Publication Information

{'id': 'https://openalex.org/W2086184661', 'doi': 'https://doi.org/10.1007/bf00823590', 'title': 'No evidence for mediation of ischemic preconditioning by alpha1-adrenergic signal transduction pathway or protein kinase C in the isolated rat heart', 'display_name': 'No evidence for mediation of ischemic preconditioning by alpha1-adrenergic signal transduction pathway or protein kinase C in the isolated rat heart', 'publication_year': 1996, 'publication_date': '1996-10-01', 'ids': {'openalex': 'https://openalex.org/W2086184661', 'doi': 'https://doi.org/10.1007/bf00823590', 'mag': '2086184661', 'pmid': 'https://pubmed.ncbi.nlm.nih.gov/8842504'}, 'language': 'en', 'primary_location': {'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf00823590', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S131791641', 'display_name': 'Cardiovascular Drugs and Therapy', 'issn_l': '0920-3206', 'issn': ['0920-3206', '1573-7241'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, 'type': 'article', 'type_crossref': 'journal-article', 'indexed_in': ['crossref', 'pubmed'], 'open_access': {'is_oa': False, 'oa_status': 'closed', 'oa_url': None, 'any_repository_has_fulltext': False}, 'authorships': [{'author_position': 'first', 'author': {'id': 'https://openalex.org/A5012226095', 'display_name': 'Johannes Moolman', 'orcid': 'https://orcid.org/0009-0006-4497-2655'}, 'institutions': [{'id': 'https://openalex.org/I2802694459', 'display_name': 'Tygerberg Hospital', 'ror': 'https://ror.org/01hs8x754', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307091933', 'https://openalex.org/I2802694459']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Johannes Albertus Moolman', 'raw_affiliation_strings': ['Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa', 'institution_ids': ['https://openalex.org/I2802694459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5064761619', 'display_name': 'Sonia Genade', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802694459', 'display_name': 'Tygerberg Hospital', 'ror': 'https://ror.org/01hs8x754', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307091933', 'https://openalex.org/I2802694459']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Sonia Genade', 'raw_affiliation_strings': ['Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa', 'institution_ids': ['https://openalex.org/I2802694459']}]}, {'author_position': 'middle', 'author': {'id': 'https://openalex.org/A5110138979', 'display_name': 'Erna Tromp', 'orcid': None}, 'institutions': [{'id': 'https://openalex.org/I2802694459', 'display_name': 'Tygerberg Hospital', 'ror': 'https://ror.org/01hs8x754', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307091933', 'https://openalex.org/I2802694459']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Erna Tromp', 'raw_affiliation_strings': ['Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa', 'institution_ids': ['https://openalex.org/I2802694459']}]}, {'author_position': 'last', 'author': {'id': 'https://openalex.org/A5029270707', 'display_name': 'Amanda Lochner', 'orcid': 'https://orcid.org/0000-0002-6847-5091'}, 'institutions': [{'id': 'https://openalex.org/I2802694459', 'display_name': 'Tygerberg Hospital', 'ror': 'https://ror.org/01hs8x754', 'country_code': 'ZA', 'type': 'healthcare', 'lineage': ['https://openalex.org/I1307091933', 'https://openalex.org/I2802694459']}], 'countries': ['ZA'], 'is_corresponding': False, 'raw_author_name': 'Amanda Lochner', 'raw_affiliation_strings': ['Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa'], 'affiliations': [{'raw_affiliation_string': 'Department of Internal Medicine, Faculty of Medicine, Tygerberg, South Africa', 'institution_ids': ['https://openalex.org/I2802694459']}]}], 'institution_assertions': [], 'countries_distinct_count': 1, 'institutions_distinct_count': 1, 'corresponding_author_ids': [], 'corresponding_institution_ids': [], 'apc_list': {'value': 3390, 'currency': 'EUR', 'value_usd': 4190, 'provenance': 'doaj'}, 'apc_paid': None, 'fwci': 3.151, 'has_fulltext': True, 'fulltext_origin': 'ngrams', 'cited_by_count': 31, 