Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2087214667', 'doi': 'https://doi.org/10.1371/journal.pone.0071334', 'title': 'Expansion of Multipotent Stem Cells from the Adult Human Brain', 'display_name': 'Expansion of Multipotent Stem Cells from the Adult Human Brain', 'publication_year': 2013, 'publication_date': '2013-08-14', 'ids': {'openalex': 'https://openalex.org/W2087214667', 'doi': 'https://doi.org/10.1371/journal.pone.0071334', 'mag': '2087214667', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/23967194', 'pmcid': 'https://www.ncbi.nlm.nih.gov/pmc/articles/3743777'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0071334', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071334&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'gold', 'oa_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071334&type=printable', 'any_repository_has_fulltext': True}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5039225238', 'display_name': 'Wayne Murrell', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Wayne Murrell', 'raw_affiliation_strings': ['Norwegian Center for Stem Cell Research, Oslo University Hospital, Oslo, Norway', 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Norwegian Center for Stem Cell Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}, {'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044354610', 'display_name': 'Emily Palmero', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Emily Palmero', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5077542447', 'display_name': 'John Bianco', 'orcid': 'https://orcid.org/0000-0001-5717-5125'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'John Bianco', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5044030005', 'display_name': 'Biljana Stangeland', 'orcid': 'https://orcid.org/0000-0002-1723-9742'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Biljana Stangeland', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091101546', 'display_name': 'Mrinal Joel', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Mrinal Joel', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021402706', 'display_name': 'Linda Paulson', 'orcid': 'https://orcid.org/0000-0002-8109-0700'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Linda Paulson', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5012839579', 'display_name': 'Bernd Thiede', 'orcid': 'https://orcid.org/0000-0002-2804-9522'}, 'institutions': [{'id': 'https://openalex.org/I184942183', 'display_name': 'University of Oslo', 'ror': 'https://ror.org/01xtthb56', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I184942183']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Bernd Thiede', 'raw_affiliation_strings': ['The Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'The Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway', 'institution_ids': ['https://openalex.org/I184942183']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5081549003', 'display_name': 'Zanina Grieg', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Zanina Grieg', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5091583293', 'display_name': 'Ingunn Ramsnes', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Ingunn Ramsnes', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5054415263', 'display_name': 'Håvard Kjesbu Skjellegrind', 'orcid': 'https://orcid.org/0000-0003-3067-0016'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Håvard K. Skjellegrind', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5033349701', 'display_name': 'Ståle Nygård', 'orcid': 'https://orcid.org/0000-0002-5263-4748'}, 'institutions': [{'id': 'https://openalex.org/I184942183', 'display_name': 'University of Oslo', 'ror': 'https://ror.org/01xtthb56', 'country_code': 'NO', 'type': 'education', 'lineage': ['https://openalex.org/I184942183']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Ståle Nygård', 'raw_affiliation_strings': ['Research Group for Biomedical Informatics, University of Oslo, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Research Group for Biomedical Informatics, University of Oslo, Oslo, Norway', 'institution_ids': ['https://openalex.org/I184942183']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5029756439', 'display_name': 'Petter Brandal', 'orcid': 'https://orcid.org/0000-0003-0259-495X'}, 'institutions': [{'id': 'https://openalex.org/I2801049993', 'display_name': 'Norwegian Cancer Society', 'ror': 'https://ror.org/01925vb10', 'country_code': 'NO', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I2801049993']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Petter Brandal', 'raw_affiliation_strings': ['Center for Cancer Biomedicine, The Norwegian Radium Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Center for Cancer Biomedicine, The Norwegian Radium Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I2801049993']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5045465211', 'display_name': 'Cecilie Sandberg', 'orcid': 'https://orcid.org/0000-0002-9682-1019'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Cecilie Sandberg', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5021592085', 'display_name': 'Einar Osland Vik-Mo', 'orcid': 'https://orcid.org/0000-0001-8303-4123'}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Einar