Publication Information

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1637, 1759, 1938, 1944, 1978, 1991, 2026, 2053, 2083, 2093, 2214, 2223, 2227, 2440, 2447, 2452, 2586, 2602, 2625, 2630, 2637, 2862, 2868, 3065, 3101, 3114, 3190, 3206, 3216, 3254, 3454, 3495, 3501, 3574, 3630, 3801, 3813, 3822, 3829, 3848, 3856, 3918, 4011, 4132, 4142, 4188, 4213, 4308, 4311, 4316, 4320, 4343, 4360, 4375, 4407, 4427], 'split': [2, 215, 433, 451, 461, 868, 1484], '1': [3, 216, 1490, 3590, 3909], '(Hes1)': [4, 217], 'is': [5, 44, 70, 79, 141, 218, 257, 283, 292, 354, 991, 1178, 1271, 1295, 1872, 1961, 1972, 2032, 2058, 2071, 2218, 2444, 2471, 3246, 3804, 3914, 3995], 'a': [6, 94, 133, 219, 307, 346, 538, 1179, 1185, 1272, 1403, 1634, 1752, 1757, 1950, 2072, 2090, 2445, 3214, 3252, 3492, 3571, 3642, 4302, 4408, 4422], 'mammalian': [7, 220, 467, 988, 1194, 1475, 1643, 1916, 3255, 3444, 3620], 'transcriptional': [8, 65, 83, 99, 134, 186, 221, 278, 296, 312, 347, 399, 543, 854, 1180, 1304, 1320, 1404, 1539, 1753, 1868, 1900, 1957, 2040, 2047, 2098, 2438], 'repressor': [9, 222, 1181], 'that': [10, 35, 47, 60, 78, 91, 129, 185, 199, 223, 248, 260, 273, 291, 304, 342, 398, 412, 533, 845, 1182, 1269, 1302, 1312, 1383, 1400, 1474, 1632, 1748, 1867, 1908, 1910, 1968, 2023, 2043, 2210, 2424, 3110, 3415, 3553, 3611, 3623, 3917, 3993, 4047, 4082, 4299, 4307], 'plays': [11, 61, 224, 274], 'crucial': [12, 225, 1273], 'roles': [13, 63, 226, 276, 3809], 'in': [14, 64, 227, 277, 474, 489, 553, 752, 885, 1062, 1102, 1279, 1309, 1538, 1552, 1641, 1646, 1706, 1893, 1915, 1962, 1975, 1996, 2055, 2456, 2468, 3062, 3117, 3185, 3197, 3251, 3358, 3424, 3442, 3619, 3810, 4096, 4157, 4176, 4193, 4207, 4331, 4357, 4363, 4415], 'the': [15, 32, 37, 51, 54, 58, 73, 88, 98, 106, 110, 125, 145, 152, 159, 171, 175, 195, 207, 228, 245, 250, 264, 267, 271, 286, 301, 311, 319, 323, 338, 358, 365, 372, 384, 388, 408, 420, 466, 475, 479, 499, 506, 525, 549, 592, 753, 864, 879, 882, 890, 987, 992, 1015, 1022, 1031, 1063, 1189, 1283, 1299, 1318, 1385, 1390, 1472, 1553, 1642, 1746, 1921, 1930, 1945, 1969, 1976, 1989, 2024, 2062, 2078, 2211, 2224, 2433, 2437, 2448, 2453, 2577, 2582, 2593, 2598, 2609, 2617, 2620, 2634, 2696, 3063, 3096, 3111, 3121, 3186, 3198, 3218, 3237, 3580, 3586, 3627, 3655, 3709, 3802, 3811, 3818, 3827, 3853, 4006, 4045, 4059, 4087, 4158, 4167, 4177, 4195, 4210, 4216, 4237, 4312, 4321, 4327, 4332, 4339, 4358, 4364, 4378, 4386, 4405, 4416, 4425, 4432], 'regulation': [16, 229, 1977, 3812], 'several': [18, 231, 587], 'developmental': [19, 232, 1032, 1106], 'processes,': [20, 233], 'including': [21, 234, 3923], 'neuronal': [22, 235, 507, 535, 764, 847, 874, 1060, 1095, 1277, 1651], 'differentiation.': [23, 236], 'The': [24, 237, 496, 982, 2051, 2442, 3099, 4090, 4130, 4149], 'aim': [25, 238], 'this': [27, 240, 1545, 3430, 3624, 4004, 4052, 4133], 'study': [28, 241], 'was': [29, 242, 2573, 2589, 2673, 3104, 3120, 3210, 3647, 3895, 4041, 4063, 4093, 4136, 4154, 4173, 4191, 4352, 4382, 4412], 'to': [30, 105, 158, 243, 318, 371, 491, 505, 518, 547, 591, 863, 887, 1104, 1173, 1396, 1495, 1756, 1882, 1920, 2028, 2066, 2077, 3004, 3010, 3060, 3212, 3428, 3641, 3663, 3806, 3844, 3851, 3916, 4043, 4075, 4086, 4099, 4230, 4306, 4390, 4429, 4438], 'elucidate': [31, 244], 'molecular': [33, 246, 1300], 'mechanisms': [34, 247, 497, 1301], 'regulate': [36, 249, 2436], 'transcription': [38, 115, 176, 251, 328, 389, 522, 1935, 1985, 2228, 3128, 3419, 3823], 'repression': [39, 116, 177, 187, 252, 329, 390, 400, 855, 1305, 1540, 1869, 1936, 3420], 'activity': [40, 117, 209, 253, 330, 422, 1937, 2439], 'Hes1.': [42, 137, 180, 255, 350, 393, 1542, 2050, 2441, 3498, 3631, 3857], 'It': [43, 256, 1880], 'shown': [45, 258, 4228], 'here': [46, 259], 'Hes1': [48, 75, 119, 189, 261, 288, 332, 402, 993, 1092, 1177, 1270, 1547, 1638, 1699, 1871, 1887, 1911, 1939, 2027, 2056, 2217, 2237, 2626, 3245, 3423, 3436, 3614, 3635, 3651, 3840, 3894, 3994, 4048, 4189, 4214, 4300, 4317, 4344, 4361, 4428], 'associates': [49, 262], 'with': [50, 164, 192, 263, 377, 405, 1317, 1389, 1544, 1702, 1745, 1876, 1913, 1964, 2030, 2235, 2612, 2745, 2806, 3248, 3354, 3422, 3487, 3509, 3558, 3570, 3616, 3654, 3708, 3837, 3998, 4051, 4065, 4209, 4215, 4233, 4354, 4431], 'nuclear': [52, 107, 111, 160, 196, 265, 320, 324, 373, 409, 1186, 1922, 1931, 1953, 1970, 2036, 2434, 3012, 3052, 3644, 3656, 3710, 3869, 3920, 4000, 4007, 4080, 4088, 4101, 4146, 4168, 4178, 4198, 4219, 4238, 4340, 4394, 4433], 'matrix,': [53, 266, 1923, 3657], 'ribonucleoprotein': [55, 268, 3799], 'network': [56, 269, 3800], 'nucleus': [59, 272, 3803], 'important': [62, 275, 3808], 'regulation.': [66, 279], 'Nuclear': [67, 280], 'matrix': [68, 112, 161, 197, 281, 325, 374, 410, 1932, 1954, 1971, 2037, 2435, 3013, 3711, 3921, 4008, 4102, 4147, 4169, 4179, 4199, 4239, 4341, 4434], 'binding': [69, 95, 282, 308, 439, 1955, 4314], 'mediated': [71, 284], 'by': [72, 122, 144, 188, 285, 335, 357, 401, 511, 876, 1306, 1541, 1650, 1870, 1874, 1942, 1981, 2061, 2221, 2575, 2591, 2607, 2676, 3018, 3056, 3236, 3816, 3900, 4072, 4138, 4318], 'same': [74, 287, 1946, 3122], 'C-terminal': [76, 289, 1947, 4409], 'domain': [77, 86, 290, 299, 440], 'also': [80, 103, 293, 316, 1927, 2021, 