Publication Information

{'id': 'https://openalex.org/W2086507786', 'doi': 'https://doi.org/10.1074/jbc.m100190200', 'title': 'Kainate Receptor Activation Induces Mixed Lineage Kinase-mediated Cellular Signaling Cascades via Post-synaptic Density Protein 95', 'display_name': 'Kainate Receptor Activation Induces Mixed Lineage Kinase-mediated Cellular Signaling Cascades via Post-synaptic Density Protein 95', 'publication_year': 2001, 'publication_date': '2001-04-01', 'ids': {'openalex': 'https://openalex.org/W2086507786', 'doi': 'https://doi.org/10.1074/jbc.m100190200', 'mag': '2086507786', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/11152698'}, 'language': 'en', 'primary_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m100190200', 'pdf_url': 'http://www.jbc.org/article/S0021925819345909/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': True, 'oa_status': 'hybrid', 'oa_url': 'http://www.jbc.org/article/S0021925819345909/pdf', 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5056800538', 'display_name': 'Anneli Savinainen', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I12912129', 'display_name': 'Northeastern University', 'ror': 'https://ror.org/04t5xt781', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I12912129']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Anneli Savinainen', 'raw_affiliation_strings': ['From the Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, the'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, the', 'institution_ids': ['https://openalex.org/I12912129']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5108220720', 'display_name': 'Elizabeth P. Garcia', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I196272386', 'display_name': 'Providence College', 'ror': 'https://ror.org/00rxpqe74', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I196272386']}, {'id': 'https://openalex.org/I27804330', 'display_name': 'Brown University', 'ror': 'https://ror.org/05gq02987', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I27804330']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Elizabeth P. Garcia', 'raw_affiliation_strings': ['Department Of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912 and the'], 'affiliations': [{'raw_affiliation_string': 'Department Of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912 and the', 'institution_ids': ['https://openalex.org/I196272386', 'https://openalex.org/I27804330']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5020188732', 'display_name': 'Donna S. Dorow', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2800555584', 'display_name': 'Peter MacCallum Cancer Centre', 'ror': 'https://ror.org/02a8bt934', 'country_code': 'AU', 'type': 'healthcare', 'lineage': ['https://openalex.org/I2800555584']}], 'countries': ['AU'], 'is_corresponding': False, 'raw_author_name': 'Donna Dorow', 'raw_affiliation_strings': ['Trecowthick Research Center, Peter MacCallum Cancer Institute, Melbourne, Victoria 3000, Australia'], 'affiliations': [{'raw_affiliation_string': 'Trecowthick Research Center, Peter MacCallum Cancer Institute, Melbourne, Victoria 3000, Australia', 'institution_ids': ['https://openalex.org/I2800555584']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5013866493', 'display_name': 'J. Marshall', 'orcid': 'https://orcid.org/0000-0002-6481-8413'}, 'institutions': [{'id': 'https://openalex.org/I196272386', 'display_name': 'Providence College', 'ror': 'https://ror.org/00rxpqe74', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I196272386']}, {'id': 'https://openalex.org/I27804330', 'display_name': 'Brown University', 'ror': 'https://ror.org/05gq02987', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I27804330']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'John Marshall', 'raw_affiliation_strings': ['Department Of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912 and the'], 'affiliations': [{'raw_affiliation_string': 'Department Of Molecular Pharmacology, Physiology, and Biotechnology, Brown University, Providence, Rhode Island 02912 and the', 'institution_ids': ['https://openalex.org/I196272386', 'https://openalex.org/I27804330']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5047379990', 'display_name': 'Ya Fang Liu', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I12912129', 'display_name': 'Northeastern University', 'ror': 'https://ror.org/04t5xt781', 'country_code': 'US', 'type': 'education', 'lineage': ['https://openalex.org/I12912129']}], 'countries': ['US'], 'is_corresponding': False, 'raw_author_name': 'Ya Fang Liu', 'raw_affiliation_strings': ['From the Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, the'], 'affiliations': [{'raw_affiliation_string': 'From the Department of Pharmaceutical Sciences, Northeastern University, Boston, Massachusetts 02115, the', 'institution_ids': ['https://openalex.org/I12912129']}]}], 'institution_assertions': [], 'countries_distinct_count': 2, 'institutions_distinct_count': 4, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'apc_paid': {'value': 2500, 'currency': 'USD', 'value_usd': 2500, 'provenance': 'doaj'}, 'fwci': 3.249, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 110, 'citation_normalized_percentile': {'value': 0.856469, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 96, 'max': 97}, 'biblio': {'volume': '276', 'issue': '14', 'first_page': '11382', 'last_page': '11386'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T10077', 'display_name': 'Neuroscience and Neuropharmacology Research', 'score': 0.9999, 'subfield': {'id': 'https://openalex.org/subfields/2804', 'display_name': 'Cellular and Molecular Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T10169', 'display_name': 'Protein Kinase Regulation and GTPase Signaling', 'score': 0.9953, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T12610', 'display_name': 'RNA regulation and disease', 'score': 0.9928, 'subfield': {'id': 'https://openalex.org/subfields/1312', 'display_name': 'Molecular Biology'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/kainate-receptor', 'display_name': 'Kainate receptor', 'score': 0.6717682}], 'concepts': [{'id': 'https://openalex.org/C189184402', 'wikidata': 'https://www.wikidata.org/wiki/Q3454536', 'display_name': 'Kainate receptor', 'level': 5, 'score': 0.6717682}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.5616262}, {'id': 'https://openalex.org/C185592680', 'wikidata': 'https://www.wikidata.org/wiki/Q2329', 'display_name': 'Chemistry', 'level': 0, 'score': 0.53295904}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.41054326}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.38530013}, {'id': 'https://openalex.org/C169760540', 