Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2088091011', 'doi': 'https://doi.org/10.1371/journal.pcbi.1003831', 'title': 'The Structural Basis of ATP as an Allosteric Modulator', 'display_name': 'The Structural Basis of ATP as an Allosteric Modulator', 'publication_year': 2014, 'publication_date': '2014-09-11', 'ids': {'openalex': 'https://openalex.org/W2088091011', 'doi': 'https://doi.org/10.1371/journal.pcbi.1003831', 'mag': '2088091011', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25211773', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/4161293'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pcbi.1003831', 'pdf_url': 'https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003831&type=printable', 'source': {'id': 'https://openalex.org/S86033158', 'display_name': 'PLoS Computational Biology', 'issn_l': '1553-734X', 'issn': ['1553-734X', '1553-7358'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316756', 'host_organization_name': 'International Society for Computational Biology', 'host_organization_lineage': ['https://openalex.org/P4310316756'], 'host_organization_lineage_names': ['International Society for Computational Biology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'doaj', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003831&type=printable', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5049338114', 'display_name': 'Shaoyong Lu', 'orcid': 'https://orcid.org/0000-0002-1334-6292'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Shaoyong Lu', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065887901', 'display_name': 'Wenkang Huang', 'orcid': 'https://orcid.org/0000-0002-8028-5047'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Wenkang Huang', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021252906', 'display_name': 'Qi Wang', 'orcid': 'https://orcid.org/0000-0001-9006-9914'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Qi Wang', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5019773375', 'display_name': 'Qiancheng Shen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Qiancheng Shen', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5100702790', 'display_name': 'Shuai Li', 'orcid': 'https://orcid.org/0000-0001-5784-0949'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Shuai Li', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5025357844', 'display_name': 'Ruth Nussinov', 'orcid': 'https://orcid.org/0000-0002-8115-6415'}, 'institutions': [{'id': 'https://openalex.org/I16391192', 'display_name': 'Tel Aviv University', 'ror': 'https://ror.org/04mhzgx49', 'country_code': 'IL', 'type': 'education', 'lineage': ['https://openalex.org/I16391192']}, {'id': 'https://openalex.org/I114662689', 'display_name': 'Leidos (United States)', 'ror': 'https://ror.org/012cvds63', 'country_code': 'US', 'type': 'company', 'lineage': ['https://openalex.org/I114662689']}, {'id': 'https://openalex.org/I4210140884', 'display_name': 'National Cancer Institute', 'ror': 'https://ror.org/040gcmg81', 'country_code': 'US', 'type': 'government', 'lineage': ['https://openalex.org/I1299022934', 'https://openalex.org/I1299303238', 'https://openalex.org/I4210140884']}], 'countries': ['IL', 'US'], 'is_corresponding': True, 'raw_author_name': 'Ruth Nussinov', 'raw_affiliation_strings': ['Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, National Cancer Institute, Frederick, Maryland, United States of America', 'Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Sackler Institute of Molecular Medicine, Tel Aviv University, Tel Aviv, Israel'], 'affiliations': [{'raw_affiliation_string': 'Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Sackler Institute of Molecular Medicine, Tel Aviv University, Tel Aviv, Israel', 'institution_ids': ['https://openalex.org/I16391192']}, {'raw_affiliation_string': 'Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory, National Cancer Institute, Frederick, Maryland, United States of America', 'institution_ids': ['https://openalex.org/I114662689', 'https://openalex.org/I4210140884']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5100409987', 'display_name': 'Jian Zhang', 'orcid': 'https://orcid.org/0000-0002-6558-791X'}, 'institutions': [{'id': 'https://openalex.org/I183067930', 'display_name': 'Shanghai Jiao Tong