I ARC, a Novel Arachidonate-regulated, Noncapacitative Ca2+ Entry Channel

Name: Work Video:
Duration: 3 min 30 s
Olivier Mignen; Trevor J. Shuttleworth
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'suggests': [60, 248, 884], 'that': [61, 108, 118, 169, 249, 296, 306, 357, 622, 783, 808, 885, 971, 977, 1150, 1571, 1598, 1718, 1848, 2122, 2148, 2242, 2266, 2294, 2323, 2490, 2596, 2742, 3143, 3186, 3248, 3327, 3335, 3411, 3536, 3558, 3616, 3652, 3662, 3690, 3705, 3850, 3903, 4033, 4045, 4106, 4217, 4295, 4330, 4460, 4491, 4621, 4697, 4717, 4735, 4752, 4777], 'physiological': [65, 184, 253, 372, 523, 4481, 4787], 'agonist': [66, 254, 481, 660, 781], 'concentrations,': [67, 255, 661], 'where': [68, 256, 534, 3347], 'oscillatory': [69, 257, 531, 4692, 4724], 'are': [72, 260, 593, 784, 1820, 1837, 2863, 3686, 3780, 3827, 4086, 4117, 4218, 4444, 4737], 'typically': [73, 261], 'observed,': [74, 262], 'does': [75, 263], 'not': [76, 264, 897, 1703, 2151, 2281, 2460, 2547, 2612, 2926, 4224, 4640], 'conform': [77, 265], 'such': [79, 267, 496, 579, 596, 662, 1965, 3452, 3491, 4098, 4709], 'model.': [81, 269], 'Instead,': [82, 270], 'noncapacitative': [84, 272, 3145, 3399, 3715, 3875, 3908, 4205, 4630], 'Ca2+entry': [85, 273, 830, 3025, 3550, 3945], 'pathway': [86, 168, 274, 356, 928, 968, 4784], 'regulated': [87, 275], 'arachidonic': [89, 112, 277, 300, 725, 774, 801, 823, 894, 964, 1582, 1630, 2115, 3151, 3286, 3428, 3488, 3581, 3657, 3695, 3713, 3962, 4125, 4506], 'acid': [90, 113, 278, 301, 726, 775, 802, 824, 895, 1467, 1583, 2116, 3152, 3287, 3429, 3489, 3582, 3658, 3696, 3963, 4126, 4507], 'appears': [91, 279, 645], 'responsible': [94, 282, 649, 708, 2664], 'for': [95, 283, 548, 650, 709, 1060, 1285, 1332, 1370, 1418, 1578, 1783, 1792, 2665, 2868, 2915, 3566, 3710, 3793, 4700, 4797, 4815, 4830], 'under': [98, 286, 717, 1093, 2555], 'these': [99, 287, 718, 1434, 1499, 1835, 1942, 2243, 2439, 2560, 2649, 3225, 3823, 4107, 4211, 4331, 4442], 'conditions.': [100, 288], 'Using': [101, 289, 949], 'whole-cell': [102, 290, 950, 1272, 1525, 2260], 'patch': [103, 291, 951, 1169, 1176], 'clamp': [104, 292, 952, 1170, 1177], 'techniques': [105, 293, 953, 1178], 'we': [106, 294, 612, 954, 3139, 3203, 3421, 3923, 4449], 'demonstrate': [107, 295, 970, 1717], 'low': [109, 297, 659, 797, 3691], 'concentrations': [110, 298, 482, 524, 782, 798, 3692], 'activate': [114, 302, 433, 1522, 3697, 4760], 'Ca2+-selective': [116, 304], 'current': [117, 125, 305, 313, 387, 389, 392, 959, 988, 1057, 1517, 1528, 1537, 1541, 1575, 1597, 1632, 1644, 1663, 1723, 1749, 1826, 1830, 1847, 1859, 2121, 2137, 2161, 2170, 2193, 2199, 2219, 2232, 2249, 2254, 2265, 2470, 2503, 2536, 2728, 3197, 3247, 3330, 3437, 3461, 3504, 3587, 3604, 3644, 3668, 3707, 3770], 'superficially': [120, 308], 'similar': [121, 309, 1839, 2864, 3813, 4114], 'store-operated': [124, 312, 376, 388, 416, 466, 927, 985, 1536, 1846, 1962, 2565, 2619, 2630, 2996, 3196, 3246, 3436, 3480, 3549, 3769, 4096], 'I': [126, 146, 161, 314, 334, 349, 1058, 1277, 1948, 2104, 2307, 2543, 2545, 2790, 2823, 2869, 2916, 2942, 2951, 2982, 3117, 3676, 3682, 3702, 3771, 3832, 3835, 4090, 4476, 4484, 4778], 'CRAC,': [127, 315, 982, 1949, 2544], 'but': [128, 316, 4645], 'which': [129, 317, 419, 463, 644, 890, 3211, 3433, 3473], 'also': [130, 318, 2060, 2310], 'demonstrates': [131, 319], 'certain': [132, 320, 974, 3535, 4120], 'distinct': [133, 321, 922, 2989, 3333, 3406, 3915], 'features.': [134, 322], 'We': [135, 323, 1052, 2094, 2626, 3688, 3940, 4789], 'have': [136, 157, 324, 345, 613, 955, 1053, 2571, 3140, 4215, 4450], 'named': [137, 325, 1054], 'this': [138, 326, 771, 886, 962, 1055, 1313, 1368, 1566, 1572, 2247, 2421, 2597, 2908, 3187, 3570, 3706, 3920, 4549, 4622, 4636], 'novel': [139, 165, 327, 353, 616, 963, 1056, 3699], 'currentI': [140, 328], 'ARC': [141, 147, 162, 329, 335, 350, 1278, 1952, 2305, 2610, 2917, 2980, 3301, 3594, 3620, 3762, 3806, 3837, 3860, 4091, 4779], '(forarachidonate-regulated': [142, 330], 'calcium': [143, 331, 380, 391, 395, 1857], 'current).': [144, 332], 'Importantly,': [145, 333], 'can': [148, 336, 4300], 'readily': [150, 338], 'activated': [151, 175, 182, 339, 363, 370, 892, 2954, 3149, 3336, 3442, 3670, 3960, 4048, 4118, 4220, 4302], 'in': [152, 340, 408, 418, 474, 530, 666, 790, 1096, 1111, 1523, 1590, 1619, 1758, 1765, 1794, 1864, 2062, 2172, 2194, 2201, 2221, 2273, 2456, 2465, 2500, 2535, 2539, 2559, 2634, 2723, 2793, 2817, 2934, 2940, 3000, 3013, 3026, 3119, 3157, 3208, 3210, 3282, 3432, 