Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2087263087', 'doi': 'https://doi.org/10.1111/j.1749-6632.1977.tb41847.x', 'title': 'A β‐LPH PRECURSOR MODEL: RECENT DEVELOPMENTS CONCERNING MORPHINE‐LIKE SUBSTANCES', 'display_name': 'A β‐LPH PRECURSOR MODEL: RECENT DEVELOPMENTS CONCERNING MORPHINE‐LIKE SUBSTANCES', 'publication_year': 1977, 'publication_date': '1977-10-01', 'ids': {'openalex': 'https://openalex.org/W2087263087', 'doi': 'https://doi.org/10.1111/j.1749-6632.1977.tb41847.x', 'mag': '2087263087', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/279264'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1749-6632.1977.tb41847.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8802318', 'display_name': 'Annals of the New York Academy of Sciences', 'issn_l': '0077-8923', 'issn': ['0077-8923', '1749-6632'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5009035456', 'display_name': 'Michel Chrètien', 'orcid': 'https://orcid.org/0000-0002-8588-4460'}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'M. Chrétien', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5090995081', 'display_name': 'Nabil G. Seidah', 'orcid': 'https://orcid.org/0000-0001-6503-9342'}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'N. G. Seidah', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5065470757', 'display_name': 'Suzanne Benjannet', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'S. Benjannet', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5040625848', 'display_name': 'N. Dragon', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'N. Dragon', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5111557717', 'display_name': 'R. Routhier', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'R. Routhier', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5053825481', 'display_name': 'T Motomatsu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'T. Motomatsu', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5074964938', 'display_name': 'Philippe Crine', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'P. Crine', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111617571', 'display_name': 'M. Lis', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I4210158752', 'display_name': 'Montreal Clinical Research Institute', 'ror': 'https://ror.org/05m8pzq90', 'country_code': 'CA', 'type': 'facility', 'lineage': ['https://openalex.org/I4210158752', 'https://openalex.org/I70931966']}], 'countries': ['CA'], 'is_corresponding': False, 'raw_author_name': 'M. Lis', 'raw_affiliation_strings': ['Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada'], 'affiliations': [{'raw_affiliation_string': 'Protein and Pituitary Hormone Laboratory Clinical Research Institute of Montreal Montreal, Quebec, Canada', 'institution_ids': ['https://openalex.org/I4210158752']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4840, 'currency': 'USD', 'value_usd': 4840, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.845, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 28, 'citation_normalized_percentile': {'value': 0.558835, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 90, 'max': 91}, 'biblio': {'volume': '297', 'issue': '1', 'first_page': '84', 'last_page': '105'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11178', 'display_name': 'Receptor Mechanisms and Signaling', 'score': 0.9972, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10814', 'display_name': 'Neuropeptides and Animal Physiology', 'score': 0.9963, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10748', 'display_name': 'Growth Hormone and Insulin-like Growth Factors', 'score': 0.9943, 'subfield': {'id': 'https://openalex.org/subfields/2712', 'display_name': 'Endocrinology, Diabetes and Metabolism'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/endorphins', 'display_name': 