University', 'ror': 'https://ror.org/0220qvk04', 'country_code': 'CN', 'type': 'education', 'lineage': ['https://openalex.org/I183067930']}], 'countries': ['CN'], 'is_corresponding': True, 'raw_author_name': 'Jian Zhang', 'raw_affiliation_strings': ['Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China'], 'affiliations': [{'raw_affiliation_string': 'Department of Pathophysiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai JiaoTong University, School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}, {'raw_affiliation_string': 'Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China', 'institution_ids': ['https://openalex.org/I183067930']}]}], 'countries_distinct_count': 3, 'institutions_distinct_count': 4, 'corresponding_author_ids': ['https://openalex.org/A5049338114', 'https://openalex.org/A5065887901', 'https://openalex.org/A5021252906', 'https://openalex.org/A5019773375', 'https://openalex.org/A5100702790', 'https://openalex.org/A5025357844', 'https://openalex.org/A5100409987'], 'corresponding_institution_ids': ['https://openalex.org/I183067930', 'https://openalex.org/I183067930', 'https://openalex.org/I183067930', 'https://openalex.org/I183067930', 'https://openalex.org/I183067930', 'https://openalex.org/I16391192', 'https://openalex.org/I114662689', 'https://openalex.org/I4210140884', 'https://openalex.org/I183067930'], 'apc_list': {'value': 2655, 'currency': 'USD', 'value_usd': 2655, 'provenance': 'doaj'}, 'apc_paid': {'value': 2655, 'currency': 'USD', 'value_usd': 2655, 'provenance': 'doaj'}, 'fwci': 4.528, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 81, 'citation_normalized_percentile': {'value': 0.881649, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 97, 'max': 98}, 'biblio': {'volume': '10', 'issue': '9', 'first_page': 'e1003831', 'last_page': 'e1003831'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure Prediction and Analysis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10044', 'display_name': 'Protein Structure Prediction and Analysis', 'score': 0.9996, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10532', 'display_name': 'Fluorescent Chemosensors for Ion Detection and Bioimaging', 'score': 0.997, 'subfield': {'id': 'https://openalex.org/subfields/1607', 'display_name': 'Spectroscopy'}, 'field': {'id': 'https://openalex.org/fields/16', 'display_name': 'Chemistry'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10521', 'display_name': 'Ribosome Structure and Translation Mechanisms', 'score': 0.9968, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/allosteric-enzyme', 'display_name': 'Allosteric enzyme', 'score': 0.82583183}, {'id': 'https://openalex.org/keywords/adenosine-triphosphate', 'display_name': 'Adenosine triphosphate', 'score': 0.73623097}, {'id': 'https://openalex.org/keywords/proteins', 'display_name': 'Proteins', 'score': 0.45176}], 'concepts': [{'id': 'https://openalex.org/C166342909', 'wikidata': 'https://www.wikidata.org/wiki/Q845326', 'display_name': 'Allosteric regulation', 'level': 3, 'score': 0.98625004}, {'id': 'https://openalex.org/C109964505', 'wikidata': 'https://www.wikidata.org/wiki/Q3321436', 'display_name': 'Allosteric enzyme', 'level': 4, 'score': 0.82583183}, {'id': 'https://openalex.org/C2779564974', 'wikidata': 'https://www.wikidata.org/wiki/Q80863', 'display_name': 'Adenosine triphosphate', 'level': 2, 'score': 0.73623097}, {'id': 'https://openalex.org/C12554922', 'wikidata': 'https://www.wikidata.org/wiki/Q7100', 'display_name': 'Biophysics', 'level': 1, 'score': 0.5624675}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.41923553}, {'id': 'https://openalex.org/C112243037', 'wikidata': 'https://www.wikidata.org/wiki/Q22327117', 'display_name': 'ATP synthase', 'level': 3, 'score': 0.41286647}, {'id': 'https://openalex.org/C107824862', 'wikidata': 'https://www.wikidata.org/wiki/Q616005', 'display_name': 'Binding site', 'level': 2, 'score': 0.4103799}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.39736873}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33023894}, {'id': 'https://openalex.org/C181199279', 'wikidata': 'https://www.wikidata.org/wiki/Q8047', 'display_name': 'Enzyme', 'level': 2, 'score': 0.25450987}], 'mesh': [{'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D004798', 'descriptor_name': 