3706, 4383], 'required': [81, 294, 2033], 'for': [82, 97, 136, 295, 310, 349, 1406, 2034, 2049, 2216, 3220, 3233, 3242, 3491], 'repression.': [84, 297, 1958], 'This': [85, 138, 298, 351, 1959, 3797, 3912, 4350, 4400], 'contains': [87, 300], 'WRPW': [89, 126, 302, 339, 3587, 3628, 4328], 'motif': [90, 303, 3588, 3629, 4329], 'acts': [92, 131, 305, 344, 1183, 1402], 'as': [93, 132, 203, 306, 345, 416, 548, 1184, 1480, 1496, 2046, 2067, 2089, 2700, 2740, 2752, 2908, 3016, 3069, 3132, 3226, 3873], 'site': [96, 309, 2585, 2601, 2636], 'corepressor': [100, 135, 139, 313, 348, 352, 1405, 1754, 2099, 2212], 'Groucho,': [101, 314], 'which': [102, 156, 315, 369, 852, 871, 2230, 3450, 3578], 'localizes': [104, 157, 317, 370, 1919], 'matrix.': [108, 321, 4089], 'Both': [109, 322, 1929], 'association': [113, 326, 1933, 2038, 4212, 4342], 'and': [114, 162, 166, 174, 198, 327, 375, 379, 387, 411, 448, 484, 493, 571, 596, 1025, 1097, 1281, 1548, 1630, 1704, 1888, 1918, 1934, 1956, 1983, 2039, 2085, 2233, 2238, 2429, 2450, 2464, 2483, 2614, 2693, 2736, 2742, 3007, 3050, 3230, 3351, 3356, 3437, 3497, 3576, 3595, 3606, 3613, 3622, 3636, 3820, 3841, 3864, 3867, 3910, 3991, 4058, 4068, 4079, 4145, 4197, 4205, 4236, 4393, 4435], 'are': [120, 333, 509, 861, 1291, 1550, 1902, 1926, 1940, 2231, 3661, 4083], 'inhibited': [121, 334, 1941], 'deletion': [123, 336, 1943], 'motif,': [127, 340], 'indicating': [128, 341, 1949, 2042], 'Groucho': [130, 165, 193, 343, 378, 406, 1322, 1401], 'role': [140, 353, 2213], 'not': [142, 355, 2059, 3568, 4084], 'modulated': [143, 356], 'Groucho-related': [146, 359, 443, 1487], 'gene': [147, 360, 444, 994, 1979, 3814], 'product': [148, 361, 2580, 2596, 4406], 'Grg5.': [149, 362], 'In': [150, 363, 465, 1014, 1697, 2205, 3201, 3564, 3858], 'contrast,': [151, 364, 2206, 3565], 'Runt-related': [153, 366], 'protein': [154, 367, 3494, 3573, 4334], 'RUNX2,': [155, 368], 'interacts': [163, 376, 1701, 1912, 3353], 'Hes1,': [167, 380, 1307, 2427], 'can': [168, 381], 'inhibit': [169, 382, 1384], 'both': [170, 383, 2035, 2236, 4194, 4234], 'Groucho·Hes1': [172, 211, 385, 424], 'interaction': [173, 386, 1387, 3625, 3821], 'ability': [178, 391, 1391, 2025, 4315, 4426, 4437], 'Together,': [181, 394, 1265], 'these': [182, 395, 502, 1266, 1407, 1864, 2421, 2457, 4296], 'observations': [183, 396, 1865], 'suggest': [184, 397, 1866, 2209, 2423, 3414], 'requires': [190, 403, 3626], 'interactions': [191, 404, 1875, 2425], 'at': [194, 407, 2094, 2432, 3599], 'RUNX': [200, 413, 2225, 2430, 3703, 3924], 'proteins': [201, 414, 551, 750, 851, 1315, 1395, 1750, 1890, 2240, 2431, 3014, 3250, 3439, 3556, 3638, 3660, 4055, 4081, 4103, 4225], 'act': [202, 415, 2045], 'negative': [204, 417, 515, 1274], 'regulators': [205, 418, 516], 'repressive': [208, 421], 'complexes.': [212, 425], 'basic': [426, 526], 'helix': [427, 429, 527, 529], 'loop': [428, 528], 'amino-terminal': [430, 4379], 'Enhancer': [431, 449, 459, 1482], 'achaete-scute': [434], 'homolog': [435, 437], 'atonal': [436], 'DNA': [438, 2611, 3102, 3115, 3209], 'GAL4': [442], 'glutathione': [445], 'S-transferase': [446], 'Hairy': [447], 'polyacrylamide': [452], 'gel': [453], 'electrophoresis': [454], 'polymerase': [455], 'chain': [456], 'reaction': [457], 'transducin-like': [458, 1481], 'WD40': [462], 'repeat': [463], 'kilobase(s)': [464], 'central': [468], 'nervous': [469, 1016, 1554], 'system,': [470, 1017], 'progenitor': [471, 503], 'cells': [472, 504, 1917, 2690, 3001, 3092, 3621, 3834], 'located': [473], 'ventricular': [476], 'zone': [477], 'neural': [480], 'tube': [481], 'undergo': [482], 'proliferation': [483], 'ultimately': [485], 'differentiate': [486], 'into': [487, 2581, 2597, 2633], 'neurons': [488, 1036], 'response': [490, 886], 'intrinsic': [492], 'extrinsic': [494], 'cues.': [495], 'regulating': [498, 878], 'commitment': [500], 'fate': [508], 'controlled': [510], 'either': [512, 2807], 'positive': [513], 'or': [514, 1486, 1639, 2686, 2903, 3188, 3194], 'belonging': [517, 590], 'separate': [519], 'families': [520, 598], 'factors': [523, 1408, 1762, 1986, 3824], 'containing': [524, 3585, 4326], '(bHLH)1': [530], 'motif.': [531], 'Proteins': [532], 'promote': [534], 'differentiation': [536, 754, 848, 1061, 1096, 1278], 'include': [537, 586, 849], 'number': [539, 1758, 3253], 'evolutionarily': [541], 'conserved': [542], 'activators,': [544], 'generally': [545], 'referred': [546, 1494, 2065], 'proneural': [550, 749, 1100], '(reviewed': [552, 1995], 'Refs.': [554], '1Kageyama': [555], 'R.': [556, 936, 998, 1002, 1040, 1044, 1077, 1117, 1141, 1163, 1199, 1203, 1226, 1334, 1420, 1559, 1563, 1600, 1664, 1680, 1727, 1797, 2244, 2248, 2285, 2349, 2389, 2492, 2496, 2527, 2546, 2706, 2758, 2786, 2874, 2935, 2963, 3075, 3137, 3156, 3261, 3265, 3302, 3335, 3396, 3460, 3537, 3879], 'Nakanishi': [557, 1003, 1045, 1074, 1114, 1136, 1158, 1204, 1221, 1564, 1661, 2249, 2497, 3266], 'S.': [558, 902, 974, 1004, 1046, 1075, 1115, 1137, 1159, 1205, 1222, 1236, 1352, 1438, 1499, 1508, 1565, 1582, 1606, 1662, 1686, 1711, 1731, 1774, 1784, 1805, 2250, 2267, 2291, 2326, 2336, 2357, 2498, 2511, 2531, 2554, 2650, 2714, 2766, 2790, 2810, 2819, 2835, 2882, 2912, 2921, 2943, 2967, 2983, 3028, 3079, 3141, 3164, 3267, 3284, 3308, 3339, 