Publication Information

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'https://openalex.org/W2140277678', 'https://openalex.org/W2146634463', 'https://openalex.org/W2146796201', 'https://openalex.org/W2147286587', 'https://openalex.org/W2157903759', 'https://openalex.org/W2402106702'], 'related_works': ['https://openalex.org/W3015678326', 'https://openalex.org/W2392029702', 'https://openalex.org/W2092033815', 'https://openalex.org/W2089114560', 'https://openalex.org/W2073321338', 'https://openalex.org/W2060075608', 'https://openalex.org/W2040128205', 'https://openalex.org/W2026444950', 'https://openalex.org/W1438272007', 'https://openalex.org/W131865840'], 'abstract_inverted_index': {'T': [0, 24, 197, 203, 227, 400, 699, 1027, 1073, 1176, 1288, 1305, 1378, 1426, 1474, 1480, 1690, 1752, 1984, 2171, 2194, 2238, 2387, 2421, 2694, 2758, 2800, 2831, 2837, 3068, 3490, 3818, 3864, 3967, 4079, 4096, 4169, 4217, 4265, 4271, 4481, 4543, 4775, 4962, 4985, 5029, 5178], 'cell': [1, 198, 204, 401, 407, 419, 700, 1028, 1036, 1045, 1306, 1379, 1475, 1481, 1691, 1985, 2195, 2388, 2401, 2422, 2451, 2840, 3198, 3210, 3491, 3819, 3827, 3836, 4097, 4170, 4266, 4272, 4482, 4776, 4986, 5179], 'receptor': [2, 205, 1029, 3820], '(TCR)': [3, 206], 'signaling': [4, 68, 99, 176, 207, 271, 302, 379, 532, 1146, 1255, 1998, 2317, 2342, 2372, 2429, 2458, 2920, 3087, 3323, 3937, 4046, 4789, 5108, 5133, 5163], 'enhances': [5, 69, 208, 272, 2318, 5109], 'β1,6GlcNAc-branching': [6, 36, 209, 239], 'in': [7, 76, 90, 153, 159, 210, 279, 293, 356, 362, 418, 708, 755, 983, 1113, 1125, 1230, 1377, 1424, 1470, 1693, 1748, 1751, 1816, 2000, 2003, 2237, 2326, 2386, 2469, 2496, 2517, 2520, 2576, 2705, 2756, 2778, 2798, 2815, 2829, 2835, 2959, 2996, 3067, 3209, 3499, 3546, 3774, 3904, 3916, 4021, 4168, 4215, 4261, 4484, 4539, 4542, 4607, 4791, 4794, 5028, 5117, 5177], 'N-glycans,': [8, 211, 2707], 'a': [9, 212, 412, 761, 1802, 1817, 1823, 2024, 2415, 2794, 2873, 2922, 3038, 3203, 3552, 4593, 4608, 4614, 4815], 'phenotype': [10, 213, 2505, 2823], 'that': [11, 66, 108, 150, 174, 214, 269, 311, 353, 377, 764, 1807, 1826, 1927, 2315, 2370, 2418, 2456, 2503, 2654, 2709, 2770, 2987, 3025, 3073, 3555, 4598, 4617, 4718, 5106, 5161], 'promotes': [12, 215, 2839], 'growth': [13, 199, 216, 402, 1068, 1143, 1387, 1476, 1489, 2196, 2392, 2423, 3859, 3934, 4178, 4267, 4280, 4987, 5183], 'arrest': [14, 217, 1145, 2393, 3936, 5184], 'and': [15, 61, 74, 85, 111, 121, 126, 135, 155, 191, 201, 218, 264, 277, 288, 314, 324, 329, 338, 358, 394, 404, 409, 561, 775, 1118, 1139, 1144, 1186, 1242, 1253, 1290, 1299, 1308, 1433, 1484, 1504, 1510, 1596, 1612, 1705, 1743, 1798, 1800, 1813, 1844, 1860, 1991, 1994, 2010, 2031, 2043, 2113, 2126, 2131, 2142, 2164, 2174, 2179, 2350, 2361, 2363, 2390, 2408, 2424, 2434, 2446, 2486, 2522, 2540, 2548, 2559, 2563, 2663, 2669, 2679, 2682, 2691, 2781, 2914, 2947, 2984, 3000, 3007, 3032, 3045, 3050, 3052, 3081, 3096, 3107, 3200, 3352, 3566, 3909, 3930, 3935, 3977, 4033, 4044, 4081, 4090, 4099, 4224, 4275, 4295, 4301, 4387, 4403, 4496, 4534, 4589, 4591, 4604, 4635, 4651, 4782, 4785, 4801, 4822, 4834, 4904, 4917, 4922, 4933, 4955, 4965, 4970, 5141, 5152, 5154, 5181], 'inhibits': [16, 140, 219, 343, 573, 776, 3364, 3567], 'autoimmunity': [17, 220, 1992, 2878, 4783], 'by': [18, 37, 47, 97, 143, 192, 221, 240, 250, 300, 346, 395, 569, 948, 1198, 1256, 1265, 1478, 1486, 1494, 1622, 1627, 1697, 1811, 1829, 1840, 1941, 2147, 2394, 2615, 2660, 2664, 2927, 2977, 3048, 3063, 3084, 3360, 3739, 3989, 4047, 4056, 4269, 4277, 4285, 4413, 4418, 4488, 4602, 4620, 4631, 4732, 4938, 5185], 'increasing': [19, 136, 222, 339, 1300, 4091], 'surface': [20, 195, 223, 398, 420, 753, 1131, 1383, 1435, 2013, 2029, 2402, 2667, 2841, 2955, 3211, 3544, 3922, 4174, 4226, 4804, 4820], 'retention': [21, 224, 1132, 2030, 2448, 2668, 2842, 3923, 4821], 'of': [22, 51, 72, 83, 166, 225, 254, 275, 286, 369, 414, 536, 546, 558, 564, 706, 767, 942, 951, 966, 974, 1014, 1060, 1136, 1233, 1238, 1385, 1496, 1528, 1731, 1735, 1795, 1850, 1923, 2020, 2027, 2117, 2124, 2128, 2181, 2229, 2232, 2320, 2336, 2357, 2397, 2437, 2463, 2467, 2554, 2610, 2618, 2657, 2671, 2676, 2689, 2772, 2793, 2843, 2877, 2908, 2918, 2944, 2967, 2972, 2980, 3035, 3058, 3076, 3093, 3205, 3327, 3337, 3349, 3355, 3497, 3558, 3733, 3742, 3757, 3765, 3805, 3851, 3927, 4024, 4029, 4176, 4287, 4319, 4522, 4526, 4586, 4641, 4714, 4811, 4818, 4908, 4915, 4919, 4972, 5020, 5023, 5111, 5127, 5148], 'cytotoxic': [23, 226, 1072, 3863], 'lymphocyte': [25, 228, 1074, 3865], 'antigen-4': [26, 229, 1075, 3866], '(CTLA-4)': [27, 230], 'via': [28, 231, 1390, 1846, 2776, 4181, 4637], 'interactions': [29, 232], 'with': [30, 78, 100, 233, 281, 303, 540, 1022, 1274, 1293, 1745, 2328, 2481, 2527, 2686, 2767, 3005, 3016, 3037, 3331, 3813, 4065, 4084, 4536, 5119], 'galectins.': [31, 234], 'N-Acetylglucosaminyltransferase': [32, 235], 'V': [33, 236, 1505, 4296], '(MGAT5)': [34, 237], 'mediates': [35, 238], 'transferring': [38, 241], 'N-acetylglucosamine': [39, 242, 1599, 4390], '(GlcNAc)': [40, 243], 'from': [41, 244, 1600, 2696, 4391], 'UDP-GlcNAc': [42, 131, 145, 167, 245, 334, 348, 370, 1532, 1601, 1934, 1943, 2006, 2358, 2438, 2545, 2568, 2619, 2683, 2981, 3082, 4323, 4392, 4725, 4734, 4797, 5149], 'to': [43, 147, 163, 168, 186, 246, 350, 366, 371, 389, 534, 703, 711, 717, 757, 769, 779, 1128, 1194, 1244, 1248, 1263, 1303, 1437, 1602, 1739, 1945, 1977, 2035, 2186, 2354, 2359, 2382, 2400, 2412, 2426, 2439, 2442, 2472, 2508, 2620, 2701, 2715, 2804, 2825, 2982, 3023, 3029, 3101, 3325, 3494, 3502, 3508, 3548, 3560, 3570, 3919, 3985, 4035, 4039, 