3455, 3494, 3498, 3562, 3621, 3641, 3719, 3950, 3954, 4039, 4550, 4564, 4577, 4582, 4703, 4747, 4770], 'cells': [153, 341, 410, 1069, 1090, 1622, 1728, 1871, 2492, 2528, 2570, 2797, 2875, 3029, 3092, 3121, 3209, 3283, 3431, 3492, 3557, 3639, 3723, 4557, 4585, 4705, 4736, 4804], 'whose': [154, 342], 'been': [158, 346, 1850, 2311, 2573, 3020, 3441, 3541, 3560, 4004, 4151, 4489, 4756], 'maximally': [159, 347, 3542], 'depleted.': [160, 348], 'represents': [163, 351, 4780], 'entirely': [171, 359, 810, 921, 1954, 2988, 3332, 3405, 3914, 4500], 'separate': [172, 360], 'from': [173, 361, 923, 1082, 1204, 1226, 1367, 1433, 1470, 1476, 1489, 2250, 2444, 2525, 2911, 3229, 3278, 3334, 4031, 4089, 4094, 4558], 'those': [174, 362, 587, 664, 1841, 2747, 2866], 'store': [177, 365, 626, 813, 1957, 3338, 4226, 4236, 4643, 4689, 4701], 'depletion': [178, 366, 627, 3866, 4237, 4690], 'and': [179, 367, 430, 483, 643, 815, 826, 969, 1106, 1118, 1254, 1260, 1283, 1363, 1377, 1394, 1472, 1506, 1512, 1551, 1649, 1666, 1681, 1773, 1813, 1818, 1869, 1938, 2229, 2371, 2426, 2486, 2611, 2704, 2783, 2873, 2981, 3113, 3236, 3268, 3294, 3354, 3398, 3472, 3637, 3704, 3721, 3795, 3808, 3834, 3905, 4044, 4213, 4223, 4298, 4326, 4362, 4563, 4581, 4751, 4824, 4827], 'specifically': [181, 369, 648, 825, 3936, 4219], 'levels': [185, 373, 4731], 'stimulation.': [187, 375, 4733], 'channel(s)': [377], 'cytosolic': [378], 'free': [379, 1309], 'ion': [381], 'concentration': [382, 1311, 2686], 'farad': [383], 'release-activated': [385, 1858], 'arachidonate-regulated': [390, 1825, 3329, 3907, 4573, 4637, 4718], 'sarcoplasmic-endoplasmic': [393], 'reticulum': [394], 'pump': [396, 2961], 'N-methyl-d-glucamine': [397], 'transient': [398, 1421, 4684], 'receptor': [399, 1077, 4028], 'potential': [400, 1207, 1480, 1492, 1560, 1652, 1716, 1810, 2707], 'The': [401, 706, 1089, 1308, 1661, 2156, 2263, 2522, 2670, 2975, 3322, 3482, 3598, 4546], 'prevailing': [402], 'model': [403, 417], 'receptor-activated': [405, 4493], 'non-excitable': [409, 4017], 'or': [415, 926, 1538, 2504, 4348, 4470], 'agonist-sensitive': [424, 489], 'alone': [426], 'both': [428, 470, 3779, 3805, 4296], 'necessary': [429], 'sufficient': [431], '(1.Putney': [436, 498], 'J.W.': [437, 449, 499, 511], 'Cell': [438, 450, 500, 512, 557, 601, 4065, 4594, 4673], 'Calcium.': [439, 451, 501, 513, 558, 602, 4066, 4595, 4674], '1986;': [440, 502], '7:': [441, 503, 2021], '1-12Crossref': [442, 504], 'PubMed': [443, 455, 505, 517, 562, 606, 638, 681, 701, 740, 760, 857, 877, 915, 944, 997, 1049, 1139, 1880, 1932, 2011, 2040, 2053, 2073, 2343, 2358, 2399, 2414, 2586, 2760, 2808, 2886, 2901, 3042, 3068, 3084, 3108, 3132, 3179, 3390, 3737, 3757, 3898, 3993, 4070, 4137, 4197, 4263, 4285, 4321, 4392, 4414, 4435, 4521, 4541, 4599, 4662, 4678], 'Scopus': [444, 456, 506, 518, 563, 607, 639, 682, 702, 741, 761, 858, 878, 916, 945, 998, 1016, 1030, 1140, 1881, 1899, 1913, 1993, 2026, 2041, 2054, 2074, 2090, 2344, 2359, 2400, 2415, 2587, 2761, 2779, 2809, 2887, 2902, 3069, 3085, 3109, 3133, 3180, 3391, 3738, 3758, 3899, 3994, 4071, 4138, 4198, 4264, 4286, 4322, 4393, 4415, 4436, 4522, 4542, 4600, 4616, 4663, 4679], '(2115)': [445, 507], 'Google': [446, 458, 508, 520, 565, 609, 641, 684, 704, 743, 763, 860, 880, 918, 947, 1000, 1018, 1032, 1050, 1142, 1883, 1901, 1915, 1933, 1995, 2012, 2028, 2043, 2056, 2076, 2092, 2346, 2361, 2402, 2417, 2589, 2763, 2781, 2811, 2889, 2904, 3043, 3055, 3071, 3087, 3111, 3135, 3182, 3393, 3740, 3760, 3901, 3996, 4073, 4140, 4200, 4266, 4288, 4324, 4395, 4417, 4438, 4524, 4544, 4602, 4618, 4665, 4681], 'Scholar,': [447, 509, 685, 744, 861, 1001, 1019, 1033, 1884, 1902, 1916, 2013, 2029, 2044, 2077, 2347, 2403, 2764, 2890, 3044, 3056, 3072, 3741, 4267, 4396, 4418, 4525, 4603], '2.Putney': [448, 510], '1990;': [452, 514], '11:': [453, 515], '611-624Crossref': [454, 516], '(1264)': [457, 519], 'Scholar).': [459, 521, 566, 610, 705, 764, 881, 948, 1051, 1143, 1329, 1934, 2057, 2093, 2362, 2418, 2812, 2905, 3136, 3183, 3394, 3997, 4074, 4141, 4201, 4289, 4439, 4545, 4666], 'This': [460, 1527, 1643, 2058, 2132, 2363, 2454, 2923, 3340, 3519], 'capacitative': [461, 546, 588, 841, 925, 1406, 1420, 3024, 3352, 3397, 3574, 3904, 3938], 'entry,': [462], 'occurs': [464, 3402, 3911], 'channels': [467, 589, 2388, 2567, 2621, 3807, 3810, 4082, 4097, 4109], '(SOCs),1': [468], 'underlies': [469], 'sustained': [472], 'elevations': [473], '[Ca2+]i': [475, 532, 788, 833], 'observed': [476, 1519, 2200, 2220, 2234, 2256, 2914, 3653, 