 3551], 'Procedures."View': [2487, 2769, 3022], '(PPT)Surprisingly,': [2495], 'GFP-TRβ-AHT,': [2496, 3054], 'interact': [2500, 3193], 'N-CoR,': [2502], 'significantly': [2504], '(Fig.4': [2514, 3210], 'Tables': [2517, 2573], 'I': [2518, 2543, 2574], 'andII).': [2519, 2544], 'Quantitative': [2520], 'analyses': [2521], 'less': [2531], '50%': [2533], '(Tables': [2542], 'However,': [2545, 2602, 2889, 4080], 'after': [2546, 3327, 3425, 3607, 3630, 3673, 4081, 4186], 'substantial': [2551], 'portion': [2552, 3302, 4102], 'translocated': [2555, 2896], 'resulting': [2559], '∼85%': [2561], 'localizing': [2565], '4': [2570, 3092, 3179, 3882], 'II).': [2576, 3137, 3854], 'that,': [2580], 'dispensable': [2611], 'nucleus.Figure': [2617, 4150], '4Intracellular': [2618], 'pEGFP-TRβ-AHT': [2625], 'followed': [2641, 2691, 2720, 2750, 4195], 'A,': [2646, 3559], 'example': [2648, 2658], 'C,': [2666], 'effect': [2667, 2696, 2724, 3170, 3203, 3433, 3794], 'GFP-TRβ-AHT.': [2675, 2704, 2733, 3090], 'coexpressed': [2680, 2709, 2739], 'above.E,': [2723], 'IIEffect': [2778], 'GFP-TRβ-AHTExpressed': [2787, 3699], 'receptorRXRAverage2-aAll': [2788], 'nucleus.S.D.μg%GFP-TRβ-AHT': [2799], '−': [2800, 2808, 3717, 3738], 'T34510GFP-TRβ-AHT': [2801], '+': [2802, 2804, 2806, 3720, 3722, 3724, 3726, 3728, 3730, 3732, 3734, 3736, 3740, 3742, 3744, 3746], 'T384.38.4GFP-TRβ-AHT': [2803], 'N-CoR42.46GFP-TRβ-AHT': [2805], 'TRβ48.57GFP-TRβ-AHT': [2807], 'T30.0155.83.30.1623.81.067.24.32-a': [2809], 'investigate': [2829, 3031], 'if': [2830], 'additional': [2831], 'required': [2834, 2934], 'retaining': [2836], 'selectively': [2849], 'forms': [2850], 'heterodimers': [2851], '(RXR)': [2857], 'homodimerization.': [2862], '∼75%': [2870], '(Fig.5': [2872], 'I),': [2876], 'seen': [2880, 3219], '3': [2884], 'indistinguishable': [2907], '5': [2912, 3884], '5Intracellular': [2942], 'GFP-RXR': [2947, 3140], 'cells.pEGFP-TRβ-429': [2950], 'pEGFP-RXR': [2955], 'D)': [2958], 'presence(D)': [2999], '9-cis-retinoic': [3002, 3157], 'acid.': [3003], '(PPT)To': [3030], 'further': [3032, 3228, 3788], 'whether': [3033], 'played': [3035, 3893], 'ligand.': [3063], 'If': [3064], 'coexpression': [3078], 'should': [3081], 'increase': [3082], 'predominantly': [3088], 'demonstrates': [3094], 'indeed': [3098], 'case': [3100], 'when': [3107], 'cotransfected': [3108, 3911], 'RXR.': [3110], 'vector': [3119], 'increased,': [3125], 'retained': [3130], 'also': [3134, 3308, 4138], '(Table': [3136], 'As': [3138, 3827], 'expected,': [3139], 'almost': [3143], 'acid': [3158], '5,': [3160], 'andD).': [3162], 'Coexpression': [3163, 3616, 3925], 'Dand': [3180], 'II)': [3182], 'inability': [3189], 'N-CoR.': [3195], 'coexpressing': [3198], 'E': [3211, 3931], 'II),': [3214, 3887], 'consistent': [3215], 'heterodimer-specific': [3222], 'GFP-TRβ-429.': [3223], 'Taken': [3224], 'together,': [3225], 'underscore': [3229], 'TRβ.Previous': [3240], 'co-workers': [3245], '(29Guiochon-Mantel': [3246, 3358], 'Christin-Maitre': [3250, 3362], 'Perrot-Applanat': [3254, 3366], 'EMBO': [3258, 3370], '1991;': [3260, 3372], '3851-3859Crossref': [3262, 3374], '(246)': [3265, 3377], 'actively': [3278], 'transported': [3279], 