3363, 3380, 3400, 3468, 3514, 3523, 3541, 3670, 3680, 3718, 3746, 3754, 3766, 3883, 3933, 3961, 3969, 3981, 4021, 4110, 4245, 4267, 4277], 'Curr.': [559, 574], 'Opin.': [560, 575], 'Genet.': [561, 1510, 2821, 2923, 3525], 'Dev.': [562, 1006, 1048, 1121, 1143, 1207, 1373, 1459, 1526, 1567, 1584, 1607, 1688, 1855, 2110, 2147, 2252, 2269, 2292, 2409, 2500, 3269, 3286, 3309], '1997;': [563, 717, 1374, 1460, 2395, 2839, 2987, 3768, 3983, 4249], '7:': [564], '659-665Crossref': [565], 'PubMed': [566, 580, 614, 642, 671, 695, 720, 741, 789, 818, 839, 907, 922, 946, 979, 1083, 1125, 1147, 1169, 1232, 1260, 1344, 1361, 1377, 1430, 1447, 1463, 1514, 1530, 1588, 1613, 1670, 1692, 1719, 1738, 1789, 1817, 1841, 1859, 2014, 2114, 2133, 2151, 2171, 2200, 2273, 2298, 2341, 2369, 2398, 2414, 2519, 2538, 2566, 2668, 2726, 2778, 2796, 2825, 2847, 2894, 2927, 2955, 2973, 2995, 3043, 3085, 3148, 3176, 3290, 3315, 3346, 3372, 3388, 3407, 3480, 3529, 3547, 3696, 3733, 3771, 3794, 3889, 3948, 3986, 4036, 4125, 4257, 4293], 'Scopus': [567, 581, 615, 643, 672, 696, 721, 742, 790, 819, 840, 947, 1010, 1052, 1084, 1126, 1148, 1211, 1261, 1345, 1362, 1378, 1431, 1448, 1464, 1515, 1531, 1571, 1589, 1614, 1671, 1693, 1720, 1739, 1790, 1818, 1842, 1860, 2015, 2115, 2134, 2152, 2172, 2201, 2256, 2274, 2299, 2342, 2370, 2399, 2415, 2504, 2520, 2539, 2567, 2669, 2727, 2779, 2797, 2826, 2848, 2895, 2928, 2956, 2974, 2996, 3044, 3086, 3149, 3177, 3273, 3291, 3316, 3347, 3373, 3389, 3408, 3481, 3530, 3548, 3734, 3772, 3890, 3949, 3987, 4037, 4126, 4258], '(328)': [568], 'Google': [569, 583, 617, 645, 674, 698, 723, 744, 792, 821, 842, 908, 923, 949, 965, 980, 1012, 1054, 1086, 1128, 1150, 1170, 1213, 1233, 1263, 1347, 1364, 1380, 1433, 1450, 1466, 1517, 1533, 1573, 1591, 1616, 1628, 1673, 1695, 1722, 1741, 1792, 1820, 1844, 1862, 2017, 2117, 2136, 2154, 2174, 2203, 2258, 2276, 2301, 2313, 2344, 2372, 2384, 2401, 2417, 2506, 2522, 2541, 2569, 2671, 2729, 2781, 2799, 2828, 2850, 2897, 2930, 2958, 2976, 2998, 3046, 3088, 3151, 3179, 3275, 3293, 3318, 3330, 3349, 3375, 3391, 3410, 3483, 3532, 3550, 3697, 3736, 3774, 3795, 3892, 3951, 3989, 4039, 4128, 4260, 4294], 'Scholar': [570], '2Anderson': [572], 'D.J.': [573, 604, 632, 685, 779], 'Neurobiol.': [576], '1999;': [577, 1144, 1166, 1229, 1625, 1833, 1856, 2011, 2111, 2310, 2381, 3327], '9:': [578, 1123, 2012], '517-524Crossref': [579], '(121)': [582], 'Scholar).': [584, 745, 843, 981, 1013, 1055, 1087, 1171, 1264, 1381, 1467, 1696, 1742, 2018, 2204, 2418, 2570, 2730, 2800, 2999, 3047, 3089, 3411, 3698, 3796, 3893, 4129], 'These': [585, 859, 1468, 3412, 3608, 4419], 'related': [588, 2076], 'molecules': [589, 860], 'Neurogenin,': [593], 'Ash,': [594], 'Ath,': [595], 'NeuroD': [597], '(3Ma': [599], 'Q.': [600, 620, 711, 767], 'Kintner': [601], 'C.': [602, 648, 659, 795, 806, 896, 958, 972, 1249, 2864, 3739, 3954], 'Anderson': [603, 631, 684, 778], 'Cell.': [605, 688, 939, 1255, 1337, 1356, 1423, 1442, 1622, 2307, 2379, 3324, 3367, 3789], '1996;': [606, 962, 1358, 1444, 1527, 1716, 2163, 2516, 2793, 2970, 3082, 3369, 3385, 3544, 3886], '87:': [607], '43-52Abstract': [608], 'Full': [609, 611, 637, 639, 666, 668, 692, 784, 786, 813, 815, 943, 1341, 1427, 1812, 1814, 1836, 1838, 2166, 2168, 2364, 2366, 2561, 2563, 2663, 2665, 2721, 2723, 2773, 2775, 2842, 2844, 2889, 2891, 2950, 2952, 2990, 2992, 3171, 3173, 3475, 3477, 4252, 4254], 'Text': [610, 612, 638, 640, 667, 669, 693, 785, 787, 814, 816, 944, 1342, 1428, 1813, 1815, 1837, 1839, 2167, 2169, 2365, 2367, 2562, 2564, 2664, 2666, 2722, 2724, 2774, 2776, 2843, 2845, 2890, 2892, 2951, 2953, 2991, 2993, 3172, 3174, 3476, 3478, 4253, 4255], 'PDF': [613, 641, 670, 694, 788, 817, 945, 1343, 1429, 1816, 1840, 2170, 2368, 2565, 2667, 2725, 2777, 2846, 2893, 2954, 2994, 3175, 3479, 4256], '(715)': [616], 'Scholar,': [618, 646, 675, 699, 724, 793, 822, 909, 924, 950, 966, 1129, 1151, 1214, 1234, 1348, 1365, 1434, 1451, 1518, 1574, 1592, 1617, 1674, 1723, 1793, 1821, 1845, 2118, 2137, 2155, 2175, 2259, 2277, 2302, 2314, 2345, 2373, 2385, 2402, 2507, 2523, 2542, 2782, 2829, 2931, 2959, 2977, 3152, 3276, 3294, 3319, 3331, 3376, 3392, 3533, 3737, 3775, 3952, 4261], '4Ma': [619], 'Chen': [621, 768, 3780], 'Z.': [622, 769, 926, 1324, 1369, 1410, 1455, 1776, 2328], 'del': [623, 770, 2141], 'Barco': [624, 771], 'Barrantes': [625, 772], 'I.': [626, 773, 1682], 'de': [627, 774, 2189], 'la': [628, 775], 'Pompa': [629, 776], 'J.L.': [630, 777, 2003, 3682, 3744, 3959, 4279], 'Neuron.': [633, 662, 780, 809], '1998;': [634, 663, 781, 810, 1257, 1610, 1735, 1786, 2197, 2295, 2338, 2535, 3145, 3312, 3343, 3404, 3791], '20:': [635, 664, 782, 811, 2396], '469-482Abstract': [636, 783], '(603)': [644, 791], '5Fode': [647, 794], 'Gradwohl': [649, 796, 1156, 1219], 'G.': [650, 797, 1157, 1220, 1367, 1453, 1576, 1803, 2261, 2355, 2552, 2712, 2764, 2880, 2941, 3162, 3278, 3466], 'Morin': [651, 798], 'X.': [652, 799], 'Dierich': [653, 800], 'A.': [654, 683, 801, 898, 970, 1253, 1602, 1684, 1785, 2287, 2337, 2404, 2406, 2831, 2833, 2979, 2981, 3304, 3666, 3767, 3982, 4241, 4243, 4263], 'Le': [655, 802, 1237], 'Meur': [656, 803], 'M.': [657, 804, 954, 1067, 1109, 1133, 1155, 1218, 1354, 1440, 1654, 2139, 2157, 2179, 2191, 2387, 