3718, 3862], 'following': [477, 656], 'stimulation': [478, 657, 3935], 'high': [480, 3791], 'subsequent': [485, 3483, 3576, 3628], 'refilling': [486, 4702], 'on': [492, 840, 1270, 1565, 1743, 1778, 1970, 2141, 2258, 3252, 3298, 3556, 4455, 4502, 4817], 'termination': [494], 'However,': [522, 1935, 2211, 4343], 'appropriate': [526], 'often': [528], 'result': [529, 2524, 4051], 'internal': [536, 1337, 2214, 2288], 'empty': [539], 'only': [540, 1774, 1788, 1845, 2572, 3291, 4208], 'partially': [541], 'and/or': [542, 2299, 4685], 'transiently': [543], 'making': [544], 'mechanism': [547, 617], 'control': [550, 4649], 'unlikely': [554, 4459], '(3.Shuttleworth': [555, 599, 4671], 'T.J.': [556, 600, 630, 669, 687, 728, 746, 845, 863, 901, 930, 1125, 3094, 3165, 3376, 3725, 3743, 3884, 3979, 4509, 4527, 4654, 4672], '1999;': [559, 603, 936, 2050, 2355, 2411, 2898, 3382, 3890, 3985, 4134, 4318, 4432, 4613, 4675], '25:': [560, 604, 4676], '237-246Crossref': [561, 605, 4677], '(94)': [564, 608, 2360, 2416, 2903, 4680], 'Furthermore,': [567, 3627], 'many': [568], 'specific': [571, 4761], 'characteristics': [572, 3477, 4077], 'seen': [577, 655, 1618, 2061, 2268, 2282, 3618], 'during': [578, 1250, 1257, 1397, 1408, 2319, 2432, 2825, 4497, 4691, 4708, 4722], 'signals,': [580], 'as': [581, 583, 663, 1121, 1321, 2285, 2945, 4049, 4668, 4765, 4767], 'well': [582, 4766], 'properties': [585, 976, 1836, 2741, 3765, 4448], 'characterized': [590, 957, 1852], 'date,': [592, 1854], 'inconsistent': [594, 4445], 'role': [598, 4482, 4634], 'Recently,': [611], 'described': [614, 1863, 2575, 2833, 2918, 4451], 'agonist-activated': [619], 'independent': [624, 811, 1955, 4234], '(i.e.noncapacitative)': [628], '(4.Shuttleworth': [629, 4653], 'Thompson': [631, 688, 747, 864, 902, 931, 1126, 3095, 3166, 3377, 3744, 3885, 3980, 4528, 4655, 4826], 'J.L.': [632, 689, 748, 865, 903, 932, 1127, 3096, 3167, 3378, 3745, 3886, 3981, 4529, 4656], 'Biochem.': [633, 3061, 4657], 'J.': [634, 670, 690, 729, 749, 846, 866, 904, 933, 1024, 1040, 1128, 1907, 1923, 1987, 2002, 2019, 2034, 2084, 2337, 2352, 2393, 2408, 2581, 2803, 2880, 2895, 3037, 3050, 3097, 3126, 3168, 3379, 3726, 3746, 3887, 3982, 4252, 4274, 4381, 4403, 4510, 4530, 4610, 4658], '1996;': [635, 673, 732, 849, 2020, 3065, 3081, 3729, 4194, 4513, 4659], '316:': [636, 4660], '819-824Crossref': [637, 4661], '(50)': [640, 4664], 'Scholar)': [642, 2782, 3902], 'resulting': [665, 2674], 'Ca2+oscillations': [667], '(5.Shuttleworth': [668, 727, 844, 3724, 4508], 'Biol.': [671, 691, 730, 750, 847, 867, 905, 934, 1041, 1129, 1924, 2003, 2354, 2410, 2897, 3098, 3128, 3169, 3380, 3727, 3747, 3888, 3983, 4253, 4275, 4382, 4404, 4511, 4531], 'Chem.': [672, 692, 731, 751, 848, 868, 906, 935, 1042, 1130, 1925, 2004, 3099, 3170, 3381, 3728, 3748, 3889, 3984, 4254, 4276, 4383, 4405, 4512, 4532], '271:': [674, 733, 850, 3730, 4514], '21720-21725Abstract': [675, 734, 851, 3731, 4515], 'Full': [676, 678, 696, 698, 735, 737, 755, 757, 852, 854, 872, 874, 910, 912, 939, 941, 1046, 1134, 1136, 1929, 2008, 2023, 3103, 3105, 3174, 3176, 3385, 3387, 3732, 3734, 3752, 3754, 3893, 3895, 3988, 3990, 4258, 4260, 4280, 4282, 4387, 4389, 4409, 4411, 4516, 4518, 4536, 4538], 'Text': [677, 679, 697, 699, 736, 738, 756, 758, 853, 855, 873, 875, 911, 913, 940, 942, 1047, 1135, 1137, 1930, 2009, 2024, 3104, 3106, 3175, 3177, 3386, 3388, 3733, 3735, 3753, 3755, 3894, 3896, 3989, 3991, 4259, 4261, 4281, 4283, 4388, 4390, 4410, 4412, 4517, 4519, 4537, 4539], 'PDF': [680, 700, 739, 759, 856, 876, 914, 943, 1048, 1138, 1931, 2010, 2025, 3107, 3178, 3389, 3736, 3756, 3897, 3992, 4262, 4284, 4391, 4413, 4520, 4540], '(144)': [683, 742, 859, 3739, 4523], '6.Shuttleworth': [686, 745, 862, 3742, 4526], '1998;': [693, 752, 869, 907, 1131, 2037, 2583, 2805, 3100, 3171, 3749, 4277, 4406, 4533], '273:': [694, 753, 870, 908, 1132, 3101, 3172, 3750, 4278, 4407, 4534], '32636-32643Abstract': [695, 754, 871, 909, 1133, 3102, 3173, 3751, 4535], '(78)': [703, 762, 879, 917, 1141, 3110, 3181, 3759, 4543], 'signal': [707], 'circumstances': [719], 'receptor-mediated': [722], 'generation': [723, 821, 4504], 'Three': [765], 'key': [766], 'pieces': [767], 'support': [770], 'contention:': [772], '1)': [773], 'same': [780, 792, 2099], 'produce': [787, 2461], 'oscillations': [789, 4498], 'cells,': [793, 1866, 2514, 3202, 3957], '2)': [794], 'addition': [795, 2111, 2957, 3426, 3484, 3577, 3629, 3655], 'exogenous': [800, 3694], 'induces': [803], 'an': [804, 1167, 2230, 2613, 2683, 3459, 3584, 