'return': [3284], 'passive': [3289], 'diffusion.': [3290], 'shuttle': [3309, 3501], 'cytoplasm.': [3315, 3414], 'confirm': [3317, 3905], 'hypothesis,': [3319], 'treatment': [3328, 3383, 3417, 3534, 3563, 3631, 4086, 4188], 'sodium': [3330, 3385, 3429, 3532, 3565, 3571, 3585, 3602, 3633, 3690, 3796, 3806, 3860, 3923, 3943], 'azide,': [3331, 3386, 3430, 3807, 3861], 'depletes': [3333], 'stores': [3335], 'block': [3344], 'ATP-dependent': [3346, 3877], 'uptake': [3347], 'After': [3380], '2-h': [3382], '∼10%': [3387], '6,A': [3398], 'TableIII),': [3402], 'demonstrating': [3403, 3448, 3869], 'subpopulation': [3406], 'either': [3422, 3618, 3915, 3927], 'before': [3423, 4183], '6,': [3441], 'III)': [3447, 3934], 'population': [3451], 'unaffected': [3457], 'binding.': [3460], 'observation': [3462], 'confirmed': [3464], '6': [3469, 3930, 3938], 'G).': [3470], 'Here,': [3471], 'GFP-TRβ-expressing': [3472, 4053], 'NIH3T3': [3473, 3489, 3637], 'fused': [3476, 3640], 'nonexpressing': [3478], 'nuclei,': [3494, 4064], 'again': [3495, 3868, 3950], 'confirming': [3496], 'compartments.Figure': [3508], '6Nuclear': [3509], '100': [3522, 4170], 'pEGFP-TRβ': [3525, 4173], 'subsequently': [3527], 'depleted': [3528], 'azide': [3533, 3572, 3586, 3603, 3691, 3723, 3731, 3735, 3745, 3797], 'prior': [3561, 3590], 'azide.': [3566, 3634, 3924], 'B,GFP-TRβ-expressing': [3567], 'treated': [3569, 3583, 3600, 3921], 'h': [3575, 3589, 3606], 'C,GFP-TRβ-expressing': [3581], 'expressing': [3598], 'h.': [3615], '(E)': [3620], '(F)': [3623], 'blocks': [3624], 'G,': [3635], 'pEGFP-TRb-expressing': [3636], 'identity': [3650], 'DAPI': [3657], 'staining': [3658], '(left)': [3662], 'labeled': [3664], 'figure.': [3667], 'EGFP-TRb': [3672], 'right.View': [3679], 'IIIEffect': [3688], 'receptorAverage': [3700], '3-aValues': [3701], 'nucleus.S.D.Cytoplasmic': [3711], '3-bCytoplasmic': [3712], '100-average': [3714, 3761], 'intensity.%GFP-TRβ': [3716], 'T388.92.311.1GFP-TRβ': [3718], 'induced88.74.511.3GFP-TRβ': [3719], 'azide80.63.819.4GFP-TRβ': [3721], 'T378.24.221.8GFP-TRβ': [3725], 'Azide79.82.120.2GFP-TRβ': [3729], 'N-CoR90.65.19.4GFP-TRβ': [3733], 'RXR90.35.99.7GFP-TRβ-AHT': [3737], 'T3451055GFP-TRβ-AHT': [3739], 'T384.38.415.7GFP-TRβ-AHT': [3741], 'azide24.28.175.8GFP-TRβ-AHT': [3743], 'T330.310.669.73-a': [3747], 'nucleus.3-b': [3758], 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'remained': [4107], 'extraction-resistant': [4111], '7B,': [4117], 'panel,': [4119], 'induces': [4128], 'but': [4137, 4153], 'increases': [4139], 'nonchromatin': [4146], '7Ligand-bound': [4151], 'insoluble': [4161], 'com': [4163], 'ponent.': [4164], 'sequentially': [4175], 'extracted': [4176], 'Procedures"': [4181], 'DAPI-stained': [4200], '(right)': [4202], 'included': [4204], 'following': [4216], 'treatment.View': [4218]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2088134840', 'counts_by_year': [{'year': 2024, 'cited_by_count': 1}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 3}, {'year': 2020, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 7}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 8}, {'year': 2012, 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