'citation_normalized_percentile': {'value': 0.719361, 'is_in_top_1_percent': False, 'is_in_top_10_percent': False}, 'cited_by_percentile_year': {'min': 88, 'max': 89}, 'biblio': {'volume': '10', 'issue': '2', 'first_page': '125', 'last_page': '136'}, 'is_retracted': False, 'is_paratext': False, 'primary_topic': {'id': 'https://openalex.org/T11057', 'display_name': 'Cardiac Ischemia and Reperfusion', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, 'topics': [{'id': 'https://openalex.org/T11057', 'display_name': 'Cardiac Ischemia and Reperfusion', 'score': 1.0, 'subfield': {'id': 'https://openalex.org/subfields/2734', 'display_name': 'Pathology and Forensic Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T10645', 'display_name': 'Cardiac Arrest and Resuscitation', 'score': 0.9896, 'subfield': {'id': 'https://openalex.org/subfields/2711', 'display_name': 'Emergency Medicine'}, 'field': {'id': 'https://openalex.org/fields/27', 'display_name': 'Medicine'}, 'domain': {'id': 'https://openalex.org/domains/4', 'display_name': 'Health Sciences'}}, {'id': 'https://openalex.org/T12963', 'display_name': 'Anesthesia and Neurotoxicity Research', 'score': 0.988, 'subfield': {'id': 'https://openalex.org/subfields/2806', 'display_name': 'Developmental Neuroscience'}, 'field': {'id': 'https://openalex.org/fields/28', 'display_name': 'Neuroscience'}, 'domain': {'id': 'https://openalex.org/domains/1', 'display_name': 'Life Sciences'}}], 'keywords': [{'id': 'https://openalex.org/keywords/chelerythrine', 'display_name': 'Chelerythrine', 'score': 0.86605823}, {'id': 'https://openalex.org/keywords/ischemic-preconditioning', 'display_name': 'Ischemic Preconditioning', 'score': 0.78630733}, {'id': 'https://openalex.org/keywords/bisindolylmaleimide', 'display_name': 'Bisindolylmaleimide', 'score': 0.602589}, {'id': 'https://openalex.org/keywords/phenylephrine', 'display_name': 'Phenylephrine', 'score': 0.42965207}], 'concepts': [{'id': 'https://openalex.org/C2776108454', 'wikidata': 'https://www.wikidata.org/wiki/Q5089853', 'display_name': 'Chelerythrine', 'level': 4, 'score': 0.86605823}, {'id': 'https://openalex.org/C71924100', 'wikidata': 'https://www.wikidata.org/wiki/Q11190', 'display_name': 'Medicine', 'level': 0, 'score': 0.8052505}, {'id': 'https://openalex.org/C2779311647', 'wikidata': 'https://www.wikidata.org/wiki/Q17148404', 'display_name': 'Ischemic preconditioning', 'level': 3, 'score': 0.78630733}, {'id': 'https://openalex.org/C195794163', 'wikidata': 'https://www.wikidata.org/wiki/Q420877', 'display_name': 'Protein kinase C', 'level': 3, 'score': 0.7552122}, {'id': 'https://openalex.org/C2780648677', 'wikidata': 'https://www.wikidata.org/wiki/Q425296', 'display_name': 'Prazosin', 'level': 4, 'score': 0.71871334}, {'id': 'https://openalex.org/C2777314051', 'wikidata': 'https://www.wikidata.org/wiki/Q27075304', 'display_name': 'Bisindolylmaleimide', 'level': 4, 'score': 0.602589}, {'id': 'https://openalex.org/C541997718', 'wikidata': 'https://www.wikidata.org/wiki/Q188151', 'display_name': 'Ischemia', 'level': 2, 'score': 0.5525963}, {'id': 'https://openalex.org/C98274493', 'wikidata': 'https://www.wikidata.org/wiki/Q128406', 'display_name': 'Pharmacology', 'level': 1, 'score': 0.48571143}, {'id': 'https://openalex.org/C158453852', 'wikidata': 'https://www.wikidata.org/wiki/Q4684738', 'display_name': 'Adrenergic', 'level': 3, 'score': 0.46685535}, {'id': 'https://openalex.org/C126322002', 'wikidata': 'https://www.wikidata.org/wiki/Q11180', 'display_name': 'Internal medicine', 'level': 1, 'score': 0.4328515}, {'id': 'https://openalex.org/C2777952589', 'wikidata': 'https://www.wikidata.org/wiki/Q421910', 'display_name': 'Phenylephrine', 'level': 3, 'score': 0.42965207}, {'id': 'https://openalex.org/C40465926', 'wikidata': 'https://www.wikidata.org/wiki/Q410568', 'display_name': 'Adrenergic receptor', 'level': 3, 'score': 0.4228167}, {'id': 'https://openalex.org/C62478195', 'wikidata': 'https://www.wikidata.org/wiki/Q828130', 'display_name': 'Signal transduction', 'level': 2, 'score': 0.3819127}, {'id': 'https://openalex.org/C170493617', 'wikidata': 