3665, 4053, 4572, 4818], 'depletion,': [814, 4227], '3)': [816], 'inhibition': [817, 1699, 1815, 3238], 'agonist-induced': [820], 'rapidly': [827, 2139], 'blocks': [828], 'associated': [831, 960, 4641], 'oscillations,': [834], 'yet': [835], 'it': [836, 972, 980, 1568, 2149, 2295, 2591, 3409, 4327, 4457, 4486, 4774], 'without': [838], 'effect': [839, 1742, 1777, 3297, 3424], 'Recent': [882], 'pathway,': [889], 'itself': [896], 'metabolite': [899], '(6.Shuttleworth': [900, 1124, 3093, 3164], 'Scholar),': [919, 2590, 3088, 3112, 4325, 4619, 4682], '(7.Shuttleworth': [929, 3375, 3883, 3978], '274:': [937, 3383, 3891, 3986], '31174-31178Abstract': [938, 3384, 3892, 3987], '(86)': [946, 3392, 3900, 3995], 'now': [956], 'acid-regulated': [965], 'possesses': [973], 'unique': [975, 2607], 'clearly': [978, 2245, 2909, 3970], 'distinguish': [979, 2246], 'fromI': [981], 'archetypal': [984, 3768], 'channel': [987, 4037, 4163, 4474], '(8.Hoth': [989, 1872, 2752], 'M.': [990, 1021, 1873, 1904, 1984, 2753, 4170, 4174, 4186, 4243, 4245, 4271, 4310, 4372, 4374, 4400, 4424], 'Penner': [991, 1022, 1874, 1905, 1985, 2754], 'R.': [992, 1023, 1875, 1906, 1986, 2755, 4247, 4376], 'Nature.': [993, 1876, 2069, 2756, 4133, 4317, 4431], '1992;': [994, 1877, 2757], '355:': [995, 1878, 2758], '353-356Crossref': [996, 1879, 2759], '(1495)': [999, 1882, 2762], '9.Zweifach': [1002, 1885, 2765], 'A.': [1003, 1012, 1886, 1895, 2015, 2334, 2390, 2766, 2775, 2877, 3123, 4193], 'Lewis': [1004, 1887, 2335, 2391, 2767, 2878], 'R.S.': [1005, 1888, 2336, 2392, 2768, 2879], 'Proc.': [1006, 1889, 2769, 4187], 'Natl.': [1007, 1890, 2770, 4188], 'Acad.': [1008, 1891, 2771, 4189], 'Sci.': [1009, 1892, 2772, 4190], 'U.': [1010, 1893, 2773, 4191], 'S.': [1011, 1894, 2774, 3031, 4128, 4192, 4589], '1993;': [1013, 1027, 1043, 1896, 1910, 1926, 1990, 2005, 2776], '90:': [1014, 1897, 2777], '6259-6299Crossref': [1015, 1898, 2778], '(697)': [1017, 1900, 2780], '10.Hoth': [1020, 1903], 'Physiol.': [1025, 1908, 1988, 2036, 2085, 2339, 2395, 2582, 2804, 2882, 3038, 3051, 4611], '(Lond.).': [1026, 1909, 1989, 2086, 4612], '465:': [1028, 1911, 1991], '359-386Crossref': [1029, 1912, 1992], '(662)': [1031, 1914, 1994], '11.McDonald': [1034, 1917], 'T.V.': [1035, 1918, 1997], 'Premack': [1036, 1919, 1998], 'B.A.': [1037, 1920, 1999], 'Gardner': [1038, 1921, 2000], 'P.': [1039, 1922, 2001, 2066, 4130], '268:': [1044, 1927, 2006], '3889-3896Abstract': [1045, 1928, 2007], 'ARC,': [1059, 2424, 3685, 3703, 4485], 'rachidonate-': [1062], 'r': [1063], 'egulated': [1064], 'c': [1065], 'alcium': [1066], 'current.': [1067, 2155, 3481], 'HEK293': [1068, 2569, 2796, 4565, 4803], 'stably': [1070, 4805], 'transfected': [1071, 3361, 3930, 3956, 4806], 'human': [1074, 4809], 'm3': [1075, 4810], 'muscarinic': [1076, 4811], 'were': [1078, 1091, 1145, 1164, 1188, 1198, 1220, 1232, 1245, 1281, 1365, 1441, 1457, 1487, 1503, 1633, 2430, 2640, 2743, 2948, 3216, 3365, 3554], 'generous': [1080], 'gift': [1081], 'Dr.': [1083, 4791], 'Craig': [1084, 4792], 'Logsdon': [1085, 4793], '(University': [1086, 4794], 'Michigan).': [1088], 'cultured': [1092], 'standard': [1094, 1175, 2968], 'conditions': [1095, 2557], "Dulbecco's": [1097], 'modified': [1098], "Eagle's": [1099], 'medium': [1100], 'supplemented': [1101], '10%': [1103], 'calf': [1104], 'serum': [1105], 'antibiotics': [1107], '37': [1109], '°C': [1110], 'humidified': [1113], 'atmosphere': [1114], '95%': [1116], 'air': [1117], '5%': [1119], 'CO2': [1120], 'reported': [1122, 2367, 2749, 2867, 3142, 3926], 'previously': [1123, 2748, 3141, 3617, 4488, 4669], 'Cells': [1144], 'plated': [1146], 'onto': [1147], 'glass': [1148], 'coverslips': [1149], 'formed': [1151], 'bottom': [1153], 'perfusion': [1156], 'chamber': [1157], '(Warner)': [1158], 'immediately': [1159], 'before': [1160, 1274, 3654], 'experimentation.': [1161], 'Whole-cell': [1162, 1196], 'currents': [1163, 1197, 1396, 1407, 1437, 1456, 1502, 1713, 1944, 1964, 2429, 2488, 2631, 2675, 2699, 2792, 3207, 3414, 3526, 3783], 'recorded': [1165, 1199, 1221, 2431], 'Axopatch-1C': [1168], 'amplifier': [1171], '(Axon': [1172], 'Instruments)': [1173], 'using': [1174, 1200, 1222, 2643, 2830, 2966, 3219, 3444], 'room': [1180], 'temperature': [1181], '(20–22': [1182], '°C).': [1183], 'Patch': [1184], 'pipettes': [1185], '(Garner,': [1186], 'GC150-F)': [1187], 'fire-polished': [1189], 'resistance': [1192], '3–6': [1194], 'megaOhms.': [1195], '250-ms': [1201], 'voltage': [1202, 1224, 1252, 1258, 1485, 1637, 2321], 'steps': [1203, 