Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2086632167', 'doi': 'https://doi.org/10.1038/520609a', 'title': 'Personalized medicine: Time for one-person trials', 'display_name': 'Personalized medicine: Time for one-person trials', 'publication_year': 2015, 'publication_date': '2015-04-01', 'ids': {'openalex': 'https://openalex.org/W2086632167', 'doi': 'https://doi.org/10.1038/520609a', 'mag': '2086632167', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/25925459'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/520609a', 'pdf_url': 'https://www.nature.com/articles/520609a.pdf', 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'bronze', 'oa_url': 'https://www.nature.com/articles/520609a.pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5077225971', 'display_name': 'Nicholas J. Schork', 'orcid': 'https://orcid.org/0000-0003-0920-5013'}, 'institutions': [{'id': 'https://openalex.org/I36258959', 'display_name': 'University of California, San Diego', 'ror': 'https://ror.org/0168r3w48', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I36258959']}], 'countries': ['US'], 'is_corresponding': True, 'raw_author_name': 'Nicholas J. Schork', 'raw_affiliation_strings': ['J. Craig Venter Institute in La Jolla, California, USA. He is also professor at the University of California, San Diego, and at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, USA.'], 'affiliations': [{'raw_affiliation_string': 'J. Craig Venter Institute in La Jolla, California, USA. He is also professor at the University of California, San Diego, and at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona, USA.', 'institution_ids': ['https://openalex.org/I36258959']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': ['https://openalex.org/A5077225971'], 'corresponding_institution_ids': ['https://openalex.org/I36258959'], 'apc_list': {'value': 9750, 'currency': 'EUR', 'value_usd': 11690, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 85.813, 'has_fulltext': True, 'fulltext_origin': 'pdf', 'cited_by_count': 1079, 'citation_normalized_percentile': {'value': 0.999825, 'is_in_top_1_percent': True, 'is_in_top_10_percent': True}, 'cited_by_percentile_year': {'min': 99, 'max': 100}, 'biblio': {'volume': '520', 'issue': '7549', 'first_page': '609', 'last_page': '611'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11235', 'display_name': 'Statistical Methods in Clinical Trials', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2613', 'display_name': 'Statistics and Probability'}, 'field': {'id': 'https://openalex.org/fields/26', 'display_name': 'Mathematics'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11235', 'display_name': 'Statistical Methods in Clinical Trials', 'score': 0.9971, 'subfield': {'id': 'https://openalex.org/subfields/2613', 'display_name': 'Statistics and Probability'}, 'field': {'id': 'https://openalex.org/fields/26', 'display_name': 'Mathematics'}, 'domain': {'id': 'https://openalex.org/domains/3', 'display_name': 'Physical Sciences'}}, {'id': 'https://openalex.org/T10375', 'display_name': 'Pharmacogenetics and Drug Metabolism', 'score': 0.9843, 'subfield': {'id': 'https://openalex.org/subfields/3004', 'display_name': 'Pharmacology'}, 'field': {'id': 'https://openalex.org/fields/30', 'display_name': 'Pharmacology, Toxicology and Pharmaceutics'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10804', 'display_name': 'Health Systems, Economic Evaluations, Quality of Life', 'score': 0.9801, 'subfield': {'id': 'https://openalex.org/subfields/2002', 'display_name': 'Economics and Econometrics'}, 'field': {'id': 'https://openalex.org/fields/20', 'display_name': 'Economics, Econometrics and Finance'}, 'domain': {'id': 'https://openalex.org/domains/2', 'display_name': 'Social Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/personalized-medicine', 'display_name': 'Personalized Medicine', 'score': 0.5386839}], 'concepts': [{'id': 'https://openalex.org/C32220436', 'wikidata': 'https://www.wikidata.org/wiki/Q2072214', 'display_name': 'Personalized medicine', 'level': 2, 'score': 0.5386839}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.3751642}, {'id': 'https://openalex.org/C41008148', 'wikidata': 'https://www.wikidata.org/wiki/Q21198', 'display_name': 'Computer science', 'level': 0, 'score': 0.35033998}, {'id': 'https://openalex.org/C70721500', 'wikidata': 'https://www.wikidata.org/wiki/Q177005', 'display_name': 'Computational biology', 'level': 1, 'score': 