Vik-Mo', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5007651319', 'display_name': 'Sheryl Palmero', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Sheryl Palmero', 'raw_affiliation_strings': ['Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5111410534', 'display_name': 'Iver A. Langmoen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I1281400175', 'display_name': 'Oslo University Hospital', 'ror': 'https://ror.org/00j9c2840', 'country_code': 'NO', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1281400175']}], 'countries': ['NO'], 'is_corresponding': True, 'raw_author_name': 'Iver A. Langmoen', 'raw_affiliation_strings': ['Department of Neurosurgery, Oslo University Hospital, Oslo, Norway', 'Norwegian Center for Stem Cell Research, Oslo University Hospital, Oslo, Norway', 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway'], 'affiliations': [{'raw_affiliation_string': 'Department of Neurosurgery, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}, {'raw_affiliation_string': 'Vilhelm Magnus Laboratory for Neurosurgical Research, Institute for Surgical Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}, {'raw_affiliation_string': 'Norwegian Center for Stem Cell Research, Oslo University Hospital, Oslo, Norway', 'institution_ids': ['https://openalex.org/I1281400175']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 3, 'corresponding_author_ids': ['https://openalex.org/A5039225238', 'https://openalex.org/A5044354610', 'https://openalex.org/A5077542447', 'https://openalex.org/A5044030005', 'https://openalex.org/A5091101546', 'https://openalex.org/A5021402706', 'https://openalex.org/A5012839579', 'https://openalex.org/A5081549003', 'https://openalex.org/A5091583293', 'https://openalex.org/A5054415263', 'https://openalex.org/A5033349701', 'https://openalex.org/A5029756439', 'https://openalex.org/A5045465211', 'https://openalex.org/A5021592085', 'https://openalex.org/A5007651319', 'https://openalex.org/A5111410534'], 'corresponding_institution_ids': ['https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I184942183', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I184942183', 'https://openalex.org/I2801049993', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175', 'https://openalex.org/I1281400175'], 'apc_list': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'apc_paid': {'value': 1805, 'currency': 'USD', 'value_usd': 1805, 'provenance': 'doaj'}, 'fwci': 2.321, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 42, 'citation_normalized_percentile': {'value': 0.884369, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 94, 'max': 95}, 'biblio': {'volume': '8', 'issue': '8', 'first_page': 'e71334', 'last_page': 'e71334'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10505', 'display_name': 'Pluripotent Stem Cells Research', 'score': 0.9988, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12264', 'display_name': 'Tissue Engineering and Regenerative Medicine', 'score': 0.9962, 'subfield': {'id': 'https://openalex.org/subfields/2746', 'display_name': 'Surgery'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10176', 'display_name': 'Mesenchymal stem cell research', 'score': 0.9941, 'subfield': {'id': 'https://openalex.org/subfields/2716', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/multipotent-stem-cell', 'display_name': 'Multipotent Stem Cell', 'score': 0.6003922}, {'id': 'https://openalex.org/keywords/human-brain', 'display_name': 'Human brain', 'score': 0.5476491}], 'concepts': [{'id': 'https://openalex.org/C28328180', 'wikidata': 'https://www.wikidata.org/wiki/Q48196', 'display_name': 'Stem cell', 'level': 2, 'score': 0.79593384}, {'id': 'https://openalex.org/C2777933648', 'wikidata': 'https://www.wikidata.org/wiki/Q21114866', 'display_name': 'SOX2', 'level': 4, 'score': 0.79502225}, {'id': 'https://openalex.org/C20875687', 'wikidata': 'https://www.wikidata.org/wiki/Q2642600', 'display_name': 'Adult stem cell', 'level': 4, 'score': 0.68464464}, {'id': 'https://openalex.org/C136834591', 'wikidata': 'https://www.wikidata.org/wiki/Q2944097', 'display_name': 'Neural stem cell', 'level': 3, 'score': 0.65423167}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.60889095}, {'id': 'https://openalex.org/C2910776680', 'wikidata': 'https://www.wikidata.org/wiki/Q862600', 'display_name': 'Multipotent Stem Cell', 'level': 4, 'score': 0.6003922}, {'id': 'https://openalex.org/C143441281', 'wikidata': 'https://www.wikidata.org/wiki/Q5133858', 'display_name': 'Clinical uses of mesenchymal stem cells', 'level': 5, 'score': 0.5781223}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5521228}, {'id': 'https://openalex.org/C2777670902', 'wikidata': 'https://www.wikidata.org/wiki/Q492038', 'display_name': 'Human brain', 'level': 2, 'score': 0.5476491}, {'id': 'https://openalex.org/C13685319', 'wikidata': 'https://www.wikidata.org/wiki/Q7607302', 'display_name': 'Stem cell transplantation for articular cartilage repair', 'level': 5, 'score': 0.45007777}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.44597602}, {'id': 'https://openalex.org/C2911091166', 'wikidata': 'https://www.wikidata.org/wiki/Q106419912', 'display_name': 'Transplantation', 'level': 2, 'score': 0.43723416}, {'id': 'https://openalex.org/C148738053', 'wikidata': 'https://www.wikidata.org/wiki/Q210861', 