1253], 'holding': [1206, 1491], '0': [1209, 1494, 2227, 4360], '−80': [1211, 1401, 1411, 1496, 1545, 1605, 1752, 2436, 2476, 2680, 2828, 3470, 3507, 3610, 3787], 'mV': [1212, 1236, 1412, 1546, 1606, 1657, 1753, 2681, 2713, 2829, 3471, 3508, 4361], 'delivered': [1213], 'every': [1214], '2': [1215, 2715, 2842, 2921], 's.': [1216], 'Alternatively,': [1217], 'current-voltage': [1218], 'relationships': [1219, 1627], '150-ms': [1223], 'ramps': [1225, 1259, 1638], '−100': [1227], '+30': [1229, 1235, 1656, 2712], 'mV.': [1230, 1402, 1497, 2437], 'Ramps': [1231], 'terminated': [1233], 'avoid': [1238], 'depolarization-activated': [1242], 'Cl−current.': [1243], 'Currents': [1244], 'sampled': [1246], '20': [1248, 2447, 2688], 'kHz': [1249, 1256], '5.5': [1255], 'digitally': [1261], 'filtered': [1262], 'off-line': [1263], '1': [1265, 1659, 1730, 2130, 2209, 2291], 'KHz.': [1266], 'Initial': [1267], 'traces': [1268], 'obtained': [1269, 1634, 2949, 2977], 'going': [1271, 2259], '(i.e.': [1273, 2517], 'orI': [1279], 'SOC)': [1280, 2633, 2677, 3199, 3439], 'averaged': [1282, 1599], 'used': [1284, 2558, 2939, 3366, 3924], 'leak': [1286, 1641, 2154], 'subtraction.': [1287], 'Internal': [1288], 'solutions': [1289, 1340, 1376, 1760, 2203, 2272], 'contained': [1290, 1341], '(in': [1291, 1342], 'mm):': [1292, 1343], 'Cs+': [1293, 2300], 'acetate,': [1294], '140;': [1295, 1345], 'NaCl,': [1296, 1344], '10;': [1297, 1349, 1353], 'MgCl2,': [1298, 1346], '1.22;': [1299], 'CaCl2,': [1300, 1348], '1.89;': [1301], 'EGTA,': [1302], '5;': [1303, 1351], 'HEPES,': [1304, 1354], '10': [1305, 1355, 2445], '(pH': [1306, 1356], '7.2).': [1307], 'solution': [1314, 1369, 2224, 2938, 2970], 'was': [1315, 1382, 1389, 1468, 1518, 1529, 1576, 1617, 1664, 2101, 2123, 2138, 2162, 2520, 2592, 2604, 2690, 2953, 3191, 3249, 3612, 4328], 'calculated': [1316], '100': [1319, 2972], 'nm': [1320, 2973], 'computed': [1322], 'Maxchelator': [1324], '(12.$$$$$$': [1325], 'ref': [1326], 'data': [1327, 1702, 2947, 2976, 3324, 3878], 'missingGoogle': [1328], 'CaCl2was': [1330], 'omitted': [1331, 1366], 'experiments': [1334, 1372, 1614, 2944, 3553], 'involving': [1335, 1373], 'Ca2+-free': [1336, 2645, 3221, 3446], 'solutions.': [1338], 'Extracellular': [1339], '1.2;': [1347], 'CsCl,': [1350], 'd-glucose,': [1352], '7.4)': [1357], 'unless': [1358], 'otherwise': [1359], 'specified.': [1360], 'Both': [1361], 'MgCl2': [1362], 'CaCl2': [1364], 'divalent-free': [1374, 2108, 2202, 2222], 'external': [1375, 1798, 2684], 'osmolarity': [1379], '(320': [1380], 'mosmol/liter)': [1381], 'maintained': [1383], 'additional': [1385, 2992, 3552, 3585, 3602, 3666], 'd-glucose.': [1386], 'Fast': [1387], 'inactivation/activation': [1388], 'examined': [1390, 2096, 2628, 3205], 'comparing': [1392], 'peak': [1393, 1436, 2425, 2485], 'steady-state': [1395, 2427, 2468, 2487], 'hyperpolarizing': [1398, 1453, 1484, 2320, 2433], 'pulses': [1399, 1409, 1486, 2322, 2434, 2826], 'Examination': [1403, 2813], 'indicated': [1413], 'mean': [1415, 1708, 2523], 'time': [1416, 2327, 2851], 'constant': [1417, 2328, 2852], '240': [1423], '±': [1424, 1601, 1755, 1762, 2180, 2187, 2472, 2532, 2692, 2847, 2855, 3240, 3261, 3311, 3606], '7.6': [1425], 'μs': [1426], '(n': [1427, 1607, 1623, 2695, 2858, 3313], '=': [1428, 1608, 1624, 1768, 2183, 2479, 2696, 2859, 3242, 3314], '159).': [1429], 'To': [1430, 1478, 2419, 3184, 3418, 3533], 'minimize': [1431], 'contributions': [1432], 'transients,': [1435], '(1': [1438, 2964, 3564], 'ms': [1439, 1447, 1464, 2332, 2857], 'average)': [1440], 'determined': [1442, 1459], 'point': [1445, 1462], '3': [1446, 3303, 3320], 'after': [1448, 1639, 3864], 'start': [1450], 'pulse.': [1454], 'Steady-state': [1455], 'similarly': [1458], '200': [1463, 3317], 'later.': [1465], 'Arachidonic': [1466], 'purchased': [1469], 'BioMol': [1471], 'all': [1473, 1613, 1821, 2526, 3475], 'other': [1474], 'chemicals': [1475], 'Sigma.': [1477], 'observe': [1479], 'currents,': [1483, 3681, 4354], 'applied': [1488], 'Under': [1498, 2648, 3224], 'conditions,': [1500, 2650, 3226], 'basal': [1501], 'usually': [1504], 'small': [1505, 1595, 3293, 3781], 'variable': [1507], '(typically': [1508], 'ranging': [1509], 'between': [1510, 1727, 1941, 3369, 3831, 3972], '+0.2': [1511], '−0.3': [1513], 'pA/pF).': [1514, 2189], '2Occasionally,': [1515], 'spontaneously': [1521, 1573], 'mode.': [1526], 'much': [1530, 4001], 'larger': [1531, 2165], 'than': [1532, 1655, 2166, 2711, 3651], 'either': [1533, 2496, 4346], 'endogenous': [1535, 2564, 2618, 