2393, 3365], 'Goridis': [658, 805], 'Guillemot': [660, 807, 1118, 1160, 1223], 'F.': [661, 677, 808, 915, 1119, 1161, 1224, 1245, 2143, 2408], '483-494Abstract': [665, 812], '(383)': [673, 820], '6Guillemot': [676], 'Lo': [678, 1599, 1679, 1726, 1796, 2284, 2348, 2526, 2545, 2705, 2757, 2785, 2873, 2934, 2962, 3074, 3136, 3155, 3301, 3334, 3395, 3459, 3536, 3878], 'L.C.': [679], 'Johnson': [680], 'J.E.': [681, 726, 824], 'Auerbach': [682], 'Joyner': [686], 'A.L.': [687, 1350, 1436, 3361], '1993;': [689, 2130, 2148], '75:': [690], '463-476Abstract': [691], '(914)': [697], '7Ben-Arie': [700], 'N.': [701, 734, 832, 1139, 2652], 'Bellen': [702], 'H.J.': [703, 1827], 'Armstrong': [704], 'D.L.': [705, 732, 830], 'McCall': [706], 'A.E.': [707], 'Gordadze': [708], 'P.R.': [709], 'Guo': [710, 3667, 4264], 'Matzuk': [712], 'M.M.': [713], 'Zoghbi': [714], 'H.Y.': [715], 'Nature.': [716, 2196], '390:': [718], '169-172Crossref': [719], '(531)': [722], '8Lee': [725, 823], 'Hollenberg': [727, 825], 'S.M.': [728, 826, 932, 1330, 1416], 'Snider': [729, 827], 'L.': [730, 828, 956, 3750, 3965], 'Turner': [731, 829], 'Lipnick': [733, 831], 'Weintraub': [735, 833], 'H.': [736, 834, 913, 1770, 2120, 2185, 2195, 2322, 2644, 2646], 'Science.': [737, 835], '1995;': [738, 836, 1122, 1585, 2270, 2411, 3040, 3287, 3730, 3945, 4033, 4122], '268:': [739, 837], '836-844Crossref': [740, 838], '(927)': [743, 841], 'Ectopic': [746], 'expression': [747, 1027, 1057, 1636, 1980, 3489, 3815], 'results': [751, 2020, 3609], 'supernumerary': [756], 'neurons,': [757], 'whereas': [758, 4166], 'disruption': [759, 1090], 'their': [761, 1899], 'functions': [762, 880, 1290, 1901, 2100], 'causes': [763, 1093], 'loss': [765, 1652], '(4Ma': [766], 'Factors': [844], 'antagonize': [846], 'bHLH': [850], 'mediate': [853], 'rather': [856], 'than': [857], 'transactivation.': [858], 'homologous': [862], 'Drosophila': [865, 1174, 1310, 1393], '(Hes)': [869], 'proteins,': [870, 1176, 3701, 3922], 'control': [872], 'insect': [873], 'development': [875], 'negatively': [877, 2219], 'neurogenic': [883], 'genes': [884, 1488], 'activation': [888], 'cell': [891, 3256], 'surface': [892], 'receptor,': [893], 'Notch': [894, 1190], '(9Delidakis': [895], 'Preiss': [897, 969], 'Hartley': [899], 'D.A.': [900], 'Artavanis-Tsakonas': [901], 'Genetics.': [903, 918], '1991;': [904], '129:': [905], '803-823Crossref': [906], '10Knust': [910], 'E.': [911, 1135, 1241, 3032, 3722, 3783, 3937, 4025, 4114], 'Schrons': [912], 'Grawe': [914], 'Campos-Ortega': [916], 'J.A.': [917], '1992;': [919, 1007, 1049, 1208, 1511, 1568, 2253, 2501, 2822, 2924, 3270, 3526], '132:': [920], '505-518Crossref': [921], '11Paroush': [925], 'Finley': [927, 1325, 1411], 'R.L.': [928, 1326, 1412], 'Kidd': [929, 1327, 1413], 'T.': [930, 1153, 1216, 1328, 1414, 1619, 1853, 2108, 2145, 2304, 2642, 2648, 2656, 2678, 3321, 3777], 'Wainwright': [931, 1329, 1415], 'Ingham': [933, 1331, 1417], 'P.W.': [934, 1332, 1418], 'Brent': [935, 1333, 1419], 'Ish-Horowicz': [937, 1335, 1370, 1421, 1456], 'D.': [938, 1336, 1371, 1422, 1457, 1709, 1725, 1764, 1772, 1799, 2316, 2324, 2351, 2509, 2525, 2548, 2708, 2760, 2788, 2865, 2876, 2937, 2965, 3077, 3135, 3158, 3333, 3378, 3394, 3462, 3539, 3881], '1994;': [940, 976, 1080, 1338, 1424, 1667], '79:': [941, 1339, 1425], '805-815Abstract': [942, 1340, 1426], '(492)': [948, 1346, 1432], '12Heitzler': [951], 'P.': [952, 960, 2187], 'Bourouis': [953], 'Ruel': [955], 'Carteret': [957], 'Simpson': [959], 'Development.': [961, 975], '122:': [963], '161-171PubMed': [964], '13Jennings': [967], 'B.': [968, 1847, 2102, 3668, 4265], 'Delidakis': [971], 'Bray': [973], '120:': [977], '3537-3548Crossref': [978], 'best': [983], 'characterized': [984, 1649], 'member': [985], 'Hes': [989, 1175, 1314, 1394], 'family': [990, 1878, 2226, 3704, 3925], '(14Sasai': [995, 1037, 1196, 1556, 2241, 2489, 3258], 'Y.': [996, 1000, 1038, 1042, 1071, 1197, 1201, 1557, 1561, 1578, 1596, 1658, 1678, 1729, 1768, 1778, 1829, 2242, 2246, 2263, 2281, 2320, 2330, 2490, 2494, 2529, 3139, 3259, 3263, 3280, 3298, 3337, 3398, 3779, 3787], 'Kageyama': [997, 1039, 1076, 1116, 1140, 1162, 1198, 1225, 1558, 1663, 2243, 2388, 2491, 3260], 'Tagawa': [999, 1041, 1200, 1560, 2245, 2493, 3262], 'Shigemoto': [1001, 1043, 1202, 1562, 2247, 2495, 3264], 'Genes': [1005, 1047, 1120, 1142, 1206, 1372, 1458, 1566, 1854, 2109, 2251, 2499, 3268], '5:': [1008, 1050, 1209, 1569, 2254, 2502, 3271], '2620-2634Crossref': [1009, 1051, 1210, 1570, 2255, 2503, 3272], '(574)': [1011, 1053, 1212, 1572, 2257, 2505, 3274], 'Hes1is': [1018], 'highly': [1019], 'expressed': [1020, 3225, 3598], 'during': [1021, 1030, 1193], 'progenitor-to-neuron': [1023], 'transition,': [1024], 'its': [1026, 1288, 4436], 'then': [1028, 2615, 3648, 3842, 4094], 'decreases': [1029], 'maturation': [1033], 'postmitotic': [1035], 'Persistent': [1056], 'Hes1inhibits': [1059], 'developing': [1064], 'telencephalon': [1065], '(15Ishibashi': [1066, 1653], 'Moriyoshi': [1068, 1655], 'K.': [1069, 1073, 1113, 1131, 1656, 1660, 1801, 2353, 2550, 2654, 2710, 2762, 2878, 2939, 3160, 3464], 'Sasai': [1070, 1657], 'Shiota': [1072, 1112, 1659], 'EMBO': [1078, 1164, 1227, 1665], 'J.': [1079, 1165, 1228, 1580, 1594, 1598, 1604, 1666, 