'https://www.wikidata.org/wiki/Q208467', 'display_name': 'Receptor', 'level': 2, 'score': 0.17586112}, {'id': 'https://openalex.org/C95444343', 'wikidata': 'https://www.wikidata.org/wiki/Q7141', 'display_name': 'Cell biology', 'level': 1, 'score': 0.10831112}, {'id': 'https://openalex.org/C2776885963', 'wikidata': 'https://www.wikidata.org/wiki/Q245204', 'display_name': 'Antagonist', 'level': 3, 'score': 0.09797773}, {'id': 'https://openalex.org/C86803240', 'wikidata': 'https://www.wikidata.org/wiki/Q420', 'display_name': 'Biology', 'level': 0, 'score': 0.092428714}, {'id': 'https://openalex.org/C84393581', 'wikidata': 'https://www.wikidata.org/wiki/Q82642', 'display_name': 'Blood pressure', 'level': 2, 'score': 0.09203917}], 'mesh': [{'descriptor_ui': 'D000317', 'descriptor_name': 'Adrenergic alpha-Antagonists', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D019157', 'descriptor_name': 'Ischemic Preconditioning, Myocardial', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D011224', 'descriptor_name': 'Prazosin', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': True}, {'descriptor_ui': 'D011493', 'descriptor_name': 'Protein Kinase C', 'qualifier_ui': 'Q000037', 'qualifier_name': 'antagonists & inhibitors', 'is_major_topic': True}, {'descriptor_ui': 'D018340', 'descriptor_name': 'Receptors, Adrenergic, alpha-1', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': True}, {'descriptor_ui': 'D015398', 'descriptor_name': 'Signal Transduction', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': True}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000255', 'descriptor_name': 'Adenosine Triphosphate', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000317', 'descriptor_name': 'Adrenergic alpha-Antagonists', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000470', 'descriptor_name': 'Alkaloids', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000818', 'descriptor_name': 'Animals', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D053119', 'descriptor_name': 'Benzophenanthridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D002302', 'descriptor_name': 'Cardiac Output', 'qualifier_ui': 'Q000187', 'qualifier_name': 'drug effects', 'is_major_topic': False}, {'descriptor_ui': 'D002302', 'descriptor_name': 'Cardiac Output', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D000242', 'descriptor_name': 'Cyclic AMP', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D004734', 'descriptor_name': 'Energy Metabolism', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D006321', 'descriptor_name': 'Heart', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D066298', 'descriptor_name': 'In Vitro Techniques', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D007211', 'descriptor_name': 'Indoles', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008297', 'descriptor_name': 'Male', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D008301', 'descriptor_name': 'Maleimides', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D008301', 'descriptor_name': 'Maleimides', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D008301', 'descriptor_name': 'Maleimides', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017202', 'descriptor_name': 'Myocardial Ischemia', 'qualifier_ui': 'Q000503', 'qualifier_name': 'physiopathology', 'is_major_topic': False}, {'descriptor_ui': 'D017202', 'descriptor_name': 'Myocardial Ischemia', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D015425', 'descriptor_name': 'Myocardial Reperfusion', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D009206', 'descriptor_name': 'Myocardium', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010617', 'descriptor_name': 'Phenanthridines', 'qualifier_ui': 'Q000494', 'qualifier_name': 'pharmacology', 'is_major_topic': False}, {'descriptor_ui': 'D010617', 'descriptor_name': 'Phenanthridines', 'qualifier_ui': 'Q000008', 'qualifier_name': 'administration & dosage', 'is_major_topic': False}, {'descriptor_ui': 'D010617', 'descriptor_name': 'Phenanthridines', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D010710', 'descriptor_name': 