4054, 4094, 4228, 4393, 4530, 4736, 4768, 4826, 4977, 5145, 5150, 5173], 'N-glycan': [44, 247, 1835, 3078, 4626], 'substrates': [45, 248], 'produced': [46, 249, 1621, 4412], 'the': [48, 88, 183, 251, 291, 386, 544, 552, 555, 562, 570, 949, 972, 1184, 1187, 1231, 1279, 1284, 1294, 1386, 1497, 1605, 1841, 1852, 1978, 2036, 2122, 2139, 2182, 2379, 2440, 2450, 2470, 2482, 2487, 2577, 2785, 2816, 2821, 2928, 2933, 2949, 2970, 3335, 3343, 3346, 3353, 3361, 3740, 3763, 3975, 3978, 4022, 4070, 4075, 4085, 4177, 4288, 4396, 4632, 4643, 4769, 4827, 4913, 4930, 4973, 5170], 'sequential': [49, 252, 2001, 4792], 'action': [50, 253, 2123, 4914], 'Golgi': [52, 255, 1499, 2039, 2234, 2323, 2376, 2441, 2471, 2484, 2489, 2579, 4290, 4830, 5025, 5114, 5167], 'α1,2-mannosidase': [53, 57, 256, 260], 'I': [54, 257, 2041, 4832], '(MIa,b,c),': [55, 258], 'MGAT1,': [56, 259], 'II': [58, 261, 2044, 4835], '(MII,': [59, 262], 'IIx),': [60, 263], 'MGAT2.': [62, 86, 265, 289], 'Here': [63, 266, 2312, 2453, 5103], 'we': [64, 267, 2313, 2454, 5104], 'report': [65, 268, 2314, 5105], 'TCR': [67, 98, 175, 270, 301, 378, 1185, 1228, 1982, 1997, 2017, 2316, 2341, 2371, 2428, 2457, 2493, 2514, 2661, 2919, 3976, 4019, 4773, 4788, 4808, 5107, 5132, 5162], 'mRNA': [70, 157, 184, 273, 360, 387, 2380, 2461, 2477, 2518, 2916, 5171], 'levels': [71, 82, 158, 274, 285, 361, 1384, 2381, 2519, 4175, 5172], 'MIa,b,c': [73, 276], 'MII,IIx': [75, 278], 'parallel': [77, 280, 2327, 5118], 'MGAT5,': [79, 133, 148, 282, 336, 351, 2570, 2909], 'whereas': [80, 283, 1067, 2150, 3011, 3858, 4941], 'limiting': [81, 144, 284, 347, 1382, 1942, 2988, 4173, 4733], 'MGAT1': [84, 120, 137, 154, 287, 323, 340, 357, 2521, 2558, 2611, 2973, 2999], 'Blocking': [87, 290], 'increase': [89, 292, 2355, 2826, 5146], 'MI': [91, 110, 294, 313, 2110, 2154, 2485, 2497, 2796, 2810, 4901, 4945], 'or': [92, 102, 295, 305, 2193, 2345, 2498, 4984, 5136], 'MII': [93, 112, 296, 315, 2114, 2167, 2490, 2499, 2713, 2774, 4905, 4958], 'enzyme': [94, 297, 1926, 2500, 4717], 'activity': [95, 113, 298, 316, 2331, 2501, 2714, 2811, 2990, 5122], 'induced': [96, 299], 'deoxymannojirimycin': [101, 304], 'swainsonine,': [103, 306], 'respectively,': [104, 134, 307, 337, 3010], 'limits': [105, 308], 'β1,6GlcNAc-branching,': [106, 309], 'suggesting': [107, 149, 310, 352, 2571, 2708, 2986], 'enhanced': [109, 312, 704, 1698, 1810, 2809, 3495, 4489, 4601], 'are': [114, 317, 1624, 2046, 2145, 2176, 2549, 2699, 2962, 3002, 4415, 4837, 4936, 4967], 'both': [115, 318, 2177, 2779, 4968], 'required': [116, 319, 2047, 2120, 2332, 2507, 2551, 2824, 4838, 4911, 5123], 'for': [117, 130, 320, 333, 554, 944, 1116, 1431, 1633, 1856, 1933, 2048, 2121, 2333, 2552, 2567, 2574, 2717, 2936, 2965, 2993, 3041, 3090, 3345, 3735, 3907, 4222, 4424, 4647, 4724, 4839, 4912, 5124], 'this': [118, 321, 1833, 2504, 2718, 2752, 2937, 4624], 'phenotype.': [119, 322], 'MGAT2': [122, 156, 325, 359, 2523, 2560, 3001], 'have': [123, 326, 1077, 2187, 2240, 2561, 3868, 4978, 5031], 'an': [124, 327, 963, 1728, 1925, 1929, 2330, 3754, 4519, 4716, 4720, 5121], '∼250-': [125, 328], '∼20-fold': [127, 330], 'higher': [128, 331], 'affinity': [129, 332, 1430, 1631, 3040, 3060, 4221, 4422], 'than': [132, 335, 1935, 2569, 4726], 'expression': [138, 341, 705, 2319, 2433, 2462, 2478, 2534, 2971, 3075, 3496, 5110], 'paradoxically': [139, 342, 1937, 4728], 'β1,6GlcNAc': [141, 189, 344, 392, 1939, 2008, 4730, 4799], 'branching': [142, 345, 1127, 1422, 1469, 1491, 1750, 1837, 1940, 2022, 2050, 2192, 2385, 2396, 2445, 2614, 2828, 2834, 2946, 2976, 3918, 4213, 4260, 4282, 4541, 4628, 4731, 4813, 4841, 4983, 5176], 'supply': [146, 349, 1527, 1944, 2356, 2436, 2617, 4318, 4735, 5147], 'restricted': [151, 354], 'changes': [152, 355, 417, 1124, 2516, 3208, 3915], 'TCR-stimulated': [160, 363], 'cells': [161, 364, 1289, 1753, 2239, 2695, 2759, 2801, 2838, 4080, 4544, 5030], 'serves': [162, 365], 'enhance': [164, 367, 2383, 2473, 2509, 5174], 'availability': [165, 368, 2979], 'MGAT5.': [169, 372], 'Together,': [170, 373], 'these': [171, 374, 1137, 3026, 3928], 'data': [172, 375, 2015, 2368, 3071, 4806, 5159], 'suggest': [173, 376, 2369, 3072, 5160], 'differentially': [177, 380, 1129, 2373, 2459, 3920, 5164], 'regulates': [178, 381, 765, 1473, 2374, 2420, 2460, 3556, 4264, 5165], 'multiple': [179, 382, 1239, 1732, 1804, 2375, 2464, 3077, 4030, 4523, 4595, 5166], 'N-glycan-processing': [180, 383], 'enzymes': [181, 384, 2144, 2377, 4935, 5168], 'at': [182, 385, 1278, 1283, 2378, 2449, 4069, 4074, 5169], 'level': [185, 388], 'cooperatively': [187, 390], 'promote': [188, 391, 2364, 2443, 5155], 'branching,': [190, 393, 977, 2009, 3095, 3768, 4800], 'extension,': [193, 396, 2665], 'CTLA-4': [194, 397, 1389, 1429, 1989, 2012, 2028, 2409, 2447, 2666, 2844, 2954, 4180, 4220, 4780, 4803, 4819], 'expression,': [196, 399, 2352, 5143], 'arrest,': [200, 403], 'self-tolerance.': [202, 405], 'IntroductionT': [406, 3197], 'activation': [408, 531, 1254, 1307, 1482, 3199, 3322, 4045, 4098, 4273], 'differentiation': [410, 701, 1310, 3201, 3492, 4101], 'induce': [411, 3202], 'number': [413, 950, 1013, 3204, 3741, 3804], 'functionally': [415, 3206], 'important': [416, 3207], 'N-glycosylation': [421, 3212], '(1.Demetriou': [422, 1311, 1711, 3111, 3213, 4102, 4502], 'M.': [423, 425, 448, 464, 468, 470, 609, 611, 675, 681, 781, 783, 810, 907, 929, 995, 1093, 1158, 1207, 1312, 1314, 1337, 1355, 1404, 1450, 1544, 1576, 1646, 1652, 1712, 1714, 1769, 1873, 1905, 1958, 2069, 2204, 2254, 2591, 2635, 2727, 2856, 3112, 3114, 3129, 3133, 3150, 3180, 3214, 3216, 3239, 3255, 3259, 3261, 3400, 3402, 3466, 3472, 3572, 