'display_name': 'Cellular differentiation', 'level': 3, 'score': 0.4259186}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.25102413}, {'id': 'https://openalex.org/C201750760', 'wikidata': 'https://www.wikidata.org/wiki/Q1896218', 'display_name': 'Progenitor cell', 'level': 3, 'score': 0.22858119}, {'id': 'https://openalex.org/C145103041', 'wikidata': 'https://www.wikidata.org/wiki/Q1151519', 'display_name': 'Embryonic stem cell', 'level': 3, 'score': 0.21117684}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.12369263}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.1102556}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.09555298}], 'mesh': [{'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D018929', 'descriptor_name': 'Cell Culture Techniques', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D039902', 'descriptor_name': 'Multipotent Stem Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': True}, {'descriptor_ui': 'D000328', 'descriptor_name': 'Adult', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001921', 'descriptor_name': 'Brain', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018929', 'descriptor_name': 'Cell Culture Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002454', 'descriptor_name': 'Cell Differentiation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002999', 'descriptor_name': 'Clone Cells', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D002999', 'descriptor_name': 'Clone Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D059290', 'descriptor_name': 'Dopaminergic Neurons', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D059290', 'descriptor_name': 'Dopaminergic Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005786', 'descriptor_name': 'Gene Expression Regulation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007621', 'descriptor_name': 'Karyotyping', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008875', 'descriptor_name': 'Middle Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039902', 'descriptor_name': 'Multipotent Stem Cells', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D039902', 'descriptor_name': 'Multipotent Stem Cells', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010641', 'descriptor_name': 'Phenotype', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D040901', 'descriptor_name': 'Proteomics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013194', 'descriptor_name': 'Staining and Labeling', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 5, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0071334', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071334&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://europepmc.org/articles/pmc3743777', 'pdf_url': 'https://europepmc.org/articles/pmc3743777?pdf=render', 'source': {'id': 'https://openalex.org/S4306400806', 'display_name': 'Europe PMC (PubMed Central)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1303153112', 'host_organization_name': 'European Bioinformatics Institute', 'host_organization_lineage': ['https://openalex.org/I1303153112'], 'host_organization_lineage_names': ['European Bioinformatics Institute'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743777', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S2764455111', 'display_name': 'PubMed Central', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': True, 'landing_page_url': 'https://figshare.com/articles/dataset/_Expansion_of_Multipotent_Stem_Cells_from_the_Adult_Human_Brain_/772509', 'pdf_url': 'https://figshare.com/ndownloader/files/1169731', 'source': {'id': 'https://openalex.org/S4306402621', 'display_name': 'INDIGO (University of Illinois at Chicago)', 'issn_l': None, 'issn': None, 'is_oa': True, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I39422238', 'host_organization_name': 'University of Illinois Chicago', 'host_organization_lineage': ['https://openalex.org/I39422238'], 'host_organization_lineage_names': ['University of Illinois Chicago'], 'type': 'repository'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'submittedVersion', 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/23967194', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1371/journal.pone.0071334', 'pdf_url': 'https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0071334&type=printable', 'source': {'id': 'https://openalex.org/S202381698', 'display_name': 'PLoS ONE', 'issn_l': '1932-6203', 'issn': ['1932-6203'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310315706', 'host_organization_name': 'Public Library of Science', 'host_organization_lineage': ['https://openalex.org/P4310315706'], 'host_organization_lineage_names': ['Public Library of Science'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.72}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 75, 'referenced_works': ['https://openalex.org/W1859089489', 'https://openalex.org/W1966569961', 'https://openalex.org/W1969015262', 'https://openalex.org/W1969071735', 'https://openalex.org/W1977689261', 'https://openalex.org/W1980962977', 'https://openalex.org/W1981371990', 'https://openalex.org/W1989031533', 'https://openalex.org/W1997496613', 'https://openalex.org/W2003890579', 'https://openalex.org/W2004340341', 'https://openalex.org/W2008929541', 'https://openalex.org/W2009660843', 'https://openalex.org/W2019046972', 