Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2087293823', 'doi': 'https://doi.org/10.1002/ajh.20738', 'title': "Methemoglobin—It's not just blue: A concise review", 'display_name': "Methemoglobin—It's not just blue: A concise review", 'publication_year': 2006, 'publication_date': '2006-09-19', 'ids': {'openalex': 'https://openalex.org/W2087293823', 'doi': 'https://doi.org/10.1002/ajh.20738', 'mag': '2087293823', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/16986127'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ajh.20738', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S199810014', 'display_name': 'American Journal of Hematology', 'issn_l': '0361-8609', 'issn': ['0361-8609', '1096-8652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5073142609', 'display_name': 'Jay N. Umbreit', 'orcid': None}, 'institutions': [], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Jay Umbreit', 'raw_affiliation_strings': ['PPD Inc., Wilmington, North Carolina'], 'affiliations': [{'raw_affiliation_string': 'PPD Inc., Wilmington, North Carolina', 'institution_ids': []}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5073142609'], 'corresponding_institution_ids': [], 'apc_list': {'value': 4940, 'currency': 'USD', 'value_usd': 4940, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.249, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 349, 'citation_normalized_percentile': {'value': 0.999677, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '82', 'issue': '2', 'first_page': '134', 'last_page': '144'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11848', 'display_name': 'Heme Oxygenase-1 and Carbon Monoxide', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11848', 'display_name': 'Heme Oxygenase-1 and Carbon Monoxide', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12845', 'display_name': 'Methemoglobinemia and Tumor Lysis Syndrome', 'score': 0.9997, 'subfield': {'id': 'https://openalex.org/subfields/2740', 'display_name': 'Pulmonary and Respiratory Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12094', 'display_name': 'Hemoglobin structure and function', 'score': 0.9995, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/methemoglobin', 'display_name': 'Methemoglobin', 'score': 0.7146944}], 'concepts': [{'id': 'https://openalex.org/C26865036', 'wikidata': 'https://www.wikidata.org/wiki/Q416833', 'display_name': 'Methemoglobin', 'level': 3, 'score': 0.7146944}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.4720978}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.18451938}, {'id': 'https://openalex.org/C2778917026', 'wikidata': 'https://www.wikidata.org/wiki/Q43041', 'display_name': 'Hemoglobin', 'level': 2, 'score': 0.15182763}], 'mesh': [{'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D008706', 'descriptor_name': 'Methemoglobin', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D050197', 'descriptor_name': 'Atherosclerosis', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D050197', 'descriptor_name': 'Atherosclerosis', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D007249', 'descriptor_name': 'Inflammation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D007501', 'descriptor_name': 'Iron', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008077', 'descriptor_name': 'Lipoproteins, LDL', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008077', 'descriptor_name': 'Lipoproteins, LDL', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008077', 'descriptor_name': 'Lipoproteins, LDL', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008706', 'descriptor_name': 'Methemoglobin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008706', 'descriptor_name': 'Methemoglobin', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D008708', 'descriptor_name': 'Methemoglobinemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008708', 'descriptor_name': 'Methemoglobinemia', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D009569', 'descriptor_name': 'Nitric Oxide', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}, {'descriptor_ui': 'D010084', 'descriptor_name': 'Oxidation-Reduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010100', 'descriptor_name': 'Oxygen', 'qualifier_ui': 'Q000737', 'qualifier_name': 'chemistry', 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1002/ajh.20738', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S199810014', 'display_name': 'American Journal of Hematology', 'issn_l': '0361-8609', 'issn': ['0361-8609', '1096-8652'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/16986127', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.68, 'id': 'https://metadata.un.org/sdg/6', 'display_name': 'Clean water and sanitation'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 103, 'referenced_works': ['https://openalex.org/W1212631268', 'https://openalex.org/W1504205760', 'https://openalex.org/W1509804778', 'https://openalex.org/W1554849134', 'https://openalex.org/W1584104642', 'https://openalex.org/W1599210033', 'https://openalex.org/W1637777503', 'https://openalex.org/W1829187584', 'https://openalex.org/W1918557825', 'https://openalex.org/W1972147667', 'https://openalex.org/W1975465296', 'https://openalex.org/W1981440600', 'https://openalex.org/W1983588728', 'https://openalex.org/W1986567601', 'https://openalex.org/W1988892257', 'https://openalex.org/W1991042120', 'https://openalex.org/W1991923345', 'https://openalex.org/W1992718978', 'https://openalex.org/W1992895531', 'https://openalex.org/W1993044223', 'https://openalex.org/W1993924886', 'https://openalex.org/W2000386923', 'https://openalex.org/W2001078662', 'https://openalex.org/W2003769815', 'https://openalex.org/W2004209427', 'https://openalex.org/W2007737411', 'https://openalex.org/W2011368060', 'https://openalex.org/W2013895772', 'https://openalex.org/W2015877660', 'https://openalex.org/W2019496964', 'https://openalex.org/W2022196444', 'https://openalex.org/W2023691423', 'https://openalex.org/W2026591369', 'https://openalex.org/W2029010155', 'https://openalex.org/W2032041764', 'https://openalex.org/W2033357754', 'https://openalex.org/W2034445068', 'https://openalex.org/W2035959796', 'https://openalex.org/W2038086455', 'https://openalex.org/W2038556736', 'https://openalex.org/W2040884711', 'https://openalex.org/W2046690044', 'https://openalex.org/W2050204181', 'https://openalex.org/W2051105907', 'https://openalex.org/W2052549355', 'https://openalex.org/W2053188361', 'https://openalex.org/W2055810949', 'https://openalex.org/W2060517884', 'https://openalex.org/W2062013217', 'https://openalex.org/W2063405147', 'https://openalex.org/W2066652849', 'https://openalex.org/W2067714284', 'https://openalex.org/W2067739721', 'https://openalex.org/W2068964019', 'https://openalex.org/W2071553717', 'https://openalex.org/W2072877187', 'https://openalex.org/W2075886556', 'https://openalex.org/W2077153802', 'https://openalex.org/W2079556457', 'https://openalex.org/W2079998343', 'https://openalex.org/W2083891009', 'https://openalex.org/W2085692908', 'https://openalex.org/W2086632130', 'https://openalex.org/W2087450601', 'https://openalex.org/W2092175186', 'https://openalex.org/W2093050373', 'https://openalex.org/W2094746732', 'https://openalex.org/W2098767073', 'https://openalex.org/W2119811274', 'https://openalex.org/W2120182098', 'https://openalex.org/W2120306909', 'https://openalex.org/W2120505405', 'https://openalex.org/W2120714892', 'https://openalex.org/W2127322546', 'https://openalex.org/W2127520085', 'https://openalex.org/W2138740507', 'https://openalex.org/W2161262137', 'https://openalex.org/W2162224837', 'https://openalex.org/W2163889067', 