1676, 1733, 1806, 1830, 2128, 2160, 2177, 2181, 2183, 2265, 2279, 2283, 2289, 2358, 2378, 2533, 2555, 2657, 2715, 2767, 2784, 2792, 2836, 2883, 2944, 2961, 2969, 2984, 3034, 3036, 3073, 3081, 3143, 3165, 3282, 3296, 3300, 3306, 3341, 3402, 3469, 3535, 3543, 3674, 3690, 3724, 3726, 3877, 3885, 3939, 3941, 4027, 4029, 4116, 4118, 4246, 4271, 4287], '13:': [1081, 1145, 1668, 1857, 2112], '1799-1805Crossref': [1082, 1669], '(336)': [1085, 1672], 'Conversely,': [1088], 'targeted': [1089], 'premature': [1094], 'up-regulation': [1098], 'genes,': [1101], 'addition': [1103], 'other': [1105, 3618, 3919], 'defects': [1107], '(16Ishibashi': [1108], 'Ang': [1110], 'S.L.': [1111], '3136-3148Crossref': [1124], '(416)': [1127], '17Tomita': [1130], 'Hattori': [1132], 'Nakamura': [1134], 'Minato': [1138], '1203-1210Crossref': [1146], '(181)': [1149], '18Ohtsuka': [1152, 1215], 'Ishibashi': [1154, 1217], '18:': [1167, 1230, 1258, 3792], '2196-2207Crossref': [1168, 1231], 'Similar': [1172], 'effector': [1187], 'signaling': [1191], 'pathway': [1192], 'neurogenesis': [1195], '19Jarriault': [1235], 'Bail': [1238], 'O.': [1239, 1243, 2193], 'Hirsinger': [1240], 'Pourquie': [1242], 'Logeat': [1244], 'Strong': [1246], 'C.F.': [1247], 'Brou': [1248], 'Seidah': [1250], 'N.G.': [1251], 'Israel': [1252], 'Mol.': [1254, 1355, 1441, 1623, 2308, 3325, 3366, 3788], 'Biol.': [1256, 1357, 1443, 1624, 1807, 1831, 2161, 2309, 2359, 2556, 2658, 2716, 2768, 2837, 2884, 2945, 2985, 3166, 3326, 3368, 3470, 3790, 4247], '7423-7431Crossref': [1259], '(279)': [1262], 'findings': [1267, 1469, 2208, 2422, 3413, 4297, 4420], 'demonstrate': [1268, 1909, 4421], 'regulator': [1275, 2092], 'mammals': [1280], 'underscore': [1282], 'importance': [1284], 'understanding': [1286], 'how': [1287, 1898], 'cellular': [1289], 'regulated.': [1292, 1903], 'Although': [1293], 'little': [1294], 'presently': [1296], 'known': [1297, 3662], 'about': [1298], 'underlie': [1303], 'studies': [1308, 1966, 2803], 'show': [1311, 2022, 3610, 4298], 'invertebrate': [1313], 'interact': [1316, 1892, 2029, 3441, 3615], 'general': [1319], 'corepressor,': [1321], '(11Paroush': [1323, 1409], '20Fisher': [1349, 1435], 'Ohsako': [1351, 1437, 3362], 'Caudy': [1353, 1439, 3364], '16:': [1359, 1445, 3370], '2670-2677Crossref': [1360, 1446, 3371], '(306)': [1363, 1449, 3374], '21Jimenez': [1366, 1452], 'Paroush': [1368, 1454, 1775, 2327], '11:': [1375, 1461], '3072-3082Crossref': [1376, 1462], '(209)': [1379, 1465], 'Mutations': [1382], 'Groucho·Hes': [1386], 'interfere': [1388], 'repress': [1397], 'transcription,': [1398], 'suggesting': [1399], 'first': [1470, 2079, 3433], 'raised': [1471], 'possibility': [1473, 4046], 'homologs': [1476], 'DrosophilaGroucho,': [1478], 'designated': [1479], '(TLE)': [1485], '(Grg)': [1489], 'through': [1491], '4': [1492], '(hereafter': [1493, 2064], 'TLE1–4)': [1497], '(22Stifani': [1498, 2809, 2911, 3513], 'Blaumueller': [1500, 2811, 2913, 3515], 'C.M.': [1501, 2812, 2914, 3516], 'Redhead': [1502, 2813, 2915, 3517], 'N.J.': [1503, 2814, 2916, 3518], 'Hill': [1504, 2815, 2917, 3519], 'R.E.': [1505, 1766, 2318, 2816, 2918, 3520], 'Artavanis-': [1506, 2817, 2919, 3521], 'Tsakonas': [1507, 2818, 2920, 3522], 'Nat.': [1509, 2820, 2922, 3524], '2:': [1512, 2823, 2925, 3527], '119-127Crossref': [1513, 2824, 2926, 3528], '(261)': [1516, 2827, 2929, 3531], '23Koop': [1519], 'K.E.': [1520], 'MacDonald': [1521], 'L.M.': [1522], 'Lobe': [1523, 1620, 2158, 2305, 3322], 'C.G.': [1524, 1621, 2159, 2306, 3323], 'Mech.': [1525, 1583, 1687, 2146, 2268, 3285], '59:': [1528], '73-87Crossref': [1529], '(72)': [1532, 2173], 'Scholar),': [1534, 1629, 1863, 2851, 2898, 3180, 3484, 3990, 4295], 'may': [1535, 3417], 'be': [1536, 1883, 4231], 'involved': [1537, 1974], 'Consistent': [1543], 'notion,': [1546], 'TLEgenes': [1549], 'coexpressed': [1551, 3247], 'system': [1555], '24Dehni': [1575, 2260, 3277], 'Liu': [1577, 1595, 1677, 1728, 2262, 2280, 2528, 3138, 3279, 3297, 3336, 3397], 'Husain': [1579, 1597, 2264, 2282, 3281, 3299], 'Stifani': [1581, 1605, 1685, 1710, 1730, 1773, 1804, 2266, 2290, 2325, 2356, 2510, 2530, 2553, 2713, 2765, 2789, 2834, 2881, 2942, 2966, 2982, 3078, 3140, 3163, 3283, 3307, 3338, 3379, 3399, 3467, 3540, 3679, 3882, 4244, 4276], '53:': [1586, 2271, 3288], '369-381Crossref': [1587, 2272, 3289], '(61)': [1590, 2153, 2275, 3292], '25Yao': [1593, 2278, 3295], 'Palaparti': [1601, 2286, 3303], 'Henderson': [1603, 2288, 3305], 'Growth': [1608, 2293, 3310], 'Differ.': [1609, 2294, 3311], '40:': [1611, 2296, 3313], '133-146Crossref': [1612, 2297, 3314], '(59)': [1615, 2300, 3317], '26Allen': [1618, 2303, 3320], '45:': [1626, 2311, 3328], '687-708PubMed': [1627, 2312, 3329], 'perturbations': [1631], 'force': [1633], 'persistent': [1635], 'TLE1': [1640, 1703, 3355], 'forebrain': [1644], 'result': [1645], 'similar': [1647, 3915, 4305], 'phenotypes': [1648], '27Yao': [1675], 'Tretjakoff': [1681], 'Peterson': [1683, 2180], '2000;': [1689, 1809, 2361, 2558, 2660, 2718, 2770, 2886, 2947, 3168, 3472, 3693, 4290], '93:': [1690], '105-115Crossref': [1691], '(46)': [1694, 2798, 2975, 3087, 3549, 3891], 'addition,': [1698], 'physically': [1700, 3352], 'TLE2': [1705, 3357], 'vitro': [1707, 3359], '(28Grbavec': [1708], 