'https://openalex.org/W2019894272', 'https://openalex.org/W2020541351', 'https://openalex.org/W2021766835', 'https://openalex.org/W2027284410', 'https://openalex.org/W2030508161', 'https://openalex.org/W2032062826', 'https://openalex.org/W2041435551', 'https://openalex.org/W2044379131', 'https://openalex.org/W2044955918', 'https://openalex.org/W2047082977', 'https://openalex.org/W2048731214', 'https://openalex.org/W2051446802', 'https://openalex.org/W2053445847', 'https://openalex.org/W2069477235', 'https://openalex.org/W2070613645', 'https://openalex.org/W2071392158', 'https://openalex.org/W2073659698', 'https://openalex.org/W2077007919', 'https://openalex.org/W2078201066', 'https://openalex.org/W2079356804', 'https://openalex.org/W2080203045', 'https://openalex.org/W2080752012', 'https://openalex.org/W2089598607', 'https://openalex.org/W2094540897', 'https://openalex.org/W2097900772', 'https://openalex.org/W2098015360', 'https://openalex.org/W2104978512', 'https://openalex.org/W2107890140', 'https://openalex.org/W2111651969', 'https://openalex.org/W2113954530', 'https://openalex.org/W2116177074', 'https://openalex.org/W2117008800', 'https://openalex.org/W2118069309', 'https://openalex.org/W2118353064', 'https://openalex.org/W2118929543', 'https://openalex.org/W2120865735', 'https://openalex.org/W2122196385', 'https://openalex.org/W2123094693', 'https://openalex.org/W2128984725', 'https://openalex.org/W2130010891', 'https://openalex.org/W2134749398', 'https://openalex.org/W2138255346', 'https://openalex.org/W2138977668', 'https://openalex.org/W2144268541', 'https://openalex.org/W2150817988', 'https://openalex.org/W2151848959', 'https://openalex.org/W2154449404', 'https://openalex.org/W2158646376', 'https://openalex.org/W2166400478', 'https://openalex.org/W2166909073', 'https://openalex.org/W2168221215', 'https://openalex.org/W2168341415', 'https://openalex.org/W2169392156', 'https://openalex.org/W2170951443', 'https://openalex.org/W2173497140', 'https://openalex.org/W2329486167', 'https://openalex.org/W2339359539', 'https://openalex.org/W2424847179', 'https://openalex.org/W3103154150', 'https://openalex.org/W3216705818', 'https://openalex.org/W4254771834'], 'related_works': ['https://openalex.org/W42115488', 'https://openalex.org/W2802895030', 'https://openalex.org/W2551206724', 'https://openalex.org/W2351914518', 'https://openalex.org/W2350774254', 'https://openalex.org/W2143441328', 'https://openalex.org/W2101334815', 'https://openalex.org/W2085491292', 'https://openalex.org/W1986604564', 'https://openalex.org/W1985229106'], 'abstract_inverted_index': {'The': [0], 'discovery': [1], 'of': [2, 17, 26, 63, 70, 85, 103, 124, 150, 165, 169], 'stem': [3, 34, 88, 106, 128, 174], 'cells': [4, 35, 52, 89, 129, 138], 'in': [5, 139, 141], 'the': [6, 18, 42, 81, 120, 162], 'adult': [7, 32, 125, 171], 'human': [8, 31, 86, 126], 'brain': [9, 87, 92], 'has': [10, 46], 'revealed': [11], 'new': [12], 'possible': [13], 'scenarios': [14], 'for': [15, 80, 161], 'treatment': [16], 'sick': [19], 'or': [20], 'injured': [21], 'brain.': [22], 'Both': [23], 'clinical': [24], 'use': [25], 'and': [27, 59, 83, 112, 145], 'preclinical': [28], 'research': [29], 'on': [30], 'neural': [33], 'have,': [36], 'however,': [37], 'been': [38, 47], 'seriously': [39], 'hampered': [40], 'by': [41, 167], 'fact': [43], 'that': [44], 'it': [45], 'impossible': [48], 'to': [49], 'passage': [50], 'these': [51, 137, 151], 'more': [53], 'than': [54], 'a': [55, 68], 'very': [56], 'few': [57], 'times': [58], 'with': [60], 'little': [61], 'expansion': [62, 102], 'cell': [64, 107], 'numbers.': [65], 'Having': [66], 'explored': [67], 'number': [69], 'alternative': [71], 'culturing': [72], 'conditions': [73], 'we': [74, 95], 'here': [75], 'present': [76], 'an': [77, 104, 170], 'efficient': [78], 'method': [79], 'establishment': [82], 'propagation': [84], 'from': [90], 'whatever': [91], 'tissue': [93, 133], 'samples': [94], 'have': [96], 'tried.': [97], 'We': [98, 135], 'describe': [99], 'virtually': [100], 'unlimited': [101], 'authentic': [105], 'phenotype.': [108], 'Pluripotency': [109], 'proteins': [110], 'Sox2': [111], 'Oct4': [113], 'are': [114], 'expressed': [115], 'without': [116], 'artificial': [117], 'induction.': [118], 'For': [119], 'first': [121], 'time': [122], 'multipotency': [123], 'brain-derived': [127], 'is': [130, 154], 'demonstrated': [131], 'beyond': [132], 'boundaries.': [134], 'characterize': [136], 'detail': [140], 'vitro': [142], 'including': [143], 'microarray': [144], 'proteomic': [146], 'approaches.': [147], 'Whilst': [148], 'clarification': [149], "cells'": [152], 'behavior': [153], 'ongoing,': [155], 'results': [156], 'so': [157], 'far': [158], 'portend': [159], 'well': [160], 'future': [163], 'repair': [164], 'tissues': [166], 'transplantation': [168], "patient's": [172], 'own-derived': [173], 'cells.': [175]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2087214667', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 6}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 5}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 5}, {'year': 2016, 'cited_by_count': 5}, {'year': 2015, 'cited_by_count': 6}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 2}], 'updated_date': '2024-12-10T23:24:17.748603', 'created_date': '2016-06-24'}