'Endorphins', 'score': 0.9045525}, {'id': 'https://openalex.org/keywords/beta-endorphin', 'display_name': 'beta-Endorphin', 'score': 0.6978728}, {'id': 'https://openalex.org/keywords/opiate', 'display_name': 'Opiate', 'score': 0.54712266}, {'id': 'https://openalex.org/keywords/beta', 'display_name': 'BETA (programming language)', 'score': 0.45560542}], 'concepts': [{'id': 'https://openalex.org/C2778680817', 'wikidata': 'https://www.wikidata.org/wiki/Q190528', 'display_name': 'Endorphins', 'level': 2, 'score': 0.9045525}, {'id': 'https://openalex.org/C2777658017', 'wikidata': 'https://www.wikidata.org/wiki/Q156871', 'display_name': 'Pituitary gland', 'level': 3, 'score': 0.7311231}, {'id': 'https://openalex.org/C2777557602', 'wikidata': 'https://www.wikidata.org/wiki/Q2993328', 'display_name': 'beta-Endorphin', 'level': 2, 'score': 0.6978728}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.57552606}, {'id': 'https://openalex.org/C2778140631', 'wikidata': 'https://www.wikidata.org/wiki/Q2026938', 'display_name': 'Opiate', 'level': 3, 'score': 0.54712266}, {'id': 'https://openalex.org/C2779029589', 'wikidata': 'https://www.wikidata.org/wiki/Q356002', 'display_name': 'Anterior pituitary', 'level': 3, 'score': 0.5207529}, {'id': 'https://openalex.org/C134018914', 'wikidata': 'https://www.wikidata.org/wiki/Q162606', 'display_name': 'Endocrinology', 'level': 1, 'score': 0.49240148}, {'id': 'https://openalex.org/C16613235', 'wikidata': 'https://www.wikidata.org/wiki/Q285982', 'display_name': 'Endogeny', 'level': 2, 'score': 0.47218052}, {'id': 'https://openalex.org/C2776174256', 'wikidata': 'https://www.wikidata.org/wiki/Q830842', 'display_name': 'BETA (programming language)', 'level': 2, 'score': 0.45560542}, {'id': 'https://openalex.org/C2777389121', 'wikidata': 'https://www.wikidata.org/wiki/Q81225', 'display_name': 'Morphine', 'level': 2, 'score': 0.451212}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.45074517}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.30556458}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.25507647}, {'id': 'https://openalex.org/C71315377', 'wikidata': 'https://www.wikidata.org/wiki/Q11364', 'display_name': 'Hormone', 'level': 2, 'score': 0.22621307}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.19425929}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.17030051}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.0}, {'id': 'https://openalex.org/C199360897', 'wikidata': 'https://www.wikidata.org/wiki/Q9143', 'display_name': 'Programming language', 'level': 1, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D004723', 'descriptor_name': 'Endorphins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D008083', 'descriptor_name': 'beta-Lipotropin', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': True}, {'descriptor_ui': 'D000595', 'descriptor_name': 'Amino Acid Sequence', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002417', 'descriptor_name': 'Cattle', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004723', 'descriptor_name': 'Endorphins', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D004723', 'descriptor_name': 'Endorphins', 'qualifier_ui': 'Q000302', 'qualifier_name': 'isolation & purification', 'is_major_topic': False}, {'descriptor_ui': 'D004723', 'descriptor_name': 'Endorphins', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009074', 'descriptor_name': 'Melanocyte-Stimulating Hormones', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009074', 'descriptor_name': 'Melanocyte-Stimulating Hormones', 'qualifier_ui': 'Q000096', 'qualifier_name': 'biosynthesis', 'is_major_topic': False}, {'descriptor_ui': 'D010902', 'descriptor_name': 'Pituitary Gland', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010902', 'descriptor_name': 'Pituitary Gland', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D012756', 