Title: The eukaryotic translation initiation factor 4E (eIF4E) and HuR RNA operons collaboratively regulate the expression of survival and proliferative genes
Abstract: eIF4E, HuR and AUF1 act as important regulators of gene expression at the post-transcriptional level and play pivotal role in various cellular processes ranging from immune response to tumorigenesis. Our recent study reveals that these factors are functionally linked. In this review we discuss the aspects of eIF4E-HuR-AUF1 functional relationship in the context of the growing field of ribonomics.