Get quick answers to your questions about the article from our AI researcher chatbot
{'id': 'https://openalex.org/W2086194713', 'doi': 'https://doi.org/10.7326/0003-4819-118-10-199305150-00022', 'title': 'Intravenous Gammaglobulin in a Hypothyroid Patient with the Antiphospholipid Antibody Syndrome', 'display_name': 'Intravenous Gammaglobulin in a Hypothyroid Patient with the Antiphospholipid Antibody Syndrome', 'publication_year': 1993, 'publication_date': '1993-05-15', 'ids': {'openalex': 'https://openalex.org/W2086194713', 'doi': 'https://doi.org/10.7326/0003-4819-118-10-199305150-00022', 'mag': '2086194713', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8470864'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/0003-4819-118-10-199305150-00022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'letter', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5006927586', 'display_name': 'Yasuko Nakamura', 'orcid': 'https://orcid.org/0000-0002-0660-4126'}, 'institutions': [], 'countries': [], 'is_corresponding': True, 'raw_author_name': 'Yasuko Nakamura', 'raw_affiliation_strings': [], 'affiliations': []}], 'institution_assertions': [], 'countries_distinct_count': 0, 'institutions_distinct_count': 0, 'corresponding_author_ids': ['https://openalex.org/A5006927586'], 'corresponding_institution_ids': [], 'apc_list': None, 'apc_paid': None, 'fwci': None, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 6, 'citation_normalized_percentile': {'value': 0.586694, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 72, 'max': 74}, 'biblio': {'volume': '118', 'issue': '10', 'first_page': '827', 'last_page': '827'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T12919', 'display_name': 'Blood disorders and treatments', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, 'topics': [{'id': 'https://openalex.org/T12919', 'display_name': 'Blood disorders and treatments', 'score': 0.9973, 'subfield': {'id': 'https://openalex.org/subfields/1311', 'display_name': 'Genetics'}, 'field': {'id': 'https://openalex.org/fields/13', 'display_name': 'Biochemistry, Genetics and Molecular Biology'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}, {'id': 'https://openalex.org/T11221', 'display_name': 'Bone health and treatments', 'score': 0.9673, 'subfield': {'id': 'https://openalex.org/subfields/2730', 'display_name': 'Oncology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12286', 'display_name': 'Erythrocyte Function and Pathophysiology', 'score': 0.9534, 'subfield': {'id': 'https://openalex.org/subfields/2737', 'display_name': 'Physiology'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/lupus-anticoagulant', 'display_name': 'Lupus anticoagulant', 'score': 0.45925328}, {'id': 'https://openalex.org/keywords/anti-thyroid-autoantibodies', 'display_name': 'Anti-thyroid autoantibodies', 'score': 0.4125757}], 'concepts': [{'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.9621266}, {'id': 'https://openalex.org/C2776874634', 'wikidata': 'https://www.wikidata.org/wiki/Q582207', 'display_name': 'Antiphospholipid syndrome', 'level': 3, 'score': 0.51256895}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.49708155}, {'id': 'https://openalex.org/C2778696486', 'wikidata': 'https://www.wikidata.org/wiki/Q11835644', 'display_name': 'Thyroiditis', 'level': 3, 'score': 0.49583992}, {'id': 'https://openalex.org/C79162176', 'wikidata': 'https://www.wikidata.org/wiki/Q5520338', 'display_name': 'Gamma globulin', 'level': 3, 'score': 0.48908383}, {'id': 'https://openalex.org/C2780022809', 'wikidata': 'https://www.wikidata.org/wiki/Q5786759', 'display_name': 'Lupus anticoagulant', 'level': 3, 'score': 0.45925328}, {'id': 'https://openalex.org/C163764329', 'wikidata': 'https://www.wikidata.org/wiki/Q785022', 'display_name': 'Autoantibody', 'level': 3, 'score': 0.4571528}, {'id': 'https://openalex.org/C159654299', 'wikidata': 'https://www.wikidata.org/wiki/Q79460', 'display_name': 'Antibody', 'level': 2, 'score': 0.42191836}, {'id': 'https://openalex.org/C50181227', 'wikidata': 'https://www.wikidata.org/wiki/Q1943709', 'display_name': 'Anti-thyroid autoantibodies', 'level': 4, 'score': 0.4125757}, {'id': 'https://openalex.org/C526584372', 'wikidata': 'https://www.wikidata.org/wiki/Q16399', 'display_name': 'Thyroid', 'level': 2, 'score': 0.40231964}, {'id': 