3195, 3435, 3548, 4080], 'arachidonate-activated': [1540, 1712, 1785, 2428, 2469, 3355, 3603], '(∼1.8': [1542], 'pA/pF': [1543, 1603, 1757, 1764, 2474, 2694, 3468, 3516, 3608, 3785], 'compared': [1547], '∼0.6': [1549], 'pA/pF),': [1550], 'demonstrated': [1552, 1842, 2312, 2740, 3192], 'linear': [1554], 'I/V': [1555, 1781], 'curve': [1556, 1782], 'reversal': [1559, 1651, 1809, 2706, 4356], 'close': [1561, 4358], 'zero.': [1563], 'Based': [1564, 4454], 'would': [1569], 'appear': [1570], 'nonselective': [1577, 2253, 4352], 'cations.': [1579], 'Addition': [1580, 1683], '(8': [1584, 3288], 'μm)': [1585, 2128, 2965, 3289, 3565, 3633], 'bath': [1588], 'resulted': [1589, 2722, 3454, 3493, 3640], 'inward': [1596, 1647, 1748, 1805, 2120, 2206, 2702, 3460, 3503, 3586, 3797], '0.56': [1600, 2186], '0.05': [1602, 1756, 2188], '10)': [1609], '(Fig.1': [1610], 'A).': [1611, 2509, 2922, 3518], 'Taking': [1612], 'together,': [1615], '76%': [1620], '120).': [1625], 'Current-voltage': [1626], 'acid-activated': [1631], 'applying': [1636], 'subtracting': [1640], 'currents.': [1642], 'shows': [1645, 2204, 3838], 'strong': [1646, 1804], 'rectification': [1648, 2207, 2703], 'more': [1653, 2709], 'positive': [1654, 1808, 2236, 2710], '(Fig.': [1658, 1678, 1729, 2129, 2208, 2290, 2714, 2841, 2920, 3302, 3319, 3595], 'B).': [1660, 1682, 2716, 3597], 'arachidonate-induced': [1662], 'fully': [1665, 3545], 'reversibly': [1667], 'inhibited': [1668, 2124], '50': [1670, 1685], 'μm': [1671, 1686, 2114, 3487, 3580], 'La3+,': [1672], 'potent': [1674, 1814], 'blocker': [1675, 1689], 'Ca2+influx': [1677], '1,': [1679], 'A': [1680, 3267, 4290], 'Cd2+,': [1687], 'another': [1688], 'Ca2+influx,': [1691], 'produced': [1692, 3233, 3946], 'similar,': [1694], 'although': [1695], 'somewhat': [1696], 'less': [1697], 'complete,': [1698], '(approximately': [1700], '85%;': [1701], 'shown).': [1704, 2734], 'Plots': [1705], 'amplitude': [1709], 'against': [1714], 'membrane': [1715, 3407, 3917], 'magnitude': [1720, 1745, 2157, 2671, 2819, 3464, 3500, 3599, 3782], 'reasonably': [1725], 'consistent': [1726, 1822, 2550, 2745, 2838, 3342, 3522], 'C).': [1731, 3269, 3321], 'Complete': [1732], 'substitution': [1733], 'extracellular': [1735, 1973, 2109, 2144, 2176, 2223, 2277, 2441, 2457, 2719, 2956, 3014, 3158, 3276, 3777, 3802, 3848], 'Na+': [1736, 1759, 1793, 2298], 'NMDG+': [1738, 1766, 2284], 'had': [1739, 3290, 3440, 3540, 3559], 'no': [1740, 2497], 'significant': [1741, 2463, 2498, 2516, 2601], 'measured': [1750, 2171, 2467, 2484, 2502, 2678, 3505], '(0.57': [1754], 'versus0.49': [1761], '0.03': [1763], 'solutions,n': [1767], '4,': [1769], 'p': [1770], '<': [1771], '0.05)': [1772], 'minor': [1776], 'overall': [1780, 3643], 'current,': [1786, 3701], 'indicating': [1787, 2293, 2537], 'minimal': [1790], 'permeability': [1791], 'presence': [1796, 2174, 3775], 'Ca2+.': [1799, 2974], 'This,': [1800], 'together': [1801], 'rectification,': [1806], 'very': [1807, 1838, 4087, 4552], '(>+30': [1811], 'mV),': [1812, 3788], 'La3+': [1817, 2126, 3631, 3663], 'Cd2+': [1819], 'being': [1827, 3531, 4232], '(=I': [1831], 'ARC).': [1832], 'As': [1833, 2562, 2735, 2906, 3449, 4478], 'such,': [1834, 2736, 2907], 'has': [1849, 2309, 3019, 4003, 4021, 4104, 4150, 4293, 4487, 4755], 'extensively': [1851], 'namely': [1855], '(I': [1860, 2632, 3198, 3438, 3527], 'CRAC)': [1861], 'originally': [1862], 'mast': [1865], 'T': [1867, 2871], 'lymphocytes,': [1868], 'RBL': [1870, 2874, 3120], 'clear': [1937, 4776], 'distinction': [1940], 'two': [1943, 3371, 3404, 3413, 3525, 3680, 3913, 3974, 4209, 4551], 'that,': [1946, 1969, 2538, 3942], 'unlike': [1947], 'ofI': [1951, 2609, 3593, 3853, 3859], 'depletion.': [1958, 3339], 'Another': [1959], 'feature': [1960, 2608, 2994], 'asI': [1966, 4099], 'CRAC': [1967, 2308, 2387, 2751, 3118, 3809, 3833], 'removal': [1971, 3800], 'divalent': [1974, 2145, 2177, 2278, 2720, 3803], 'cations,': [1975], 'they': [1976], 'become': [1977, 2654], 'highly': [1978, 2837], 'permeable': [1979, 3818], 'monovalent': [1981, 2136, 2160, 2198, 2218, 2248, 2731, 3820], 'ions': [1982, 2178, 2732], '(10.Hoth': [1983], 'Scholar,11.McDonald': [1996], '13.Lepple-Wienhues': [2014], 'Cahalan': [2016, 2032, 2047], 'M.D.': [2017, 2033, 2048], 'Biophys.': [2018, 3062], '787-794Abstract': [2022], '(119)': [2027], '14.Kerschbaum': [2030], 'H.H.': [2031, 2046], 'Gen.': [2035, 2338, 2394, 2881], '111:': [2038], '521-537Crossref': [2039], '(85)': [2042], '15.Kerschbaum': [2045], 'Science.': [2049], '283:': [2051], '836-839Crossref': [2052], '(129)': [2055], 