3574, 3601, 3698, 3720, 3786, 3884, 3949, 3998, 4103, 4105, 4128, 4146, 4195, 4241, 4335, 4367, 4437, 4443, 4503, 4505, 4560, 4664, 4696, 4749, 4860, 4995, 5045], 'Granovsky': [424, 782, 809, 1313, 1713, 3113, 3215, 3573, 3600, 4104, 4504], 'Quaggin': [426, 784, 1315, 1715, 3115, 3217, 3575, 4106, 4506], 'S.': [427, 785, 833, 873, 877, 927, 1316, 1673, 1716, 2077, 2290, 2294, 3116, 3135, 3174, 3218, 3576, 3624, 3664, 3668, 3718, 4107, 4464, 4507, 4868, 5081, 5085], 'Dennis': [428, 445, 786, 815, 996, 1094, 1159, 1317, 1334, 1405, 1451, 1545, 1573, 1717, 1874, 1902, 1959, 2592, 2636, 2857, 3117, 3136, 3159, 3219, 3236, 3577, 3606, 3787, 3885, 3950, 4108, 4125, 4196, 4242, 4336, 4364, 4508, 4665, 4693, 4750], 'J.W.': [429, 446, 787, 816, 997, 1095, 1160, 1318, 1335, 1406, 1452, 1546, 1574, 1718, 1875, 1903, 1960, 2593, 2637, 2858, 3118, 3137, 3160, 3220, 3237, 3578, 3607, 3788, 3886, 3951, 4109, 4126, 4197, 4243, 4337, 4365, 4509, 4666, 4694, 4751], 'Nature.': [430, 788, 1319, 1719, 3119, 3221, 3579, 4110, 4510], '2001;': [431, 789, 1320, 1720, 2102, 2220, 2743, 3120, 3222, 3580, 4111, 4511, 4893, 5011], '409:': [432, 790, 1321, 1721, 3121, 3223, 3581, 4112, 4512], '733-739Crossref': [433, 791, 1322, 1722, 3122, 3224, 3582, 4113, 4513], 'PubMed': [434, 456, 492, 524, 603, 627, 659, 694, 746, 792, 821, 845, 863, 897, 919, 935, 1007, 1105, 1170, 1219, 1323, 1345, 1367, 1416, 1462, 1518, 1556, 1588, 1665, 1683, 1723, 1781, 1885, 1917, 1970, 2057, 2094, 2105, 2223, 2278, 2307, 2603, 2647, 2746, 2868, 2901, 3123, 3144, 3166, 3192, 3225, 3247, 3283, 3315, 3394, 3418, 3450, 3485, 3537, 3583, 3612, 3636, 3654, 3688, 3710, 3726, 3798, 3896, 3961, 4010, 4114, 4136, 4158, 4207, 4253, 4309, 4347, 4379, 4456, 4474, 4514, 4572, 4676, 4708, 4761, 4848, 4885, 4896, 5014, 5069, 5098], 'Scopus': [435, 457, 493, 525, 604, 628, 660, 695, 747, 793, 822, 846, 864, 898, 920, 936, 1008, 1106, 1171, 1220, 1324, 1346, 1368, 1417, 1463, 1519, 1557, 1589, 1666, 1724, 1782, 1886, 1918, 1971, 2058, 2095, 2106, 2224, 2279, 2308, 2604, 2648, 2747, 2869, 2902, 3124, 3145, 3167, 3193, 3226, 3248, 3284, 3316, 3395, 3419, 3451, 3486, 3538, 3584, 3613, 3637, 3655, 3689, 3711, 3727, 3799, 3897, 3962, 4011, 4115, 4137, 4159, 4208, 4254, 4310, 4348, 4380, 4457, 4515, 4573, 4677, 4709, 4762, 4849, 4886, 4897, 5015, 5070, 5099], '(729)': [436, 794, 1325, 1725, 3125, 3227, 3585, 4116, 4516], 'Google': [437, 459, 495, 527, 606, 630, 662, 697, 749, 795, 824, 848, 866, 900, 922, 938, 1010, 1108, 1173, 1222, 1326, 1348, 1370, 1419, 1465, 1521, 1559, 1591, 1668, 1684, 1726, 1784, 1888, 1920, 1973, 2060, 2097, 2108, 2226, 2281, 2310, 2606, 2650, 2749, 2871, 2904, 3126, 3147, 3169, 3195, 3228, 3250, 3286, 3318, 3397, 3421, 3453, 3488, 3540, 3586, 3615, 3639, 3657, 3691, 3713, 3729, 3801, 3899, 3964, 4013, 4117, 4139, 4161, 4210, 4256, 4312, 4350, 4382, 4459, 4475, 4517, 4575, 4679, 4711, 4764, 4851, 4888, 4899, 5017, 5072, 5101], 'Scholar,': [438, 460, 496, 607, 631, 663, 796, 825, 849, 867, 901, 923, 1327, 1349, 1560, 1669, 1889, 2061, 2098, 2282, 3127, 3148, 3170, 3229, 3251, 3287, 3398, 3422, 3454, 3587, 3616, 3640, 3658, 3692, 3714, 4118, 4140, 4351, 4460, 4680, 4852, 4889, 5073], '2.Morgan': [439, 1328, 3230, 4119], 'R.': [440, 879, 1329, 1572, 1901, 2202, 2725, 3158, 3231, 3670, 4120, 4363, 4692, 4993], 'Gao': [441, 1330, 1569, 1762, 1898, 3232, 4121, 4360, 4553, 4689], 'G.': [442, 1331, 1570, 1763, 1899, 2200, 2723, 3233, 4122, 4361, 4554, 4690, 4991], 'Pawling': [443, 805, 1332, 1758, 3153, 3234, 3596, 4123, 4549], 'J.': [444, 451, 487, 506, 585, 613, 616, 648, 665, 728, 806, 827, 831, 834, 886, 908, 1208, 1333, 1340, 1356, 1577, 1636, 1674, 1759, 1770, 1906, 2075, 2214, 2267, 2737, 3138, 3152, 3154, 3235, 3242, 3278, 3297, 3376, 3404, 3407, 3439, 3456, 3519, 3597, 3618, 3622, 3625, 3677, 3699, 3999, 4124, 4131, 4147, 4368, 4427, 4465, 4550, 4561, 4697, 4866, 5005, 5058], 'Demetriou': [447, 906, 928, 994, 1092, 1157, 1206, 1336, 1354, 1403, 1449, 1543, 1575, 1768, 1872, 1904, 1957, 2590, 2634, 2855, 3238, 3697, 3719, 3785, 3883, 3948, 3997, 4127, 4145, 4194, 4240, 4334, 4366, 4559, 4663, 4695, 4748], 'Li': [449, 1338, 3240, 4129], 'B.': [450, 881, 1339, 3241, 3672, 4130], 'Immunol.': [452, 488, 520, 599, 742, 930, 1341, 3243, 3279, 3311, 3390, 3533, 3721, 4132], '2004;': [453, 818, 889, 1342, 3244, 3609, 3680, 4133], '173:': [454, 1343, 3245, 4134], '7200-7208Crossref': [455, 1344, 3246, 4135], '(130)': [458, 1347, 3249, 4138], '3.Comelli': [461, 3252], 'E.M.': [462, 514, 593, 736, 3253, 3305, 3384, 3527], 'Sutton-Smith': [463, 2068, 2203, 2253, 2726, 3254, 4859, 4994, 5044], 'Yan': [465, 3256], 'Q.': [466, 3257], 'Amado': [467, 3258], 'Panico': [469, 3260], 'Gilmartin': [471, 3262], 'T.': [472, 474, 667, 673, 677, 679, 1638, 1644, 1648, 1650, 1765, 2206, 2729, 3263, 3265, 3458, 3464, 3468, 3470, 4429, 4435, 4439, 4441, 4556, 4997], 'Whisenant': [473, 3264], 'Lanigan': [475, 3266], 'C.M.': [476, 635, 3267, 3426], 'Head': [477, 3268], 'S.R.': [478, 633, 3269, 3424], 'Goldberg': [479, 3270], 'D.': [480, 2198, 2721, 3271, 4989], 'Morris': [481, 2072, 2209, 2255, 2732, 3272, 4863, 5000, 5046], 'H.R.': [482, 2073, 2256, 3273, 4864, 5047], 'Dell': [483, 2070, 2211, 2257, 2734, 3274, 4861, 5002, 5048], 'A.': [484, 829, 925, 989, 1087, 1152, 1398, 1444, 1538, 1562, 1757, 1867, 1891, 1952, 2071, 2079, 2100, 2212, 2258, 2266, 2585, 2629, 2735, 2850, 2886, 2888, 3178, 3275, 3620, 3716, 3780, 3878, 3943, 4189, 4235, 4329, 4353, 4548, 4658, 4682, 4743, 4862, 4870, 4891, 5003, 5049, 5057], 'Paulson': [485, 3276], 'J.C.': [486, 3277], '2006;': [489, 2091, 3280, 4882], '177:': [490, 