'https://openalex.org/C90924648', 'wikidata': 'https://www.wikidata.org/wiki/Q120569', 'display_name': 'Gastroenterology', 'level': 1, 'score': 0.38611406}, {'id': 'https://openalex.org/C187212893', 'wikidata': 'https://www.wikidata.org/wiki/Q123028', 'display_name': 'Pediatrics', 'level': 1, 'score': 0.38455096}, {'id': 'https://openalex.org/C203014093', 'wikidata': 'https://www.wikidata.org/wiki/Q101929', 'display_name': 'Immunology', 'level': 1, 'score': 0.24889612}], 'mesh': [{'descriptor_ui': 'D016736', 'descriptor_name': 'Antiphospholipid Syndrome', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D007037', 'descriptor_name': 'Hypothyroidism', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D016756', 'descriptor_name': 'Immunoglobulins, Intravenous', 'qualifier_ui': 'Q000627', 'qualifier_name': 'therapeutic use', 'is_major_topic': True}, {'descriptor_ui': 'D013921', 'descriptor_name': 'Thrombocytopenia', 'qualifier_ui': 'Q000628', 'qualifier_name': 'therapy', 'is_major_topic': True}, {'descriptor_ui': 'D000368', 'descriptor_name': 'Aged', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016736', 'descriptor_name': 'Antiphospholipid Syndrome', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D005260', 'descriptor_name': 'Female', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006801', 'descriptor_name': 'Humans', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007037', 'descriptor_name': 'Hypothyroidism', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D007037', 'descriptor_name': 'Hypothyroidism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D016756', 'descriptor_name': 'Immunoglobulins, Intravenous', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D013921', 'descriptor_name': 'Thrombocytopenia', 'qualifier_ui': 'Q000276', 'qualifier_name': 'immunology', 'is_major_topic': False}, {'descriptor_ui': 'D013921', 'descriptor_name': 'Thrombocytopenia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.7326/0003-4819-118-10-199305150-00022', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S119722071', 'display_name': 'Annals of Internal Medicine', 'issn_l': '0003-4819', 'issn': ['0003-4819', '1539-3704'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310316812', 'host_organization_name': 'American College of Physicians', 'host_organization_lineage': ['https://openalex.org/P4310316812'], 'host_organization_lineage_names': ['American College of Physicians'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8470864', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'display_name': 'Good health and well-being', 'id': 'https://metadata.un.org/sdg/3', 'score': 0.84}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 0, 'referenced_works': [], 'related_works': ['https://openalex.org/W4384821746', 'https://openalex.org/W3214406228', 'https://openalex.org/W3196309484', 'https://openalex.org/W3092459053', 'https://openalex.org/W3035878350', 'https://openalex.org/W2376859318', 'https://openalex.org/W2161939736', 'https://openalex.org/W2123269384', 'https://openalex.org/W2079160440', 'https://openalex.org/W2029794473'], 'abstract_inverted_index': {'Letters15': [0], 'May': [1, 319, 332], '1993Intravenous': [2], 'Gammaglobulin': [3], 'in': [4, 218, 261, 268, 299, 304, 313], 'a': [5, 93, 99, 130, 146], 'Hypothyroid': [6], 'Patient': [7], 'with': [8, 68, 96, 129, 168, 220, 224, 265, 306], 'the': [9, 229, 291], 'Antiphospholipid': [10, 292], 'Antibody': [11], 'SyndromeYasuko': [12], 'Nakamura,': [13, 22], 'MD,': [14, 17], 'Yukiko': [15, 30], 'Uchida,': [16, 31], 'and': [18, 39, 50, 98, 118, 132, 134, 190, 216, 278, 297], 'Masami': [19, 40], 'Murakami,': [20, 41], 'MDYasuko': [21], 'MDSearch': [23, 32, 42], 'for': [24, 33, 43], 'more': [25, 34, 44], 'papers': [26, 35, 45], 'by': [27, 36, 46, 87, 337], 'this': [28, 37, 47], 'author,': [29, 38], 'authorAuthor,': [48], 'Article,': [49, 277], 'Disclosure': [51, 279], 'Informationhttps://doi.org/10.7326/0003-4819-118-10-199305150-00022': [52], 'SectionsAboutFull': [53], 'TextPDF': [54], 'ToolsAdd': [55], 'to': [56, 126], 'favoritesDownload': [57], 'CitationsTrack': [58], 'CitationsPermissions': [59], 'ShareFacebookTwitterLinkedInRedditEmail': [60], 'TO': [61], 'THE': [62], 'EDITOR:Many': [63], 'reports': [64], 'of': [65, 82, 111, 115, 136, 141, 213, 235, 290, 340], 