Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2086574524', 'doi': 'https://doi.org/10.1016/s0955-0674(97)80080-4', 'title': 'The metaphase-to-anaphase transition: avoiding a mid-life crisis', 'display_name': 'The metaphase-to-anaphase transition: avoiding a mid-life crisis', 'publication_year': 1997, 'publication_date': '1997-12-01', 'ids': {'openalex': 'https://openalex.org/W2086574524', 'doi': 'https://doi.org/10.1016/s0955-0674(97)80080-4', 'mag': '2086574524', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/9425344'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0955-0674(97)80080-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S103771297', 'display_name': 'Current Opinion in Cell Biology', 'issn_l': '0955-0674', 'issn': ['0955-0674', '1879-0410'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'review', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5019022702', 'display_name': 'Orna Cohen‐Fix', 'orcid': 'https://orcid.org/0000-0001-5682-1287'}, 'institutions': [{'id': 'https://openalex.org/I196817621', 'display_name': 'Carnegie Institution for Science', 'ror': 'https://ror.org/04jr01610', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I196817621']}, {'id': 'https://openalex.org/I1344073410', 'display_name': 'Howard Hughes Medical Institute', 'ror': 'https://ror.org/006w34k90', 'country_code': 'US', 'type': 'nonprofit', 'lineage': ['https://openalex.org/I1344073410']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'O Cohen-Fix', 'raw_affiliation_strings': ['Howard Hughes Medical Institute, Carnegie Institution of Washington, Baltimore, MD 21210, USA. [email protected]'], 'affiliations': [{'raw_affiliation_string': 'Howard Hughes Medical Institute, Carnegie Institution of Washington, Baltimore, MD 21210, USA. [email protected]', 'institution_ids': ['https://openalex.org/I196817621', 'https://openalex.org/I1344073410']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5040167004', 'display_name': 'Douglas Koshland', 'orcid': 'https://orcid.org/0000-0003-3742-6294'}, 'institutions': [], 'countries': [], 'is_corresponding': False, 'raw_author_name': 'D Koshland', 'raw_affiliation_strings': [], 'affiliations': []}], 'countries_distinct_count': 1, 'institutions_distinct_count': 2, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 4530, 'currency': 'USD', 'value_usd': 4530, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 1.182, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 47, 'citation_normalized_percentile': {'value': 0.334755, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 91, 'max': 92}, 'biblio': {'volume': '9', 'issue': '6', 'first_page': '800', 'last_page': '806'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10492', 'display_name': 'Regulation and Function of Microtubules in Cell Division', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10379', 'display_name': 'Cell Mechanics and Extracellular Matrix Interactions', 'score': 0.9965, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12065', 'display_name': 'Role of Hippo Signaling Pathway in Mechanotransduction', 'score': 0.996, 'subfield': {'id': 'https://openalex.org/subfields/1307', 'display_name': 'Cell Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/anaphase-promoting-complex', 'display_name': 'Anaphase-promoting complex', 'score': 0.6347914}, {'id': 'https://openalex.org/keywords/securin', 'display_name': 'Securin', 'score': 0.5067366}, {'id': 'https://openalex.org/keywords/regulations', 'display_name': 'Regulations', 'score': 0.479986}], 'concepts': [{'id': 'https://openalex.org/C53420372', 'wikidata': 'https://www.wikidata.org/wiki/Q22299157', 'display_name': 'Anaphase', 'level': 4, 'score': 0.9595594}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.76728344}, {'id': 'https://openalex.org/C70278784', 'wikidata': 'https://www.wikidata.org/wiki/Q574427', 'display_name': 'Metaphase', 'level': 4, 'score': 0.72575796}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.69988275}, {'id': 'https://openalex.org/C107888121', 'wikidata': 'https://www.wikidata.org/wiki/Q418432', 'display_name': 'Anaphase-promoting complex', 'level': 5, 'score': 0.6347914}, {'id': 'https://openalex.org/C93304396', 'wikidata': 'https://www.wikidata.org/wiki/Q14763008', 'display_name': 'Mitosis', 'level': 2, 'score': 0.5900221}, {'id': 'https://openalex.org/C194232998', 'wikidata': 'https://www.wikidata.org/wiki/Q1606712', 'display_name': 'Transition (genetics)', 'level': 3, 'score': 0.5493736}, {'id': 'https://openalex.org/C63378162', 'wikidata': 'https://www.wikidata.org/wiki/Q6740686', 'display_name': 'Securin', 'level': 5, 'score': 0.5067366}, {'id': 'https://openalex.org/C54355233', 'wikidata': 'https://www.wikidata.org/wiki/Q7162', 'display_name': 'Genetics', 'level': 1, 'score': 0.2773669}, {'id': 'https://openalex.org/C29537977', 'wikidata': 'https://www.wikidata.org/wiki/Q188941', 'display_name': 'Cell cycle', 'level': 3, 'score': 0.13941157}, {'id': 'https://openalex.org/C30481170', 'wikidata': 'https://www.wikidata.org/wiki/Q37748', 'display_name': 'Chromosome', 'level': 3, 'score': 0.083319575}, {'id': 'https://openalex.org/C1491633281', 'wikidata': 'https://www.wikidata.org/wiki/Q7868', 'display_name': 'Cell', 'level': 2, 'score': 0.054345787}, {'id': 'https://openalex.org/C104317684', 'wikidata': 'https://www.wikidata.org/wiki/Q7187', 'display_name': 'Gene', 'level': 2, 'score': 0.0}], 'mesh': [{'descriptor_ui': 'D000705', 'descriptor_name': 'Anaphase', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D008677', 