3281], '2431-2440Crossref': [491, 3282], '(97)': [494, 3285], '4.Toscano': [497, 3288], 'M.A.': [498, 577, 720, 3289, 3368, 3511], 'Bianco': [499, 578, 721, 3290, 3369, 3512], 'G.A.': [500, 518, 579, 597, 722, 740, 3291, 3309, 3370, 3388, 3513, 3531], 'Ilarregui': [501, 580, 723, 3292, 3371, 3514], 'J.M.': [502, 581, 724, 2882, 3293, 3372, 3515], 'Croci': [503, 582, 725, 3294, 3373, 3516], 'D.O.': [504, 583, 726, 3295, 3374, 3517], 'Correale': [505, 584, 727, 3296, 3375, 3518], 'Hernandez': [507, 586, 729, 3298, 3377, 3520], 'J.D.': [508, 587, 730, 2083, 3182, 3299, 3378, 3521, 4874], 'Zwirner': [509, 588, 731, 3300, 3379, 3522], 'N.W.': [510, 589, 732, 3301, 3380, 3523], 'Poirier': [511, 590, 733, 3302, 3381, 3524], 'F.': [512, 591, 685, 734, 883, 1656, 3303, 3382, 3476, 3525, 3674, 4447], 'Riley': [513, 592, 735, 3304, 3383, 3526], 'Baum': [515, 594, 614, 737, 854, 3306, 3385, 3405, 3528, 3645], 'L.G.': [516, 595, 615, 738, 855, 3307, 3386, 3406, 3529, 3646], 'Rabinovich': [517, 596, 739, 3308, 3387, 3530], 'Nat.': [519, 598, 741, 3161, 3310, 3389, 3532], '2007;': [521, 600, 743, 837, 911, 999, 1097, 1162, 1211, 1359, 1408, 1454, 1548, 1580, 1773, 1877, 1909, 1962, 2270, 2595, 2639, 2860, 3312, 3391, 3534, 3628, 3702, 3790, 3888, 3953, 4002, 4150, 4199, 4245, 4339, 4371, 4564, 4668, 4700, 4753, 5061], '8:': [522, 601, 744, 3313, 3392, 3535], '825-834Crossref': [523, 602, 745, 3314, 3393, 3536], '(498)': [526, 605, 748, 3317, 3396, 3539], 'Scholar).': [528, 698, 750, 939, 1011, 1109, 1223, 1371, 1420, 1466, 1592, 1685, 1785, 1921, 1974, 2109, 2227, 2311, 2607, 2651, 2750, 2905, 3196, 3319, 3489, 3541, 3730, 3802, 3900, 4014, 4162, 4211, 4257, 4383, 4476, 4576, 4712, 4765, 4900, 5018, 5102], 'For': [529, 3320], 'example,': [530, 3321], 'leads': [533, 702, 3324, 3493], 'replacement': [535, 3326], 'α2,6-linked': [537, 566, 3328, 3357], 'sialic': [538, 567, 3329, 3358], 'acid': [539, 568, 3330, 3359], 'α1,3-linked': [541, 3332], 'galactose': [542, 3333], 'on': [543, 2190, 2348, 3334, 4981, 5139], 'termini': [545, 3336], 'N-acetyllactosamine': [547, 758, 981, 3338, 3549, 3772], '(Galβ1,4GlcNAc)': [548, 3339], 'units.': [549, 3340], 'N-Acetyllactosamine': [550, 3341], 'is': [551, 946, 1180, 1492, 1808, 1822, 1827, 1838, 2184, 2506, 2535, 2753, 2765, 2784, 2802, 2819, 2991, 3021, 3088, 3342, 3737, 3971, 4283, 4599, 4613, 4618, 4629, 4975], 'ligand': [553, 3344], 'galectin': [556, 574, 1114, 1260, 1295, 3042, 3061, 3347, 3365, 3905, 4051, 4086], 'family': [557, 3348], 'carbohydrate-binding': [559, 3350], 'proteins,': [560, 3351], 'addition': [563, 2034, 3354, 4825], 'terminal': [565, 3356], 'ST6Gal1': [571, 707, 3362, 3498], 'transferase': [572, 3363], 'binding': [575, 1225, 2411, 3366, 4016], '(4.Toscano': [576, 3367], '5.Amano': [608, 3399], 'Galvan': [610, 3401], 'He': [612, 3403], 'Biol.': [617, 649, 835, 859, 887, 909, 1209, 1357, 1578, 1675, 1771, 1907, 2268, 3140, 3408, 3440, 3626, 3650, 3678, 3700, 4000, 4148, 4369, 4466, 4562, 4698, 5059], 'Chem.': [618, 650, 836, 888, 910, 1210, 1358, 1579, 1676, 1772, 1908, 2269, 3409, 3441, 3627, 3679, 3701, 4001, 4149, 4370, 4467, 4563, 4699, 5060], '2003;': [619, 3410], '278:': [620, 3411], '7469-7475Abstract': [621, 3412], 'Full': [622, 624, 654, 656, 840, 842, 892, 894, 914, 916, 1002, 1004, 1100, 1102, 1165, 1167, 1214, 1216, 1362, 1364, 1411, 1413, 1457, 1459, 1551, 1553, 1583, 1585, 1680, 1776, 1778, 1880, 1882, 1912, 1914, 1965, 1967, 2273, 2275, 2598, 2600, 2642, 2644, 2863, 2865, 3187, 3189, 3413, 3415, 3445, 3447, 3631, 3633, 3683, 3685, 3705, 3707, 3793, 3795, 3891, 3893, 3956, 3958, 4005, 4007, 4153, 4155, 4202, 4204, 4248, 4250, 4342, 4344, 4374, 4376, 4471, 4567, 4569, 4671, 4673, 4703, 4705, 4756, 4758, 5064, 5066], 'Text': [623, 625, 655, 657, 841, 843, 893, 895, 915, 917, 1003, 1005, 1101, 1103, 1166, 1168, 1215, 1217, 1363, 1365, 1412, 1414, 1458, 1460, 1552, 1554, 1584, 1586, 1681, 1777, 1779, 1881, 1883, 1913, 1915, 1966, 1968, 2274, 2276, 2599, 2601, 2643, 2645, 2864, 2866, 3188, 3190, 3414, 3416, 3446, 3448, 3632, 3634, 3684, 3686, 3706, 3708, 3794, 3796, 3892, 3894, 3957, 3959, 4006, 4008, 4154, 4156, 4203, 4205, 4249, 4251, 4343, 4345, 4375, 4377, 4472, 4568, 4570, 4672, 4674, 4704, 4706, 4757, 4759, 5065, 5067], 'PDF': [626, 658, 844, 896, 918, 1006, 1104, 1169, 1218, 1366, 1415, 1461, 1555, 1587, 1682, 1780, 1884, 1916, 1969, 2277, 2602, 2646, 2867, 3191, 3417, 3449, 3635, 3687, 3709, 3797, 3895, 3960, 4009, 4157, 4206, 4252, 4346, 4378, 4473, 4571, 4675, 4707, 4760, 5068], '(188)': [629, 3420], '6.Stowell': [632, 3423], 'Arthur': [634, 3425], 'Mehta': [636, 3427], 'P.': [637, 808, 2880, 3428, 3599], 'Slanina': [638, 3429], 'K.A.': [639, 3430], 'Blixt': [640, 3431], 'O.': [641, 3432], 'Leffler': [642, 3433], 'H.': [643, 875, 1513, 2052, 2065, 2210, 2286, 2733, 2894, 3434, 3666, 4304, 4843, 4856, 5001, 5077], 'Smith': [644, 3435], 'D.F.': [645, 3436], 'Cummings': [646, 3437], 'R.D.': [647, 1671, 3438, 4462], '2008;': [651, 3442], '283:': [652, 3443], '10109-10123Abstract': [653, 3444], '(332)': [661, 3452], '7.Hirabayashi': [664, 3455], 'Hashidate': [666, 1637, 3457, 4428], 'Arata': [668, 1639, 3459, 4430], 'Y.': [669, 1640, 3460, 4431], 'Nishi': [670, 1641, 3461, 4432], 'N.': [671, 869, 1642, 3462, 3660, 4433], 'Nakamura': [672, 1643, 3463, 4434], 'Hirashima': [674, 1645, 3465, 4436], 'Urashima': [676, 1647, 3467, 4438], 'Oka': [678, 1649, 3469, 4440], 'Futai': [680, 1651, 3471, 4442], 'Muller': [682, 1653, 3155, 3473, 4444], 'W.E.': [683, 1654, 3474, 4445], 'Yagi': [684, 1655, 3475, 4446], 'Kasai': [686, 1657, 3477, 4448], 'K.': [687, 1658, 2208, 