'thrombocytopenia': [66, 97], 'associated': [67, 167], 'autoimmune': [69, 83], 'thyroid': [70, 84, 214], 'disease': [71, 85], 'have': [72], 'occurred': [73], 'since': [74], "Jackson's": [75], 'first': [76], 'description': [77], '[1].': [78], 'Most': [79], 'were': [80], 'cases': [81], 'complicated': [86], 'idiopathic': [88], 'thrombocytopenic': [89], 'purpura.': [90], 'We': [91], 'describe': [92], 'hypothyroid': [94], 'patient': [95], 'paradoxical': [100], 'thromboembolic': [101], 'episode,': [102], 'diagnosed': [103], 'as': [104, 153], 'having': [105], 'an': [106], 'antiphospholipid': [107, 188], 'antibody': [108, 312, 316], 'syndrome': [109, 317], 'because': [110], 'high': [112], 'serum': [113], 'levels': [114], 'anticardiolipin': [116], 'antibodies': [117, 260], 'lupus': [119], 'anticoagulant.A': [120], '65-year-old': [121], 'Japanese': [122], 'woman': [123], 'was': [124, 158], 'admitted': [125], 'our': [127], 'hospital': [128], 'goiter': [131], 'signs': [133], 'symptoms': [135], 'hypothyroidism.': [137], 'At': [138], '53': [139], 'years': [140], 'age,': [142], 'she': [143], 'had': [144, 145], 'cerebral': [147], 'infarction.': [148], 'Laboratory': [149], 'data': [150], 'confirmed': [151], 'hypothyroidism': [152], 'follows:': [154], 'The': [155], 'free-triiodothyronine': [156], 'value': [157], '...References1.': [159], 'Jackson': [160], 'AS,': [161], 'Madison': [162], 'L.': [163, 211], 'Acute': [164], 'hemorrhagic': [165], 'purpura': [166], 'exophthalmic': [169], 'goiter.': [170], 'JAMA.': [171], '1931;': [172], '96:38-9.': [173], 'Google': [174, 197, 243, 274], 'Scholar2.': [175], 'Parke': [176], 'A,': [177, 200, 206], 'Maier': [178], 'D,': [179, 181], 'Wilson': [180], 'Andreoli': [182], 'J,': [183], 'Ballow': [184], 'M.': [185], 'Intravenous': [186], '-globulin,': [187], 'antibodies,': [189], 'pregnancy.': [191], 'Ann': [192], 'Intern': [193], 'Med.': [194], '1989;': [195], '110:495-6.': [196], 'Scholar3.': [198], 'Antonelli': [199], 'Bombardieri': [201], 'S,': [202, 209], 'Alberti': [203], 'B,': [204], 'Saracino': [205], 'De': [207], 'Vita': [208], 'Baschieri': [210], 'Variations': [212], 'function': [215], 'autoantibodies': [217], 'patients': [219], "Hashimoto's": [221], 'thyroiditis': [222], 'treated': [223], 'intravenous': [225], 'gammaglobulin.': [226], 'Presented': [227], 'at': [228], 'International': [230], 'Hashimoto': [231, 236], 'Symposium': [232], 'Eightieth': [233], 'Anniversary': [234], 'Disease,': [237], '2-5': [238], 'December': [239], '1992,': [240], 'Fukuoka,': [241], 'Japan.': [242], 'Scholar4.': [244], 'Marongiu': [245], 'F,': [246], 'Conti': [247], 'M,': [248], 'Martas': [249], 'ML,': [250], 'Sorano': [251], 'GG,': [252], 'Mameli': [253], 'G,': [254, 256], 'Salis': [255], 'et': [257], 'al.': [258], 'Anticardiolipin': [259], "Grave's": [262], 'disease:': [263], 'relationship': [264], 'thrombin': [266], 'activity': [267], 'vivo.': [269], 'Thrombosis': [270], 'Research.': [271], '1991;': [272], '64:745-9.': [273], 'Scholar': [275], 'Author,': [276], 'InformationAffiliations:': [280], 'PreviousarticleNextarticle': [281], 'Advertisement': [282], 'FiguresReferencesRelatedDetails': [283], 'Metrics': [284], 'Cited': [285], 'ByChapter': [286], '13': [287], 'Endocrine': [288], 'Manifestations': [289], 'SyndromeChapter': [293], '17': [294], 'Autoimmune': [295, 301], 'Hypothyroidism': [296], 'Hyperthyroidism': [298], 'Systemic': [300], 'DiseaseThyroid': [302], 'Disease': [303], 'Patients': [305], 'Idiopathic': [307], 'Thrombocytopenia:': [308], 'A': [309], 'Cohort': [310], 'StudyAnticardiolipin': [311], 'vascular': [314], 'parkinsonismAntiphospholipid': [315], '15': [318, 331], '1993Volume': [320], '118,': [321], 'Issue': [322, 329], '10Page:': [323], '827-828KeywordsAntibodiesAntibody': [324], 'therapyAutoantibodiesHypothyroidismPlateletsThyroidThyroid': [325], 'diseasesThyroid': [326], 'hormonesThyroid-stimulating': [327], 'hormoneThyroxine': [328], 'Published:': [330], '1993': [333, 336], 'CopyrightCopyright': [334], '©': [335], 'American': [338], 'College': [339], 'Physicians.': [341], 'All': [342], 'Rights': [343], 'Reserved.PDF': [344], 'DownloadLoading': [345], '...': [346]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086194713', 'counts_by_year': [], 'updated_date': '2024-12-15T16:56:35.545735', 'created_date': '2016-06-24'}