'descriptor_name': 'Metaphase', 'qualifier_ui': 'Q000502', 'qualifier_name': 'physiology', 'is_major_topic': True}, {'descriptor_ui': 'D043743', 'descriptor_name': 'Ubiquitin-Protein Ligase Complexes', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000705', 'descriptor_name': 'Anaphase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D064173', 'descriptor_name': 'Anaphase-Promoting Complex-Cyclosome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016213', 'descriptor_name': 'Cyclins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D016213', 'descriptor_name': 'Cyclins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004789', 'descriptor_name': 'Enzyme Activation', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008025', 'descriptor_name': 'Ligases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D008025', 'descriptor_name': 'Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008677', 'descriptor_name': 'Metaphase', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008954', 'descriptor_name': 'Models, Biological', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000166', 'qualifier_name': 'cytology', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D012441', 'descriptor_name': 'Saccharomyces cerevisiae', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013379', 'descriptor_name': 'Substrate Specificity', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D044767', 'descriptor_name': 'Ubiquitin-Protein Ligases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1016/s0955-0674(97)80080-4', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S103771297', 'display_name': 'Current Opinion in Cell Biology', 'issn_l': '0955-0674', 'issn': ['0955-0674', '1879-0410'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/9425344', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 61, 'referenced_works': ['https://openalex.org/W1209714687', 'https://openalex.org/W1508414663', 'https://openalex.org/W1863775794', 'https://openalex.org/W1901153366', 'https://openalex.org/W1917160910', 'https://openalex.org/W1934183749', 'https://openalex.org/W1938207098', 'https://openalex.org/W1973046803', 'https://openalex.org/W1973916918', 'https://openalex.org/W1976641875', 'https://openalex.org/W1981772689', 'https://openalex.org/W1982515699', 'https://openalex.org/W1991101546', 'https://openalex.org/W1991471131', 'https://openalex.org/W1993935814', 'https://openalex.org/W1994523623', 'https://openalex.org/W1995653496', 'https://openalex.org/W2004784929', 'https://openalex.org/W2005717642', 'https://openalex.org/W2007853809', 'https://openalex.org/W2015754578', 'https://openalex.org/W2016059994', 'https://openalex.org/W2016274030', 'https://openalex.org/W2019068828', 'https://openalex.org/W2027401480', 'https://openalex.org/W2033950216', 'https://openalex.org/W2035759917', 'https://openalex.org/W2036686552', 'https://openalex.org/W2039839254', 'https://openalex.org/W2047524281', 'https://openalex.org/W2048735610', 'https://openalex.org/W2059665827', 'https://openalex.org/W2059859203', 'https://openalex.org/W2063759666', 'https://openalex.org/W2063856790', 'https://openalex.org/W2068449035', 'https://openalex.org/W2069810835', 'https://openalex.org/W2070963888', 'https://openalex.org/W2073501183', 'https://openalex.org/W2074720031', 'https://openalex.org/W2078358000', 'https://openalex.org/W2084223205', 'https://openalex.org/W2084343743', 'https://openalex.org/W2085962516', 'https://openalex.org/W2088357331', 'https://openalex.org/W2096864462', 'https://openalex.org/W2106431538', 'https://openalex.org/W2106869142', 'https://openalex.org/W2124664382', 'https://openalex.org/W2126683450', 'https://openalex.org/W2129153399', 'https://openalex.org/W2136644864', 'https://openalex.org/W2139048284', 'https://openalex.org/W2142823539', 'https://openalex.org/W2146084258', 'https://openalex.org/W2152921746', 'https://openalex.org/W2160425990', 'https://openalex.org/W2188884929', 'https://openalex.org/W2412056115', 'https://openalex.org/W243911327', 'https://openalex.org/W307602372'], 'related_works': ['https://openalex.org/W4225407026', 'https://openalex.org/W2160290453', 'https://openalex.org/W2147819413', 'https://openalex.org/W2134416952', 'https://openalex.org/W2106088231', 'https://openalex.org/W2024065607', 'https://openalex.org/W1997876679', 'https://openalex.org/W1974425134', 'https://openalex.org/W1964422654', 'https://openalex.org/W1963505391'], 'abstract_inverted_index': {'The': [0, 19], 'metaphase-to-anaphase': [1], 'transition': [2], 'is': [3, 9], 'a': [4], 'highly': [5], 'regulated': [6], 'process,': [7], 'which': [8], 'governed': [10], 'by': [11], 'the': [12, 15, 22, 44], 'activity': [13], 'of': [14, 24, 46], 'anaphase-promoting': [16], 'complex': [17], '(APC).': [18], 'APC': [20, 47], 'promotes': [21], 'degradation': [23], 'several': [25], 'proteins,': [26], 'including': [27], 'mitotic': [28], 'cyclins': [29], 'and': [30, 49], 'newly': [31], 'identified': [32], 'anaphase': [33], 'inhibitors.': [34], 'Several': [35], 'discoveries': [36], 'made': [37], 'this': [38], 'year': [39], 'shed': [40], 'invaluable': [41], 'light': [42], 'on': [43], 'regulation': [45], 'activation': [48], 'its': [50], 'substrate': [51], 'specificity.': [52]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086574524', 'counts_by_year': [{'year': 2020, 'cited_by_count': 1}, {'year': 2015, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 1}, {'year': 2012, 'cited_by_count': 1}], 'updated_date': '2024-08-15T12:58:26.598618', 'created_date': '2016-06-24'}