2288, 2731, 3172, 3478, 4449, 4999, 5079], 'Biochim.': [688, 1659, 3479, 4450], 'Biophys.': [689, 1660, 3480, 4451], 'Acta.': [690, 1661, 3481, 4452], '2002;': [691, 860, 1662, 2304, 3482, 3651, 4453, 5095], '1572:': [692, 1663, 3483, 4454], '232-254Crossref': [693, 1664, 3484, 4455], '(813)': [696, 1667, 3487, 4458], 'TH2': [709, 3500], 'relative': [710, 3501], 'TH1/TH17': [712, 3503], 'cells,': [713, 1177, 1292, 1427, 2172, 3069, 3504, 3968, 4083, 4218, 4963], 'thereby': [714, 1235, 3505, 4026], 'reducing': [715, 1297, 2616, 2978, 3506, 4088], 'sensitivity': [716, 3507], 'galectin-1-induced': [718, 3509], 'apoptosis(4.Toscano': [719, 3510], 'Galectins': [751, 3542], 'bind': [752, 3543], 'glycoproteins': [754, 768, 945, 1025, 2403, 3036, 3545, 3559, 3736, 3816], 'proportion': [756, 3547], 'content,': [759, 3550], 'forming': [760, 1608, 2414, 3551, 4399], 'molecular': [762, 2416, 2934, 3553], 'lattice': [763, 1296, 2417, 3554, 4087], 'distribution': [766, 3557], 'membrane': [770, 1024, 1196, 1374, 3561, 3815, 3987, 4165], 'microdomains': [771, 1251, 3562, 4042], '(i.e.': [772, 954, 1063, 1133, 1506, 3043, 3563, 3745, 3854, 3924, 4297], 'lipid': [773, 1038, 1250, 3564, 3829, 4041], 'rafts)': [774, 3565], 'their': [777, 1529, 3568, 4320], 'loss': [778, 1436, 2180, 2719, 3569, 4227, 4971], 'endocytosis(1.Demetriou': [780, 3571], '8.Partridge': [797, 3588], 'E.A.': [798, 987, 1085, 1150, 1396, 1442, 1536, 1865, 1950, 2583, 2627, 2848, 3589, 3778, 3876, 3941, 4187, 4233, 4327, 4656, 4741], 'Le': [799, 3590], 'Roy': [800, 878, 3591, 3669], 'C.': [801, 1767, 2264, 2292, 3592, 4558, 5055, 5083], 'Di': [802, 3593], 'Guglielmo': [803, 3594], 'G.M.': [804, 3595], 'Cheung': [807, 3598], 'Nabi': [811, 3130, 3602], 'I.R.': [812, 3131, 3603], 'Wrana': [813, 3604], 'J.L.': [814, 2300, 3605, 5091], 'Science.': [817, 2303, 2897, 3608, 5094], '306:': [819, 3610], '120-124Crossref': [820, 3611], '(583)': [823, 3614], '9.Nieminen': [826, 3617], 'Kuno': [828, 3619], 'Hirabayashi': [830, 3621], 'Sato': [832, 3623], '282:': [838, 912, 1212, 1360, 1581, 1774, 1910, 2271, 3629, 3703, 4003, 4151, 4372, 4565, 4701, 5062], '1374-1383Abstract': [839, 3630], '(184)': [847, 3638], '10.Brewer': [850, 3641], 'C.F.': [851, 885, 3642, 3676], 'Miceli': [852, 3643], 'M.C.': [853, 3644], 'Curr.': [856, 3647], 'Opin.': [857, 3648], 'Struct.': [858, 3649], '12:': [861, 3652], '616-623Crossref': [862, 3653], '(371)': [865, 3656], '11.Ahmad': [868, 3659], 'Gabius': [870, 3661], 'H.J.': [871, 3662], 'André': [872, 3663], 'Kaltner': [874, 3665], 'Sabesan': [876, 3667], 'Liu': [880, 3671], 'Macaluso': [882, 3673], 'Brewer': [884, 3675], '279:': [890, 3681], '10841-10847Abstract': [891, 3682], '(422)': [899, 3690], '12.Chen': [902, 1350, 3693, 4141], 'I.J.': [903, 1203, 1351, 1568, 1761, 1897, 3694, 3994, 4142, 4359, 4552, 4688], 'Chen': [904, 1204, 1352, 1567, 1760, 1896, 3695, 3995, 4143, 4358, 4551, 4687], 'H.L.': [905, 1205, 1353, 3696, 3996, 4144], '35361-35372Abstract': [913, 1213, 1361, 3704, 4004, 4152], '(110)': [921, 1221, 1369, 3712, 4012, 4160], '13.Grigorian': [924, 3715], 'Torossian': [926, 3717], 'Rev.': [931, 3722], '2009;': [932, 3723], '230:': [933, 3724], '232-246Crossref': [934, 3725], '(102)': [937, 3728], 'Binding': [940, 3731], 'avidity': [941, 1115, 3732, 3906], 'galectins': [943, 1432, 1634, 3734, 4223, 4425], 'regulated': [947, 1493, 1839, 3056, 3738, 4284, 4630], 'attached': [952, 2399, 3743], 'N-glycans': [953, 1079, 1471, 1603, 1615, 1620, 2133, 2398, 2659, 3047, 3744, 3870, 4262, 4394, 4406, 4411, 4924], 'N': [955, 3746], '=': [956, 2156, 2159, 2162, 3747, 4947, 4950, 4953], 'occupied': [957, 3748], 'N-X-(S/T)': [958, 1015, 1061, 3749, 3806, 3852], 'sites,': [959, 3750], 'X': [960, 3751], '≠': [961, 3752], 'P),': [962, 3753], 'encoded': [964, 2146, 3755, 4937], 'feature': [965, 3756], 'protein': [967, 1054, 3758, 3845], 'sequences,': [968, 3759], 'as': [969, 971, 1523, 1525, 1695, 2023, 2405, 2546, 3104, 3760, 3762, 4314, 4316, 4486, 4814], 'well': [970, 1524, 3761, 4315], 'degree': [973, 3764], 'Golgi-mediated': [975, 1123, 3766, 3914], 'GlcNAc': [976, 1126, 1421, 1468, 1749, 1836, 2021, 2049, 2191, 2365, 2384, 2444, 2474, 2510, 2613, 2622, 2827, 2833, 2945, 2975, 2997, 3094, 3767, 3917, 4212, 4259, 4540, 4627, 4812, 4840, 4982, 5156, 5175], 'which': [978, 3769], 'together': [979, 3770], 'determine': [980, 3771], 'content': [982, 3773], 'glycoproteins(14.Lau': [984, 3775], 'K.S.': [985, 1083, 1148, 1394, 1440, 1534, 1863, 1948, 2581, 2625, 2846, 3776, 3874, 3939, 4185, 4231, 4325, 4654, 4739], 'Partridge': [986, 1084, 1149, 1395, 1441, 1535, 1864, 1949, 2582, 2626, 2847, 3777, 3875, 3940, 4186, 4232, 4326, 4655, 4740], 'Grigorian': [988, 1086, 1151, 1397, 1443, 1537, 1756, 1866, 1951, 2584, 2628, 2849, 3779, 3877, 3942, 4188, 4234, 4328, 4547, 4657, 4742], 'Silvescu': [990, 1088, 1153, 1399, 1445, 1539, 1868, 1953, 2586, 2630, 2851, 3781, 3879, 3944, 4190, 4236, 4330, 4659, 4744], 'C.I.': [991, 1089, 1154, 1400, 1446, 1540, 1869, 1954, 2587, 2631, 2852, 3782, 3880, 3945, 4191, 4237, 4331, 4660, 4745], 'Reinhold': [992, 1090, 1155, 1401, 1447, 1541, 1870, 1955, 2588, 2632, 2853, 3783, 3881, 3946, 4192, 4238, 4332, 4661, 4746], 'V.N.': [993, 1091, 1156, 1402, 1448, 1542, 1871, 1956, 2589, 2633, 2854, 3784, 3882, 3947, 4193, 4239, 4333, 4662, 4747], 'Cell.': [998, 1096, 1161, 1407, 1453, 1547, 1876, 1961, 2594, 2638, 2859, 3183, 3789, 3887, 3952, 4198, 4244, 4338, 4667, 4752], '129:': [1000, 1098, 1163, 1409, 1455, 1549, 1878, 1963, 2596, 2640, 2861, 3791, 3889, 3954, 4200, 4246, 4340, 4669, 4754], '123-134Abstract': [1001, 1099, 1164, 