'descriptor_name': 'Sheep', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013552', 'descriptor_name': 'Swine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008083', 'descriptor_name': 'beta-Lipotropin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1111/j.1749-6632.1977.tb41847.x', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S8802318', 'display_name': 'Annals of the New York Academy of Sciences', 'issn_l': '0077-8923', 'issn': ['0077-8923', '1749-6632'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320595', 'host_organization_name': 'Wiley', 'host_organization_lineage': ['https://openalex.org/P4310320595'], 'host_organization_lineage_names': ['Wiley'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/279264', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 52, 'referenced_works': ['https://openalex.org/W151261625', 'https://openalex.org/W1544308534', 'https://openalex.org/W1545566831', 'https://openalex.org/W1551834526', 'https://openalex.org/W1589632926', 'https://openalex.org/W1964338246', 'https://openalex.org/W1967511463', 'https://openalex.org/W1971230167', 'https://openalex.org/W1973518182', 'https://openalex.org/W1976459980', 'https://openalex.org/W1979385488', 'https://openalex.org/W1988751611', 'https://openalex.org/W1993508650', 'https://openalex.org/W1993749950', 'https://openalex.org/W2000184187', 'https://openalex.org/W2010051841', 'https://openalex.org/W2014269448', 'https://openalex.org/W2019624726', 'https://openalex.org/W2022756314', 'https://openalex.org/W2023126539', 'https://openalex.org/W2023290209', 'https://openalex.org/W2023901224', 'https://openalex.org/W2026575756', 'https://openalex.org/W2029096988', 'https://openalex.org/W2030288420', 'https://openalex.org/W2031168085', 'https://openalex.org/W2032555851', 'https://openalex.org/W2038936439', 'https://openalex.org/W2039573260', 'https://openalex.org/W2039841065', 'https://openalex.org/W2055108248', 'https://openalex.org/W2060697111', 'https://openalex.org/W2061639303', 'https://openalex.org/W2066365921', 'https://openalex.org/W2069008904', 'https://openalex.org/W2070661519', 'https://openalex.org/W2075044590', 'https://openalex.org/W2077017070', 'https://openalex.org/W2084093985', 'https://openalex.org/W2084484167', 'https://openalex.org/W2086779375', 'https://openalex.org/W2089462923', 'https://openalex.org/W2090278310', 'https://openalex.org/W2090699964', 'https://openalex.org/W2093477186', 'https://openalex.org/W2143206877', 'https://openalex.org/W2167089066', 'https://openalex.org/W2328038097', 'https://openalex.org/W2401688274', 'https://openalex.org/W2410782118', 'https://openalex.org/W2412997314', 'https://openalex.org/W2444197391'], 'related_works': ['https://openalex.org/W3037926329', 'https://openalex.org/W2407662096', 'https://openalex.org/W2404703847', 'https://openalex.org/W2133591619', 'https://openalex.org/W2091241147', 'https://openalex.org/W2087626331', 'https://openalex.org/W2035878622', 'https://openalex.org/W2032307762', 'https://openalex.org/W1964192797', 'https://openalex.org/W143786280'], 'abstract_inverted_index': {'In': [0], 'summary,': [1], 'the': [2, 35, 67, 75, 80, 95, 108, 114, 129, 153, 192, 196, 200, 217, 231, 255, 314, 326, 342], 'pituitary': [3, 76, 193], 'glands': [4, 106], 'from': [5, 235], 'at': [6], 'least': [7], 'four': [8], 'species': [9], 'contain': [10], 'betaLPH': [11, 25, 86, 178, 206, 317], 'and': [12, 13, 29, 52, 59, 87, 107, 179, 204, 224, 257, 318], 'beta': [14], 'endorphins.': [15], 'We': [16, 98, 213], 'have': [17, 99, 171, 214, 322], 'shown': [18], 'that': [19, 82, 144, 177, 191, 205, 239], 'in': [20, 94, 104, 132, 159, 184, 261, 269, 279, 281, 328, 341], 'slices': [21], 'of': [22, 57, 61, 69, 74, 85, 117, 169, 199, 230, 308, 316, 331, 344], 'whole': [23], 'pituitaries': [24], 'is': [26, 