'https://openalex.org/W2166747981', 'https://openalex.org/W2167437946', 'https://openalex.org/W2167748258', 'https://openalex.org/W2168545708', 'https://openalex.org/W2169004154', 'https://openalex.org/W2169450299', 'https://openalex.org/W2169952241', 'https://openalex.org/W2171216272', 'https://openalex.org/W2210648408', 'https://openalex.org/W2212683508', 'https://openalex.org/W2265604032', 'https://openalex.org/W2273892554', 'https://openalex.org/W2303733864', 'https://openalex.org/W2321620362', 'https://openalex.org/W2411184005', 'https://openalex.org/W2426283375', 'https://openalex.org/W2444154478', 'https://openalex.org/W269552068', 'https://openalex.org/W4231581922', 'https://openalex.org/W4233690070', 'https://openalex.org/W4234116362', 'https://openalex.org/W4242743693', 'https://openalex.org/W73673827', 'https://openalex.org/W96484744'], 'related_works': ['https://openalex.org/W978626386', 'https://openalex.org/W4389568370', 'https://openalex.org/W3108674512', 'https://openalex.org/W3032375762', 'https://openalex.org/W3031052312', 'https://openalex.org/W2748952813', 'https://openalex.org/W2586801360', 'https://openalex.org/W2080531066', 'https://openalex.org/W1995515455', 'https://openalex.org/W1506200166'], 'abstract_inverted_index': {'Abstract': [0], 'Hemoglobin': [1, 22], 'has': [2, 23, 32], 'functions': [3, 55, 128], 'besides': [4], 'carrying': [5], 'oxygen': [6, 68], 'to': [7, 77, 83], 'the': [8, 26, 35, 53, 67, 71, 91, 114, 135], 'tissues,': [9], 'and': [10, 14, 30, 73], 'regulates': [11], 'vascular': [12, 85], 'tone': [13], 'inflammation': [15], 'via': [16], 'a': [17, 41, 57], 'redox': [18], 'couple': [19, 54], 'with': [20, 40], 'methemoglobin.': [21], 'iron': [24, 33], 'in': [25, 34, 70, 124, 134, 141], 'reduced': [27], 'valance': [28, 37], 'Fe(II)': [29], 'methemoglobin': [31, 52, 103, 119], 'oxidized': [36], 'Fe': [38], '(III),': [39], 'free': [42], 'energy': [43], 'capable': [44], 'of': [45, 62, 64, 93, 106, 116, 137], 'producing': [46], 'water': [47], 'from': [48, 81, 118], 'oxygen.': [49], 'In': [50, 112], 'generating': [51], 'as': [56], 'nitrite': [58, 82], 'reductase.': [59], 'The': [60], 'degree': [61], 'oxidation': [63, 105, 136], 'hemoglobin': [65, 95], 'senses': [66], 'level': [69], 'blood': [72, 88], 'uses': [74], 'its': [75], 'ability': [76], 'produce': [78], 'nitric': [79], 'oxide': [80], 'control': [84], 'tone,': [86], 'increasing': [87], 'flood': [89], 'when': [90], 'proportion': [92], 'oxygenated': [94], 'falls.': [96], 'Additional': [97], 'cardiovascular': [98], 'damage': [99], 'is': [100, 120], 'produced': [101], 'by': [102, 131], 'mediated': [104], 'light': [107], 'density': [108], 'lipoproteins,': [109], 'accelerating': [110], 'arteriosclerosis.': [111], 'addition,': [113], 'release': [115], 'heme': [117], 'an': [121], 'important': [122], 'factor': [123], 'inflammation.': [125], 'These': [126], 'physiologic': [127], 'are': [129], 'paralleled': [130], 'thewell‐described': [132], 'role': [133], 'various': [138], 'drugs': [139], 'resulting': [140], 'methemoglobinemia.': [142], 'Am.': [143], 'J.': [144], 'Hematol.,': [145], '2006.': [146], '©': [147], '2006': [148], 'Wiley‐Liss,': [149], 'Inc.': [150]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2087293823', 'counts_by_year': [{'year': 2024, 'cited_by_count': 13}, {'year': 2023, 'cited_by_count': 32}, {'year': 2022, 'cited_by_count': 21}, {'year': 2021, 'cited_by_count': 22}, {'year': 2020, 'cited_by_count': 24}, {'year': 2019, 'cited_by_count': 29}, {'year': 2018, 'cited_by_count': 21}, {'year': 2017, 'cited_by_count': 18}, {'year': 2016, 'cited_by_count': 24}, {'year': 2015, 'cited_by_count': 17}, {'year': 2014, 'cited_by_count': 12}, {'year': 2013, 'cited_by_count': 20}, {'year': 2012, 'cited_by_count': 17}], 'updated_date': '2024-12-29T23:10:34.558349', 'created_date': '2016-06-24'}