1410, 1456, 1550, 1879, 1964, 2597, 2641, 2862, 3792, 3890, 3955, 4201, 4247, 4341, 4670, 4755], '(666)': [1009, 1107, 1172, 1418, 1464, 1558, 1887, 1972, 2605, 2649, 2870, 3800, 3898, 3963, 4209, 4255, 4349, 4678, 4763], 'The': [1012, 1110, 1786, 3803, 3901, 4577], 'sites': [1016, 1062, 3807, 3853], 'varies': [1017, 1741, 3808, 4532], 'widely': [1018, 1742, 3809, 4533], 'between': [1019, 1142, 1287, 3810, 3933, 4078], 'different': [1020, 1195, 3811, 3986], 'glycoproteins,': [1021, 3812], 'growth-promoting': [1023, 3814], '(e.g.': [1026, 1071, 3817, 3862], '(TCR))': [1030, 3821], '2The': [1031, 3822], 'abbreviations': [1032, 3823], 'used': [1033, 3824], 'are:': [1034, 3825], 'TCRT': [1035, 3826], 'receptorGEMGM1-enriched': [1037, 3828], 'microdomainsEAEexperimental': [1039, 3830], 'autoimmune': [1040, 1708, 1995, 3831, 4499, 4786], 'encephalomyelitisMIα-mannosidase': [1041, 3832], 'IMIIα-mannosidase': [1042, 3833], 'IIL-PHAleukoagglutininFITCfluorescein': [1043, 3834], 'isothiocyanateFACSfluorescence-activated': [1044, 3835], 'sorterELISAenzyme-linked': [1046, 3837], 'immunosorbent': [1047, 3838], 'assayPBMCperipheral': [1048, 3839], 'blood': [1049, 3840], 'mononuclear': [1050, 3841], 'cellMBPmyelin': [1051, 3842], 'basic': [1052, 3843], 'proteinILinterleukinIFNinterferonSWswainsonineDMNdeoxymannojirimycinMAPKmitogen-activated': [1053, 3844], 'kinase.': [1055, 3846], 'generally': [1056, 3847], 'displaying': [1057, 3848], 'large': [1058, 1111, 3849, 3902], 'numbers': [1059, 3850], 'n': [1064, 3855], '>': [1065, 3856], '5),': [1066, 3857], 'inhibitory': [1069, 3860], 'receptors': [1070, 1121, 1138, 3861, 3912, 3929], '(CTLA-4))': [1076, 3867], 'few': [1078, 3869], '(n': [1080, 3871], '≤': [1081, 3872], '4)(14.Lau': [1082, 3873], 'difference': [1112, 3903], 'high': [1117, 1630, 3059, 3908, 4421], 'low': [1119, 3910], 'multiplicity': [1120, 3911], 'allows': [1122, 3913], 'control': [1130, 3921], 'endocytosis': [1134, 1179, 1392, 1438, 3925, 3970, 4183, 4229], 'rates)': [1135, 3926], 'therefore': [1140, 3931], 'transitions': [1141, 3932], '(14.Lau': [1147, 1393, 1439, 1533, 1862, 1947, 2580, 2624, 2845, 3938, 4184, 4230, 4324, 4653, 4738], 'Scholar).In': [1174, 3965], 'resting': [1175, 2693, 3966], 'where': [1178, 3969], 'minimal,': [1181, 3972], 'galectin-3': [1182, 3973], 'binds': [1183, 3974], 'tyrosine': [1188, 3979], 'phosphatase': [1189, 3980], 'CD45': [1190, 1262, 1301, 3981, 4053, 4092], 'but': [1191, 3054, 3982], 'partitions': [1192, 1261, 3983, 4052], 'them': [1193, 3984], 'compartments': [1197, 3988], 'opposing': [1199, 1434, 3990, 4225], 'F-actin': [1200, 3991], 'targeting': [1201, 3992], '(12.Chen': [1202, 3993], 'Galectin': [1224, 4015], 'prevents': [1226, 4017], 'spontaneous': [1227, 1702, 1803, 4018, 4493, 4594], 'oligomerization': [1229, 4020], 'absence': [1232, 4023], 'antigen,': [1234, 1275, 4025, 4066], 'blocking': [1236, 2791, 4027], 'recruitment': [1237, 4028], 'adaptor': [1240, 4031], 'proteins': [1241, 4032], 'CD4-Lck': [1243, 4034], 'TCR,': [1245, 2406, 4036], 'F-actin-mediated': [1246, 1267, 4037, 4058], 'transfer': [1247, 1598, 4038, 4389], 'GM1-enriched': [1249, 4040], '(GEMs),': [1252, 4043], 'Lck.': [1257, 4048], 'In': [1258, 1832, 2033, 2137, 2170, 2339, 2512, 4049, 4623, 4824, 4928, 4961, 5130], 'parallel,': [1259, 4050], 'GEMs': [1264, 1276, 4055, 4067], 'counteracting': [1266, 4057], 'exclusion,': [1268, 4059], 'dampening': [1269, 4060], 'Lck': [1270, 4061], 'activation.': [1271, 4062], 'Upon': [1272, 4063], 'encounter': [1273, 4064], 'cluster': [1277, 4068], 'immune': [1280, 4071], 'synapse': [1281, 4072], 'formed': [1282, 4073], 'contact': [1285, 4076], 'site': [1286, 4077], 'antigen-presenting': [1291, 4082], 'TCR/CD4-Lck': [1298, 4089], 'concentration': [1302, 4093], 'dampen': [1304, 4095], 'TH1': [1309, 1987, 4100, 4778], 'After': [1372, 4163], 'activation,': [1373, 4164], 'turnover': [1375, 4166], 'increases': [1376, 1423, 2002, 2495, 2777, 2814, 2995, 4167, 4214, 4793], 'blasts,': [1380, 2389, 4171, 5180], 'markedly': [1381, 1809, 4172, 4600], 'inhibitor': [1388, 4179], 'constitutive': [1391, 4182], 'blasting': [1425, 4216], 'enhancing': [1428, 1487, 4219, 4278], 'Thus,': [1467, 4258], 'negatively': [1472, 2419, 4263], 'early': [1477, 4268], 'raising': [1479, 4270], 'thresholds': [1483, 4274], 'later': [1485, 4276], 'CTLA-4-mediated': [1488, 4279], 'arrest.GlcNAc': [1490, 4281], 'activities': [1495, 1794, 2681, 4286, 4585], 'medial': [1498, 1606, 2578, 4289, 4397], 'N-acetylglucosaminyltransferases': [1500, 4291], 'I,': [1501, 4292], 'II,': [1502, 4293], 'IV,': [1503, 4294], 'Mgat1,': [1507, 1593, 1796, 1857, 1924, 2118, 2140, 4298, 4384, 4587, 4648, 4715, 4909, 4931], 'Mgat2,': [1508, 1594, 1797, 1858, 2141, 4299, 4385, 4588, 4649, 4932], 'Mgat4,': [1509, 1595, 1859, 4300, 4386, 4650], 'Mgat5)': [1511, 4302], '(15.Schachter': [1512, 2051, 4303, 4842], 'Glycobiology.': [1514, 2053, 4305, 4844], '1991;': [1515, 2054, 4306, 4845], '1:': [1516, 2055, 4307, 4846], '453-461Crossref': [1517, 2056, 4308, 4847], '(167)': [1520, 2059, 4311, 4850], 'Scholar),': [1522, 1727, 2872, 4313, 4518], 'metabolic': [1526, 2435, 4317], 'shared': [1530, 4321], 'substrate': [1531, 2575, 4322], '16.Grigorian': [1561, 1890, 4352, 4681], 'Lee': [1563, 1892, 2889, 4354, 4683], 'S.U.': [1564, 1755, 1893, 4355, 4546, 4684], 'Tian': [1565, 1894, 4356, 4685], 'W.': [1566, 1895, 4357, 4686], 'Mendelsohn': [1571, 1900, 4362, 4691], '20027-20035Abstract': [1582, 1911, 4373, 4702], '(101)': [1590, 1919, 4381, 4710], 'Mgat5': [1597, 1623, 1799, 1861, 1946, 2143, 2362, 2468, 2680, 4388, 4414, 4590, 4652, 4737, 4934, 