40, 110, 135, 157, 195, 207, 250], 'actively': [27, 182], 'biosynthesized': [28, 47, 183], 'transformed': [30], 'into': [31, 142, 152], 'gammaLPH,': [32], 'thus': [33], 'releasing': [34], 'COOH-terminus': [36], 'portion': [37], '61--91,': [38], 'which': [39, 170, 267], 'now': [41], 'known': [42], 'as': [43, 162], 'beta-endorphin.': [44], 'Newly': [45], 'radioactive': [46], 'beta-endorphin': [48, 62, 151, 180], 'has': [49], 'been': [50], 'clearly': [51], 'definitely': [53], 'identified.': [54], 'The': [55, 71, 305], 'release': [56], 'betaMSH': [58], 'possibly': [60], 'could': [63, 149], 'well': [64], 'be': [65, 79], 'under': [66], 'control': [68], 'CRF.': [70], 'intermediate': [72], 'lobe': [73], 'seems': [77], 'to': [78, 113, 127, 140, 253, 325], 'tissue': [81], 'contains': [83], 'most': [84, 310], 'beta-endorphin,': [88], 'although': [89], 'these': [90, 122], 'are': [91, 181, 226, 241, 259], 'also': [92], 'present': [93], 'anterior': [96], 'lobe.': [97], 'recently': [100], 'demonstrated': [101], 'its': [102, 208, 245, 319], 'presence': [103], 'human': [105, 118], 'structure': [109], 'completely': [111], 'identical': [112], 'COOH-fragment': [115], '61--91': [116], 'betaLPH.': [119], 'Thus': [120, 247], 'far,': [121, 248], 'morphine-like': [123, 334], 'peptides': [124, 321], 'seem': [125], 'not': [126], 'cross': [128], 'blood-brain': [130], 'barrier': [131], 'rats;': [133], 'it': [134, 156], 'conceivable': [136], '(neurophysiologists': [137], 'will': [138], 'need': [139], 'look': [141], 'it)': [143], 'an': [145, 332], 'upward': [146], 'circulatory': [147], 'process': [148], 'bring': [150], 'brain': [154], 'where': [155], 'concentrated': [158], 'different': [160], 'regions': [161], 'either': [163], 'native': [164], 'or': [165, 209], 'degraded': [166], 'products': [167], 'both': [168], 'similar': [172], 'activities.': [173], 'Until': [174], 'somebody': [175], 'shows': [176], 'other': [185], 'tissues,': [186], 'one': [187, 234], 'can': [188], 'only': [189], 'assume': [190], 'gland': [194], 'primary': [197], 'source': [198], 'endogenous': [201, 333], 'opiate': [202], 'substance(s)': [203], 'their': [210], 'biologic': [211], 'precursor.': [212], 'worked': [215], 'on': [216, 313], 'proposed': [218], 'biosynthetic': [219], 'model': [220], 'for': [221], 'many': [222], 'years': [223], 'we': [225, 240, 258], 'continuing': [227], 'because': [228], 'all': [229], 'experiments,': [232], 'except': [233], 'another': [236], 'laboratory,': [237], '38indicate': [238], 'moving': [242], 'slowly': [243], 'toward': [244], 'confirmation.': [246], 'there': [249], 'no': [251], 'reason': [252], 'believe': [254], 'contrary,': [256], 'following': [260], 'some': [262], 'ways': [263], 'Konrad': [264], "Lorenz's": [265], 'maxim,': [266], 'appeared': [268], 'his': [270], 'book': [271], 'Die': [272], 'Acht': [273], 'Todsunden': [274], 'Der': [275], 'Zivilisierten': [276], 'Menscheit,': [277], 'published': [278], 'French': [280], '1973:': [282], '"Une': [283], 'bonne': [284], 'hypothése': [285], 'de': [286, 294, 297], 'travail': [287], 'gagne': [288], 'en': [289], 'vraisemblance': [290], 'lorsque,': [291], 'au': [292], 'cours': [293], 'longues': [295], 'années': [296], 'recherches,': [298], 'nulle': [299], 'donnée': [300], "n'est": [301], 'venue': [302], 'la': [303], 'contredire."': [304], 'major': [306, 339], 'conclusion': [307], 'our': [309], 'recent': [311], 'studies': [312], 'biosynthesis': [315, 330], 'related': [320], 'led': [323], 'us': [324], 'first': [327], 'vitro': [329], 'substance.': [335], 'This': [336], 'constitutes': [337], 'a': [338], 'step': [340], 'comprehension': [343], 'this': [345], 'exciting': [346], 'new': [347], 'field.': [348]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2087263087', 'counts_by_year': [], 'updated_date': '2024-12-08T17:30:18.170779', 'created_date': '2016-06-24'}