'wikidata': 'https://www.wikidata.org/wiki/Q207011', 'display_name': 'Neuroscience', 'level': 1, 'score': 0.3357557}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.33314103}, {'id': 'https://openalex.org/C61174792', 'wikidata': 'https://www.wikidata.org/wiki/Q420510', 'display_name': 'Glutamate receptor', 'level': 3, 'score': 0.2710067}, {'id': 'https://openalex.org/C55493867', 'wikidata': 'https://www.wikidata.org/wiki/Q7094', 'display_name': 'Biochemistry', 'level': 1, 'score': 0.2156561}, {'id': 'https://openalex.org/C160268369', 'wikidata': 'https://www.wikidata.org/wiki/Q295251', 'display_name': 'AMPA receptor', 'level': 4, 'score': 0.19695407}], 'mesh': [{'descriptor_ui': 'D048031', 'descriptor_name': 'JNK Mitogen-Activated Protein Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D020935', 'descriptor_name': 'MAP Kinase Signaling System', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D018092', 'descriptor_name': 'Receptors, Kainic Acid', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000076122', 'descriptor_name': 'Disks Large Homolog 4 Protein', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D047908', 'descriptor_name': 'Intracellular Signaling Peptides and Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D048670', 'descriptor_name': 'MAP Kinase Kinase 4', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020930', 'descriptor_name': 'MAP Kinase Kinase Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020930', 'descriptor_name': 'MAP Kinase Kinase Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008565', 'descriptor_name': 'Membrane Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000097767', 'descriptor_name': 'Mitogen-Activated Protein Kinase Kinase Kinase 11', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D020929', 'descriptor_name': 'Mitogen-Activated Protein Kinase Kinases', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D020929', 'descriptor_name': 'Mitogen-Activated Protein Kinase Kinases', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009419', 'descriptor_name': 'Nerve Tissue Proteins', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009474', 'descriptor_name': 'Neurons', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018092', 'descriptor_name': 'Receptors, Kainic Acid', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m100190200', 'pdf_url': 'http://www.jbc.org/article/S0021925819345909/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/11152698', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': {'is_oa': True, 'landing_page_url': 'https://doi.org/10.1074/jbc.m100190200', 'pdf_url': 'http://www.jbc.org/article/S0021925819345909/pdf', 'source': {'id': 'https://openalex.org/S140251998', 'display_name': 'Journal of Biological Chemistry', 'issn_l': '0021-9258', 'issn': ['0021-9258', '1067-8816', '1083-351X'], 'is_oa': True, 'is_in_doaj': True, 'is_core': True, 'host_organization': 'https://openalex.org/P4310320990', 'host_organization_name': 'Elsevier BV', 'host_organization_lineage': ['https://openalex.org/P4310320990'], 'host_organization_lineage_names': ['Elsevier BV'], 'type': 'journal'}, 'license': 'cc-by', 'license_id': 'https://openalex.org/licenses/cc-by', 'version': 'publishedVersion', 'is_accepted': True, 'is_published': True}, 'sustainable_development_goals': [], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 27, 'referenced_works': ['https://openalex.org/W1530284699', 'https://openalex.org/W1612819372', 'https://openalex.org/W1624178692', 'https://openalex.org/W1965747240', 'https://openalex.org/W1976385326', 'https://openalex.org/W1977394169', 'https://openalex.org/W1987414255', 'https://openalex.org/W1993385893', 'https://openalex.org/W1998487776', 'https://openalex.org/W2002763309', 'https://openalex.org/W2005569599', 'https://openalex.org/W2024431713', 'https://openalex.org/W2026793631', 'https://openalex.org/W2026951979', 'https://openalex.org/W2029242493', 'https://openalex.org/W2033717303', 'https://openalex.org/W2043873927', 'https://openalex.org/W2059124316', 'https://openalex.org/W2073730363', 'https://openalex.org/W2078078069', 'https://openalex.org/W2093573816', 'https://openalex.org/W2095123707', 'https://openalex.org/W2100353665', 'https://openalex.org/W2114096006', 'https://openalex.org/W2129108032', 'https://openalex.org/W2158584175', 'https://openalex.org/W2159030157'], 'related_works': ['https://openalex.org/W4238295633', 'https://openalex.org/W4231757633', 'https://openalex.org/W290006895', 'https://openalex.org/W2070359942', 'https://openalex.org/W2038575827', 'https://openalex.org/W2018845721', 'https://openalex.org/W2008071500', 'https://openalex.org/W1999076238', 'https://openalex.org/W1992392537', 'https://openalex.org/W174193385'], 'abstract_inverted_index': {'Kainate': [0, 238, 4094], 'receptor': [1, 3, 121, 236, 239, 241, 359, 474, 478, 557, 776, 780, 2683, 2694, 2714, 2725, 3710, 3727, 3859, 4336, 4356], 'glutamate': [2, 240, 477, 626, 1080, 2676], '6': [4, 242, 479], '(GluR6)': [5, 243], 'subunit-deficient': [6, 244], 'and': [7, 23, 44, 74, 126, 133, 145, 154, 169, 184, 191, 197, 213, 229, 245, 261, 282, 312, 364, 371, 383, 392, 407, 422, 429, 435, 451, 467, 538, 568, 571, 668, 735, 778, 783, 874, 884, 993, 998, 1048, 1086, 1121, 1206, 1292, 1312, 1328, 1331, 1337, 1402, 1412, 1494, 1507, 1523, 1565, 1630, 1638, 1641, 1668, 1691, 1740, 1826, 1830, 1973, 2030, 2057, 2118, 2150, 2236, 2307, 2332, 2381, 2494, 2509, 2512, 2521, 2620, 2692, 2740, 2865, 2913, 2950, 3019, 3290, 3307, 3379, 3458, 3467, 3585, 3610, 3617, 3634, 3647, 3662, 3671, 3677, 3695, 3715, 3745, 3758, 3860, 3869, 3882, 4145, 4158, 4313, 4367, 4373, 4391], 'c-Jun': [8, 246, 494], 'N-terminal': [9, 247, 495, 1305], 'kinase': [10, 110, 180, 181, 248, 348, 418, 419, 482, 496, 504, 505, 519, 738, 890, 1105, 1300, 1310, 3786, 3865, 4359], '3': [11, 206, 249, 444, 499, 2751, 2854], '(JNK3)-null': [12, 250], 'mice': [13, 251, 972, 1247, 2514, 3460, 3513, 4160], 'share': [14, 252, 4317], 'similar': [15, 253, 1241, 3505, 4319], 'phenotypes': [16, 254], 'including': [17, 255], 'resistance': [18, 256, 3463], 'to': [19, 103, 119, 234, 257, 341, 357, 472, 625, 768, 770, 870, 957, 963, 1082, 1242, 1320, 1469, 1486, 1498, 1504, 1587, 1597, 1608, 1662, 1824, 1965, 2243, 2245, 2341, 2438, 2450, 2459, 2471, 2477, 2517, 2671, 2696, 2742, 2879, 2887, 3048, 3116, 3142, 3155, 3173, 3282, 3395, 3464, 3711, 3725, 3733, 3743, 3768, 3867, 3921, 3996, 4012, 4230, 4299, 4322, 4329, 4357, 4383], 'kainite-induced': [20, 258], 'epileptic': [21, 259], 'seizures': [22, 260, 2520], 'neuronal': [24, 156, 170, 192, 214, 262, 394, 408, 430, 452, 880, 1049, 1114, 1198, 1207, 1508, 1520, 