5153], 'transiting': [1604, 4395], 'Golgi,': [1607, 4398], 'mono-,': [1609, 4400], 'bi-,': [1610, 2129, 4401, 4920], 'tri-,': [1611, 2130, 4402, 4921], 'tetra-antennary': [1613, 2132, 4404, 4923], 'GlcNAc-branched': [1614, 2658, 2706, 4405], '(see': [1616, 2134, 4407, 4925], 'Fig.': [1617, 2135, 4408, 4926], '1A).': [1618, 2136, 4409, 4927], 'β1,6GlcNAc-branched': [1619, 2337, 2555, 4410, 5128], 'preferentially': [1625, 4416], 'extended': [1626, 4417], 'poly-N-acetyllactosamine,': [1628, 4419], 'generating': [1629, 4420], 'ligands': [1632, 3062, 4423], '(7.Hirabayashi': [1635, 4426], '17.Cummings': [1670, 4461], 'Kornfeld': [1672, 4463], '1984;': [1677, 4468], '259:': [1678, 4469], '6253-6260Abstract': [1679, 4470], 'Mgat5-deficient': [1686, 4477], '129/Sv': [1687, 4478], 'mice': [1688, 2698, 4479], 'display': [1689, 2702, 4480], 'hyperactivity': [1692, 4483], 'vivo,': [1694, 4485], 'exemplified': [1696, 3066, 4487], 'type': [1699, 3108, 4490], 'IV': [1700, 4491], 'hypersensitivity,': [1701, 4492], 'kidney': [1703, 4494], 'autoimmunity,': [1704, 2672, 3105, 4495], 'increased': [1706, 4497], 'experimental': [1707, 4498], 'encephalomyelitis': [1709, 4500], '(EAE)': [1710, 4501], 'animal': [1729, 4520], 'model': [1730, 4521], 'sclerosis.': [1733, 4524], 'Susceptibility': [1734, 4525], 'inbred': [1736, 4527], 'mouse': [1737, 4528], 'strains': [1738, 4529], 'EAE': [1740, 4531], 'correlates': [1744, 2480, 4535], 'strain-specific': [1746, 4537], 'deficiencies': [1747, 4538], '(18.Lee': [1754, 4545], 'Mozaffar': [1764, 4555], 'McKerlie': [1766, 2263, 4557, 5054], '33725-33734Abstract': [1775, 4566], '(75)': [1783, 4574], 'EAE-susceptible': [1787, 4578], 'PL/J': [1788, 4579], 'strain': [1789, 4580], 'intrinsically': [1790, 4581], 'possesses': [1791, 4582], 'reduced': [1792, 2531, 4583], 'basal': [1793, 4584], 'develops': [1801, 4592], 'sclerosis-like': [1805, 4596], 'disease': [1806, 4597], 'Mgat5+/−': [1812, 4603], 'Mgat5−/−': [1814, 4605], 'backgrounds': [1815, 4606], 'gene': [1818, 2432, 2797, 2951, 4609], 'dose-dependent': [1819, 4610], 'manner.': [1820, 4611], 'Autoimmunity': [1821, 4612], 'complex': [1824, 4615], 'trait': [1825, 4616], 'influenced': [1828, 4619], 'environmental': [1830, 4621], 'inputs.': [1831, 4622], 'regard,': [1834, 4625], 'nutrient': [1842, 4633], 'environment': [1843, 4634], 'metabolism': [1845, 4636], 'hexosamine': [1847, 1979, 4638, 4770], 'pathway': [1848, 1980, 3079, 4639, 4771], 'production': [1849, 2127, 2335, 3034, 3057, 3083, 4640, 4918, 5126], 'UDP-GlcNAc,': [1851, 4642], 'sugar': [1853, 4644], 'nucleotide': [1854, 4645], 'donor': [1855, 4646], 'Overexpression': [1922, 4713], 'has': [1928, 2343, 3013, 4719, 5134], '∼250-fold': [1930, 4721], 'lower': [1931, 2565, 4722], 'Km': [1932, 2566, 4723], 'Mgat5,': [1936, 2329, 2985, 4727, 5120], 'reduces': [1938, 2612, 2974, 4729], 'Metabolic': [1975, 4766], 'supplements': [1976, 4767], 'suppress': [1981, 4772], 'signaling,': [1983, 2662, 4774], 'activation/proliferation,': [1986, 4777], 'differentiation,': [1988, 4779], 'endocytosis,': [1990, 4781], '(EAE': [1993, 4784], 'diabetes).': [1996, 4787], 'results': [1999, 4790], 'glucose': [2004, 4795], 'flux,': [2005, 4796], 'production,': [2007, 4798], 'finally,': [2011, 4802], 'expression.These': [2014, 4805], 'implicate': [2016, 4807], 'signaling-mediated': [2018, 2494, 2515, 4809], 'enhancement': [2019, 4810], 'critical': [2025, 2874, 2942, 4816], 'regulator': [2026, 2876, 4817], 'autoimmunity.': [2032, 2427, 4823], 'Mgat': [2037, 4828], 'enzymes,': [2038, 4829], 'α-mannosidase': [2040, 2235, 2324, 4831, 5026, 5115], '(MI)': [2042, 4833], '(MII)': [2045, 4836], '19.Akama': [2062, 4853], 'T.O.': [2063, 2284, 4854, 5075], 'Nakagawa': [2064, 2285, 4855, 5076], 'Wong': [2066, 2251, 4857, 5042], 'N.K.': [2067, 2252, 4858, 5043], 'Nakayama': [2074, 4865], 'Nishimura': [2076, 2293, 4867, 5084], 'Pai': [2078, 4869], 'Moremen': [2080, 2297, 4871, 5088], 'K.W.': [2081, 2298, 4872, 5089], 'Marth': [2082, 2213, 2736, 3181, 4873, 5004], 'Fukuda': [2084, 2301, 4875, 5092], 'M.N.': [2085, 2302, 4876, 5093], 'Proc.': [2086, 2215, 2738, 4877, 5006], 'Natl.': [2087, 2216, 2739, 4878, 5007], 'Acad.': [2088, 2217, 2740, 4879, 5008], 'Sci.': [2089, 2218, 2741, 4880, 5009], 'U.S.A.': [2090, 2219, 2742, 4881, 5010], '103:': [2092, 4883], '8983-8988Crossref': [2093, 4884], '(57)': [2096, 4887], '20.Herscovics': [2099, 4890], 'Biochimie.': [2101, 4892], '83:': [2103, 4894], '757-762Crossref': [2104, 4895], '(92)': [2107, 4898], 'acts': [2111, 2115, 4902, 4906], 'upstream': [2112, 2466, 4903], 'downstream': [2116, 2621, 2917, 4907], 'steps': [2119, 4910], 'Mgat2': [2125, 2351, 4916, 5142], 'mammals,': [2138, 4929], 'single': [2148, 2795, 4939], 'genes,': [2149, 2529, 4940], 'three': [2151, 2483, 2817, 4942], 'genes': [2152, 2236, 2325, 2465, 2818, 2961, 3004, 3080, 4943, 5027, 5116], 'encode': [2153, 2166, 4944, 4957], '(MIa': [2155, 4946], 'MAN1A1,': [2157, 2910, 4948], 'MIb': [2158, 4949], 'MAN1A2,': [2160, 2911, 4951], 'MIc': [2161, 4952], 'MAN1C1)': [2163, 4954], 'two': [2165, 2488, 3006, 4956], '(MAN2A1,': [2168, 4959], 'MAN2A2).': [2169, 4960], 'MAN2A1': [2173, 2780, 4964], 'MAN2A2': [2175, 2710, 2782, 2915, 4966], 'expressed,': [2178, 4969], 'former': [2183, 4974], 'reported': [2185, 2700, 4976], 'little': [2188, 2344, 2703, 4979, 5135], 'effect': [2189, 2347, 4980, 5138], '(21.Chui': [2197, 2720, 4988], 'Sellakumar': [2199, 2722, 4990], 'Green': [2201, 2724, 4992], 'McQuistan': [2205, 2728, 4996], 'Marek': [2207, 2730, 4998], '98:': [2221, 2744, 5012], '1142-1147Crossref': [2222, 2745, 5013], '(179)': [2225, 2748, 5016], 