'Biochem.': [1712, 1734, 2129, 2380, 2512, 2534, 2791, 2968, 3080, 3144, 3342, 3381, 3403, 3542, 3884], 'Biophys.': [1713, 2513, 3382], 'Res.': [1714, 2514, 3383], 'Commun.': [1715, 2515, 3384], '223:': [1717, 2517, 3386], '701-705Crossref': [1718, 2518, 3387], '(131)': [1721, 2521, 3390], '29Grbavec': [1724, 2524, 3332, 3393], 'Eur.': [1732, 2127, 2532, 3142, 3340, 3401], '258:': [1736, 2536, 3146, 3344, 3405], '339-349Crossref': [1737, 2537, 3147, 3345, 3406], '(79)': [1740, 2540, 3150, 3348, 3409], 'Taken': [1743, 2419], 'together': [1744], 'demonstration': [1747], 'TLE': [1749, 1877, 1889, 2097, 2239, 3249, 3438, 3555, 3637, 3659, 4224, 4313], 'provide': [1751, 3213], 'function': [1755, 2057], 'different': [1760, 3846], 'DNA-binding': [1761], '(30Levanon': [1763], 'Goldstein': [1765, 2317], 'Bernstein': [1767, 2319], 'Tang': [1769, 2321], 'Goldenberg': [1771, 2323], 'Groner': [1777, 2329], 'Proc.': [1779, 2331, 3761, 3976], 'Natl.': [1780, 2332, 3762, 3977], 'Acad.': [1781, 2333, 3763, 3978], 'Sci.': [1782, 2334, 3692, 3764, 3979, 4289], 'U.': [1783, 2335, 3765, 3980], '95:': [1787, 2339], '11590-11595Crossref': [1788, 2340], '(407)': [1791, 2343], '31McLarren': [1794, 2346, 2543, 2932, 3153], 'K.W.': [1795, 2347, 2544, 2704, 2756, 2872, 2933, 3154, 3458], 'Grbavec': [1798, 2350, 2547, 2707, 2759, 2787, 2875, 2936, 2964, 3076, 3157, 3461, 3538, 3880], 'Thirunavukkarasu': [1800, 2352, 2549, 2709, 2761, 2877, 2938, 3159, 3463], 'Karsenty': [1802, 2354, 2551, 2711, 2763, 2879, 2940, 3161, 3465], 'Chem.': [1808, 1832, 2162, 2360, 2557, 2659, 2717, 2769, 2838, 2885, 2946, 2986, 3167, 3471, 4248], '275:': [1810, 2362, 2559, 2661, 2719, 2771, 2887, 2948, 3169, 3473], '530-538Abstract': [1811, 2363, 2560, 2720, 2772, 2888, 2949, 3170, 3474], '(151)': [1819, 2371, 2568, 2728, 2780, 2896, 2957, 3178, 3482], '32Choi': [1822], 'C.Y.': [1823], 'Kim': [1824, 1828, 1850, 2105, 3784], 'Y.H.': [1825], 'Kwon': [1826], '274:': [1834], '33194-33197Abstract': [1835], '(139)': [1843], '33Ren': [1846], 'Chee': [1848, 2103], 'K.J.': [1849, 2104], 'T.H.': [1851, 2106], 'Maniatis': [1852, 2107], '125-137Crossref': [1858, 2113], '(214)': [1861, 2116], 'regulated': [1873, 2060, 2220], 'members.': [1879], 'remains': [1881], 'determined,': [1884], 'however,': [1885], 'whether': [1886, 3435, 3634, 3650], 'functionally': [1891, 1973], 'vivo': [1894], 'and,': [1895], 'if': [1896], 'so,': [1897], 'Here': [1904], 'we': [1905, 3432], 'describe': [1906], 'experiments': [1907, 2470, 2744], 'TLEs': [1914, 1925, 2031, 2044, 2054, 2215, 3416, 3456, 3566, 3612], 'where': [1924, 3658], 'found.': [1928], 'domain,': [1948], 'correlation': [1951, 4423], 'between': [1952, 4424], 'observation': [1960], 'agreement': [1963, 4208], 'previous': [1965], 'showing': [1967], 'concentrating': [1982], 'localizing': [1984], 'and/or': [1987, 3825], 'facilitating': [1988, 3826], 'formation': [1990], 'appropriate': [1992, 2578, 2594, 3830], 'chromatin': [1993, 3831, 4077, 4150, 4235], 'structures': [1994], 'Ref.34Stein': [1997], 'G.S.': [1998, 3038, 3689, 3728, 3758, 3943, 3973, 4031, 4120, 4286], 'van': [1999, 2188, 3024, 3685, 3714, 3740, 3929, 3955, 4017, 4106, 4282], 'Wijnen': [2000, 3025, 3686, 3715, 3741, 3930, 3956, 4018, 4107, 4283], 'A.J.': [2001, 3026, 3687, 3716, 3742, 3931, 3957, 4019, 4108, 4284], 'Stein': [2002, 3035, 3037, 3681, 3688, 3725, 3727, 3743, 3757, 3940, 3942, 3958, 3972, 4028, 4030, 4117, 4119, 4278, 4285], 'Lian': [2004, 3033, 3683, 3723, 3755, 3938, 3970, 4026, 4115, 4280], 'J.B.': [2005, 3684, 3752, 3756, 3967, 3971, 4281], 'Crit.': [2006], 'Rev.': [2007], 'Eukaryot.': [2008], 'Gene': [2009], 'Expr.': [2010], '183-190Crossref': [2013], '(21)': [2016], 'Our': [2019], 'repression,': [2041], 'corepressors': [2048], 'involvement': [2052], 'AES1/Grg5': [2063], 'Grg5)': [2068], 'protein.': [2069], 'Grg5': [2070], 'naturally': [2073], 'occurring': [2074], 'factor': [2075], '200': [2080], 'amino': [2081, 2623, 3583, 4324], 'acids': [2082, 2624, 3584, 4325], 'Groucho/TLEs': [2084], 'has': [2086, 4301], 'been': [2087, 2486, 4227], 'regarded': [2088], 'dominant-negative': [2091], 'least': [2095], 'certain': [2096], '(33Ren': [2101], '35Miyasaka': [2119], 'Choudhury': [2121], 'B.K.': [2122], 'Hou': [2123], 'E.W.': [2124], 'Li': [2125], 'S.S.L.': [2126], '216:': [2131], '343-352Crossref': [2132], '(64)': [2135], '36Mallo': [2138], 'Franco': [2140], 'Amo': [2142], 'Gridley': [2144], '42:': [2149], '67-76Crossref': [2150], '37Pinto': [2156], '271:': [2164], '33026-33031Abstract': [2165], '38Roose': [2176], 'Molenaar': [2178], 'Hurenkamp': [2182], 'Brantjes': [2184], 'Moerer': [2186], 'Wetering': [2190], 'Destree': [2192], 'Clevers': [2194], '395:': [2198], '608-612Crossref': [2199], '(568)': [2202], 'our': [2207], 'members': [2222, 3926], 'factors,': [2229], 'coexpressed,': [2232], 'interact,': [2234], '30Levanon': [2315], '39Westendorf': [2374], 'J.J.': [2375], 'Hiebert': [2376, 3027, 3669, 3717, 3759, 3932, 3974, 4020, 4109, 4266], 'S.W.': [2377, 3760, 3975], '32–33:': [2382], '51-58Crossref': [2383], '40Matsue': [2386], 'Denhardt': [2390], 'D.T.': [2391], 'Noda': [2392], 'Bone.': [2394], '329-334Crossref': [2397], '(31)': [2400], '41Simeone': [2403], 'Daga': [2405], 'Calabi': [2407], 