2234, 2522, 3054, 3104, 3144, 3164, 3195, 3227, 3244, 3262, 3332, 3404, 3465, 3593, 3635, 3675, 3731, 3779, 3923, 3948, 4006, 4300, 4324], 'toxicity': [25, 193, 263, 431, 3105, 3145, 3228, 3245, 3263, 3636, 3732, 3924, 3949], '(Yang,': [26, 264], 'D.': [27, 265, 1445, 1784, 1927, 1984, 4270], 'D.,': [28, 266], 'Kuan,': [29, 267], 'C-Y.,': [30, 268], 'Whitmarsh,': [31, 269], 'A.': [32, 270, 745, 805, 946, 1251, 1351, 1375, 1387, 1419, 1431, 1557, 1574, 2552, 2788, 2812, 2824, 3411, 3447, 3476, 3798, 3822, 3834, 4047, 4071, 4083, 4264, 4277, 4385], 'J.,': [33, 41, 271, 279], 'Rincon,': [34, 272], 'M.,': [35, 273], 'Zheng,': [36, 274], 'T.': [37, 275, 844, 931, 935, 939, 1132, 1155, 1383, 1427, 1758, 1853, 2258, 2395, 2820, 3830, 3957, 3963, 4079], 'S.,': [38, 276], 'Davis,': [39, 277], 'R.': [40, 46, 278, 284, 574, 1052, 1227, 2539, 3076, 3529, 3893, 4204, 4365, 4393], 'Rakis,': [42, 280], 'P.,': [43, 281], 'Flavell,': [45, 283], '(1997)': [47, 285], 'Nature': [48, 79, 286, 317], '389,': [49, 287], '865–869;': [50, 288], 'Mulle,': [51, 289], 'C.,': [52, 65, 290, 303], 'Seiler,': [53, 291], 'A.,': [54, 292], 'Perez-Otano,': [55, 293], 'I.,': [56, 63, 294, 301, 1157], 'Dickinson-Anson,': [57, 295], 'H.,': [58, 68, 296, 306], 'Castillo,': [59, 297], 'P.': [60, 298, 1007, 1128, 1225, 1379, 1423, 2537, 2816, 3443, 3527, 3826, 4075], 'E.,': [61, 299], 'Bureau,': [62, 300], 'Maron,': [64, 302], 'Gage,': [66, 304], 'F.': [67, 77, 305, 315, 907], 'Mann,': [69, 307], 'J.': [70, 308, 842, 850, 1138, 1153, 1160, 1178, 1353, 1356, 1389, 1433, 1447, 1448, 1532, 1756, 1764, 1785, 1851, 1859, 1902, 1929, 1930, 1948, 1986, 1987, 2005, 2256, 2264, 2393, 2401, 2790, 2793, 2826, 3800, 3803, 3836, 3961, 3968, 4049, 4052, 4085, 4241, 4260], 'R.,': [71, 309], 'Bettler,': [72, 310], 'B.,': [73, 311], 'Heinemmann,': [75, 313], 'S.': [76, 314, 543, 836, 937, 945, 1341, 1355, 1750, 1845, 2250, 2387, 2778, 2792, 3788, 3802, 3959, 4037, 4051, 4276, 4368], '(1998)': [78, 316], '392,': [80, 318], '601–605).': [81, 319], 'This': [82, 320, 1237, 1714, 2883, 4326], 'suggests': [83, 321, 1073, 1280, 4309], 'that': [84, 96, 219, 322, 334, 457, 623, 727, 1074, 1109, 1243, 1281, 1317, 1405, 1479, 2227, 2338, 2434, 2467, 2491, 2582, 2666, 2756, 2897, 2910, 3059, 3137, 3234, 3278, 3319, 3371, 3386, 3540, 3557, 3601, 3683, 3721, 3764, 3848, 3941, 3986, 4291, 4310], 'JNK': [85, 104, 167, 189, 211, 227, 323, 342, 405, 427, 449, 465, 1100, 1282, 1410, 1505, 1918, 2511, 2600, 2621, 2638, 2647, 2667, 2702, 2733, 2748, 2764, 2776, 2848, 2870, 2952, 2976, 2995, 3210, 3563, 3583, 3589, 3615, 3632, 3660, 3713, 3756], 'activation': [86, 105, 168, 190, 212, 228, 324, 343, 406, 428, 450, 466, 1044, 1283, 1411, 1506, 2601, 2668, 2672, 2703, 2749, 2757, 2871, 2953, 2977, 2996, 3069, 3253, 3402, 3541, 3564, 3584, 3590, 3611, 3616, 3633, 3661, 3714, 3757, 3856, 3870, 3886, 3917, 4292, 4312], 'may': [87, 325, 1284, 1318, 2286, 2339, 2496, 2884, 2899, 3544, 3687, 4097, 4297, 4316], 'be': [88, 326, 1285, 2287, 2586, 2880, 2885, 3545], 'involved': [89, 327, 1286, 2845, 3259, 3546, 3945], 'in': [90, 130, 149, 225, 328, 368, 387, 463, 525, 559, 616, 620, 796, 1078, 1091, 1106, 1112, 1245, 1287, 1334, 1624, 1686, 1706, 1813, 2048, 2062, 2080, 2130, 2137, 2171, 2175, 2182, 2196, 2233, 2292, 2297, 2304, 2429, 2498, 2602, 2766, 2846, 2852, 2872, 2891, 2905, 2960, 3010, 3068, 3102, 3106, 3122, 3146, 3240, 3246, 3260, 3264, 3269, 3328, 3398, 3406, 3510, 3547, 3619, 3673, 3678, 3717, 3880, 3946, 4015, 4102, 4111, 4152, 4337], 'GluR6-mediated': [91, 226, 329, 464, 1288, 1475, 2583, 2732, 2847, 2994, 3103, 3143, 3261, 3357, 3592, 3659], 'excitotoxicity.': [92, 330, 1289, 1476], 'We': [93, 331, 1477, 2317, 2432, 2464, 2908, 3984, 4362, 4379], 'provide': [94, 332, 3599], 'evidence': [95, 333, 3600], 'post-synaptic': [97, 335, 483, 982], 'density': [98, 336, 484, 983], 'protein': [99, 337, 485, 492, 518, 721, 726, 888, 1680, 1715, 1879], '(PSD-95)': [100, 338], 'links': [101, 339, 4353], 'GluR6': [102, 148, 164, 340, 386, 402, 781, 1631, 2246, 2291, 2301, 2598, 2643, 2759, 2898, 2911, 2934, 2971, 3005, 3015, 3235, 3277, 3314, 3387, 3401, 3581, 3602, 3613, 3672, 3703, 4010, 4225, 4311], 'by': [106, 195, 231, 344, 433, 469, 1117, 1122, 1303, 1805, 2123, 2588, 2625, 2955, 2979, 3072, 3313, 3373, 3470, 3550, 3638, 3761, 3889, 3935, 3951, 4303], 'anchoring': [107, 232, 345, 470], 'mixed': [108, 346, 480, 1298], 'lineage': [109, 347, 481, 1299], '(MLK)': [111, 349], '2': [112, 350], 'or': [113, 178, 351, 416, 627, 682, 793, 960, 1492, 1582, 1736, 2074, 2086, 2101, 2108, 2139, 2165, 2174, 2189, 2202, 2219, 2372, 2425, 2441, 2458, 2479, 2861, 2863, 2935, 3305, 3377, 3627, 3665, 3685], 'MLK3,': [114, 177, 352, 415], 'upstream': [115, 353, 3652], 'activators': [116, 354, 3653], 'of': [117, 124, 143, 147, 159, 163, 173, 199, 355, 362, 381, 385, 397, 401, 411, 437, 533, 612, 774, 791, 966, 978, 989, 1038, 1045, 1195, 1200, 1296, 1407, 1474, 1483, 1490, 1501, 1555, 1561, 1614, 1619, 1666, 1695, 1734, 1832, 1876, 2212, 2326, 2345, 2452, 2482, 2507, 2597, 2630, 2642, 2673, 2682, 2686, 2706, 2720, 2731, 2736, 2758, 2775, 2840, 2857, 2929, 2933, 2937, 2941, 2946, 2964, 2970, 2983, 3004, 3014, 3034, 3042, 3070, 3100, 3150, 3168, 3189, 3199, 3219, 3243, 3254, 3274, 3292, 3301, 3331, 3335, 3349, 3364, 3542, 3559, 3588, 3612, 3623, 3643, 3654, 3698, 3702, 3708, 3723, 3738, 3747, 3751, 3766, 3772, 3778, 3850, 3857, 3863, 3871, 3885, 3887, 3988, 4105, 4108, 4139, 4155, 4223, 4234, 4293, 4334, 4340, 4376], 'JNKs,': [118, 356, 3655], 'the': [120, 140, 160, 235, 358, 378, 398, 473, 521, 526, 671, 771, 789, 797, 885, 976, 986, 1096, 1193, 1297, 1471, 1480, 1487, 1499, 1609, 1653, 1669, 1687, 1692, 1722, 1727, 1814, 2028, 2036, 2049, 2063, 2106, 2176, 2293, 2320, 2324, 2342, 2472, 2589, 2664, 2697, 2743, 2930, 2938, 2947, 2956, 2965, 2980, 3049, 3098, 3117, 3126, 3156, 3166, 3207, 3241, 3298, 3329, 3362, 3365, 3606, 3639, 3699, 3706, 3709, 3726, 3748, 3769, 3851, 3858, 3864, 3872, 3883, 3926, 3936, 3947, 3997, 4023, 4033, 4103, 4153, 4219, 4224, 4331, 4335, 4338, 4377, 4388], 'complex.': [122, 237, 360, 475, 2500], 'Association': [123, 361], 'MLK2': [125, 363, 1291, 1408, 1491, 1550, 1654, 1685, 2073, 2085, 2164, 2205, 2216, 2306, 2331, 2424, 2435, 2860, 3304, 3376, 3626, 3664, 3684], 'MLK3': [127, 365, 1293, 1493, 1568, 1642, 2075, 2166, 2220, 2308, 2333, 2427, 2468, 2862, 2877, 3338, 3628, 3666, 3686, 4389], 'with': [128, 201, 366, 439, 630, 679, 1593, 1616, 1699, 1726, 1894, 2078, 2114, 2148, 2169, 2199, 2231, 2283, 2290, 2314, 2328, 2422, 2612, 2655, 2985, 3180, 3206, 3222, 3351, 3669, 3693, 4022], 'PSD-95': [129, 200, 220, 367, 438, 458, 867, 955, 1039, 1075, 