'Enzymes', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': True}, {'descriptor_ui': 'D000495', 'descriptor_name': 'Allosteric Site', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001419', 'descriptor_name': 'Bacteria', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005658', 'descriptor_name': 'Fungi', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D056004', 'descriptor_name': 'Molecular Dynamics Simulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011506', 'descriptor_name': 'Proteins', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013816', 'descriptor_name': 'Thermodynamics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pcbi.1003831', 'pdf_url': 'https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003831&type=printable', 'source': {'id': 'https://openalex.org/S86033158', 'display_name': 'PLoS Computational Biology', 'issn_l': '1553-734X', 'issn': ['1553-734X', '1553-7358'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316756', 'host_organization_name': 'International Society for Computational Biology', 'host_organization_lineage': ['https://openalex.org/P4310316756'], 'host_organization_lineage_names': ['International Society for Computational Biology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://doaj.org/article/f0b1556288614cbca5101c9b7b70b4cf', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306401280', 'display_name': 'DOAJ (DOAJ: Directory of Open Access Journals)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': None, 'host_organization_name': None, 'host_organization_lineage': [], 'host_organization_lineage_names': [], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc4161293', 'pdf_url': 'https://europepmc.org/articles/pmc4161293?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161293', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25211773', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pcbi.1003831', 'pdf_url': 'https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1003831&type=printable', 'source': {'id': 'https://openalex.org/S86033158', 'display_name': 'PLoS Computational Biology', 'issn_l': '1553-734X', 'issn': ['1553-734X', '1553-7358'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316756', 'host_organization_name': 'International Society for Computational Biology', 'host_organization_lineage': ['https://openalex.org/P4310316756'], 'host_organization_lineage_names': ['International Society for Computational Biology'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Affordable and clean energy', 'id': 'https://metadata.un.org/sdg/7', 'score': 0.88}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 74, 'referenced_works': ['https://openalex.org/W1908759766', 'https://openalex.org/W1968984443', 'https://openalex.org/W1969542803', 'https://openalex.org/W1969836007', 'https://openalex.org/W1974590528', 'https://openalex.org/W1975292161', 'https://openalex.org/W1975757940', 'https://openalex.org/W1976499671', 'https://openalex.org/W1978329718', 'https://openalex.org/W1983550904', 'https://openalex.org/W1989723686', 'https://openalex.org/W1990347893', 'https://openalex.org/W1992958350', 'https://openalex.org/W1995254028', 'https://openalex.org/W1999086038', 'https://openalex.org/W2003002245', 'https://openalex.org/W2005490060', 'https://openalex.org/W2011847686', 'https://openalex.org/W2014252415', 'https://openalex.org/W2015807753', 'https://openalex.org/W2022870456', 'https://openalex.org/W2030683839', 'https://openalex.org/W2031430816', 'https://openalex.org/W2037687436', 'https://openalex.org/W2039781258', 'https://openalex.org/W2041205020', 'https://openalex.org/W2042906495', 'https://openalex.org/W2049786263', 'https://openalex.org/W2051974567', 'https://openalex.org/W2057927368', 'https://openalex.org/W2058206411', 'https://openalex.org/W2061772446', 'https://openalex.org/W2062884696', 'https://openalex.org/W2063241473', 'https://openalex.org/W2063919290', 'https://openalex.org/W2067174909', 'https://openalex.org/W2069123478', 'https://openalex.org/W2069893750', 'https://openalex.org/W2076790509', 'https://openalex.org/W2088443855', 'https://openalex.org/W2090227348', 'https://openalex.org/W2090763498', 'https://openalex.org/W2094632840', 'https://openalex.org/W2096539359', 'https://openalex.org/W2097382368', 