'Dyn.': [2410], '203:': [2412], '61-70Crossref': [2413], '(73)': [2416], 'together,': [2420], 'among': [2426], 'TLE,': [2428], 'following': [2443], 'summary': [2446], 'names': [2449], 'origins': [2451], 'constructs': [2454], 'used': [2455, 2467, 3116, 4389], 'studies.': [2458], 'Additional': [2459], 'information': [2460], 'on': [2461, 3503], 'cloning': [2462], 'strategies': [2463], 'oligonucleotide': [2465], 'primers': [2466], 'PCR': [2469, 2579, 2595], 'available': [2472], 'upon': [2473], 'request.': [2474], 'Constructs': [2475], 'pEBG-Hes1,': [2476], 'pCMV2-FLAG-Hes1,pCMV2-FLAG-Hes1-(1–275),': [2477], 'pcDNA3-TLE1,pCMV5-RUNX2,': [2478], 'pGEX3-TLE3(': [2479], 'WDR': [2480], '),pRc/CMV-Hes1,': [2481], 'pBluescript-RUNX2,': [2482], 'p6N-βAct-luc': [2484, 3184], 'have': [2485, 4226], 'described': [2487, 2701, 2753, 2909, 3017, 3070, 3133, 3874, 4221], 'previously': [2488, 2702, 2754, 2910, 3071, 3875, 4229], '28Grbavec': [2508, 3377], 'Plasmid': [2571, 2604], 'pEBG-Hes-(1–275)': [2572], 'obtained': [2574, 2606, 3872], 'subcloning': [2576, 2592, 2616], 'filled-in': [2583, 2599], 'BamHI': [2584, 2600], 'pEBG.': [2587], 'pCMV2-FLAG-Hes-(1–227)': [2588], 'generated': [2590], 'pCMV2-FLAG.': [2603], 'pcDNA3-GAL4bd-Hes1-(193–281)was': [2605], 'digesting': [2608], 'pRc/CMV-Hes1': [2610], 'SmaI': [2613], 'fragment': [2618], 'encoding': [2619], 'last': [2621, 3581, 4322], '88': [2622], '(plus': [2627], '∼1.2': [2628], 'kb': [2629], '3′-untranslated': [2631], 'region)': [2632], 'EcoRV': [2635], 'pcDNA3-GAL4bd.': [2638], 'Construct': [2639], 'pCMV-Grg5': [2640], '(42Tetsuka': [2641], 'Uranishi': [2643], 'Imai': [2645], 'Ono': [2647], 'Sontar': [2649], 'Takahashi': [2651], 'Asamitsu': [2653], 'Okamoto': [2655, 2679], '4383-4390Abstract': [2662], '(78)': [2670], 'Scholar)': [2672, 3350, 3551, 4040], 'kindly': [2674], 'provided': [2675], 'Dr.': [2677, 2863], '(Nagoya': [2680], 'University).': [2681], 'Human': [2682, 3090], '293': [2683, 3091], 'embryonic': [2684], 'kidney': [2685], 'rat': [2687], 'ROS17/2.8': [2688, 3000, 3447, 3833], 'osteoblastic': [2689, 3448], 'were': [2691, 2749, 2804, 3002, 3054, 3093, 3130, 3224, 3231, 3485, 3597, 3835, 3862, 3871, 4056], 'grown': [2692], 'transfected': [2694, 3094, 3103, 3486, 3836], 'using': [2695, 2733, 3095, 3106, 3181], 'SuperFect': [2697, 3097], 'reagent': [2698], '(Qiagen)': [2699], '(31McLarren': [2703, 2755, 2871, 3457], 'Coprecipitation': [2731], 'assays': [2732, 3129, 3219], 'plasmids': [2734], 'pEBG-Hes1': [2735], 'pEBG-Hes1-(1–275)': [2737], '(or': [2738], 'pEBG': [2739], 'control)': [2741], 'immunoprecipitation': [2743], 'anti-FLAG-epitope': [2746], 'antibodies': [2747, 2907, 3512], '(Sigma)': [2748], 'performed': [2750, 2805, 3131], 'exactly': [2751, 3015], '43Husain': [2783, 2960, 3534], '317:': [2794, 2971, 3083, 3545, 3887], '523-531Crossref': [2795, 2972, 3084, 3546, 3888], 'Western': [2801, 3506, 4139], 'blotting': [2802, 3507, 4140], 'panTLE': [2808, 3510], '44Palaparti': [2830, 2978], 'Baratz': [2832, 2980, 4242], '272:': [2840, 2988, 4250], '26604-26610Abstract': [2841, 2989, 4251], '(130)': [2849, 2997, 4259], 'anti-GST': [2852], '(Santa': [2853, 2900], 'Cruz': [2854, 2901], 'Biotechnology),': [2855, 2902], 'anti-FLAG,': [2856], 'anti-histone': [2857], 'H3': [2858, 4153], '(a': [2859], 'kind': [2860], 'gift': [2861], 'Allis,': [2866], 'University': [2867], 'Rochester),': [2869], 'anti-RUNX2': [2870], 'anti-GAL4bd': [2899], 'anti-lamin': [2904], 'B1': [2905, 4172], '(Chemicon)': [2906], 'subjected': [3003, 3843], 'sequential': [3005], 'extraction': [3006], 'solubilization': [3008], 'steps': [3009], 'isolate': [3011], 'Merriman': [3019, 4012], 'et': [3020, 4013], 'al.': [3021, 4014], '(45Merriman': [3022, 3712, 3927, 4015, 4104], 'H.L.': [3023, 3713, 3928, 4016, 4105], 'Bidwell': [3029, 3719, 3934, 4022, 4111], 'J.P.': [3030, 3720, 3935, 4023, 4112], 'Fey': [3031, 3721, 3936, 4024, 4113], 'Biochemistry.': [3039, 3729, 3944, 4032, 4121], '34:': [3041, 3731, 3946, 4034, 4123], '13125-13132Crossref': [3042, 3732, 3947, 4035, 4124], '(218)': [3045, 3735, 3950, 4038, 4127], 'High': [3048], 'salt-resistant': [3049, 4218], '-soluble': [3051], 'fractions': [3053, 3870, 4200, 4395], 'prepared': [3055], 'subjecting': [3057], 'isolated': [3058, 3863], 'nuclei': [3059, 3861, 3899], 'incubation': [3061], 'presence': [3064, 3189], '0.5': [3066], 'm': [3067], 'NaCl': [3068], '(43Husain': [3072, 3876], 'reagent.': [3098], 'amount': [3100, 3113, 4187, 4359], 'adjusted': [3105], 'pcDNA3': [3107], 'plasmid': [3108, 3183, 3208], 'so': [3109], 'total': [3112], 'each': [3118, 3202, 3617], 'transfection': [3119, 3221], '(3.0': [3123], 'μg).': [3124], 'Twenty-four': [3125], 'hours': [3126], 'later,': [3127], '(29Grbavec': [3134], 'reporter': [3182], 'absence': [3187], 'pCMV2-FLAG-Hes1,': [3191], 'pCMV2-FLAG-Hes1-(1–227),pcDNA3-TLE1,': [3192], 'pCMV-Grg5,': [3193], 'pCMV5-RUNX2as': [3195], 'indicated': [3196], 'figure': [3199], 'legends.': [3200], 'case,': [3203], '0.25': [3204], 'μg': [3205], 'pCMV-β-galactosidase': [3207], 'cotransfected': [3211], 'means': [3215], 'normalizing': [3217], 'efficiency.': [3222], 'Results': [3223], 'mean': [3227], '±': [3228], 'S.D.': [3229], 'tested': [3232], 'statistical': [3234], 'significance': [3235], 