1484, 1629, 1834, 2079, 2134, 2151, 2170, 2179, 2213, 2228, 2240, 2327, 2347, 2439, 2453, 2483, 2942, 2984, 3064, 3283, 3350, 3394, 3670, 3694, 3724, 3739, 3752, 3773, 3876, 4352], 'HN33': [131, 150, 369, 388, 1514, 1581, 1890, 2023, 2172, 2186, 2603, 2767, 2873, 2892, 2906, 3011, 3107, 3147, 3247, 3265, 3399, 3620, 3718, 3914, 4016], 'cells': [132, 151, 370, 389, 1525, 1584, 1697, 1891, 1970, 2024, 2042, 2059, 2082, 2091, 2173, 2235, 2609, 3021, 3035, 3170, 3200, 3676], 'rat': [134, 372, 1518, 1688, 2177, 2191, 2237, 3679], 'brain': [135, 373, 1689, 1738, 2192, 2238, 3680], 'preparations': [136, 374], 'is': [137, 375, 723, 996, 1001, 1076, 1101, 1110, 1239, 1703, 1717, 2167, 2229, 2241, 2281, 2503, 2771, 2924, 3062, 3258, 3578, 3667, 3728, 3774, 3782, 3847, 3944, 4142], 'dependent': [138, 376], 'upon': [139, 377, 2653, 3855], 'SH3': [141, 379, 733, 1306, 1321, 1481, 2343, 2364, 2440, 2473, 2939, 2988, 3354, 3736, 3749, 3770], 'domain': [142, 207, 380, 445, 739, 1482, 2344, 2378, 2443, 2474, 2940, 2989, 3355, 3737, 3750, 3771, 3866], 'PSD-95,': [144, 382, 716, 974, 2094, 2284, 2493], 'expression': [146, 384, 1040, 1406, 2596, 2641, 3003, 3273, 4028], 'activated': [152, 390], 'JNKs': [153, 391, 1339, 2508, 3543, 3604], 'induced': [155, 393, 1116, 3016, 3312, 3469, 3637, 3934, 4302], 'apoptosis.': [157, 395, 1509, 3663], 'Deletion': [158, 396, 3697], 'PSD-95-binding': [161, 399, 2931, 3700], 'site': [162, 400, 2932, 3701], 'reduced': [165, 403, 4144], 'both': [166, 404, 2305, 2510, 3631, 3755], 'toxicity.': [171, 215, 409, 453, 3299, 3333, 3594, 3780], 'Co-expression': [172, 410, 2982, 3300, 3334, 3622], 'dominant': [174, 412, 2858, 3302, 3336, 3374, 3624, 3644], 'negative': [175, 413, 2041, 2098, 2859, 2876, 3303, 3337, 3375, 3625, 3645], 'MLK2,': [176, 414, 1701], 'mitogen-activated': [179, 417, 503, 517], '(MKK)': [182, 420], '4': [183, 421, 3039, 3124, 3186, 3203, 3271, 3316], 'MKK7': [185, 423, 2866, 3308, 3380, 4396], 'also': [186, 208, 424, 446, 717, 868, 2214, 2465, 2991, 3508, 3656], 'significantly': [187, 425, 1210, 2700, 2867, 2992, 3162, 3193, 3309, 3629, 3657, 3704, 3753, 4143], 'attenuated': [188, 426, 1211, 2701, 3194], 'mediated': [194, 432, 2587, 2954, 2978, 3372, 3549, 3760, 3950], 'GluR6,': [196, 434, 570, 1502, 2492, 3762], 'co-expression': [198, 436, 3348, 3642], 'a': [202, 222, 440, 460, 631, 724, 732, 736, 964, 1102, 1197, 1304, 1308, 1313, 1552, 1570, 1678, 2097, 2335, 2499, 2504, 2680, 2690, 2711, 2722, 2728, 2772, 2917, 2986, 3043, 3110, 3237, 3275, 3325, 3340, 3352, 3462, 3690, 3783, 3991, 4231, 4286, 4318, 4354], 'deficient': [203, 441, 3353], 'Src': [204, 442, 497, 886], 'homology': [205, 443, 498, 561], 'inhibited': [209, 447, 2868, 2993, 3310, 3356, 3658], 'GluR6-induced': [210, 448, 2869, 3922, 4005], 'Our': [216, 454, 3845], 'results': [217, 455, 619], 'suggest': [218, 456, 2490, 2755, 2896, 3940], 'plays': [221, 459, 1087, 3236], 'critical': [223, 461, 1077, 3775, 4374], 'role': [224, 462, 1090, 3099, 3239, 3327, 4101, 4333], 'excitotoxicity': [230, 468, 1050, 1124, 2584, 3548, 3881, 4096], 'MLK': [233, 471], 'N-methyl-d-aspartate': [476], '95': [486], '(also': [487], 'known': [488, 718, 2242], 'as': [489, 719, 879, 1682, 1744, 1811, 1921, 1978, 2096], 'SAP-90,': [490], 'synapse-associated': [491, 720], '90)': [493], 'α-amino-3-hydroxy-5-methyl-4-isoxazole': [500], 'proprionate': [501], '6-cyano-7-nitroquinoxaline-2,3-dione': [502], "Huntington's": [506], 'disease': [507], 'GST,': [508], 'glutathioneS-transferase': [509], 'Tdt-mediated': [510], 'dUTP-biotin': [511], 'nick': [512], 'end': [513], 'labeling': [514], 'kainate': [515, 539, 556, 779, 794, 961, 2691, 3560, 4140, 4355], 'acid': [516, 629, 2616, 2659, 3154, 3184, 3294, 3472, 4110], 'Glutamate,': [520], 'major': [522, 1103, 3238], 'excitatory': [523], 'neurotransmitter': [524], 'central': [527, 1097], 'nervous': [528, 1098], 'system,': [529], 'gates': [530], 'three': [531, 729], 'types': [532], 'ionotropic': [534, 2675], 'receptors:': [535], 'NMDA,1': [536], 'AMPA,': [537], '(3Hollman': [540], 'M.': [541, 597, 636, 685, 747, 807, 823, 827, 1005, 1009, 1015, 1058, 1062, 1136, 1176, 1219, 1343, 1345, 2531, 2780, 2782, 3082, 3086, 3521, 3790, 3792, 3899, 3903, 4039, 4041, 4262], 'Heinemann': [542], 'Annu.': [544], 'Rev.': [545], 'Neurosci.': [546], '1994;': [547, 1142, 1166, 4173], '17:': [548, 750, 810, 1391, 1435, 2828, 3838, 4087], '31-108Crossref': [549], 'PubMed': [550, 606, 645, 662, 694, 711, 757, 817, 860, 925, 950, 1032, 1067, 1145, 1187, 1232, 1274, 1367, 1393, 1437, 1459, 1543, 1774, 1796, 1869, 1913, 1941, 1959, 1998, 2016, 2274, 2411, 2544, 2575, 2804, 2830, 3091, 3434, 3453, 3499, 3534, 3572, 3814, 3840, 3908, 3979, 4063, 4089, 4132, 4176, 4213], 'Scopus': [551, 592, 607, 646, 663, 695, 712, 758, 818, 861, 926, 951, 1033, 1068, 1146, 1169, 1188, 1233, 1275, 1368, 1394, 1438, 1460, 1544, 1775, 1797, 1870, 1914, 1942, 1960, 1999, 2017, 2275, 2412, 2545, 2576, 2805, 2831, 3092, 3435, 3454, 3500, 3535, 3573, 3815, 3841, 3909, 3980, 4064, 4090, 4133, 4177, 4214, 4281], '(3638)': [552], 'Google': [553, 594, 609, 648, 665, 697, 714, 760, 820, 863, 928, 953, 1035, 1070, 1148, 1171, 1190, 1235, 1277, 1370, 1396, 1440, 1462, 1546, 1777, 1799, 1872, 1916, 1944, 1962, 2001, 2019, 2277, 2414, 2547, 2578, 2807, 2833, 3094, 3437, 3456, 3502, 3537, 3575, 3817, 3843, 3911, 3982, 4066, 4092, 4135, 4179, 4216, 4283], 'Scholar).': [554, 610, 666, 715, 761, 864, 954, 1036, 1191, 1236, 1397, 1463, 1547, 1800, 1873, 1917, 1963, 2020, 2278, 2415, 3095, 3503, 3844, 3912, 3983, 4093, 4136, 4217, 4284], 'Five': [555], 'subunits': [558, 615], 'two': [560, 2842], 'groups': [562], 'have': [563, 765, 1526, 1838, 3555], 'been': [564, 766, 1527, 1839, 3066, 3878, 4228], 'identified:': [565], 'KA1,': [566], 'KA2,': [567, 669], 'GluR5,': [569, 680], 'GluR7': [572], '(4Chittajallu': [573], 'Braithwaite': [575], 'S.P.': [576], 'Clarke': [577], 'V.R.J.': [578], 'Henley': [579], 'J.M.': [580, 1126, 1347, 2784, 3794, 4043], 'Trends': [581], 'Pharmacol.': [582], 'Sci.': [583, 943, 4209, 4274], '2000;': [584, 603, 642, 691, 1451, 1933, 1990, 3450, 3569, 4253], '20:': [585], '26-35Abstract': [586], 'Full': [587, 589, 752, 754, 812, 814, 855, 857, 920, 922, 1362, 1364, 1454, 1456, 1538, 1540, 1769, 1771, 1791, 1793, 1864, 1866, 1908, 1910, 1936, 1938, 1954, 1956, 1993, 1995, 2011, 2013, 2269, 2271, 2406, 2408, 2799, 2801, 3809, 3811, 3974, 3976, 4058, 4060], 'Text': [588, 590, 753, 755, 813, 815, 856, 858, 921, 923, 1363, 1365, 1455, 1457, 1539, 1541, 1770, 1772, 1792, 1794, 1865, 1867, 1909, 1911, 1937, 1939, 1955, 1957, 1994, 1996, 2012, 2014, 2270, 2272, 2407, 2409, 2800, 2802, 3810, 3812, 3975, 3977, 4059, 4061], 'PDF': [591, 756, 816, 859, 924, 1366, 1458, 1542, 1773, 1795, 1868, 1912, 1940, 1958, 1997, 2015, 2273, 2410, 2803, 3813, 3978, 4062], '(225)': [593, 862, 1776, 1871, 2276, 2413], 'Scholar,': [595, 649, 698, 821, 832, 929, 1149, 1172, 1371, 1441, 1778, 1945, 2002, 2548, 2808, 3818, 4067, 4180, 4256], '5Frerking': [596], 'Nicoll': [598, 637, 686], 'R.A.': [599, 638, 687], 'Curr.': [600, 639, 688], 'Opin.': [601, 640, 689], 'Neurobiol.': [602, 641, 690, 3448], '10:': [604, 643, 692], '342-351Crossref': [605, 644, 693], '(150)': [608, 647, 696], 'Expression': [611, 2629, 3013, 3609], 'individual': [613], 'GluR5–7': [614], 'heterologous': [617], 'systems': [618, 1108], 'homomeric': [621], 'receptors': [622, 795, 962, 980, 1081, 3074, 3561, 3891, 3953, 4141, 4148], 'respond': [624], 'kainic': [628, 1202, 2518, 2615, 2658, 3153, 3183, 3293, 3471, 4109], 'rapidly': [632], 'desensitizing': [633], 'current': [634, 1465, 4307], '(5Frerking': [635, 684], '6Kornau': [650, 699], 'H.