'Effects': [2228, 5019], 'targeted': [2230, 5021], 'deletion': [2231, 5022], 'other': [2233, 5024], 'not': [2241, 2525, 5032], 'been': [2242, 5033], 'explored': [2243, 5034], '(22.Tremblay': [2244, 5035], 'L.O.': [2245, 5036], 'Nagy': [2246, 5037], 'Kovács': [2247, 5038], 'E.': [2248, 2250, 2260, 2884, 5039, 5041, 5051], 'Daniels': [2249, 5040], 'Marcinkiewicz': [2259, 5050], 'Seidah': [2261, 5052], 'N.G.': [2262, 5053], 'Herscovics': [2265, 5056], '2558-2566Abstract': [2272, 5063], '(20)': [2280, 5071], '23.Akama': [2283, 5074], 'Sugihara': [2287, 5078], 'Narisawa': [2289, 5080], 'Ohyama': [2291, 5082], "O'Brien": [2295, 5086], 'D.A.': [2296, 5087], 'Millan': [2299, 5090], '295:': [2305, 5096], '124-127Crossref': [2306, 5097], '(124)': [2309, 5100], 'all': [2321, 5112], 'five': [2322, 5113], 'optimal': [2334, 2994, 3091, 5125], 'N-glycans.': [2338, 2556, 5129], 'contrast,': [2340, 2513, 5131], 'negative': [2346, 2875, 5137], 'Mgat1': [2349, 2690, 2989, 3049, 5140], 'presumably': [2353, 5144], 'Mgat4': [2360, 2983, 5151], 'branching.': [2366, 2475, 2511, 2998, 5157], 'Our': [2367, 5158], 'subsequently,': [2391, 5182], 'CTLA-4.DISCUSSIONGlcNAc': [2395], 'such': [2404, 3103], 'CD45,': [2407], 'titrates': [2410], 'galectins,': [2413], 'susceptibility': [2425], 'up-regulates': [2430], 'MGAT5': [2431, 2476, 2533, 3012], 'surface.': [2452], 'find': [2455], 'strongly': [2479], 'genes.': [2491], 'Limiting': [2492], 'confirms': [2502], 'do': [2524], 'correlate': [2526], 'MGAT5/MI/MII': [2528], 'being': [2530], 'when': [2532, 3097], 'maximally': [2536], 'increased.': [2537], 'MAGT1,': [2538], 'MAGT2,': [2539], 'MAGT5': [2541], 'act': [2542], 'sequentially,': [2543], 'utilize': [2544], 'substrate,': [2547], 'absolutely': [2550], 'biosynthesis': [2553], 'However,': [2557], '200-': [2562], '20-fold': [2564], 'unequal': [2572], 'competition': [2573], 'Indeed,': [2608], 'overexpression': [2609], 'transferases': [2623], 'We': [2652], 'conclude': [2653], 'positive': [2655], 'regulation': [2656, 2966, 3092], 'inhibition': [2670], 'require': [2673], 'coordinated': [2674, 3074], 'up-regulation': [2675, 2771, 2792, 2907], 'MI,': [2677], 'MII,': [2678], 'biosynthesis,': [2684], 'coupled': [2685], 'limited': [2687, 3053], 'changes/suppression': [2688], 'Mgat2.MAN2A1-deficient': [2692], 'C57BL/6': [2697], 'change': [2704], 'supplies': [2711], 'sufficient': [2712], 'compensate': [2716], 'Whether': [2751], 'also': [2754], 'true': [2755], 'activated': [2757, 2799, 2830, 2836, 2926], 'requires': [2760], 'further': [2761], 'investigation;': [2762], 'however,': [2763], 'it': [2764], 'consistent': [2766, 3033], 'our': [2768, 3070], 'conclusion': [2769], 'total': [2773], 'activity,': [2775], 'mRNA,': [2783], 'physiologically': [2786], 'relevant': [2787, 2822], 'change.': [2788], 'Similarly,': [2789], 'experimentally': [2790], 'unlikely': [2803], 'be': [2805], 'biologically': [2806], 'significant;': [2807], 'rather,': [2808], 'distributed': [2812], 'over': [2813], 'likely': [2820], 'cells.Enhanced': [2832], '(35.Waterhouse': [2879], 'Penninger': [2881], 'Timms': [2883], 'Wakeham': [2885], 'Shahinian': [2887], 'K.P.': [2890], 'Thompson': [2891], 'C.B.': [2892], 'Griesser': [2893], 'Mak': [2895], 'T.W.': [2896], '1995;': [2898, 3141], '270:': [2899], '985-988Crossref': [2900], '(2354)': [2903], 'Coordinated': [2906], 'MAN1C1,': [2912], 'MAN2A1,': [2913], 'suggests': [2921], 'common': [2923], 'transcriptional': [2924], 'regulator(s)': [2925], 'phosphatidylinositol': [2929, 3085], '3-kinase/ERK': [2930, 3086], 'pathway.': [2931], 'Defining': [2932], 'mechanism': [2935], 'co-regulation': [2938], 'should': [2939], 'provide': [2940], 'new': [2941], 'regulators': [2943], 'expand': [2948], 'hexosamine/Golgi': [2950], 'network': [2952, 2960], 'regulating': [2953], 'retention.': [2956], 'Genetic': [2957], 'variations': [2958], 'prime': [2963], 'candidates': [2964], 'human': [2968], 'autoimmunity.Increasing': [2969], 'necessary': [2992, 3089], 'simple': [3003], 'one': [3008], 'exons,': [3009], '16': [3014], 'exons': [3015], 'long': [3017], 'intervening': [3018], 'introns.': [3019], 'It': [3020], 'tempting': [3022], 'speculate': [3024], 'differences': [3027], 'evolved': [3028], 'permit': [3030], 'continuous': [3031], 'minimum': [3039], 'mono-': [3044], 'biantennary': [3046], 'Mgat2)': [3051], 'tightly': [3055], 'Mgat5.': [3064], 'As': [3065], 'disturbed,': [3098], 'may': [3099], 'lead': [3100], 'diseases': [3102], 'cancer,': [3106], '2': [3109], 'diabetes': [3110], '36.Demetriou': [3128], 'Coppolino': [3132], 'Dedhar': [3134], 'Cell': [3139], '130:': [3142], '383-392Crossref': [3143], '(250)': [3146], '37.Granovsky': [3149], 'Fata': [3151], 'W.J.': [3156], 'Khokha': [3157], 'Med.': [3162], '2000;': [3163], '6:': [3164], '306-312Crossref': [3165], '(461)': [3168], '38.Ohtsubo': [3171], 'Takamatsu': [3173], 'Minowa': [3175], 'M.T.': [3176], 'Yoshida': [3177], 'Takeuchi': [3179], '2005;': [3184], '123:': [3185], '1307-1321Abstract': [3186], '(336)': [3194], 'CTLA-4.': [5186]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086687391', 'counts_by_year': [{'year': 2024, 'cited_by_count': 7}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 4}, {'year': 2021, 'cited_by_count': 2}, {'year': 2020, 'cited_by_count': 9}, {'year': 2019, 'cited_by_count': 2}, {'year': 2018, 'cited_by_count': 3}, {'year': 2017, 'cited_by_count': 4}, {'year': 2016, 'cited_by_count': 3}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 4}, {'year': 2013, 'cited_by_count': 4}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2024-12-26T04:41:20.511364', 'created_date': '2016-06-24'}