'voltage-activated': [2063], 'Ca2+currents': [2064], '(16.Hess': [2065], 'Tsien': [2067], 'R.W.': [2068], '1984;': [2070, 2087], '309:': [2071], '453-456Crossref': [2072], '(580)': [2075], '17.Almers': [2078], 'W.': [2079], 'McCleskey': [2080], 'E.W.': [2081], 'Palade': [2082], 'P.T.': [2083], '353:': [2088], '565-583Crossref': [2089], '(212)': [2091], 'therefore': [2095, 2627], 'whether': [2097], 'phenomenon': [2100, 2422], 'shown': [2102, 3021, 4105, 4152, 4294, 4490, 4757], 'ARC.': [2105, 4453, 4477], 'In': [2106, 2438, 2510, 3137, 3270, 3773, 3919, 3998], 'nominally': [2107], 'solutions,': [2110, 2216], '8': [2113, 3486, 3579], 'elicited': [2117], 'large': [2119, 2727, 4364], '(50': [2127, 3632], 'D).': [2131], 'reversed': [2140, 3251], 'restoration': [2142, 3253], 'ions,': [2146, 3804], 'demonstrating': [2147, 3873], 'approximately': [2163, 2330, 3466, 3514], '50-fold': [2164], 'normal': [2168, 2195, 3256], '(27.6': [2179], '1.7': [2181], 'pA/pF,n': [2182], '11': [2184, 2527], 'versus': [2185], 'Like': [2190], 'medium,': [2196], 'marked': [2205, 2540, 2701, 3009, 3271, 3796, 3845], 'E).': [2210], 'Na+-containing': [2213, 2270], '(pipette)': [2215, 2937], 'reverses': [2225], 'near': [2226, 2382], 'mV,': [2228, 2477], 'outward': [2231, 2264], 'potentials.': [2237], 'It': [2238], 'should': [2239, 3415], 'noted': [2241, 3450], 'features': [2244, 3825, 4443], 'spontaneous': [2252], 'sometimes': [2255], 'initially': [2257], '(see': [2261], 'above).': [2262], 'pipette': [2271, 2646, 2969, 3222, 3447], 'absence': [2275, 2931, 3623], 'cations': [2279, 2721], 'main': [2287], 'cation': [2289, 4341, 4353], 'E),': [2292], 'likely': [2296, 3708], 'reflects': [2297], 'moving': [2301], 'outwards': [2302], 'through': [2303, 3403, 3912], 'channels.': [2306, 2990, 4342], 'display': [2314], 'pronounced': [2316, 3237], 'fast': [2317, 2364, 2551, 2602, 2839, 3841], 'inactivation': [2318, 2365, 2519, 2603, 2840], 'operates': [2324], '10–30': [2331], '(18.Zweifach': [2333, 2389, 2876], '1995;': [2340, 2396, 2883, 3052, 3129, 4067], '105:': [2341, 2397, 2884], '209-226Crossref': [2342, 2398, 2885], '(336)': [2345, 2401, 2888], '19.Fierro': [2348, 2404, 2891], 'L.': [2349, 2405, 2892, 4166, 4251, 4273, 4380, 4402, 4587], 'Parekh': [2350, 2406, 2893], 'A.B.': [2351, 2407, 2894], 'Membr.': [2353, 2409, 2896, 3127], '168:': [2356, 2412, 2899], '9-17Crossref': [2357, 2413, 2900], 'Ca2+-dependent': [2370, 2452], 'reflect': [2373, 2984], 'feedback': [2375], 'process': [2376], 'driven': [2377], 'local': [2379], 'domains': [2381], 'mouth': [2384], 'examine': [2420, 3419], 'inI': [2423], 'experiments,': [2440], 'Ca2+was': [2442], 'raised': [2443], 'mm': [2448, 2689], 'maximize': [2450], 'any': [2451, 2462, 2549, 2600, 4461], 'inactivation.': [2453], 'increase': [2455, 2464, 2507, 2534, 3497, 3949], 'did': [2459], '(0.58': [2471], '0.06': [2473, 2693, 3607], 'n': [2478], '9).': [2480], 'Comparison': [2481], 'revealed': [2489, 2835], 'most': [2491, 4704], 'studied': [2493], '(8/11)': [2494], 'showed': [2495, 2529, 2700, 3474, 3941], 'change': [2499, 2816], 'slight': [2506], '(Fig.2': [2508], 'remaining': [2512], 'three': [2513], '>10%)': [2518], 'recorded.': [2521], '10.7': [2531], '10.9%': [2533], 'contrast': [2541], 'ARCdoes': [2546], 'show': [2548], 'inactivation,': [2552, 3842], 'least': [2554], 'experiments.': [2561], 'briefly': [2574], '(20.Fasolato': [2576, 2798], 'Nilius': [2578, 2800], 'B.': [2579, 2801, 4176], 'Eur.': [2580, 2802], '436:': [2584, 2806], '69-74Crossref': [2585, 2807], '(96)': [2588, 2810], 'important': [2593], 'confirm': [2595, 3185, 3879], 'lack': [2598], 'genuinely': [2605], 'unusual': [2614], 'property': [2615], 'm3-HEK': [2624, 2636, 2822, 3091, 3201], 'cells.': [2625, 2637, 4018], 'Intracellular': [2638], 'depleted': [2641, 2655, 3217], 'solution.': [2647, 3223, 3448], 'passively': [2653], 'due': [2656], 'inability': [2659], 'SERCA': [2662, 2960], 'pumps': [2663], 'replenishing': [2666], 'them': [2667], 'operate.': [2669], '(m3-HEKI': [2676], '0.60': [2691], '10).': [2697, 2860], 'These': [2698, 2861, 3877, 4711], 'significantly': [2708, 3649], 'Removal': [2717], 'appearance': [2725], 'carried': [2729], '(not': [2733], 'm3-HEKI': [2738], 'SOC': [2739, 2824, 2943, 2952, 2983, 3528, 3683], 'broadly': [2744], 'forI': [2750, 3619, 4452], 'earlier': [2786, 3345, 3881, 3921], 'brief': [2787], 'description': [2788], 'CRAC-like': [2791], 'parental': [2795], 'protocol': [2832], 'above': [2834, 2919, 3323], 