-C.': [651, 700], 'Schenker': [652, 701], 'L.T.': [653, 702], 'Kennedy': [654, 703], 'M.B.': [655, 704], 'Seeberg': [656, 705], 'P.H.': [657, 706], 'Science.': [658, 707, 1063, 1165, 1183, 3087, 3904], '1995;': [659, 708, 1184], '269:': [660, 709], '1737-1740Crossref': [661, 710], '(1608)': [664, 713], 'KA1': [667], 'on': [670, 2035, 3133, 3932, 4004], 'other': [672, 2674], 'hand,': [673], 'are': [674, 786, 1209, 1294, 2515, 2844, 3650, 4020, 4149], 'functional': [675], 'only': [676, 2142, 2436, 2470], 'when': [677, 1721], 'coexpressed': [678], '-6,': [681], '-7': [683], '90,': [722], 'scaffold': [725], 'contains': [728], 'PDZ': [730, 763, 2454, 2478], 'domains,': [731], 'domain,': [734, 1307, 1311], 'guanylate': [737], '(7Kim': [740, 800], 'E.': [741, 801, 825, 1130, 1381, 1425, 2818, 3828, 3967, 4077, 4268], 'Cho': [742, 802], 'K.O.': [743, 803], 'Rothschild': [744, 804], 'Sheng': [746, 806, 826], 'Neuron.': [748, 808, 828, 851, 1765, 1860, 2265, 2402], '1996;': [749, 809, 917], '103-113Abstract': [751, 811], '(469)': [759, 819], 'The': [762, 1464, 1675, 2487, 3735, 4137, 4306], 'domains': [764, 2481], 'shown': [767, 2129, 2296, 2851, 2959, 3121, 3268, 3556], 'bind': [769, 1319, 1327, 2244, 2340, 3281], 'C': [772], 'terminus': [773], 'NMDA': [775, 792, 959, 979, 1042, 2724, 3073, 3890, 3952], 'NR2': [777], 'subunits,': [782], 'these': [784, 1496, 2841], 'interactions': [785], 'important': [787, 1089], 'for': [788, 1513, 1628, 1664, 1684, 2323, 2617, 2762, 3730, 3776, 4370, 4387, 4395], 'clustering': [790], 'postsynaptic': [798], 'membrane': [799], '8Niethammer': [822], 'Kim': [824], '1997;': [829, 1229, 1359, 1788, 2541, 2796, 3531, 3806, 3971, 4055], '16:': [830], '2157-2163Google': [831], '9Garcia': [833], 'E.P.': [834, 1748, 1843, 2248, 2385], 'Metha': [835, 1749, 1844, 2249, 2386], 'Blair': [837, 1751, 1846, 2251, 2388], 'L.A.': [838, 1752, 1847, 2252, 2389, 4245], 'Wells': [839, 1753, 1848, 2253, 2390], 'D.G.': [840, 1754, 1849, 2254, 2391], 'Shang': [841, 1755, 1850, 2255, 2392], 'Fukushima': [843, 1757, 1852, 2257, 2394], 'Fallon': [845, 1759, 1854, 2259, 2396], 'J.R.': [846, 1265, 1760, 1855, 2260, 2397, 2566, 3425, 3490], 'Garmer': [847, 1761, 1856, 2261, 2398], 'C.C.': [848, 1762, 1857, 2262, 2399], 'Marshall': [849, 1446, 1763, 1858, 1928, 1985, 2263, 2400], '1998;': [852, 1029, 1271, 1390, 1434, 1535, 1766, 1861, 1905, 1951, 2008, 2266, 2403, 2572, 2827, 3431, 3496, 3837, 4086], '21:': [853, 1767, 1862, 2267, 2404], '727-736Abstract': [854, 1768, 1863, 2268, 2405], 'In': [865, 970, 1192, 3595, 3913, 4008, 4285, 4342], 'addition,': [866, 4009], 'binds': [869, 1485], 'cytoskeletal': [871], 'linker': [872], 'proteins': [873, 877, 1802, 1837, 2120, 2350, 2419, 2447, 2457], 'cytoplasmic': [875], 'signaling': [876, 968, 1084, 2903, 3256, 3321, 3391, 3691, 3874, 4295, 4360], 'such': [878], 'nitric': [881], 'oxide': [882], 'synthase': [883, 1047], 'family': [887, 1301], 'tyrosine': [889], 'Fyn': [891], '(10Brenman': [892], 'J.E.': [893], 'Chao': [894], 'D.S.': [895, 915], 'Gee': [896], 'S.H.': [897], 'McGee': [898], 'A.W.': [899], 'Craven': [900], 'S.E.': [901, 4168], 'Santillano': [902], 'D.R.': [903], 'Wu': [904, 1156], 'Z.': [905, 1054, 1174, 3078, 3895], 'Huang': [906], 'Xia': [908], 'H.': [909, 933, 1255, 2556, 3415, 3480, 3955], 'Peters': [910], 'M.F.': [911, 1019, 4117, 4123], 'Froehner': [912], 'S.C.': [913], 'Bredt': [914], 'Cell.': [916], '84:': [918], '757-767Abstract': [919], '(1423)': [927], '11Tezuka': [930], 'Umemori': [932], 'Akiyama': [934], 'Nakanishi': [936], 'Yamamoto': [938], 'Proc.': [940, 4271], 'Natl.': [941, 4272], 'Acad.': [942, 4273], 'U.': [944, 4275], '1999;': [947, 1064, 3088, 3905, 4210, 4278], '96:': [948], '435-440Crossref': [949], '(329)': [952], 'appears': [956], 'link': [958], 'variety': [965], 'cellular': [967, 1083, 2902, 3390], 'cascades.': [969, 4361], 'transgenic': [971], 'lacking': [973], 'although': [975, 3361], 'localization': [977], 'at': [981, 1585, 2053, 3175, 4026], 'remains': [984], 'unaltered,': [985], 'frequency': [987], 'dependence': [988], 'NMDA-dependent': [990], 'long-term': [991, 994], 'potentiation': [992], 'depression': [995], 'shifted,': [997], 'spatial': [999], 'learning': [1000], 'severely': [1002], 'impaired': [1003], '(12Migaud': [1004], 'Charlesworth': [1006], 'Dempater': [1008], 'Webster': [1010], 'L.': [1011, 4192], 'Watabe': [1012], 'A.M.': [1013], 'Makhinson': [1014], 'He': [1016], 'Y.': [1017, 3965], 'Ramsay': [1018], 'Morris': [1020], 'R.M.': [1021], 'Morrison': [1022], 'J.H.': [1023, 4182], "O'Dell": [1024], 'T.J.': [1025], 'Grant': [1026], 'S.G.N.': [1027], 'Nature.': [1028, 1141, 1228, 1270, 2540, 2571, 3430, 3495, 3530, 4128], '396:': [1030], '433-439Crossref': [1031], '(946)': [1034], 'Suppression': [1037], 'inhibits': [1041, 3630], 'receptor-mediated': [1043, 4095], 'nitric-oxide': [1046], '(13Sattler': [1051, 3075, 3892], 'Xiong': [1053, 3077, 3894], 'Lu': [1055, 3079, 3896], 'W.