0.3212853}, {'id': 'https://openalex.org/C60644358', 'wikidata': 'https://www.wikidata.org/wiki/Q128570', 'display_name': 'Bioinformatics', 'level': 1, 'score': 0.26304036}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.2086407}], 'mesh': [{'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': 'Q000639', 'qualifier_name': 'trends', 'is_major_topic': True}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D057285', 'descriptor_name': 'Precision Medicine', 'qualifier_ui': 'Q000639', 'qualifier_name': 'trends', 'is_major_topic': True}, {'descriptor_ui': 'D057285', 'descriptor_name': 'Precision Medicine', 'qualifier_ui': 'Q000379', 'qualifier_name': 'methods', 'is_major_topic': True}, {'descriptor_ui': 'D012107', 'descriptor_name': 'Research Design', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D061067', 'descriptor_name': 'Antibodies, Monoclonal, Humanized', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001549', 'descriptor_name': 'Benzamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D001549', 'descriptor_name': 'Benzamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015415', 'descriptor_name': 'Biomarkers', 'qualifier_ui': 'Q000032', 'qualifier_name': 'analysis', 'is_major_topic': False}, {'descriptor_ui': 'D000068818', 'descriptor_name': 'Cetuximab', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002986', 'descriptor_name': 'Clinical Trials as Topic', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000068877', 'descriptor_name': 'Imatinib Mesylate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010597', 'descriptor_name': 'Pharmacogenetics', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010597', 'descriptor_name': 'Pharmacogenetics', 'qualifier_ui': 'Q000639', 'qualifier_name': 'trends', 'is_major_topic': False}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010879', 'descriptor_name': 'Piperazines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D057285', 'descriptor_name': 'Precision Medicine', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011743', 'descriptor_name': 'Pyrimidines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D011743', 'descriptor_name': 'Pyrimidines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018401', 'descriptor_name': 'Sample Size', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013449', 'descriptor_name': 'Sulfonamides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D000077484', 'descriptor_name': 'Vemurafenib', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/520609a', 'pdf_url': 'https://www.nature.com/articles/520609a.pdf', 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/25925459', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1038/520609a', 'pdf_url': 'https://www.nature.com/articles/520609a.pdf', 'source': {'id': 'https://openalex.org/S137773608', 'display_name': 'Nature', 'issn_l': '0028-0836', 'issn': ['0028-0836', '1476-4687'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319908', 'host_organization_name': 'Nature Portfolio', 'host_organization_lineage': ['https://openalex.org/P4310319908', 'https://openalex.org/P4310319965'], 'host_organization_lineage_names': ['Nature Portfolio', 'Springer Nature'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 8, 'referenced_works': ['https://openalex.org/W1970765841', 'https://openalex.org/W2008180012', 'https://openalex.org/W2051576298', 'https://openalex.org/W2079859830', 'https://openalex.org/W2085183224', 'https://openalex.org/W2099745794', 'https://openalex.org/W2155311724', 'https://openalex.org/W2312804644'], 'related_works': ['https://openalex.org/W4317499868', 'https://openalex.org/W3013945467', 'https://openalex.org/W3001515824', 'https://openalex.org/W2997019322', 'https://openalex.org/W2899084033', 'https://openalex.org/W2748952813', 'https://openalex.org/W2343628501', 'https://openalex.org/W2132914709', 'https://openalex.org/W1987323012', 'https://openalex.org/W1904334718'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086632167', 'counts_by_year': [{'year': 2024, 'cited_by_count': 75}, {'year': 2023, 'cited_by_count': 77}, {'year': 2022, 'cited_by_count': 146}, {'year': 2021, 'cited_by_count': 106}, {'year': 2020, 'cited_by_count': 138}, {'year': 2019, 'cited_by_count': 144}, {'year': 2018, 'cited_by_count': 145}, {'year': 2017, 'cited_by_count': 114}, {'year': 2016, 'cited_by_count': 89}, {'year': 2015, 'cited_by_count': 33}], 'updated_date': '2024-12-28T18:26:53.918859', 'created_date': '2016-06-24'}