'https://openalex.org/W2105668062', 'https://openalex.org/W2105711740', 'https://openalex.org/W2106140689', 'https://openalex.org/W2110899053', 'https://openalex.org/W2114577844', 'https://openalex.org/W2119392004', 'https://openalex.org/W2122263221', 'https://openalex.org/W2124042056', 'https://openalex.org/W2125299915', 'https://openalex.org/W2128716813', 'https://openalex.org/W2129418158', 'https://openalex.org/W2130479394', 'https://openalex.org/W2134329421', 'https://openalex.org/W2142868265', 'https://openalex.org/W2143210482', 'https://openalex.org/W2149371927', 'https://openalex.org/W2153630542', 'https://openalex.org/W2156346381', 'https://openalex.org/W2157292761', 'https://openalex.org/W2157605186', 'https://openalex.org/W2159884214', 'https://openalex.org/W2161732286', 'https://openalex.org/W2163915395', 'https://openalex.org/W2169750653', 'https://openalex.org/W2170968124', 'https://openalex.org/W2172114459', 'https://openalex.org/W2178587031', 'https://openalex.org/W4285719527', 'https://openalex.org/W4297811789'], 'related_works': ['https://openalex.org/W5024670', 'https://openalex.org/W4220959342', 'https://openalex.org/W3164888202', 'https://openalex.org/W2751232480', 'https://openalex.org/W2463850709', 'https://openalex.org/W2333603516', 'https://openalex.org/W2088091011', 'https://openalex.org/W2049682677', 'https://openalex.org/W2034301964', 'https://openalex.org/W1982170406'], 'abstract_inverted_index': {"Adenosine-5'-triphosphate": [0], '(ATP)': [1], 'is': [2, 28, 161], 'generally': [3], 'regarded': [4], 'as': [5], 'a': [6, 171], 'substrate': [7, 96, 116, 133], 'for': [8, 70, 192], 'energy': [9], 'currency': [10], 'and': [11, 43, 56, 61, 82, 115, 123, 158], 'protein': [12], 'modification.': [13], 'Recent': [14], 'findings': [15], 'uncovered': [16], 'the': [17, 48, 54, 62, 86, 95, 104, 112, 132, 139, 143, 147, 165, 175], 'allosteric': [18, 87, 114, 144, 148, 154, 157, 189], 'function': [19], 'of': [20, 34, 39, 108, 119, 136, 168, 178, 187], 'ATP': [21, 40, 50, 71, 77, 109, 128, 140, 151, 188], 'in': [22, 41, 53, 59, 85, 94, 126, 194], 'cellular': [23], 'signal': [24], 'transduction': [25], 'but': [26, 90], 'little': [27], 'understood': [29], 'about': [30], 'this': [31], 'critical': [32], 'behavior': [33], 'ATP.': [35, 179], 'Through': [36], 'extensive': [37], 'analysis': [38], 'solution': [42, 127], 'proteins,': [44], 'we': [45], 'found': [46], 'that': [47, 125], 'free': [49], 'can': [51], 'exist': [52], 'compact': [55, 81], 'extended': [57, 83, 92], 'conformations': [58, 84, 93], 'solution,': [60], 'two': [63], 'different': [64], 'conformational': [65], 'characteristics': [66], 'may': [67], 'be': [68], 'responsible': [69, 191], 'to': [72, 111, 131, 152], 'exert': [73], 'distinct': [74, 105], 'biological': [75, 195], 'functions:': [76], 'molecules': [78, 141], 'adopt': [79], 'both': [80], 'binding': [88, 97, 110, 117, 134, 145], 'sites': [89, 118, 135, 160], 'conserve': [91], 'sites.': [98], 'Nudged': [99], 'elastic': [100], 'band': [101], 'simulations': [102], 'unveiled': [103], 'dynamic': [106], 'processes': [107], 'corresponding': [113], 'uridine': [120], 'monophosphate': [121], 'kinase,': [122], 'suggested': [124], 'preferentially': [129], 'binds': [130], 'proteins.': [137], 'When': [138], 'occupy': [142], 'sites,': [146], 'trigger': [149], 'from': [150, 164, 174], 'fuel': [153], 'communication': [155], 'between': [156], 'functional': [159], 'stemmed': [162], 'mainly': [163], 'triphosphate': [166], 'part': [167, 177], 'ATP,': [169], 'with': [170], 'small': [172], 'number': [173], 'adenine': [176], 'Taken': [180], 'together,': [181], 'our': [182], 'results': [183], 'provide': [184], 'overall': [185], 'understanding': [186], 'functions': [190], 'regulation': [193], 'systems.': [196]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2088091011', 'counts_by_year': [{'year': 2024, 'cited_by_count': 4}, {'year': 2023, 'cited_by_count': 8}, {'year': 2022, 'cited_by_count': 12}, {'year': 2021, 'cited_by_count': 5}, {'year': 2020, 'cited_by_count': 8}, {'year': 2019, 'cited_by_count': 4}, {'year': 2018, 'cited_by_count': 6}, {'year': 2017, 'cited_by_count': 9}, {'year': 2016, 'cited_by_count': 14}, {'year': 2015, 'cited_by_count': 10}], 'updated_date': '2024-09-11T14:46:04.706745', 'created_date': '2016-06-24'}