-Y.': [1056, 3080, 3897], 'Hafner': [1057, 3081, 3898], 'MacDonald': [1059, 3083, 3900], 'J.F.': [1060, 3084, 3901, 4249], 'Tymianski': [1061, 3085, 3902], '284:': [1065, 3089, 3906], '1845-1848Crossref': [1066, 3090, 3907], '(707)': [1069, 3093, 3910], 'Scholar),': [1071, 1278, 2579, 2834, 3457, 3538, 3576], 'which': [1072, 1279, 1333, 1711, 2092, 2104, 2649, 3649], 'coupling': [1079], 'networks': [1085], 'an': [1088, 1516, 1809, 2124, 2626, 2645, 4099], 'their': [1092], 'biological': [1093], 'function': [1094], 'within': [1095], 'system.': [1099], 'stress-activated': [1104, 4358], 'mammalian': [1107], 'implicated': [1111, 3067, 3879], 'mediating': [1113], 'death': [1115, 1415, 3009, 3055, 3061, 4301], 'various': [1118], 'detrimental': [1119], 'stimuli': [1120], 'glutamate-mediated': [1123], '(14Kyriakis': [1125], 'Banerjee': [1127], 'Nikolakaki': [1129], 'Dai': [1131], 'Rubie': [1133], 'E.A.': [1134], 'Ahmad': [1135], 'Avruch': [1137, 1352, 2789, 3799, 4048], 'Woodgett': [1139], 'R.J.': [1140, 1162, 1164, 1180, 1223, 2535, 3525], '369:': [1143], '156-160Crossref': [1144], '(2402)': [1147], '15Derijard': [1150], 'B.': [1151, 1267, 2568, 3427, 3492], 'Raingeaud': [1152, 1177], 'Barrett': [1154], 'H': [1158], 'Han': [1159], 'Ulevitch': [1161], 'Davis': [1163, 1179, 1222, 2534, 3524, 4394], '267:': [1167], '682-685Crossref': [1168], '(1399)': [1170], '16Xia': [1173], 'Dickens': [1175], 'Greenberg': [1181], 'M.E.': [1182, 4237], '270:': [1185], '1326-1339Crossref': [1186], '(5016)': [1189], 'absence': [1194], 'JNK3,': [1196], 'form': [1199], 'JNK,': [1201], 'acid-induced': [1203, 2519], 'seizure': [1204, 3468], 'activity': [1205, 2622, 2765], 'degeneration': [1208, 2523, 3405, 3466], '(1Yang': [1212, 2524, 3514], 'D.D.': [1213, 2525, 3515], 'Kuan': [1214, 2526, 3516], 'C.-Y.': [1215, 2527, 3517], 'Whitmarsh': [1216, 2528, 3518], 'A.J.': [1217, 2529, 3519], 'Rincon': [1218, 2530, 3520], 'Zheng': [1220, 2532, 3522], 'T.S.': [1221, 2533, 3523], 'Rakis': [1224, 2536, 3526], 'Flavell': [1226, 2538, 3528], '389:': [1230, 2542, 3532], '865-869Crossref': [1231, 2543, 3533], '(1109)': [1234, 2546, 3536], 'phenotype': [1238, 3506], 'strikingly': [1240], 'observed': [1244, 2466, 3509], 'GluR6-deficient': [1246, 2513, 3459], '(2Mulle': [1248, 3408, 3473], 'C.': [1249, 1261, 1377, 1421, 2550, 2562, 2814, 3409, 3421, 3474, 3486, 3824, 4073], 'Seiler': [1250, 2551, 3410, 3475], 'Perez-Otano': [1252, 2553, 3412, 3477], 'I.': [1253, 1259, 2554, 2560, 3413, 3419, 3478, 3484], 'Dickinson-Anson': [1254, 2555, 3414, 3479], 'Castillo': [1256, 2557, 3416, 3481], 'P.E.': [1257, 2558, 3417, 3482, 3566], 'Bureau': [1258, 2559, 3418, 3483], 'Maron': [1260, 2561, 3420, 3485], 'Gage': [1262, 2563, 3422, 3487], 'F.H.': [1263, 2564, 3423, 3488], 'Mann': [1264, 2565, 3424, 3489], 'Bettler': [1266, 2567, 3426, 3491], 'Heinemmann': [1268, 2569, 3428, 3493], 'S.F.': [1269, 2570, 3429, 3494], '392:': [1272, 2573, 3432, 3497], '601-605Crossref': [1273, 2574, 3433, 3498], '(397)': [1276, 2577, 3436, 3501], 'Both': [1290, 2330], 'members': [1295], 'typified': [1302], 'middle': [1309], 'C-terminal': [1314, 2966], 'proline-rich': [1315, 1488, 2336], 'region': [1316, 1489, 2337], 'domain-containing': [1322], 'proteins.': [1323], 'MLK2/3': [1324, 2149, 2183, 2232, 2280, 2495, 2502, 2770, 2915, 3767, 3781, 4030], 'can': [1325], 'directly': [1326], 'activate': [1329, 1338, 2900, 4013], 'MKK4': [1330, 2864, 3306, 3378, 3646], 'MKK7,': [1332, 3648], 'turn': [1335], 'phosphorylate': [1336], '(17Hirai': [1340, 2777, 3787, 4036], 'Katoh': [1342, 2779, 3789, 4038], 'Terada': [1344, 2781, 3791, 4040], 'Kyriakis': [1346, 2783, 3793, 4042], 'Zon': [1348, 2785, 3795, 4044], 'L.I.': [1349, 2786, 3796, 4045], 'Rana': [1350, 1575, 2787, 3797, 4046, 4386], 'Ohno': [1354, 2791, 3801, 4050], 'Biol.': [1357, 1449, 1533, 1786, 1903, 1931, 1949, 1988, 2006, 2794, 3804, 3969, 4053, 4208], 'Chem.': [1358, 1450, 1534, 1787, 1904, 1932, 1950, 1989, 2007, 2795, 3805, 3970, 4054], '272:': [1360, 1789, 2797, 3807, 3972, 4056], '15167-15173Abstract': [1361, 2798, 3808, 4057], '(148)': [1369, 2806, 3816, 4065], '18Nagata': [1372, 2809, 3819, 4068], 'K.': [1373, 1417, 2810, 3820, 4069], 'Puls': [1374, 1418, 2811, 3821, 4070], 'Futter': [1376, 1420, 2813, 3823, 4072], 'Aspenstrom': [1378, 1422, 2815, 3825, 4074], 'Schaefer': [1380, 1424, 2817, 3827, 4076], 'Nakata': [1382, 1426, 2819, 3829, 4078], 'Hirokawa': [1384, 1428, 2821, 3831, 4080], 'N.': [1385, 1429, 2822, 3832, 4081], 'Hall': [1386, 1430, 1558, 2823, 3833, 4082], 'EMBO': [1388, 1432, 2825, 3835, 4084], '149-158Crossref': [1392, 1436, 2829, 3839, 4088], '(232)': [1395, 1439, 2832, 3842, 4091], 'Studies': [1398], 'from': [1399, 1572, 1634, 1646, 1652, 2027, 2143, 2156, 2185, 3209], 'our': [1400, 2067, 4344, 4381], 'group': [1401], 'others': [1403], 'show': [1404], 'induces': [1409, 2599, 3006, 3403], 'apoptotic': [1413, 2022, 3007, 3037, 3169, 3358], 'cell': [1414, 1521, 1709, 1735, 2116, 2145, 2158, 2187, 3008, 3060, 3134, 3288, 3359], '(18Nagata': [1416], '19Liu': [1442], 'Y.F.': [1443, 1531, 1780, 1901, 1925, 1947, 1982, 2004], 'Dorow': [1444, 1926, 1983], '275:': [1452, 1934, 1991], '19035-19040Abstract': [1453, 1935, 1992], '(71)': [1461, 1943, 2000], 'study': [1466, 4308, 4346], 'was': [1467, 1551, 1569, 1600, 1622, 1660, 1673, 1724, 1822, 1880, 1919, 1976, 2033, 2076, 2135, 2153, 2180, 2302, 2623, 2650, 2669, 3114, 3171, 3367, 3507], 'undertaken': [1468], 'investigate': [1470], 'molecular': [1472, 2321, 4320], 'mechanism': [1473, 4321], 'hypothesized': [1478], 'recruits': [1495], 'kinases': [1497, 2843], 'proximity': [1500], 'leading': [1503], 'Cell': [1510], 'culture': [1511], 'conditions': [1512], 'cells,': [1515, 3719, 3915], 'immortalized': [1517], 'hippocampal': [1519], 'line,': [1522], '293T': [1524, 1583, 1696, 1708, 2081, 2090, 2115, 2144, 2430], 'described': [1528, 1745, 1840, 1922, 1980], 'previously': [1529, 1746, 1841, 1923, 1979], '(20Liu': [1530, 1900], '273:': [1536, 1906, 1952, 2009], '28873-28877Abstract': [1537, 1907, 1953, 2010], '(120)': [1545, 1915, 1961, 2018], 'c-Myc-tagged': [1548, 1700, 2084, 2423], 'full-length': [1549, 1567], 'generous': [1553], 'gift': [1554, 1571], 'Dr.': [1556, 1573, 4384, 4392], '(University': [1559], 'College': [1560], 'London,': [1562], 'United': [1563], 'Kingdom)': [1564], 'Flag-tagged': [1566, 2087, 2426], '(Massachusetts': [1576], 'General': [1577], 'Hospital,': [1578], 'Boston,': [1579], 'MA).': [1580], '50': [1586], '60%': [1588, 3174], 'confluence': [1589], 'were': [1590, 1632, 1644, 1742, 1803, 1892, 1971, 2025, 2046, 2060, 2112, 2121, 2379, 2420, 2610, 3022, 3036], 'washed': [1591], 'once': [1592], 'serum-free': [1594], 'medium': [1595, 2699, 2744, 3051, 3157, 3999], 'prior': [1596], 'transfection.': [1598, 3027], 'Transfection': [1599], 'performed': [1601, 1977, 2034], 'using': [1602, 1808], 'LipofectAMINE': [1603], '(Life': [1604], 'Technologies,': [1605], 'Inc.)': [1606], 'according': [1607], "manufacturer's": [1610], 'instructions.': [1611], '10–20': [1612], 'μg': [1613, 1875], 'plasmids': [1615], '10': [1617, 2687, 2707, 2737, 3190, 3220], 'μl': [1618], 'LipofectAMINE/10-cm': [1620], 'plate': [1621], 'used': [1623, 1823, 1881], 'transfection': [1625, 2698, 3050, 3118, 3161, 3998], 'experiments.': [1626], 'Antibodies': [1627], 'purchased': [1633, 1645], 'Upstate': [1635], 'Biotechnology': [1636], 'Inc.,': [1637], 