'one-tailed': [3238], "Student's": [3239], 't': [3240], 'test': [3241, 4044], 'paired': [3243], 'differences.': [3244], 'types': [3257], '(20Fisher': [3360], 'form': [3418, 4374], 'complexes': [3421], 'vivo.': [3425], 'To': [3426, 3632, 4002], 'begin': [3427], 'examine': [3429], 'possibility,': [3431, 4005], 'asked': [3434, 3649], 'would': [3440], 'cultured': [3443], 'cells.': [3445], 'Rat': [3446], 'cells,': [3449], 'express': [3451], 'high': [3452, 3865, 3901, 4217], 'levels': [3453, 3601], 'endogenous': [3455, 3554], 'an': [3488, 4355], 'construct': [3490], 'fusion': [3493, 3572], 'GST': [3496, 3575], 'After': [3499], 'isolation': [3500, 4009], 'GST-Hes1': [3502, 3559, 3594], 'glutathione-Sepharose': [3504], 'beads,': [3505], 'analysis': [3508, 4141], 'monoclonal': [3511], 'revealed': [3552], 'coprecipitated': [3557], '(Fig.1': [3560, 3602], 'A,': [3561, 3591, 4070], 'lane': [3562, 3592, 4164, 4348, 4370], '2).': [3563, 3911], 'did': [3567], 'coprecipitate': [3569], 'Hes1-(1–275),': [3577, 4376], 'lacks': [3579], 'six': [3582, 4323], '(Fig.': [3589, 3905, 4161, 4181, 4345, 4367, 4396], '4).': [3593, 3607], 'GST-Hes1-(1–275)': [3596], 'equivalent': [3600], 'B,': [3603, 4163], 'lanes': [3604, 3908, 4203], '2': [3605, 3906, 4162, 4182, 4204, 4346, 4368, 4397], 'determine': [3633, 3852], 'might': [3639, 4049], 'colocalize': [3640], 'common': [3643], 'compartment,': [3645], 'it': [3646], 'could': [3652], 'associate': [3653, 3707, 4050, 4430], 'localize': [3664], '(46Javed': [3665], 'Choi': [3671, 4268], 'J.Y.': [3672, 4269], 'Green': [3673, 4270], 'Zhao': [3675, 4272], 'S.C.': [3676, 4273], 'Osborne': [3677, 4274], 'M.A.': [3678, 4275], 'Cell': [3691, 4288], '113:': [3694, 4291], '2221-2231Crossref': [3695, 4292], 'Other': [3699], 'Hes1-binding': [3700], 'like': [3702], 'members,': [3705], '47Zeng': [3738, 3953], 'Meyers': [3745, 3960], 'Sun': [3747, 3962], 'W.': [3748, 3963], 'Shopland': [3749, 3964], 'Lawrence': [3751, 3966], 'Penman': [3753, 3968], '94:': [3769, 3984], '6746-6751Crossref': [3770, 3985], '(224)': [3773, 3988], '48Kanno': [3776], 'Kanno': [3778], 'L.-F.': [3781], 'Ogawa': [3782], 'W.-Y.': [3785], 'Ito': [3786], '2444-2454Crossref': [3793], 'filamentous': [3798], 'thought': [3805], 'play': [3807], 'mediating': [3817], 'colocalization': [3819], 'establishment': [3828], 'structures.': [3832], 'FLAG': [3838, 4380], 'epitope-tagged': [3839], 'two': [3845], 'kinds': [3847], 'biochemical': [3849], 'fractionation': [3850, 4134], 'subnuclear': [3854, 4303], 'localization': [3855], 'one': [3859], 'procedure,': [3860], 'salt-soluble': [3866], '-insoluble': [3868], 'poorly': [3896], 'extracted': [3897, 4095], 'from': [3898], 'ionic': [3902], 'strength': [3903], 'conditions': [3904, 4388], 'A,cf.': [3907], 'behavior': [3913], 'suggests': [3992], 'tightly': [3996], 'associated': [3997, 4232], 'internal': [3999], 'compartments.': [4001], 'confirm': [4003], 'procedure': [4010, 4135], 'utilized': [4042], 'compartment.': [4053], 'Cytoplasmic': [4054], 'extracted,': [4057], 'remaining': [4060, 4091], 'insoluble': [4061], 'fraction': [4062, 4160, 4180, 4220, 4366], 'treated': [4064], 'DNase': [4066], 'I': [4067], 'RNase': [4069], 'followed': [4071], 'ammonium': [4073], 'sulfate': [4074], 'release': [4076], 'components': [4078], 'bound': [4085], 'pellet': [4092], 'disassembly': [4097], 'buffer': [4098], 'yield': [4100], 'effectiveness': [4131], 'confirmed': [4137], 'cytoplasmic,': [4143], 'nuclease-treated,': [4144], 'fractions.': [4148], 'component,': [4151], 'histone': [4152], 'present': [4155], 'only': [4156, 4174], 'nuclease-treated': [4159, 4196], '2),': [4165], 'protein,': [4170], 'lamin': [4171], 'recovered': [4175], 'C,lane': [4183], '3).': [4184, 4349], 'A': [4185, 4372], 'significant': [4186], 'immunoreactivity': [4190], 'found': [4192, 4362, 4414], '(Fig.2': [4201], 'D,': [4202], '3),': [4206], 'tight': [4211], 'above.': [4222], 'Because': [4223], '(44Palaparti': [4240], '46Javed': [4262], 'distribution': [4304], 'TLEs.': [4309], 'Elimination': [4310], 'removal': [4319], '(resulting': [4330], 'truncated': [4333], 'Hes1-(1–275))': [4335], 'almost': [4336], 'completely': [4337], 'abolished': [4338], 'E,': [4347, 4369], 'situation': [4351], 'correlated': [4353], 'increase': [4356], 'cytoplasmic': [4365, 4417], '1).': [4371, 4399], 'smaller': [4373], 'retaining': [4377], 'epitope,': [4381], 'observed': [4384], 'under': [4385], 'experimental': [4387], 'prepare': [4391], 'non-nuclear': [4392], 'E,lane': [4398], 'faster-migrating': [4401], 'species,': [4402], 'likely': [4403], 'representing': [4404], 'proteolytic': [4410], 'degradation,': [4411], 'predominantly': [4413], 'fraction.': [4418], 'inter': [4439]}, 'cited_by_api_url': 'https://api.openalex.org/works?filter=cites:W2086031901', 'counts_by_year': [{'year': 2024, 'cited_by_count': 2}, {'year': 2023, 'cited_by_count': 1}, {'year': 2022, 'cited_by_count': 1}, {'year': 2020, 'cited_by_count': 1}, {'year': 2019, 'cited_by_count': 1}, {'year': 2017, 'cited_by_count': 1}, {'year': 2016, 'cited_by_count': 2}, {'year': 2014, 'cited_by_count': 3}, {'year': 2013, 'cited_by_count': 2}, {'year': 2012, 'cited_by_count': 5}], 'updated_date': '2025-01-05T00:57:22.062800', 'created_date': '2016-06-24'}