'C)': [2843], 'amounting': [2844, 3305], '25.5': [2846], '2.1%': [2848], '41.8': [2854], '2.5': [2856], 'values': [2862], 'CRACin': [2870], 'lymphocytes': [2872], 'differs': [2910], 'response': [2913], 'difference': [2924], 'could': [2925], 'explained': [2928], 'identical': [2946, 3614], 'if': [2950, 3396], 'inhibitor': [2962], 'thapsigargin': [2963, 3563, 3625, 3673], 'containing': [2971], 'suggest': [2978, 3326], 'thatI': [2979], 'activity': [2986, 3953], 'An': [2991], 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[3678], 'conclude': [3689, 4716], 'accounts': [3709], 'receptor-activated,': [3712], 'acid-dependent,': [3714], 'these,': [3720], 'other,': [3722], 'Scholar).I': [3761], 'shares': [3763], 'some': [3764, 3828], 'CRAC.': [3772, 3854], '(∼0.5–1.0': [3784], 'selectivity': [3792], 'rectification.': [3798], 'Upon': [3799], 'exhibit': [3811], 'loss': [3814], 'selectivity,': [3816], 'becoming': [3817], 'ions.': [3821], 'shared': [3824], 'there': [3826], 'striking': [3829], 'differences': [3830], 'ARC.I': [3836], 'neither': [3839], 'nor': [3843], 'characteristic': [3852], 'Most': [3855], 'importantly,': [3856], 'even': [3863], 'stores,': [3871], 'its': [3874, 4629], 'nature.': [3876], 'proposal': [3882], 'ionic': [3916], 'conductances.': [3918], 'study': [3922], 'Ca2+entry.': [3939], 'while': [3943], 'thapsigargin-activated': [3944], 'profound': [3948], 'completely': [3964], 'failed': [3965], 'do': [3967], 'so': [3968], 'discriminating': [3971], 'years': [4000], 'effort': [4002], 'made': 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[4305], 'T.': [4306, 4314, 4420, 4428], 'Obukhov': [4307, 4421], 'A.G.': [4308, 4422], 'Schaefer': [4309, 4423], 'Harteneck': [4311, 4425], 'Gudermann': [4313, 4427], 'Schultz': [4315, 4429], '259-263Crossref': [4320, 4434], '(1268)': [4323, 4437], 'suggested': [4329], 'represent': [4333, 4472], 'members': [4334], 'new': [4337], 'class': [4338], 'nonstore-operated': [4340], 'expression': [4344], 'characteristically': [4350], 'produces': [4351], 'potentials': [4357], 'unitary': [4365], 'conductances': [4366], '31.Hofmann': [4419], 'All': [4440], 'seems': [4458], 'currently': [4464], 'TRPs': [4467], '(including': [4468], 'TRP3)': [4471], 'underlying': [4475], 'dependent': [4501], 'demonstration': [4547], '(exocrine': [4556], 'avian': [4560], 'nasal': [4561], 'gland': [4562], 'along': [4567], 'reports': [4570], 'Balb/c': [4578], '3T3': [4579], 'fibroblasts': [4580], 'smooth': [4583], 'muscle': [4584], '(32.Munaron': [4586], 'Antoiotti': [4588], 'Distasi': [4590], 'Lovisolo': [4592], '22:': [4597], '179-188Crossref': [4598], '(62)': [4601], '33.Broad': [4604], 'L.M.': [4605], 'Cannon': [4606], 'T.R.': [4607], 'Taylor': [4608], 'C.W.': [4609], '517:': [4614], '121-134Crossref': [4615], '(196)': [4617], 'indicates': [4620], 'widespread': [4625], 'phenomenon.': [4626], 'Consistent': [4627], 'nature,': [4631], 'refilling,': [4644], 'rather': [4646], 'oscillation': [4651, 4753], 'frequency': [4652, 4749, 4754], 'Indeed,': [4667], 'argued': [4670], 'partial': [4686], 'probably': [4695], 'means': [4696], 'requirement': [4699], 'limited': [4707], 'responses.': [4710], 'considerations': [4712], 'us': [4714, 4800], 'predominates': [4721], 'responses': [4726], 'typical': [4727], 'physiologically': [4729], 'relevant': [4730], 'Given': [4734], 'particularly': [4741], 'responsive': [4742], 'varying': [4746], 'domain': [4750], 'selectively': [4759], 'kinases,': [4762], 'transcription': [4763], 'factors,': [4764], 'mitochondrial': [4768], 'metabolism': [4769], 'frequency-dependent': [4772], 'manner,': [4773], 'significance.': [4788], 'thank': [4790], 'Michigan)': [4796], 'generously': [4798], 'providing': [4799], 'receptor,': [4812], 'Ted': [4813], 'Begenisich': [4814], 'comments': [4816], 'early': [4819], 'version': [4820], 'manuscript,': [4823], 'Jill': [4825], 'Erin': [4828], 'McNeil-Szostak': [4829], 'technical': [4831], 'assistance.': [4832]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086076030', 'counts_by_year': [{'year': 2023, 'cited_by_count': 4}, {'year': 2022, 'cited_by_count': 4}, {'year': 2020, 'cited_by_count': 4}, {'year': 2019, 'cited_by_count': 3}, {'year': 2018, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 7}, {'year': 2015, 'cited_by_count': 5}, {'year': 2014, 'cited_by_count': 7}, {'year': 2013, 'cited_by_count': 9}, {'year': 2012, 'cited_by_count': 7}], 'updated_date': '2024-12-13T09:54:54.012408', 'created_date': '2016-06-24'}
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