'M2,': [1639], '9E10,': [1640], 'antibody': [1643, 1672, 1676, 1723, 1810, 2206], 'Santa': [1647], 'Cruz.': [1648], 'A': [1649, 1817, 3504], 'peptide': [1650, 1728], 'selected': [1651], 'sequence': [1655], '(amino': [1656, 2353, 2357, 2361, 2365, 2369], 'acids': [1657, 2354, 2358, 2362, 2366, 2370, 2376, 2969], '248–265': [1658], 'DFGLAREWHKTTKMSAAG)': [1659], 'conjugated': [1661], 'KLH': [1663], 'immunization': [1665], 'rabbits,': [1667], 'resulting': [1670], 'polyclonal': [1671], 'purified.': [1674], 'recognizes': [1677], '105–110-kDa': [1679], 'band': [1681, 1716], 'expected': [1683], 'lysates': [1690, 1739, 2117, 2146, 2188, 2193], '9E10': [1693, 2100, 2138], 'immunoprecipitates': [1694, 2141, 2184, 2211, 2309], 'transfected': [1698], 'but': [1702, 2152, 2194, 2310, 2448, 2475], 'not': [1704, 1731, 2154, 2195, 2311, 2449, 2476, 2485, 2636, 3140, 3280, 3285, 3296, 3345, 3919], 'found': [1705, 2433, 3985], 'wild-type': [1707, 2157], 'lysates,': [1710], 'lack': [1712, 2093], 'MLK2.': [1713], 'no': [1718, 2717, 3131, 3215, 3930, 4001], 'longer': [1719], 'detectable': [1720, 3023], 'pre-absorbed': [1725], 'antigen': [1729], '(data': [1730, 2484, 3344], 'shown).': [1732, 2486], 'Preparation': [1733], 'whole': [1737, 2190], 'co-immunoprecipitation': [1741], 'conducted': [1743], '(9Garcia': [1747, 1842, 2247, 2384], '21Liu': [1779], 'Deth': [1781, 4366], 'C.R.': [1782], 'Devys': [1783], '8121-8124Abstract': [1790], '(92)': [1798], 'Precipitated': [1801], 'analyzed': [1804, 2122, 2624], 'Western': [1806], 'blotting': [1807], 'indicated': [1812], 'figure': [1815], 'legends.': [1816], 'Kodak': [1818], '440': [1819], 'Image': [1820], 'Station': [1821], 'analyze': [1825], 'quantify': [1827], 'blots.': [1828], 'Construction': [1829], 'purification': [1831], 'different': [1833, 2055], 'GST': [1835, 1877, 2348, 2417, 2445, 2455, 2460], 'fusion': [1836, 1878, 2349, 2418, 2446, 2456], '1–2': [1874], 'forin': [1882], 'vitro': [1883], 'binding': [1884, 3722, 3742, 3765], 'studies.': [1885], '16': [1886], 'h': [1887, 1967, 3025, 3030, 3159, 3177], 'after': [1888], 'transfection,': [1889, 1969, 2608], 'lysed': [1893], '1%': [1895], 'Triton': [1896], 'X-100': [1897], 'lysis': [1898], 'buffer': [1899], 'assayed': [1920], '(19Liu': [1924, 1981], '20Liu': [1946, 2003], '24': [1964, 3024, 3158], '48': [1966, 3029, 3176], 'following': [1968, 2607, 3026, 3160], 'fixed': [1972], 'TUNEL': [1974, 2031, 2040], 'staining': [1975, 2032], 'Most': [2021], 'detached': [2026], 'slides': [2029], 'remaining': [2037], 'attached': [2038], 'cells.': [2039, 2431, 2604, 2768, 2874, 2893, 2907, 3012, 3148, 3248, 3266, 3400, 3621, 4017], '(i.e.': [2043], 'living': [2044], 'cells)': [2045], 'counted': [2047, 2061], '×20': [2050], 'power': [2051], 'field': [2052], 'four': [2054, 2967], 'locations,': [2056], '600–800': [2058], 'control.': [2064, 2099], 'To': [2065, 2662, 3096], 'test': [2066, 3097], 'hypothesis,': [2068], 'we': [2069, 2161, 2580, 2593, 2678, 2835, 3000, 3250, 3598, 4289], 'first': [2070], 'examined': [2071, 2162, 2837], 'whether': [2072, 2163, 2595, 2838, 3002, 3252, 3586], 'associated': [2077, 2168, 2230, 2282, 2289, 3668], 'coexpressing': [2083], 'MLK3.': [2088], 'Wild-type': [2089], 'served': [2095], 'M2': [2102, 2140], 'antibodies,': [2103], 'detect': [2105], 'c-Myc': [2107], 'Flag': [2109], 'epitopes,': [2110], 'respectively,': [2111], 'incubated': [2113, 2421], 'immunoprecipitated': [2119], 'anti-PSD-95': [2125], 'monoclonal': [2126], 'antibody.': [2127, 2628], 'As': [2128, 2295, 2850, 2958, 3120, 3267], 'Fig.': [2131, 2298, 2853, 3123, 3270], '1': [2132, 2208, 2222, 2299], 'A,': [2133, 2962, 3125], 'detected': [2136, 2155, 2181, 2303], 'co-transfected': [2147], 'lysates.': [2159], 'Next,': [2160, 2999, 3249], 'brain.': [2178, 2294], 'precipitates': [2197, 2312], 'obtained': [2198, 2313], 'preimmune': [2200, 2315], 'serum': [2201], 'peptide-antigen': [2203], 'preabsorbed': [2204], '(Fig.': [2207, 2221, 2462, 2750, 3038, 3185, 3202, 3315], 'B).': [2209, 2998, 3187, 3204, 3230], 'Conversely,': [2210], 'contained': [2215], '(Fig.1': [2217], 'C)': [2218], 'D).': [2223, 3382], 'These': [2224, 2416, 2753, 2894, 3231, 3383, 4018], 'data': [2225, 2489, 2754, 2895, 3208, 3232, 3384, 4019], 'indicate': [2226, 3233, 3385], 'tissues.': [2239], 'Because': [2279, 2501, 2769], 'they': [2285], 'indirectly': [2288], 'E,': [2300], 'serum.': [2316], 'next': [2318, 2836], 'explored': [2319], 'basis': [2322], 'association': [2325], 'MLK2/3.': [2329], 'contain': [2334], 'PSD-95.': [2346, 2920], 'containing': [2351], 'PDZ1': [2352], '2–151),': [2355], 'PDZ2': [2356], '156–266),': [2359], 'PDZ3': [2360], '302–401),': [2363], '402–500),': [2367], 'GK': [2368, 2480], '512–724),': [2371], 'SH3-GK': [2373, 2442], '(SGS,': [2374], 'amino': [2375, 2968], '402–724)': [2377], 'constructed': [2380], 'subsequently': [2382], 'purified': [2383], 'expressed': [2428], 'bound': [2437, 2469], '(SGS)': [2444], 'any': [2451, 4002], 'alone': [2461, 2632], '2).': [2463], 'above': [2488], 'exist': [2497], 'strong': [2505, 2773], 'activator': [2506, 2774], 'resistant': [2516], '2Mulle': [2549], 'reasoned': [2581], 'might': [2585], 'MLK-JNK': [2590], 'pathway.': [2591, 3608, 3875], 'Thus,': [2592], 'investigated': [2594, 3001, 3251], 'Twenty-four': [2605], 'hours': [2606], 'treated': [2611], '100': [2613, 2656], 'μm': [2614, 2657, 2688, 2708, 2738, 3152, 3191], '5': [2618], 'min': [2619], 'anti-phospho-JNK': [2627], 'vector': [2631, 4390], '(negative': [2633], 'control)': [2634], 'did': [2635, 3284, 3295], 'induce': [2637, 3712, 4323], 'activation,': [2639, 3211], 'whereas': [2640], 'caused': [2644, 2727], 'elevated': [2646, 2763], 'activity,': [2648], 'further': [2651], 'increased': [2652, 3172], 'stimulation': [2654, 3558], '(Fig.3': [2660, 2997], 'A).': [2661, 2752, 3040], 'eliminate': [2663], 'possibility': [2665], 'due': [2670, 2886], 'receptors,': [2677], 'employed': [2679], 'series': [2681], 'antagonists.': [2684], 'Addition': [2685, 2719, 3041, 3149, 3188], 'CNQX,': [2689], 'AMPA': [2693, 2713], 'antagonist,': [2695, 2715], 'while': [2704, 3217, 3347], 'addition': [2705, 3291, 3987], 'GYKI': [2709, 3212], '52466,': [2710], 'selective': [2712, 2723, 3111, 3992], 'had': [2716, 3129, 3214, 3339, 4000], 'effect.': [2718], '(−)-AP-5,': [2721], 'antagonist': [2726], 'weaker': [2729, 3369], 'inhibition': [2730, 3366, 3587], 'activation.': [2734, 2849], 'Coaddition': [2735], '(−)-AP-5': [2739], 'CNQX': [2741, 3192, 3223], 'nearly': [2745, 2973, 3224], 'completely': [2746, 2974, 3052, 3225], 'blocked': [2747, 2975, 3053, 3226], 'largely': [2760], 'accounts': [2761], 'either': [2839, 2927], 'B,': [2855], 'coexpression': [2856], 'Dominant': [2875], 