'Phosphates', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011224', 'descriptor_name': 'Prazosin', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D011493', 'descriptor_name': 'Protein Kinase C', 'qualifier_ui': 'Q000378', 'qualifier_name': 'metabolism', 'is_major_topic': False}, {'descriptor_ui': 'D011493', 'descriptor_name': 'Protein Kinase C', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D051381', 'descriptor_name': 'Rats', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D017208', 'descriptor_name': 'Rats, Wistar', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}, {'descriptor_ui': 'D018340', 'descriptor_name': 'Receptors, Adrenergic, alpha-1', 'qualifier_ui': '', 'qualifier_name': None, 'is_major_topic': False}], 'locations_count': 2, 'locations': [{'is_oa': False, 'landing_page_url': 'https://doi.org/10.1007/bf00823590', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S131791641', 'display_name': 'Cardiovascular Drugs and Therapy', 'issn_l': '0920-3206', 'issn': ['0920-3206', '1573-7241'], 'is_oa': False, 'is_in_doaj': False, 'is_core': True, 'host_organization': 'https://openalex.org/P4310319900', 'host_organization_name': 'Springer Science+Business Media', 'host_organization_lineage': ['https://openalex.org/P4310319965', 'https://openalex.org/P4310319900'], 'host_organization_lineage_names': ['Springer Nature', 'Springer Science+Business Media'], 'type': 'journal'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}, {'is_oa': False, 'landing_page_url': 'https://pubmed.ncbi.nlm.nih.gov/8842504', 'pdf_url': None, 'source': {'id': 'https://openalex.org/S4306525036', 'display_name': 'PubMed', 'issn_l': None, 'issn': None, 'is_oa': False, 'is_in_doaj': False, 'is_core': False, 'host_organization': 'https://openalex.org/I1299303238', 'host_organization_name': 'National Institutes of Health', 'host_organization_lineage': ['https://openalex.org/I1299303238'], 'host_organization_lineage_names': ['National Institutes of Health'], 'type': 'repository'}, 'license': None, 'license_id': None, 'version': None, 'is_accepted': False, 'is_published': False}], 'best_oa_location': None, 'sustainable_development_goals': [{'score': 0.46, 'display_name': 'Zero hunger', 'id': 'https://metadata.un.org/sdg/2'}], 'grants': [], 'datasets': [], 'versions': [], 'referenced_works_count': 33, 'referenced_works': ['https://openalex.org/W1566830427', 'https://openalex.org/W1597640694', 'https://openalex.org/W1983537876', 'https://openalex.org/W1987664769', 'https://openalex.org/W1989861182', 'https://openalex.org/W1991855014', 'https://openalex.org/W2002179621', 'https://openalex.org/W2007115581', 'https://openalex.org/W2014314724', 'https://openalex.org/W2018074348', 'https://openalex.org/W2018689403', 'https://openalex.org/W2031713503', 'https://openalex.org/W2033168194', 'https://openalex.org/W2041015644', 'https://openalex.org/W2058167337', 'https://openalex.org/W2065880668', 'https://openalex.org/W2072796782', 'https://openalex.org/W2084926943', 'https://openalex.org/W2094842975', 'https://openalex.org/W2095566192', 'https://openalex.org/W2098375846', 'https://openalex.org/W2098619030', 'https://openalex.org/W2112616057', 'https://openalex.org/W2126241200', 'https://openalex.org/W2139834613', 'https://openalex.org/W2146217294', 'https://openalex.org/W2147713229', 'https://openalex.org/W2151250678', 'https://openalex.org/W2164183838', 'https://openalex.org/W2166241293', 'https://openalex.org/W2169148654', 'https://openalex.org/W8120957', 'https://openalex.org/W89646234'], 'related_works': ['https://openalex.org/W2166384296', 'https://openalex.org/W2158953691', 'https://openalex.org/W2100782721', 'https://openalex.org/W2092794654', 'https://openalex.org/W2086184661', 'https://openalex.org/W2079613256', 'https://openalex.org/W2064226629', 'https://openalex.org/W1996819183', 'https://openalex.org/W1969123769', 'https://openalex.org/W1587386936'], 'abstract_inverted_index': None, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086184661', 'counts_by_year': [{'year': 2013, 'cited_by_count': 1}], 'updated_date': '2024-12-10T23:42:29.291306', 'created_date': '2016-06-24'}