'appeared': [2878], 'less': [2881], 'effective.': [2882], 'its': [2888, 3741], 'lower': [2889], 'abundance': [2890], 'MLK2/3-mediated': [2901, 3255, 3389], 'cascades': [2904, 3257, 3322, 3392, 4296], 'believe': [2909], 'anchors': [2912], 'activates': [2914, 3388, 3603, 4032], 'via': [2916, 3393, 3605], 'complex': [2918, 2949, 3692, 3853], 'involving': [2919], 'If': [2921], 'this': [2922, 3596], 'hypothesis': [2923], 'correct,': [2925], 'then': [2926], 'deletion': [2928, 2963], 'mutation': [2936, 3746], 'should': [2943], 'disrupt': [2944], 'assembly': [2945, 3849], 'GluR6·PSD-95·MLK2/3': [2948, 3852], 'block': [2951], 'receptor.': [2957, 2981, 3640, 3937], 'Fig.3': [2961], '(GluR6Δ)': [2972], 'mutated': [2987, 3276, 4314], '(W470A)': [2990], 'rapid': [3017], 'apoptosis,': [3018], 'TUNEL-positive': [3020], 'At': [3028], 'post-transfection,': [3031, 3178], 'about': [3032], '30–35%': [3033], 'nonspecific': [3044], 'caspase': [3045], 'inhibitor,': [3046, 3113, 3995], 'zDEVD-frm,': [3047], '(Fig.4': [3056, 3229, 3381], 'A),': [3057], 'supporting': [3058], 'apoptotic.': [3063], 'has': [3065, 3877, 3929, 4227], 'nNOS': [3071, 3101, 3112, 3127, 3138, 3888, 3916, 3927], 'cells,N': [3108], 'ω-propylarginine,': [3109], 'added': [3115], 'medium.': [3119], 'inhibitor': [3128, 3928], 'almost': [3130, 4150], 'effect': [3132, 3216, 3343, 3931, 4003], 'death,': [3135, 3289, 3360], 'suggesting': [3136, 3318, 3539, 3682, 3720, 3763], 'does': [3139, 3279, 3918], 'contribute': [3141, 3920, 4298], '500': [3151], 'enhanced': [3163], 'toxicity:': [3165, 3196], 'number': [3167, 4138], 'compared': [3179], '40%': [3181], 'without': [3182], 'over': [3197], '80%': [3198], 'survived': [3201], 'Consistent': [3205], '52466': [3213], 'coaddition': [3218], 'μm(−)-AP5': [3221], 'induction': [3242, 3330, 3777, 3884], 'C,': [3272], 'cause': [3286], 'significant': [3287, 3326], 'enhance': [3297], 'apoptosis': [3311, 3397, 3618, 3716, 3759, 3933], 'D),': [3317], 'MLK2-mediated': [3320, 4294], 'do': [3323], 'play': [3324, 4098], 'smaller': [3341], 'inhibitory': [3342], 'shown)': [3346], 'extent': [3363], 'much': [3368], 'than': [3370], 'mediate': [3396], 'hippocampus': [3407], 'Scholar,22Telfeian': [3438], 'A.E.': [3439], 'Federoff': [3440], 'H.J.': [3441], 'Leone': [3442], 'During': [3444], 'M.J.': [3445], 'Williamson': [3446], 'Dis.': [3449], '7:': [3451], '362-374Crossref': [3452], '(41)': [3455], 'exhibit': [3461], 'JNK3': [3511], 'knockout': [3512], 'GluR6.': [3551, 3696], 'Although': [3552], 'some': [3553], 'reports': [3554, 3939], 'mediates': [3562, 3582, 3740], '(23Schauwecker': [3565], 'Brain': [3567], 'Res.': [3568], '884:': [3570], '116-128Crossref': [3571], '(72)': [3574], 'it': [3577], 'unclear': [3579], 'how': [3580, 4351], 'blocks': [3591], 'study,': [3597], 'PSD-95-MLK2/3-signaling': [3607], 'causes': [3614], 'Additionally,': [3641], 'immediate': [3651], 'intact': [3674], 'tissues,': [3681], 'assemble': [3688], 'into': [3689, 4350], 'abolished': [3705], 'ability': [3707], 'necessary': [3729], 'occur.': [3734], 'MLK2/3;': [3744], 'attenuates': [3754], 'constitutively': [3784], 'active': [3785], 'explanation': [3846], 'occurs': [3854], 'promotes': [3861], 'exposure': [3862], 'ATP': [3868], 'downstream': [3873], 'because': [3925], 'Some': [3938], 'p38': [3942, 3993], 'MAPK': [3943, 3994, 4014], '(24Kawasaki': [3954], 'Morooka': [3956], 'Shimohama': [3958], 'Kimura': [3960], 'Hirano': [3962], 'Gotoh': [3964], 'Nishida': [3966], '18518-18521Abstract': [3973], '(382)': [3981], 'SB': [3989], '203580,': [3990], 'death.': [4007, 4325], 'failed': [4011], 'consistent': [4021], 'fact': [4024], 'that,': [4025], 'moderate': [4027], 'levels,': [4029], 'selectively': [4031], 'MKK4/7-JNK': [4034], 'pathway': [4035], 'essential': [4100], 'pathogenesis': [4104, 4339], 'intra-striatal': [4106], 'injection': [4107], 'rats': [4112], 'creates': [4113], 'HD-like': [4114], 'pathology': [4115], '(25Beal': [4116], 'Kowall': [4118], 'N.W.': [4119], 'Ellison': [4120], 'D.W.': [4121], 'Mazurek': [4122], 'Swartz': [4124], 'K.J.': [4125], 'Martin': [4126], 'J.B.': [4127, 4195], '1986;': [4129], '321:': [4130], '168-171Crossref': [4131], '(1103)': [4134], 'high': [4146], 'affinity': [4147], 'absent': [4151], 'brains': [4154], 'HD': [4156, 4235], 'patients': [4157], 'HD-transgenic': [4159], '(26Wagster': [4161], 'M.V.': [4162], 'Hedreeen': [4163], 'J.C.': [4164], 'Peyser': [4165], 'C.E.': [4166], 'Folstein': [4167], 'Ross': [4169], 'C.A.': [4170], 'Exp.': [4171], 'Neurol.': [4172], '127:': [4174], '70-75Crossref': [4175], '(39)': [4178], '27Cha': [4181], 'Frey': [4183], 'A.S.': [4184], 'Alsdorf': [4185], 'S.A.': [4186], 'Kerner': [4187], 'J.A.': [4188], 'Kosinski': [4189], 'C.M.': [4190], 'Mangiarini': [4191], 'Penney': [4193], 'Jr,': [4194], 'Davies': [4196], 'S.W.': [4197], 'Bates': [4198], 'G.P.': [4199], 'Young': [4200], 'A.B.': [4201], 'Philos.': [4202], 'Trans.': [4203], 'Soc.': [4205], 'Lond.': [4206], 'B': [4207], '354:': [4211], '981-989Crossref': [4212], '(187)': [4215], 'Moreover,': [4218], 'TAA': [4220], 'repeat': [4221], 'polymorphism': [4222], 'gene': [4226], 'linked': [4229], 'younger': [4232], 'onset': [4233], '(28MacDonald': [4236], 'Vonsattel': [4238], 'J.P.': [4239], 'Shrinidhi': [4240], 'Couropmitree': [4242], 'N.N.': [4243], 'Cupples': [4244], 'Bird': [4246], 'E.D.': [4247], 'Gusella': [4248], 'Myers': [4250], 'R.H.': [4251], 'Neurology.': [4252], '12:': [4254], '1330-1332Google': [4255], '29Rubinsztein': [4257], 'D.C.': [4258], 'Leggo': [4259], 'Chiano': [4261], 'Dodge': [4263], 'Norbury': [4265], 'G.': [4266], 'Rosser': [4267], 'Craufurd': [4269], '94:': [4279], '3872-3876Crossref': [4280], '(204)': [4282], 'previous': [4287], 'report,': [4288], 'showed': [4290], 'polyglutamine-expanded': [4304], 'huntingtin.': [4305], 'huntingtin': [4315], 'would': [4327], 'help': [4328], 'explain': [4330], 'potential': [4332], 'HD.': [4341], 'summary,': [4343], 'present': [4345], 'gives': [4347], 'new': [4348], 'insight': [4349], 'thank': [4363], 'Drs.': [4364], 'Grate': [4369], 'helpful': [4371], 'suggestions': [4372], 'reading': [4375], 'manuscript.': [4378], 'express': [4380], 'gratitude': [4382], 'vectors.': [4397]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086507786', 'counts_by_year': [{'year': 2023, 'cited_by_count': 2}, {'year': 2022, 'cited_by_count': 1}, {'year': 2021, 'cited_by_count': 2}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 2}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 3}, {'year': 2014, 'cited_by_count': 5}, {'year': 2013, 'cited_by_count': 6}, {'year': 2012, 'cited_by_count': 2}], 'updated_date': '2025-01-09T14:38:56.059134', 'created_date': '2016-06-24'}